LEPOC|Ensembl=ENSLOCG00000016284.1|UniProtKB=W5NHI3 W5NHI3 PTHR12694:SF9 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TFIIA-ALPHA AND BETA-LIKE FACTOR cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 LEPOC|Ensembl=ENSLOCG00000017378.1|UniProtKB=W5NLH4 W5NLH4 PTHR24070:SF194 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;small GTPase-mediated signal transduction#GO:0007264;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;negative regulation of cell migration#GO:0030336 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906 LEPOC|Ensembl=ENSLOCG00000017578.1|UniProtKB=W5NM24 W5NM24 PTHR24559:SF440 TRANSPOSON TY3-I GAG-POL POLYPROTEIN RIBONUCLEASE H viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000013057.1|UniProtKB=W5N619 W5N619 PTHR13809:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-T2 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 LEPOC|Ensembl=ENSLOCG00000014664.1|UniProtKB=W5NBN9 W5NBN9 PTHR12400:SF106 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE C transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012874.1|UniProtKB=W5N5E2 W5N5E2 PTHR13723:SF169 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001246.1|UniProtKB=W5LZ56 W5LZ56 PTHR23330:SF9 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED PROLINE-RICH PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000013497.1|UniProtKB=W5N7N8 W5N7N8 PTHR10288:SF92 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;mRNA stabilization#GO:0048255;multicellular organism development#GO:0007275;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003292.1|UniProtKB=W5M675 W5M675 PTHR11267:SF198 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX6L sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000006290.1|UniProtKB=W5MGU2 W5MGU2 PTHR18929:SF93 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A2 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013353.1|UniProtKB=W5N7A3 W5N7A3 PTHR15036:SF33 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 2 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006469.1|UniProtKB=W5MHF7 W5MHF7 MED15 PTHR31804:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 LEPOC|Ensembl=ENSLOCG00000006054.1|UniProtKB=W5MG00 W5MG00 PTHR12011:SF454 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G5-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017553.1|UniProtKB=W5NLZ9 W5NLZ9 PTHR15314:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P20 RIBONUCLEASE P PROTEIN SUBUNIT P20 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002189.1|UniProtKB=W5M2F5 W5M2F5 PTHR15564:SF2 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of cell cycle#GO:0045786;developmental process#GO:0032502;multicellular organism development#GO:0007275;response to lipid#GO:0033993;negative regulation of mitotic cell cycle#GO:0045930;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;dendrite#GO:0030425;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015297.1|UniProtKB=W5NDW4 W5NDW4 PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;centrosome localization#GO:0051642;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;integrator complex#GO:0032039;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015921.1|UniProtKB=W5NG44 W5NG44 PTHR11848:SF141 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-2 PROPROTEIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;regulation of cell population proliferation#GO:0042127;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778 LEPOC|Ensembl=ENSLOCG00000009568.1|UniProtKB=W5MTI6 W5MTI6 PTHR16165:SF9 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 LEPOC|Ensembl=ENSLOCG00000006974.1|UniProtKB=W5MJ84 W5MJ84 PTHR10443:SF9 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 2 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009150.1|UniProtKB=W5MRZ6 W5MRZ6 PTHR12233:SF4 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015354.1|UniProtKB=W5NE36 W5NE36 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;microtubule nucleation#GO:0007020 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000004977.1|UniProtKB=W5MC80 W5MC80 PTHR21496:SF19 FERREDOXIN-RELATED SI:CH211-212D10.2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006894.1|UniProtKB=W5MIX7 W5MIX7 PTHR23267:SF343 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION 50S10.1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001652.1|UniProtKB=W5M0N7 W5M0N7 PTHR45723:SF1 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;preribosome#GO:0030684;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008039.1|UniProtKB=W5MN17 W5MN17 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;regulation of biological process#GO:0050789;lysosome localization#GO:0032418;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;Golgi organization#GO:0007030;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;regulation of protein localization#GO:0032880 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000017583.1|UniProtKB=W5NM29 W5NM29 PTHR12307:SF55 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3E phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000000432.1|UniProtKB=W5LWG5 W5LWG5 PTHR23184:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 14 TETRATRICOPEPTIDE REPEAT PROTEIN 14 LEPOC|Ensembl=ENSLOCG00000001296.1|UniProtKB=W5LZB1 W5LZB1 MMP7 PTHR10201:SF316 MATRIX METALLOPROTEINASE STROMELYSIN-2 PRECURSOR hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016341.1|UniProtKB=W5NHR3 W5NHR3 PTHR47464:SF1 MACOILIN MACOILIN-1 LEPOC|Ensembl=ENSLOCG00000016778.1|UniProtKB=W5NJC9 W5NJC9 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004509.1|UniProtKB=W5MAI4 W5MAI4 PTHR10529:SF342 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017034.1|UniProtKB=W5NK94 W5NK94 PTHR46375:SF4 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED KELCH-LIKE FAMILY, MEMBER 42 LEPOC|Ensembl=ENSLOCG00000012879.1|UniProtKB=W5N5E4 W5N5E4 MEX3C PTHR23285:SF8 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX3C RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011937.1|UniProtKB=W5N225 W5N225 PTHR11177:SF248 CHITINASE CHITOTRIOSIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017748.1|UniProtKB=W5NMJ3 W5NMJ3 PTHR11829:SF156 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001467.1|UniProtKB=W5LZX2 W5LZX2 PTHR21496:SF0 FERREDOXIN-RELATED RIESKE DOMAIN-CONTAINING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005855.1|UniProtKB=W5MFA9 W5MFA9 PTHR12782:SF5 MICROSOMAL PROSTAGLANDIN E SYNTHASE-2 PROSTAGLANDIN E SYNTHASE 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011082.1|UniProtKB=W5MZ05 W5MZ05 PTHR11670:SF32 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE carbon-oxygen lyase activity#GO:0016835;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;hydro-lyase activity#GO:0016836;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;lyase activity#GO:0016829;mRNA binding#GO:0003729 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 LEPOC|Ensembl=ENSLOCG00000010768.1|UniProtKB=W5MXT7 W5MXT7 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000012929.1|UniProtKB=W5N5L2 W5N5L2 PTHR17469:SF14 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID1 LEPOC|Ensembl=ENSLOCG00000017485.1|UniProtKB=W5NLT1 W5NLT1 GPR119 PTHR22750:SF7 G-PROTEIN COUPLED RECEPTOR GLUCOSE-DEPENDENT INSULINOTROPIC RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;phospholipid binding#GO:0005543;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011484.1|UniProtKB=W5N0F5 W5N0F5 FHL1 PTHR24205:SF14 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS 1 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000005111.1|UniProtKB=W5MCP5 W5MCP5 CLDN1 PTHR12002:SF92 CLAUDIN CLAUDIN-1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000013502.1|UniProtKB=W5N7P6 W5N7P6 PTHR15852:SF49 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG LEPOC|Ensembl=ENSLOCG00000006525.1|UniProtKB=W5MHM7 W5MHM7 PTHR24168:SF24 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 4 regulation of anatomical structure size#GO:0090066;negative regulation of protein polymerization#GO:0032272;negative regulation of biological process#GO:0048519;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000014565.1|UniProtKB=W5NBC7 W5NBC7 PTHR11199:SF3 STROMAL ANTIGEN COHESIN SUBUNIT SA-2 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cohesin complex#GO:0008278;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009934.1|UniProtKB=W5MUU0 W5MUU0 PTHR33721:SF3 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255B LEPOC|Ensembl=ENSLOCG00000014102.1|UniProtKB=W5N9R8 W5N9R8 PTHR45922:SF1 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014103.1|UniProtKB=W5N9R7 W5N9R7 PTHR12281:SF8 RP42 RELATED DCN1-LIKE PROTEIN 4 cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010692.1|UniProtKB=W5MXJ2 W5MXJ2 PTHR13923:SF23 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31A endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015311.1|UniProtKB=W5NDY0 W5NDY0 PTHR45882:SF2 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000922.1|UniProtKB=W5LY22 W5LY22 PTHR11767:SF17 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 LEPOC|Ensembl=ENSLOCG00000014529.1|UniProtKB=W5NB73 W5NB73 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 LEPOC|Ensembl=ENSLOCG00000006973.1|UniProtKB=W5MJ79 W5MJ79 PTHR21255:SF64 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 5 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012754.1|UniProtKB=W5N4Z0 W5N4Z0 PTHR13723:SF151 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 17 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001080.1|UniProtKB=W5LYL0 W5LYL0 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013669.1|UniProtKB=W5N896 W5N896 PTHR13524:SF2 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 14 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000016601.1|UniProtKB=W5NIP4 W5NIP4 PTHR15644:SF2 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS-ASSOCIATED TRANSMEMBRANE PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012635.1|UniProtKB=W5N4J5 W5N4J5 PTHR34260:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009903.1|UniProtKB=W5MUN9 W5MUN9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009931.1|UniProtKB=W5MUT6 W5MUT6 MSL3 PTHR10880:SF15 MORTALITY FACTOR 4-LIKE PROTEIN MSL COMPLEX SUBUNIT 3 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016671.1|UniProtKB=W5NIY5 W5NIY5 PTHR11486:SF69 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 23 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000006936.1|UniProtKB=W5MJ33 W5MJ33 PTHR10125:SF18 P2X PURINOCEPTOR P2X PURINOCEPTOR 4 monoatomic cation channel activity#GO:0005261;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008238.1|UniProtKB=W5MNQ4 W5MNQ4 PTHR11905:SF136 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>MDC9#P00090 LEPOC|Ensembl=ENSLOCG00000008543.1|UniProtKB=W5MPT8 W5MPT8 PTHR10730:SF28 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001887.1|UniProtKB=W5M1C9 W5M1C9 PTHR13070:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016244.1|UniProtKB=W5NHC6 W5NHC6 PTHR16266:SF4 WD REPEAT DOMAIN 9 PH-INTERACTING PROTEIN regulation of anatomical structure morphogenesis#GO:0022603;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cell shape#GO:0008360;regulation of cellular biosynthetic process#GO:0031326;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002400.1|UniProtKB=W5M353 W5M353 GOLM1 PTHR15896:SF8 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED GOLGI MEMBRANE PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011335.1|UniProtKB=W5MZX8 W5MZX8 PTHR10037:SF209 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;positive regulation of secretion#GO:0051047;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;action potential#GO:0001508;regulation of localization#GO:0032879;calcium ion transport#GO:0006816;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000006535.1|UniProtKB=W5MHP1 W5MHP1 PTHR12560:SF7 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003956.1|UniProtKB=W5M8M4 W5M8M4 PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013697.1|UniProtKB=W5N8D5 W5N8D5 ENTREP2 PTHR17615:SF6 PROTEIN FAM189A PROTEIN ENTREP2 LEPOC|Ensembl=ENSLOCG00000011596.1|UniProtKB=W5N0V4 W5N0V4 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017023.1|UniProtKB=W5NK84 W5NK84 PTHR23339:SF55 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014415.1|UniProtKB=W5NAV4 W5NAV4 PTHR23220:SF118 INTEGRIN ALPHA INTEGRIN ALPHA-X cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000004327.1|UniProtKB=W5MA86 W5MA86 PTHR24035:SF137 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 6 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000009476.1|UniProtKB=W5MT56 W5MT56 CFAP95 PTHR35069:SF1 PROTEIN C9ORF135 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 95 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001144.1|UniProtKB=W5LYT7 W5LYT7 PTHR12460:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1B basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000006321.1|UniProtKB=W5MGZ0 W5MGZ0 PTHR24353:SF68 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>cGK 1#P07149;Endothelin signaling pathway#P00019>PKG#P00567 LEPOC|Ensembl=ENSLOCG00000003154.1|UniProtKB=W5M5R0 W5M5R0 PPIL3 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000235.1|UniProtKB=W5LVV3 W5LVV3 PTHR10250:SF2 MICROSOMAL GLUTATHIONE S-TRANSFERASE ARACHIDONATE 5-LIPOXYGENASE-ACTIVATING PROTEIN glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 LEPOC|Ensembl=ENSLOCG00000014619.1|UniProtKB=W5NBI2 W5NBI2 PTHR31395:SF18 SHISA PROTEIN SHISA-2 HOMOLOG PRECURSOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015310.1|UniProtKB=W5NDY1 W5NDY1 PTHR48208:SF2 CENTROMERE PROTEIN I CENTROMERE PROTEIN I cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;protein-DNA complex organization#GO:0071824;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cell cycle#GO:0007049;chromatin organization#GO:0006325;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;chromatin remodeling#GO:0006338 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016353.1|UniProtKB=W5NHU2 W5NHU2 PTHR18879:SF20 CENTROSOMAL PROTEIN OF 290 KDA CENTROSOMAL PROTEIN OF 290 KDA LEPOC|Ensembl=ENSLOCG00000016515.1|UniProtKB=W5NIE6 W5NIE6 RTCB PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB HOMOLOG catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000009044.1|UniProtKB=W5MRM0 W5MRM0 PTHR13196:SF25 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1C lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007654.1|UniProtKB=W5MLP7 W5MLP7 PTHR11590:SF73 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE NOVEL TRANSGLUTAMINASE FAMILY PROTEIN-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007895.1|UniProtKB=W5MMI8 W5MMI8 PHAF1 PTHR13465:SF2 UPF0183 PROTEIN PHAGOSOME ASSEMBLY FACTOR 1 LEPOC|Ensembl=ENSLOCG00000005037.1|UniProtKB=W5MCF9 W5MCF9 TERB1 PTHR14014:SF0 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;telomere localization#GO:0034397;reproduction#GO:0000003;chromosome organization#GO:0051276;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;cell cycle#GO:0007049;chromosome localization#GO:0050000 LEPOC|Ensembl=ENSLOCG00000000820.1|UniProtKB=W5LXQ7 W5LXQ7 PTHR10652:SF0 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN cytoskeletal protein binding#GO:0008092;enzyme binding#GO:0019899;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000004616.1|UniProtKB=W5MAX3 W5MAX3 PTHR11592:SF134 GLUTATHIONE PEROXIDASE PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014213.1|UniProtKB=W5NA46 W5NA46 PTHR12352:SF13 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 1 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;extracellular matrix binding#GO:0050840;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604;extracellular region#GO:0005576;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010103.1|UniProtKB=W5MVG3 W5MVG3 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004432.1|UniProtKB=W5MA95 W5MA95 PTHR22969:SF13 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to tumor necrosis factor#GO:0034612;regulation of cellular process#GO:0050794;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>IKK#P00313;Toll receptor signaling pathway#P00054>IKKalpha#P01345;PDGF signaling pathway#P00047>Ikk#P01146;B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;Interleukin signaling pathway#P00036>Ikk#P00968;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 LEPOC|Ensembl=ENSLOCG00000009231.1|UniProtKB=W5MSA1 W5MSA1 PTHR22872:SF4 BTK-BINDING PROTEIN-RELATED RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000008613.1|UniProtKB=W5MQ14 W5MQ14 CSNK1G3 PTHR11909:SF509 CASEIN KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;import into cell#GO:0098657 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000006029.1|UniProtKB=W5MFX0 W5MFX0 MTERF4 PTHR13068:SF203 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 4, MITOCHONDRIAL cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;aromatic compound biosynthetic process#GO:0019438 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002237.1|UniProtKB=W5M2J4 W5M2J4 PTHR13738:SF15 TROPONIN I TROPONIN I, FAST SKELETAL MUSCLE blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003539.1|UniProtKB=W5M733 W5M733 PTHR11255:SF36 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003276.1|UniProtKB=W5M657 W5M657 PTHR43296:SF2 PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012389.1|UniProtKB=W5N3P4 W5N3P4 PTHR14076:SF9 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;monoatomic cation transport#GO:0006812;vasculature development#GO:0001944;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;protein localization to plasma membrane#GO:0072659;response to organic substance#GO:0010033;localization within membrane#GO:0051668;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;multicellular organism development#GO:0007275;tube development#GO:0035295;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;import into cell#GO:0098657 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002994.1|UniProtKB=W5M567 W5M567 PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004785.1|UniProtKB=W5MBI2 W5MBI2 PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 enzyme binding#GO:0019899;protein binding#GO:0005515;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;negative regulation of cell cycle process#GO:0010948;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012447.1|UniProtKB=W5N3W4 W5N3W4 PTHR11360:SF20 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016047.1|UniProtKB=W5NGK8 W5NGK8 PTHR13793:SF17 PHD FINGER PROTEINS BROMODOMAIN-CONTAINING PROTEIN 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010707.1|UniProtKB=W5MXK8 W5MXK8 IL1RL1 PTHR11890:SF26 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 1 transmembrane signal receptor#PC00197 p38 MAPK pathway#P05918>IL-1R#P06030 LEPOC|Ensembl=ENSLOCG00000003537.1|UniProtKB=W5M727 W5M727 PTHR10836:SF79 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, TESTIS-SPECIFIC oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 Huntington disease#P00029>GAPDH#P00810 LEPOC|Ensembl=ENSLOCG00000013586.1|UniProtKB=W5N7Z5 W5N7Z5 PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;snRNA binding#GO:0017069;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000014752.1|UniProtKB=W5NC09 W5NC09 PTHR24056:SF171 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011241.1|UniProtKB=W5MZK8 W5MZK8 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 LEPOC|Ensembl=ENSLOCG00000004653.1|UniProtKB=W5MB14 W5MB14 PTHR32026:SF23 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000000392.1|UniProtKB=W5LWC1 W5LWC1 PTHR23192:SF34 OLFACTOMEDIN-RELATED NOELIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011981.1|UniProtKB=W5N276 W5N276 PTHR23089:SF18 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000011068.1|UniProtKB=W5MYY3 W5MYY3 PTHR10351:SF75 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009364.1|UniProtKB=W5MSQ9 W5MSQ9 PTHR10656:SF47 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MB21D2 transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004105.1|UniProtKB=W5M946 W5M946 PTHR15336:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005890.1|UniProtKB=W5MFF5 W5MFF5 PTHR15107:SF3 RETINOBLASTOMA BINDING PROTEIN 8 RBBP8 N-TERMINAL-LIKE PROTEIN damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015760.1|UniProtKB=W5NFJ4 W5NFJ4 RDH13 PTHR43157:SF59 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 13 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015956.1|UniProtKB=W5NG88 W5NG88 SLX4IP PTHR28557:SF1 PROTEIN SLX4IP PROTEIN SLX4IP LEPOC|Ensembl=ENSLOCG00000003255.1|UniProtKB=W5M634 W5M634 C2orf76 PTHR18444:SF9 UPF0538 FAMILY MEMBER UPF0538 PROTEIN C2ORF76 LEPOC|Ensembl=ENSLOCG00000004148.1|UniProtKB=W5M9A7 W5M9A7 PTHR19359:SF95 CYTOCHROME B5 CYTOCHROME B5 TYPE B tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011519.1|UniProtKB=W5N0J8 W5N0J8 PTHR24356:SF221 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007311.1|UniProtKB=W5MKF0 W5MKF0 PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000001961.1|UniProtKB=W5M1L5 W5M1L5 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003588.1|UniProtKB=W5M7A2 W5M7A2 PTHR11783:SF9 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2B1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002817.1|UniProtKB=W5M4K9 W5M4K9 PTHR12570:SF14 FAMILY NOT NAMED NIPA-LIKE PROTEIN 3 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006110.1|UniProtKB=W5MG78 W5MG78 PTHR10414:SF35 ETHANOLAMINEPHOSPHOTRANSFERASE SELENOPROTEIN I transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000668.1|UniProtKB=W5LX81 W5LX81 PTHR14972:SF7 AGAP011572-PA PROTEIN FAM117A LEPOC|Ensembl=ENSLOCG00000011432.1|UniProtKB=W5N089 W5N089 PTHR31443:SF2 FAMILY NOT NAMED ZGC:153675 LEPOC|Ensembl=ENSLOCG00000018330.1|UniProtKB=W5NP72 W5NP72 PTHR35154:SF3 GBP PROTEIN GBP PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018352.1|UniProtKB=W5NP94 W5NP94 PTHR47981:SF17 RAB FAMILY RAS-RELATED PROTEIN RAB-9B lysosome organization#GO:0007040;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005301.1|UniProtKB=W5MDD2 W5MDD2 PTHR21468:SF1 HSD9 COILED-COIL DOMAIN-CONTAINING PROTEIN 83 LEPOC|Ensembl=ENSLOCG00000018315.1|UniProtKB=W5NP57 W5NP57 PTHR24241:SF135 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009907.1|UniProtKB=W5MUP7 W5MUP7 HS3ST1 PTHR10605:SF16 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001848.1|UniProtKB=W5M181 W5M181 PTHR21553:SF36 ALMS1-RELATED ALMS1 CENTROSOME AND BASAL BODY-ASSOCIATED PROTEIN-RELATED cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of centrosome cycle#GO:0046605;regulation of microtubule-based process#GO:0032886;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle assembly#GO:1902115;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of centriole replication#GO:0046599;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of centrosome duplication#GO:0010824;regulation of cell cycle process#GO:0010564 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016059.1|UniProtKB=W5NGN0 W5NGN0 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000003324.1|UniProtKB=W5M6C3 W5M6C3 PTHR21545:SF10 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT NUCLEAR RECEPTOR COREPRESSOR-LIKE PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013589.1|UniProtKB=W5N7Z9 W5N7Z9 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 neutral amino acid transport#GO:0015804;quaternary ammonium group transport#GO:0015697;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;organic cation transport#GO:0015695;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001445.1|UniProtKB=W5LZU7 W5LZU7 PTHR10185:SF26 PHOSPHOLIPASE D - RELATED PHOSPHOLIPASE D FAMILY, MEMBER 7 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000009643.1|UniProtKB=W5MTS9 W5MTS9 PTHR24020:SF36 COLLAGEN ALPHA COCHLIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000012659.1|UniProtKB=W5N4L9 W5N4L9 PTHR44427:SF5 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010142.1|UniProtKB=W5MVK5 W5MVK5 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015035.1|UniProtKB=W5ND01 W5ND01 PTHR12997:SF9 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE hydrolase activity#GO:0016787;inositol phosphate phosphatase activity#GO:0052745;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011020.1|UniProtKB=W5MYS0 W5MYS0 PTHR45983:SF1 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 22 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule modification#GO:0043412;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;protein modification process#GO:0036211;regulation of T cell activation#GO:0050863;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;negative regulation of multicellular organismal process#GO:0051241;nitrogen compound metabolic process#GO:0006807;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;negative regulation of cell adhesion#GO:0007162;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003593.1|UniProtKB=W5M7C2 W5M7C2 PTHR43900:SF3 GLUTATHIONE S-TRANSFERASE RHO GLUTATHIONE S-TRANSFERASE RHO glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277;ion binding#GO:0043167;anion binding#GO:0043168;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008036.1|UniProtKB=W5MN00 W5MN00 C4orf45 PTHR34833:SF1 GENE, 17359-RELATED GENE, 17359-RELATED LEPOC|Ensembl=ENSLOCG00000007345.1|UniProtKB=W5MKM5 W5MKM5 PTHR47096:SF1 MISSHAPEN LIKE KINASE 1 MISSHAPEN LIKE KINASE 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009057.1|UniProtKB=W5MRM9 W5MRM9 PTHR10264:SF127 BAND 7 PROTEIN-RELATED PODOCIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006870.1|UniProtKB=W5MIV0 W5MIV0 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000018118.1|UniProtKB=W5NNL0 W5NNL0 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000006243.1|UniProtKB=W5MGN2 W5MGN2 PTHR24006:SF644 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein stability#GO:0031647;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014679.1|UniProtKB=W5NBR0 W5NBR0 PTHR12435:SF2 FAMILY NOT NAMED PROTEIN KTI12 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000017816.1|UniProtKB=W5NMR1 W5NMR1 PTHR23334:SF3 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN DELTA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000004662.1|UniProtKB=W5MB21 W5MB21 PTHR21093:SF4 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1A LEPOC|Ensembl=ENSLOCG00000010312.1|UniProtKB=W5MW80 W5MW80 PTHR12120:SF9 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of JNK cascade#GO:0046330;regulation of JNK cascade#GO:0046328;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005860.1|UniProtKB=W5MFC1 W5MFC1 PTHR18945:SF61 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT DELTA monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>delta#P01092 LEPOC|Ensembl=ENSLOCG00000012399.1|UniProtKB=W5N3R7 W5N3R7 PTHR16199:SF4 CONDENSIN-2 COMPLEX SUBUNIT G2 CONDENSIN-2 COMPLEX SUBUNIT G2 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004091.1|UniProtKB=W5M923 W5M923 PTHR24543:SF317 MULTICOPPER OXIDASE-RELATED LACTADHERIN oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005680.1|UniProtKB=W5MER5 W5MER5 PTHR18966:SF417 IONOTROPIC GLUTAMATE RECEPTOR KAINATE BINDING PROTEIN-RELATED transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796 LEPOC|Ensembl=ENSLOCG00000012136.1|UniProtKB=W5N2S6 W5N2S6 PTHR24058:SF103 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004471.1|UniProtKB=W5MAD6 W5MAD6 PTHR14709:SF2 GLUTAMINE AND SERINE-RICH PROTEIN 1-RELATED GLUTAMINE AND SERINE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017947.1|UniProtKB=W5NN41 W5NN41 PTHR46375:SF3 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000015638.1|UniProtKB=W5NF42 W5NF42 PTHR11352:SF0 PROLIFERATING CELL NUCLEAR ANTIGEN PROLIFERATING CELL NUCLEAR ANTIGEN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 LEPOC|Ensembl=ENSLOCG00000014663.1|UniProtKB=W5NBP4 W5NBP4 PTHR10590:SF22 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM_NUCLEOSIDE COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;carbohydrate derivative transmembrane transporter activity#GO:1901505;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;nucleobase-containing compound transmembrane transporter activity#GO:0015932;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011629.1|UniProtKB=W5N0Y3 W5N0Y3 PTHR14024:SF25 PERILIPIN PERILIPIN-2 localization#GO:0051179;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000146.1|UniProtKB=W5LVK3 W5LVK3 PTHR47306:SF2 SI:CH211-178J18.4-RELATED CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003159.1|UniProtKB=W5M5S4 W5M5S4 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010179.1|UniProtKB=W5MVQ3 W5MVQ3 PTHR11860:SF118 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011202.1|UniProtKB=W5MZG0 W5MZG0 PTHR12098:SF5 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005016.1|UniProtKB=W5MCD2 W5MCD2 PTHR11818:SF50 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001557.1|UniProtKB=W5M089 W5M089 PTHR45911:SF3 C2 DOMAIN-CONTAINING PROTEIN DYSFERLIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000010199.1|UniProtKB=W5MVT5 W5MVT5 PTHR12178:SF11 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 1 regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of protein metabolic process#GO:0051246;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008563.1|UniProtKB=W5MPV6 W5MPV6 PTHR14402:SF8 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 4 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein insertion into membrane#GO:0051205 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000391.1|UniProtKB=W5LWB8 W5LWB8 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014706.1|UniProtKB=W5NBV1 W5NBV1 PTHR21483:SF18 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003310.1|UniProtKB=W5M6A5 W5M6A5 PTHR19818:SF131 ZINC FINGER PROTEIN ZIC AND GLI METAL REGULATORY TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017045.1|UniProtKB=W5NKB4 W5NKB4 PTHR12011:SF40 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;system development#GO:0048731;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;signaling#GO:0023052 synapse#GO:0045202;extracellular region#GO:0005576;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 p53 pathway#P00059>BAI-1#G04699 LEPOC|Ensembl=ENSLOCG00000017221.1|UniProtKB=W5NKY7 W5NKY7 PTHR45972:SF3 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000009695.1|UniProtKB=W5MTY1 W5MTY1 PTHR45682:SF4 AGAP008228-PA SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000005064.1|UniProtKB=W5MCI9 W5MCI9 PTHR11267:SF29 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate specification#GO:0001708;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;tube development#GO:0035295;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;angiogenesis#GO:0001525;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000006965.1|UniProtKB=W5MJ66 W5MJ66 PTHR21456:SF2 FAMILY WITH SEQUENCE SIMILARITY 102 EARLY ESTROGEN-INDUCED GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000007777.1|UniProtKB=W5MM41 W5MM41 PTHR45630:SF2 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A2 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 vesicle fusion#GO:0006906;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;macroautophagy#GO:0016236;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;vacuole organization#GO:0007033;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of mitochondrion organization#GO:0010821;catabolic process#GO:0009056;vesicle organization#GO:0016050;organelle fusion#GO:0048284;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;transmembrane transport#GO:0055085;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005432.1|UniProtKB=W5MDU5 W5MDU5 PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RYK signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007308.1|UniProtKB=W5MKE4 W5MKE4 PTHR14388:SF23 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SI:CH73-109I22.2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008103.1|UniProtKB=W5MN81 W5MN81 PTHR45939:SF5 PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED PEROXISOMAL MEMBRANE PROTEIN PMP34 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010713.1|UniProtKB=W5MXL2 W5MXL2 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000017133.1|UniProtKB=W5NKL8 W5NKL8 PTHR12619:SF28 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003631.1|UniProtKB=W5M7E4 W5M7E4 PTHR24006:SF899 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011822.1|UniProtKB=W5N1P0 W5N1P0 PTHR45620:SF23 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 2 RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003352.1|UniProtKB=W5M6F7 W5M6F7 PTHR12241:SF39 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL9-RELATED cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001725.1|UniProtKB=W5M0T2 W5M0T2 PTHR46963:SF3 SIMILAR TO RIKEN CDNA E130308A19 DUF3504 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013717.1|UniProtKB=W5N8G0 W5N8G0 PTHR12994:SF16 SECERNIN SECERNIN-2 LEPOC|Ensembl=ENSLOCG00000009367.1|UniProtKB=W5MSR5 W5MSR5 PTHR23277:SF12 NECTIN-RELATED NECTIN-3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;apical junction complex#GO:0043296 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001685.1|UniProtKB=W5M0S5 W5M0S5 PTHR24006:SF722 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008922.1|UniProtKB=W5MR71 W5MR71 PTHR12694:SF7 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 LEPOC|Ensembl=ENSLOCG00000010080.1|UniProtKB=W5MVB7 W5MVB7 PTHR10390:SF12 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;sensory system development#GO:0048880;visual system development#GO:0150063;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009317.1|UniProtKB=W5MSK8 W5MSK8 IL12B PTHR48485:SF4 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT BETA LEPOC|Ensembl=ENSLOCG00000015741.1|UniProtKB=W5NFG8 W5NFG8 PTHR12241:SF118 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL2-RELATED cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002449.1|UniProtKB=W5M3C3 W5M3C3 PTHR10720:SF2 HEME OXYGENASE HEME OXYGENASE 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;cellular nitrogen compound metabolic process#GO:0034641;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular nitrogen compound catabolic process#GO:0044270;response to stimulus#GO:0050896;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;cellular catabolic process#GO:0044248 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015635.1|UniProtKB=W5NF44 W5NF44 PTHR22625:SF34 PLEXIN PLEXIN-A4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015998.1|UniProtKB=W5NGE3 W5NGE3 PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cell projection#GO:0042995;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000016971.1|UniProtKB=W5NK20 W5NK20 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003485.1|UniProtKB=W5M6X3 W5M6X3 PTHR47980:SF33 LD44762P RAS-RELATED PROTEIN RAB-8A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;secretion#GO:0046903;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;secretion by cell#GO:0032940;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;protein-containing complex localization#GO:0031503 synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;clathrin-coated vesicle#GO:0030136;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;trans-Golgi network transport vesicle#GO:0030140;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Huntington disease#P00029>Rab8#P00783 LEPOC|Ensembl=ENSLOCG00000011453.1|UniProtKB=W5N0B0 W5N0B0 PTHR16131:SF2 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 LEPOC|Ensembl=ENSLOCG00000004031.1|UniProtKB=W5M8W3 W5M8W3 PTHR45838:SF3 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2B N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;histone H3K4 methyltransferase activity#GO:0042800;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000003461.1|UniProtKB=W5M6V3 W5M6V3 SEC16A PTHR13402:SF13 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16A localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;protein localization to endoplasmic reticulum#GO:0070972;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000013418.1|UniProtKB=W5N7D9 W5N7D9 WDR72 PTHR44099:SF2 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 72 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014450.1|UniProtKB=W5NAX5 W5NAX5 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;mitochondrial transmembrane transport#GO:1990542;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;protein folding#GO:0006457;protein transport#GO:0015031 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007709.1|UniProtKB=W5MLU5 W5MLU5 PTHR11394:SF72 TASTE RECEPTOR TYPE 2 OLFACTORY RECEPTOR CLASS A-LIKE PROTEIN 4 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012437.1|UniProtKB=W5N3U9 W5N3U9 PTHR28659:SF1 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 3 LEPOC|Ensembl=ENSLOCG00000012149.1|UniProtKB=W5N2V4 W5N2V4 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004174.1|UniProtKB=W5M9E0 W5M9E0 PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000007294.1|UniProtKB=W5MKC4 W5MKC4 PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002300.1|UniProtKB=W5M2T9 W5M2T9 SCYL1 PTHR12984:SF3 SCY1-RELATED S/T PROTEIN KINASE-LIKE N-TERMINAL KINASE-LIKE PROTEIN non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001643.1|UniProtKB=W5M0I4 W5M0I4 PTHR13144:SF0 TEX261 PROTEIN PROTEIN TEX261 cargo receptor activity#GO:0038024 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000011610.1|UniProtKB=W5N0W1 W5N0W1 PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012732.1|UniProtKB=W5N4W5 W5N4W5 PTHR46532:SF13 MALE FERTILITY FACTOR KL5 CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000012708.1|UniProtKB=W5N4S3 W5N4S3 PTHR11958:SF109 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 LEPOC|Ensembl=ENSLOCG00000012992.1|UniProtKB=W5N5U1 W5N5U1 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010908.1|UniProtKB=W5MYB2 W5MYB2 PTHR33053:SF26 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015438.1|UniProtKB=W5NEE0 W5NEE0 PTHR10845:SF196 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 17 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 LEPOC|Ensembl=ENSLOCG00000003825.1|UniProtKB=W5M856 W5M856 PTHR23037:SF7 CYTOKINE RECEPTOR INTERLEUKIN-21 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003135.1|UniProtKB=W5M5Q7 W5M5Q7 PTHR31432:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000016561.1|UniProtKB=W5NIJ3 W5NIJ3 PTHR23043:SF22 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008853.1|UniProtKB=W5MQX2 W5MQX2 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008499.1|UniProtKB=W5MPP6 W5MPP6 PTHR21683:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000007148.1|UniProtKB=W5MJU6 W5MJU6 PTHR15614:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000009089.1|UniProtKB=W5MRS4 W5MRS4 LIX1L PTHR31139:SF3 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG LIX1-LIKE PROTEIN process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;protein-containing complex organization#GO:0043933;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagosome maturation#GO:0097352;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017169.1|UniProtKB=W5NKR3 W5NKR3 PTHR23351:SF58 FOS TRANSCRIPTION FACTOR-RELATED FOS-LIKE 2, AP-1 TRANSCRIPTION FACTOR SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000011377.1|UniProtKB=W5N031 W5N031 PTHR45742:SF3 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C9 activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000000365.1|UniProtKB=W5LW91 W5LW91 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003126.1|UniProtKB=W5M5M4 W5M5M4 PTHR22750:SF56 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006069.1|UniProtKB=W5MG19 W5MG19 PTHR10609:SF14 BIOTINIDASE-RELATED BIOTINIDASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009540.1|UniProtKB=W5MTE9 W5MTE9 PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N7 METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000012294.1|UniProtKB=W5N3B6 W5N3B6 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016068.1|UniProtKB=W5NGP4 W5NGP4 PTHR13667:SF5 HOMOLOC-13 WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG LEPOC|Ensembl=ENSLOCG00000008251.1|UniProtKB=W5MNQ5 W5MNQ5 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006842.1|UniProtKB=W5MIS3 W5MIS3 PTHR11827:SF54 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;monoatomic cation transport#GO:0006812;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cell communication#GO:0007154;cellular component organization#GO:0016043;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;potassium ion import across plasma membrane#GO:1990573 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011779.1|UniProtKB=W5N1I1 W5N1I1 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004617.1|UniProtKB=W5MAX5 W5MAX5 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 elongator holoenzyme complex#GO:0033588;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000009060.1|UniProtKB=W5MRN5 W5MRN5 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000003525.1|UniProtKB=W5M726 W5M726 PTHR22983:SF6 PROTEIN KINASE RELATED SERINE_THREONINE-PROTEIN KINASE 36 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEK1-2#P00559;PDGF signaling pathway#P00047>MAPKAPK2#P01157;FGF signaling pathway#P00021>MEK1-2#P00642;Hedgehog signaling pathway#P00025>Fused#P00686 LEPOC|Ensembl=ENSLOCG00000014330.1|UniProtKB=W5NAJ3 W5NAJ3 PTHR10953:SF4 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000009629.1|UniProtKB=W5MTR3 W5MTR3 PTHR43389:SF5 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003986.1|UniProtKB=W5M8Q1 W5M8Q1 PTHR15228:SF22 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 22 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016656.1|UniProtKB=W5NIW8 W5NIW8 GALNT8 PTHR11675:SF50 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 8-RELATED transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000674.1|UniProtKB=W5LX88 W5LX88 PTHR11153:SF14 SIDEROFLEXIN SIDEROFLEXIN-2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002020.1|UniProtKB=W5M1T2 W5M1T2 PTHR33504:SF2 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 PROTEIN MFI dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012721.1|UniProtKB=W5N4U8 W5N4U8 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014140.1|UniProtKB=W5N9V8 W5N9V8 PTHR19964:SF14 MULTIPLE PDZ DOMAIN PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LNX transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 LEPOC|Ensembl=ENSLOCG00000013859.1|UniProtKB=W5N8Y2 W5N8Y2 PTHR14399:SF12 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000009028.1|UniProtKB=W5MRJ3 W5MRJ3 PTHR12868:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012209.1|UniProtKB=W5N312 W5N312 PTHR24248:SF146 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016447.1|UniProtKB=W5NI59 W5NI59 HAAO PTHR15497:SF1 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002452.1|UniProtKB=W5M3C4 W5M3C4 PTHR10492:SF57 FAMILY NOT NAMED ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000006951.1|UniProtKB=W5MJ48 W5MJ48 PTHR21732:SF0 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000014366.1|UniProtKB=W5NAN0 W5NAN0 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012331.1|UniProtKB=W5N3H7 W5N3H7 PTHR13723:SF189 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 12 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014667.1|UniProtKB=W5NBP6 W5NBP6 PTHR47437:SF3 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;JNK cascade#GO:0007254;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013444.1|UniProtKB=W5N7G5 W5N7G5 PTHR10370:SF0 ERYTHROPOIETIN ERYTHROPOIETIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000004234.1|UniProtKB=W5M9K6 W5M9K6 PTHR11011:SF119 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011867.1|UniProtKB=W5N1T9 W5N1T9 PTHR48012:SF19 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCK#P00268 LEPOC|Ensembl=ENSLOCG00000010885.1|UniProtKB=W5MY85 W5MY85 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009238.1|UniProtKB=W5MSB0 W5MSB0 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003353.1|UniProtKB=W5M6F0 W5M6F0 PTHR46109:SF2 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;pre-miRNA processing#GO:0031054;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013290.1|UniProtKB=W5N6W5 W5N6W5 PTHR13720:SF14 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000611.1|UniProtKB=W5LX14 W5LX14 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000004099.1|UniProtKB=W5M936 W5M936 PTHR11818:SF6 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN S structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006167.1|UniProtKB=W5MGE0 W5MGE0 PTHR12756:SF41 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 2 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006414.1|UniProtKB=W5MH91 W5MH91 PTHR10218:SF217 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-15 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Wnt signaling pathway#P00057>Galpha#P01451;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732 LEPOC|Ensembl=ENSLOCG00000011641.1|UniProtKB=W5N104 W5N104 PTHR23167:SF35 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010654.1|UniProtKB=W5MXE3 W5MXE3 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010911.1|UniProtKB=W5MYD6 W5MYD6 PTHR11036:SF27 SEMAPHORIN SEMAPHORIN-3F molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000017767.1|UniProtKB=W5NML2 W5NML2 PTHR12002:SF181 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000012009.1|UniProtKB=W5N2C4 W5N2C4 PTHR24416:SF49 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;regulation of cell migration#GO:0030334;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;positive regulation of cell motility#GO:2000147;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of cell motility#GO:2000145;blood vessel morphogenesis#GO:0048514;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cell migration#GO:0030335;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;blood vessel development#GO:0001568;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 LEPOC|Ensembl=ENSLOCG00000006128.1|UniProtKB=W5MG98 W5MG98 PTHR14326:SF44 TARGETING PROTEIN FOR XKLP2 TARGETING PROTEIN FOR XKLP2 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000002914.1|UniProtKB=W5M4W6 W5M4W6 PTHR45917:SF1 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 1 transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010291.1|UniProtKB=W5MW43 W5MW43 PTHR14949:SF25 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 CRYPTIC FAMILY PROTEIN 1B-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;heart development#GO:0007507;signal transduction#GO:0007165;left/right pattern formation#GO:0060972;circulatory system development#GO:0072359;animal organ development#GO:0048513;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;system development#GO:0048731;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;blood vessel development#GO:0001568;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013604.1|UniProtKB=W5N818 W5N818 PTHR10658:SF55 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004061.1|UniProtKB=W5M914 W5M914 PTHR31826:SF8 NICALIN BOS COMPLEX SUBUNIT NCLN biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007657.1|UniProtKB=W5MLM8 W5MLM8 PTHR19432:SF7 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 4 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;carbohydrate transmembrane transporter activity#GO:0015144;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015672.1|UniProtKB=W5NF82 W5NF82 PTHR45652:SF8 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT LIGHT POLYPEPTIDE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;synapse#GO:0045202;intermediate filament#GO:0005882;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;postsynapse#GO:0098794;cytoskeleton#GO:0005856;cell projection#GO:0042995 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000005833.1|UniProtKB=W5MF87 W5MF87 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000010719.1|UniProtKB=W5MXM4 W5MXM4 STRADB PTHR48014:SF13 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN BETA protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;activation of protein kinase activity#GO:0032147;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;organic substance transport#GO:0071702;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein export from nucleus#GO:0006611;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;regulation of kinase activity#GO:0043549;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;cellular macromolecule localization#GO:0070727;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;nuclear export#GO:0051168;regulation of protein phosphorylation#GO:0001932;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;positive regulation of kinase activity#GO:0033674;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002084.1|UniProtKB=W5M212 W5M212 PTHR12101:SF15 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;muscle organ development#GO:0007517;heart development#GO:0007507;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;skeletal muscle tissue development#GO:0007519 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012817.1|UniProtKB=W5N565 W5N565 PTHR15535:SF15 TRANSMEMBRANE PROTEIN 2-RELATED CELL MIGRATION-INDUCING AND HYALURONAN-BINDING PROTEIN LEPOC|Ensembl=ENSLOCG00000000601.1|UniProtKB=W5LX04 W5LX04 PTHR15196:SF0 CILIARY NEUROTROPHIC FACTOR CILIARY NEUROTROPHIC FACTOR LEPOC|Ensembl=ENSLOCG00000010387.1|UniProtKB=W5MWI0 W5MWI0 PTHR14738:SF29 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018346.1|UniProtKB=W5NP88 W5NP88 PTHR16703:SF3 CLAUDIN-12 CLAUDIN-12 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002101.1|UniProtKB=W5M231 W5M231 PTHR48012:SF15 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCK#P00268 LEPOC|Ensembl=ENSLOCG00000010241.1|UniProtKB=W5MVY0 W5MVY0 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015984.1|UniProtKB=W5NGC2 W5NGC2 PTHR11851:SF103 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT BETA hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;protein processing involved in protein targeting to mitochondrion#GO:0006627;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein maturation#GO:0051604;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007355.1|UniProtKB=W5MKK7 W5MKK7 PTHR22881:SF12 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003758.1|UniProtKB=W5M7Y0 W5M7Y0 PTHR10983:SF9 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GAMMA transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000007281.1|UniProtKB=W5MKB1 W5MKB1 PTHR45915:SF5 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011954.1|UniProtKB=W5N241 W5N241 PTHR24056:SF459 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 13 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;protein modification process#GO:0036211;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016804.1|UniProtKB=W5NJG0 W5NJG0 PTHR24369:SF172 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005182.1|UniProtKB=W5MCX8 W5MCX8 PTHR15077:SF10 FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD FAS-ASSOCIATED DEATH DOMAIN PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;positive regulation of response to stimulus#GO:0048584;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of defense response#GO:0031347;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of immune system process#GO:0002682;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of biological process#GO:0048518;signaling#GO:0023052 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 FAS signaling pathway#P00020>FADD#P00622;Apoptosis signaling pathway#P00006>FADD#P00327 LEPOC|Ensembl=ENSLOCG00000011094.1|UniProtKB=W5MZ24 W5MZ24 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011717.1|UniProtKB=W5N199 W5N199 PTHR24240:SF77 OPSIN VISUAL PIGMENT-LIKE RECEPTOR PEROPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003052.1|UniProtKB=W5M5D7 W5M5D7 PTHR42714:SF2 TRNA MODIFICATION GTPASE GTPBP3 TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000015065.1|UniProtKB=W5ND33 W5ND33 PTHR12675:SF3 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012251.1|UniProtKB=W5N367 W5N367 PTHR12015:SF202 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 14 cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004586.1|UniProtKB=W5MAT6 W5MAT6 PTHR24391:SF15 HISTONE H4 TRANSCRIPTION FACTOR-RELATED MBD2 (METHYL-CPG-BINDING PROTEIN)-INTERACTING ZINC FINGER PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015818.1|UniProtKB=W5NFR4 W5NFR4 PTHR45476:SF4 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 5 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001740.1|UniProtKB=W5M0Y9 W5M0Y9 PTHR22589:SF55 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, BRAIN ISOFORM palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012107.1|UniProtKB=W5N2N4 W5N2N4 PTHR21472:SF18 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000006460.1|UniProtKB=W5MHE4 W5MHE4 PTHR22812:SF85 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 5 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005632.1|UniProtKB=W5MEI7 W5MEI7 PTHR46126:SF1 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002462.1|UniProtKB=W5M3D7 W5M3D7 PTHR10807:SF52 MYOTUBULARIN-RELATED MYOTUBULARIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000016846.1|UniProtKB=W5NJL4 W5NJL4 PTHR11006:SF47 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 8 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;protein metabolic process#GO:0019538;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006907.1|UniProtKB=W5MIZ5 W5MIZ5 PTHR11339:SF264 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-6 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013920.1|UniProtKB=W5N951 W5N951 C15orf61 PTHR34651:SF1 SIMILAR TO ENSANGP00000021391 SIMILAR TO ENSANGP00000021391 LEPOC|Ensembl=ENSLOCG00000008334.1|UniProtKB=W5MP12 W5MP12 PTHR13069:SF35 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA METHYLTRANSFERASE 9-LIKE PROTEIN-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003286.1|UniProtKB=W5M673 W5M673 PTHR45787:SF2 LD11652P RHOMBOTIN-1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010193.1|UniProtKB=W5MVR8 W5MVR8 PTHR10164:SF5 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001801.1|UniProtKB=W5M158 W5M158 PTHR24346:SF42 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015467.1|UniProtKB=W5NEH7 W5NEH7 PTHR10829:SF5 CORTACTIN AND DREBRIN HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;cell migration#GO:0016477;regulation of protein polymerization#GO:0032271 supramolecular complex#GO:0099080;cortical cytoskeleton#GO:0030863;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000010835.1|UniProtKB=W5MY87 W5MY87 PTHR24023:SF568 COLLAGEN ALPHA COLLAGEN ALPHA-2(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;supramolecular fiber#GO:0099512 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011922.1|UniProtKB=W5N204 W5N204 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38_39) SYNTHASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000010545.1|UniProtKB=W5MX22 W5MX22 PTHR11849:SF77 ETS TRANSCRIPTION FACTOR ETV7 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000014038.1|UniProtKB=W5N9J4 W5N9J4 PTHR47027:SF29 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004372.1|UniProtKB=W5MA19 W5MA19 PTHR10802:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001009.1|UniProtKB=W5LYD0 W5LYD0 PTHR12214:SF4 GC-RICH SEQUENCE DNA-BINDING FACTOR INTRON LARGE COMPLEX COMPONENT GCFC2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016573.1|UniProtKB=W5NIL2 W5NIL2 NLRC4 PTHR47688:SF1 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000002147.1|UniProtKB=W5M290 W5M290 PTHR24103:SF695 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-18P12.4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013679.1|UniProtKB=W5N8A3 W5N8A3 PTHR18884:SF128 SEPTIN SI:CH211-282J17.12-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017699.1|UniProtKB=W5NME5 W5NME5 PTHR24366:SF41 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000012893.1|UniProtKB=W5N5I0 W5N5I0 PTHR18966:SF109 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009482.1|UniProtKB=W5MT68 W5MT68 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008965.1|UniProtKB=W5MRB3 W5MRB3 PTHR12214:SF2 GC-RICH SEQUENCE DNA-BINDING FACTOR PAX3- AND PAX7-BINDING PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000060.1|UniProtKB=W5LVB3 W5LVB3 C4orf54 PTHR33775:SF4 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED CHROMOSOME 4 OPEN READING FRAME 54 LEPOC|Ensembl=ENSLOCG00000014098.1|UniProtKB=W5N9S9 W5N9S9 PTHR10730:SF7 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER MULTIFUNCTIONAL PROCOLLAGEN LYSINE HYDROXYLASE AND GLYCOSYLTRANSFERASE LH3 transferase activity#GO:0016740;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;glucosyltransferase activity#GO:0046527;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;hexosyltransferase activity#GO:0016758 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein hydroxylation#GO:0018126;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016387.1|UniProtKB=W5NHX9 W5NHX9 PTHR45712:SF13 AGAP008170-PA KERATOCAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005647.1|UniProtKB=W5MEL0 W5MEL0 PTHR47061:SF1 LYR MOTIF-CONTAINING PROTEIN 9 LYR MOTIF-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000005371.1|UniProtKB=W5MDL9 W5MDL9 PTHR24271:SF87 KALLIKREIN-RELATED ARGININE ESTERASE-LIKE-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016547.1|UniProtKB=W5NIH8 W5NIH8 SLC16A7 PTHR11360:SF25 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 2 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007708.1|UniProtKB=W5MLV2 W5MLV2 PTHR12625:SF2 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LMBR1L signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015754.1|UniProtKB=W5NFI6 W5NFI6 PTHR28630:SF32 FAMILY NOT NAMED SELENOPROTEIN L oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000003449.1|UniProtKB=W5M6T8 W5M6T8 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000015927.1|UniProtKB=W5NG52 W5NG52 PTHR45627:SF30 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 3 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 LEPOC|Ensembl=ENSLOCG00000006448.1|UniProtKB=W5MHE2 W5MHE2 PTHR15696:SF0 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 TELOMERASE-BINDING PROTEIN EST1A telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000993.1|UniProtKB=W5LYA9 W5LYA9 PTHR13999:SF31 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN IFITM1-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011975.1|UniProtKB=W5N263 W5N263 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000000158.1|UniProtKB=W5LVP7 W5LVP7 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010165.1|UniProtKB=W5MVP2 W5MVP2 KIF9 PTHR24115:SF191 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF9 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007801.1|UniProtKB=W5MM60 W5MM60 PTHR32297:SF1 SODIUM CHANNEL MODIFIER 1 SODIUM CHANNEL MODIFIER 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010999.1|UniProtKB=W5MYN2 W5MYN2 PTHR24340:SF26 HOMEOBOX PROTEIN NKX NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015822.1|UniProtKB=W5NFS1 W5NFS1 PTHR15499:SF3 HMG BOX-CONTAINING PROTEIN 1 HMG BOX-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000013608.1|UniProtKB=W5N825 W5N825 PTHR42918:SF9 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016182.1|UniProtKB=W5NH37 W5NH37 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;chromosome organization#GO:0051276;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008579.1|UniProtKB=W5MPX4 W5MPX4 PTHR21705:SF6 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1A LEPOC|Ensembl=ENSLOCG00000010323.1|UniProtKB=W5MW89 W5MW89 PTHR24245:SF7 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 78 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005511.1|UniProtKB=W5ME43 W5ME43 SLFN5 PTHR12155:SF30 SCHLAFEN PROTEIN SLFN14 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008088.1|UniProtKB=W5MN61 W5MN61 PTHR10339:SF25 ADP-RIBOSYLTRANSFERASE SECRETED EXOENZYME S transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005901.1|UniProtKB=W5MFH2 W5MFH2 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA binding#GO:0003723;RNA polymerase binding#GO:0070063;binding#GO:0005488;organic cyclic compound binding#GO:0097159;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;mRNA binding#GO:0003729;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002121.1|UniProtKB=W5M250 W5M250 PTHR23411:SF42 TAPASIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000335.1|UniProtKB=W5LWA2 W5LWA2 PTHR16675:SF191 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, F10 ALPHA CHAIN-LIKE-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000008856.1|UniProtKB=W5MQW2 W5MQW2 PTHR16076:SF8 CYTOSKELETON ASSOCIATED PROTEIN 2-RELATED CYTOSKELETON-ASSOCIATED PROTEIN 2 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of protein-containing complex disassembly#GO:0043244;regulation of cellular component organization#GO:0051128;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein depolymerization#GO:1901879;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein-containing complex disassembly#GO:0043242;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000017253.1|UniProtKB=W5NL32 W5NL32 PTHR11984:SF105 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000004240.1|UniProtKB=W5M9M9 W5M9M9 PTHR11946:SF109 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005583.1|UniProtKB=W5MEF7 W5MEF7 PTHR23005:SF4 RETINITIS PIGMENTOSA 1 PROTEIN OXYGEN-REGULATED PROTEIN 1 cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;retina development in camera-type eye#GO:0060041;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;visual system development#GO:0150063;sensory system development#GO:0048880;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;eye development#GO:0001654;neuron development#GO:0048666;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000015800.1|UniProtKB=W5NFP1 W5NFP1 PTHR14592:SF10 UNCHARACTERIZED FAM3 PROTEIN FAM3C extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 LEPOC|Ensembl=ENSLOCG00000003290.1|UniProtKB=W5M686 W5M686 PTHR11200:SF300 INOSITOL 5-PHOSPHATASE TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000008301.1|UniProtKB=W5MNX5 W5MNX5 PTHR10165:SF13 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;phospholipid dephosphorylation#GO:0046839;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;organophosphate metabolic process#GO:0019637;generation of neurons#GO:0048699;cellular lipid metabolic process#GO:0044255 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009726.1|UniProtKB=W5MU36 W5MU36 DOCK2 PTHR45653:SF6 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;syncytium formation by plasma membrane fusion#GO:0000768;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;syncytium formation#GO:0006949;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010069.1|UniProtKB=W5MVE4 W5MVE4 PTHR13902:SF53 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008527.1|UniProtKB=W5MPR4 W5MPR4 PTHR11595:SF26 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012343.1|UniProtKB=W5N3I9 W5N3I9 PTHR44472:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1 AND CUL4 ASSOCIATED FACTOR 4 LEPOC|Ensembl=ENSLOCG00000006137.1|UniProtKB=W5MGA7 W5MGA7 PTHR46472:SF1 NUCLEOREDOXIN NUCLEOREDOXIN protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of response to stimulus#GO:0048585;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of protein modification process#GO:0031400;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein ubiquitination#GO:0031397;regulation of Wnt signaling pathway#GO:0030111;negative regulation of macromolecule metabolic process#GO:0010605;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003688.1|UniProtKB=W5M7M5 W5M7M5 PTHR15654:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 113 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000000022.1|UniProtKB=W5LV68 W5LV68 PTHR11360:SF318 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008604.1|UniProtKB=W5MQ01 W5MQ01 PTHR24243:SF235 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005728.1|UniProtKB=W5MEW2 W5MEW2 PTHR10005:SF15 SKI ONCOGENE-RELATED SKI ONCOGENE cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;negative regulation of BMP signaling pathway#GO:0030514;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000012701.1|UniProtKB=W5N4S0 W5N4S0 PTHR11958:SF109 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 LEPOC|Ensembl=ENSLOCG00000014552.1|UniProtKB=W5NBA4 W5NBA4 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000012511.1|UniProtKB=W5N445 W5N445 PTHR24247:SF273 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013220.1|UniProtKB=W5N6M6 W5N6M6 TC2N PTHR46887:SF1 TANDEM C2 DOMAINS NUCLEAR PROTEIN TANDEM C2 DOMAINS NUCLEAR PROTEIN LEPOC|Ensembl=ENSLOCG00000017080.1|UniProtKB=W5NKF1 W5NKF1 HDHD5 PTHR14269:SF17 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003821.1|UniProtKB=W5M860 W5M860 PTHR10529:SF257 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;coated vesicle#GO:0030135;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007113.1|UniProtKB=W5MJQ7 W5MJQ7 PTHR22792:SF48 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006445.1|UniProtKB=W5MHC5 W5MHC5 PTHR13235:SF2 SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000007992.1|UniProtKB=W5MMU8 W5MMU8 PTHR24365:SF26 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 18 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009893.1|UniProtKB=W5MUN4 W5MUN4 TTC21A PTHR14699:SF2 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21A cilium organization#GO:0044782;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;plasma membrane bounded cell projection organization#GO:0120036;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 intraciliary transport particle A#GO:0030991;protein-containing complex#GO:0032991;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000010317.1|UniProtKB=W5MW90 W5MW90 PTHR43272:SF54 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 6 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004658.1|UniProtKB=W5MB75 W5MB75 PTHR13817:SF96 TITIN NEURAL CELL ADHESION MOLECULE 1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009866.1|UniProtKB=W5MUJ9 W5MUJ9 PTHR10218:SF364 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN (G PROTEIN), Q POLYPEPTIDE GTPase activity#GO:0003924;molecular function activator activity#GO:0140677;binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;ribonucleoside triphosphate phosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Endothelin signaling pathway#P00019>Gq#P00586;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gqalpha#P05927;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;PI3 kinase pathway#P00048>Galpha#P01199 LEPOC|Ensembl=ENSLOCG00000012999.1|UniProtKB=W5N5V0 W5N5V0 PTHR12665:SF11 ORMDL PROTEINS ORM1-LIKE PROTEIN 3 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;intracellular chemical homeostasis#GO:0055082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007012.1|UniProtKB=W5MJD0 W5MJD0 PTHR14389:SF3 SI:CH1073-475A24.1 PROTEIN FAM111A-LIKE LEPOC|Ensembl=ENSLOCG00000010303.1|UniProtKB=W5MW76 W5MW76 PTHR10653:SF5 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000001396.1|UniProtKB=W5LZT2 W5LZT2 LAMA3 PTHR10574:SF445 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA 3 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000009798.1|UniProtKB=W5MUD3 W5MUD3 PTHR42884:SF7 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000001546.1|UniProtKB=W5M061 W5M061 PTHR31171:SF0 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6 signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000016153.1|UniProtKB=W5NGZ6 W5NGZ6 PTHR45865:SF1 E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE SHPRH ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016193.1|UniProtKB=W5NH53 W5NH53 PTHR18919:SF107 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000015305.1|UniProtKB=W5NDX5 W5NDX5 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN US3M macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003544.1|UniProtKB=W5M730 W5M730 PTHR28498:SF1 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000001285.1|UniProtKB=W5LZ96 W5LZ96 PTHR12080:SF134 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006985.1|UniProtKB=W5MJ97 W5MJ97 PTHR22884:SF293 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD2 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008195.1|UniProtKB=W5MNJ0 W5MNJ0 PTHR15367:SF4 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7-LIKE nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000010249.1|UniProtKB=W5MVY4 W5MVY4 PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;Golgi organization#GO:0007030;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;membrane#GO:0016020;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000004425.1|UniProtKB=W5MA88 W5MA88 PTHR13140:SF802 MYOSIN UNCONVENTIONAL MYOSIN-IB ISOFORM X1 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 actin filament-based movement#GO:0030048;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000011058.1|UniProtKB=W5MYW7 W5MYW7 PTHR16484:SF4 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG B lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of cell polarity#GO:0030010;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;centrosome localization#GO:0051642;establishment of localization in cell#GO:0051649;establishment or maintenance of apical/basal cell polarity#GO:0035088;cytoskeleton organization#GO:0007010;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324 LEPOC|Ensembl=ENSLOCG00000002848.1|UniProtKB=W5M4P7 W5M4P7 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000832.1|UniProtKB=W5LXS0 W5LXS0 PTHR23266:SF390 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003285.1|UniProtKB=W5M687 W5M687 PTHR12610:SF22 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 3 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000017069.1|UniProtKB=W5NKD5 W5NKD5 PTHR31531:SF2 E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE E3D ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012553.1|UniProtKB=W5N4A6 W5N4A6 PTHR10217:SF630 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004535.1|UniProtKB=W5MAL7 W5MAL7 PTHR10615:SF73 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6B histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;N-acyltransferase activity#GO:0016410;molecular adaptor activity#GO:0060090;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 p53 pathway#P00059>CBP#P04623 LEPOC|Ensembl=ENSLOCG00000015522.1|UniProtKB=W5NEP3 W5NEP3 PTHR46544:SF2 EXTRACELLULAR MATRIX PROTEIN 2-RELATED EXTRACELLULAR MATRIX PROTEIN 2-RELATED collagen binding#GO:0005518;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;positive regulation of cell-substrate adhesion#GO:0010811;external encapsulating structure organization#GO:0045229;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular component organization#GO:0016043;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;extracellular matrix organization#GO:0030198;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cellular process#GO:0048522 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000001635.1|UniProtKB=W5M0H3 W5M0H3 PTHR18945:SF401 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotine pharmacodynamics pathway#P06587>CHRNA4#P06594;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000009876.1|UniProtKB=W5MUL4 W5MUL4 PTHR12566:SF8 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;synapse#GO:0045202;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010160.1|UniProtKB=W5MVM9 W5MVM9 PTHR20855:SF40 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 LEPOC|Ensembl=ENSLOCG00000014907.1|UniProtKB=W5NCK3 W5NCK3 PTHR11958:SF19 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER B(0) inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010038.1|UniProtKB=W5MV63 W5MV63 MDFIC2 PTHR15304:SF2 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000220.1|UniProtKB=W5LVT9 W5LVT9 PTHR12107:SF12 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-7 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;channel regulator activity#GO:0016247;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;system process#GO:0003008;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;receptor-mediated endocytosis#GO:0006898;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;protein localization to organelle#GO:0033365;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;positive regulation of biological process#GO:0048518;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;vacuolar transport#GO:0007034;endocytosis#GO:0006897;protein localization to vacuole#GO:0072665;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;positive regulation of synaptic transmission#GO:0050806;import into cell#GO:0098657;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007526.1|UniProtKB=W5ML70 W5ML70 PTHR31601:SF2 28S RIBOSOMAL PROTEIN S36, MITOCHONDRIAL ALPHA-KETOGLUTARATE DEHYDROGENASE COMPONENT 4 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;dicarboxylic acid metabolic process#GO:0043648;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017197.1|UniProtKB=W5NKU9 W5NKU9 PTHR11785:SF340 AMINO ACID TRANSPORTER AROMATIC-PREFERRING AMINO ACID TRANSPORTER L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015911.1|UniProtKB=W5NG33 W5NG33 PTHR21257:SF55 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE LBR oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016614.1|UniProtKB=W5NIR3 W5NIR3 PTHR31233:SF3 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 1 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;dynein complex binding#GO:0070840 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;regulation of endocytosis#GO:0030100;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular macromolecule localization#GO:0070727;regulation of transport#GO:0051049;microtubule-based process#GO:0007017;positive regulation of endocytosis#GO:0045807;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;positive regulation of biological process#GO:0048518;regulation of receptor-mediated endocytosis#GO:0048259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004027.1|UniProtKB=W5M8V8 W5M8V8 PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000017684.1|UniProtKB=W5NMD0 W5NMD0 PTHR40472:SF9 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 4 LEPOC|Ensembl=ENSLOCG00000006392.1|UniProtKB=W5MH63 W5MH63 PTHR10529:SF370 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;coated vesicle#GO:0030135;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012641.1|UniProtKB=W5N4J7 W5N4J7 BAK1 PTHR11256:SF41 BCL-2 RELATED BCL-2 HOMOLOGOUS ANTAGONIST_KILLER wide pore channel activity#GO:0022829;protein binding#GO:0005515;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bak#P00275 LEPOC|Ensembl=ENSLOCG00000000893.1|UniProtKB=W5LXY5 W5LXY5 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016815.1|UniProtKB=W5NJH2 W5NJH2 PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA protein binding#GO:0005515;protein kinase regulator activity#GO:0019887;binding#GO:0005488;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 LEPOC|Ensembl=ENSLOCG00000009329.1|UniProtKB=W5MSM1 W5MSM1 PTHR21324:SF13 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED SI:DKEY-228D14.5 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004465.1|UniProtKB=W5MAC7 W5MAC7 PTHR20922:SF13 DNL-TYPE ZINC FINGER PROTEIN DNL-TYPE ZINC FINGER PROTEIN protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein transmembrane import into intracellular organelle#GO:0044743;protein stabilization#GO:0050821;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;mitochondrial transmembrane transport#GO:1990542;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;mitochondrial transport#GO:0006839;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;protein folding#GO:0006457;protein transport#GO:0015031;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003527.1|UniProtKB=W5M737 W5M737 PTHR11584:SF363 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 15 MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016138.1|UniProtKB=W5NGX7 W5NGX7 PTHR11909:SF100 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011904.1|UniProtKB=W5N1Y0 W5N1Y0 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016941.1|UniProtKB=W5NJZ4 W5NJZ4 PTHR13902:SF46 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;molecular function inhibitor activity#GO:0140678;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of sodium ion transport#GO:0002028;macromolecule modification#GO:0043412;regulation of metal ion transport#GO:0010959;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of monoatomic ion transport#GO:0043269;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008322.1|UniProtKB=W5MP01 W5MP01 PTHR16294:SF5 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;organelle localization#GO:0051640;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;microtubule-based movement#GO:0007018;endomembrane system organization#GO:0010256;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;secretory granule organization#GO:0033363;regulation of vesicle-mediated transport#GO:0060627;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;establishment of vesicle localization#GO:0051650;regulation of secretion#GO:0051046;establishment of organelle localization#GO:0051656;regulation of exocytosis#GO:0017157;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;transport along microtubule#GO:0010970;negative regulation of nitrogen compound metabolic process#GO:0051172;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;regulation of catalytic activity#GO:0050790;system development#GO:0048731;axo-dendritic transport#GO:0008088;cell differentiation#GO:0030154;regulation of transport#GO:0051049;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;vesicle localization#GO:0051648;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;negative regulation of catalytic activity#GO:0043086;organelle transport along microtubule#GO:0072384;regulation of transferase activity#GO:0051338;vesicle cytoskeletal trafficking#GO:0099518;negative regulation of molecular function#GO:0044092 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013164.1|UniProtKB=W5N6G2 W5N6G2 PTHR44675:SF1 PAK1 INTERACTING PROTEIN 1 P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000004153.1|UniProtKB=W5M9B1 W5M9B1 PTHR11588:SF298 TUBULIN TUBULIN ALPHA-1C CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 LEPOC|Ensembl=ENSLOCG00000013946.1|UniProtKB=W5N979 W5N979 PTHR16244:SF2 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000007822.1|UniProtKB=W5MM88 W5MM88 LANCL3 PTHR12736:SF7 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006117.1|UniProtKB=W5MG87 W5MG87 PTHR24056:SF0 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002028.1|UniProtKB=W5M1U9 W5M1U9 PTHR45718:SF6 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLI2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cell communication#GO:0007154;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 LEPOC|Ensembl=ENSLOCG00000000941.1|UniProtKB=W5LY75 W5LY75 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 cell division#GO:0051301;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;developmental process#GO:0032502;multicellular organism development#GO:0007275;activation of GTPase activity#GO:0090630;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;nervous system development#GO:0007399;mitotic cell cycle process#GO:1903047;positive regulation of hydrolase activity#GO:0051345;system development#GO:0048731;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;anatomical structure development#GO:0048856;biological regulation#GO:0065007;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;regulation of hydrolase activity#GO:0051336;cytokinesis#GO:0000910 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000262.1|UniProtKB=W5LVZ7 W5LVZ7 PTHR33769:SF1 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 TESTIS-EXPRESSED PROTEIN 26 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014307.1|UniProtKB=W5NAH6 W5NAH6 PTHR11036:SF20 SEMAPHORIN SEMAPHORIN-3G molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000018295.1|UniProtKB=W5NP37 W5NP37 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004994.1|UniProtKB=W5MCA5 W5MCA5 PTHR46647:SF1 RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS LEPOC|Ensembl=ENSLOCG00000004237.1|UniProtKB=W5M9K8 W5M9K8 PTHR34769:SF1 RCG42593, ISOFORM CRA_A RNA POLYMERASE I AND III SUBUNIT D General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000000374.1|UniProtKB=W5LW98 W5LW98 PTHR46791:SF13 EXPRESSED PROTEIN CLR5 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004899.1|UniProtKB=W5MBX4 W5MBX4 PTHR24300:SF395 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008379.1|UniProtKB=W5MP73 W5MP73 PTHR16230:SF3 CAPPUCCINO BIOGENESIS OF LYSOSOMAL ORGANELLES COMPLEX-1, SUBUNIT 4, CAPPUCCINO intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000004020.1|UniProtKB=W5M8U2 W5M8U2 PTHR46639:SF2 DIENCEPHALON/MESENCEPHALON HOMEOBOX PROTEIN 1 DIENCEPHALON_MESENCEPHALON HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006304.1|UniProtKB=W5MGV3 W5MGV3 PTHR46440:SF2 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-C12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000008995.1|UniProtKB=W5MRG1 W5MRG1 PTHR11977:SF35 VILLIN VILLIN-1 cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cytoskeleton#GO:0005856;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000015727.1|UniProtKB=W5NFF3 W5NFF3 PTHR24056:SF128 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 17 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007985.1|UniProtKB=W5MMT5 W5MMT5 PTHR13593:SF33 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013645.1|UniProtKB=W5N865 W5N865 PTHR10188:SF6 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003430.1|UniProtKB=W5M6S1 W5M6S1 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005492.1|UniProtKB=W5ME41 W5ME41 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000017971.1|UniProtKB=W5NN63 W5NN63 PTHR23401:SF2 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209 neuron projection guidance#GO:0097485;head development#GO:0060322;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;distal axon#GO:0150034;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000012984.1|UniProtKB=W5N5T4 W5N5T4 PTHR21705:SF10 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 2A LEPOC|Ensembl=ENSLOCG00000007310.1|UniProtKB=W5MKE2 W5MKE2 PTHR15237:SF2 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9B DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;response to radiation#GO:0009314;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;cellular response to stress#GO:0033554;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000009361.1|UniProtKB=W5MSQ8 W5MSQ8 PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 LEPOC|Ensembl=ENSLOCG00000015376.1|UniProtKB=W5NE67 W5NE67 PTHR24223:SF173 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000001.1|UniProtKB=W5LV44 W5LV44 PTHR19300:SF33 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 3 galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;glycosylation#GO:0070085;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007493.1|UniProtKB=W5ML38 W5ML38 PTHR48230:SF1 FAMILY NOT NAMED LIPID DESATURASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002115.1|UniProtKB=W5M255 W5M255 PTHR11468:SF32 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, MUSCLE FORM transferase activity#GO:0016740;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 LEPOC|Ensembl=ENSLOCG00000016838.1|UniProtKB=W5NJK1 W5NJK1 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692 LEPOC|Ensembl=ENSLOCG00000009019.1|UniProtKB=W5MRI1 W5MRI1 PTHR15955:SF8 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2B-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009067.1|UniProtKB=W5MRP0 W5MRP0 PTHR13214:SF1 ZINC FINGER PROTEIN 330 ZINC FINGER PROTEIN 330 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006124.1|UniProtKB=W5MGC1 W5MGC1 PTHR46697:SF1 FORMIN-BINDING PROTEIN 4 FORMIN-BINDING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000003610.1|UniProtKB=W5M7C4 W5M7C4 PTHR10383:SF22 SERINE INCORPORATOR SERINE INCORPORATOR 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008286.1|UniProtKB=W5MNV5 W5MNV5 PTHR22591:SF1 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;actomyosin#GO:0042641;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000333.1|UniProtKB=W5LW57 W5LW57 PTHR11036:SF145 SEMAPHORIN SEMAPHORIN-4A ISOFORM X1-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014981.1|UniProtKB=W5NCT4 W5NCT4 PTHR14136:SF17 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 LEPOC|Ensembl=ENSLOCG00000014533.1|UniProtKB=W5NB79 W5NB79 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000009527.1|UniProtKB=W5MTE2 W5MTE2 PTHR12300:SF29 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996 supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;microtubule#GO:0005874;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010224.1|UniProtKB=W5MVX2 W5MVX2 PTHR46318:SF5 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 ISOFORM X1 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006197.1|UniProtKB=W5MGH5 W5MGH5 ASXL3 PTHR13578:SF18 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL3-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003622.1|UniProtKB=W5M7D7 W5M7D7 PTHR21668:SF0 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 4C nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017041.1|UniProtKB=W5NKA5 W5NKA5 PTHR46532:SF11 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 12 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000001128.1|UniProtKB=W5LYR3 W5LYR3 PTHR15491:SF16 FAMILY NOT NAMED ZINC FINGER PROTEIN 638 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007507.1|UniProtKB=W5ML59 W5ML59 PTHR45668:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 1 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005346.1|UniProtKB=W5MDJ1 W5MDJ1 PTHR46051:SF3 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 1 regulation of myeloid cell differentiation#GO:0045637;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of hemopoiesis#GO:1903706;regulation of signal transduction#GO:0009966;regulation of tissue remodeling#GO:0034103;regulation of immune system process#GO:0002682;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of leukocyte activation#GO:0002694;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of bone resorption#GO:0045124;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;positive regulation of cell activation#GO:0050867;regulation of bone remodeling#GO:0046850;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004293.1|UniProtKB=W5M9S2 W5M9S2 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017324.1|UniProtKB=W5NLC0 W5NLC0 PTHR11589:SF3 NERVE GROWTH FACTOR NGF -RELATED BRAIN-DERIVED NEUROTROPHIC FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;response to growth factor#GO:0070848;regulation of signaling#GO:0023051;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;generation of neurons#GO:0048699 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;extracellular region#GO:0005576;cell junction#GO:0030054;dendrite#GO:0030425;extracellular space#GO:0005615;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 Huntington disease#P00029>BDNF#G01531;Huntington disease#P00029>BDNF#P00795;Metabotropic glutamate receptor group II pathway#P00040>BDNF#G01540 LEPOC|Ensembl=ENSLOCG00000004452.1|UniProtKB=W5MAA6 W5MAA6 PTHR12623:SF11 NGFI-A BINDING PROTEIN PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1-LIKE molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017225.1|UniProtKB=W5NKZ4 W5NKZ4 PTHR22444:SF1 GLUTAMATE-RICH PROTEIN 1 GLUTAMATE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002691.1|UniProtKB=W5M452 W5M452 PTHR45828:SF36 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013240.1|UniProtKB=W5N6Q1 W5N6Q1 PTHR10603:SF3 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;RNA localization#GO:0006403;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;RNA transport#GO:0050658;regulation of neuronal synaptic plasticity#GO:0048168;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of multicellular organismal process#GO:0051239;establishment of RNA localization#GO:0051236;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;regulation of trans-synaptic signaling#GO:0099177;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule localization#GO:0033036;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;regulation of amide metabolic process#GO:0034248;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;nucleic acid transport#GO:0050657;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cell communication#GO:0010646;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;regulation of cellular catabolic process#GO:0031329;mRNA transport#GO:0051028;positive regulation of developmental process#GO:0051094;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cell projection#GO:0042995 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000013835.1|UniProtKB=W5N8V1 W5N8V1 PTHR47979:SF110 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;protein-containing complex localization#GO:0031503 synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;postsynapse#GO:0098794 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002079.1|UniProtKB=W5M204 W5M204 PTHR24064:SF198 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 13 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013721.1|UniProtKB=W5N8G1 W5N8G1 PTHR16155:SF3 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002265.1|UniProtKB=W5M2Q9 W5M2Q9 PTHR46303:SF3 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005646.1|UniProtKB=W5MEL1 W5MEL1 PTHR10270:SF216 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-17 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;negative regulation of signaling#GO:0023057;tube development#GO:0035295;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;heart development#GO:0007507;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;system development#GO:0048731;endoderm formation#GO:0001706;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;vasculogenesis#GO:0001570;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of DNA-templated transcription#GO:0045893;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of RNA metabolic process#GO:0051254;embryonic morphogenesis#GO:0048598 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000005722.1|UniProtKB=W5MEU6 W5MEU6 PTHR45964:SF8 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 1 LEPOC|Ensembl=ENSLOCG00000011426.1|UniProtKB=W5N086 W5N086 PTHR46121:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STARD3 N-TERMINAL-LIKE PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;sterol transport#GO:0015918;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;lipid localization#GO:0010876;establishment of organelle localization#GO:0051656 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;organelle membrane contact site#GO:0044232;vesicle#GO:0031982;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;lysosome#GO:0005764;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuolar membrane#GO:0005774;organelle subcompartment#GO:0031984;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000005794.1|UniProtKB=W5MF40 W5MF40 PTHR23226:SF248 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 648 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006186.1|UniProtKB=W5MGG9 W5MGG9 PTHR10190:SF7 EYES ABSENT EYES ABSENT HOMOLOG 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of DNA repair#GO:0045739;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of DNA repair#GO:0006282;regulation of biological process#GO:0050789;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of response to stress#GO:0080134;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000008999.1|UniProtKB=W5MRF0 W5MRF0 PTHR15454:SF71 NISCHARIN RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008306.1|UniProtKB=W5MNY2 W5MNY2 PTHR24381:SF390 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 37 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012357.1|UniProtKB=W5N3L1 W5N3L1 PTHR14791:SF22 BOMB/KIRA PROTEINS PROTEIN KIBRA enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;cell motility#GO:0048870;regulation of RNA biosynthetic process#GO:2001141;regulation of growth#GO:0040008;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell migration#GO:0016477;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012022.1|UniProtKB=W5N2C8 W5N2C8 PTHR24020:SF37 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 2 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000001536.1|UniProtKB=W5M046 W5M046 PTHR31171:SF3 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6B signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000008566.1|UniProtKB=W5MPW2 W5MPW2 PTHR15717:SF2 PROTEIN KIAA0494 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 14 LEPOC|Ensembl=ENSLOCG00000001954.1|UniProtKB=W5M1L7 W5M1L7 PTHR11576:SF16 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000009801.1|UniProtKB=W5MUB5 W5MUB5 PTHR13738:SF9 TROPONIN I TROPONIN I, SLOW SKELETAL MUSCLE blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007913.1|UniProtKB=W5MMK3 W5MMK3 PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA sequence-specific DNA binding#GO:0043565;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005406.1|UniProtKB=W5MDR1 W5MDR1 PTHR12315:SF1 BICOID-INTERACTING PROTEIN RELATED RNA 5'-MONOPHOSPHATE METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011522.1|UniProtKB=W5N0K4 W5N0K4 PTHR10336:SF33 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-3 lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000013959.1|UniProtKB=W5N996 W5N996 PTHR47915:SF1 SI:DKEY-19B23.7 SI:DKEY-19B23.7 LEPOC|Ensembl=ENSLOCG00000003510.1|UniProtKB=W5M706 W5M706 PTHR24046:SF3 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006456.1|UniProtKB=W5MHE1 W5MHE1 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002800.1|UniProtKB=W5M4J0 W5M4J0 PTHR12924:SF1 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007050.1|UniProtKB=W5MJI8 W5MJI8 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000014990.1|UniProtKB=W5NCV0 W5NCV0 PTHR21564:SF2 BRAKELESS PROTEIN ZINC FINGER PROTEIN 609 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015483.1|UniProtKB=W5NEJ6 W5NEJ6 PTHR12489:SF13 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 3 PROTEIN multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;sensory perception of sound#GO:0007605;system process#GO:0003008 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001367.1|UniProtKB=W5LZJ8 W5LZJ8 FZR1 PTHR19918:SF34 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008274.1|UniProtKB=W5MNV7 W5MNV7 PTHR45920:SF2 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016151.1|UniProtKB=W5NGZ4 W5NGZ4 PTHR13428:SF10 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN INNER NUCLEAR MEMBRANE PROTEIN MAN1 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;membrane organization#GO:0061024;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular component organization or biogenesis#GO:0071840;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;nuclear envelope organization#GO:0006998;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000003247.1|UniProtKB=W5M635 W5M635 PTHR11616:SF306 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013174.1|UniProtKB=W5N6H5 W5N6H5 PTHR14130:SF13 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 44 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 endosomal transport#GO:0016197;cellular localization#GO:0051641;nitrogen compound transport#GO:0071705;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;negative regulation of cell communication#GO:0010648;protein localization to synapse#GO:0035418;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;vesicle-mediated transport#GO:0016192;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;protein localization#GO:0008104;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;regulation of cell projection organization#GO:0031344;negative regulation of signal transduction#GO:0009968;regulation of synapse structure or activity#GO:0050803;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;transport#GO:0006810;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of small GTPase mediated signal transduction#GO:0051058;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of postsynapse organization#GO:0099175;protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;negative regulation of response to stimulus#GO:0048585;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization to cell periphery#GO:1990778;localization#GO:0051179;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;presynaptic active zone#GO:0048786;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008117.1|UniProtKB=W5MN98 W5MN98 PTHR24409:SF324 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 131 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010427.1|UniProtKB=W5MWM9 W5MWM9 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000000689.1|UniProtKB=W5LXB0 W5LXB0 PTHR11690:SF13 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007066.1|UniProtKB=W5MJJ6 W5MJJ6 PTHR22802:SF404 C-TYPE LECTIN SUPERFAMILY MEMBER SI:DKEY-9I23.4-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002326.1|UniProtKB=W5M2Y0 W5M2Y0 PTHR45745:SF2 PHOSPHOMANNOMUTASE 45A GLUCOSE 1,6-BISPHOSPHATE SYNTHASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;isomerase activity#GO:0016853;phosphotransferase activity, alcohol group as acceptor#GO:0016773;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;purine-containing compound biosynthetic process#GO:0072522;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;glycosyl compound metabolic process#GO:1901657;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000008332.1|UniProtKB=W5MP11 W5MP11 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007993.1|UniProtKB=W5MMV7 W5MMV7 PTHR13351:SF1 RENIN RECEPTOR RENIN RECEPTOR external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001483.1|UniProtKB=W5LZZ2 W5LZZ2 PTHR22590:SF3 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN IQ DOMAIN-CONTAINING PROTEIN E LEPOC|Ensembl=ENSLOCG00000012519.1|UniProtKB=W5N454 W5N454 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 3A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004439.1|UniProtKB=W5MAD1 W5MAD1 PTHR45728:SF1 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 2 ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014597.1|UniProtKB=W5NBF2 W5NBF2 PTHR12547:SF157 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000252.1|UniProtKB=W5LVW9 W5LVW9 PTHR24388:SF99 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF52.1-LIKE ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018179.1|UniProtKB=W5NNS1 W5NNS1 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003940.1|UniProtKB=W5M8J6 W5M8J6 PTHR45655:SF15 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000003587.1|UniProtKB=W5M7B3 W5M7B3 ABR PTHR23182:SF5 BREAKPOINT CLUSTER REGION PROTEIN BCR ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009977.1|UniProtKB=W5MUY8 W5MUY8 PTHR47410:SF2 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;activation of immune response#GO:0002253;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;canonical NF-kappaB signal transduction#GO:0007249;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;positive regulation of macromolecule metabolic process#GO:0010604;defense response to symbiont#GO:0140546;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;signal transduction#GO:0007165;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cytokine production#GO:0001817;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000009885.1|UniProtKB=W5MUM4 W5MUM4 PTHR43247:SF1 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058;Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157 LEPOC|Ensembl=ENSLOCG00000004087.1|UniProtKB=W5M921 W5M921 PTHR16470:SF0 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 cell adhesion molecule binding#GO:0050839;nucleic acid binding#GO:0003676;protein binding#GO:0005515;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 LEPOC|Ensembl=ENSLOCG00000009140.1|UniProtKB=W5MRZ5 W5MRZ5 PTHR47633:SF4 IMMUNOGLOBULIN MYOPALLADIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000011294.1|UniProtKB=W5MZS4 W5MZS4 PTHR33662:SF3 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED FIBROUS SHEATH CABYR-BINDING PROTEIN-LIKE-RELATED cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010722.1|UniProtKB=W5MXM9 W5MXM9 PTHR11534:SF5 MYOGENIC FACTOR MYOGENIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;muscle organ development#GO:0007517;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;muscle tissue development#GO:0060537;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014326.1|UniProtKB=W5NAI2 W5NAI2 PTHR11471:SF28 TUMOR NECROSIS FACTOR FAMILY MEMBER DEATH LIGAND 1B-RELATED intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003607.1|UniProtKB=W5M7C5 W5M7C5 PTHR24027:SF78 CADHERIN-23 CADHERIN-LIKE PROTEIN 26 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000013408.1|UniProtKB=W5N7D1 W5N7D1 PTHR43157:SF27 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 12, LIKE glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005106.1|UniProtKB=W5MCN8 W5MCN8 SESN2 PTHR12474:SF2 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-2 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of metabolic process#GO:0009893;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;positive regulation of macroautophagy#GO:0016239;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005621.1|UniProtKB=W5MEH6 W5MEH6 PTHR12035:SF135 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 13 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010293.1|UniProtKB=W5MW52 W5MW52 PTHR23122:SF34 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 4 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009311.1|UniProtKB=W5MSJ7 W5MSJ7 PTHR15746:SF14 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 5 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;secretory vesicle#GO:0099503 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017913.1|UniProtKB=W5NN07 W5NN07 PTHR16083:SF8 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular developmental process#GO:0048869;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009915.1|UniProtKB=W5MUR2 W5MUR2 PTHR16172:SF2 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003984.1|UniProtKB=W5M8P8 W5M8P8 PTHR24393:SF60 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 16 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005779.1|UniProtKB=W5MF24 W5MF24 PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 LEPOC|Ensembl=ENSLOCG00000008519.1|UniProtKB=W5MPR2 W5MPR2 PTHR13526:SF8 TRANSCRIPTION FACTOR SPT20 HOMOLOG TRANSCRIPTION FACTOR SPT20 HOMOLOG molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010333.1|UniProtKB=W5MWA8 W5MWA8 RANBP2 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000856.1|UniProtKB=W5LXU6 W5LXU6 PTHR40240:SF1 PLEXUS, ISOFORM A PLEXUS, ISOFORM A LEPOC|Ensembl=ENSLOCG00000008511.1|UniProtKB=W5MPP8 W5MPP8 PTHR45691:SF18 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000000002.1|UniProtKB=W5LV45 W5LV45 PTHR31594:SF15 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN VERRUCOTOXIN SUBUNIT BETA ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000002634.1|UniProtKB=W5M3Y4 W5M3Y4 PTHR11003:SF59 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017651.1|UniProtKB=W5NM97 W5NM97 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006773.1|UniProtKB=W5MIH3 W5MIH3 PTHR23189:SF6 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 2 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002523.1|UniProtKB=W5M3K1 W5M3K1 PTHR12372:SF4 PECANEX PECANEX-LIKE PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000011457.1|UniProtKB=W5N0B7 W5N0B7 PTHR24403:SF102 ZINC FINGER PROTEIN RE1-SILENCING TRANSCRIPTION FACTOR positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010242.1|UniProtKB=W5MW17 W5MW17 SYNE2 PTHR14514:SF4 PKA ANCHORING PROTEIN NESPRIN-2 LEPOC|Ensembl=ENSLOCG00000015243.1|UniProtKB=W5NDP7 W5NDP7 PTHR24394:SF58 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN CONTAINING 33 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001509.1|UniProtKB=W5M011 W5M011 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003696.1|UniProtKB=W5M7N8 W5M7N8 PTHR30336:SF20 INNER MEMBRANE PROTEIN, PROBABLE PERMEASE DUF218 DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012002.1|UniProtKB=W5N299 W5N299 PTHR10671:SF85 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000014316.1|UniProtKB=W5NAG9 W5NAG9 PTHR13622:SF8 THIAMIN PYROPHOSPHOKINASE THIAMIN PYROPHOSPHOKINASE 1 kinase#PC00137 Thiamin metabolism#P02780>Thiamine kinase#P03176 LEPOC|Ensembl=ENSLOCG00000006288.1|UniProtKB=W5MGT7 W5MGT7 PTHR14969:SF17 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE INACTIVE PHOSPHOLIPID PHOSPHATASE 7 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009233.1|UniProtKB=W5MSA0 W5MSA0 PTHR19305:SF1 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 47 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000007733.1|UniProtKB=W5MLY0 W5MLY0 PTHR13495:SF0 NEFA-INTERACTING NUCLEAR PROTEIN NIP30 PSME3-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013576.1|UniProtKB=W5N7Z2 W5N7Z2 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 neutral amino acid transport#GO:0015804;quaternary ammonium group transport#GO:0015697;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;organic cation transport#GO:0015695;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003331.1|UniProtKB=W5M6K9 W5M6K9 PTHR46877:SF11 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000008954.1|UniProtKB=W5MR97 W5MR97 STON2 PTHR10529:SF345 AP COMPLEX SUBUNIT MU STONIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;regulation of endocytosis#GO:0030100;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;synaptic vesicle recycling#GO:0036465;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endocytic vesicle#GO:0030139;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008698.1|UniProtKB=W5MQD3 W5MQD3 PTHR13271:SF47 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014158.1|UniProtKB=W5N9Y2 W5N9Y2 PTHR13723:SF310 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE 5 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012337.1|UniProtKB=W5N3H9 W5N3H9 PTHR46624:SF3 AGAP002036-PA ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1 phosphatidylinositol-3-phosphate binding#GO:0032266;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;maintenance of location#GO:0051235;organelle organization#GO:0006996;cellular component organization#GO:0016043;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular process#GO:0009987;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009891.1|UniProtKB=W5MUN5 W5MUN5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015826.1|UniProtKB=W5NFS4 W5NFS4 PTHR21642:SF4 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN cellular developmental process#GO:0048869;heart development#GO:0007507;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;cellular process#GO:0009987;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501;vasculogenesis#GO:0001570 EGF receptor signaling pathway#P00018>MEKK1-5#P00553 LEPOC|Ensembl=ENSLOCG00000016092.1|UniProtKB=W5NGS0 W5NGS0 PTHR13817:SF101 TITIN PROTEIN TURTLE HOMOLOG A-LIKE structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000000473.1|UniProtKB=W5LWL2 W5LWL2 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002126.1|UniProtKB=W5M268 W5M268 PTHR13423:SF2 OUT AT FIRST OUT AT FIRST PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000003177.1|UniProtKB=W5M5Y4 W5M5Y4 PTHR24023:SF987 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000012329.1|UniProtKB=W5N3G3 W5N3G3 PTHR24072:SF144 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOV GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000012368.1|UniProtKB=W5N3L3 W5N3L3 PTHR44252:SF3 D-ERYTHRULOSE REDUCTASE D-ERYTHRULOSE REDUCTASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002108.1|UniProtKB=W5M259 W5M259 PTHR11640:SF161 NEPHRIN HEMICENTIN-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005370.1|UniProtKB=W5MDL0 W5MDL0 PTHR22791:SF31 RING-TYPE DOMAIN-CONTAINING PROTEIN IM:7152348 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016806.1|UniProtKB=W5NJG4 W5NJG4 PTHR22599:SF48 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000011997.1|UniProtKB=W5N2A3 W5N2A3 PTHR12106:SF8 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013542.1|UniProtKB=W5N7U3 W5N7U3 CEP95 PTHR22545:SF0 CENTROSOMAL PROTEIN OF 95 KDA CENTROSOMAL PROTEIN OF 95 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017077.1|UniProtKB=W5NKE4 W5NKE4 PTHR22738:SF8 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001982.1|UniProtKB=W5M1N4 W5M1N4 PTHR10334:SF62 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR R3HDML extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007776.1|UniProtKB=W5MM36 W5MM36 PTHR32546:SF11 G-PROTEIN COUPLED RECEPTOR 158-RELATED G-PROTEIN COUPLED RECEPTOR 158-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008225.1|UniProtKB=W5MNM6 W5MNM6 PTHR24404:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PEGASUS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016658.1|UniProtKB=W5NIW9 W5NIW9 PTHR11482:SF42 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053;CCKR signaling map#P06959>ODC1#P07221;CCKR signaling map#P06959>ODC1#G06989 LEPOC|Ensembl=ENSLOCG00000016303.1|UniProtKB=W5NHL3 W5NHL3 PTHR14063:SF4 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG A protein binding#GO:0005515;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 membrane protein complex#GO:0098796;synapse#GO:0045202;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal plasma membrane#GO:0009925;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;adherens junction#GO:0005912;basal part of cell#GO:0045178;plasma membrane#GO:0005886 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000001463.1|UniProtKB=W5LZW6 W5LZW6 PTHR45640:SF27 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-2 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 negative regulation of biological process#GO:0048519;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;protein folding#GO:0006457;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000016351.1|UniProtKB=W5NHU0 W5NHU0 PTHR24351:SF182 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C EPSILON TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PKC#P00565;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 LEPOC|Ensembl=ENSLOCG00000005338.1|UniProtKB=W5MDH7 W5MDH7 PTHR45716:SF5 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003775.1|UniProtKB=W5M7Z1 W5M7Z1 PTHR14132:SF12 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA PHOSPHOLEMMAN transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transporter activity#GO:0032409 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000896.1|UniProtKB=W5LY05 W5LY05 PTHR22826:SF201 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR MCF2L2-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014480.1|UniProtKB=W5NB13 W5NB13 PTHR15275:SF0 CG1 PROTEIN/F18 MASTERMIND-LIKE DOMAIN-CONTAINING PROTEIN 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008193.1|UniProtKB=W5MNI5 W5MNI5 PTHR22698:SF1 PDZ DOMAIN-CONTAINING PROTEIN 9 PDZ DOMAIN-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000006364.1|UniProtKB=W5MH19 W5MH19 PSPN PTHR12173:SF11 GDNF SUBFAMILY OF TGF-BETA FAMILY PERSEPHIN-LIKE molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neurotrophic factor#PC00163;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000016260.1|UniProtKB=W5NHE6 W5NHE6 PTHR31918:SF1 TRANSMEMBRANE PROTEIN 181 TRANSMEMBRANE PROTEIN 181 LEPOC|Ensembl=ENSLOCG00000012006.1|UniProtKB=W5N2B4 W5N2B4 PTHR12352:SF3 SECRETED MODULAR CALCIUM-BINDING PROTEIN NIDOGEN-2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010708.1|UniProtKB=W5MXL4 W5MXL4 PTHR42753:SF9 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN ML39 catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015136.1|UniProtKB=W5NDB8 W5NDB8 IKBIP PTHR21734:SF11 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000014113.1|UniProtKB=W5N9T3 W5N9T3 PTHR24006:SF714 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 46 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016388.1|UniProtKB=W5NHY1 W5NHY1 PTHR45712:SF6 AGAP008170-PA LUMICAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000001193.1|UniProtKB=W5LZ15 W5LZ15 PTHR45845:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED RIKEN CDNA D630003M21 GENE guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004321.1|UniProtKB=W5M9V0 W5M9V0 PTHR24253:SF81 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 9 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017016.1|UniProtKB=W5NK72 W5NK72 PTHR11208:SF34 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 2 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005536.1|UniProtKB=W5ME74 W5ME74 PTHR24248:SF142 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000009452.1|UniProtKB=W5MT29 W5MT29 PTHR23068:SF4 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2A protein binding#GO:0005515;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000002283.1|UniProtKB=W5M2Q7 W5M2Q7 PTHR31367:SF3 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;adenosine metabolic process#GO:0046085;purine-containing compound metabolic process#GO:0072521;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003169.1|UniProtKB=W5M5T5 W5M5T5 PTHR20920:SF4 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000851.1|UniProtKB=W5LXT6 W5LXT6 PTHR13557:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008336.1|UniProtKB=W5MP15 W5MP15 PTHR46843:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 16 BTB_POZ DOMAIN-CONTAINING PROTEIN 16 LEPOC|Ensembl=ENSLOCG00000015433.1|UniProtKB=W5NEF0 W5NEF0 PTHR46961:SF13 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 3 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006121.1|UniProtKB=W5MG89 W5MG89 PTHR45618:SF57 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED UCP2L PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to stress#GO:0006950;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007175.1|UniProtKB=W5MJY1 W5MJY1 PTHR23420:SF0 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006795.1|UniProtKB=W5MIM8 W5MIM8 PTHR14042:SF23 DOPEY-RELATED PROTEIN DOPEY-2 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000003516.1|UniProtKB=W5M709 W5M709 PTHR12066:SF0 TELOMERASE REVERSE TRANSCRIPTASE TELOMERASE REVERSE TRANSCRIPTASE sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 telomere maintenance via telomere lengthening#GO:0010833;cellular aromatic compound metabolic process#GO:0006725;telomere organization#GO:0032200;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;telomere maintenance via telomerase#GO:0007004;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;chromosome organization#GO:0051276;organelle organization#GO:0006996;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016603.1|UniProtKB=W5NIP8 W5NIP8 PTHR45963:SF1 RE52028P SORTING NEXIN-3 phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000004216.1|UniProtKB=W5M9K2 W5M9K2 PTHR11034:SF20 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010644.1|UniProtKB=W5MXC2 W5MXC2 VASH1 PTHR15750:SF5 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 1 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of anatomical structure morphogenesis#GO:0022603;biological regulation#GO:0065007;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013282.1|UniProtKB=W5N6V4 W5N6V4 BOLA2 PTHR12735:SF27 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000767.1|UniProtKB=W5LXJ2 W5LXJ2 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007069.1|UniProtKB=W5MJJ8 W5MJJ8 PTHR23036:SF16 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009511.1|UniProtKB=W5MTB7 W5MTB7 PTHR28629:SF4 TRIOKINASE/FMN CYCLASE TRIOKINASE_FMN CYCLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;alcohol metabolic process#GO:0006066;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cyclase#PC00079;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000015780.1|UniProtKB=W5NFL9 W5NFL9 PTHR24115:SF421 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF25 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016899.1|UniProtKB=W5NJT0 W5NJT0 PTHR10510:SF15 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A2, MITOCHONDRIAL regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001608.1|UniProtKB=W5M0F5 W5M0F5 PTHR16266:SF26 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 regulation of anatomical structure morphogenesis#GO:0022603;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cell shape#GO:0008360;regulation of cellular biosynthetic process#GO:0031326;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009947.1|UniProtKB=W5MUV6 W5MUV6 PTHR12623:SF9 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 1 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 LEPOC|Ensembl=ENSLOCG00000017406.1|UniProtKB=W5NLK2 W5NLK2 PTHR24228:SF11 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-1 ANGIOTENSIN II RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;defense response#GO:0006952;signaling#GO:0023052;inflammatory response#GO:0006954 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AT1-R#P05924 LEPOC|Ensembl=ENSLOCG00000006306.1|UniProtKB=W5MGW4 W5MGW4 ARHGEF17 PTHR12877:SF15 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000002588.1|UniProtKB=W5M3W9 W5M3W9 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003431.1|UniProtKB=W5M6Q4 W5M6Q4 PTHR10654:SF19 CAS SCAFFOLDING PROTEIN CAS SCAFFOLDING PROTEIN FAMILY MEMBER 4 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006449.1|UniProtKB=W5MHE5 W5MHE5 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000003201.1|UniProtKB=W5M5X6 W5M5X6 PTHR25465:SF32 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016933.1|UniProtKB=W5NK45 W5NK45 DST PTHR23169:SF24 ENVOPLAKIN DYSTONIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;wound healing#GO:0042060;cellular component organization#GO:0016043;cellular process#GO:0009987;response to stimulus#GO:0050896;cell-substrate junction assembly#GO:0007044;cellular component organization or biogenesis#GO:0071840;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;cell junction assembly#GO:0034329;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000013841.1|UniProtKB=W5N8W4 W5N8W4 PTHR11255:SF118 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE EPSILON transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013986.1|UniProtKB=W5N9D0 W5N9D0 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001613.1|UniProtKB=W5M0I6 W5M0I6 PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;regulation of cellular catabolic process#GO:0031329;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000006512.1|UniProtKB=W5MHL6 W5MHL6 PTHR23220:SF78 INTEGRIN ALPHA INTEGRIN ALPHA-4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000006810.1|UniProtKB=W5MIL3 W5MIL3 PTHR12011:SF454 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G5-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018303.1|UniProtKB=W5NP45 W5NP45 PTHR21428:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008032.1|UniProtKB=W5MMZ9 W5MMZ9 PTHR48407:SF1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003636.1|UniProtKB=W5M7F6 W5M7F6 PTHR45810:SF12 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002979.1|UniProtKB=W5M560 W5M560 PTHR10177:SF444 CYCLINS CYCLIN-A2 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 LEPOC|Ensembl=ENSLOCG00000000951.1|UniProtKB=W5LY50 W5LY50 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009530.1|UniProtKB=W5MTD9 W5MTD9 PTHR16523:SF6 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001205.1|UniProtKB=W5LZ39 W5LZ39 PTHR10314:SF194 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lyase#PC00144 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 LEPOC|Ensembl=ENSLOCG00000000622.1|UniProtKB=W5LX31 W5LX31 RNF224 PTHR47454:SF1 RING FINGER PROTEIN 224 RING FINGER PROTEIN 224 LEPOC|Ensembl=ENSLOCG00000010672.1|UniProtKB=W5MXH1 W5MXH1 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 small-subunit processome#GO:0032040;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000003584.1|UniProtKB=W5M795 W5M795 PTHR21740:SF3 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5-LIKE cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule depolymerization#GO:0007019;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013412.1|UniProtKB=W5N7D4 W5N7D4 PTHR15083:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014830.1|UniProtKB=W5NCA3 W5NCA3 PTHR45589:SF2 WD REPEAT DOMAIN 62, ISOFORM G WD REPEAT DOMAIN 62 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;centriole assembly#GO:0098534;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013678.1|UniProtKB=W5N8A4 W5N8A4 PTHR11086:SF18 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014861.1|UniProtKB=W5NCE8 W5NCE8 PTHR16092:SF14 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 ISOFORM X1 phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000002878.1|UniProtKB=W5M4T1 W5M4T1 PTHR11380:SF5 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000004410.1|UniProtKB=W5MA61 W5MA61 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007430.1|UniProtKB=W5MKY0 W5MKY0 PTHR45627:SF11 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 6 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 LEPOC|Ensembl=ENSLOCG00000003586.1|UniProtKB=W5M798 W5M798 PTHR10104:SF5 STATHMIN STATHMIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 LEPOC|Ensembl=ENSLOCG00000003111.1|UniProtKB=W5M5L6 W5M5L6 PTHR22028:SF5 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 191 LEPOC|Ensembl=ENSLOCG00000003757.1|UniProtKB=W5M7X1 W5M7X1 FAM135B PTHR12482:SF3 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135B lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000003714.1|UniProtKB=W5M7R8 W5M7R8 PTHR10804:SF11 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004169.1|UniProtKB=W5M9D4 W5M9D4 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000003974.1|UniProtKB=W5M8N5 W5M8N5 ZNF516 PTHR45925:SF3 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 516 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006216.1|UniProtKB=W5MGK2 W5MGK2 PTHR12011:SF216 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004828.1|UniProtKB=W5MBQ8 W5MBQ8 PTHR24012:SF717 RNA BINDING PROTEIN U4_U6 SNRNA-ASSOCIATED-SPLICING FACTOR PRP24 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015239.1|UniProtKB=W5NDP3 W5NDP3 PTHR45828:SF32 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SI:DKEY-251I10.2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017858.1|UniProtKB=W5NMV2 W5NMV2 PTHR24377:SF1020 IP01015P-RELATED GASTRULA ZINC FINGER PROTEIN XLCGF28.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008843.1|UniProtKB=W5MQV4 W5MQV4 NHLRC3 PTHR24104:SF31 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED NHL REPEAT-CONTAINING PROTEIN 3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 LEPOC|Ensembl=ENSLOCG00000003410.1|UniProtKB=W5M6P1 W5M6P1 PTHR10915:SF6 SYNDECAN SYNDECAN-2 cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016952.1|UniProtKB=W5NJZ7 W5NJZ7 PTHR46105:SF8 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007406.1|UniProtKB=W5MKT2 W5MKT2 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000012405.1|UniProtKB=W5N3R5 W5N3R5 PTHR11280:SF9 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE ISOMERASE 2 identical protein binding#GO:0042802;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;protein binding#GO:0005515;deaminase activity#GO:0019239;binding#GO:0005488;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;amino sugar catabolic process#GO:0046348;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;amide metabolic process#GO:0043603;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 LEPOC|Ensembl=ENSLOCG00000008357.1|UniProtKB=W5MP59 W5MP59 PTHR20855:SF39 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR DELTA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010418.1|UniProtKB=W5MWL5 W5MWL5 C3orf14 PTHR14286:SF2 GENE, 49355-RELATED CENTROSOMAL PROTEIN 15 KDA LEPOC|Ensembl=ENSLOCG00000020984.1|UniProtKB=W5NPB5 W5NPB5 PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899 LEPOC|Ensembl=ENSLOCG00000006299.1|UniProtKB=W5MGU9 W5MGU9 PTHR17615:SF7 PROTEIN FAM189A PROTEIN ENTREP3 LEPOC|Ensembl=ENSLOCG00000016577.1|UniProtKB=W5NIM1 W5NIM1 KMO PTHR46028:SF2 KYNURENINE 3-MONOOXYGENASE KYNURENINE 3-MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008232.1|UniProtKB=W5MNN5 W5MNN5 PTHR45710:SF31 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013347.1|UniProtKB=W5N739 W5N739 PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000007609.1|UniProtKB=W5MLI1 W5MLI1 PTHR24255:SF29 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT COMPONENT 1, S SUBCOMPONENT hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016925.1|UniProtKB=W5NJW2 W5NJW2 PTHR11937:SF487 ACTIN ACTIN-LIKE PROTEIN 6A protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular protein-containing complex#GO:0140535;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007373.1|UniProtKB=W5MKN0 W5MKN0 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 LEPOC|Ensembl=ENSLOCG00000015208.1|UniProtKB=W5NDK5 W5NDK5 PTHR19308:SF8 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 7, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000004063.1|UniProtKB=W5M8Z4 W5M8Z4 PTHR11722:SF0 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011844.1|UniProtKB=W5N1Q6 W5N1Q6 PTHR13382:SF10 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B ATP SYNTHASE SUBUNIT S, MITOCHONDRIAL cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015405.1|UniProtKB=W5NEA1 W5NEA1 PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011940.1|UniProtKB=W5N229 W5N229 PTHR24070:SF174 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of exocytosis#GO:0017157 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Ral#P04550 LEPOC|Ensembl=ENSLOCG00000011103.1|UniProtKB=W5MZ31 W5MZ31 PTHR13044:SF2 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000008240.1|UniProtKB=W5MNP9 W5MNP9 PTHR14167:SF31 SH3 DOMAIN-CONTAINING NOSTRIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000593.1|UniProtKB=W5LX17 W5LX17 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012424.1|UniProtKB=W5N3T8 W5N3T8 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000016152.1|UniProtKB=W5NGZ5 W5NGZ5 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000018266.1|UniProtKB=W5NP08 W5NP08 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003848.1|UniProtKB=W5M883 W5M883 PTHR46534:SF2 IGGFC_BINDING DOMAIN-CONTAINING PROTEIN VWFD DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000053.1|UniProtKB=W5LVA4 W5LVA4 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008350.1|UniProtKB=W5MP30 W5MP30 PTHR15297:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009266.1|UniProtKB=W5MSE5 W5MSE5 PTHR13774:SF17 PHENAZINE BIOSYNTHESIS PROTEIN PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN isomerase activity#GO:0016853;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015349.1|UniProtKB=W5NE31 W5NE31 PTHR11849:SF156 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000013114.1|UniProtKB=W5N694 W5N694 PTHR36960:SF1 SI:DKEY-32E6.3 SI:DKEY-32E6.3 LEPOC|Ensembl=ENSLOCG00000011799.1|UniProtKB=W5N1K4 W5N1K4 PTHR19879:SF4 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000009484.1|UniProtKB=W5MT73 W5MT73 PTHR15967:SF0 E2F-ASSOCIATED PHOSPHOPROTEIN E2F-ASSOCIATED PHOSPHOPROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002562.1|UniProtKB=W5M3P8 W5M3P8 PTHR26450:SF429 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006835.1|UniProtKB=W5MIQ6 W5MIQ6 PTHR11304:SF5 EPHRIN EPHRIN-A3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013662.1|UniProtKB=W5N884 W5N884 PTHR15601:SF15 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009594.1|UniProtKB=W5MTL4 W5MTL4 PTHR10269:SF15 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008207.1|UniProtKB=W5MNM1 W5MNM1 PTHR12570:SF1 FAMILY NOT NAMED MAGNESIUM TRANSPORTER NIPA2 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003999.1|UniProtKB=W5M8T1 W5M8T1 PTHR23042:SF52 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Circadian clock system#P00015>BMAL1#P00506;Circadian clock system#P00015>bmal1#G01500;Circadian clock system#P00015>bmal1#G01504;Hypoxia response via HIF activation#P00030>HIF-1beta#P00820 LEPOC|Ensembl=ENSLOCG00000009050.1|UniProtKB=W5MRL4 W5MRL4 PTHR24340:SF32 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006139.1|UniProtKB=W5MGB0 W5MGB0 PTHR46222:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP14 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014246.1|UniProtKB=W5NA85 W5NA85 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000006185.1|UniProtKB=W5MGG5 W5MGG5 PTHR42908:SF29 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2B-RELATED GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;ribosome binding#GO:0043022;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000017263.1|UniProtKB=W5NL43 W5NL43 PTHR13084:SF3 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 2 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959 LEPOC|Ensembl=ENSLOCG00000016496.1|UniProtKB=W5NIB5 W5NIB5 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005852.1|UniProtKB=W5MFA5 W5MFA5 PTHR23277:SF69 NECTIN-RELATED NECTIN-1 localization#GO:0051179;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cell junction#GO:1902414;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha C-terminal fragment#P00177;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha N-terminal fragment#P00164;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha intracellular fragment#P00159;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha#P00160;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha transmembrane fragment#P00134 LEPOC|Ensembl=ENSLOCG00000011836.1|UniProtKB=W5N1P5 W5N1P5 PTHR46092:SF3 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-A11 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014888.1|UniProtKB=W5NCH5 W5NCH5 PTHR47979:SF17 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;regulation of biological process#GO:0050789;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;transport#GO:0006810;biological regulation#GO:0065007;regulation of localization#GO:0032879;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017241.1|UniProtKB=W5NL16 W5NL16 PTHR24418:SF94 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 2-BETA protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell migration#GO:0030334;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 synapse#GO:0045202;somatodendritic compartment#GO:0036477;anchoring junction#GO:0070161;neuron projection#GO:0043005;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;dendrite#GO:0030425;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;dendritic spine#GO:0043197;plasma membrane bounded cell projection#GO:0120025 non-receptor tyrosine protein kinase#PC00168 Gonadotropin-releasing hormone receptor pathway#P06664>Pyk2#P06730;CCKR signaling map#P06959>FAK2#P07218;Integrin signalling pathway#P00034>FAK#P00932;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PYK2#P00852 LEPOC|Ensembl=ENSLOCG00000001791.1|UniProtKB=W5M114 W5M114 RAB26 PTHR47978:SF65 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;regulation of vesicle-mediated transport#GO:0060627;regulation of exocytosis#GO:0017157 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011514.1|UniProtKB=W5N0I7 W5N0I7 PTHR13703:SF36 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 LEPOC|Ensembl=ENSLOCG00000005554.1|UniProtKB=W5ME99 W5ME99 GHITM PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001234.1|UniProtKB=W5LZ40 W5LZ40 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000000063.1|UniProtKB=W5LVB6 W5LVB6 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005129.1|UniProtKB=W5MCS2 W5MCS2 PTHR14049:SF1 LEPRECAN 1 PROLYL 3-HYDROXYLASE 2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000012291.1|UniProtKB=W5N3C0 W5N3C0 PTHR11243:SF25 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of signal transduction#GO:0009966;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb7#P00228 LEPOC|Ensembl=ENSLOCG00000013403.1|UniProtKB=W5N7B5 W5N7B5 PTHR11043:SF4 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-2 cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000016001.1|UniProtKB=W5NGE6 W5NGE6 BFSP1 PTHR14069:SF0 FILENSIN FILENSIN structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cell differentiation#GO:0030154;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;lens development in camera-type eye#GO:0002088;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009250.1|UniProtKB=W5MSC5 W5MSC5 PTHR19853:SF1 WD REPEAT CONTAINING PROTEIN 3 WDR3 TBC1 DOMAIN FAMILY MEMBER 31 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011188.1|UniProtKB=W5MZD6 W5MZD6 PTHR12765:SF5 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000002125.1|UniProtKB=W5M293 W5M293 PTHR18934:SF237 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA_RNA HELICASE DHX36 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000001767.1|UniProtKB=W5M0Y4 W5M0Y4 PTHR24232:SF91 G-PROTEIN COUPLED RECEPTOR TRANSMEMBRANE PROTEIN LOC653160 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015043.1|UniProtKB=W5ND12 W5ND12 PTHR16228:SF25 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006970.1|UniProtKB=W5MJ75 W5MJ75 PTHR43671:SF92 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK10 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009139.1|UniProtKB=W5MRY1 W5MRY1 PTHR24246:SF31 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G-PROTEIN COUPLED BILE ACID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004674.1|UniProtKB=W5MB36 W5MB36 PTHR12080:SF108 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004609.1|UniProtKB=W5MAW2 W5MAW2 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000002610.1|UniProtKB=W5M400 W5M400 PTHR24095:SF146 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015233.1|UniProtKB=W5NDN8 W5NDN8 PTHR18884:SF55 SEPTIN SEPTIN-6 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell division#GO:0051301;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;plasma membrane bounded cell projection assembly#GO:0120031;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003077.1|UniProtKB=W5M5G4 W5M5G4 PTHR19818:SF27 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004789.1|UniProtKB=W5MBJ6 W5MBJ6 PTHR11596:SF37 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011217.1|UniProtKB=W5MZH5 W5MZH5 RNF157 PTHR22996:SF1 MAHOGUNIN E3 UBIQUITIN LIGASE RNF157 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009852.1|UniProtKB=W5MUI8 W5MUI8 PTHR10218:SF213 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Endothelin signaling pathway#P00019>Gq#P00586;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Wnt signaling pathway#P00057>Galpha#P01451;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;PI3 kinase pathway#P00048>Galpha#P01199 LEPOC|Ensembl=ENSLOCG00000014076.1|UniProtKB=W5N9P5 W5N9P5 PTHR13902:SF10 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;molecular function inhibitor activity#GO:0140678;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of sodium ion transport#GO:0002028;macromolecule modification#GO:0043412;regulation of metal ion transport#GO:0010959;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of monoatomic ion transport#GO:0043269;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014258.1|UniProtKB=W5NA93 W5NA93 PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007852.1|UniProtKB=W5MMC3 W5MMC3 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT EPSILON antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000003646.1|UniProtKB=W5M7G8 W5M7G8 PTHR24027:SF433 CADHERIN-23 CADHERIN 27-RELATED cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000011523.1|UniProtKB=W5N0K3 W5N0K3 PTHR24241:SF132 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008054.1|UniProtKB=W5MN30 W5MN30 PTHR12349:SF3 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC5 palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000013375.1|UniProtKB=W5N7C9 W5N7C9 PTHR10676:SF183 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 2 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004601.1|UniProtKB=W5MAV9 W5MAV9 PTHR45864:SF5 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 1 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 LEPOC|Ensembl=ENSLOCG00000002530.1|UniProtKB=W5M3M7 W5M3M7 PTHR11544:SF143 COLD SHOCK DOMAIN CONTAINING PROTEINS NUCLEASE-SENSITIVE ELEMENT-BINDING PROTEIN 1-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000006891.1|UniProtKB=W5MIX3 W5MIX3 PTHR43917:SF9 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-1 glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006597.1|UniProtKB=W5MHX5 W5MHX5 PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000001458.1|UniProtKB=W5LZV6 W5LZV6 CFAP20 PTHR12458:SF8 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 LEPOC|Ensembl=ENSLOCG00000009523.1|UniProtKB=W5MTD1 W5MTD1 PTHR19139:SF161 AQUAPORIN TRANSPORTER AQUAPORIN-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372 transmembrane transport#GO:0055085;transport#GO:0006810;system process#GO:0003008;regulation of body fluid levels#GO:0050878;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;fluid transport#GO:0042044;localization#GO:0051179;response to stimulus#GO:0050896;water transport#GO:0006833;organic substance transport#GO:0071702;response to stress#GO:0006950;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;response to osmotic stress#GO:0006970;biological regulation#GO:0065007;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011204.1|UniProtKB=W5MZJ3 W5MZJ3 PTHR10857:SF51 COPINE COPINE-5 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000005345.1|UniProtKB=W5MDI7 W5MDI7 PANX PTHR15759:SF3 PANNEXIN PANNEXIN-3 wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002060.1|UniProtKB=W5M213 W5M213 PTHR45872:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 12 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000802.1|UniProtKB=W5LXR6 W5LXR6 PTHR43605:SF10 ACYL-COENZYME A SYNTHETASE ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3 ligase activity#GO:0016874;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014253.1|UniProtKB=W5NA88 W5NA88 PTHR45827:SF3 SORTING NEXIN SORTING NEXIN-33 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cell division#GO:0051301;cellular localization#GO:0051641;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;cell cycle process#GO:0022402;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytokinesis#GO:0000910;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013638.1|UniProtKB=W5N860 W5N860 PTHR22993:SF10 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 3 catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000016202.1|UniProtKB=W5NH61 W5NH61 IYD PTHR23026:SF90 NADPH NITROREDUCTASE IODOTYROSINE DEIODINASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012747.1|UniProtKB=W5N4X8 W5N4X8 PTHR10913:SF68 FOLLISTATIN-RELATED TOMOREGULIN-1-RELATED multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000001011.1|UniProtKB=W5LYF1 W5LYF1 PTHR11920:SF477 GUANYLYL CYCLASE GUANYLATE CYCLASE D adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000016588.1|UniProtKB=W5NIN3 W5NIN3 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;isoprenoid biosynthetic process#GO:0008299;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006747.1|UniProtKB=W5MIF2 W5MIF2 PTHR11453:SF37 ANION EXCHANGE PROTEIN ELECTRONEUTRAL SODIUM BICARBONATE EXCHANGER 1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013837.1|UniProtKB=W5N8W3 W5N8W3 PTHR24035:SF127 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN LAMININ SUBUNIT ALPHA-5-RELATED extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000002828.1|UniProtKB=W5M4R2 W5M4R2 PTHR47219:SF6 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000007140.1|UniProtKB=W5MJT5 W5MJT5 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015276.1|UniProtKB=W5NDT9 W5NDT9 PTHR11276:SF24 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA-DIRECTED DNA_RNA POLYMERASE MU DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000015112.1|UniProtKB=W5ND88 W5ND88 PTHR45791:SF1 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 1 LEPOC|Ensembl=ENSLOCG00000005737.1|UniProtKB=W5MEX1 W5MEX1 PTHR10845:SF277 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 20 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000003273.1|UniProtKB=W5M667 W5M667 PTHR12786:SF2 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002734.1|UniProtKB=W5M4C2 W5M4C2 PTHR10829:SF29 CORTACTIN AND DREBRIN COACTOSIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271 supramolecular complex#GO:0099080;cortical cytoskeleton#GO:0030863;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;site of polarized growth#GO:0030427 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000015616.1|UniProtKB=W5NF16 W5NF16 PTHR11743:SF28 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 3 voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000015696.1|UniProtKB=W5NFB3 W5NFB3 PTHR20916:SF26 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 LEPOC|Ensembl=ENSLOCG00000007994.1|UniProtKB=W5MMW8 W5MMW8 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000309.1|UniProtKB=W5LW29 W5LW29 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009045.1|UniProtKB=W5MRL6 W5MRL6 PTHR23052:SF1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010489.1|UniProtKB=W5MWU5 W5MWU5 PTHR12558:SF50 CELL DIVISION CYCLE 16,23,27 ASSEMBLY CHAPERONE OF RPL4-RELATED cell division#GO:0051301;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013437.1|UniProtKB=W5N7F9 W5N7F9 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000009257.1|UniProtKB=W5MSD1 W5MSD1 PTHR35347:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 LEPOC|Ensembl=ENSLOCG00000001974.1|UniProtKB=W5M1R2 W5M1R2 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;aminoacyltransferase activity#GO:0016755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013392.1|UniProtKB=W5N7A1 W5N7A1 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 19 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>TCR Beta#P01299 LEPOC|Ensembl=ENSLOCG00000009202.1|UniProtKB=W5MS68 W5MS68 PTHR10182:SF9 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39-LIKE protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000007750.1|UniProtKB=W5MM12 W5MM12 PTHR10730:SF6 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein hydroxylation#GO:0018126;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017573.1|UniProtKB=W5NM19 W5NM19 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017990.1|UniProtKB=W5NN82 W5NN82 PTHR24246:SF21 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016431.1|UniProtKB=W5NI36 W5NI36 DBX2 PTHR24331:SF4 DBX HOMEOBOX PROTEIN DBX2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000011933.1|UniProtKB=W5N219 W5N219 PTHR12818:SF0 TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000013393.1|UniProtKB=W5N7B0 W5N7B0 MGAT5B PTHR15075:SF6 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009627.1|UniProtKB=W5MTQ3 W5MTQ3 PTHR10742:SF364 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;nitrogen compound metabolic process#GO:0006807;biogenic amine metabolic process#GO:0006576;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;polyamine catabolic process#GO:0006598;polyamine metabolic process#GO:0006595;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008475.1|UniProtKB=W5MPL4 W5MPL4 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017591.1|UniProtKB=W5NM37 W5NM37 PTHR13832:SF343 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000495.1|UniProtKB=W5LWN7 W5LWN7 PTHR32094:SF5 FANCONI ANEMIA GROUP E PROTEIN FANCONI ANEMIA GROUP E PROTEIN protein-containing complex#GO:0032991;Fanconi anaemia nuclear complex#GO:0043240;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001810.1|UniProtKB=W5M133 W5M133 TSC22D2 PTHR46894:SF1 TSC22 DOMAIN FAMILY PROTEIN 2 TSC22 DOMAIN FAMILY PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000014274.1|UniProtKB=W5NAB6 W5NAB6 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000005561.1|UniProtKB=W5MEA9 W5MEA9 NUFIP1 PTHR13309:SF0 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 FMR1-INTERACTING PROTEIN NUFIP1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012122.1|UniProtKB=W5N2Q5 W5N2Q5 PTHR14903:SF4 SCLEROSTIN-RELATED SCLEROSTIN protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;ossification#GO:0001503;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008310.1|UniProtKB=W5MNY8 W5MNY8 M6PR PTHR15071:SF29 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012630.1|UniProtKB=W5N4J1 W5N4J1 PTHR28659:SF3 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 1 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;organelle disassembly#GO:1903008;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;catabolic process#GO:0009056;autophagy#GO:0006914;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008667.1|UniProtKB=W5MQ85 W5MQ85 PTHR34761:SF1 NUCLEOLUS AND NEURAL PROGENITOR PROTEIN NUCLEOLUS AND NEURAL PROGENITOR PROTEIN regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of Notch signaling pathway#GO:0008593;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007861.1|UniProtKB=W5MMD3 W5MMD3 PTHR46432:SF1 F-BOX ONLY PROTEIN 42 F-BOX ONLY PROTEIN 42 ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000004990.1|UniProtKB=W5MCA0 W5MCA0 PTHR12864:SF3 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010736.1|UniProtKB=W5MXP4 W5MXP4 PTHR48033:SF2 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011860.1|UniProtKB=W5N1S7 W5N1S7 CCDC134 PTHR14735:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 LEPOC|Ensembl=ENSLOCG00000001969.1|UniProtKB=W5M1M6 W5M1M6 PTHR14499:SF27 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD15 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009360.1|UniProtKB=W5MSQ7 W5MSQ7 PTHR10686:SF12 FOLATE TRANSPORTER REDUCED FOLATE TRANSPORTER antiporter activity#GO:0015297;small molecule binding#GO:0036094;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;amide binding#GO:0033218;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;active monoatomic ion transmembrane transporter activity#GO:0022853;amide transmembrane transporter activity#GO:0042887;heterocyclic compound binding#GO:1901363;monoatomic anion transmembrane transporter activity#GO:0008509;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001629.1|UniProtKB=W5M0J2 W5M0J2 PTHR21357:SF6 FAM172 FAMILY PROTEIN HOMOLOG CG10038 COTRANSCRIPTIONAL REGULATOR FAM172A HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011463.1|UniProtKB=W5N0C2 W5N0C2 PTHR14206:SF5 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2-LIKE PROTEIN 2 cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008580.1|UniProtKB=W5MPY3 W5MPY3 PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 galactosidase#PC00104 LEPOC|Ensembl=ENSLOCG00000013734.1|UniProtKB=W5N8I4 W5N8I4 PTHR23122:SF37 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK 55 KDA ERYTHROCYTE MEMBRANE PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;cellular process#GO:0009987;regulation of neurotransmitter secretion#GO:0046928;protein localization#GO:0008104;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of transport#GO:0051049;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004021.1|UniProtKB=W5M8U7 W5M8U7 PTHR24006:SF823 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010162.1|UniProtKB=W5MVN2 W5MVN2 PTHR22957:SF367 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 14 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of organelle organization#GO:0033043;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000013727.1|UniProtKB=W5N8I5 W5N8I5 DUOX2 PTHR11972:SF175 NADPH OXIDASE NAD(P)H OXIDASE (H2O2-FORMING) oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000279.1|UniProtKB=W5LW01 W5LW01 PTHR13139:SF6 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;mRNA binding#GO:0003729;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;double-stranded RNA binding#GO:0003725 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 LEPOC|Ensembl=ENSLOCG00000002705.1|UniProtKB=W5M468 W5M468 PTHR11214:SF23 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001504.1|UniProtKB=W5M043 W5M043 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED SUPERKILLER COMPLEX PROTEIN 3 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000021000|UniProtKB=P29667 P29667 mt-cyb PTHR19271:SF16 CYTOCHROME B CYTOCHROME B cellular anatomical entity#GO:0110165;membrane#GO:0016020 FAS signaling pathway#P00020>CytochromeC#P00620;Huntington disease#P00029>Cytochrome c#P00785 LEPOC|Ensembl=ENSLOCG00000001665.1|UniProtKB=W5M0N2 W5M0N2 PTHR46307:SF2 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;DNA methylation#GO:0006306;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;DNA modification#GO:0006304;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;DNA alkylation#GO:0006305;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008162.1|UniProtKB=W5MNG0 W5MNG0 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;protein processing involved in protein targeting to mitochondrion#GO:0006627;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein maturation#GO:0051604;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018327.1|UniProtKB=W5NP69 W5NP69 PTHR13516:SF8 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25-LIKE PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;endoribonuclease complex#GO:1902555;ribonuclease MRP complex#GO:0000172;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009457.1|UniProtKB=W5MT40 W5MT40 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001503.1|UniProtKB=W5M008 W5M008 PTHR45783:SF2 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 2 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000001811.1|UniProtKB=W5M131 W5M131 PTHR42951:SF4 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING ACYL-COENZYME A THIOESTERASE MBLAC2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009243.1|UniProtKB=W5MSB2 W5MSB2 PTHR11009:SF1 DER1-LIKE PROTEIN, DERLIN DERLIN-1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013073.1|UniProtKB=W5N646 W5N646 PTHR16064:SF3 BTB POZ DOMAIN CONTAINING 7 BTB_POZ DOMAIN-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000010564.1|UniProtKB=W5MX32 W5MX32 PTHR17097:SF0 NADH-UBIQUINONE OXIDOREDUCTASE KFYI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C1, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005786.1|UniProtKB=W5MF35 W5MF35 PTHR11134:SF10 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-1 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;axo-dendritic transport#GO:0008088;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006466.1|UniProtKB=W5MHF3 W5MHF3 st3gal8 PTHR46032:SF5 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 ST3 BETA-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE 8 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosphingolipid biosynthetic process#GO:0006688;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008146.1|UniProtKB=W5MND1 W5MND1 PTHR15905:SF1 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1B LEPOC|Ensembl=ENSLOCG00000007653.1|UniProtKB=W5MLP1 W5MLP1 PTHR19134:SF499 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007922.1|UniProtKB=W5MML3 W5MML3 PTHR16222:SF17 ADP-RIBOSYLGLYCOHYDROLASE SELENOPROTEIN J metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013528.1|UniProtKB=W5N7S3 W5N7S3 PTHR10745:SF8 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 DNA POLYMERASE SUBUNIT GAMMA-2, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011564.1|UniProtKB=W5N0Q1 W5N0Q1 PTHR43888:SF8 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 1 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006860.1|UniProtKB=W5MIV6 W5MIV6 PTHR14139:SF4 CALSYNTENIN CALSYNTENIN-1 regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of trans-synaptic signaling#GO:0099177;regulation of cell junction assembly#GO:1901888;positive regulation of synaptic transmission#GO:0050806;regulation of synapse structure or activity#GO:0050803;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010929.1|UniProtKB=W5MYE6 W5MYE6 PTHR24361:SF342 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ERK#P00907;B cell activation#P00010>MEKK#P00369;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 LEPOC|Ensembl=ENSLOCG00000002934.1|UniProtKB=W5M502 W5M502 PTHR12983:SF9 RING FINGER 10 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RNF10 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000006515.1|UniProtKB=W5MHP3 W5MHP3 PTHR46393:SF8 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT C2 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;complement activation#GO:0006956 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000011879.1|UniProtKB=W5N1U4 W5N1U4 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005733.1|UniProtKB=W5MEW5 W5MEW5 PTHR46809:SF3 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2 LEPOC|Ensembl=ENSLOCG00000008677.1|UniProtKB=W5MQ90 W5MQ90 PTHR11071:SF11 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003849.1|UniProtKB=W5M884 W5M884 PTHR21577:SF3 SHUGOSHIN SHUGOSHIN 1-RELATED centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000005058.1|UniProtKB=W5MCI1 W5MCI1 PTHR10288:SF135 KH DOMAIN CONTAINING RNA BINDING PROTEIN K HOMOLOGY DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311;negative regulation of cellular biosynthetic process#GO:0031327 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018031.1|UniProtKB=W5NNC3 W5NNC3 PTHR26451:SF881 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001908.1|UniProtKB=W5M1E6 W5M1E6 SIAH2 PTHR45877:SF4 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>SIAH-1#P01433 LEPOC|Ensembl=ENSLOCG00000001130.1|UniProtKB=W5LYR7 W5LYR7 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001710.1|UniProtKB=W5M0R1 W5M0R1 SLC9A3R2 PTHR14191:SF4 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007649.1|UniProtKB=W5MLN8 W5MLN8 PTHR10337:SF2 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>p52 SHC1#P07151;CCKR signaling map#P06959>p66 SHC1#P07168;CCKR signaling map#P06959>SHC1 @EGFR#P07083;FGF signaling pathway#P00021>Shc#P00639;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Shc#P00865;EGF receptor signaling pathway#P00018>Shc#P00554;Interleukin signaling pathway#P00036>Shc#P00997;PDGF signaling pathway#P00047>Shc#P01175;Angiogenesis#P00005>Shc#P00183;CCKR signaling map#P06959>SHC1#P07138;Ras Pathway#P04393>Shc#P04579;CCKR signaling map#P06959>p46 SHC1#P07098;Integrin signalling pathway#P00034>Shc#P00949 LEPOC|Ensembl=ENSLOCG00000014591.1|UniProtKB=W5NBG1 W5NBG1 PTHR10799:SF819 SNF2/RAD54 HELICASE FAMILY GLOBAL TRANSCRIPTION ACTIVATOR SNF2L1-RELATED ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000017223.1|UniProtKB=W5NKZ1 W5NKZ1 PTHR13439:SF7 CT120 PROTEIN PROTEIN CLN8 lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001528.1|UniProtKB=W5M038 W5M038 PTHR10024:SF252 SYNAPTOTAGMIN SYNAPTOTAGMIN-12 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000009357.1|UniProtKB=W5MSR4 W5MSR4 PTHR13748:SF31 COBW-RELATED ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007644.1|UniProtKB=W5MLL8 W5MLL8 PTHR24121:SF24 NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED ION CHANNEL NOMPC LEPOC|Ensembl=ENSLOCG00000004360.1|UniProtKB=W5MA00 W5MA00 PTHR21590:SF3 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549L LEPOC|Ensembl=ENSLOCG00000001495.1|UniProtKB=W5M004 W5M004 PTHR22028:SF4 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN SFI1 HOMOLOG phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000000998.1|UniProtKB=W5LYC2 W5LYC2 PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066 LEPOC|Ensembl=ENSLOCG00000001979.1|UniProtKB=W5M1N3 W5M1N3 PTHR31258:SF5 KERATINOCYTE-ASSOCIATED PROTEIN 3 TMEM54 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000001425.1|UniProtKB=W5LZS3 W5LZS3 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015830.1|UniProtKB=W5NFS8 W5NFS8 PTHR16024:SF9 XK-RELATED PROTEIN XK-RELATED PROTEIN 6 execution phase of apoptosis#GO:0097194;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;programmed cell death#GO:0012501;phospholipid transport#GO:0015914;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;biological regulation#GO:0065007;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001488.1|UniProtKB=W5M017 W5M017 PTHR11437:SF10 RIBONUCLEASE ANGIOGENIN-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012604.1|UniProtKB=W5N4F5 W5N4F5 PTHR10707:SF13 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009537.1|UniProtKB=W5MTF7 W5MTF7 PTHR15535:SF26 TRANSMEMBRANE PROTEIN 2-RELATED CELL SURFACE HYALURONIDASE LEPOC|Ensembl=ENSLOCG00000003949.1|UniProtKB=W5M8L4 W5M8L4 PTHR46900:SF4 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 FERM AND PDZ DOMAIN CONTAINING 2 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013317.1|UniProtKB=W5N702 W5N702 HESX1 PTHR46966:SF1 HOMEOBOX EXPRESSED IN ES CELLS 1 HOMEOBOX EXPRESSED IN ES CELLS 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;forebrain development#GO:0030900;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015905.1|UniProtKB=W5NG30 W5NG30 PTHR11202:SF1 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED HOMOLOG protein binding#GO:0005515;SH3 domain binding#GO:0017124;binding#GO:0005488 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516;Axon guidance mediated by Slit/Robo#P00008>Mena#P00345;Axon guidance mediated by netrin#P00009>Ena#P00361 LEPOC|Ensembl=ENSLOCG00000015017.1|UniProtKB=W5NCX7 W5NCX7 PTHR24340:SF32 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010795.1|UniProtKB=W5MXW7 W5MXW7 PTHR10083:SF373 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 2 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013927.1|UniProtKB=W5N961 W5N961 PTHR17604:SF1 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000002309.1|UniProtKB=W5M2U8 W5M2U8 PTHR24418:SF53 TYROSINE-PROTEIN KINASE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to biotic stimulus#GO:0009607;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;defense response#GO:0006952;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to endogenous stimulus#GO:0071495;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cell communication#GO:0007154;cell adhesion#GO:0007155;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of intrinsic apoptotic signaling pathway#GO:2001242;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;cellular response to steroid hormone stimulus#GO:0071383;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;developmental process#GO:0032502;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;negative regulation of programmed cell death#GO:0043069;intracellular steroid hormone receptor signaling pathway#GO:0030518;cellular response to organic cyclic compound#GO:0071407;intracellular receptor signaling pathway#GO:0030522;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;steroid hormone mediated signaling pathway#GO:0043401;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;negative regulation of apoptotic process#GO:0043066;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to hormone#GO:0009725;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;response to steroid hormone#GO:0048545;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 non-receptor tyrosine protein kinase#PC00168 Gonadotropin-releasing hormone receptor pathway#P06664>SRC#P06844;Angiogenesis#P00005>Src#P00184;CCKR signaling map#P06959>p62 SRC#P07047;Integrin signalling pathway#P00034>Src#P00940;CCKR signaling map#P06959>SRC @Galphaq#P07163;Cadherin signaling pathway#P00012>Src#P00468;CCKR signaling map#P06959>SRC#P07202;CCKR signaling map#P06959>p60 SRC#P07207;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>p54 SRC#P07109 LEPOC|Ensembl=ENSLOCG00000009761.1|UniProtKB=W5MU65 W5MU65 PTHR24278:SF34 COAGULATION FACTOR COAGULATION FACTOR VII,-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008139.1|UniProtKB=W5MNC3 W5MNC3 CPXM2 PTHR11532:SF45 PROTEASE M14 CARBOXYPEPTIDASE INACTIVE CARBOXYPEPTIDASE-LIKE PROTEIN X2 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016753.1|UniProtKB=W5NJ96 W5NJ96 PTHR21028:SF2 SI:CH211-156B7.4 CYTH DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013201.1|UniProtKB=W5N6J8 W5N6J8 PTHR24381:SF445 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF28.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015055.1|UniProtKB=W5ND18 W5ND18 PTHR13964:SF25 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000002537.1|UniProtKB=W5M3M3 W5M3M3 PTHR11668:SF472 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 LEPOC|Ensembl=ENSLOCG00000011812.1|UniProtKB=W5N1L7 W5N1L7 PTHR28348:SF1 UPF0193 PROTEIN EVG1 UPF0193 PROTEIN EVG1 LEPOC|Ensembl=ENSLOCG00000006099.1|UniProtKB=W5MG63 W5MG63 PTHR24023:SF861 COLLAGEN ALPHA ACETYLCHOLINESTERASE COLLAGENIC TAIL PEPTIDE structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000006626.1|UniProtKB=W5MHZ8 W5MHZ8 PTHR25465:SF14 B-BOX DOMAIN CONTAINING E3 UBIQUITIN-PROTEIN LIGASE TRIM65 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012596.1|UniProtKB=W5N4F1 W5N4F1 PTHR15283:SF3 GREMLIN 1 GREMLIN-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;animal organ development#GO:0048513;developmental process#GO:0032502;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005619.1|UniProtKB=W5MEJ1 W5MEJ1 PTHR31191:SF4 CENTROSOMAL PROTEIN CEP126 CENTROSOMAL PROTEIN OF 126 KDA cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006641.1|UniProtKB=W5MI12 W5MI12 PTHR22504:SF5 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000000683.1|UniProtKB=W5LXA2 W5LXA2 PTHR24034:SF96 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000014676.1|UniProtKB=W5NBR1 W5NBR1 PTHR11384:SF71 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;intracellular lipid transport#GO:0032365;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012757.1|UniProtKB=W5N505 W5N505 PTHR11629:SF90 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001624.1|UniProtKB=W5M0G0 W5M0G0 PTHR24023:SF855 COLLAGEN ALPHA COLLAGEN ALPHA-2(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000007029.1|UniProtKB=W5MJF5 W5MJF5 PTHR24073:SF910 DRAB5-RELATED RAS-RELATED PROTEIN RAB-22A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002737.1|UniProtKB=W5M4B9 W5M4B9 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;unfolded protein binding#GO:0051082;binding#GO:0005488;kinase binding#GO:0019900 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000001628.1|UniProtKB=W5M0H8 W5M0H8 PTHR28633:SF1 HERMANSKY-PUDLAK SYNDROME 3 PROTEIN BLOC-2 COMPLEX MEMBER HPS3 LEPOC|Ensembl=ENSLOCG00000012816.1|UniProtKB=W5N570 W5N570 PTHR46750:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 1 KUNITZ-TYPE PROTEASE INHIBITOR 1 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular component organization or biogenesis#GO:0071840;epidermis development#GO:0008544;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;epithelium development#GO:0060429;anatomical structure development#GO:0048856;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;extracellular matrix organization#GO:0030198 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000012165.1|UniProtKB=W5N2V1 W5N2V1 PTHR22811:SF37 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 9 vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;Golgi organization#GO:0007030;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000008242.1|UniProtKB=W5MNQ1 W5MNQ1 PTHR16265:SF1 PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000012674.1|UniProtKB=W5N4P1 W5N4P1 PTHR46046:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP10 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018034.1|UniProtKB=W5NNC6 W5NNC6 PTHR24248:SF136 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1B) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic cyclic compound#GO:0014070;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;dopamine receptor signaling pathway#GO:0007212;regulation of signal transduction#GO:0009966;cellular response to organic cyclic compound#GO:0071407;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 LEPOC|Ensembl=ENSLOCG00000006611.1|UniProtKB=W5MHY8 W5MHY8 PTHR11817:SF31 PYRUVATE KINASE PYRUVATE KINASE PKLR transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;cellular response to hormone stimulus#GO:0032870;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;carbohydrate derivative catabolic process#GO:1901136;cellular response to organic substance#GO:0071310;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;response to nitrogen compound#GO:1901698;cellular response to organonitrogen compound#GO:0071417;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;organonitrogen compound catabolic process#GO:1901565;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to stimulus#GO:0050896;response to hormone#GO:0009725;aromatic compound catabolic process#GO:0019439;response to chemical#GO:0042221;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132;Glycolysis#P00024>Pyruvate kinase#P00675 LEPOC|Ensembl=ENSLOCG00000008498.1|UniProtKB=W5MPN3 W5MPN3 PTHR24104:SF58 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 LEPOC|Ensembl=ENSLOCG00000001171.1|UniProtKB=W5LYV7 W5LYV7 SMIM22 PTHR36982:SF3 CLCA DOMAIN-CONTAINING PROTEIN SMALL INTEGRAL MEMBRANE PROTEIN 22 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000010980.1|UniProtKB=W5MYK9 W5MYK9 PTHR19325:SF570 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT COMPONENT 4 BINDING PROTEIN, MEMBRANE complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000012388.1|UniProtKB=W5N3Q3 W5N3Q3 PTHR15711:SF10 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008948.1|UniProtKB=W5MRA3 W5MRA3 PTHR45739:SF15 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 3 PRECURSOR anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012958.1|UniProtKB=W5N5Q1 W5N5Q1 PTHR10269:SF3 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001789.1|UniProtKB=W5M127 W5M127 PTHR46143:SF1 CALPAIN-7 CALPAIN-7 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000018163.1|UniProtKB=W5NNQ5 W5NNQ5 PTHR10489:SF922 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR FAMILY-LIKE-RELATED signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002971.1|UniProtKB=W5M540 W5M540 PTHR43658:SF5 SHORT-CHAIN DEHYDROGENASE/REDUCTASE SI:DKEY-238O13.4 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017364.1|UniProtKB=W5NLG0 W5NLG0 PTHR46048:SF10 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 1-4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001669.1|UniProtKB=W5M0M7 W5M0M7 PTHR22763:SF164 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004162.1|UniProtKB=W5M9B8 W5M9B8 PTHR24383:SF10 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013709.1|UniProtKB=W5N8E6 W5N8E6 PTHR21683:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA AND FLAGELLA ASSOCIATED PROTEIN 100 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014768.1|UniProtKB=W5NC25 W5NC25 PTHR21640:SF1 FAMILY NOT NAMED NESPRIN-4 LEPOC|Ensembl=ENSLOCG00000007306.1|UniProtKB=W5MKE3 W5MKE3 ADGRA1 PTHR45930:SF3 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012996.1|UniProtKB=W5N5U6 W5N5U6 PTHR12027:SF82 WNT RELATED PROTO-ONCOGENE WNT-3 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000006529.1|UniProtKB=W5MHN0 W5MHN0 PTHR22414:SF0 LEUCINE ZIPPER PROTEIN 2 LEUCINE ZIPPER PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004949.1|UniProtKB=W5MC57 W5MC57 PTHR45630:SF12 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A3 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;intracellular monoatomic ion homeostasis#GO:0006873 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013063.1|UniProtKB=W5N633 W5N633 COPS6 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000017930.1|UniProtKB=W5NN24 W5NN24 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015362.1|UniProtKB=W5NE50 W5NE50 PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007479.1|UniProtKB=W5ML23 W5ML23 PTHR23257:SF937 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010898.1|UniProtKB=W5MYB4 W5MYB4 PTHR22803:SF104 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED MACROPHAGE MANNOSE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 localization#GO:0051179;establishment of localization#GO:0051234;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010290.1|UniProtKB=W5MW44 W5MW44 PTHR15192:SF4 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 2 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of growth#GO:0040008;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558 LEPOC|Ensembl=ENSLOCG00000007292.1|UniProtKB=W5MKC2 W5MKC2 MARF1 PTHR14379:SF3 LIMKAIN B LKAP MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017892.1|UniProtKB=W5NMY6 W5NMY6 PTHR21734:SF10 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000012646.1|UniProtKB=W5N4K5 W5N4K5 PTHR46053:SF1 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF11 aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014183.1|UniProtKB=W5NA20 W5NA20 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000005796.1|UniProtKB=W5MF59 W5MF59 PTHR11255:SF37 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010826.1|UniProtKB=W5MY06 W5MY06 PTHR11177:SF248 CHITINASE CHITOTRIOSIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012694.1|UniProtKB=W5N4T1 W5N4T1 PTHR24416:SF137 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basal plasma membrane#GO:0009925;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 LEPOC|Ensembl=ENSLOCG00000009795.1|UniProtKB=W5MUB8 W5MUB8 PTHR48015:SF23 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010944.1|UniProtKB=W5MYH3 W5MYH3 PTHR45679:SF5 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005340.1|UniProtKB=W5MDH6 W5MDH6 PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006213.1|UniProtKB=W5MGJ6 W5MGJ6 PTHR12749:SF0 EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 DNA EXCISION REPAIR PROTEIN ERCC-1 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to UV#GO:0009411;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;mitotic recombination#GO:0006312;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular response to light stimulus#GO:0071482;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000012598.1|UniProtKB=W5N4F3 W5N4F3 PTHR23358:SF3 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;DNA modification#GO:0006304;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;hemopoiesis#GO:0030097;DNA demethylation#GO:0080111;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017066.1|UniProtKB=W5NKD2 W5NKD2 PTHR22872:SF2 BTK-BINDING PROTEIN-RELATED INHIBITOR OF BRUTON TYROSINE KINASE LEPOC|Ensembl=ENSLOCG00000008803.1|UniProtKB=W5MQQ4 W5MQQ4 PTHR46907:SF1 HEAT SHOCK PROTEIN BETA-7-RELATED HEAT SHOCK PROTEIN FAMILY B (SMALL) MEMBER 7 LEPOC|Ensembl=ENSLOCG00000010281.1|UniProtKB=W5MW37 W5MW37 PTHR24072:SF100 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOC GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Axon guidance mediated by semaphorins#P00007>Rho#P00341;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 LEPOC|Ensembl=ENSLOCG00000007628.1|UniProtKB=W5MLK5 W5MLK5 PTHR10807:SF42 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 2 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000018094.1|UniProtKB=W5NNI6 W5NNI6 PTHR17068:SF2 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE LEPOC|Ensembl=ENSLOCG00000014609.1|UniProtKB=W5NBH1 W5NBH1 PTHR22237:SF0 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;beta-catenin binding#GO:0008013 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009235.1|UniProtKB=W5MSA9 W5MSA9 PTHR45956:SF3 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012014.1|UniProtKB=W5N2C0 W5N2C0 PTHR12183:SF37 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 PROTEIN MDM4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 p53 pathway#P00059>Mdm2#P01483;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway feedback loops 2#P04398>Mdm2#P04663;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;P53 pathway feedback loops 1#P04392>Mdm2#P04536;p53 pathway feedback loops 2#P04398>MDM-2#G04709;p53 pathway#P00059>MDM-2#G01563;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674 LEPOC|Ensembl=ENSLOCG00000004129.1|UniProtKB=W5M988 W5M988 PTHR11861:SF1 MELANOCYTE PROTEIN PMEL 17-RELATED MELANOCYTE PROTEIN PMEL pigmentation#GO:0043473;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;melanosome organization#GO:0032438 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000004097.1|UniProtKB=W5M935 W5M935 PTHR11348:SF23 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CELLULAR COMMUNICATION NETWORK FACTOR 2B carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000017187.1|UniProtKB=W5NKT3 W5NKT3 PTHR31367:SF0 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;adenosine metabolic process#GO:0046085;purine-containing compound metabolic process#GO:0072521;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006161.1|UniProtKB=W5MGD1 W5MGD1 TVP23A PTHR13019:SF18 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG A cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010478.1|UniProtKB=W5MWT9 W5MWT9 PTHR12473:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000005303.1|UniProtKB=W5MDD3 W5MDD3 PTHR10334:SF581 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011079.1|UniProtKB=W5MZ02 W5MZ02 PTHR11705:SF19 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE O metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017568.1|UniProtKB=W5NM14 W5NM14 PTHR21461:SF52 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012748.1|UniProtKB=W5N4X3 W5N4X3 PTHR16057:SF1 WINS1, 2 PROTEIN PROTEIN LINES HOMOLOG 1 LEPOC|Ensembl=ENSLOCG00000018291.1|UniProtKB=W5NP33 W5NP33 PTHR11984:SF60 CONNEXIN GAP JUNCTION ALPHA-9 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000003436.1|UniProtKB=W5M6R7 W5M6R7 PTHR10751:SF100 GUANYLATE BINDING PROTEIN GUANYLATE BINDING PROTEIN 1 ISOFORM X1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002013.1|UniProtKB=W5M1S3 W5M1S3 PTHR13848:SF1 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 1 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009705.1|UniProtKB=W5MTZ0 W5MTZ0 PTHR11849:SF315 ETS TRANSCRIPTION FACTOR PU.1-LIKE transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010292.1|UniProtKB=W5MW54 W5MW54 PTHR10887:SF322 DNA2/NAM7 HELICASE FAMILY HELICASE MOV-10 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000001347.1|UniProtKB=W5LZH4 W5LZH4 PTHR13154:SF5 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B translation regulator activity#GO:0045182 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012390.1|UniProtKB=W5N3P6 W5N3P6 PTHR18945:SF93 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-1 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015816.1|UniProtKB=W5NFR2 W5NFR2 PTHR11950:SF7 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;ossification#GO:0001503;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Runt transcription factor#PC00254;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000005075.1|UniProtKB=W5MCK2 W5MCK2 PTHR22776:SF29 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006832.1|UniProtKB=W5MIQ5 W5MIQ5 MORC3 PTHR23336:SF17 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 3 protein binding#GO:0005515;methylated histone binding#GO:0035064;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PML body#GO:0016605 LEPOC|Ensembl=ENSLOCG00000001766.1|UniProtKB=W5M0Z0 W5M0Z0 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016235.1|UniProtKB=W5NHB5 W5NHB5 PTHR10983:SF8 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DELTA transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000014668.1|UniProtKB=W5NBP5 W5NBP5 PTHR10177:SF257 CYCLINS CYCLIN-P protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000013711.1|UniProtKB=W5N8E8 W5N8E8 PTHR11761:SF8 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005003.1|UniProtKB=W5MCD6 W5MCD6 PTHR45728:SF5 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 1 ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011547.1|UniProtKB=W5N0P4 W5N0P4 PTHR13808:SF29 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE P300 histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;N-acyltransferase activity#GO:0016410;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;chromatin DNA binding#GO:0031490;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694 histone modifying enzyme#PC00261 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;p53 pathway#P00059>CBP#P04623;Wnt signaling pathway#P00057>CBP#P01448;Gonadotropin-releasing hormone receptor pathway#P06664>p300#P06737;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>P300#P04611 LEPOC|Ensembl=ENSLOCG00000018366.1|UniProtKB=W5NPA8 W5NPA8 PTHR46675:SF3 E3 UBIQUITIN-PROTEIN LIGASE RNF182 E3 UBIQUITIN-PROTEIN LIGASE RNF182 LEPOC|Ensembl=ENSLOCG00000011244.1|UniProtKB=W5MZL9 W5MZL9 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008890.1|UniProtKB=W5MR17 W5MR17 PTHR13304:SF0 GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000016984.1|UniProtKB=W5NK35 W5NK35 PTHR11348:SF3 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CELLULAR COMMUNICATION NETWORK FACTOR 6 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000012765.1|UniProtKB=W5N4Z7 W5N4Z7 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 LEPOC|Ensembl=ENSLOCG00000015676.1|UniProtKB=W5NF97 W5NF97 PTHR45653:SF3 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;syncytium formation by plasma membrane fusion#GO:0000768;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;syncytium formation#GO:0006949;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008188.1|UniProtKB=W5MNK9 W5MNK9 PTHR45670:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001437.1|UniProtKB=W5LZS9 W5LZS9 PTHR14898:SF4 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017581.1|UniProtKB=W5NM27 W5NM27 PTHR24225:SF52 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011828.1|UniProtKB=W5N1N9 W5N1N9 PTHR23086:SF21 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000110.1|UniProtKB=W5LVG5 W5LVG5 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001213.1|UniProtKB=W5LZ13 W5LZ13 PTHR24103:SF695 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-18P12.4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016469.1|UniProtKB=W5NI84 W5NI84 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015266.1|UniProtKB=W5NDT7 W5NDT7 PTHR11200:SF176 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000015026.1|UniProtKB=W5NCY8 W5NCY8 PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000017299.1|UniProtKB=W5NL95 W5NL95 PTHR23049:SF10 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 11 cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 muscle structure development#GO:0061061;skeletal muscle organ development#GO:0060538;muscle organ development#GO:0007517;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;skeletal muscle tissue development#GO:0007519;tissue development#GO:0009888;muscle tissue development#GO:0060537 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012492.1|UniProtKB=W5N427 W5N427 PTHR11629:SF68 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005222.1|UniProtKB=W5MD34 W5MD34 PTHR10102:SF0 DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000005695.1|UniProtKB=W5MES1 W5MES1 PTHR23389:SF33 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;single-stranded DNA helicase activity#GO:0017116;catalytic activity, acting on DNA#GO:0140097 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011358.1|UniProtKB=W5N009 W5N009 PTHR10901:SF8 TROPOMODULIN TROPOMODULIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014348.1|UniProtKB=W5NAL5 W5NAL5 PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE protein binding#GO:0005515;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;protein secretion#GO:0009306;lipid modification#GO:0030258;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;signal release#GO:0023061;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cell-cell signaling#GO:0007267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;secretion by cell#GO:0032940;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;biological regulation#GO:0065007;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008888.1|UniProtKB=W5MR08 W5MR08 COMMD10 PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000009133.1|UniProtKB=W5MRX4 W5MRX4 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000013845.1|UniProtKB=W5N8Y9 W5N8Y9 PTHR24025:SF25 DESMOGLEIN FAMILY MEMBER FAT ATYPICAL CADHERIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000003702.1|UniProtKB=W5M7P7 W5M7P7 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001809.1|UniProtKB=W5M138 W5M138 PTHR46076:SF4 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;catalytic activity#GO:0003824;chromatin binding#GO:0003682;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000232.1|UniProtKB=W5LVU9 W5LVU9 PTHR24399:SF32 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 37 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010294.1|UniProtKB=W5MW49 W5MW49 PTHR23113:SF249 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013843.1|UniProtKB=W5N8W7 W5N8W7 ECM2 PTHR46544:SF1 EXTRACELLULAR MATRIX PROTEIN 2-RELATED EXTRACELLULAR MATRIX PROTEIN 2 collagen binding#GO:0005518;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;positive regulation of cell-substrate adhesion#GO:0010811;external encapsulating structure organization#GO:0045229;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular component organization#GO:0016043;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;extracellular matrix organization#GO:0030198;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cellular process#GO:0048522 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000004630.1|UniProtKB=W5MAY6 W5MAY6 ARMH2 PTHR37679:SF1 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000008705.1|UniProtKB=W5MQD6 W5MQD6 PTHR13455:SF4 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-BETA negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003703.1|UniProtKB=W5M7P4 W5M7P4 PTHR10845:SF277 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 20 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000006980.1|UniProtKB=W5MJ87 W5MJ87 PTHR14024:SF48 PERILIPIN PERILIPIN 6 localization#GO:0051179;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015612.1|UniProtKB=W5NF14 W5NF14 PTHR10261:SF0 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009468.1|UniProtKB=W5MT62 W5MT62 PTHR11073:SF16 CALRETICULIN AND CALNEXIN CALRETICULIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;ERAD pathway#GO:0036503;cellular biosynthetic process#GO:0044249;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016767.1|UniProtKB=W5NJB7 W5NJB7 PTHR24073:SF263 DRAB5-RELATED RAB-LIKE PROTEIN 2A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000009153.1|UniProtKB=W5MS04 W5MS04 PTHR46680:SF1 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR ALPHA NF-kappaB binding#GO:0051059;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 immune response-regulating signaling pathway#GO:0002764;cellular localization#GO:0051641;activation of immune response#GO:0002253;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;cell communication#GO:0007154;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;macromolecule localization#GO:0033036;pattern recognition receptor signaling pathway#GO:0002221;toll-like receptor 4 signaling pathway#GO:0034142;positive regulation of response to stimulus#GO:0048584;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833;negative regulation of DNA-binding transcription factor activity#GO:0043433;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;T cell activation#P00053>I kappa B#P01323;CCKR signaling map#P06959>IKBalpha#P07053;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IkappaB#P00857;Toll receptor signaling pathway#P00054>IkappaB#P01338;Apoptosis signaling pathway#P00006>IkappaB#P00292;B cell activation#P00010>I kappa B#P00392 LEPOC|Ensembl=ENSLOCG00000003609.1|UniProtKB=W5M7B7 W5M7B7 PTHR15073:SF3 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 2 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000005357.1|UniProtKB=W5MDJ4 W5MDJ4 PTHR11728:SF32 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)], CYTOPLASMIC oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;glycerol-3-phosphate metabolic process#GO:0006072;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001431.1|UniProtKB=W5LZS2 W5LZS2 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016589.1|UniProtKB=W5NIN2 W5NIN2 PTHR45746:SF7 LP21163P REGULATOR OF G-PROTEIN SIGNALING 7 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000009247.1|UniProtKB=W5MSD3 W5MSD3 HNRNPH3 PTHR13976:SF36 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006019.1|UniProtKB=W5MFV8 W5MFV8 PTHR10516:SF452 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYLPROLYL ISOMERASE peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 LEPOC|Ensembl=ENSLOCG00000012968.1|UniProtKB=W5N5R3 W5N5R3 PTHR15744:SF2 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006292.1|UniProtKB=W5MGU1 W5MGU1 PTHR11588:SF112 TUBULIN TUBULIN BETA-1 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 LEPOC|Ensembl=ENSLOCG00000008597.1|UniProtKB=W5MPZ1 W5MPZ1 PTHR42757:SF6 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEURONAL GROWTH REGULATOR 1 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011784.1|UniProtKB=W5N1I7 W5N1I7 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002086.1|UniProtKB=W5M235 W5M235 ARHGEF26 PTHR12845:SF4 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 26 positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010361.1|UniProtKB=W5MWD6 W5MWD6 SNTN PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000006822.1|UniProtKB=W5MIN9 W5MIN9 PTHR16505:SF8 PROTEIN LZIC PROTEIN LZIC LEPOC|Ensembl=ENSLOCG00000007189.1|UniProtKB=W5MJZ9 W5MJZ9 PTHR13859:SF12 ATROPHIN-RELATED ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006689.1|UniProtKB=W5MI67 W5MI67 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018249.1|UniProtKB=W5NNZ1 W5NNZ1 PTHR11937:SF54 ACTIN ACTIN-LIKE 11 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005126.1|UniProtKB=W5MCR0 W5MCR0 PTHR31501:SF3 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015324.1|UniProtKB=W5NDZ8 W5NDZ8 PTHR24012:SF692 RNA BINDING PROTEIN TIA1 CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017395.1|UniProtKB=W5NLJ1 W5NLJ1 CPN2 PTHR24366:SF159 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS CD180 MOLECULE cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000011818.1|UniProtKB=W5N1N1 W5N1N1 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003414.1|UniProtKB=W5M6N2 W5M6N2 PTHR23192:SF68 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001214.1|UniProtKB=W5LZ12 W5LZ12 PTHR18843:SF7 TORSIN-1A-INTERACTING PROTEIN LAMINA-ASSOCIATED POLYPEPTIDE 1B ISOFORM 1-RELATED cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014536.1|UniProtKB=W5NB83 W5NB83 PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG molecular adaptor activity#GO:0060090;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;ubiquitin ligase-substrate adaptor activity#GO:1990756;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;post-translational protein modification#GO:0043687;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of proteolysis#GO:0030162;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001109.1|UniProtKB=W5LYN9 W5LYN9 PTHR46841:SF7 OX-2 MEMBRANE GLYCOPROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of response to stress#GO:0080134;negative regulation of inflammatory response#GO:0050728;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;negative regulation of defense response#GO:0031348;cellular process#GO:0009987 cell surface#GO:0009986;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000001147.1|UniProtKB=W5LYT4 W5LYT4 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000014614.1|UniProtKB=W5NBH4 W5NBH4 PTHR24366:SF53 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 1 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000011498.1|UniProtKB=W5N0H5 W5N0H5 PTHR24416:SF485 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013878.1|UniProtKB=W5N913 W5N913 PTHR10353:SF336 GLYCOSYL HYDROLASE LACTASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011724.1|UniProtKB=W5N1A2 W5N1A2 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR transporter activity#GO:0005215;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule localization#GO:0033036;carbohydrate derivative catabolic process#GO:1901136;transport#GO:0006810;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;lipid transport#GO:0006869;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;localization#GO:0051179;organic substance transport#GO:0071702;membrane lipid metabolic process#GO:0006643;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013536.1|UniProtKB=W5N7T0 W5N7T0 PTHR11523:SF26 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-2 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017372.1|UniProtKB=W5NLG8 W5NLG8 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 LEPOC|Ensembl=ENSLOCG00000017954.1|UniProtKB=W5NN48 W5NN48 PTHR22923:SF102 CEREBELLIN-RELATED CEREBELLIN 13-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003176.1|UniProtKB=W5M5U4 W5M5U4 PTHR31994:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 LEPOC|Ensembl=ENSLOCG00000006564.1|UniProtKB=W5MHR7 W5MHR7 PTHR12447:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007533.1|UniProtKB=W5ML81 W5ML81 PTHR15414:SF5 OS-9-RELATED PROTEIN OS-9 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017645.1|UniProtKB=W5NM91 W5NM91 PTHR26450:SF87 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014621.1|UniProtKB=W5NBI7 W5NBI7 PTHR24418:SF458 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE CSK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>Csk#P00913;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>CSK#P07072;T cell activation#P00053>Csk#P01304 LEPOC|Ensembl=ENSLOCG00000014686.1|UniProtKB=W5NBR7 W5NBR7 PTHR21236:SF1 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF6 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017835.1|UniProtKB=W5NMS9 W5NMS9 TWIST2 PTHR23349:SF70 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002604.1|UniProtKB=W5M3W6 W5M3W6 PTHR11731:SF193 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003006.1|UniProtKB=W5M5B9 W5M5B9 PTHR12752:SF4 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7 LEPOC|Ensembl=ENSLOCG00000014361.1|UniProtKB=W5NAN8 W5NAN8 PTHR11814:SF113 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015471.1|UniProtKB=W5NEI3 W5NEI3 PTHR23055:SF164 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010995.1|UniProtKB=W5MYM8 W5MYM8 PTHR20952:SF4 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN RETICULOPHAGY REGULATOR 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006494.1|UniProtKB=W5MHI6 W5MHI6 PTHR10558:SF1 SOMATOSTATIN CORTISTATIN neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000010538.1|UniProtKB=W5MX05 W5MX05 PTHR23036:SF193 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT BETA-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003146.1|UniProtKB=W5M5Q4 W5M5Q4 QTRT2 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006015.1|UniProtKB=W5MFV4 W5MFV4 PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI TRANSAMIDASE COMPONENT PIG-S lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000006687.1|UniProtKB=W5MI66 W5MI66 PTHR47980:SF42 LD44762P RAS-RELATED PROTEIN RAB-13 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;protein kinase A signaling#GO:0010737;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;secretion#GO:0046903;intracellular signal transduction#GO:0035556;signaling#GO:0023052;secretion by cell#GO:0032940;localization within membrane#GO:0051668;cellular response to stimulus#GO:0051716;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;response to stimulus#GO:0050896;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003484.1|UniProtKB=W5M6X5 W5M6X5 PTHR46625:SF1 72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE PHOSPHATIDYLINOSITOL POLYPHOSPHATE 5-PHOSPHATASE TYPE IV hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 axoneme#GO:0005930;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006200.1|UniProtKB=W5MGH9 W5MGH9 PTHR12002:SF9 CLAUDIN CLAUDIN-18 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000008457.1|UniProtKB=W5MPI5 W5MPI5 PTHR23081:SF36 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 General transcription regulation#P00023>TFIIF#P00665;Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394 LEPOC|Ensembl=ENSLOCG00000017458.1|UniProtKB=W5NLQ4 W5NLQ4 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007289.1|UniProtKB=W5MKC3 W5MKC3 KNDC1 PTHR21560:SF0 VERY KIND PROTEIN KINASE NON-CATALYTIC C-LOBE DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cellular component organization#GO:0051128;regulation of neuron projection development#GO:0010975 somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;dendrite#GO:0030425;guanyl-nucleotide exchange factor complex#GO:0032045;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;plasma membrane bounded cell projection#GO:0120025 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005799.1|UniProtKB=W5MF48 W5MF48 PTHR11219:SF9 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-4 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000006166.1|UniProtKB=W5MGD8 W5MGD8 KATNB1 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017459.1|UniProtKB=W5NLQ5 W5NLQ5 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002723.1|UniProtKB=W5M4A6 W5M4A6 ANKRD50 PTHR24123:SF65 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001471.1|UniProtKB=W5M048 W5M048 PTHR13817:SF68 TITIN CELL ADHESION MOLECULE DSCAM cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010527.1|UniProtKB=W5MWZ9 W5MWZ9 MAST4 PTHR24356:SF224 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007048.1|UniProtKB=W5MJH9 W5MJH9 FADS1 PTHR19353:SF57 FATTY ACID DESATURASE 2 ACYL-COA (8-3)-DESATURASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018245.1|UniProtKB=W5NNY7 W5NNY7 PTHR19268:SF8 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 27-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005107.1|UniProtKB=W5MCP3 W5MCP3 VSIG2 PTHR45046:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006982.1|UniProtKB=W5MJ89 W5MJ89 PTHR14254:SF6 GENE 33 POLYPEPTIDE NON-SPECIFIC PROTEIN-TYROSINE KINASE regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of epithelial cell differentiation#GO:0030856;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of ERBB signaling pathway#GO:1901184;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000011464.1|UniProtKB=W5N0C4 W5N0C4 PTHR44942:SF6 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN NOVEL PROTEIN LEPOC|Ensembl=ENSLOCG00000015296.1|UniProtKB=W5NDV8 W5NDV8 PTHR24117:SF6 AGAP007537-PB BCL-6 COREPRESSOR-LIKE PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003416.1|UniProtKB=W5M6P3 W5M6P3 PTHR13720:SF24 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 90 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017823.1|UniProtKB=W5NMR7 W5NMR7 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005018.1|UniProtKB=W5MCD0 W5MCD0 PTHR48051:SF58 FAMILY NOT NAMED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012134.1|UniProtKB=W5N2R7 W5N2R7 PTHR45712:SF17 AGAP008170-PA LUMICAN-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000007489.1|UniProtKB=W5ML34 W5ML34 PTHR22765:SF345 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 215 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001737.1|UniProtKB=W5M0U9 W5M0U9 PTHR23507:SF36 ZGC:174356 THYMIC STROMAL COTRANSPORTER HOMOLOG ISOFORM X2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010003.1|UniProtKB=W5MV20 W5MV20 PTHR15040:SF3 DERMATOPONTIN-RELATED SI:DKEY-14D8.6-RELATED cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;collagen fibril organization#GO:0030199;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001741.1|UniProtKB=W5M0V8 W5M0V8 GMEB2 PTHR10417:SF2 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013500.1|UniProtKB=W5N7N7 W5N7N7 PTHR13866:SF26 SPARC OSTEONECTIN SPARC cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000003550.1|UniProtKB=W5M754 W5M754 ATP4A PTHR43294:SF10 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013936.1|UniProtKB=W5N973 W5N973 PTHR20974:SF1 UPF0585 PROTEIN CG18661 METHYLTRANSFERASE-LIKE 26 B LEPOC|Ensembl=ENSLOCG00000015009.1|UniProtKB=W5NCW8 W5NCW8 PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;synapse#GO:0045202;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008221.1|UniProtKB=W5MNM4 W5MNM4 PTHR11188:SF14 ARRESTIN DOMAIN CONTAINING PROTEIN THIOREDOXIN-INTERACTING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008024.1|UniProtKB=W5MMY4 W5MMY4 PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 LARGE RIBOSOMAL SUBUNIT PROTEIN ML64 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009054.1|UniProtKB=W5MRN1 W5MRN1 PTHR11879:SF38 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;aspartate metabolic process#GO:0006531;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005072.1|UniProtKB=W5MCK1 W5MCK1 PTHR24343:SF457 SERINE/THREONINE KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010248.1|UniProtKB=W5MW01 W5MW01 PTHR10316:SF12 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002468.1|UniProtKB=W5M3F6 W5M3F6 PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;chromatin organization#GO:0006325;protein-RNA complex organization#GO:0071826;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Ino80 complex#GO:0031011;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000008467.1|UniProtKB=W5MPJ1 W5MPJ1 PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000015578.1|UniProtKB=W5NEX1 W5NEX1 PTHR46555:SF1 UBIQUITIN-LIKE PROTEIN 4A UBIQUITIN-LIKE PROTEIN 4A LEPOC|Ensembl=ENSLOCG00000002310.1|UniProtKB=W5M2U6 W5M2U6 PTHR33887:SF5 PB1 DOMAIN-CONTAINING PROTEIN PB1 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014968.1|UniProtKB=W5NCS1 W5NCS1 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000005636.1|UniProtKB=W5MEK5 W5MEK5 MYOM3 PTHR13817:SF89 TITIN MYOMESIN-3 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007999.1|UniProtKB=W5MMV2 W5MMV2 PTHR11071:SF292 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002721.1|UniProtKB=W5M489 W5M489 PTHR23354:SF131 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MTOR-ASSOCIATED PROTEIN MEAK7 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009598.1|UniProtKB=W5MTL5 W5MTL5 PTHR47266:SF28 ENDONUCLEASE-RELATED TRANSPOSON TF2-1 POLYPROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000009814.1|UniProtKB=W5MUF3 W5MUF3 PTHR11932:SF68 CULLIN CULLIN-4A enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006759.1|UniProtKB=W5MIF8 W5MIF8 PTHR13318:SF193 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 16 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000011905.1|UniProtKB=W5N1Z2 W5N1Z2 PTHR19304:SF8 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 LEPOC|Ensembl=ENSLOCG00000008078.1|UniProtKB=W5MN52 W5MN52 PTHR24409:SF334 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 653 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003795.1|UniProtKB=W5M819 W5M819 PTHR15860:SF1 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of nitrogen compound metabolic process#GO:0051171;regulation of response to endoplasmic reticulum stress#GO:1905897;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of response to stress#GO:0080134;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteolysis#GO:0045862;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of proteasomal protein catabolic process#GO:0061136;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005552.1|UniProtKB=W5ME95 W5ME95 PTHR10291:SF43 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010630.1|UniProtKB=W5MXB6 W5MXB6 PTHR48092:SF7 KNIRPS-RELATED PROTEIN-RELATED STEROID HORMONE RECEPTOR ERR2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004581.1|UniProtKB=W5MAS3 W5MAS3 PTHR14464:SF4 EXONUCLEASE V EXONUCLEASE V hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;5'-3' exonuclease activity#GO:0008409;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;exonuclease activity#GO:0004527 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002797.1|UniProtKB=W5M4I4 W5M4I4 PTHR10300:SF6 CALCIPRESSIN CALCIPRESSIN-3 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001645.1|UniProtKB=W5M0J1 W5M0J1 PTHR10840:SF0 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008470.1|UniProtKB=W5MPK6 W5MPK6 PTHR43173:SF28 ABC1 FAMILY PROTEIN AARF DOMAIN CONTAINING KINASE 5 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011443.1|UniProtKB=W5N099 W5N099 PTHR11556:SF13 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;hexose biosynthetic process#GO:0019319;oligosaccharide biosynthetic process#GO:0009312;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007746.1|UniProtKB=W5MM07 W5MM07 PTHR10857:SF3 COPINE COPINE-2 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000009928.1|UniProtKB=W5MUS9 W5MUS9 PTHR12329:SF2 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 5 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-folding chaperone binding#GO:0051087 negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of protein stability#GO:0031647;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;protein stabilization#GO:0050821;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of protein ubiquitination#GO:0031397;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015300.1|UniProtKB=W5NDW7 W5NDW7 PTHR45735:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011898.1|UniProtKB=W5N1X3 W5N1X3 PTHR11595:SF55 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER EF-HAND AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1-LIKE ISOFORM X1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000470.1|UniProtKB=W5LWK7 W5LWK7 ZDHHC18 PTHR22883:SF348 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC18-B palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005673.1|UniProtKB=W5MEP4 W5MEP4 PTHR10822:SF8 GLYPICAN GLYPICAN-1 fibroblast growth factor binding#GO:0017134;growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of protein localization to membrane#GO:1905475;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;cell migration#GO:0016477;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of protein localization#GO:0032880 cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006935.1|UniProtKB=W5MJ28 W5MJ28 PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004356.1|UniProtKB=W5M9Z4 W5M9Z4 PTHR10553:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007147.1|UniProtKB=W5MJU3 W5MJU3 RDH8 PTHR43391:SF8 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;NAD-retinol dehydrogenase activity#GO:0004745;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 retinoid metabolic process#GO:0001523;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;retinol metabolic process#GO:0042572;isoprenoid metabolic process#GO:0006720;hormone metabolic process#GO:0042445;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;terpenoid metabolic process#GO:0006721 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017917.1|UniProtKB=W5NN11 W5NN11 PTHR11537:SF281 VOLTAGE-GATED POTASSIUM CHANNEL BTB DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013463.1|UniProtKB=W5N7J3 W5N7J3 PTHR28625:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 regulation of microtubule-based process#GO:0032886;positive regulation of organelle organization#GO:0010638;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cell cycle#GO:0045787;regulation of cilium assembly#GO:1902017;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of centrosome cycle#GO:0046605;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;positive regulation of cell cycle process#GO:0090068;regulation of cell projection assembly#GO:0060491;regulation of organelle assembly#GO:1902115;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of centriole replication#GO:0046599;regulation of cell cycle#GO:0051726;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of centrosome duplication#GO:0010824 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000002736.1|UniProtKB=W5M4B0 W5M4B0 PTHR19375:SF395 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN ISOFORM X1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 LEPOC|Ensembl=ENSLOCG00000014197.1|UniProtKB=W5NA30 W5NA30 PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000000102.1|UniProtKB=W5LVF5 W5LVF5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004035.1|UniProtKB=W5M8W9 W5M8W9 PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000002356.1|UniProtKB=W5M301 W5M301 PTHR11537:SF88 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004474.1|UniProtKB=W5MAE7 W5MAE7 PTHR46180:SF1 VINCULIN VINCULIN protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 LEPOC|Ensembl=ENSLOCG00000004645.1|UniProtKB=W5MB06 W5MB06 PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010121.1|UniProtKB=W5MVI4 W5MVI4 PTHR24027:SF419 CADHERIN-23 CADHERIN-17 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000007830.1|UniProtKB=W5MMA1 W5MMA1 PTHR47135:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000011452.1|UniProtKB=W5N0B2 W5N0B2 PTHR24393:SF18 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 652 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007020.1|UniProtKB=W5MJD9 W5MJD9 PTHR10519:SF20 GABA-B RECEPTOR G-PROTEIN COUPLED RECEPTOR 156-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004014.1|UniProtKB=W5M8V3 W5M8V3 LACTB2 PTHR23131:SF0 ENDORIBONUCLEASE LACTB2 ENDORIBONUCLEASE LACTB2 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005143.1|UniProtKB=W5MCT5 W5MCT5 PTHR46575:SF1 AMYLOID PROTEIN-BINDING PROTEIN 2 AMYLOID PROTEIN-BINDING PROTEIN 2 ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000009520.1|UniProtKB=W5MTC5 W5MTC5 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000009450.1|UniProtKB=W5MT28 W5MT28 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000001871.1|UniProtKB=W5M1A6 W5M1A6 SART1 PTHR14152:SF5 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;spliceosomal tri-snRNP complex#GO:0097526;U4/U6 x U5 tri-snRNP complex#GO:0046540;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006942.1|UniProtKB=W5MJ40 W5MJ40 PTHR10913:SF6 FOLLISTATIN-RELATED FOLLISTATIN protein-containing complex binding#GO:0044877;activin binding#GO:0048185;binding#GO:0005488 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06885;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#P06835;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06671 LEPOC|Ensembl=ENSLOCG00000011516.1|UniProtKB=W5N0M1 W5N0M1 PTHR10082:SF42 INTEGRIN BETA SUBUNIT INTEGRIN BETA-4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000010814.1|UniProtKB=W5MXZ7 W5MXZ7 SLC26A9 PTHR11814:SF17 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005771.1|UniProtKB=W5MF19 W5MF19 PTHR13578:SF19 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006030.1|UniProtKB=W5MG08 W5MG08 PTHR24198:SF192 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT A non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014221.1|UniProtKB=W5NA55 W5NA55 PTHR22804:SF40 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000009506.1|UniProtKB=W5MTB3 W5MTB3 PTHR10127:SF838 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006006.1|UniProtKB=W5MFU8 W5MFU8 PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000014339.1|UniProtKB=W5NAK4 W5NAK4 PTHR48012:SF15 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCK#P00268 LEPOC|Ensembl=ENSLOCG00000000983.1|UniProtKB=W5LY98 W5LY98 PTHR15546:SF2 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN, 2A DDT DOMAIN-CONTAINING PROTEIN DDB_G0282237 LEPOC|Ensembl=ENSLOCG00000003005.1|UniProtKB=W5M5E6 W5M5E6 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 LEPOC|Ensembl=ENSLOCG00000001994.1|UniProtKB=W5M1P6 W5M1P6 PTHR24006:SF937 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013884.1|UniProtKB=W5N912 W5N912 PTHR10980:SF9 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014834.1|UniProtKB=W5NCA7 W5NCA7 PTHR45791:SF5 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 stereocilium#GO:0032420;cytoplasm#GO:0005737;stereocilium bundle#GO:0032421;cluster of actin-based cell projections#GO:0098862;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Rac#P04559 LEPOC|Ensembl=ENSLOCG00000002578.1|UniProtKB=W5M3U5 W5M3U5 PTHR11792:SF22 ARRESTIN BETA-ARRESTIN-1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;receptor internalization#GO:0031623;negative regulation of signaling#GO:0023057;transport#GO:0006810;endocytosis#GO:0006897;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;receptor-mediated endocytosis#GO:0006898;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR1#P05925;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 LEPOC|Ensembl=ENSLOCG00000003238.1|UniProtKB=W5M615 W5M615 PTHR24388:SF99 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF52.1-LIKE ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013096.1|UniProtKB=W5N672 W5N672 PTHR24343:SF477 SERINE/THREONINE KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001679.1|UniProtKB=W5M0Q0 W5M0Q0 PTHR11875:SF75 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003259.1|UniProtKB=W5M642 W5M642 PTHR12850:SF5 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000927.1|UniProtKB=W5LY31 W5LY31 PTHR12301:SF4 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM DOMAIN-CONTAINING PROTEIN SAMSN-1 LEPOC|Ensembl=ENSLOCG00000008703.1|UniProtKB=W5MQD4 W5MQD4 PTHR12929:SF1 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 2 transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009218.1|UniProtKB=W5MS85 W5MS85 PTHR46925:SF3 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-K RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;positive regulation of locomotion#GO:0040017;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;sperm flagellum#GO:0036126;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012637.1|UniProtKB=W5N4K7 W5N4K7 PTHR23118:SF42 ATP-CITRATE SYNTHASE ATP-CITRATE SYNTHASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Citrate Lyase#P03137 LEPOC|Ensembl=ENSLOCG00000013206.1|UniProtKB=W5N6K5 W5N6K5 DCTN6 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000179.1|UniProtKB=W5LVP3 W5LVP3 PTHR46890:SF29 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000014719.1|UniProtKB=W5NBW7 W5NBW7 PTHR46842:SF1 TRANSMEMBRANE PROTEIN 266 TRANSMEMBRANE PROTEIN 266 LEPOC|Ensembl=ENSLOCG00000007867.1|UniProtKB=W5MME0 W5MME0 PTHR11818:SF55 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B1-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010690.1|UniProtKB=W5MXI8 W5MXI8 PTHR18945:SF498 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013391.1|UniProtKB=W5N7A0 W5N7A0 PTHR43205:SF7 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 1 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004594.1|UniProtKB=W5MAU3 W5MAU3 PTHR10794:SF78 ABHYDROLASE DOMAIN-CONTAINING PROTEIN ABHYDROLASE DOMAIN-CONTAINING 15A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007769.1|UniProtKB=W5MM26 W5MM26 PTHR32470:SF2 ADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007080.1|UniProtKB=W5MJL1 W5MJL1 PTHR13773:SF16 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 1 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008744.1|UniProtKB=W5MQJ3 W5MQJ3 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004948.1|UniProtKB=W5MC43 W5MC43 PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013799.1|UniProtKB=W5N8Q5 W5N8Q5 PTHR10159:SF305 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000000716.1|UniProtKB=W5LXE0 W5LXE0 PTHR14948:SF21 NG5 PROLINE-RICH TRANSMEMBRANE PROTEIN 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001236.1|UniProtKB=W5LZ49 W5LZ49 PTHR22684:SF0 NULP1-RELATED RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000005700.1|UniProtKB=W5MES3 W5MES3 PTHR15111:SF0 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 molecular adaptor activity#GO:0060090;phosphatase regulator activity#GO:0019208;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;molecular function regulator activity#GO:0098772;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;protein-containing complex binding#GO:0044877;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of dephosphorylation#GO:0035303;regulation of RNA biosynthetic process#GO:2001141;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of hydrolase activity#GO:0051336;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of phosphorus metabolic process#GO:0010563;regulation of phosphatase activity#GO:0010921;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004668.1|UniProtKB=W5MB33 W5MB33 PTHR12902:SF6 WASP-1 ACTIN-BINDING PROTEIN WASF2 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 cell leading edge#GO:0031252;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000010467.1|UniProtKB=W5MWS0 W5MWS0 PTHR10073:SF47 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH3 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015304.1|UniProtKB=W5NDX1 W5NDX1 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000113.1|UniProtKB=W5LVG8 W5LVG8 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000009529.1|UniProtKB=W5MTE4 W5MTE4 PTHR14514:SF2 PKA ANCHORING PROTEIN A-KINASE ANCHOR PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000008862.1|UniProtKB=W5MQX8 W5MQX8 PTHR14191:SF6 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF3-RELATED protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010484.1|UniProtKB=W5MWU1 W5MWU1 PTHR11471:SF33 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;signaling#GO:0023052;positive regulation of biological process#GO:0048518 intercellular signal molecule#PC00207 FAS signaling pathway#P00020>FasL#P00617;Apoptosis signaling pathway#P00006>FAS ligand#P00326 LEPOC|Ensembl=ENSLOCG00000003594.1|UniProtKB=W5M7A1 W5M7A1 B3GALNT1 PTHR11214:SF153 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009909.1|UniProtKB=W5MUQ0 W5MUQ0 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000013259.1|UniProtKB=W5N6T4 W5N6T4 PTHR11036:SF65 SEMAPHORIN SEMAPHORIN-6D molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;axon guidance#GO:0007411;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell communication#GO:0007154;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004898.1|UniProtKB=W5MBX3 W5MBX3 PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003229.1|UniProtKB=W5M603 W5M603 PTHR20939:SF10 SORTING NEXIN 20, 21 SORTING NEXIN-21 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012307.1|UniProtKB=W5N3D1 W5N3D1 PTHR11360:SF27 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 4 secondary active monocarboxylate transmembrane transporter activity#GO:0015355;solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017290.1|UniProtKB=W5NL81 W5NL81 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012048.1|UniProtKB=W5N2G2 W5N2G2 PTHR10075:SF23 BASIGIN RELATED MYOTILIN cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007650.1|UniProtKB=W5MLM0 W5MLM0 PTPRC PTHR19134:SF539 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;negative regulation of protein kinase activity#GO:0006469;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;negative regulation of phosphorus metabolic process#GO:0010563;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of phosphorus metabolic process#GO:0010562;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 protein phosphatase#PC00195;protein modifying enzyme#PC00260 T cell activation#P00053>CD45#P01329;JAK/STAT signaling pathway#P00038>PTP#P01033;B cell activation#P00010>CD45#P00396 LEPOC|Ensembl=ENSLOCG00000006070.1|UniProtKB=W5MG20 W5MG20 PTHR20917:SF0 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012910.1|UniProtKB=W5N5I5 W5N5I5 PTHR24365:SF422 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000011248.1|UniProtKB=W5MZM8 W5MZM8 PTHR12287:SF22 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of signal transduction#GO:0009966;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012345.1|UniProtKB=W5N3I8 W5N3I8 PTHR24271:SF96 KALLIKREIN-RELATED GRANZYME A-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003204.1|UniProtKB=W5M5X9 W5M5X9 PTHR24061:SF581 CALCIUM-SENSING RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016459.1|UniProtKB=W5NI72 W5NI72 OXER1 PTHR46048:SF10 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 1-4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007219.1|UniProtKB=W5MK27 W5MK27 PTHR13968:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN RALY nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015681.1|UniProtKB=W5NF94 W5NF94 PTHR11693:SF22 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>F1 gamma#P02796 LEPOC|Ensembl=ENSLOCG00000008923.1|UniProtKB=W5MR63 W5MR63 PTHR24300:SF326 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010570.1|UniProtKB=W5MX40 W5MX40 PTHR11309:SF150 FRIZZLED FRIZZLED CLASS RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003239.1|UniProtKB=W5M617 W5M617 PTHR12011:SF454 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G5-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005149.1|UniProtKB=W5MCU0 W5MCU0 PTHR12479:SF2 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 5 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011652.1|UniProtKB=W5N115 W5N115 BTRC PTHR14604:SF5 WD40 REPEAT PF20 F-BOX_WD REPEAT-CONTAINING PROTEIN 1A microtubule or microtubule-binding cytoskeletal protein#PC00157 Hedgehog signaling pathway#P00025>Slimb#P00683;Wnt signaling pathway#P00057>betaTrCP#P01454 LEPOC|Ensembl=ENSLOCG00000008375.1|UniProtKB=W5MP74 W5MP74 PTHR10454:SF210 CASPASE CASPASE-2 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003660.1|UniProtKB=W5M7I9 W5M7I9 PTHR10026:SF42 CYCLIN CYCLIN-T1 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000018172.1|UniProtKB=W5NNR4 W5NNR4 PTHR12887:SF13 NANOS PROTEIN NANOS HOMOLOG 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;oogenesis#GO:0048477;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002429.1|UniProtKB=W5M3A7 W5M3A7 PTHR10372:SF5 PLAKOPHILLIN-RELATED SPLICING REGULATOR ARVCF cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000004131.1|UniProtKB=W5M987 W5M987 PTHR24006:SF902 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009662.1|UniProtKB=W5MTU9 W5MTU9 LGR6 PTHR24372:SF73 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE RICH REPEAT CONTAINING G PROTEIN-COUPLED RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015381.1|UniProtKB=W5NE68 W5NE68 PTHR11471:SF55 TUMOR NECROSIS FACTOR FAMILY MEMBER DEATH LIGAND 3 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000006427.1|UniProtKB=W5MHA6 W5MHA6 PTHR19143:SF40 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 7 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007335.1|UniProtKB=W5MKH5 W5MKH5 PTHR23503:SF27 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 2 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 brush border#GO:0005903;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cluster of actin-based cell projections#GO:0098862;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012578.1|UniProtKB=W5N4C3 W5N4C3 PTHR11964:SF11 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 LEPOC|Ensembl=ENSLOCG00000002665.1|UniProtKB=W5M434 W5M434 PTHR13112:SF2 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3A sequence-specific DNA binding#GO:0043565;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;mRNA binding#GO:0003729 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of amide metabolic process#GO:0034248;RNA metabolic process#GO:0016070;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;positive regulation of protein metabolic process#GO:0051247;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010761.1|UniProtKB=W5MXT0 W5MXT0 PTHR11964:SF38 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000013372.1|UniProtKB=W5N772 W5N772 PTHR48051:SF64 FAMILY NOT NAMED LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007942.1|UniProtKB=W5MMP6 W5MMP6 PTHR10372:SF6 PLAKOPHILLIN-RELATED CATENIN DELTA-1 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 Cadherin signaling pathway#P00012>P120#P00473 LEPOC|Ensembl=ENSLOCG00000007894.1|UniProtKB=W5MMI5 W5MMI5 PTHR24412:SF155 KELCH PROTEIN KELCH-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013749.1|UniProtKB=W5N8K0 W5N8K0 PTHR31399:SF0 DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN catalytic activity, acting on RNA#GO:0140098;DNA-directed DNA polymerase activity#GO:0003887;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;RNA polymerase activity#GO:0097747;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;mitochondrion organization#GO:0007005;replication fork processing#GO:0031297;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial genome maintenance#GO:0000002;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;translesion synthesis#GO:0019985;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;mitochondrial DNA metabolic process#GO:0032042;organelle organization#GO:0006996;response to UV#GO:0009411;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003693.1|UniProtKB=W5M7M7 W5M7M7 PTHR20426:SF0 RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG 18S RRNA AMINOCARBOXYPROPYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000009007.1|UniProtKB=W5MRG3 W5MRG3 PTHR22763:SF163 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF139 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007648.1|UniProtKB=W5MLL9 W5MLL9 PTHR11955:SF74 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 5 fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000017058.1|UniProtKB=W5NKB9 W5NKB9 PTHR46532:SF13 MALE FERTILITY FACTOR KL5 CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000017057.1|UniProtKB=W5NKB8 W5NKB8 PTHR15742:SF2 GIRDIN PROTEIN SOGA3 LEPOC|Ensembl=ENSLOCG00000002899.1|UniProtKB=W5M4W8 W5M4W8 PTHR11584:SF391 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6 MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>MEKK1-5#P00634 LEPOC|Ensembl=ENSLOCG00000008052.1|UniProtKB=W5MN19 W5MN19 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BARDET-BIEDL SYNDROME 5 PROTEIN phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;BBSome#GO:0034464;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000002251.1|UniProtKB=W5M2L6 W5M2L6 PTHR24100:SF145 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009790.1|UniProtKB=W5MUA7 W5MUA7 PTHR14196:SF4 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009495.1|UniProtKB=W5MT88 W5MT88 PTHR10127:SF791 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009793.1|UniProtKB=W5MUB3 W5MUB3 MAP3K13 PTHR23257:SF945 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13-A transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011287.1|UniProtKB=W5MZR7 W5MZR7 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010096.1|UniProtKB=W5MVE3 W5MVE3 PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 LEPOC|Ensembl=ENSLOCG00000017843.1|UniProtKB=W5NMT7 W5NMT7 PTHR24225:SF74 CHEMOTACTIC RECEPTOR CHEMOKINE-LIKE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015644.1|UniProtKB=W5NF50 W5NF50 PTHR46006:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008758.1|UniProtKB=W5MQJ8 W5MQJ8 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013663.1|UniProtKB=W5N886 W5N886 PTHR11486:SF27 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 16 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000010624.1|UniProtKB=W5MXD5 W5MXD5 PTHR24023:SF1034 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000013868.1|UniProtKB=W5N8Z7 W5N8Z7 PTHR12928:SF0 FRG1 PROTEIN FSHD REGION GENE 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018093.1|UniProtKB=W5NNI5 W5NNI5 PTHR24229:SF20 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 5 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular response to steroid hormone stimulus#GO:0071383;regulation of signaling#GO:0023051;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of peptide secretion#GO:0002791;cellular response to hormone stimulus#GO:0032870;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;neuropeptide signaling pathway#GO:0007218;regulation of hormone secretion#GO:0046883;cellular response to organic cyclic compound#GO:0071407;regulation of protein transport#GO:0051223;signaling#GO:0023052;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;regulation of hormone levels#GO:0010817;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of establishment of protein localization#GO:0070201;response to steroid hormone#GO:0048545;regulation of peptide transport#GO:0090087 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000002663.1|UniProtKB=W5M422 W5M422 PTHR31396:SF2 PROTEIN FAM163B MEMBER PROTEIN FAM163B LEPOC|Ensembl=ENSLOCG00000001527.1|UniProtKB=W5M039 W5M039 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017222.1|UniProtKB=W5NKY9 W5NKY9 PTHR12877:SF14 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;positive regulation of organelle organization#GO:0010638;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;mitotic cell cycle#GO:0000278;positive regulation of actin filament bundle assembly#GO:0032233;actin filament-based process#GO:0030029;regulation of cellular component biogenesis#GO:0044087;mitotic spindle assembly#GO:0090307;regulation of actin cytoskeleton organization#GO:0032956;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;regulation of actin filament-based process#GO:0032970;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;positive regulation of cellular component biogenesis#GO:0044089;non-membrane-bounded organelle assembly#GO:0140694;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;organelle fission#GO:0048285;actin cytoskeleton organization#GO:0030036;regulation of actin filament bundle assembly#GO:0032231 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000008546.1|UniProtKB=W5MPU3 W5MPU3 PTHR10869:SF101 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006578.1|UniProtKB=W5MHT6 W5MHT6 PTHR45775:SF2 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;transporter regulator activity#GO:0141108;anion binding#GO:0043168;channel regulator activity#GO:0016247;ion binding#GO:0043167 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016271.1|UniProtKB=W5NHF8 W5NHF8 PTHR14869:SF0 MYC TARGET PROTEIN 1 MYC TARGET PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000504.1|UniProtKB=W5LWQ2 W5LWQ2 PTHR22891:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;pre-miRNA processing#GO:0031054;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000004797.1|UniProtKB=W5MBN6 W5MBN6 BTBD8 PTHR22427:SF2 GH15728P BTB_POZ DOMAIN-CONTAINING PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000015287.1|UniProtKB=W5NDV0 W5NDV0 PTHR22883:SF71 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC9 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006545.1|UniProtKB=W5MHP9 W5MHP9 PTHR10217:SF380 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 8 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017551.1|UniProtKB=W5NLZ7 W5NLZ7 PTHR24241:SF127 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 22-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015072.1|UniProtKB=W5ND41 W5ND41 PTHR12905:SF31 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN 1 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000009787.1|UniProtKB=W5MUA3 W5MUA3 PTHR12027:SF92 WNT RELATED PROTEIN WNT-8A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000005537.1|UniProtKB=W5ME75 W5ME75 PTHR14066:SF10 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;circulatory system process#GO:0003013;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cGMP biosynthetic process#GO:0006182;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;blood circulation#GO:0008015;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;neuropeptide signaling pathway#GO:0007218;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;regulation of systemic arterial blood pressure#GO:0003073;cellular biosynthetic process#GO:0044249;cGMP-mediated signaling#GO:0019934;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of blood pressure#GO:0008217;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935;purine ribonucleotide biosynthetic process#GO:0009152 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010759.1|UniProtKB=W5MXT9 W5MXT9 PTHR13258:SF0 SYNDETIN SYNDETIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013507.1|UniProtKB=W5N7P5 W5N7P5 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000003354.1|UniProtKB=W5M6G6 W5M6G6 PTHR14429:SF24 FIBROSIN FAMILY MEMBER FIBROSIN LEPOC|Ensembl=ENSLOCG00000013561.1|UniProtKB=W5N7W6 W5N7W6 PTHR10404:SF33 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824 inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;metal ion transport#GO:0030001;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;intracellular iron ion homeostasis#GO:0006879;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;establishment of localization in cell#GO:0051649;transition metal ion transport#GO:0000041;receptor-mediated endocytosis#GO:0006898;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006180.1|UniProtKB=W5MGF6 W5MGF6 PTHR10780:SF20 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 2 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008795.1|UniProtKB=W5MQQ1 W5MQQ1 PTHR13856:SF31 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 2 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010127.1|UniProtKB=W5MVJ4 W5MVJ4 PTHR14131:SF6 ANOSMIN ANOSMIN-1-RELATED cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008917.1|UniProtKB=W5MR50 W5MR50 PTHR35352:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 LEPOC|Ensembl=ENSLOCG00000011391.1|UniProtKB=W5N048 W5N048 PTHR13763:SF0 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;double-strand break repair#GO:0006302;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;recombinational repair#GO:0000725;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;BRCA1-A complex#GO:0070531;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004864.1|UniProtKB=W5MBT6 W5MBT6 PTHR24300:SF395 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002228.1|UniProtKB=W5M2I6 W5M2I6 PTHR11349:SF54 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 LEPOC|Ensembl=ENSLOCG00000008023.1|UniProtKB=W5MMY8 W5MMY8 NUP98 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000394.1|UniProtKB=W5LWC7 W5LWC7 PTHR45831:SF3 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN ALPHA localization within membrane#GO:0051668;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009255.1|UniProtKB=W5MSC9 W5MSC9 PTHR12729:SF6 TRNA(HIS) GUANYLYLTRANSFERASE-RELATED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000010051.1|UniProtKB=W5MV89 W5MV89 UHRF2 PTHR14140:SF3 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;primary metabolic process#GO:0044238;epigenetic regulation of gene expression#GO:0040029;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012681.1|UniProtKB=W5N4P3 W5N4P3 PTHR31508:SF2 PROTEIN PITCHFORK PROTEIN PITCHFORK cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344 LEPOC|Ensembl=ENSLOCG00000004345.1|UniProtKB=W5M9Y6 W5M9Y6 PTHR43489:SF6 ISOMERASE HYDROXYPYRUVATE ISOMERASE-RELATED isomerase activity#GO:0016853;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007597.1|UniProtKB=W5MLF7 W5MLF7 PTHR23292:SF7 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR CELL DEATH-INDUCING P53-TARGET PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cell communication#GO:0007154;signal transduction by p53 class mediator#GO:0072331;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;DNA damage response#GO:0006974;response to stress#GO:0006950;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010302.1|UniProtKB=W5MW61 W5MW61 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein-containing complex assembly#GO:0065003;protein targeting#GO:0006605;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016562.1|UniProtKB=W5NIJ6 W5NIJ6 PTHR16770:SF3 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY2 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006132.1|UniProtKB=W5MGA1 W5MGA1 PTHR16134:SF5 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 3 regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;response to radiation#GO:0009314;biological regulation#GO:0065007;response to abiotic stimulus#GO:0009628;regulation of circadian rhythm#GO:0042752 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008064.1|UniProtKB=W5MN32 W5MN32 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017047.1|UniProtKB=W5NKA7 W5NKA7 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB_POZ DOMAIN-CONTAINING PROTEIN 9 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009666.1|UniProtKB=W5MTV6 W5MTV6 PTHR23506:SF30 GH10249P SYNAPTIC VESICULAR AMINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;neurotransmitter transport#GO:0006836;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 secondary carrier transporter#PC00258;transporter#PC00227 Nicotine pharmacodynamics pathway#P06587>SLC18A2#P06604;Dopamine receptor mediated signaling pathway#P05912>VAT2#P05960;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;Adrenaline and noradrenaline biosynthesis#P00001>VAT2#P00070;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;CCKR signaling map#P06959>VMAT2#G07295;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;CCKR signaling map#P06959>VMAT2#P07137;CCKR signaling map#P06959>VMAT2#G07002 LEPOC|Ensembl=ENSLOCG00000010135.1|UniProtKB=W5MVJ3 W5MVJ3 PTHR23430:SF20 HISTONE H2A CORE HISTONE MACRO-H2A.1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;heterochromatin formation#GO:0031507;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of transcription by RNA polymerase I#GO:0006356;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018343.1|UniProtKB=W5NP85 W5NP85 PTHR13832:SF627 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 1, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000134.1|UniProtKB=W5LVI8 W5LVI8 PTHR24027:SF438 CADHERIN-23 CADHERIN 23 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;multicellular organismal process#GO:0032501;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular process#GO:0009987;cell migration#GO:0016477 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000010811.1|UniProtKB=W5MXZ3 W5MXZ3 PTHR48083:SF6 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE 6 nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010763.1|UniProtKB=W5MXT8 W5MXT8 PTHR10050:SF46 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 2 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000078.1|UniProtKB=W5LVD2 W5LVD2 PTHR19300:SF5 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 1 cytoskeletal protein binding#GO:0008092;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;protein binding#GO:0005515;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015102.1|UniProtKB=W5ND80 W5ND80 PTHR10997:SF26 IMPORTIN-7, 8, 11 IMPORTIN-8 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007984.1|UniProtKB=W5MMU9 W5MMU9 PTHR13906:SF16 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane#GO:0044233 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006826.1|UniProtKB=W5MIP5 W5MIP5 PTHR45879:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>ATF1#P06019 LEPOC|Ensembl=ENSLOCG00000011503.1|UniProtKB=W5N0K2 W5N0K2 PTHR45703:SF12 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 11 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000010269.1|UniProtKB=W5MW16 W5MW16 PTHR12484:SF4 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A LEPOC|Ensembl=ENSLOCG00000009166.1|UniProtKB=W5MS46 W5MS46 PTHR22826:SF115 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012154.1|UniProtKB=W5N2T9 W5N2T9 PTHR45752:SF48 LEUCINE-RICH REPEAT-CONTAINING MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008976.1|UniProtKB=W5MRC5 W5MRC5 PYROXD2 PTHR10668:SF103 PHYTOENE DEHYDROGENASE PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005504.1|UniProtKB=W5ME32 W5ME32 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012949.1|UniProtKB=W5N5P0 W5N5P0 PTHR46753:SF2 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of organelle organization#GO:0010638;regulation of catabolic process#GO:0009894;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;positive regulation of cellular catabolic process#GO:0031331;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;regulation of protein-containing complex disassembly#GO:0043244;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;transport along microtubule#GO:0010970;positive regulation of cellular process#GO:0048522;localization#GO:0051179;microtubule-based transport#GO:0099111;positive regulation of macroautophagy#GO:0016239;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of cellular component organization#GO:0051130;establishment of localization in cell#GO:0051649;positive regulation of autophagy#GO:0010508;intracellular transport#GO:0046907;regulation of autophagosome maturation#GO:1901096;organelle transport along microtubule#GO:0072384;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;vesicle cytoskeletal trafficking#GO:0099518 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000004975.1|UniProtKB=W5MC78 W5MC78 UBE2R2 PTHR24067:SF148 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012443.1|UniProtKB=W5N3V7 W5N3V7 PTHR46839:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 6 SUSHI DOMAIN-CONTAINING 6 response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 LEPOC|Ensembl=ENSLOCG00000009806.1|UniProtKB=W5MUC8 W5MUC8 PTHR13800:SF2 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013985.1|UniProtKB=W5N9C9 W5N9C9 PTHR23002:SF117 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN CCHC-TYPE ZINC FINGER, NUCLEIC ACID-BINDING PROTEIN A-RELATED nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002421.1|UniProtKB=W5M384 W5M384 PTHR11588:SF429 TUBULIN TUBULIN BETA 8B-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 LEPOC|Ensembl=ENSLOCG00000010668.1|UniProtKB=W5MXJ6 W5MXJ6 PTHR10037:SF137 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;positive regulation of secretion#GO:0051047;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;action potential#GO:0001508;regulation of localization#GO:0032879;calcium ion transport#GO:0006816;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Nicotine pharmacodynamics pathway#P06587>CACNA#P06600;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;GABA-B receptor II signaling#P05731>Ca channel#P05753 LEPOC|Ensembl=ENSLOCG00000001305.1|UniProtKB=W5LZC5 W5LZC5 PTHR46239:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C DNA REPAIR PROTEIN RAD51 HOMOLOG 3 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;four-way junction DNA binding#GO:0000400 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007869.1|UniProtKB=W5MME9 W5MME9 PTHR46256:SF1 AGAP011099-PA MYOSIN-IIIB microfilament motor activity#GO:0000146;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;cytoskeletal motor activity#GO:0003774;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of plasma membrane bounded cell projection assembly#GO:0120032;macromolecule modification#GO:0043412;sensory perception of sound#GO:0007605;system process#GO:0003008;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;phosphorylation#GO:0016310;positive regulation of cellular component biogenesis#GO:0044089;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nervous system process#GO:0050877;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;sensory perception of mechanical stimulus#GO:0050954;regulation of filopodium assembly#GO:0051489;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;peptidyl-serine modification#GO:0018209;multicellular organismal process#GO:0032501;sensory perception#GO:0007600 stereocilium#GO:0032420;stereocilium bundle#GO:0032421;cluster of actin-based cell projections#GO:0098862;filopodium#GO:0030175;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;photoreceptor inner segment#GO:0001917;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000017946.1|UniProtKB=W5NN40 W5NN40 PTHR10489:SF935 CELL ADHESION MOLECULE RELAXIN FAMILY PEPTIDE RECEPTOR 3.3A1-RELATED signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015045.1|UniProtKB=W5ND07 W5ND07 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016615.1|UniProtKB=W5NIR6 W5NIR6 PTHR23069:SF5 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;nucleosome assembly#GO:0006334;RNA metabolic process#GO:0016070;positive regulation of cellular metabolic process#GO:0031325;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;protein-containing complex disassembly#GO:0032984;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;epigenetic regulation of gene expression#GO:0040029;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018337.1|UniProtKB=W5NP79 W5NP79 PTHR46280:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 cellular localization#GO:0051641;vacuolar transport#GO:0007034;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011281.1|UniProtKB=W5MZQ5 W5MZQ5 PTHR43015:SF1 D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008330.1|UniProtKB=W5MP21 W5MP21 PTHR12385:SF34 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016402.1|UniProtKB=W5NHZ5 W5NHZ5 RNF8 PTHR15067:SF4 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE RNF8 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006871.1|UniProtKB=W5MIV2 W5MIV2 PTHR45917:SF1 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 1 transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015630.1|UniProtKB=W5NF37 W5NF37 PTHR11119:SF33 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 2 oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009853.1|UniProtKB=W5MUI5 W5MUI5 PTHR12479:SF6 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009136.1|UniProtKB=W5MRX8 W5MRX8 PTHR11949:SF50 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010511.1|UniProtKB=W5MWY2 W5MWY2 PTHR24058:SF43 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;signal transduction by p53 class mediator#GO:0072331;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;cellular response to stimulus#GO:0051716;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;peptidyl-threonine phosphorylation#GO:0018107;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;PML body#GO:0016605;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010213.1|UniProtKB=W5MVU5 W5MVU5 PTHR11515:SF14 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA-5 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000002467.1|UniProtKB=W5M3D6 W5M3D6 PTHR24393:SF151 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017397.1|UniProtKB=W5NLJ3 W5NLJ3 PTHR24232:SF44 G-PROTEIN COUPLED RECEPTOR URACIL NUCLEOTIDE_CYSTEINYL LEUKOTRIENE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011896.1|UniProtKB=W5N1X1 W5N1X1 PTHR15021:SF2 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018026.1|UniProtKB=W5NNB8 W5NNB8 PTHR34072:SF52 ENZYMATIC POLYPROTEIN-RELATED RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000017160.1|UniProtKB=W5NKQ2 W5NKQ2 PTHR28598:SF1 STAGA COMPLEX 65 SUBUNIT GAMMA STAGA COMPLEX 65 SUBUNIT GAMMA transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 LEPOC|Ensembl=ENSLOCG00000004578.1|UniProtKB=W5MAS4 W5MAS4 PTHR45636:SF44 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX 10-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002820.1|UniProtKB=W5M4N7 W5M4N7 PTHR13217:SF11 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 LEPOC|Ensembl=ENSLOCG00000004186.1|UniProtKB=W5M9D9 W5M9D9 NAAA PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012118.1|UniProtKB=W5N2Q3 W5N2Q3 PTHR14588:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 10 DDB1- AND CUL4-ASSOCIATED FACTOR 10 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000016793.1|UniProtKB=W5NJE7 W5NJE7 PTHR12121:SF27 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL HOMOLOG 2 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;mRNA 3'-UTR binding#GO:0003730;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;mRNA binding#GO:0003729;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000015744.1|UniProtKB=W5NFH0 W5NFH0 PTHR11021:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000015425.1|UniProtKB=W5NEC4 W5NEC4 PTHR13367:SF3 UBIQUITIN THIOESTERASE TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;protein modification by small protein removal#GO:0070646;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;cell migration#GO:0016477 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>A20#P01348 LEPOC|Ensembl=ENSLOCG00000013493.1|UniProtKB=W5N7M7 W5N7M7 PTHR12806:SF0 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000005584.1|UniProtKB=W5MED2 W5MED2 VSTM2B PTHR12207:SF27 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2B cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000472.1|UniProtKB=W5LWL1 W5LWL1 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000433.1|UniProtKB=W5LWG8 W5LWG8 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1 BETA CHAIN major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000014961.1|UniProtKB=W5NCR0 W5NCR0 PTHR24248:SF3 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-3 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of blood pressure#GO:0045776;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of systemic arterial blood pressure#GO:0003073;cellular process#GO:0009987;circulatory system process#GO:0003013;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of blood pressure#GO:0008217;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Beta3 adrenergic receptor signaling pathway#P04379>Beta3#P04449;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000000070.1|UniProtKB=W5LVC3 W5LVC3 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000008343.1|UniProtKB=W5MP22 W5MP22 PTHR14571:SF13 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 13 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014728.1|UniProtKB=W5NBX5 W5NBX5 PTHR14939:SF5 F-BOX ONLY PROTEIN 22 F-BOX ONLY PROTEIN 22 LEPOC|Ensembl=ENSLOCG00000007957.1|UniProtKB=W5MMQ9 W5MMQ9 ASNA1 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014622.1|UniProtKB=W5NBI6 W5NBI6 PTHR45532:SF4 WD REPEAT-CONTAINING PROTEIN 97 WD REPEAT-CONTAINING PROTEIN 55 HOMOLOG LEPOC|Ensembl=ENSLOCG00000007670.1|UniProtKB=W5MLP8 W5MLP8 PTHR24086:SF49 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NR5A2 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014132.1|UniProtKB=W5N9V3 W5N9V3 PTHR19321:SF1 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;spindle elongation#GO:0051231;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;spindle midzone#GO:0051233;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000003724.1|UniProtKB=W5M7T5 W5M7T5 PTHR23503:SF51 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 response to organic substance#GO:0010033;response to insulin#GO:0032868;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;response to peptide hormone#GO:0043434;organic anion transport#GO:0015711;transport#GO:0006810;glucose transmembrane transport#GO:1904659;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to chemical#GO:0042221;establishment of localization#GO:0051234;response to peptide#GO:1901652;vitamin transport#GO:0051180 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06890;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#P06724;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06675 LEPOC|Ensembl=ENSLOCG00000001587.1|UniProtKB=W5M0C4 W5M0C4 PTHR13326:SF21 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE PUS7L isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000005115.1|UniProtKB=W5MCR3 W5MCR3 PTHR24023:SF58 COLLAGEN ALPHA COLLAGEN ALPHA-1(II) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000014252.1|UniProtKB=W5NAA0 W5NAA0 PTHR10166:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014461.1|UniProtKB=W5NAY9 W5NAY9 PTHR31199:SF1 ARPIN ARPIN negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of cellular process#GO:0048523 LEPOC|Ensembl=ENSLOCG00000003469.1|UniProtKB=W5M6W0 W5M6W0 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin binding#GO:0043130 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;RNA localization#GO:0006403;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;chromosome organization#GO:0051276;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006567.1|UniProtKB=W5MHR9 W5MHR9 PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000015597.1|UniProtKB=W5NEZ5 W5NEZ5 PTHR10844:SF18 CAVEOLIN CAVEOLIN-1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;transmembrane transporter binding#GO:0044325;binding#GO:0005488;kinase binding#GO:0019900 inorganic ion homeostasis#GO:0098771;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;regulation of cell population proliferation#GO:0042127;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;developmental process#GO:0032502;endomembrane system organization#GO:0010256;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular component organization#GO:0016043;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;regulation of cytosolic calcium ion concentration#GO:0051480;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;membrane assembly#GO:0071709;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of cellular process#GO:0048523 plasma membrane raft#GO:0044853;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;Golgi apparatus#GO:0005794;cell junction#GO:0030054;caveola#GO:0005901;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;membrane raft#GO:0045121;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Caveolin#P00918;Gonadotropin-releasing hormone receptor pathway#P06664>Caveolin-1#P06763 LEPOC|Ensembl=ENSLOCG00000008505.1|UniProtKB=W5MPP2 W5MPP2 PTHR14453:SF94 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP10 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011983.1|UniProtKB=W5N286 W5N286 PTHR45718:SF5 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTIONAL ACTIVATOR GLI3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cell communication#GO:0007154;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690;Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687 LEPOC|Ensembl=ENSLOCG00000001532.1|UniProtKB=W5M0D1 W5M0D1 PTHR45727:SF2 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005194.1|UniProtKB=W5MCZ8 W5MCZ8 PTHR24082:SF38 NUCLEAR HORMONE RECEPTOR VITAMIN D3 RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Vitamin D metabolism and pathway#P04396>VDR#P04606 LEPOC|Ensembl=ENSLOCG00000013162.1|UniProtKB=W5N6F5 W5N6F5 PTHR11486:SF20 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 7 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of RNA biosynthetic process#GO:1902680;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;chemotaxis#GO:0006935;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000005983.1|UniProtKB=W5MFS4 W5MFS4 PTHR11732:SF488 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1-B oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009542.1|UniProtKB=W5MTF3 W5MTF3 PTHR23430:SF37 HISTONE H2A CORE HISTONE MACRO-H2A.2 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;heterochromatin formation#GO:0031507;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of transcription by RNA polymerase I#GO:0006356;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017104.1|UniProtKB=W5NKH6 W5NKH6 PTHR46690:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG aerobic respiration#GO:0009060;cellular component assembly#GO:0022607;cellular respiration#GO:0045333;cellular component biogenesis#GO:0044085;generation of precursor metabolites and energy#GO:0006091;protein-containing complex assembly#GO:0065003;electron transport chain#GO:0022900;cellular metabolic process#GO:0044237;ATP synthesis coupled electron transport#GO:0042773;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;respiratory electron transport chain#GO:0022904;cytochrome complex assembly#GO:0017004;oxidative phosphorylation#GO:0006119;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005524.1|UniProtKB=W5ME69 W5ME69 PTHR45734:SF1 TENSIN TENSIN-2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003769.1|UniProtKB=W5M7Y5 W5M7Y5 PTHR14958:SF12 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD5 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013127.1|UniProtKB=W5N6B5 W5N6B5 PTHR13530:SF3 TBC1 DOMAIN FAMILY MEMBER 7 TBC1 DOMAIN FAMILY MEMBER 7 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;activation of GTPase activity#GO:0090630;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;positive regulation of hydrolase activity#GO:0051345;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000010098.1|UniProtKB=W5MVF0 W5MVF0 PTHR24291:SF119 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 27C1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;cholesterol metabolic process#GO:0008203;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016329.1|UniProtKB=W5NHQ1 W5NHQ1 PTHR43612:SF3 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 LEPOC|Ensembl=ENSLOCG00000015001.1|UniProtKB=W5NCW1 W5NCW1 PTHR15813:SF8 SORTING NEXIN-22 AND 24 SORTING NEXIN-22 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010637.1|UniProtKB=W5MXD0 W5MXD0 PTHR46106:SF1 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE-LIKE N cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;regulation of localization#GO:0032879;peptide secretion#GO:0002790;cellular homeostasis#GO:0019725;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular response to oxygen-containing compound#GO:1901701;hormone secretion#GO:0046879;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;peptide hormone secretion#GO:0030072;signal release#GO:0023061;insulin secretion#GO:0030073;hormone transport#GO:0009914;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;cell communication#GO:0007154;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;regulation of hormone levels#GO:0010817;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;response to stimulus#GO:0050896;intracellular glucose homeostasis#GO:0001678;response to glucose#GO:0009749;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;carbohydrate homeostasis#GO:0033500 cytoplasm#GO:0005737;synapse#GO:0045202;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012669.1|UniProtKB=W5N4N0 W5N4N0 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009134.1|UniProtKB=W5MRX7 W5MRX7 PTHR42757:SF43 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OBSCURIN, CYTOSKELETAL CALMODULIN AND TITIN-INTERACTING RHOGEF B defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017333.1|UniProtKB=W5NLC9 W5NLC9 PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 LEPOC|Ensembl=ENSLOCG00000012332.1|UniProtKB=W5N3G8 W5N3G8 PTHR15117:SF5 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000009512.1|UniProtKB=W5MTC3 W5MTC3 NPAS3 PTHR23043:SF30 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004051.1|UniProtKB=W5M8X3 W5M8X3 PTHR11455:SF18 CRYPTOCHROME SI:CH1073-390K14.1 nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deoxyribodipyrimidine photo-lyase activity#GO:0003904;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167 response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505 LEPOC|Ensembl=ENSLOCG00000016652.1|UniProtKB=W5NIW2 W5NIW2 PTHR12381:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U RNA binding#GO:0003723;nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;mRNA metabolic process#GO:0016071;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;positive regulation of RNA metabolic process#GO:0051254;RNA splicing, via transesterification reactions#GO:0000375;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017172.1|UniProtKB=W5NKR6 W5NKR6 PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012509.1|UniProtKB=W5N442 W5N442 PTHR31888:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 19 SMALL INTEGRAL MEMBRANE PROTEIN 19 LEPOC|Ensembl=ENSLOCG00000016134.1|UniProtKB=W5NGX1 W5NGX1 PTHR45704:SF9 RAS-LIKE FAMILY MEMBER 11 RERG_RAS-LIKE LEPOC|Ensembl=ENSLOCG00000006323.1|UniProtKB=W5MGY2 W5MGY2 NUP214 PTHR23193:SF21 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP214 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004472.1|UniProtKB=W5MAD8 W5MAD8 PTHR20852:SF45 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 LEPOC|Ensembl=ENSLOCG00000016488.1|UniProtKB=W5NIA9 W5NIA9 PTHR10127:SF828 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012257.1|UniProtKB=W5N373 W5N373 PTHR31353:SF11 FAM98 PROTEIN FAM98B intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009354.1|UniProtKB=W5MSS6 W5MSS6 PTHR11771:SF5 LIPOXYGENASE POLYUNSATURATED FATTY ACID 5-LIPOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;icosanoid metabolic process#GO:0006690;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016408.1|UniProtKB=W5NI03 W5NI03 PTHR47007:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 4 SUSHI DOMAIN-CONTAINING PROTEIN 4 negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of innate immune response#GO:0045824;negative regulation of response to stimulus#GO:0048585;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;negative regulation of defense response#GO:0031348;regulation of response to biotic stimulus#GO:0002831;regulation of biological process#GO:0050789;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of immune effector process#GO:0002697;regulation of complement activation#GO:0030449;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of response to external stimulus#GO:0032102;regulation of immune system process#GO:0002682;negative regulation of immune system process#GO:0002683 LEPOC|Ensembl=ENSLOCG00000003957.1|UniProtKB=W5M8L9 W5M8L9 NUP54 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 localization within membrane#GO:0051668;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001021.1|UniProtKB=W5LYD8 W5LYD8 PTHR34605:SF3 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN P CELL-TYPE AGGLUTINATION PROTEIN MAP4-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000003576.1|UniProtKB=W5M784 W5M784 PTHR13832:SF827 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1L macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006269.1|UniProtKB=W5MGR4 W5MGR4 PTHR31037:SF2 RELT-LIKE PROTEIN 1-RELATED RELT TNF RECEPTOR regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007573.1|UniProtKB=W5MLC9 W5MLC9 PTHR24388:SF60 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018280.1|UniProtKB=W5NP22 W5NP22 PTHR31815:SF3 AGAP005329-PA TRANSMEMBRANE PROTEIN 200B LEPOC|Ensembl=ENSLOCG00000015462.1|UniProtKB=W5NEH0 W5NEH0 PTHR15682:SF2 UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012301.1|UniProtKB=W5N3C9 W5N3C9 PTHR48051:SF33 FAMILY NOT NAMED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017981.1|UniProtKB=W5NN73 W5NN73 PTHR32358:SF1 TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;cell activation involved in immune response#GO:0002263;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010139.1|UniProtKB=W5MVK2 W5MVK2 TAFA4 PTHR31770:SF7 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-4 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000009417.1|UniProtKB=W5MSX7 W5MSX7 PTTG1IP PTHR15191:SF7 PROTEIN CBG20567 PTTG1-INTERACTING PROTEIN B cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014171.1|UniProtKB=W5N9Z8 W5N9Z8 AXL PTHR24416:SF323 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR UFO signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;phagocytosis#GO:0006909;endocytosis#GO:0006897;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;regulation of body fluid levels#GO:0050878;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to wounding#GO:0009611;positive regulation of phosphate metabolic process#GO:0045937;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;import into cell#GO:0098657;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;mononuclear cell differentiation#GO:1903131;platelet activation#GO:0030168;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;positive regulation of molecular function#GO:0044093;wound healing#GO:0042060;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;hemopoiesis#GO:0030097;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;lymphocyte activation#GO:0046649;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell motility#GO:0048870;cellular process#GO:0009987;hemostasis#GO:0007599;negative regulation of apoptotic process#GO:0043066;coagulation#GO:0050817;localization#GO:0051179;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;lymphocyte differentiation#GO:0030098;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;blood coagulation#GO:0007596;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000816.1|UniProtKB=W5LXS9 W5LXS9 PTHR10379:SF13 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000018073.1|UniProtKB=W5NNG5 W5NNG5 PTHR45134:SF5 OS08G0543275 PROTEIN OS08G0543275 PROTEIN LEPOC|Ensembl=ENSLOCG00000007550.1|UniProtKB=W5MLA4 W5MLA4 PTHR43842:SF2 PROPIONYL-COA CARBOXYLASE BETA CHAIN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 LEPOC|Ensembl=ENSLOCG00000001341.1|UniProtKB=W5LZG7 W5LZG7 APIP PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000012838.1|UniProtKB=W5N596 W5N596 PTHR24126:SF3 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001366.1|UniProtKB=W5LZJ6 W5LZJ6 PTHR24204:SF7 INSULIN GENE ENHANCER PROTEIN LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;cell projection morphogenesis#GO:0048858;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007190.1|UniProtKB=W5MK00 W5MK00 PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996 cytoplasm#GO:0005737;endoplasmic reticulum tubular network#GO:0071782;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009908.1|UniProtKB=W5MUQ6 W5MUQ6 PTHR11547:SF23 ARGININE OR CREATINE KINASE CREATINE KINASE B-TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000004127.1|UniProtKB=W5M981 W5M981 PTHR14270:SF0 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000007908.1|UniProtKB=W5MMJ5 W5MMJ5 PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;Ras protein signal transduction#GO:0007265;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005025.1|UniProtKB=W5MCF5 W5MCF5 PTHR22692:SF21 MYOSIN VII, XV MYOSIN XVA actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000003652.1|UniProtKB=W5M7I1 W5M7I1 PTHR11042:SF72 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000435.1|UniProtKB=W5LWH0 W5LWH0 PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005421.1|UniProtKB=W5MDT3 W5MDT3 PTHR45686:SF10 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 vesicle targeting, to, from or within Golgi#GO:0048199;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;establishment of vesicle localization#GO:0051650;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;establishment of organelle localization#GO:0051656 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015095.1|UniProtKB=W5ND68 W5ND68 PTHR43648:SF1 ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000015761.1|UniProtKB=W5NFJ3 W5NFJ3 PTHR14467:SF0 ARV1 PROTEIN ARV1 sterol metabolic process#GO:0016125;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;sterol transport#GO:0015918;plasma membrane organization#GO:0007009;transport#GO:0006810;endomembrane system organization#GO:0010256;lipid transport#GO:0006869;sphingolipid metabolic process#GO:0006665;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;lipid localization#GO:0010876;intracellular lipid transport#GO:0032365;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;intracellular sterol transport#GO:0032366;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane lipid metabolic process#GO:0006643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;cortical endoplasmic reticulum#GO:0032541 LEPOC|Ensembl=ENSLOCG00000011011.1|UniProtKB=W5MYP9 W5MYP9 FAM53A PTHR28567:SF2 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53A cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016894.1|UniProtKB=W5NJT9 W5NJT9 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;regulation of transmembrane transport#GO:0034762;positive regulation of establishment of protein localization#GO:1904951;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;positive regulation of protein localization#GO:1903829;regulation of establishment of protein localization#GO:0070201 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015848.1|UniProtKB=W5NFV2 W5NFV2 PTHR15052:SF2 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 LEPOC|Ensembl=ENSLOCG00000001869.1|UniProtKB=W5M1A9 W5M1A9 PTHR15970:SF8 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 1 transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016529.1|UniProtKB=W5NIF5 W5NIF5 PTHR23137:SF24 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2A LEPOC|Ensembl=ENSLOCG00000012786.1|UniProtKB=W5N526 W5N526 STAC2 PTHR15135:SF5 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 2 regulation of metal ion transport#GO:0010959;system process#GO:0003008;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;skeletal muscle contraction#GO:0003009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of protein localization to membrane#GO:1905475;regulation of calcium ion transport#GO:0051924;positive regulation of transport#GO:0051050;nervous system process#GO:0050877;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;positive regulation of cellular process#GO:0048522;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of protein localization#GO:1903829;muscle system process#GO:0003012;muscle contraction#GO:0006936 LEPOC|Ensembl=ENSLOCG00000013020.1|UniProtKB=W5N5Y9 W5N5Y9 PTHR16154:SF24 NEURABIN NEURABIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 signal transduction#GO:0007165;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;cell projection organization#GO:0030030;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000012948.1|UniProtKB=W5N5N5 W5N5N5 PTHR10918:SF2 HOMER HOMER PROTEIN HOMOLOG 2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of metal ion transport#GO:0010959;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of monoatomic ion transport#GO:0043269;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012570.1|UniProtKB=W5N4C5 W5N4C5 PTHR45750:SF1 GH11602P HISTONE ACETYLTRANSFERASE KAT2A histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000013605.1|UniProtKB=W5N814 W5N814 PTHR10985:SF84 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008465.1|UniProtKB=W5MPJ5 W5MPJ5 PTHR22050:SF2 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131-LIKE cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017151.1|UniProtKB=W5NKN6 W5NKN6 METTL24 PTHR32026:SF20 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24 ISOFORM X1 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000013145.1|UniProtKB=W5N6D0 W5N6D0 PTHR12414:SF7 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMB sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016169.1|UniProtKB=W5NH14 W5NH14 PTHR10656:SF35 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE nucleic acid binding#GO:0003676;transferase activity#GO:0016740;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;DNA binding#GO:0003677;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 positive regulation of gene expression#GO:0010628;regulation of double-strand break repair#GO:2000779;positive regulation of type I interferon production#GO:0032481;activation of immune response#GO:0002253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;DNA damage response#GO:0006974;regulation of cellular response to stress#GO:0080135;positive regulation of cytokine production#GO:0001819;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of defense response#GO:0031349;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;negative regulation of DNA repair#GO:0045738;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to organic cyclic compound#GO:0071407;regulation of immune system process#GO:0002682;negative regulation of DNA recombination#GO:0045910;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;positive regulation of response to biotic stimulus#GO:0002833 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015941.1|UniProtKB=W5NG68 W5NG68 PTHR45776:SF1 MIP04163P TRANSCRIPTION FACTOR EC sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002339.1|UniProtKB=W5M2Y5 W5M2Y5 PTHR10827:SF98 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN calmodulin-related#PC00061 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 LEPOC|Ensembl=ENSLOCG00000012806.1|UniProtKB=W5N556 W5N556 PTHR15535:SF24 TRANSMEMBRANE PROTEIN 2-RELATED HYALURONOGLUCOSAMINIDASE LEPOC|Ensembl=ENSLOCG00000000649.1|UniProtKB=W5LX60 W5LX60 LRRC56 PTHR22708:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 LEPOC|Ensembl=ENSLOCG00000003357.1|UniProtKB=W5M6G1 W5M6G1 PTHR46943:SF1 PENTRAXIN-RELATED PROTEIN PTX3 PENTRAXIN-RELATED PROTEIN PTX3 LEPOC|Ensembl=ENSLOCG00000000188.1|UniProtKB=W5LVQ2 W5LVQ2 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002074.1|UniProtKB=W5M226 W5M226 PTHR24031:SF54 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000018110.1|UniProtKB=W5NNK2 W5NNK2 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002904.1|UniProtKB=W5M4V3 W5M4V3 PTHR46963:SF1 SIMILAR TO RIKEN CDNA E130308A19 SIMILAR TO RIKEN CDNA E130308A19 LEPOC|Ensembl=ENSLOCG00000017723.1|UniProtKB=W5NMG8 W5NMG8 PTHR24234:SF10 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012338.1|UniProtKB=W5N3I1 W5N3I1 PTHR10106:SF14 CYTOCHROME B561-RELATED TRANSMEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYB561 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008928.1|UniProtKB=W5MR62 W5MR62 PTHR14796:SF3 NEURENSIN 1-RELATED NEURENSIN 1-LIKE-RELATED multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;neuronal cell body#GO:0043025;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;cell body#GO:0044297;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000016339.1|UniProtKB=W5NHR1 W5NHR1 PTHR19282:SF527 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004840.1|UniProtKB=W5MBR4 W5MBR4 PTHR10502:SF29 ANNEXIN ANNEXIN A11 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 localization#GO:0051179;cell division#GO:0051301;establishment of localization#GO:0051234;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;cell cycle process#GO:0022402;cell cycle#GO:0007049;vesicle-mediated transport#GO:0016192;cytokinetic process#GO:0032506;cellular process#GO:0009987;cytokinesis#GO:0000910;import into cell#GO:0098657 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000003827.1|UniProtKB=W5M885 W5M885 PTHR48094:SF12 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PARKINSON DISEASE PROTEIN 7 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008122.1|UniProtKB=W5MNA6 W5MNA6 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of nuclear division#GO:0051783;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015831.1|UniProtKB=W5NFS9 W5NFS9 PTHR10741:SF5 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN-ASSOCIATED PROTEIN X nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012642.1|UniProtKB=W5N4K8 W5N4K8 EGFLAM PTHR15036:SF88 PIKACHURIN-LIKE PROTEIN PIKACHURIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014546.1|UniProtKB=W5NBA9 W5NBA9 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006437.1|UniProtKB=W5MHB5 W5MHB5 PTHR14402:SF20 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein insertion into membrane#GO:0051205 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001996.1|UniProtKB=W5M1P7 W5M1P7 PTHR24366:SF54 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY MEMBER 10 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000009848.1|UniProtKB=W5MUH9 W5MUH9 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004925.1|UniProtKB=W5MC17 W5MC17 PTHR43313:SF12 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 5 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;NAD-retinol dehydrogenase activity#GO:0004745;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007673.1|UniProtKB=W5MLQ9 W5MLQ9 PTHR45678:SF7 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER SLC25A12, MITOCHONDRIAL L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;acidic amino acid transmembrane transporter activity#GO:0015172 cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;respiratory electron transport chain#GO:0022904;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004629.1|UniProtKB=W5MAZ6 W5MAZ6 MCMDC2 PTHR11630:SF75 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;mitotic DNA replication initiation#GO:1902975;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012795.1|UniProtKB=W5N541 W5N541 PTHR12505:SF22 PHD FINGER TRANSCRIPTION FACTOR BAH AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007539.1|UniProtKB=W5ML88 W5ML88 PTHR45984:SF2 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM34 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;establishment of protein localization to mitochondrion#GO:0072655;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012441.1|UniProtKB=W5N3W0 W5N3W0 PTHR15938:SF0 TBP-1 INTERACTING PROTEIN HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG nucleic acid binding#GO:0003676;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 cellular aromatic compound metabolic process#GO:0006725;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 LEPOC|Ensembl=ENSLOCG00000017621.1|UniProtKB=W5NM67 W5NM67 PTHR18884:SF128 SEPTIN SI:CH211-282J17.12-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015649.1|UniProtKB=W5NF55 W5NF55 PTHR10127:SF870 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017336.1|UniProtKB=W5NLD2 W5NLD2 PTHR21461:SF45 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012135.1|UniProtKB=W5N2R9 W5N2R9 PTHR11849:SF181 ETS ETS TRANSLOCATION VARIANT 4 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001957.1|UniProtKB=W5M1L6 W5M1L6 PTHR24083:SF41 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010579.1|UniProtKB=W5MX52 W5MX52 PTHR15975:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000009932.1|UniProtKB=W5MUT3 W5MUT3 PTHR23341:SF1 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMG-I_HMG-Y molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000011175.1|UniProtKB=W5MZC1 W5MZC1 TMPRSS6 PTHR24253:SF62 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 6 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015908.1|UniProtKB=W5NG29 W5NG29 PTHR10574:SF279 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA 4 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000014345.1|UniProtKB=W5NAK7 W5NAK7 PTHR10869:SF246 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT TRANSMEMBRANE PROLYL 4-HYDROXYLASE protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014808.1|UniProtKB=W5NC74 W5NC74 PTHR13800:SF13 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014456.1|UniProtKB=W5NAY1 W5NAY1 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000014511.1|UniProtKB=W5NB50 W5NB50 PTHR45995:SF1 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 4 LEPOC|Ensembl=ENSLOCG00000011171.1|UniProtKB=W5MZB8 W5MZB8 PTHR45752:SF4 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 59 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005857.1|UniProtKB=W5MFB2 W5MFB2 PTHR18853:SF9 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 27 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000014257.1|UniProtKB=W5NA94 W5NA94 PTHR22972:SF5 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PEAK1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016368.1|UniProtKB=W5NHV0 W5NHV0 PTHR11574:SF0 KIT LIGAND KIT LIGAND molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 biological regulation#GO:0065007;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011235.1|UniProtKB=W5MZJ1 W5MZJ1 PTHR46595:SF2 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011573.1|UniProtKB=W5N0R8 W5N0R8 PTHR22599:SF63 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1B protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000009009.1|UniProtKB=W5MRH0 W5MRH0 PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE AND EMI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000008567.1|UniProtKB=W5MPW4 W5MPW4 PTHR11461:SF363 SERINE PROTEASE INHIBITOR, SERPIN SERINE (OR CYSTEINE) PROTEINASE INHIBITOR, CLADE A (ALPHA-1 ANTIPROTEINASE, ANTITRYPSIN), MEMBER 1, LIKE PRECURSOR-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000016199.1|UniProtKB=W5NH60 W5NH60 PLEKHG1 PTHR45924:SF1 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 LEPOC|Ensembl=ENSLOCG00000005013.1|UniProtKB=W5MCE6 W5MCE6 PTHR12845:SF3 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 16 positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008625.1|UniProtKB=W5MQ27 W5MQ27 PTHR11818:SF19 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A4 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009630.1|UniProtKB=W5MTR7 W5MTR7 PTHR23105:SF54 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000010208.1|UniProtKB=W5MVU3 W5MVU3 WDR12 PTHR19855:SF11 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 LEPOC|Ensembl=ENSLOCG00000015000.1|UniProtKB=W5NCW0 W5NCW0 PTHR11071:SF477 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013345.1|UniProtKB=W5N735 W5N735 PTHR46270:SF2 ARMADILLO-TYPE FOLD-RELATED TIR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006777.1|UniProtKB=W5MIH7 W5MIH7 PTHR10671:SF35 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003300.1|UniProtKB=W5M688 W5M688 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 inorganic molecular entity transmembrane transporter activity#GO:0015318;carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;inorganic anion transmembrane transporter activity#GO:0015103;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;inorganic anion transport#GO:0015698 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017530.1|UniProtKB=W5NLX6 W5NLX6 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011636.1|UniProtKB=W5N0Z8 W5N0Z8 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML38 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000004052.1|UniProtKB=W5M8Y2 W5M8Y2 PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016976.1|UniProtKB=W5NK24 W5NK24 HS3ST5 PTHR10605:SF46 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 5 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011941.1|UniProtKB=W5N226 W5N226 PTHR11375:SF2 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER B protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006316.1|UniProtKB=W5MGY1 W5MGY1 PTHR45874:SF2 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-C10 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016275.1|UniProtKB=W5NHG7 W5NHG7 OSBPL8 PTHR10972:SF216 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 8 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;cortical endoplasmic reticulum#GO:0032541 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000010183.1|UniProtKB=W5MVR9 W5MVR9 CMPK1 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924;De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153 LEPOC|Ensembl=ENSLOCG00000004763.1|UniProtKB=W5MBF5 W5MBF5 PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;pentosyltransferase activity#GO:0016763 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 LEPOC|Ensembl=ENSLOCG00000006956.1|UniProtKB=W5MJ60 W5MJ60 PTHR46568:SF1 ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL LEPOC|Ensembl=ENSLOCG00000002897.1|UniProtKB=W5M4U5 W5M4U5 PTHR24083:SF44 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006172.1|UniProtKB=W5MGE5 W5MGE5 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014962.1|UniProtKB=W5NCR4 W5NCR4 PTHR10502:SF28 ANNEXIN ANNEXIN A4 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013988.1|UniProtKB=W5N9D3 W5N9D3 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015067.1|UniProtKB=W5ND38 W5ND38 PTHR10373:SF25 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;regulation of metabolic process#GO:0019222;Wnt signaling pathway#GO:0016055;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Cadherin signaling pathway#P00012>TCF/LEF#P00465 LEPOC|Ensembl=ENSLOCG00000012362.1|UniProtKB=W5N3K9 W5N3K9 PTHR23036:SF21 CYTOKINE RECEPTOR CILIARY NEUROTROPHIC FACTOR RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular response to organic substance#GO:0071310;positive regulation of cell population proliferation#GO:0008284;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017065.1|UniProtKB=W5NKC9 W5NKC9 PTHR12974:SF25 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5A adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000002431.1|UniProtKB=W5M398 W5M398 PTHR24230:SF1 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 54-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002046.1|UniProtKB=W5M1W6 W5M1W6 PTHR13832:SF233 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1F regulation of protein modification process#GO:0031399;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteolysis#GO:0045862;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of catalytic activity#GO:0043085;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016010.1|UniProtKB=W5NGG1 W5NGG1 PTHR22069:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN S18 RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016629.1|UniProtKB=W5NIT2 W5NIT2 PTHR16290:SF5 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1B RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000004056.1|UniProtKB=W5M8Y3 W5M8Y3 GATC PTHR15004:SF0 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000011486.1|UniProtKB=W5N0F7 W5N0F7 PTHR23235:SF25 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 Huntington disease#P00029>Sp1#P00803 LEPOC|Ensembl=ENSLOCG00000016859.1|UniProtKB=W5NJN4 W5NJN4 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cellular process#GO:0009987 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014499.1|UniProtKB=W5NB39 W5NB39 PTHR45983:SF4 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 18 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008449.1|UniProtKB=W5MPJ4 W5MPJ4 PTHR22050:SF1 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001498.1|UniProtKB=W5M013 W5M013 PTHR24356:SF140 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003193.1|UniProtKB=W5M5W5 W5M5W5 PTHR24341:SF4 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000017456.1|UniProtKB=W5NLQ2 W5NLQ2 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007096.1|UniProtKB=W5MJN3 W5MJN3 PTHR43391:SF1 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8-LIKE ISOFORM X1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003413.1|UniProtKB=W5M6N7 W5M6N7 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAP kinase activity#GO:0043405;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000004311.1|UniProtKB=W5M9W5 W5M9W5 PTHR19134:SF203 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;nitrogen compound metabolic process#GO:0006807;cell junction organization#GO:0034330;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000671.1|UniProtKB=W5LX82 W5LX82 PTHR47306:SF2 SI:CH211-178J18.4-RELATED CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001516.1|UniProtKB=W5M035 W5M035 PTHR18898:SF2 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000001502.1|UniProtKB=W5M012 W5M012 PTHR22917:SF1 HEMOPEXIN DOMAIN-CONTAINING PROTEIN PROTEOGLYCAN 4 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012800.1|UniProtKB=W5N543 W5N543 PTHR11987:SF50 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8F transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005838.1|UniProtKB=W5MF88 W5MF88 PTHR21041:SF6 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DC-STAMP DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000010488.1|UniProtKB=W5MWV3 W5MWV3 PTHR10177:SF193 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;organelle localization#GO:0051640;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;establishment of organelle localization#GO:0051656;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;mitotic metaphase chromosome alignment#GO:0007080;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;chromosome localization#GO:0050000;regulation of phosphorylation#GO:0042325;metaphase chromosome alignment#GO:0051310;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Cell cycle#P00013>Cyclin B#P00486;p53 pathway#P00059>Cyclin B#P04614 LEPOC|Ensembl=ENSLOCG00000016584.1|UniProtKB=W5NIM7 W5NIM7 PTHR45715:SF3 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890 LEPOC|Ensembl=ENSLOCG00000015664.1|UniProtKB=W5NF72 W5NF72 PTHR21096:SF0 PROTEIN FAM136A PROTEIN FAM136A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001993.1|UniProtKB=W5M1R0 W5M1R0 PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017751.1|UniProtKB=W5NMJ6 W5NMJ6 PTHR28613:SF7 SI:CH211-232M10.4-RELATED TRANSMEMBRANE PROTEIN 238 LEPOC|Ensembl=ENSLOCG00000000958.1|UniProtKB=W5LY64 W5LY64 PTHR11242:SF14 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9C chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017135.1|UniProtKB=W5NKL7 W5NKL7 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004681.1|UniProtKB=W5MB42 W5MB42 TMEM119 PTHR28645:SF1 TRANSMEMBRANE PROTEIN 119 TRANSMEMBRANE PROTEIN 119 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell population proliferation#GO:0008284;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;positive regulation of developmental process#GO:0051094;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016090.1|UniProtKB=W5NGR5 W5NGR5 PTHR10224:SF15 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL ES1 PROTEIN, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009138.1|UniProtKB=W5MRZ1 W5MRZ1 PTHR10151:SF21 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 2 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;exonuclease activity#GO:0004527;phosphoric ester hydrolase activity#GO:0042578;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;phosphoric diester hydrolase activity#GO:0008081;ion binding#GO:0043167;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006753.1|UniProtKB=W5MIF5 W5MIF5 PTHR24253:SF163 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE, SERINE 4A ISOFORM X1-RELATED serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000093.1|UniProtKB=W5LVF1 W5LVF1 PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;cyclase activity#GO:0009975;catalytic activity#GO:0003824 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003886.1|UniProtKB=W5M8D5 W5M8D5 PTHR46319:SF2 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 9 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 TGF-beta signaling pathway#P00052>SARA#P01281 LEPOC|Ensembl=ENSLOCG00000003503.1|UniProtKB=W5M6Y9 W5M6Y9 PTHR42748:SF7 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA LIKE REDOX SENSOR 1-RELATED LEPOC|Ensembl=ENSLOCG00000007646.1|UniProtKB=W5MLN1 W5MLN1 PDE2A PTHR11347:SF102 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;binding#GO:0005488;catalytic activity#GO:0003824;identical protein binding#GO:0042802;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 positive regulation of gene expression#GO:0010628;heterocycle catabolic process#GO:0046700;cyclic nucleotide metabolic process#GO:0009187;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;ribonucleotide catabolic process#GO:0009261;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of mitochondrion organization#GO:0010821;purine ribonucleotide catabolic process#GO:0009154;regulation of signal transduction#GO:0009966;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;organophosphate catabolic process#GO:0046434;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;phosphorus metabolic process#GO:0006793;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;purine nucleotide catabolic process#GO:0006195;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;organonitrogen compound metabolic process#GO:1901564;cGMP-mediated signaling#GO:0019934;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cyclic-nucleotide-mediated signaling#GO:0019935;nucleobase-containing small molecule metabolic process#GO:0055086 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;perinuclear region of cytoplasm#GO:0048471;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;plasma membrane region#GO:0098590;membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;nucleus#GO:0005634;cell junction#GO:0030054;intracellular organelle lumen#GO:0070013;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;plasma membrane#GO:0005886 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000014059.1|UniProtKB=W5N9M4 W5N9M4 PTHR13650:SF0 SPATACSIN SPATACSIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018273.1|UniProtKB=W5NP15 W5NP15 PTHR11984:SF29 CONNEXIN GAP JUNCTION BETA-5 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000014176.1|UniProtKB=W5NA02 W5NA02 H3-5 PTHR45810:SF13 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009395.1|UniProtKB=W5MSV1 W5MSV1 PTHR22602:SF0 TRANSFERASE CAF17, MITOCHONDRIAL-RELATED TRANSFERASE CAF17, MITOCHONDRIAL-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000011810.1|UniProtKB=W5N1L6 W5N1L6 UTS2R PTHR24230:SF60 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005263.1|UniProtKB=W5MD94 W5MD94 PTHR24271:SF81 KALLIKREIN-RELATED GRANZYME B serine protease#PC00203;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Granzyme B#P00265 LEPOC|Ensembl=ENSLOCG00000002235.1|UniProtKB=W5M2K0 W5M2K0 PTHR10133:SF27 DNA POLYMERASE I DNA POLYMERASE NU DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016676.1|UniProtKB=W5NIZ6 W5NIZ6 PTHR45627:SF15 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000004751.1|UniProtKB=W5MBD9 W5MBD9 ARPP21 PTHR15672:SF14 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN CAMP-REGULATED PHOSPHOPROTEIN 21 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011323.1|UniProtKB=W5MZV2 W5MZV2 PTHR35077:SF2 SIMILAR TO AI661453 PROTEIN SIMILAR TO AI661453 PROTEIN LEPOC|Ensembl=ENSLOCG00000007727.1|UniProtKB=W5MLZ2 W5MLZ2 ELOVL7 PTHR11157:SF118 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000005044.1|UniProtKB=W5MCG6 W5MCG6 PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cell cycle phase transition#GO:1901987;positive regulation of mitotic nuclear division#GO:0045840;organonitrogen compound metabolic process#GO:1901564;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000007061.1|UniProtKB=W5MJK6 W5MJK6 PTHR11139:SF71 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE SMG1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008063.1|UniProtKB=W5MN27 W5MN27 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005508.1|UniProtKB=W5ME36 W5ME36 PTHR11920:SF497 GUANYLYL CYCLASE GUANYLATE CYCLASE adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000004059.1|UniProtKB=W5M8Z2 W5M8Z2 PTHR23291:SF32 BAX INHIBITOR-RELATED BAX INHIBITOR 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 Apoptosis signaling pathway#P00006>Bi1#P00277 LEPOC|Ensembl=ENSLOCG00000005985.1|UniProtKB=W5MFS7 W5MFS7 PTHR16040:SF8 AUSTRALIN, ISOFORM A-RELATED BOREALIN nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;spindle midzone#GO:0051233;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005568.1|UniProtKB=W5MEB7 W5MEB7 PTHR23288:SF9 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011580.1|UniProtKB=W5N0R4 W5N0R4 PTHR11767:SF99 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014769.1|UniProtKB=W5NC34 W5NC34 PTHR22957:SF320 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8B nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003651.1|UniProtKB=W5M7H7 W5M7H7 PTHR22984:SF11 SERINE/THREONINE-PROTEIN KINASE PIM AURORA KINASE-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011923.1|UniProtKB=W5N209 W5N209 PTHR14167:SF50 SH3 DOMAIN-CONTAINING ENDOPHILIN-A1 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;protein-containing complex disassembly#GO:0032984;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001663.1|UniProtKB=W5M0L1 W5M0L1 PTHR24083:SF168 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012619.1|UniProtKB=W5N4I0 W5N4I0 PTHR23074:SF72 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4B pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;vacuole organization#GO:0007033;cellular localization#GO:0051641;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000013568.1|UniProtKB=W5N7Y2 W5N7Y2 PTHR45975:SF2 NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000011781.1|UniProtKB=W5N1H9 W5N1H9 PTHR11346:SF179 GALECTIN GALECTIN extracellular matrix binding#GO:0050840;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;carbohydrate binding#GO:0030246;binding#GO:0005488;oligosaccharide binding#GO:0070492 negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of vesicle-mediated transport#GO:0060627;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;regulation of transport#GO:0051049;neutrophil chemotaxis#GO:0030593;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;myeloid leukocyte migration#GO:0097529;regulation of monoatomic ion transport#GO:0043269;negative regulation of cellular component organization#GO:0051129;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;macrophage chemotaxis#GO:0048246;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;neutrophil migration#GO:1990266;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of calcium ion transport#GO:0051924;positive regulation of transport#GO:0051050;negative regulation of transport#GO:0051051;cell motility#GO:0048870;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cell chemotaxis#GO:0060326;regulation of response to stimulus#GO:0048583;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;positive chemotaxis#GO:0050918;negative regulation of endocytosis#GO:0045806;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;external encapsulating structure#GO:0030312;membrane-bounded organelle#GO:0043227;collagen-containing extracellular matrix#GO:0062023;plasma membrane#GO:0005886 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000005288.1|UniProtKB=W5MDB3 W5MDB3 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;establishment of protein localization#GO:0045184;inner mitochondrial membrane organization#GO:0007007;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;mitochondrial membrane organization#GO:0007006;protein insertion into membrane#GO:0051205 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010428.1|UniProtKB=W5MWP0 W5MWP0 PTHR19134:SF468 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016862.1|UniProtKB=W5NJN8 W5NJN8 IQSEC3 PTHR10663:SF318 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004094.1|UniProtKB=W5M932 W5M932 PTHR43270:SF1 BETA-ALA-HIS DIPEPTIDASE BETA-ALA-HIS DIPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016308.1|UniProtKB=W5NHL9 W5NHL9 PTHR43347:SF3 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL ligase#PC00142 Methylcitrate cycle#P02754>Acetyl-CoA synthetase#P03030;Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 LEPOC|Ensembl=ENSLOCG00000005544.1|UniProtKB=W5ME88 W5ME88 PTHR10972:SF153 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000006102.1|UniProtKB=W5MG67 W5MG67 PTHR24089:SF762 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A25 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000050.1|UniProtKB=W5LVA3 W5LVA3 PTHR23238:SF5 RNA BINDING PROTEIN RNA-BINDING PROTEIN FUS molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010168.1|UniProtKB=W5MVP4 W5MVP4 PTHR19370:SF74 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 1 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001168.1|UniProtKB=W5LYV5 W5LYV5 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002473.1|UniProtKB=W5M3E4 W5M3E4 PTHR12943:SF5 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 2 PROTEIN response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000012211.1|UniProtKB=W5N320 W5N320 PTHR10373:SF32 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;regulation of metabolic process#GO:0019222;Wnt signaling pathway#GO:0016055;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 Angiogenesis#P00005>TCF#P00242;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Cadherin signaling pathway#P00012>TCF/LEF#P00465 LEPOC|Ensembl=ENSLOCG00000003581.1|UniProtKB=W5M788 W5M788 PTHR46115:SF8 THIOREDOXIN-LIKE PROTEIN 1 THIOREDOXIN-LIKE PROTEIN 1 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015481.1|UniProtKB=W5NEJ5 W5NEJ5 PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Huntington disease#P00029>TBP#P00779;General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 LEPOC|Ensembl=ENSLOCG00000004962.1|UniProtKB=W5MC70 W5MC70 PTHR11315:SF20 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE GAMMA-GLUTAMYL HYDROLASE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015217.1|UniProtKB=W5NDM0 W5NDM0 PTHR11480:SF3 SAPOSIN-RELATED BCDNA.GH08312 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015514.1|UniProtKB=W5NEN6 W5NEN6 PTHR10909:SF352 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-LIKE PROTEIN nucleotide binding#GO:0000166;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014401.1|UniProtKB=W5NAS8 W5NAS8 PTHR10841:SF24 SYNAPSIN SYNAPSIN-1 neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;signal release#GO:0023061;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;export from cell#GO:0140352;secretion by cell#GO:0032940 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 LEPOC|Ensembl=ENSLOCG00000011352.1|UniProtKB=W5MZZ6 W5MZZ6 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 LEPOC|Ensembl=ENSLOCG00000000806.1|UniProtKB=W5LXP0 W5LXP0 PTHR11506:SF30 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000004238.1|UniProtKB=W5M9M6 W5M9M6 PTHR24083:SF174 NUCLEAR HORMONE RECEPTOR HEPATIC NUCLEAR FACTOR 4BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003511.1|UniProtKB=W5M6Z5 W5M6Z5 CASTOR1 PTHR31131:SF3 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 1 cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000007006.1|UniProtKB=W5MJB6 W5MJB6 PTHR31021:SF3 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1-LIKE LEPOC|Ensembl=ENSLOCG00000012250.1|UniProtKB=W5N366 W5N366 PTHR11202:SF18 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016775.1|UniProtKB=W5NJC4 W5NJC4 PTHR33967:SF1 RAGULATOR COMPLEX PROTEIN LAMTOR4 RAGULATOR COMPLEX PROTEIN LAMTOR4 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045 LEPOC|Ensembl=ENSLOCG00000007684.1|UniProtKB=W5MLS2 W5MLS2 PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phosphatidylcholine biosynthetic process#GO:0006656;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003476.1|UniProtKB=W5M6V8 W5M6V8 PTHR24114:SF37 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74B LEPOC|Ensembl=ENSLOCG00000013330.1|UniProtKB=W5N721 W5N721 PTHR20932:SF4 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 2-RELATED LEPOC|Ensembl=ENSLOCG00000016441.1|UniProtKB=W5NI47 W5NI47 TAFA2 PTHR31770:SF1 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000006480.1|UniProtKB=W5MHG5 W5MHG5 PTHR12322:SF123 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX-AND MAB-3-RELATED TRANSCRIPTION FACTOR 2B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sex differentiation#GO:0007548;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011246.1|UniProtKB=W5MZM3 W5MZM3 PTHR11255:SF32 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004347.1|UniProtKB=W5M9Z8 W5M9Z8 PTHR22780:SF5 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007927.1|UniProtKB=W5MMN3 W5MMN3 PTHR10218:SF363 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN SUBUNIT ALPHA O1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Enkephalin release#P05913>G-Protein (i)#P05974;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Goalpha#P00729;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Opioid prodynorphin pathway#P05916>G-protein#P06002;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 LEPOC|Ensembl=ENSLOCG00000010329.1|UniProtKB=W5MWA0 W5MWA0 PTHR12957:SF23 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000012417.1|UniProtKB=W5N3T2 W5N3T2 PTHR10709:SF17 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014855.1|UniProtKB=W5NCD0 W5NCD0 PTHR34490:SF3 PROTEIN CBG12054-RELATED GALAXIN-LIKE ISOFORM X2 LEPOC|Ensembl=ENSLOCG00000015748.1|UniProtKB=W5NFH5 W5NFH5 PTHR24006:SF895 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002853.1|UniProtKB=W5M4Q1 W5M4Q1 PTHR46395:SF1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;regulation of vesicle-mediated transport#GO:0060627;regulation of small GTPase mediated signal transduction#GO:0051056 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>ASAP1#P00909 LEPOC|Ensembl=ENSLOCG00000016578.1|UniProtKB=W5NIL8 W5NIL8 PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;purine nucleoside catabolic process#GO:0006152;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;adenosine metabolic process#GO:0046085;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011008.1|UniProtKB=W5MYP4 W5MYP4 PTHR24327:SF26 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017250.1|UniProtKB=W5NL27 W5NL27 PTHR45716:SF3 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000014014.1|UniProtKB=W5N9G4 W5N9G4 PTHR11595:SF59 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER EF-HAND AND COILED-COIL DOMAIN-CONTAINING 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005612.1|UniProtKB=W5MEI0 W5MEI0 PTHR14002:SF10 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009376.1|UniProtKB=W5MSS5 W5MSS5 PTHR32247:SF4 DIABLO HOMOLOG, MITOCHONDRIAL DIRECT IAP-BINDING PROTEIN WITH LOW PI positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;neuron apoptotic process#GO:0051402;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;intrinsic apoptotic signaling pathway#GO:0097193;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017655.1|UniProtKB=W5NMA1 W5NMA1 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007929.1|UniProtKB=W5MMN2 W5MMN2 PTHR12411:SF1022 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN S, B.1-RELATED cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016334.1|UniProtKB=W5NHQ9 W5NHQ9 PTHR11616:SF101 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 leucine transport#GO:0015820;neutral amino acid transport#GO:0015804;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000011543.1|UniProtKB=W5N0M2 W5N0M2 PTHR13291:SF1 JOSEPHIN 1, 2 JOSEPHIN-1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011327.1|UniProtKB=W5MZV5 W5MZV5 PTHR19282:SF203 TETRASPANIN TETRASPANIN-13 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005690.1|UniProtKB=W5MER0 W5MER0 PTHR12763:SF7 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 15 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000004887.1|UniProtKB=W5MBW4 W5MBW4 SNAI3 PTHR24388:SF42 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013227.1|UniProtKB=W5N6N3 W5N6N3 PTHR35826:SF5 PROTEIN ATP6V1FNB-LIKE GENE 45521-RELATED LEPOC|Ensembl=ENSLOCG00000003557.1|UniProtKB=W5M747 W5M747 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003195.1|UniProtKB=W5M5W6 W5M5W6 PTHR44086:SF14 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED RHODANESE DOMAIN-CONTAINING PROTEIN thiosulfate sulfurtransferase activity#GO:0004792;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015448.1|UniProtKB=W5NEF5 W5NEF5 PTHR11461:SF13 SERINE PROTEASE INHIBITOR, SERPIN ANGIOTENSINOGEN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AngII#P05935 LEPOC|Ensembl=ENSLOCG00000003820.1|UniProtKB=W5M848 W5M848 PTHR11486:SF151 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000013325.1|UniProtKB=W5N722 W5N722 PTHR12894:SF49 CNH DOMAIN CONTAINING VAM6_VPS39-LIKE PROTEIN vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagy#GO:0006914;organelle fusion#GO:0048284;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011138.1|UniProtKB=W5MZ71 W5MZ71 PTHR11364:SF27 THIOSULFATE SULFERTANSFERASE SULFURTRANSFERASE thiosulfate sulfurtransferase activity#GO:0004792;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001298.1|UniProtKB=W5LZB4 W5LZB4 PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003160.1|UniProtKB=W5M5S2 W5M5S2 PTHR31180:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;axonemal microtubule#GO:0005879 LEPOC|Ensembl=ENSLOCG00000009167.1|UniProtKB=W5MS20 W5MS20 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;SNARE complex#GO:0031201;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013308.1|UniProtKB=W5N6Z9 W5N6Z9 PTHR10694:SF104 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4C histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000001149.1|UniProtKB=W5LYV1 W5LYV1 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003397.1|UniProtKB=W5M6L2 W5M6L2 PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067 LEPOC|Ensembl=ENSLOCG00000001657.1|UniProtKB=W5M0K3 W5M0K3 PTHR24160:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of organelle organization#GO:0010638;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of cytokinesis#GO:0032465;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;establishment of chromosome localization#GO:0051303;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic metaphase chromosome alignment#GO:0007080;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310 intracellular non-membrane-bounded organelle#GO:0043232;spindle pole#GO:0000922;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017824.1|UniProtKB=W5NMR8 W5NMR8 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000011223.1|UniProtKB=W5MZI5 W5MZI5 PTHR13160:SF4 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;oligosaccharyltransferase complex#GO:0008250;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011074.1|UniProtKB=W5MYY7 W5MYY7 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015336.1|UniProtKB=W5NE10 W5NE10 PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000384.1|UniProtKB=W5LWB2 W5LWB2 PTHR48051:SF2 FAMILY NOT NAMED LEUCINE RICH REPEAT CONTAINING 39 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018160.1|UniProtKB=W5NNQ2 W5NNQ2 BASP1 PTHR23212:SF0 BRAIN ACID SOLUBLE PROTEIN 1 BRAIN ACID SOLUBLE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012837.1|UniProtKB=W5N590 W5N590 PTHR48484:SF2 PRO-INTERLEUKIN-16 PRO-INTERLEUKIN-16 Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000017491.1|UniProtKB=W5NLT7 W5NLT7 POU3F4 PTHR11636:SF83 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012777.1|UniProtKB=W5N516 W5N516 PTHR15715:SF18 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA PROTEIN B scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012794.1|UniProtKB=W5N540 W5N540 PTHR18945:SF866 NEUROTRANSMITTER GATED ION CHANNEL ALPHA8 SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000009253.1|UniProtKB=W5MSD6 W5MSD6 PTHR45622:SF11 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013855.1|UniProtKB=W5N8Y1 W5N8Y1 PTHR22957:SF547 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 16 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003452.1|UniProtKB=W5M6U1 W5M6U1 PTHR24253:SF153 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE HEPSIN serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001806.1|UniProtKB=W5M137 W5M137 PTHR46886:SF1 INSULIN-LIKE GROWTH FACTOR II INSULIN-LIKE GROWTH FACTOR II intercellular signal molecule#PC00207;growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 LEPOC|Ensembl=ENSLOCG00000015659.1|UniProtKB=W5NF67 W5NF67 PTHR13288:SF8 SPLICING FACTOR 45 SPF45 SPLICING FACTOR 45 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004718.1|UniProtKB=W5MB97 W5MB97 PTHR24240:SF151 OPSIN NOVOPSIN-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002877.1|UniProtKB=W5M4S7 W5M4S7 PTHR10942:SF0 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003679.1|UniProtKB=W5M7M0 W5M7M0 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007826.1|UniProtKB=W5MM93 W5MM93 PTHR13693:SF50 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, NON-SPECIFIC, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;developmental process#GO:0032502;porphyrin-containing compound metabolic process#GO:0006778;biosynthetic process#GO:0009058;heme biosynthetic process#GO:0006783;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;pigment biosynthetic process#GO:0046148;protein metabolic process#GO:0019538;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;erythrocyte differentiation#GO:0030218;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cell development#GO:0048468;immune system process#GO:0002376;anatomical structure development#GO:0048856;multicellular organismal-level homeostasis#GO:0048871;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008858.1|UniProtKB=W5MQX1 W5MQX1 PTHR24403:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 827 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005374.1|UniProtKB=W5MDL8 W5MDL8 PTHR45822:SF8 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to fatty acid#GO:0070542;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to fatty acid#GO:0071398;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010574.1|UniProtKB=W5MX53 W5MX53 PTHR47157:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000003463.1|UniProtKB=W5M6V2 W5M6V2 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016940.1|UniProtKB=W5NJY0 W5NJY0 PTHR12316:SF24 NINJURIN-RELATED NINJURIN-2 cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006947.1|UniProtKB=W5MJ46 W5MJ46 PTHR24064:SF460 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010261.1|UniProtKB=W5MW04 W5MW04 PTHR11360:SF24 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 1 secondary active monocarboxylate transmembrane transporter activity#GO:0015355;solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007724.1|UniProtKB=W5MLW7 W5MLW7 PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83A-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000004048.1|UniProtKB=W5M8X4 W5M8X4 PTHR23115:SF228 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004737.1|UniProtKB=W5MBC3 W5MBC3 PTHR10110:SF191 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 8 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002743.1|UniProtKB=W5M4C0 W5M4C0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000016523.1|UniProtKB=W5NIE8 W5NIE8 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000141.1|UniProtKB=W5LVJ8 W5LVJ8 PTHR11977:SF27 VILLIN SCINDERIN LIKE A-RELATED cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;cellular component biogenesis#GO:0044085;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;central nervous system development#GO:0007417;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;cell projection assembly#GO:0030031;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000014046.1|UniProtKB=W5N9K4 W5N9K4 PTHR12027:SF78 WNT RELATED PROTEIN WNT-7A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of JNK cascade#GO:0046330;regulation of JNK cascade#GO:0046328;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000015844.1|UniProtKB=W5NFU7 W5NFU7 PTHR21847:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000012153.1|UniProtKB=W5N2U4 W5N2U4 PTHR16160:SF11 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 LEPOC|Ensembl=ENSLOCG00000007974.1|UniProtKB=W5MMR9 W5MMR9 PTHR34753:SF1 TELOMERASE RNA COMPONENT INTERACTING RNASE TELOMERASE RNA COMPONENT INTERACTING RNASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016058.1|UniProtKB=W5NGM4 W5NGM4 GPATCH2 PTHR14195:SF4 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001901.1|UniProtKB=W5M1E4 W5M1E4 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG nucleic acid binding#GO:0003676;protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;chromatin remodeling#GO:0006338 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013650.1|UniProtKB=W5N871 W5N871 PTHR11987:SF29 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8F transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009490.1|UniProtKB=W5MT90 W5MT90 IMPG2 PTHR12199:SF4 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 2 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014662.1|UniProtKB=W5NBN6 W5NBN6 C19orf54 PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 ACTIN MATURATION PROTEASE LEPOC|Ensembl=ENSLOCG00000006396.1|UniProtKB=W5MH66 W5MH66 PTHR24409:SF330 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 521 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012057.1|UniProtKB=W5N2H8 W5N2H8 PTHR46318:SF2 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000000524.1|UniProtKB=W5LWR9 W5LWR9 PTHR10339:SF25 ADP-RIBOSYLTRANSFERASE SECRETED EXOENZYME S transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013257.1|UniProtKB=W5N6U3 W5N6U3 PTHR23220:SF73 INTEGRIN ALPHA INTEGRIN ALPHA-IIB cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;cell adhesion mediated by integrin#GO:0033627;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;cell-matrix adhesion#GO:0007160;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Blood coagulation#P00011>GP IIb#P00410;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000000137.1|UniProtKB=W5LVJ2 W5LVJ2 PTHR34072:SF52 ENZYMATIC POLYPROTEIN-RELATED RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000011788.1|UniProtKB=W5N1J0 W5N1J0 PTHR11177:SF405 CHITINASE CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014824.1|UniProtKB=W5NC95 W5NC95 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;pICln-Sm protein complex#GO:0034715;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006902.1|UniProtKB=W5MIY7 W5MIY7 PTHR11961:SF12 CYTOCHROME C CYTOCHROME C Apoptosis signaling pathway#P00006>Cytochrome C#P00322;ATP synthesis#P02721>Cyt C#P02798 LEPOC|Ensembl=ENSLOCG00000011759.1|UniProtKB=W5N1F0 W5N1F0 ELOVL6 PTHR11157:SF125 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000016470.1|UniProtKB=W5NI89 W5NI89 PTHR15922:SF2 NEUROBLASTOMA-AMPLIFIED SEQUENCE NBAS SUBUNIT OF NRZ TETHERING COMPLEX protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001169.1|UniProtKB=W5LYW0 W5LYW0 PTHR23282:SF150 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. SI:CH211-106H4.4 LEPOC|Ensembl=ENSLOCG00000012561.1|UniProtKB=W5N4B9 W5N4B9 PTHR24347:SF398 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT GAMMA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 LEPOC|Ensembl=ENSLOCG00000002304.1|UniProtKB=W5M2V4 W5M2V4 PTHR23255:SF55 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 heart development#GO:0007507;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 LEPOC|Ensembl=ENSLOCG00000010680.1|UniProtKB=W5MXH3 W5MXH3 PTHR12446:SF34 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015820.1|UniProtKB=W5NFR6 W5NFR6 PTHR10151:SF79 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008319.1|UniProtKB=W5MNZ9 W5MNZ9 ADAMTS19 PTHR13723:SF197 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 19 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007845.1|UniProtKB=W5MMB5 W5MMB5 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015824.1|UniProtKB=W5NFS2 W5NFS2 PTHR12613:SF2 ERO1-RELATED ERO1-LIKE PROTEIN BETA protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007850.1|UniProtKB=W5MMC2 W5MMC2 LRRC51 PTHR46545:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 LEPOC|Ensembl=ENSLOCG00000018111.1|UniProtKB=W5NNK3 W5NNK3 PTHR31046:SF2 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 LEPOC|Ensembl=ENSLOCG00000013299.1|UniProtKB=W5N6Y1 W5N6Y1 PTHR23192:SF85 OLFACTOMEDIN-RELATED GLIOMEDIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003164.1|UniProtKB=W5M5S9 W5M5S9 PTHR21382:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010547.1|UniProtKB=W5MX15 W5MX15 PTHR32343:SF71 SERINE/ARGININE-RICH SPLICING FACTOR SPLICING REGULATORY GLUTAMIC ACID AND LYSINE RICH PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012296.1|UniProtKB=W5N3C1 W5N3C1 PTHR11486:SF21 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 10 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to wounding#GO:0009611;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;wound healing#GO:0042060;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;chemotaxis#GO:0006935;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000002581.1|UniProtKB=W5M3S2 W5M3S2 PTHR24067:SF258 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000007088.1|UniProtKB=W5MJP5 W5MJP5 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014324.1|UniProtKB=W5NAI0 W5NAI0 PTHR22811:SF60 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 3 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000008227.1|UniProtKB=W5MNM7 W5MNM7 PTHR23311:SF5 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA LEPOC|Ensembl=ENSLOCG00000002058.1|UniProtKB=W5M1X9 W5M1X9 PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005124.1|UniProtKB=W5MCR2 W5MCR2 PTHR47992:SF150 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1D hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>WIP-1#P04650;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#G04708 LEPOC|Ensembl=ENSLOCG00000006697.1|UniProtKB=W5MI81 W5MI81 PTHR44340:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006815.1|UniProtKB=W5MIM9 W5MIM9 PTHR23295:SF3 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED NUCLEAR RECEPTOR COACTIVATOR 5 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006352.1|UniProtKB=W5MH06 W5MH06 PTHR22923:SF103 CEREBELLIN-RELATED CEREBELLIN 20-RELATED cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000313.1|UniProtKB=W5LW51 W5LW51 PTHR14905:SF18 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING 10, TANDEM DUPLICATE 1-RELATED LEPOC|Ensembl=ENSLOCG00000010519.1|UniProtKB=W5MWX9 W5MWX9 PTHR46820:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;heterochromatin organization#GO:0070828;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;protein metabolic process#GO:0019538;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004583.1|UniProtKB=W5MAT1 W5MAT1 PTHR43391:SF9 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004438.1|UniProtKB=W5MAC6 W5MAC6 PTHR24253:SF70 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 5 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000679.1|UniProtKB=W5LX94 W5LX94 PTHR48066:SF1 CARNOSINE SYNTHASE 1 CARNOSINE SYNTHASE 1 LEPOC|Ensembl=ENSLOCG00000014811.1|UniProtKB=W5NC81 W5NC81 PTHR47980:SF6 LD44762P RAS-RELATED PROTEIN RAB-8B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012980.1|UniProtKB=W5N5S8 W5N5S8 PTHR14096:SF59 APOLIPOPROTEIN L APOLIPOPROTEIN L, 1 ISOFORM X1 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000007543.1|UniProtKB=W5ML90 W5ML90 NBL1 PTHR15283:SF5 GREMLIN 1 NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;animal organ development#GO:0048513;developmental process#GO:0032502;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000017729.1|UniProtKB=W5NMH4 W5NMH4 PTHR24234:SF7 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 132-RELATED negative regulation of biological process#GO:0048519;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle phase transition#GO:0044772;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;negative regulation of cell cycle process#GO:0010948;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015212.1|UniProtKB=W5NDL0 W5NDL0 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611 LEPOC|Ensembl=ENSLOCG00000000256.1|UniProtKB=W5LVX4 W5LVX4 PTHR24300:SF326 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015146.1|UniProtKB=W5NDD9 W5NDD9 PTHR10766:SF176 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014726.1|UniProtKB=W5NBW9 W5NBW9 PTHR10740:SF15 TRANSFORMING GROWTH FACTOR ALPHA EGF-LIKE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of mitotic nuclear division#GO:0007088;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of organelle organization#GO:0010638;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of mitotic cell cycle#GO:0007346;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000005648.1|UniProtKB=W5MEN6 W5MEN6 PTHR10336:SF166 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000016585.1|UniProtKB=W5NIM5 W5NIM5 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 LEPOC|Ensembl=ENSLOCG00000005180.1|UniProtKB=W5MCZ4 W5MCZ4 PTHR24061:SF441 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003690.1|UniProtKB=W5M7M1 W5M7M1 PTHR24229:SF2 NEUROPEPTIDES RECEPTOR DELTA-TYPE OPIOID RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (i)#P05973;Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985 LEPOC|Ensembl=ENSLOCG00000003001.1|UniProtKB=W5M583 W5M583 MTMR4 PTHR10807:SF64 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;regulation of catabolic process#GO:0009894;phosphatidylinositol dephosphorylation#GO:0046856;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;regulation of cellular catabolic process#GO:0031329;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013130.1|UniProtKB=W5N6B4 W5N6B4 PTHR46091:SF2 BLR7054 PROTEIN AMINE OXIDASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017675.1|UniProtKB=W5NMC1 W5NMC1 PTHR24225:SF48 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005471.1|UniProtKB=W5ME15 W5ME15 DNAI3 PTHR12442:SF5 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 3 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004291.1|UniProtKB=W5M9R6 W5M9R6 PTHR16070:SF2 PROTEIN FAM222A-RELATED PROTEIN FAM222A LEPOC|Ensembl=ENSLOCG00000013792.1|UniProtKB=W5N8Q0 W5N8Q0 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010955.1|UniProtKB=W5MYH9 W5MYH9 PTHR11035:SF22 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 1 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005946.1|UniProtKB=W5MFM3 W5MFM3 PTHR24243:SF9 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011752.1|UniProtKB=W5N1F1 W5N1F1 PTHR43243:SF19 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER C-TERMINAL DOMAIN-CONTAINING PROTEIN L-lysine transmembrane transporter activity#GO:0015189;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014419.1|UniProtKB=W5NAU1 W5NAU1 PTHR45752:SF5 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 28 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007286.1|UniProtKB=W5MKB3 W5MKB3 PTHR15564:SF2 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of cell cycle#GO:0045786;developmental process#GO:0032502;multicellular organism development#GO:0007275;response to lipid#GO:0033993;negative regulation of mitotic cell cycle#GO:0045930;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;dendrite#GO:0030425;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006736.1|UniProtKB=W5MIC8 W5MIC8 PTHR11485:SF49 TRANSFERRIN OTOLITH MATRIX PROTEIN 1 localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000016725.1|UniProtKB=W5NJ55 W5NJ55 PTHR13943:SF79 HRAS-LIKE SUPPRESSOR - RELATED HYPOTHETICAL LOC794087 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000016549.1|UniProtKB=W5NII0 W5NII0 PTHR13850:SF1 PLEIOTROPHIN FAMILY MEMBER PLEIOTROPHIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000011861.1|UniProtKB=W5N1S8 W5N1S8 PANK3 PTHR12280:SF21 PANTOTHENATE KINASE PANTOTHENATE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000005466.1|UniProtKB=W5MDY1 W5MDY1 PTHR23507:SF2 ZGC:174356 PROTON-COUPLED FOLATE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012569.1|UniProtKB=W5N4B5 W5N4B5 PTHR34339:SF1 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 response to external biotic stimulus#GO:0043207;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;innate immune response#GO:0045087;catabolic process#GO:0009056;defense response#GO:0006952;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;immune response#GO:0006955;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;regulation of macroautophagy#GO:0016241;cellular component organization#GO:0016043;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organelle disassembly#GO:1903008;defense response to symbiont#GO:0140546;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;reticulophagy#GO:0061709;response to stress#GO:0006950;positive regulation of macroautophagy#GO:0016239;defense response to other organism#GO:0098542;organelle organization#GO:0006996;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;autophagosome assembly#GO:0000045;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000011633.1|UniProtKB=W5N0Y4 W5N0Y4 PTHR12879:SF21 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE_C4-MONOOXYGENASE DES2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;amide metabolic process#GO:0043603;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000012884.1|UniProtKB=W5N5F3 W5N5F3 PTHR24399:SF28 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 25 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015166.1|UniProtKB=W5NDF5 W5NDF5 DEPDC4 PTHR16206:SF10 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012217.1|UniProtKB=W5N316 W5N316 PTHR19321:SF6 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;spindle elongation#GO:0051231;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;spindle midzone#GO:0051233;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014471.1|UniProtKB=W5NB11 W5NB11 PTHR10807:SF69 MYOTUBULARIN-RELATED MYOTUBULARIN hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;organelle localization#GO:0051640;regulation of catabolic process#GO:0009894;regulation of cellular component organization#GO:0051128;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of organelle assembly#GO:1902115;mitochondrion organization#GO:0007005;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;regulation of macroautophagy#GO:0016241;cellular component organization#GO:0016043;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;negative regulation of catabolic process#GO:0009895;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013460.1|UniProtKB=W5N7J1 W5N7J1 PTHR46294:SF3 SEGMENTATION PROTEIN EVEN-SKIPPED EVEN-SKIPPED-LIKE1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003530.1|UniProtKB=W5M715 W5M715 PTHR16195:SF16 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 14 LEPOC|Ensembl=ENSLOCG00000005196.1|UniProtKB=W5MCZ6 W5MCZ6 PTHR21040:SF5 BCDNA.GH04120 BETA-N-ACETYLHEXOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000010454.1|UniProtKB=W5MWQ4 W5MWQ4 PTHR14239:SF3 DUDULIN-RELATED METALLOREDUCTASE STEAP1-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004549.1|UniProtKB=W5MAM8 W5MAM8 PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Huntington disease#P00029>Arp2/3 complex#P00811 LEPOC|Ensembl=ENSLOCG00000008908.1|UniProtKB=W5MR41 W5MR41 PTHR15151:SF24 PROTEIN EIGER A PROLIFERATION-INDUCING LIGAND-LIKE PROTEIN-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014952.1|UniProtKB=W5NCQ2 W5NCQ2 PTHR15746:SF22 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 1 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017622.1|UniProtKB=W5NM68 W5NM68 PTHR45598:SF1 PROTEIN CBG11839-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005474.1|UniProtKB=W5ME13 W5ME13 PTHR15688:SF1 KINETOCHORE-ASSOCIATED PROTEIN 1 KINETOCHORE-ASSOCIATED PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 negative regulation of sister chromatid segregation#GO:0033046;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;protein-DNA complex organization#GO:0071824;kinetochore organization#GO:0051383;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;protein-DNA complex assembly#GO:0065004;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;macromolecule localization#GO:0033036;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;protein localization to kinetochore#GO:0034501;negative regulation of organelle organization#GO:0010639;mitotic nuclear division#GO:0140014;protein localization to organelle#GO:0033365;mitotic sister chromatid segregation#GO:0000070;kinetochore assembly#GO:0051382;non-membrane-bounded organelle assembly#GO:0140694;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;localization#GO:0051179;organelle assembly#GO:0070925;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000011173.1|UniProtKB=W5MZB9 W5MZB9 PTHR42966:SF1 N-ACETYLNEURAMINATE SYNTHASE SIALIC ACID SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000008050.1|UniProtKB=W5MN22 W5MN22 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;U2-type spliceosomal complex#GO:0005684;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000014753.1|UniProtKB=W5NC04 W5NC04 PTHR11579:SF19 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000007087.1|UniProtKB=W5MJM3 W5MJM3 PTHR10612:SF34 APOLIPOPROTEIN D APOLIPOPROTEIN D apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002346.1|UniProtKB=W5M2Z7 W5M2Z7 PTHR12210:SF112 DULLARD PROTEIN PHOSPHATASE CTD (CARBOXY-TERMINAL DOMAIN, RNA POLYMERASE II, POLYPEPTIDE A) SMALL PHOSPHATASE-LIKE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001734.1|UniProtKB=W5M0X6 W5M0X6 PTHR11923:SF110 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SCAVENGER RECEPTOR CLASS B MEMBER 1 cargo receptor activity#GO:0038024 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013870.1|UniProtKB=W5N904 W5N904 PTHR43520:SF29 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation binding#GO:0043169;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017448.1|UniProtKB=W5NLP4 W5NLP4 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015517.1|UniProtKB=W5NEP0 W5NEP0 PTHR14113:SF6 PICCOLO/BASSOON PROTEIN PICCOLO structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to synapse#GO:0035418;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;cytoskeleton#GO:0005856;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000015555.1|UniProtKB=W5NEU1 W5NEU1 PTHR43381:SF20 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004953.1|UniProtKB=W5MC46 W5MC46 PTHR24058:SF121 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005914.1|UniProtKB=W5MFI5 W5MFI5 NAA16 PTHR22767:SF5 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 16, NATA AUXILIARY SUBUNIT macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000014448.1|UniProtKB=W5NAY7 W5NAY7 PTHR22950:SF74 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 5 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;glycine transmembrane transporter activity#GO:0015187;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;glycine transport#GO:0015816 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008299.1|UniProtKB=W5MNX0 W5MNX0 CFAP418 PTHR33958:SF1 PROTEIN C8ORF37 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004366.1|UniProtKB=W5MA05 W5MA05 PTHR24068:SF129 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBE2F ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein neddylation#GO:0045116;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008168.1|UniProtKB=W5MNF3 W5MNF3 SLC16A14 PTHR11360:SF239 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 14 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000628.1|UniProtKB=W5LX70 W5LX70 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004073.1|UniProtKB=W5M906 W5M906 PTHR10927:SF1 RIBOSOME MATURATION PROTEIN SBDS RIBOSOME MATURATION PROTEIN SBDS RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007835.1|UniProtKB=W5MMA2 W5MMA2 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003383.1|UniProtKB=W5M6J5 W5M6J5 PTHR45632:SF12 LD33804P KELCH-LIKE PROTEIN 15 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;response to topologically incorrect protein#GO:0035966;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010474.1|UniProtKB=W5MWT1 W5MWT1 ADPRH PTHR16222:SF26 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH1 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016594.1|UniProtKB=W5NIQ4 W5NIQ4 PTHR46399:SF7 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 negative regulation of biological process#GO:0048519;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;regulation of sequestering of calcium ion#GO:0051282;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;release of sequestered calcium ion into cytosol#GO:0051209;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;striated muscle contraction#GO:0006941;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655;negative regulation of cellular process#GO:0048523;muscle system process#GO:0003012;muscle contraction#GO:0006936 bounding membrane of organelle#GO:0098588;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;sarcomere#GO:0030017;transmembrane transporter complex#GO:1902495;myofibril#GO:0030016;membrane protein complex#GO:0098796;sarcoplasmic reticulum#GO:0016529;Z disc#GO:0030018;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;contractile fiber#GO:0043292;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 LEPOC|Ensembl=ENSLOCG00000004222.1|UniProtKB=W5M9L1 W5M9L1 PTHR44874:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 34 TETRATRICOPEPTIDE REPEAT PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000004116.1|UniProtKB=W5M962 W5M962 PTHR15354:SF1 MUF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 41 LEPOC|Ensembl=ENSLOCG00000003754.1|UniProtKB=W5M7W6 W5M7W6 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012416.1|UniProtKB=W5N3T1 W5N3T1 PTHR12842:SF3 FI01459P PROTEIN FAM114A2 LEPOC|Ensembl=ENSLOCG00000007210.1|UniProtKB=W5MK17 W5MK17 PTHR10417:SF15 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING 11 LEPOC|Ensembl=ENSLOCG00000010643.1|UniProtKB=W5MXC9 W5MXC9 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 LEPOC|Ensembl=ENSLOCG00000012545.1|UniProtKB=W5N4D0 W5N4D0 RYR3 PTHR46399:SF9 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 negative regulation of biological process#GO:0048519;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;regulation of sequestering of calcium ion#GO:0051282;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;release of sequestered calcium ion into cytosol#GO:0051209;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;striated muscle contraction#GO:0006941;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655;negative regulation of cellular process#GO:0048523;muscle system process#GO:0003012;muscle contraction#GO:0006936 bounding membrane of organelle#GO:0098588;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;sarcomere#GO:0030017;transmembrane transporter complex#GO:1902495;myofibril#GO:0030016;membrane protein complex#GO:0098796;sarcoplasmic reticulum#GO:0016529;Z disc#GO:0030018;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;contractile fiber#GO:0043292;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 LEPOC|Ensembl=ENSLOCG00000012150.1|UniProtKB=W5N2T7 W5N2T7 PTHR24403:SF63 ZINC FINGER PROTEIN SI:DKEY-154P10.3 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010622.1|UniProtKB=W5MXB0 W5MXB0 PTHR13283:SF11 KREV INTERACTION TRAPPED 1-RELATED KREV INTERACTION TRAPPED PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of multicellular organismal development#GO:2000026;cellular homeostasis#GO:0019725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003181.1|UniProtKB=W5M5V3 W5M5V3 PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001383.1|UniProtKB=W5LZL6 W5LZL6 PTHR45976:SF4 ARMADILLO SEGMENT POLARITY PROTEIN CATENIN BETA-1 phosphatase binding#GO:0019902;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;cell adhesion molecule binding#GO:0050839;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;plasma membrane#GO:0005886 Cadherin signaling pathway#P00012>betacatenin#P00463;p53 pathway feedback loops 2#P04398>beta-catenin#P04670;Wnt signaling pathway#P00057>Beta-Catenin#P01432;Angiogenesis#P00005>beta catenin#P00187;Alzheimer disease-presenilin pathway#P00004>beta-catenin#P00156;CCKR signaling map#P06959>beta-catenin#P07150;Gonadotropin-releasing hormone receptor pathway#P06664>CTNNB1#P06838 LEPOC|Ensembl=ENSLOCG00000010801.1|UniProtKB=W5MXX8 W5MXX8 PTHR15302:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF103 E3 UBIQUITIN-PROTEIN LIGASE RNF103 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010777.1|UniProtKB=W5MXU2 W5MXU2 PTHR46263:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 7 ARMADILLO REPEAT-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000017778.1|UniProtKB=W5NMM3 W5NMM3 SLITRK1 PTHR45773:SF7 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 1 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of synapse assembly#GO:0051965;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011999.1|UniProtKB=W5N2A7 W5N2A7 PTHR22870:SF155 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005358.1|UniProtKB=W5MDJ5 W5MDJ5 PTHR23427:SF1 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011237.1|UniProtKB=W5MZJ5 W5MZJ5 PTHR11866:SF6 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cytosolic calcium ion concentration#GO:0007204;response to lipid#GO:0033993;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;defense response#GO:0006952;signaling#GO:0023052;response to organic substance#GO:0010033;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of response to stress#GO:0080134;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000010271.1|UniProtKB=W5MW18 W5MW18 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000009984.1|UniProtKB=W5MV05 W5MV05 PTHR24353:SF82 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA protein kinase A binding#GO:0051018;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099;Nicotine pharmacodynamics pathway#P06587>PRKACA#P06588;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Endothelin signaling pathway#P00019>PKA#P00570 LEPOC|Ensembl=ENSLOCG00000004355.1|UniProtKB=W5MA02 W5MA02 PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000000933.1|UniProtKB=W5LY36 W5LY36 TRIM50 PTHR24103:SF326 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM50 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013066.1|UniProtKB=W5N639 W5N639 PTHR23342:SF0 N-ACETYLGLUTAMATE SYNTHASE N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 Arginine biosynthesis#P02728>N-acetylglutamate synthase#P02848 LEPOC|Ensembl=ENSLOCG00000016129.1|UniProtKB=W5NGX3 W5NGX3 PTHR10241:SF22 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5 nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;myosin binding#GO:0017022;binding#GO:0005488;molecular function regulator activity#GO:0098772;syntaxin binding#GO:0019905;protein binding#GO:0005515;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;SNARE binding#GO:0000149 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;secretion by cell#GO:0032940 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017618.1|UniProtKB=W5NM64 W5NM64 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR ODORANT RECEPTOR-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012156.1|UniProtKB=W5N2U0 W5N2U0 PTHR24339:SF66 HOMEOBOX PROTEIN EMX-RELATED EMPTY SPIRACLES HOMEOBOX 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017098.1|UniProtKB=W5NKH0 W5NKH0 PTHR14401:SF6 CENTROMERE PROTEIN K CENTROMERE PROTEIN K nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 LEPOC|Ensembl=ENSLOCG00000005462.1|UniProtKB=W5MDZ1 W5MDZ1 PTHR22826:SF49 RHO GUANINE EXCHANGE FACTOR-RELATED KALIRIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;intracellular signal transduction#GO:0035556;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Huntington disease#P00029>Duo#P00773 LEPOC|Ensembl=ENSLOCG00000002017.1|UniProtKB=W5M1T8 W5M1T8 SUCNR1 PTHR24231:SF14 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SUCCINATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007567.1|UniProtKB=W5MLC2 W5MLC2 PTHR10619:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000017181.1|UniProtKB=W5NKS6 W5NKS6 PTHR46129:SF3 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-14-RELATED lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017350.1|UniProtKB=W5NLE6 W5NLE6 PTHR19290:SF96 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009154.1|UniProtKB=W5MS03 W5MS03 PTHR23239:SF358 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016066.1|UniProtKB=W5NGP1 W5NGP1 PTHR11933:SF5 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000006628.1|UniProtKB=W5MHZ5 W5MHZ5 PTHR22624:SF38 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4C cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;mitophagy#GO:0000423;protein modification process#GO:0036211;gene expression#GO:0010467;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010005.1|UniProtKB=W5MV32 W5MV32 PTHR22774:SF15 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3A LEPOC|Ensembl=ENSLOCG00000011310.1|UniProtKB=W5MZU0 W5MZU0 PTHR11346:SF97 GALECTIN GALECTIN-1 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;carbohydrate binding#GO:0030246;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002681.1|UniProtKB=W5M439 W5M439 PTHR24270:SF55 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VERY LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000002248.1|UniProtKB=W5M2L5 W5M2L5 PTHR24132:SF24 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013810.1|UniProtKB=W5N8S2 W5N8S2 PTHR13693:SF50 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, NON-SPECIFIC, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;developmental process#GO:0032502;porphyrin-containing compound metabolic process#GO:0006778;biosynthetic process#GO:0009058;heme biosynthetic process#GO:0006783;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;pigment biosynthetic process#GO:0046148;protein metabolic process#GO:0019538;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;erythrocyte differentiation#GO:0030218;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cell development#GO:0048468;immune system process#GO:0002376;anatomical structure development#GO:0048856;multicellular organismal-level homeostasis#GO:0048871;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015772.1|UniProtKB=W5NFK7 W5NFK7 PTHR15034:SF5 DEATH DOMAIN-CONTAINING PROTEIN CRADD DEATH DOMAIN-CONTAINING PROTEIN CRADD Wnt signaling pathway#P00057>Frizzled#P01428;Apoptosis signaling pathway#P00006>RAIDD#P00294;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000001610.1|UniProtKB=W5M0P5 W5M0P5 PTHR11412:SF150 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-RELATED protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000018183.1|UniProtKB=W5NNS5 W5NNS5 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000859.1|UniProtKB=W5LXU9 W5LXU9 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015753.1|UniProtKB=W5NFJ2 W5NFJ2 PTHR48012:SF17 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 LEPOC|Ensembl=ENSLOCG00000004829.1|UniProtKB=W5MBP3 W5MBP3 PTHR13624:SF4 RE42071P TRANSMEMBRANE PROTEIN 161A LEPOC|Ensembl=ENSLOCG00000017865.1|UniProtKB=W5NMV9 W5NMV9 PTHR31655:SF3 PROTEIN FAM78A PROTEIN FAM78A LEPOC|Ensembl=ENSLOCG00000007067.1|UniProtKB=W5MJJ9 W5MJJ9 PTHR11220:SF1 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006035.1|UniProtKB=W5MFY1 W5MFY1 PTHR14256:SF5 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 4-LIKE 2 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015637.1|UniProtKB=W5NF49 W5NF49 PTHR10183:SF322 CALPAIN CALPAIN-11 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000001962.1|UniProtKB=W5M1L1 W5M1L1 PTHR31253:SF0 BRI3-BINDING PROTEIN BRI3-BINDING PROTEIN LEPOC|Ensembl=ENSLOCG00000004527.1|UniProtKB=W5MAK5 W5MAK5 PTHR24234:SF6 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5 regulation of DNA-binding transcription factor activity#GO:0051090;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;behavior#GO:0007610;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018199.1|UniProtKB=W5NNU1 W5NNU1 KCTD21 PTHR14499:SF57 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD21 cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014030.1|UniProtKB=W5N9I9 W5N9I9 PTHR23023:SF266 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004999.1|UniProtKB=W5MCA9 W5MCA9 PTHR19300:SF34 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016509.1|UniProtKB=W5NID3 W5NID3 PTHR10052:SF1 60S RIBOSOMAL PROTEIN L18A LARGE RIBOSOMAL SUBUNIT PROTEIN EL20 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014767.1|UniProtKB=W5NC24 W5NC24 PTHR10306:SF10 SYNAPTOPHYSIN SYNAPTOPHYSIN synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptophysin#P05777 LEPOC|Ensembl=ENSLOCG00000014875.1|UniProtKB=W5NCG1 W5NCG1 PTHR21308:SF2 PHYTANOYL-COA ALPHA-HYDROXYLASE ALPHA-KETOGLUTARATE-DEPENDENT HYPOPHOSPHITE DIOXYGENASE-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000010958.1|UniProtKB=W5MYI8 W5MYI8 PTHR43323:SF2 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;terpenoid biosynthetic process#GO:0016114;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;terpenoid metabolic process#GO:0006721;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 LEPOC|Ensembl=ENSLOCG00000007180.1|UniProtKB=W5MJY0 W5MJY0 PTHR46962:SF1 SERINE/THREONINE-PROTEIN KINASE KIST SERINE_THREONINE-PROTEIN KINASE KIST transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoprotein complex binding#GO:0043021;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of localization#GO:0032879;peptidyl-amino acid modification#GO:0018193;regulation of translational initiation#GO:0006446;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of protein transport#GO:0051223;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular localization#GO:0060341;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of establishment of protein localization#GO:0070201;regulation of cellular metabolic process#GO:0031323 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;neuron projection#GO:0043005;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006347.1|UniProtKB=W5MH02 W5MH02 PTHR12113:SF11 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 1 signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000014305.1|UniProtKB=W5NAG8 W5NAG8 PTHR11255:SF33 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE KAPPA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009799.1|UniProtKB=W5MUC0 W5MUC0 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008127.1|UniProtKB=W5MNA4 W5MNA4 PTHR24250:SF54 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B2 PRECURSOR hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002103.1|UniProtKB=W5M228 W5M228 PTHR24231:SF47 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 82-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011065.1|UniProtKB=W5MYX6 W5MYX6 C1GALT1 PTHR23033:SF13 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1 galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001164.1|UniProtKB=W5LYV3 W5LYV3 PTHR15224:SF1 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007625.1|UniProtKB=W5MLJ2 W5MLJ2 PTHR12253:SF19 RH14732P GROUP 3 SECRETORY PHOSPHOLIPASE A2 LEPOC|Ensembl=ENSLOCG00000000759.1|UniProtKB=W5LXI7 W5LXI7 PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 LEPOC|Ensembl=ENSLOCG00000008472.1|UniProtKB=W5MPK8 W5MPK8 PTHR45752:SF80 LEUCINE-RICH REPEAT-CONTAINING LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010924.1|UniProtKB=W5MYE0 W5MYE0 PTHR24356:SF149 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;mitotic cell cycle process#GO:1903047;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;positive regulation of programmed cell death#GO:0043068;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;hippo signaling#GO:0035329;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209 intracellular non-membrane-bounded organelle#GO:0043232;spindle pole#GO:0000922;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015586.1|UniProtKB=W5NEY3 W5NEY3 PTHR23077:SF9 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX6 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004781.1|UniProtKB=W5MBK4 W5MBK4 PTHR24103:SF570 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM63 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005325.1|UniProtKB=W5MDF4 W5MDF4 BPNT2 PTHR43028:SF4 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL MONOPHOSPHATASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014276.1|UniProtKB=W5NAC1 W5NAC1 PTHR11346:SF32 GALECTIN GALECTIN-4 carbohydrate binding#GO:0030246;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008871.1|UniProtKB=W5MQZ3 W5MQZ3 PTHR24238:SF79 G-PROTEIN COUPLED RECEPTOR GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008645.1|UniProtKB=W5MQ71 W5MQ71 PTHR11480:SF3 SAPOSIN-RELATED BCDNA.GH08312 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013503.1|UniProtKB=W5N7P9 W5N7P9 PTHR23169:SF7 ENVOPLAKIN ENVOPLAKIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;wound healing#GO:0042060;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000000348.1|UniProtKB=W5LW72 W5LW72 PTHR47266:SF28 ENDONUCLEASE-RELATED TRANSPOSON TF2-1 POLYPROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000017442.1|UniProtKB=W5NLN8 W5NLN8 PTHR23411:SF41 TAPASIN IG KAPPA-B4 CHAIN C REGION immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013771.1|UniProtKB=W5N8M0 W5N8M0 PTHR20875:SF6 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017461.1|UniProtKB=W5NLQ7 W5NLQ7 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002798.1|UniProtKB=W5M4J2 W5M4J2 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017218.1|UniProtKB=W5NKY0 W5NKY0 PTHR43313:SF43 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008972.1|UniProtKB=W5MRB9 W5MRB9 GPANK1 PTHR20923:SF1 BAT4 PROTEIN-RELATED G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012643.1|UniProtKB=W5N4K3 W5N4K3 PTHR35346:SF1 BEN DOMAIN-CONTAINING PROTEIN 6 BEN DOMAIN-CONTAINING PROTEIN 6 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;positive regulation of cell differentiation#GO:0045597;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;negative regulation of Notch signaling pathway#GO:0045746;regulation of neuron differentiation#GO:0045664;regulation of Notch signaling pathway#GO:0008593;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016282.1|UniProtKB=W5NHH9 W5NHH9 TSHR PTHR24372:SF1 GLYCOPROTEIN HORMONE RECEPTOR LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of adenylate cyclase activity#GO:0045762;reproductive system development#GO:0061458;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;rhythmic process#GO:0048511;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;hormone-mediated signaling pathway#GO:0009755;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;reproductive process#GO:0022414;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;male sex differentiation#GO:0046661;response to organic substance#GO:0010033;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular response to organic substance#GO:0071310;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;developmental process involved in reproduction#GO:0003006;response to stimulus#GO:0050896;response to hormone#GO:0009725;reproduction#GO:0000003;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of lyase activity#GO:0051349 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011361.1|UniProtKB=W5N002 W5N002 PTHR38926:SF64 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002644.1|UniProtKB=W5M3Z6 W5M3Z6 PTHR10465:SF0 TRANSMEMBRANE GTPASE FZO1 SARCALUMENIN LEPOC|Ensembl=ENSLOCG00000016080.1|UniProtKB=W5NGQ5 W5NGQ5 PTHR13408:SF5 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000016453.1|UniProtKB=W5NI64 W5NI64 CHGB PTHR10583:SF4 CHROMOGRANIN SECRETOGRANIN-1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009841.1|UniProtKB=W5MUG8 W5MUG8 PTHR24206:SF95 OS06G0237300 PROTEIN CYTOSKELETON-ASSOCIATED LIM DOMAIN PROTEIN-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011259.1|UniProtKB=W5MZN4 W5MZN4 PTHR47827:SF5 AHD DOMAIN-CONTAINING PROTEIN PROTEIN AF-9 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008112.1|UniProtKB=W5MN97 W5MN97 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;organelle#GO:0043226;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015048.1|UniProtKB=W5ND22 W5ND22 PTHR12844:SF12 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002341.1|UniProtKB=W5M2Z1 W5M2Z1 PTHR12756:SF24 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002111.1|UniProtKB=W5M243 W5M243 PTHR24219:SF6 LIM DOMAIN-CONTAINING PROTEIN JUB WILMS TUMOR PROTEIN 1-INTERACTING PROTEIN molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to abiotic stimulus#GO:0009628;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;response to oxygen levels#GO:0070482;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;negative regulation of signaling#GO:0023057;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 supramolecular complex#GO:0099080;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008943.1|UniProtKB=W5MR87 W5MR87 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003341.1|UniProtKB=W5M6E3 W5M6E3 PTHR45836:SF2 SLIT HOMOLOG SLIT HOMOLOG 2 PROTEIN heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of cell growth#GO:0001558;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 LEPOC|Ensembl=ENSLOCG00000016200.1|UniProtKB=W5NH66 W5NH66 PTHR12352:SF21 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;extracellular matrix binding#GO:0050840;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604;extracellular region#GO:0005576;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003051.1|UniProtKB=W5M5D2 W5M5D2 ENY2 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;RNA localization#GO:0006403;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;RNA transport#GO:0050658;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;mRNA transport#GO:0051028;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;nuclear export#GO:0051168;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014475.1|UniProtKB=W5NB09 W5NB09 PTHR13117:SF5 ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED PROTEIN RFT1 HOMOLOG macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;organic substance transport#GO:0071702;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;lipid translocation#GO:0034204;biological regulation#GO:0065007;lipid localization#GO:0010876;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007582.1|UniProtKB=W5MLD9 W5MLD9 PTHR11537:SF61 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000012928.1|UniProtKB=W5N5K9 W5N5K9 PTHR14388:SF7 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011537.1|UniProtKB=W5N0P5 W5N0P5 PTHR24416:SF91 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;hormone binding#GO:0042562;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basal plasma membrane#GO:0009925;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466;Gonadotropin-releasing hormone receptor pathway#P06664>EGFR#P06843 LEPOC|Ensembl=ENSLOCG00000004010.1|UniProtKB=W5M8T0 W5M8T0 PTHR14657:SF2 IGF-LIKE FAMILY RECEPTOR 1 IGF-LIKE FAMILY RECEPTOR 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002776.1|UniProtKB=W5M4F4 W5M4F4 PTHR10423:SF3 INSULIN-LIKE 3 INSULIN-LIKE 3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000008607.1|UniProtKB=W5MQ04 W5MQ04 PTHR11504:SF0 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005500.1|UniProtKB=W5ME38 W5ME38 PTHR23236:SF2 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000013298.1|UniProtKB=W5N6X7 W5N6X7 PTHR24409:SF392 ZINC FINGER PROTEIN 142 BCL6 TRANSCRIPTION REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015670.1|UniProtKB=W5NF81 W5NF81 PTHR11931:SF8 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 2 mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 LEPOC|Ensembl=ENSLOCG00000016184.1|UniProtKB=W5NH39 W5NH39 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008471.1|UniProtKB=W5MPJ9 W5MPJ9 ANKRD61 PTHR24161:SF21 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 35 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014190.1|UniProtKB=W5NA18 W5NA18 PTHR24366:SF35 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND TRANSMEMBRANE DOMAINS 1 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000008043.1|UniProtKB=W5MN12 W5MN12 PTHR16008:SF4 F-BOX ONLY PROTEIN 4 F-BOX ONLY PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000002456.1|UniProtKB=W5M3D1 W5M3D1 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009822.1|UniProtKB=W5MUE2 W5MUE2 CD38 PTHR10912:SF8 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;positive regulation of immune system process#GO:0002684;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of immune system process#GO:0002682;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell activation#GO:0050867;regulation of lymphocyte activation#GO:0051249;positive regulation of biological process#GO:0048518;regulation of B cell proliferation#GO:0030888;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000013094.1|UniProtKB=W5N671 W5N671 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015439.1|UniProtKB=W5NEE2 W5NEE2 PTHR24229:SF7 NEUROPEPTIDES RECEPTOR MU-TYPE OPIOID RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (s)#P05975;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004 LEPOC|Ensembl=ENSLOCG00000009519.1|UniProtKB=W5MTC4 W5MTC4 PTHR12473:SF8 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED LEPOC|Ensembl=ENSLOCG00000000805.1|UniProtKB=W5LXQ5 W5LXQ5 PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000006691.1|UniProtKB=W5MI69 W5MI69 PTHR21029:SF5 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 9-BINDING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000005360.1|UniProtKB=W5MDK1 W5MDK1 PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008296.1|UniProtKB=W5MNW6 W5MNW6 MINAR2 PTHR31530:SF4 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1-LIKE transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014970.1|UniProtKB=W5NCS3 W5NCS3 PTHR11685:SF212 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010402.1|UniProtKB=W5MWJ5 W5MWJ5 PTHR23192:SF33 OLFACTOMEDIN-RELATED MYOCILIN regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;ossification#GO:0001503;regulation of cellular process#GO:0050794;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;osteoblast differentiation#GO:0001649;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004576.1|UniProtKB=W5MAR9 W5MAR9 PTHR45682:SF3 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013923.1|UniProtKB=W5N958 W5N958 PTHR47238:SF4 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000209.1|UniProtKB=W5LVS6 W5LVS6 PTHR43827:SF10 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE ZGC:110366 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013780.1|UniProtKB=W5N8P0 W5N8P0 PTHR22775:SF48 SORTING NEXIN SORTING NEXIN-25 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018332.1|UniProtKB=W5NP74 W5NP74 PTHR46473:SF14 GH08155P LEUCINE RICH REPEAT CONTAINING 3B monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;molecular function activator activity#GO:0140677;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;protein binding#GO:0005515;channel regulator activity#GO:0016247;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000018272.1|UniProtKB=W5NP14 W5NP14 PTHR28599:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 LEPOC|Ensembl=ENSLOCG00000011490.1|UniProtKB=W5N0G4 W5N0G4 PTHR21324:SF10 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 2 regulation of biological process#GO:0050789;tissue homeostasis#GO:0001894;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;retina homeostasis#GO:0001895;regulation of cellular catabolic process#GO:0031329;anatomical structure homeostasis#GO:0060249;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012930.1|UniProtKB=W5N5M1 W5N5M1 PTHR10589:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Parkinson disease#P00049>UCH-L1#P01210 LEPOC|Ensembl=ENSLOCG00000004958.1|UniProtKB=W5MC72 W5MC72 PTHR18952:SF134 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 15 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005708.1|UniProtKB=W5MES8 W5MES8 PTHR13293:SF9 AKIRIN-RELATED AKIRIN-1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;regulation of cell migration#GO:0030334;regulation of cellular component biogenesis#GO:0044087;positive regulation of biological process#GO:0048518;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;regulation of immune response#GO:0050776;tissue regeneration#GO:0042246;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;regulation of defense response#GO:0031347;positive regulation of defense response#GO:0031349;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of plasma membrane bounded cell projection assembly#GO:0120032;positive regulation of RNA biosynthetic process#GO:1902680;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;growth#GO:0040007;regulation of cell differentiation#GO:0045595;positive regulation of leukocyte migration#GO:0002687;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to external stimulus#GO:0032101;developmental growth#GO:0048589;regulation of cell population proliferation#GO:0042127;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of DNA-templated transcription#GO:0006355;regeneration#GO:0031099;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of cellular biosynthetic process#GO:0031326;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of leukocyte chemotaxis#GO:0002690;positive regulation of RNA metabolic process#GO:0051254;cell migration#GO:0016477;positive regulation of response to biotic stimulus#GO:0002833 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012522.1|UniProtKB=W5N470 W5N470 PTHR13803:SF6 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24D cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000007359.1|UniProtKB=W5MKL7 W5MKL7 CFAP46 PTHR15977:SF15 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 LEPOC|Ensembl=ENSLOCG00000015206.1|UniProtKB=W5NDK4 W5NDK4 PTHR48092:SF14 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 1 GROUP H MEMBER 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009503.1|UniProtKB=W5MTB4 W5MTB4 CRHR2 PTHR45620:SF19 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING FACTOR RECEPTOR 2 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 LEPOC|Ensembl=ENSLOCG00000003871.1|UniProtKB=W5M8A9 W5M8A9 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007207.1|UniProtKB=W5MK14 W5MK14 PTHR20275:SF29 NAD KINASE NAD(+) KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000005702.1|UniProtKB=W5MES2 W5MES2 MTRFR PTHR46203:SF1 PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65 MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE translation release factor#PC00225;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000008534.1|UniProtKB=W5MPR9 W5MPR9 PTHR35442:SF1 TRANSMEMBRANE PROTEIN 249 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT TMEM249 LEPOC|Ensembl=ENSLOCG00000010655.1|UniProtKB=W5MXF0 W5MXF0 PTHR24300:SF153 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2G1-LIKE-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010157.1|UniProtKB=W5MVN3 W5MVN3 SUCLG2 PTHR11815:SF10 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;acyl-CoA metabolic process#GO:0006637;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000574.1|UniProtKB=W5LWX8 W5LWX8 PTHR10779:SF3 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017887.1|UniProtKB=W5NMY1 W5NMY1 PTHR24249:SF415 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 1 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013441.1|UniProtKB=W5N7G3 W5N7G3 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000015567.1|UniProtKB=W5NEV7 W5NEV7 PTHR11566:SF50 DYNAMIN DYNAMIN-1-LIKE PROTEIN ISOFORM X1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;organelle fission#GO:0048285;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;import into cell#GO:0098657;peroxisome organization#GO:0007031;mitochondrial fission#GO:0000266 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002594.1|UniProtKB=W5M3T9 W5M3T9 PTHR45733:SF8 FORMIN-J FORMIN-J LEPOC|Ensembl=ENSLOCG00000008430.1|UniProtKB=W5MPF0 W5MPF0 PTHR45762:SF4 ZINC FINGER RNA-BINDING PROTEIN INTERLEUKIN ENHANCER-BINDING FACTOR 3 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010371.1|UniProtKB=W5MWG0 W5MWG0 PTHR43520:SF30 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation binding#GO:0043169;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004469.1|UniProtKB=W5MAD3 W5MAD3 PTHR21402:SF5 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE SPECIFIC FACTOR 1 LEPOC|Ensembl=ENSLOCG00000005579.1|UniProtKB=W5MED0 W5MED0 PTHR11532:SF73 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008616.1|UniProtKB=W5MQ15 W5MQ15 PTHR22752:SF10 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 161 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007542.1|UniProtKB=W5ML92 W5ML92 PTHR11947:SF14 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012253.1|UniProtKB=W5N368 W5N368 PTHR46860:SF1 CHROMOBOX PROTEIN HOMOLOG 2 CHROMOBOX PROTEIN HOMOLOG 2 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000000475.1|UniProtKB=W5LWL4 W5LWL4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004462.1|UniProtKB=W5MAC9 W5MAC9 PTHR45872:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoGEF#P00728;Axon guidance mediated by semaphorins#P00007>RhoGEF#P00333;Cytoskeletal regulation by Rho GTPase#P00016>Rho GEFs#P00518 LEPOC|Ensembl=ENSLOCG00000014527.1|UniProtKB=W5NB69 W5NB69 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014897.1|UniProtKB=W5NCI7 W5NCI7 PTHR12867:SF6 GLYCOSYL TRANSFERASE-RELATED N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008385.1|UniProtKB=W5MP86 W5MP86 PTHR18966:SF108 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015833.1|UniProtKB=W5NFT2 W5NFT2 PTHR14484:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71L LEPOC|Ensembl=ENSLOCG00000006798.1|UniProtKB=W5MIK4 W5MIK4 PTHR11954:SF6 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR isomerase activity#GO:0016853;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 decarboxylase#PC00089;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000015864.1|UniProtKB=W5NFX5 W5NFX5 PTHR11266:SF17 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PROTEIN MPV17 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003448.1|UniProtKB=W5M6T1 W5M6T1 PTHR34491:SF113 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED FIBRONECTIN TYPE III DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G14620) LEPOC|Ensembl=ENSLOCG00000009796.1|UniProtKB=W5MUC1 W5MUC1 PTHR11455:SF22 CRYPTOCHROME CRYPTOCHROME DASH nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deoxyribodipyrimidine photo-lyase activity#GO:0003904;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;photoreactive repair#GO:0000719;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009;DNA photolyase#PC00014 LEPOC|Ensembl=ENSLOCG00000012622.1|UniProtKB=W5N4H8 W5N4H8 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 LEPOC|Ensembl=ENSLOCG00000009348.1|UniProtKB=W5MSP7 W5MSP7 PTHR24339:SF26 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005948.1|UniProtKB=W5MFM6 W5MFM6 PTHR46574:SF1 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010340.1|UniProtKB=W5MWC3 W5MWC3 PTHR46189:SF3 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 2 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;positive regulation of cell differentiation#GO:0045597;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein modification process#GO:0031401;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005100.1|UniProtKB=W5MCN1 W5MCN1 PTHR11486:SF74 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 19 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000001328.1|UniProtKB=W5LZF3 W5LZF3 PTHR14187:SF39 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12B LEPOC|Ensembl=ENSLOCG00000010494.1|UniProtKB=W5MWV4 W5MWV4 PTHR10024:SF45 SYNAPTOTAGMIN SYNAPTOTAGMIN-6 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000001192.1|UniProtKB=W5LYZ7 W5LYZ7 PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000017298.1|UniProtKB=W5NL94 W5NL94 PTHR25465:SF5 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007768.1|UniProtKB=W5MM23 W5MM23 CDKN2D PTHR24126:SF53 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED CYCLIN-DEPENDENT KINASE 4 INHIBITOR D RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017574.1|UniProtKB=W5NM20 W5NM20 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008593.1|UniProtKB=W5MPZ3 W5MPZ3 PTHR13462:SF16 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000005312.1|UniProtKB=W5MDG1 W5MDG1 PTHR24271:SF81 KALLIKREIN-RELATED GRANZYME B serine protease#PC00203;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Granzyme B#P00265 LEPOC|Ensembl=ENSLOCG00000007771.1|UniProtKB=W5MM43 W5MM43 PTHR32073:SF6 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2A LEPOC|Ensembl=ENSLOCG00000002894.1|UniProtKB=W5M4U9 W5M4U9 PTHR13139:SF2 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;mRNA binding#GO:0003729;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;double-stranded RNA binding#GO:0003725 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 LEPOC|Ensembl=ENSLOCG00000005482.1|UniProtKB=W5ME22 W5ME22 PTHR12035:SF135 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 13 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017257.1|UniProtKB=W5NL36 W5NL36 PTHR11955:SF57 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, BRAIN fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014683.1|UniProtKB=W5NBS4 W5NBS4 PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;microtubule binding#GO:0008017;catalytic activity, acting on a protein#GO:0140096 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000721.1|UniProtKB=W5LXE1 W5LXE1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000482.1|UniProtKB=W5LWM2 W5LWM2 YPEL5 PTHR13848:SF56 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003235.1|UniProtKB=W5M610 W5M610 PTHR31705:SF5 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007340.1|UniProtKB=W5MKJ9 W5MKJ9 PTHR22967:SF10 SERINE/THREONINE PROTEIN KINASE BMP-2-INDUCIBLE PROTEIN KINASE phosphatase regulator activity#GO:0019208;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;regulation of multicellular organismal process#GO:0051239;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of Notch signaling pathway#GO:0008593;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of receptor-mediated endocytosis#GO:0048259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006731.1|UniProtKB=W5MIE0 W5MIE0 PTHR22168:SF3 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 LEPOC|Ensembl=ENSLOCG00000001880.1|UniProtKB=W5M1C0 W5M1C0 PTHR21470:SF2 RAB6-INTERACTING PROTEIN GORAB RAB6-INTERACTING GOLGIN LEPOC|Ensembl=ENSLOCG00000004236.1|UniProtKB=W5M9L0 W5M9L0 PAOX PTHR10742:SF405 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017331.1|UniProtKB=W5NLC7 W5NLC7 RNF183 PTHR22791:SF7 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF183 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006498.1|UniProtKB=W5MHJ0 W5MHJ0 PTHR24411:SF26 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR TRANSCRIPTION FACTOR NF-E2 45 KDA SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000000761.1|UniProtKB=W5LXI6 W5LXI6 PTHR25466:SF11 T-LYMPHOCYTE ACTIVATION ANTIGEN GALECTIN 17-RELATED response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002166.1|UniProtKB=W5M2A9 W5M2A9 PTHR21446:SF6 DUF3504 DOMAIN-CONTAINING PROTEIN MITOCHONDRIAL ANTIVIRAL-SIGNALING PROTEIN LEPOC|Ensembl=ENSLOCG00000014036.1|UniProtKB=W5N9J2 W5N9J2 PTHR10985:SF130 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY-RELATED 8A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017239.1|UniProtKB=W5NL13 W5NL13 PTHR13334:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN US10M cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009785.1|UniProtKB=W5MU88 W5MU88 PTHR10628:SF22 SIALIDASE SIALIDASE-4 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007879.1|UniProtKB=W5MMF9 W5MMF9 PTHR10517:SF25 FOLATE RECEPTOR RETBINDIN ISOFORM X1 signaling receptor activity#GO:0038023;transmembrane transporter activity#GO:0022857;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011538.1|UniProtKB=W5N0L6 W5N0L6 MTCH1 PTHR10780:SF3 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 1 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007871.1|UniProtKB=W5MME8 W5MME8 PTHR11532:SF92 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 CCKR signaling map#P06959>Carboxypeptidase E#P07026;Vasopressin synthesis#P04395>Exopeptidase#P04592 LEPOC|Ensembl=ENSLOCG00000009502.1|UniProtKB=W5MTA5 W5MTA5 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011786.1|UniProtKB=W5N1J1 W5N1J1 PTHR31882:SF3 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 1 response to external biotic stimulus#GO:0043207;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to lipopolysaccharide#GO:0071222;negative regulation of intracellular signal transduction#GO:1902532;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;regulation of macromolecule biosynthetic process#GO:0010556;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;response to lipopolysaccharide#GO:0032496;cellular response to molecule of bacterial origin#GO:0071219;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000001940.1|UniProtKB=W5M1I7 W5M1I7 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014051.1|UniProtKB=W5N9L1 W5N9L1 PTHR14624:SF0 DFG10 PROTEIN POLYPRENOL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular lipid catabolic process#GO:0044242;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;isoprenoid catabolic process#GO:0008300;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;isoprenoid biosynthetic process#GO:0008299;carbohydrate derivative biosynthetic process#GO:1901137;small molecule catabolic process#GO:0044282;protein N-linked glycosylation#GO:0006487;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005063.1|UniProtKB=W5MCI5 W5MCI5 PTHR12644:SF2 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Huntington disease#P00029>Arp2/3 complex#P00811 LEPOC|Ensembl=ENSLOCG00000017528.1|UniProtKB=W5NLX4 W5NLX4 PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of coagulation#GO:0050818;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of wound healing#GO:0061041;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;regulation of body fluid levels#GO:0050878;cell communication#GO:0007154;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of response to wounding#GO:1903034;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-1#P00404;Angiogenesis#P00005>PAR#P00192 LEPOC|Ensembl=ENSLOCG00000005767.1|UniProtKB=W5MF10 W5MF10 PTHR13230:SF5 GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;rDNA binding#GO:0000182 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000003840.1|UniProtKB=W5M878 W5M878 PTHR46255:SF1 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014785.1|UniProtKB=W5NC49 W5NC49 WNK3 PTHR13902:SF47 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;molecular function inhibitor activity#GO:0140678;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of sodium ion transport#GO:0002028;macromolecule modification#GO:0043412;regulation of metal ion transport#GO:0010959;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of monoatomic ion transport#GO:0043269;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016541.1|UniProtKB=W5NIG9 W5NIG9 PTHR46423:SF1 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;protein folding chaperone complex#GO:0101031 LEPOC|Ensembl=ENSLOCG00000009709.1|UniProtKB=W5MTZ6 W5MTZ6 PTHR15746:SF20 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 2 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002571.1|UniProtKB=W5M3R4 W5M3R4 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BARDET-BIEDL SYNDROME 1 PROTEIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000003645.1|UniProtKB=W5M7J2 W5M7J2 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017511.1|UniProtKB=W5NLV7 W5NLV7 PTHR13469:SF8 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 HEXIM P-TEFB COMPLEX SUBUNIT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;enzyme inhibitor activity#GO:0004857;snRNA binding#GO:0017069;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of protein kinase activity#GO:0006469;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of cell cycle#GO:0045786;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013281.1|UniProtKB=W5N6V8 W5N6V8 ANKS6 PTHR10627:SF70 SCP160 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010633.1|UniProtKB=W5MXA7 W5MXA7 C4orf33 PTHR31475:SF5 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 HOMOLOG LEPOC|Ensembl=ENSLOCG00000013512.1|UniProtKB=W5N7Q5 W5N7Q5 PTHR23413:SF1 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N RIBOSOMAL PROTEIN L32 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012464.1|UniProtKB=W5N3Z3 W5N3Z3 PTHR12625:SF1 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR LIMB REGION 1 PROTEIN HOMOLOG signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000952.1|UniProtKB=W5LY51 W5LY51 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015862.1|UniProtKB=W5NFX2 W5NFX2 PTHR21738:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000001375.1|UniProtKB=W5LZK4 W5LZK4 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006865.1|UniProtKB=W5MIU2 W5MIU2 PTHR14964:SF2 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR-BINDING FACTOR 2 process utilizing autophagic mechanism#GO:0061919;cellular metabolic process#GO:0044237;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011568.1|UniProtKB=W5N0Q3 W5N0Q3 PRLH2 PTHR17206:SF0 PROLACTIN-RELEASING PEPTIDE PRRP PROTEIN LEPOC|Ensembl=ENSLOCG00000005867.1|UniProtKB=W5MFC6 W5MFC6 PTHR19226:SF2 THY-1 MEMBRANE GLYCOPROTEIN THY-1 MEMBRANE GLYCOPROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell-matrix adhesion#GO:0001952;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell-substrate adhesion#GO:0010811;regulation of cellular component organization#GO:0051128;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;integrin-mediated signaling pathway#GO:0007229;positive regulation of cell adhesion#GO:0045785;regulation of cell junction assembly#GO:1901888;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810 somatodendritic compartment#GO:0036477;anchoring junction#GO:0070161;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;neuron projection#GO:0043005;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;membrane raft#GO:0045121;cell projection#GO:0042995;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016225.1|UniProtKB=W5NH96 W5NH96 PTHR43720:SF2 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000010009.1|UniProtKB=W5MV53 W5MV53 PTHR45796:SF3 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000009626.1|UniProtKB=W5MTQ7 W5MTQ7 PTHR46135:SF5 NME/NM23 FAMILY MEMBER 8 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000000075.1|UniProtKB=W5LVC7 W5LVC7 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000003701.1|UniProtKB=W5M7R7 W5M7R7 PTHR24403:SF67 ZINC FINGER PROTEIN FI01116P-RELATED regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013335.1|UniProtKB=W5N731 W5N731 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cell motility#GO:0048870;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;leukocyte migration#GO:0050900;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;cell differentiation#GO:0030154;lymphocyte migration#GO:0072676;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell migration#GO:0016477;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000006354.1|UniProtKB=W5MH13 W5MH13 PTHR45746:SF3 LP21163P REGULATOR OF G-PROTEIN SIGNALING 11 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000008201.1|UniProtKB=W5MNJ8 W5MNJ8 PTHR46110:SF2 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010706.1|UniProtKB=W5MXL0 W5MXL0 PTHR18945:SF335 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-6 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014989.1|UniProtKB=W5NCU4 W5NCU4 ITM2A PTHR10962:SF7 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2A amyloid-beta binding#GO:0001540;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007142.1|UniProtKB=W5MJV1 W5MJV1 PTHR24416:SF295 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;collagen binding#GO:0005518;molecular transducer activity#GO:0060089;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013543.1|UniProtKB=W5N7T5 W5N7T5 PTHR10219:SF19 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN 2 lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005475.1|UniProtKB=W5MDZ6 W5MDZ6 PTHR12493:SF0 CUE DOMAIN CONTAINING 2 CUE DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005314.1|UniProtKB=W5MDE5 W5MDE5 PTHR11547:SF19 ARGININE OR CREATINE KINASE CREATINE KINASE S-TYPE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000012427.1|UniProtKB=W5N3U0 W5N3U0 DNAJB6 PTHR43948:SF6 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 6 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000703.1|UniProtKB=W5LXC3 W5LXC3 PTHR37557:SF4 115 KDA PROTEIN IN TYPE-1 RETROTRANSPOSABLE ELEMENT R1DM-LIKE PROTEIN-RELATED-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000011087.1|UniProtKB=W5MZ14 W5MZ14 PTHR11742:SF40 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017173.1|UniProtKB=W5NKR7 W5NKR7 PTHR45725:SF7 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 2 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;positive regulation of Wnt signaling pathway#GO:0030177;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to stimulus#GO:0048584;negative regulation of multicellular organismal process#GO:0051241;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of nervous system development#GO:0051960;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000016379.1|UniProtKB=W5NHW8 W5NHW8 POC1B PTHR44019:SF1 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG B organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012625.1|UniProtKB=W5N4I5 W5N4I5 PTHR23040:SF1 FAMILY NOT NAMED OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000636.1|UniProtKB=W5LX73 W5LX73 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004981.1|UniProtKB=W5MC83 W5MC83 PTHR33772:SF1 THYMUS, BRAIN AND TESTES-ASSOCIATED PROTEIN TBATA LEPOC|Ensembl=ENSLOCG00000014209.1|UniProtKB=W5NA42 W5NA42 PTHR16089:SF23 REST COREPRESSOR COREST PROTEIN-RELATED ZINC FINGER PROTEIN 541 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012971.1|UniProtKB=W5N5S4 W5N5S4 PTHR11347:SF85 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;response to growth factor#GO:0070848;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000007393.1|UniProtKB=W5MKR2 W5MKR2 PTHR46679:SF1 FAMILY NOT NAMED GLUTAREDOXIN-2, MITOCHONDRIAL protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000004865.1|UniProtKB=W5MBT5 W5MBT5 PTHR10489:SF931 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 3 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010776.1|UniProtKB=W5MXU4 W5MXU4 PTHR45619:SF44 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway#P00059>PP2A#P04630;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway feedback loops 2#P04398>PP2A-C#P04659;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000003345.1|UniProtKB=W5M6E0 W5M6E0 PTHR46723:SF1 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000004723.1|UniProtKB=W5MB96 W5MB96 PTHR12522:SF3 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 503 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001316.1|UniProtKB=W5LZE4 W5LZE4 PTHR11849:SF171 ETS ETS HOMOLOGOUS FACTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000004779.1|UniProtKB=W5MBH3 W5MBH3 PTHR21146:SF0 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 p38 MAPK pathway#P05918>MEF#P06023 LEPOC|Ensembl=ENSLOCG00000012670.1|UniProtKB=W5N4N4 W5N4N4 PTHR10838:SF19 SYNAPTOGYRIN SYNAPTOGYRIN-2 LIKE PROTEIN-RELATED synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001541.1|UniProtKB=W5M056 W5M056 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001388.1|UniProtKB=W5LZM3 W5LZM3 PTHR11958:SF93 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 LEPOC|Ensembl=ENSLOCG00000004557.1|UniProtKB=W5MAQ9 W5MAQ9 PTHR14398:SF2 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 26 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014666.1|UniProtKB=W5NBP1 W5NBP1 PTHR34648:SF7 CLOCK-INTERACTING PACEMAKER SI:CH211-132B12.7 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008555.1|UniProtKB=W5MPU6 W5MPU6 PTHR10117:SF25 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000013968.1|UniProtKB=W5N9A7 W5N9A7 PTHR33963:SF2 MKRN2 OPPOSITE STRAND PROTEIN MKRN2 OPPOSITE STRAND PROTEIN LEPOC|Ensembl=ENSLOCG00000008073.1|UniProtKB=W5MN42 W5MN42 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007500.1|UniProtKB=W5ML45 W5ML45 PTHR23189:SF46 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 1 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006686.1|UniProtKB=W5MI63 W5MI63 PTHR19139:SF177 AQUAPORIN TRANSPORTER AQUAPORIN 14 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006219.1|UniProtKB=W5MGK0 W5MGK0 PTHR32005:SF3 TRANSMEMBRANE PROTEIN 178B-RELATED SI:CH211-150G13.3-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010282.1|UniProtKB=W5MW28 W5MW28 C5orf15 PTHR16502:SF0 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000007949.1|UniProtKB=W5MMP8 W5MMP8 PTHR12411:SF856 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN S, ORTHOLOG 1 ISOFORM X1 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013231.1|UniProtKB=W5N6Q2 W5N6Q2 FLNB PTHR38537:SF7 JITTERBUG, ISOFORM N FILAMIN-B Integrin signalling pathway#P00034>Filamin#P00914 LEPOC|Ensembl=ENSLOCG00000010081.1|UniProtKB=W5MVC4 W5MVC4 PTHR46290:SF1 DI-N-ACETYLCHITOBIASE DI-N-ACETYLCHITOBIASE LEPOC|Ensembl=ENSLOCG00000010889.1|UniProtKB=W5MY97 W5MY97 SLC39A12 PTHR12191:SF4 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP12 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001289.1|UniProtKB=W5LZA3 W5LZA3 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015071.1|UniProtKB=W5ND37 W5ND37 PTHR10822:SF4 GLYPICAN GLYPICAN-3 regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of protein localization to membrane#GO:1905475;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;regulation of cellular localization#GO:0060341;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004632.1|UniProtKB=W5MAZ1 W5MAZ1 PTHR12383:SF16 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002567.1|UniProtKB=W5M3S4 W5M3S4 PTHR24271:SF52 KALLIKREIN-RELATED GRANZYME K serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003961.1|UniProtKB=W5M8M6 W5M8M6 PTHR10125:SF4 P2X PURINOCEPTOR P2X PURINOCEPTOR 2 monoatomic cation channel activity#GO:0005261;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009617.1|UniProtKB=W5MTP3 W5MTP3 PTHR32343:SF6 SERINE/ARGININE-RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 11 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013419.1|UniProtKB=W5N7E0 W5N7E0 PTHR19277:SF24 PENTRAXIN NEURONAL PENTRAXIN-1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008957.1|UniProtKB=W5MRD0 W5MRD0 PTHR24023:SF845 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013887.1|UniProtKB=W5N925 W5N925 PTHR18929:SF101 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000270.1|UniProtKB=W5LVY8 W5LVY8 PTHR14098:SF17 SH2 DOMAIN CONTAINING PROTEIN B-CELL LINKER PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004161.1|UniProtKB=W5M9B4 W5M9B4 PTHR13050:SF7 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;SNARE complex#GO:0031201;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015329.1|UniProtKB=W5NE03 W5NE03 PTHR15286:SF9 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012478.1|UniProtKB=W5N401 W5N401 PTHR10491:SF4 DTDP-4-DEHYDRORHAMNOSE REDUCTASE METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA reductase#PC00198;oxidoreductase#PC00176 O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose reductase#P03050 LEPOC|Ensembl=ENSLOCG00000003004.1|UniProtKB=W5M584 W5M584 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014801.1|UniProtKB=W5NC68 W5NC68 OTUD7A PTHR13367:SF9 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7A cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;protein K63-linked deubiquitination#GO:0070536;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004044.1|UniProtKB=W5M8W7 W5M8W7 PTHR23003:SF65 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012214.1|UniProtKB=W5N351 W5N351 PTHR45836:SF9 SLIT HOMOLOG SLIT HOMOLOG 3 PROTEIN heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 LEPOC|Ensembl=ENSLOCG00000017483.1|UniProtKB=W5NLS9 W5NLS9 PTHR24072:SF150 RHO FAMILY GTPASE RHOG FAMILY MEMBER 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Rac#P00564 LEPOC|Ensembl=ENSLOCG00000012850.1|UniProtKB=W5N5A5 W5N5A5 PTHR24055:SF596 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017851.1|UniProtKB=W5NMU5 W5NMU5 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001517.1|UniProtKB=W5M022 W5M022 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003399.1|UniProtKB=W5M6L6 W5M6L6 PTHR10989:SF17 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-DEPENDENT TFPI-REGULATING PROTEIN cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000013575.1|UniProtKB=W5N7X6 W5N7X6 PTHR13177:SF3 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;response to extracellular stimulus#GO:0009991;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;apoptotic process#GO:0006915;cell death#GO:0008219;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;cellular response to stimulus#GO:0051716;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;programmed cell death#GO:0012501;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;response to nutrient levels#GO:0031667;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;negative regulation of catabolic process#GO:0009895;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000003796.1|UniProtKB=W5M821 W5M821 PTHR14491:SF3 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHB LEPOC|Ensembl=ENSLOCG00000005273.1|UniProtKB=W5MD93 W5MD93 PTHR24028:SF244 CADHERIN-87A PARAXIAL PROTOCADHERIN cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000003926.1|UniProtKB=W5M8I5 W5M8I5 PTHR24396:SF21 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 236 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004371.1|UniProtKB=W5MA11 W5MA11 ZNF821 PTHR24404:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 821 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003553.1|UniProtKB=W5M746 W5M746 PTHR24246:SF18 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;system process#GO:0003008;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000013730.1|UniProtKB=W5N8H7 W5N8H7 PTHR10151:SF66 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE ENPP6 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002822.1|UniProtKB=W5M4L2 W5M4L2 PTHR10498:SF10 PARALEMMIN-RELATED PALM2 AND AKAP2 FUSION-RELATED LEPOC|Ensembl=ENSLOCG00000002106.1|UniProtKB=W5M233 W5M233 PTHR22799:SF3 TETRANECTIN-RELATED TETRANECTIN ossification#GO:0001503;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;biomineral tissue development#GO:0031214;multicellular organismal process#GO:0032501;bone mineralization#GO:0030282;tissue development#GO:0009888 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000017697.1|UniProtKB=W5NME3 W5NME3 PTHR24228:SF25 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B2 BRADYKININ RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000010831.1|UniProtKB=W5MY22 W5MY22 PTHR11388:SF87 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2B1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;bile acid transmembrane transporter activity#GO:0015125;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004675.1|UniProtKB=W5MB40 W5MB40 PTHR48032:SF10 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016155.1|UniProtKB=W5NH05 W5NH05 PTHR10846:SF42 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007818.1|UniProtKB=W5MM81 W5MM81 PTHR10628:SF25 SIALIDASE SIALIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008415.1|UniProtKB=W5MPD5 W5MPD5 PTHR24025:SF20 DESMOGLEIN FAMILY MEMBER DACHSOUS CADHERIN RELATED 2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000016516.1|UniProtKB=W5NIE2 W5NIE2 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000001231.1|UniProtKB=W5LZ36 W5LZ36 PTHR24394:SF48 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 771 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009777.1|UniProtKB=W5MU84 W5MU84 PTHR44666:SF1 WD REPEAT-CONTAINING PROTEIN 53 WD REPEAT-CONTAINING PROTEIN 53 LEPOC|Ensembl=ENSLOCG00000017642.1|UniProtKB=W5NM88 W5NM88 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005265.1|UniProtKB=W5MD80 W5MD80 PTHR13720:SF13 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251 membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012840.1|UniProtKB=W5N592 W5N592 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015097.1|UniProtKB=W5ND75 W5ND75 PTHR11607:SF57 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2X hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006603.1|UniProtKB=W5MHW2 W5MHW2 PTHR11954:SF22 D-DOPACHROME DECARBOXYLASE D-DOPACHROME DECARBOXYLASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 decarboxylase#PC00089;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000013757.1|UniProtKB=W5N8K7 W5N8K7 PTHR18945:SF579 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT THETA signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004579.1|UniProtKB=W5MAT0 W5MAT0 PTHR24083:SF184 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;intracellular receptor signaling pathway#GO:0030522;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004945.1|UniProtKB=W5MC38 W5MC38 PTHR46103:SF1 RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000009420.1|UniProtKB=W5MSY5 W5MSY5 PTHR10024:SF114 SYNAPTOTAGMIN SYNAPTOTAGMIN-4 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Gonadotropin-releasing hormone receptor pathway#P06664>Syt IV#P06746 LEPOC|Ensembl=ENSLOCG00000016579.1|UniProtKB=W5NIL9 W5NIL9 PTHR11695:SF294 ALCOHOL DEHYDROGENASE RELATED RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017311.1|UniProtKB=W5NLA7 W5NLA7 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003308.1|UniProtKB=W5M6A0 W5M6A0 PTHR46500:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016760.1|UniProtKB=W5NJA6 W5NJA6 PTHR10270:SF210 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-7 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000005093.1|UniProtKB=W5MCM6 W5MCM6 PTHR22847:SF626 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 38 LEPOC|Ensembl=ENSLOCG00000001258.1|UniProtKB=W5LZ69 W5LZ69 PTHR15168:SF0 CYTOCHROME B-245 LIGHT CHAIN CYTOCHROME B-245 LIGHT CHAIN LEPOC|Ensembl=ENSLOCG00000016733.1|UniProtKB=W5NJ66 W5NJ66 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013458.1|UniProtKB=W5N7I5 W5N7I5 RHBDF2 PTHR45965:SF2 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 2 regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of cellular localization#GO:0060341;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of ERBB signaling pathway#GO:1901184;regulation of protein transport#GO:0051223;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011674.1|UniProtKB=W5N136 W5N136 PTHR17103:SF15 NEUREXOPHILIN NEUREXOPHILIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012823.1|UniProtKB=W5N569 W5N569 PTHR21545:SF14 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT COREPRESSOR regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010015.1|UniProtKB=W5MV38 W5MV38 PTHR11866:SF10 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;system process#GO:0003008;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of localization#GO:0032879;negative regulation of transport#GO:0051051;regulation of system process#GO:0044057;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;response to stimulus#GO:0050896;regulation of transport#GO:0051049;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;defense response#GO:0006952;signaling#GO:0023052;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 LEPOC|Ensembl=ENSLOCG00000011479.1|UniProtKB=W5N0F4 W5N0F4 MOK PTHR24055:SF533 MITOGEN-ACTIVATED PROTEIN KINASE MAPK_MAK_MRK OVERLAPPING KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008386.1|UniProtKB=W5MP85 W5MP85 PTHR10878:SF6 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;chordate embryonic development#GO:0043009;response to stimulus#GO:0050896;embryo development#GO:0009790;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Wnt signaling pathway#P00057>Dishevelled#P01447 LEPOC|Ensembl=ENSLOCG00000007691.1|UniProtKB=W5MLT1 W5MLT1 PTHR24042:SF8 NEL HOMOLOG SUBFAMILY NOT NAMED heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000015766.1|UniProtKB=W5NFK0 W5NFK0 TRIM67 PTHR24099:SF21 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 67 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003523.1|UniProtKB=W5M718 W5M718 PTHR19269:SF40 TROPOMYOSIN TROPOMYOSIN 4-2ALPHA cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000010568.1|UniProtKB=W5MX44 W5MX44 PTHR11006:SF92 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 2 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;protein metabolic process#GO:0019538;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000964.1|UniProtKB=W5LY69 W5LY69 PTHR24228:SF10 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR 15 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004802.1|UniProtKB=W5MBK6 W5MBK6 PTHR19282:SF25 TETRASPANIN UROPLAKIN-1A cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010647.1|UniProtKB=W5MXC8 W5MXC8 PTHR14491:SF2 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000010231.1|UniProtKB=W5MVX0 W5MVX0 PTHR23244:SF456 KELCH REPEAT DOMAIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000000315.1|UniProtKB=W5LW34 W5LW34 PTHR25465:SF5 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003979.1|UniProtKB=W5M8P1 W5M8P1 PTHR14429:SF5 FIBROSIN FAMILY MEMBER AUTISM SUSCEPTIBILITY GENE 2 PROTEIN LEPOC|Ensembl=ENSLOCG00000012780.1|UniProtKB=W5N521 W5N521 PTHR14890:SF1 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006876.1|UniProtKB=W5MIV9 W5MIV9 PTHR24410:SF40 HL07962P-RELATED SI:DKEY-229B18.3 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003186.1|UniProtKB=W5M5W2 W5M5W2 PTHR23349:SF59 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST PANCREAS TRANSCRIPTION FACTOR 1 SUBUNIT ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000018000.1|UniProtKB=W5NN92 W5NN92 TLR5 PTHR24365:SF525 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004019.1|UniProtKB=W5M8U3 W5M8U3 PTHR10336:SF102 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000003889.1|UniProtKB=W5M8D2 W5M8D2 PTHR46271:SF2 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINA AND ANTERIOR NEURAL FOLD HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005313.1|UniProtKB=W5MDG5 W5MDG5 PTHR22692:SF24 MYOSIN VII, XV MYOSIN VIIB actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000013310.1|UniProtKB=W5N6Z2 W5N6Z2 PTHR19969:SF15 SH2-SH3 ADAPTOR PROTEIN-RELATED SRC-LIKE-ADAPTER 2 ISOFORM X1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007222.1|UniProtKB=W5MK35 W5MK35 PTHR19304:SF9 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Ras Pathway#P04393>ATF2#P04548;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Gonadotropin-releasing hormone receptor pathway#P06664>ATF2#P06732;Apoptosis signaling pathway#P00006>ATF#P00302;Oxidative stress response#P00046>ATF2#P01126;CCKR signaling map#P06959>ATF2#P07078 LEPOC|Ensembl=ENSLOCG00000016242.1|UniProtKB=W5NHB7 W5NHB7 PTHR16650:SF10 C21ORF13-RELATED LEBERCILIN cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000009972.1|UniProtKB=W5MUZ9 W5MUZ9 PTHR24040:SF0 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN VITAMIN K-DEPENDENT PROTEIN S extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 Blood coagulation#P00011>PS#P00412 LEPOC|Ensembl=ENSLOCG00000005157.1|UniProtKB=W5MCU9 W5MCU9 PTHR11232:SF79 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008474.1|UniProtKB=W5MPK4 W5MPK4 PTHR13220:SF11 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;intracellular signal transduction#GO:0035556;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006125.1|UniProtKB=W5MG97 W5MG97 CALML6 PTHR23064:SF31 TROPONIN CALMODULIN LIKE 6 multicellular organismal process#GO:0032501;nervous system process#GO:0050877;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007888.1|UniProtKB=W5MMH5 W5MMH5 PTHR11818:SF54 BETA/GAMMA CRYSTALLIN BETAA1C-CRYSTALLIN-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013024.1|UniProtKB=W5N5Y0 W5N5Y0 PTHR14647:SF57 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017445.1|UniProtKB=W5NLP1 W5NLP1 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013772.1|UniProtKB=W5N8M3 W5N8M3 PTHR15031:SF3 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012621.1|UniProtKB=W5N4I3 W5N4I3 PTHR10663:SF329 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 2 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003464.1|UniProtKB=W5M6W5 W5M6W5 PTHR12385:SF42 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013471.1|UniProtKB=W5N7K9 W5N7K9 DCAF1 PTHR13129:SF4 VPRBP PROTEIN-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 1 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000016497.1|UniProtKB=W5NIB7 W5NIB7 PTHR45813:SF4 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009690.1|UniProtKB=W5MTX5 W5MTX5 PTHR23226:SF404 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 432 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007807.1|UniProtKB=W5MM90 W5MM90 PTHR24006:SF655 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018225.1|UniProtKB=W5NNW7 W5NNW7 PTHR24381:SF445 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF28.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005105.1|UniProtKB=W5MCN6 W5MCN6 PTHR45787:SF5 LD11652P LIM DOMAIN TRANSCRIPTION FACTOR LMO4 LEPOC|Ensembl=ENSLOCG00000006256.1|UniProtKB=W5MGP5 W5MGP5 EBI3 PTHR48483:SF2 INTERLEUKIN-27 SUBUNIT BETA INTERLEUKIN-27 SUBUNIT BETA LEPOC|Ensembl=ENSLOCG00000010614.1|UniProtKB=W5MX94 W5MX94 PTHR24028:SF0 CADHERIN-87A PROTOCADHERIN-10 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000013557.1|UniProtKB=W5N7V6 W5N7V6 IKZF3 PTHR24404:SF23 ZINC FINGER PROTEIN ZINC FINGER PROTEIN AIOLOS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001143.1|UniProtKB=W5LZ11 W5LZ11 PTHR44170:SF15 PROTEIN SIDEKICK NEURONAL CELL ADHESION MOLECULE cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;head development#GO:0060322;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000632.1|UniProtKB=W5LX40 W5LX40 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007681.1|UniProtKB=W5MLR5 W5MLR5 PTHR31302:SF0 TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN LEPOC|Ensembl=ENSLOCG00000009232.1|UniProtKB=W5MS99 W5MS99 PTHR11551:SF5 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 2 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011848.1|UniProtKB=W5N1R3 W5N1R3 PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017446.1|UniProtKB=W5NLP2 W5NLP2 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002511.1|UniProtKB=W5M3L7 W5M3L7 SPNS2 PTHR23505:SF4 SPINSTER SPHINGOSINE-1-PHOSPHATE TRANSPORTER SPNS2 transporter activity#GO:0005215;lipid transporter activity#GO:0005319 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;macromolecule localization#GO:0033036;transport#GO:0006810;cell communication#GO:0007154;cellular process#GO:0009987;lipid transport#GO:0006869;regulation of biological process#GO:0050789;localization#GO:0051179;organic substance transport#GO:0071702;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;lipid localization#GO:0010876;signaling#GO:0023052 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003198.1|UniProtKB=W5M5X7 W5M5X7 PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000003687.1|UniProtKB=W5M7L9 W5M7L9 PTHR24248:SF140 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE RECEPTOR H3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006558.1|UniProtKB=W5MHR2 W5MHR2 PTHR24390:SF135 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 740 ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003047.1|UniProtKB=W5M5G0 W5M5G0 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009620.1|UniProtKB=W5MTP2 W5MTP2 PTHR16705:SF6 COMPLEXIN COMPLEXIN-1 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;SNARE complex#GO:0031201;cell junction#GO:0030054;terminal bouton#GO:0043195;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000005297.1|UniProtKB=W5MDC5 W5MDC5 IGLON5 PTHR42757:SF12 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED IGLON FAMILY MEMBER 5 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001794.1|UniProtKB=W5M121 W5M121 PTHR13936:SF15 PROFILIN PROFILIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of anatomical structure size#GO:0090066;positive regulation of organelle organization#GO:0010638;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;positive regulation of actin filament bundle assembly#GO:0032233;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of actin filament bundle assembly#GO:0032231 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 LEPOC|Ensembl=ENSLOCG00000012323.1|UniProtKB=W5N3F8 W5N3F8 PTHR19432:SF34 SUGAR TRANSPORTER MEMBRANE-ASSOCIATED TRANSPORTER PROTEIN solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;carbohydrate transmembrane transporter activity#GO:0015144;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008051.1|UniProtKB=W5MN18 W5MN18 PTHR18945:SF889 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-10 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000018039.1|UniProtKB=W5NND1 W5NND1 PTHR10656:SF38 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MAB21L1-RELATED transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016850.1|UniProtKB=W5NJM2 W5NJM2 PTHR11727:SF17 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;aromatic compound biosynthetic process#GO:0019438;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000017407.1|UniProtKB=W5NLK3 W5NLK3 PTHR10704:SF3 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017834.1|UniProtKB=W5NMS8 W5NMS8 PTHR36471:SF1 SMALL MEMBRANE A-KINASE ANCHOR PROTEIN SMALL MEMBRANE A-KINASE ANCHOR PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002858.1|UniProtKB=W5M4V5 W5M4V5 PTHR10878:SF5 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;chordate embryonic development#GO:0043009;response to stimulus#GO:0050896;embryo development#GO:0009790;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Wnt signaling pathway#P00057>Dishevelled#P01447 LEPOC|Ensembl=ENSLOCG00000015005.1|UniProtKB=W5NCW6 W5NCW6 PTHR22761:SF21 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 7 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005164.1|UniProtKB=W5MCV9 W5MCV9 PTHR24323:SF3 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013090.1|UniProtKB=W5N666 W5N666 PTHR10285:SF143 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000015272.1|UniProtKB=W5NDT4 W5NDT4 PTHR11455:SF16 CRYPTOCHROME CRYPTOCHROME-1 nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deoxyribodipyrimidine photo-lyase activity#GO:0003904;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501 LEPOC|Ensembl=ENSLOCG00000007537.1|UniProtKB=W5ML84 W5ML84 PTHR16048:SF3 MSL2-RELATED E3 UBIQUITIN-PROTEIN LIGASE MSL2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000004333.1|UniProtKB=W5M9X7 W5M9X7 PAN2 PTHR15728:SF0 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000015577.1|UniProtKB=W5NEW9 W5NEW9 PTHR16089:SF13 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016781.1|UniProtKB=W5NJD5 W5NJD5 PTHR47507:SF2 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR-LIKE PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011556.1|UniProtKB=W5N0N8 W5N0N8 PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;double-stranded DNA binding#GO:0003690;exonuclease activity#GO:0004527;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;double-stranded RNA binding#GO:0003725 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001970.1|UniProtKB=W5M1N5 W5M1N5 SLC6A20 PTHR11616:SF44 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER XTRP3 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000011344.1|UniProtKB=W5MZY8 W5MZY8 LAMB3 PTHR10574:SF268 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-3 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000008733.1|UniProtKB=W5MQG8 W5MQG8 PTHR22882:SF3 SYNPHILIN-1 SYNPHILIN-1 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 Parkinson disease#P00049>Synphilin#P01225 LEPOC|Ensembl=ENSLOCG00000012717.1|UniProtKB=W5N4U5 W5N4U5 PTHR10378:SF48 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 1-RELATED protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004120.1|UniProtKB=W5M968 W5M968 PTHR12113:SF8 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 3 signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003038.1|UniProtKB=W5M5B3 W5M5B3 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012058.1|UniProtKB=W5N2H4 W5N2H4 PTHR23240:SF6 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED DNA CROSS-LINK REPAIR 1A PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008937.1|UniProtKB=W5MR76 W5MR76 PTHR11829:SF340 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN H1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000013917.1|UniProtKB=W5N945 W5N945 PTHR37984:SF15 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009851.1|UniProtKB=W5MUK5 W5MUK5 PTHR43690:SF18 NARDILYSIN INSULIN-DEGRADING ENZYME-RELATED metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002622.1|UniProtKB=W5M3X7 W5M3X7 PTHR14470:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010039.1|UniProtKB=W5MV74 W5MV74 PTHR45646:SF4 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;peptidyl-tyrosine modification#GO:0018212;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014350.1|UniProtKB=W5NAL2 W5NAL2 PTHR11309:SF133 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>FrzB#P01461 LEPOC|Ensembl=ENSLOCG00000004315.1|UniProtKB=W5M9Y0 W5M9Y0 PTHR45615:SF29 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7B microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000004200.1|UniProtKB=W5M9F5 W5M9F5 PTHR23150:SF33 SULFATASE MODIFYING FACTOR 1, 2 INACTIVE C-ALPHA-FORMYLGLYCINE-GENERATING ENZYME 2 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012319.1|UniProtKB=W5N3F0 W5N3F0 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000017072.1|UniProtKB=W5NKD9 W5NKD9 PTHR45955:SF1 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000011438.1|UniProtKB=W5N0A4 W5N0A4 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>19S proteasome#P01209;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000004931.1|UniProtKB=W5MC30 W5MC30 PTHR47835:SF3 HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG HELICASE FOR MEIOSIS 1 LEPOC|Ensembl=ENSLOCG00000010913.1|UniProtKB=W5MYC0 W5MYC0 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009171.1|UniProtKB=W5MS26 W5MS26 PTHR43677:SF4 SHORT-CHAIN DEHYDROGENASE/REDUCTASE QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000015954.1|UniProtKB=W5NG86 W5NG86 PTHR46787:SF1 SYNDROMES PUTATIVE CHAPERONIN-RELATED MOLECULAR CHAPERONE MKKS cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;protein-containing complex assembly#GO:0065003;chaperone-mediated protein complex assembly#GO:0051131;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;stereocilium bundle#GO:0032421;kinocilium#GO:0060091;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009103.1|UniProtKB=W5MRZ0 W5MRZ0 PTHR10063:SF3 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000006365.1|UniProtKB=W5MH21 W5MH21 PTHR45771:SF13 HOMEOTIC PROTEIN DEFORMED HOMEOBOX C5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000000606.1|UniProtKB=W5LX09 W5LX09 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007490.1|UniProtKB=W5ML32 W5ML32 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016403.1|UniProtKB=W5NHZ8 W5NHZ8 PTHR10183:SF302 CALPAIN CALPAIN-14 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008630.1|UniProtKB=W5MQ51 W5MQ51 PTHR46877:SF6 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000018354.1|UniProtKB=W5NP96 W5NP96 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016694.1|UniProtKB=W5NJ15 W5NJ15 PTHR10265:SF9 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1B protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;binding#GO:0005488;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;protein-folding chaperone binding#GO:0051087;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of cell population proliferation#GO:0008285;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase inhibitor#PC00139 Interleukin signaling pathway#P00036>p27KIP1#P00982 LEPOC|Ensembl=ENSLOCG00000003233.1|UniProtKB=W5M618 W5M618 PTHR16517:SF20 TUBBY-RELATED TUBBY PROTEIN HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002186.1|UniProtKB=W5M2D5 W5M2D5 PTHR15193:SF1 CD83 ANTIGEN CD83 ANTIGEN LEPOC|Ensembl=ENSLOCG00000012917.1|UniProtKB=W5N5L0 W5N5L0 PTHR24085:SF8 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005954.1|UniProtKB=W5MFN1 W5MFN1 PTHR12271:SF40 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000009583.1|UniProtKB=W5MTL8 W5MTL8 PTHR48051:SF39 FAMILY NOT NAMED P53-INDUCED DEATH DOMAIN PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015869.1|UniProtKB=W5NFY0 W5NFY0 PTHR44027:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5G chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012267.1|UniProtKB=W5N3A0 W5N3A0 PTHR15597:SF25 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;multicellular organism development#GO:0007275;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008308.1|UniProtKB=W5MNY4 W5MNY4 PTHR10625:SF19 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 12 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000016956.1|UniProtKB=W5NK05 W5NK05 EPHA7 PTHR46877:SF9 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 7 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004893.1|UniProtKB=W5MBY4 W5MBY4 PTHR11566:SF32 DYNAMIN DYNAMIN-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;receptor internalization#GO:0031623;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of organelle localization#GO:0051656;vesicle-mediated transport in synapse#GO:0099003 supramolecular complex#GO:0099080;synapse#GO:0045202;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Gonadotropin-releasing hormone receptor pathway#P06664>Dnm1#P06781;CCKR signaling map#P06959>Dynamin#P07100 LEPOC|Ensembl=ENSLOCG00000012261.1|UniProtKB=W5N380 W5N380 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 LEPOC|Ensembl=ENSLOCG00000003260.1|UniProtKB=W5M670 W5M670 PTHR22741:SF11 P140CAP/SNIP-RELATED SICKLE TAIL PROTEIN HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005473.1|UniProtKB=W5MDZ5 W5MDZ5 PTHR12107:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-3 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;channel regulator activity#GO:0016247;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;system process#GO:0003008;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;receptor-mediated endocytosis#GO:0006898;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;protein localization to organelle#GO:0033365;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;positive regulation of biological process#GO:0048518;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;vacuolar transport#GO:0007034;endocytosis#GO:0006897;protein localization to vacuole#GO:0072665;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;positive regulation of synaptic transmission#GO:0050806;import into cell#GO:0098657;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004121.1|UniProtKB=W5M990 W5M990 PTHR28630:SF28 FAMILY NOT NAMED PROSTAMIDE_PROSTAGLANDIN F SYNTHASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000001932.1|UniProtKB=W5M1H7 W5M1H7 PTHR45476:SF7 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL 3 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015653.1|UniProtKB=W5NF59 W5NF59 PTHR14304:SF12 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011032.1|UniProtKB=W5MYT8 W5MYT8 PTHR13944:SF22 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 28 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 CCKR signaling map#P06959>p190RhoGEF#P07157 LEPOC|Ensembl=ENSLOCG00000009223.1|UniProtKB=W5MS96 W5MS96 PTHR10554:SF11 SYNTROPHIN BETA-1-SYNTROPHIN membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014734.1|UniProtKB=W5NBY2 W5NBY2 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;external encapsulating structure organization#GO:0045229;regulation of molecular function#GO:0065009;supramolecular fiber organization#GO:0097435;regulation of hydrolase activity#GO:0051336;regulation of proteolysis#GO:0030162;collagen fibril organization#GO:0030199;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000015829.1|UniProtKB=W5NFS7 W5NFS7 PTHR10048:SF119 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000009654.1|UniProtKB=W5MTT6 W5MTT6 PTHR46053:SF3 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF4 aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005368.1|UniProtKB=W5MDL1 W5MDL1 GFM2 PTHR43261:SF1 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle organization#GO:0006996 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009842.1|UniProtKB=W5MUG9 W5MUG9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005153.1|UniProtKB=W5MCU4 W5MCU4 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002599.1|UniProtKB=W5M3U8 W5M3U8 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000011489.1|UniProtKB=W5N0G6 W5N0G6 PTHR13710:SF152 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q5 ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007208.1|UniProtKB=W5MK13 W5MK13 PTHR11486:SF23 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 5 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000005835.1|UniProtKB=W5MF86 W5MF86 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011591.1|UniProtKB=W5N0T6 W5N0T6 ADAMTSL1 PTHR13723:SF157 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003973.1|UniProtKB=W5M8P0 W5M8P0 PTHR10285:SF222 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000013979.1|UniProtKB=W5N9C2 W5N9C2 PTHR12659:SF2 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 7 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000010676.1|UniProtKB=W5MXG7 W5MXG7 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013489.1|UniProtKB=W5N7N2 W5N7N2 PTHR11254:SF282 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;molecular function regulator activity#GO:0098772;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;molecular function inhibitor activity#GO:0140678 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of dendrite development#GO:0050773;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;protein catabolic process#GO:0030163;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of monoatomic cation transmembrane transport#GO:1904062;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;regulation of monoatomic ion transmembrane transport#GO:0034765;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;negative regulation of transport#GO:0051051;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;neuromuscular junction development#GO:0007528;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;regulation of cell projection organization#GO:0031344;import into cell#GO:0098657;negative regulation of biological process#GO:0048519;receptor internalization#GO:0031623;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule modification#GO:0043412;transport#GO:0006810;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of transport#GO:0051049;catabolic process#GO:0009056;receptor-mediated endocytosis#GO:0006898;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;localization#GO:0051179;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000002819.1|UniProtKB=W5M4K8 W5M4K8 PTHR11486:SF83 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of kinase activity#GO:0033674;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000007418.1|UniProtKB=W5MKV5 W5MKV5 PTHR23122:SF39 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 7 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to cell junction#GO:1902414;protein localization#GO:0008104 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016170.1|UniProtKB=W5NH17 W5NH17 PTHR47958:SF195 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000001518.1|UniProtKB=W5M026 W5M026 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009343.1|UniProtKB=W5MSN9 W5MSN9 PTHR24020:SF29 COLLAGEN ALPHA COLLAGEN ALPHA-2(VI) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000009013.1|UniProtKB=W5MRH8 W5MRH8 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004150.1|UniProtKB=W5M9A4 W5M9A4 PTHR11848:SF277 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000010087.1|UniProtKB=W5MVD7 W5MVD7 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 cellular anatomical entity#GO:0110165;organelle membrane contact site#GO:0044232;organelle#GO:0043226;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000014611.1|UniProtKB=W5NBH2 W5NBH2 PTHR10155:SF18 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 9 ISOFORM X1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000003654.1|UniProtKB=W5M7J3 W5M7J3 PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016993.1|UniProtKB=W5NK49 W5NK49 PTHR11570:SF0 S-ADENOSYLMETHIONINE DECARBOXYLASE S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME decarboxylase#PC00089;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000015595.1|UniProtKB=W5NEZ1 W5NEZ1 PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017393.1|UniProtKB=W5NLI9 W5NLI9 PTHR11232:SF36 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000378.1|UniProtKB=W5LWA7 W5LWA7 PTHR11949:SF2 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Toll receptor signaling pathway#P00054>IRF3#P01374 LEPOC|Ensembl=ENSLOCG00000015342.1|UniProtKB=W5NE19 W5NE19 PTHR11848:SF39 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 10 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000002809.1|UniProtKB=W5M4K5 W5M4K5 PTHR11062:SF381 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2 acetylglucosaminyltransferase activity#GO:0008375;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009802.1|UniProtKB=W5MUE6 W5MUE6 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008760.1|UniProtKB=W5MQJ9 W5MQJ9 PTHR24241:SF183 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000014033.1|UniProtKB=W5N9J1 W5N9J1 PTHR10625:SF23 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 11 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000000765.1|UniProtKB=W5LXK4 W5LXK4 PTHR24343:SF567 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE BRSK2 ISOFORM X1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010819.1|UniProtKB=W5MY04 W5MY04 PTHR18935:SF7 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000008834.1|UniProtKB=W5MQU0 W5MQU0 PTHR11211:SF13 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009591.1|UniProtKB=W5MTK6 W5MTK6 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017537.1|UniProtKB=W5NLY3 W5NLY3 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003565.1|UniProtKB=W5M761 W5M761 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000000419.1|UniProtKB=W5LWE9 W5LWE9 PTHR11440:SF47 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHOLIPASE A2 GROUP XV carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000012232.1|UniProtKB=W5N339 W5N339 RUNDC1 PTHR15591:SF19 RUN AND SH3 DOMAIN CONTAINING RUN DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000008789.1|UniProtKB=W5MQP1 W5MQP1 PTHR13693:SF79 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 2 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016514.1|UniProtKB=W5NID9 W5NID9 PTHR46987:SF1 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-3 LEPOC|Ensembl=ENSLOCG00000001299.1|UniProtKB=W5LZB5 W5LZB5 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012459.1|UniProtKB=W5N3Y0 W5N3Y0 PTHR31395:SF4 SHISA PROTEIN SHISA-3 HOMOLOG scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004415.1|UniProtKB=W5MA67 W5MA67 PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016122.1|UniProtKB=W5NGV5 W5NGV5 PTHR19332:SF1 PEROXISOMAL MEMBRANE PROTEIN PEX13 PEROXISOMAL MEMBRANE PROTEIN PEX13 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011201.1|UniProtKB=W5MZF8 W5MZF8 PTHR48066:SF1 CARNOSINE SYNTHASE 1 CARNOSINE SYNTHASE 1 LEPOC|Ensembl=ENSLOCG00000000748.1|UniProtKB=W5LXH4 W5LXH4 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 regulation of chromosome segregation#GO:0051983;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of chromosome organization#GO:0033044;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;metaphase/anaphase transition of mitotic cell cycle#GO:0007091 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 Cell cycle#P00013>APC#P00481 LEPOC|Ensembl=ENSLOCG00000009429.1|UniProtKB=W5MT03 W5MT03 PTHR24240:SF178 OPSIN ADENOSINE RECEPTOR A3-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004173.1|UniProtKB=W5M9C5 W5M9C5 PTHR11576:SF13 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010683.1|UniProtKB=W5MXH7 W5MXH7 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011431.1|UniProtKB=W5N095 W5N095 PTHR10082:SF9 INTEGRIN BETA SUBUNIT INTEGRIN BETA-8 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000003058.1|UniProtKB=W5M5E1 W5M5E1 PTHR46052:SF4 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013880.1|UniProtKB=W5N907 W5N907 COX7B PTHR16716:SF0 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000959.1|UniProtKB=W5LY72 W5LY72 PTHR11311:SF7 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7B cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002515.1|UniProtKB=W5M3I9 W5M3I9 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007385.1|UniProtKB=W5MKQ1 W5MKQ1 PTHR47958:SF56 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000004038.1|UniProtKB=W5M8Y6 W5M8Y6 PTHR45847:SF6 FATTY ACID AMIDE HYDROLASE FATTY ACID AMIDE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular lipid catabolic process#GO:0044242;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010784.1|UniProtKB=W5MXV2 W5MXV2 PTHR22380:SF1 TESTIS-EXPRESSED PROTEIN 15 TESTIS-EXPRESSED PROTEIN 15 male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;regulation of double-strand break repair#GO:2000779;homologous chromosome segregation#GO:0045143;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;regulation of DNA metabolic process#GO:0051052;cell cycle process#GO:0022402;synaptonemal complex assembly#GO:0007130;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;chromosome organization involved in meiotic cell cycle#GO:0070192;regulation of cellular response to stress#GO:0080135;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;male meiotic nuclear division#GO:0007140;multicellular organismal reproductive process#GO:0048609;meiosis I#GO:0007127;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;multicellular organism reproduction#GO:0032504;homologous chromosome pairing at meiosis#GO:0007129;regulation of response to stress#GO:0080134;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;regulation of DNA recombination#GO:0000018;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004613.1|UniProtKB=W5MAW7 W5MAW7 PTHR11636:SF42 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010996.1|UniProtKB=W5MYP7 W5MYP7 PTHR10316:SF10 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013457.1|UniProtKB=W5N7I1 W5N7I1 PTHR45804:SF6 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-B13 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003355.1|UniProtKB=W5M6G5 W5M6G5 PTHR23257:SF974 SERINE-THREONINE PROTEIN KINASE RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006330.1|UniProtKB=W5MGY3 W5MGY3 PTHR46660:SF2 FAMILY NOT NAMED GLYCOSYLTRANSFERASE 1 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005409.1|UniProtKB=W5MDT0 W5MDT0 PTHR11140:SF0 PRE-MRNA SPLICING FACTOR PRP8 PRE-MRNA-PROCESSING-SPLICING FACTOR 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005208.1|UniProtKB=W5MD17 W5MD17 PTHR11599:SF42 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-7 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000003026.1|UniProtKB=W5M5A8 W5M5A8 PTHR10704:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 6 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017613.1|UniProtKB=W5NM59 W5NM59 PTHR24247:SF182 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M1 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000009379.1|UniProtKB=W5MST1 W5MST1 PTHR12322:SF76 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;regulation of DNA-templated transcription#GO:0006355;multicellular organism reproduction#GO:0032504;sex differentiation#GO:0007548;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000121.1|UniProtKB=W5LVH7 W5LVH7 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016166.1|UniProtKB=W5NH12 W5NH12 PTHR11662:SF432 SOLUTE CARRIER FAMILY 17 SIALIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003624.1|UniProtKB=W5M7E3 W5M7E3 PTHR24098:SF11 OUTER SEGMENT 5 INTRAFLAGELLAR TRANSPORT PROTEIN 80 HOMOLOG organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000007509.1|UniProtKB=W5ML75 W5ML75 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014965.1|UniProtKB=W5NCR5 W5NCR5 PTHR21083:SF0 TWISTER DYNEIN AXONEMAL ASSEMBLY FACTOR 6 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010957.1|UniProtKB=W5MYI2 W5MYI2 PTHR45732:SF13 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8B localization#GO:0051179;axo-dendritic transport#GO:0008088;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010783.1|UniProtKB=W5MXW1 W5MXW1 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010546.1|UniProtKB=W5MX18 W5MX18 PTHR12904:SF22 FAMILY NOT NAMED ZYG-11 FAMILY MEMBER B, CELL CYCLE REGULATOR intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000000094.1|UniProtKB=W5LVE7 W5LVE7 PTHR47230:SF1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of gene expression#GO:0010628;immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;positive regulation of type I interferon production#GO:0032481;activation of immune response#GO:0002253;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;pattern recognition receptor signaling pathway#GO:0002221;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRIF#P01344 LEPOC|Ensembl=ENSLOCG00000014899.1|UniProtKB=W5NCI9 W5NCI9 PTHR23043:SF25 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012314.1|UniProtKB=W5N3E1 W5N3E1 PTHR28572:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 103 COILED-COIL DOMAIN-CONTAINING PROTEIN 103 cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;inner dynein arm assembly#GO:0036159;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;epithelial cilium movement involved in extracellular fluid movement#GO:0003351;establishment of localization#GO:0051234;determination of left/right symmetry#GO:0007368;cytoskeleton organization#GO:0007010;pattern specification process#GO:0007389;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;left/right pattern formation#GO:0060972;multicellular organism development#GO:0007275;regionalization#GO:0003002;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement#GO:0003341;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031 LEPOC|Ensembl=ENSLOCG00000004877.1|UniProtKB=W5MBV7 W5MBV7 PTHR11849:SF312 ETS ETS VARIANT TRANSCRIPTION FACTOR 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000009077.1|UniProtKB=W5MRQ0 W5MRQ0 PTHR46105:SF23 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010772.1|UniProtKB=W5MXT6 W5MXT6 PTHR10454:SF234 CASPASE CASPASE 10, APOPTOSIS-RELATED CYSTEINE PEPTIDASE cysteine-type peptidase activity#GO:0008234;binding#GO:0005488;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;protein binding#GO:0005515;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013624.1|UniProtKB=W5N855 W5N855 PTHR23239:SF367 INTERMEDIATE FILAMENT KERATIN 15-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000013291.1|UniProtKB=W5N6Y8 W5N6Y8 PTHR22762:SF60 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE C hydrolase activity#GO:0016787;glucosidase activity#GO:0015926;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011151.1|UniProtKB=W5MZ89 W5MZ89 PTHR24067:SF280 UBIQUITIN-CONJUGATING ENZYME E2 SUMO-CONJUGATING ENZYME UBC9 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017673.1|UniProtKB=W5NMB9 W5NMB9 PTHR45822:SF4 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;positive regulation of protein secretion#GO:0050714;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;response to lipid#GO:0033993;regulation of biological process#GO:0050789;positive regulation of insulin secretion#GO:0032024;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;positive regulation of protein transport#GO:0051222;regulation of protein transport#GO:0051223;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;positive regulation of establishment of protein localization#GO:1904951;response to oxygen-containing compound#GO:1901700;response to fatty acid#GO:0070542;positive regulation of secretion#GO:0051047;positive regulation of transport#GO:0051050;cell communication#GO:0007154;regulation of hormone levels#GO:0010817;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;positive regulation of hormone secretion#GO:0046887;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of protein localization#GO:1903829;positive regulation of secretion by cell#GO:1903532;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015639.1|UniProtKB=W5NF43 W5NF43 PTHR11963:SF48 LEUCINE AMINOPEPTIDASE-RELATED DIPEPTIDASE B, ISOFORM A hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006993.1|UniProtKB=W5MJA4 W5MJA4 PTHR18966:SF100 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 4 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu4#P01015;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 LEPOC|Ensembl=ENSLOCG00000000108.1|UniProtKB=W5LVG0 W5LVG0 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009260.1|UniProtKB=W5MSD5 W5MSD5 PTHR15951:SF2 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of immune system process#GO:0002684;negative regulation of metabolic process#GO:0009892;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006106.1|UniProtKB=W5MG69 W5MG69 PTHR10381:SF11 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL serine-type endopeptidase activity#GO:0004252;ATP-dependent activity#GO:0140657;binding#GO:0005488;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule catabolic process#GO:0009057;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014697.1|UniProtKB=W5NBT6 W5NBT6 PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM LEPOC|Ensembl=ENSLOCG00000016739.1|UniProtKB=W5NJ78 W5NJ78 PTHR24393:SF165 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 555-LIKE DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004738.1|UniProtKB=W5MBB8 W5MBB8 PTHR34605:SF3 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN P CELL-TYPE AGGLUTINATION PROTEIN MAP4-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000009579.1|UniProtKB=W5MTK1 W5MTK1 NCBP1 PTHR12412:SF2 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007215.1|UniProtKB=W5MK22 W5MK22 PTHR31981:SF1 GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012299.1|UniProtKB=W5N3C6 W5N3C6 PTHR11909:SF18 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM DELTA non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000015819.1|UniProtKB=W5NFR8 W5NFR8 PTHR15146:SF0 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137B regulation of myeloid cell differentiation#GO:0045637;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;negative regulation of multicellular organismal process#GO:0051241;regulation of hemopoiesis#GO:1903706;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;regulation of tissue remodeling#GO:0034103;regulation of immune system process#GO:0002682;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of multicellular organismal process#GO:0051239;regulation of TORC1 signaling#GO:1903432;regulation of cell development#GO:0060284;regulation of autophagy#GO:0010506;regulation of cellular catabolic process#GO:0031329;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of bone resorption#GO:0045124;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of bone remodeling#GO:0046850;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015680.1|UniProtKB=W5NF92 W5NF92 PTHR11913:SF54 COFILIN-RELATED CFL1 PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;protein-containing complex disassembly#GO:0032984;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament depolymerization#GO:0030042 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000013999.1|UniProtKB=W5N9E7 W5N9E7 PTHR11644:SF26 CYTIDINE DEAMINASE CYTIDINE DEAMINASE cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;deaminase activity#GO:0019239;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009494.1|UniProtKB=W5MT96 W5MT96 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011613.1|UniProtKB=W5N0X2 W5N0X2 PTHR45641:SF19 TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870) NEPHROCYSTIN-3 LEPOC|Ensembl=ENSLOCG00000001922.1|UniProtKB=W5M1G4 W5M1G4 PTHR45134:SF5 OS08G0543275 PROTEIN OS08G0543275 PROTEIN LEPOC|Ensembl=ENSLOCG00000011317.1|UniProtKB=W5MZV4 W5MZV4 PTHR11636:SF68 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014883.1|UniProtKB=W5NCG9 W5NCG9 PTHR46221:SF1 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000014843.1|UniProtKB=W5NCB8 W5NCB8 PTHR18916:SF85 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008642.1|UniProtKB=W5MQ43 W5MQ43 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003753.1|UniProtKB=W5M7W5 W5M7W5 PTHR24067:SF280 UBIQUITIN-CONJUGATING ENZYME E2 SUMO-CONJUGATING ENZYME UBC9 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008389.1|UniProtKB=W5MP87 W5MP87 PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000014263.1|UniProtKB=W5NA98 W5NA98 PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882;Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883 LEPOC|Ensembl=ENSLOCG00000005562.1|UniProtKB=W5MEA7 W5MEA7 PTHR24221:SF242 ATP-BINDING CASSETTE SUB-FAMILY B ABC-TYPE OLIGOPEPTIDE TRANSPORTER ABCB9 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;amide transmembrane transporter activity#GO:0042887;peptide transmembrane transporter activity#GO:1904680;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006841.1|UniProtKB=W5MIR5 W5MIR5 PTHR11850:SF98 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 4 head development#GO:0060322;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;embryonic organ development#GO:0048568;cell differentiation#GO:0030154;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;visual system development#GO:0150063;sensory system development#GO:0048880;generation of neurons#GO:0048699;sensory organ development#GO:0007423 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010661.1|UniProtKB=W5MXF7 W5MXF7 PTHR10459:SF66 DNA LIGASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000011286.1|UniProtKB=W5MZR0 W5MZR0 DDIT4L PTHR12478:SF17 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4-LIKE PROTEIN regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006 LEPOC|Ensembl=ENSLOCG00000014557.1|UniProtKB=W5NBB3 W5NBB3 PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 hydrolase activity, acting on ester bonds#GO:0016788;DNA-directed DNA polymerase activity#GO:0003887;nuclease activity#GO:0004518;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;mitochondrial genome maintenance#GO:0000002;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;mitochondrial DNA metabolic process#GO:0032042;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;mitochondrion organization#GO:0007005;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000003365.1|UniProtKB=W5M6H5 W5M6H5 PTHR48071:SF5 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;extracellular region#GO:0005576;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000016037.1|UniProtKB=W5NGJ3 W5NGJ3 PTHR24073:SF963 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;vacuole organization#GO:0007033;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016420.1|UniProtKB=W5NI19 W5NI19 PTHR47048:SF1 PROTEIN SCAF11 PROTEIN SCAF11 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 LEPOC|Ensembl=ENSLOCG00000011163.1|UniProtKB=W5MZA6 W5MZA6 PTHR12329:SF16 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-folding chaperone binding#GO:0051087 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 LEPOC|Ensembl=ENSLOCG00000015702.1|UniProtKB=W5NFC5 W5NFC5 PTHR23152:SF4 2-OXOGLUTARATE DEHYDROGENASE 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 LEPOC|Ensembl=ENSLOCG00000011551.1|UniProtKB=W5N0N2 W5N0N2 TOMM7 PTHR46722:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG regulation of biological process#GO:0050789;positive regulation of establishment of protein localization#GO:1904951;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;positive regulation of protein localization#GO:1903829;regulation of cellular localization#GO:0060341;positive regulation of biological process#GO:0048518;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;positive regulation of cellular process#GO:0048522 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016612.1|UniProtKB=W5NIR8 W5NIR8 PTHR45833:SF1 METHIONINE SYNTHASE METHIONINE SYNTHASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953 LEPOC|Ensembl=ENSLOCG00000013067.1|UniProtKB=W5N635 W5N635 PTHR24230:SF13 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011424.1|UniProtKB=W5N093 W5N093 PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000005173.1|UniProtKB=W5MCX1 W5MCX1 PTHR14572:SF0 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR LEPOC|Ensembl=ENSLOCG00000007303.1|UniProtKB=W5MKD5 W5MKD5 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017090.1|UniProtKB=W5NKG5 W5NKG5 PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE_SERINE-RICH PROTEIN PNISR LEPOC|Ensembl=ENSLOCG00000001068.1|UniProtKB=W5LYL2 W5LYL2 PTHR13140:SF663 MYOSIN UNCONVENTIONAL MYOSIN-IF microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;transport#GO:0006810;endocytosis#GO:0006897;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000012333.1|UniProtKB=W5N3H0 W5N3H0 PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001485.1|UniProtKB=W5M002 W5M002 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004118.1|UniProtKB=W5M965 W5M965 PTHR24088:SF0 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005457.1|UniProtKB=W5MDY7 W5MDY7 PTHR24351:SF43 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;CCKR signaling map#P06959>RSK1/2#P07153;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000005339.1|UniProtKB=W5MDH4 W5MDH4 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000006701.1|UniProtKB=W5MI85 W5MI85 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001783.1|UniProtKB=W5M175 W5M175 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;transport#GO:0006810;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;import into cell#GO:0098657;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000830.1|UniProtKB=W5LXR7 W5LXR7 PTHR11422:SF5 T-CELL SURFACE GLYCOPROTEIN CD4 DIVERSE IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1.1 ISOFORM X1-RELATED binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;MHC protein binding#GO:0042287;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;lymphocyte activation#GO:0046649;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000009.1|UniProtKB=W5LV53 W5LV53 PTHR35084:SF1 TCF3 FUSION PARTNER TCF3 FUSION PARTNER nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010060.1|UniProtKB=W5MV99 W5MV99 PTHR44269:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010743.1|UniProtKB=W5MXQ6 W5MXQ6 PTHR48033:SF3 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001935.1|UniProtKB=W5M1H8 W5M1H8 PTHR12935:SF13 GAMMA-GLUTAMYLCYCLOTRANSFERASE GAMMA-GLUTAMYLCYCLOTRANSFERASE lyase activity#GO:0016829;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000008802.1|UniProtKB=W5MQQ5 W5MQQ5 PTHR13924:SF11 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 2 head development#GO:0060322;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;animal organ development#GO:0048513;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;brain development#GO:0007420;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;forebrain development#GO:0030900;system development#GO:0048731;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000602.1|UniProtKB=W5LX10 W5LX10 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017859.1|UniProtKB=W5NMV3 W5NMV3 PTHR36542:SF6 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREP cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013093.1|UniProtKB=W5N676 W5N676 PTHR10625:SF28 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 5 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004485.1|UniProtKB=W5MAF2 W5MAF2 PTHR46252:SF2 BRORIN FAMILY MEMBER VON WILLEBRAND FACTOR C DOMAIN-CONTAINING PROTEIN 2-LIKE regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;monoatomic ion channel complex#GO:0034702;extracellular region#GO:0005576;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010007.1|UniProtKB=W5MV36 W5MV36 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009240.1|UniProtKB=W5MSB9 W5MSB9 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007694.1|UniProtKB=W5MLV3 W5MLV3 PTHR10514:SF24 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME 2 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000018288.1|UniProtKB=W5NMA8 W5NMA8 PTHR14758:SF3 AGAP005440-PA PROTEIN FAM110D LEPOC|Ensembl=ENSLOCG00000001135.1|UniProtKB=W5LYS8 W5LYS8 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004787.1|UniProtKB=W5MBI5 W5MBI5 PTHR10332:SF10 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014205.1|UniProtKB=W5NA38 W5NA38 PTHR15572:SF1 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000001244.1|UniProtKB=W5LZ52 W5LZ52 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000006390.1|UniProtKB=W5MH55 W5MH55 ARHGAP40 PTHR14963:SF4 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 40 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of signaling#GO:0023051;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of supramolecular fiber organization#GO:1902903;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004409.1|UniProtKB=W5MA58 W5MA58 PTHR12623:SF6 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 LEPOC|Ensembl=ENSLOCG00000007277.1|UniProtKB=W5MKA0 W5MKA0 PTHR12002:SF6 CLAUDIN CLAUDIN-11 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000004340.1|UniProtKB=W5M9Y7 W5M9Y7 PTHR13817:SF55 TITIN PROTEIN SIDEKICK-1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003761.1|UniProtKB=W5M7X9 W5M7X9 PTHR46315:SF1 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;polyamine biosynthetic process#GO:0006596;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000011542.1|UniProtKB=W5N0M7 W5N0M7 PTHR23113:SF26 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017929.1|UniProtKB=W5NN23 W5NN23 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 53 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000011887.1|UniProtKB=W5N1W4 W5N1W4 PTHR46062:SF3 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000015022.1|UniProtKB=W5NCY7 W5NCY7 PTHR10110:SF89 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 2 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007056.1|UniProtKB=W5MJJ2 W5MJJ2 PTHR46108:SF1 BLUE CHEESE WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3 process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 LEPOC|Ensembl=ENSLOCG00000014971.1|UniProtKB=W5NCS5 W5NCS5 PTHR10937:SF12 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;cellular aromatic compound metabolic process#GO:0006725;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;UDP-N-acetylglucosamine metabolic process#GO:0006047;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;protein N-linked glycosylation#GO:0006487;amino sugar metabolic process#GO:0006040;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 LEPOC|Ensembl=ENSLOCG00000013017.1|UniProtKB=W5N5X7 W5N5X7 PTHR17613:SF11 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 1 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000008348.1|UniProtKB=W5MP36 W5MP36 PTHR22100:SF13 WINGS APART-LIKE PROTEIN HOMOLOG WINGS APART-LIKE PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000010436.1|UniProtKB=W5MWN6 W5MWN6 PTHR31626:SF1 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;stress fiber assembly#GO:0043149;regulation of anatomical structure morphogenesis#GO:0022603;contractile actin filament bundle assembly#GO:0030038;actin filament bundle assembly#GO:0051017;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cell shape#GO:0008360;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000131.1|UniProtKB=W5LVI5 W5LVI5 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 LEPOC|Ensembl=ENSLOCG00000000623.1|UniProtKB=W5LX32 W5LX32 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017367.1|UniProtKB=W5NLG3 W5NLG3 PTHR15283:SF2 GREMLIN 1 GREMLIN-2 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;animal organ development#GO:0048513;developmental process#GO:0032502;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013055.1|UniProtKB=W5N626 W5N626 PTHR48013:SF12 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p38 MAPK pathway#P05918>MKK6#P06032;Oxidative stress response#P00046>MKK3/6#P01121;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;FGF signaling pathway#P00021>MKK3,6#P00625;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Ras Pathway#P04393>MKK3/6#P04568;CCKR signaling map#P06959>MAP2K6#P07233 LEPOC|Ensembl=ENSLOCG00000005727.1|UniProtKB=W5MEV8 W5MEV8 PTHR13376:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;motile cilium#GO:0031514;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000003404.1|UniProtKB=W5M6M9 W5M6M9 PTHR22935:SF95 PENICILLIN-BINDING PROTEIN BETA-LACTAMASE-LIKE 1-RELATED LEPOC|Ensembl=ENSLOCG00000014220.1|UniProtKB=W5NA54 W5NA54 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000010542.1|UniProtKB=W5MX14 W5MX14 PTHR11089:SF11 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011256.1|UniProtKB=W5MZN2 W5MZN2 KLHL28 PTHR24412:SF441 KELCH PROTEIN KELCH-LIKE PROTEIN 28 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011908.1|UniProtKB=W5N1Y7 W5N1Y7 PTHR22603:SF94 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000011534.1|UniProtKB=W5N0L7 W5N0L7 PTHR45899:SF4 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009950.1|UniProtKB=W5MUV8 W5MUV8 PTHR14731:SF0 BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005881.1|UniProtKB=W5MFF0 W5MFF0 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 LEPOC|Ensembl=ENSLOCG00000003635.1|UniProtKB=W5M7F0 W5M7F0 PTHR14057:SF10 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015058.1|UniProtKB=W5ND27 W5ND27 PTHR19134:SF285 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018165.1|UniProtKB=W5NNQ7 W5NNQ7 PTHR11829:SF68 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN C1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000000768.1|UniProtKB=W5LXJ8 W5LXJ8 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007070.1|UniProtKB=W5MJK0 W5MJK0 PTHR23428:SF344 HISTONE H2B HISTONE H2B TYPE 2-K1 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009424.1|UniProtKB=W5MT06 W5MT06 PTHR46049:SF4 AGAP003327-PA UNCONVENTIONAL MYOSIN-X neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon extension#GO:0048675;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 axonal growth cone#GO:0044295;neuron projection#GO:0043005;distal axon#GO:0150034;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;growth cone#GO:0030426;site of polarized growth#GO:0030427;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000017235.1|UniProtKB=W5NL08 W5NL08 PTHR24300:SF302 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014414.1|UniProtKB=W5NAT4 W5NAT4 PTHR17604:SF4 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 VESTIGIAL-LIKE 4 LIKE protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012073.1|UniProtKB=W5N2J4 W5N2J4 PTHR11860:SF87 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003935.1|UniProtKB=W5M8K5 W5M8K5 PES1 PTHR12221:SF6 PESCADILLO - RELATED PESCADILLO HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009946.1|UniProtKB=W5MUV3 W5MUV3 OTOP1 PTHR21522:SF19 PROTON CHANNEL OTOP PROTON CHANNEL OTOP1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 sensory organ morphogenesis#GO:0090596;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;animal organ development#GO:0048513;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ear development#GO:0043583;localization#GO:0051179;embryonic organ development#GO:0048568;embryo development#GO:0009790;inner ear development#GO:0048839;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;inner ear morphogenesis#GO:0042472;animal organ morphogenesis#GO:0009887;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;monoatomic ion transport#GO:0006811;embryonic morphogenesis#GO:0048598;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001686.1|UniProtKB=W5M0Q2 W5M0Q2 PTHR14198:SF18 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002161.1|UniProtKB=W5M2D4 W5M2D4 PTHR13315:SF0 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE 1 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000001457.1|UniProtKB=W5LZV3 W5LZV3 PTHR45632:SF13 LD33804P KELCH-LIKE PROTEIN 26 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004870.1|UniProtKB=W5MBU8 W5MBU8 PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009187.1|UniProtKB=W5MS64 W5MS64 PTHR19443:SF10 HEXOKINASE HEXOKINASE-1 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;intracellular chemical homeostasis#GO:0055082;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;organophosphate catabolic process#GO:0046434;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate phosphorylation#GO:0046835;organonitrogen compound metabolic process#GO:1901564;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;intracellular glucose homeostasis#GO:0001678;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 LEPOC|Ensembl=ENSLOCG00000004692.1|UniProtKB=W5MB60 W5MB60 PTHR10985:SF78 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;signaling#GO:0023052;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000007307.1|UniProtKB=W5MKE5 W5MKE5 PTHR45711:SF2 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 4 voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;Golgi apparatus#GO:0005794;cell junction#GO:0030054;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006831.1|UniProtKB=W5MIQ2 W5MIQ2 PTHR10972:SF76 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 6 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 envelope#GO:0031975;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005886.1|UniProtKB=W5MFF1 W5MFF1 PTHR32193:SF3 REGULATOR OF CELL CYCLE RGCC REGULATOR OF CELL CYCLE RGCC LEPOC|Ensembl=ENSLOCG00000006952.1|UniProtKB=W5MJ51 W5MJ51 PTHR24343:SF539 SERINE/THREONINE KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007482.1|UniProtKB=W5ML27 W5ML27 DISP3 PTHR46687:SF1 PROTEIN DISPATCHED HOMOLOG 3 PROTEIN DISPATCHED HOMOLOG 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015614.1|UniProtKB=W5NF12 W5NF12 MAL PTHR22776:SF12 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MYELIN AND LYMPHOCYTE PROTEIN structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004268.1|UniProtKB=W5M9P1 W5M9P1 AMZ1 PTHR32205:SF4 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-1 LEPOC|Ensembl=ENSLOCG00000006637.1|UniProtKB=W5MI11 W5MI11 PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010024.1|UniProtKB=W5MV43 W5MV43 PTHR11860:SF118 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013549.1|UniProtKB=W5N7V1 W5N7V1 PTHR11353:SF94 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000015920.1|UniProtKB=W5NG42 W5NG42 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000010881.1|UniProtKB=W5MY89 W5MY89 PTHR19376:SF11 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000014384.1|UniProtKB=W5NAQ6 W5NAQ6 PTHR23257:SF727 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012244.1|UniProtKB=W5N348 W5N348 PTHR19308:SF39 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN PHOSPHATIDYLCHOLINE TRANSFER PROTEIN LEPOC|Ensembl=ENSLOCG00000010476.1|UniProtKB=W5MWT6 W5MWT6 FAM3D PTHR14592:SF11 UNCHARACTERIZED FAM3 PROTEIN FAM3A extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 LEPOC|Ensembl=ENSLOCG00000016574.1|UniProtKB=W5NIL5 W5NIL5 PTHR24240:SF197 OPSIN OPSIN-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013034.1|UniProtKB=W5N5Z7 W5N5Z7 PTHR11588:SF100 TUBULIN TUBULIN BETA-2A CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 LEPOC|Ensembl=ENSLOCG00000013676.1|UniProtKB=W5N8A5 W5N8A5 MLLT6 PTHR13793:SF90 PHD FINGER PROTEINS PROTEIN AF-17 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011207.1|UniProtKB=W5MZG3 W5MZG3 PTHR46805:SF2 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1-A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000008083.1|UniProtKB=W5MN59 W5MN59 ISG20L2 PTHR12801:SF78 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED 20 KDA EXONUCLEASE-LIKE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000017980.1|UniProtKB=W5NN72 W5NN72 NPY3R PTHR24241:SF145 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010867.1|UniProtKB=W5MY80 W5MY80 PTHR24416:SF564 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005320.1|UniProtKB=W5MDF5 W5MDF5 PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 LEPOC|Ensembl=ENSLOCG00000017466.1|UniProtKB=W5NLR2 W5NLR2 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007008.1|UniProtKB=W5MJC7 W5MJC7 PTHR24240:SF189 OPSIN TELEOST MULTIPLE TISSUE OPSIN A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015781.1|UniProtKB=W5NFM5 W5NFM5 PTHR38537:SF12 JITTERBUG, ISOFORM N FILAMIN-C LEPOC|Ensembl=ENSLOCG00000004881.1|UniProtKB=W5MBX7 W5MBX7 PTHR21394:SF0 MAU2 CHROMATID COHESION FACTOR HOMOLOG MAU2 CHROMATID COHESION FACTOR HOMOLOG nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007716.1|UniProtKB=W5MLW2 W5MLW2 PTHR13363:SF6 RING FINGER AND SRY DOMAIN-CONTAINING RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006441.1|UniProtKB=W5MHC2 W5MHC2 PTHR24068:SF36 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000004049.1|UniProtKB=W5M8X9 W5M8X9 PTHR44656:SF6 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12-LIKE dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015859.1|UniProtKB=W5NFW7 W5NFW7 PTHR11769:SF7 HYALURONIDASE HYALURONIDASE-4 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013677.1|UniProtKB=W5N8D1 W5N8D1 PTHR10857:SF112 COPINE COPINE-9 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000003451.1|UniProtKB=W5M6U5 W5M6U5 PTHR11596:SF90 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000018010.1|UniProtKB=W5NNA2 W5NNA2 HTR1B PTHR24247:SF16 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 LEPOC|Ensembl=ENSLOCG00000006562.1|UniProtKB=W5MHR8 W5MHR8 PTHR48036:SF6 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA BINDING MOTIF PROTEIN 39B ISOFORM X1-RELATED ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000018223.1|UniProtKB=W5NNW5 W5NNW5 PTHR24393:SF151 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011500.1|UniProtKB=W5N0H4 W5N0H4 PTHR11329:SF0 LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 LEUKOCYTE CELL-DERIVED CHEMOTAXIN-2 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000017277.1|UniProtKB=W5NL61 W5NL61 PTHR12247:SF72 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005566.1|UniProtKB=W5MEB3 W5MEB3 PTHR12316:SF28 NINJURIN-RELATED NINJURIN-2-LIKE cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016583.1|UniProtKB=W5NIM3 W5NIM3 PTHR45678:SF11 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;acidic amino acid transmembrane transporter activity#GO:0015172 cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;respiratory electron transport chain#GO:0022904;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016977.1|UniProtKB=W5NK26 W5NK26 HDAC2 PTHR10625:SF46 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 2 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000016147.1|UniProtKB=W5NGY8 W5NGY8 PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 aldolase#PC00044;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000018050.1|UniProtKB=W5NNE2 W5NNE2 ACTL7A PTHR11937:SF574 ACTIN ACTIN-LIKE PROTEIN ARP9 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000012551.1|UniProtKB=W5N499 W5N499 PTHR43908:SF2 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 18 heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;chaperone cofactor-dependent protein refolding#GO:0051085;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001554.1|UniProtKB=W5M084 W5M084 PTHR14131:SF7 ANOSMIN ANOSMIN 1B cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000000652.1|UniProtKB=W5LX61 W5LX61 PTHR46708:SF7 TENASCIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;cell-substrate junction assembly#GO:0007044;system development#GO:0048731;cell-matrix adhesion#GO:0007160;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000003122.1|UniProtKB=W5M5M0 W5M5M0 PTHR12822:SF4 PROTEIN YIPF PROTEIN YIPF1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005607.1|UniProtKB=W5MEG0 W5MEG0 PTHR24330:SF8 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 1 HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003578.1|UniProtKB=W5M785 W5M785 PTHR46823:SF2 CALCINEURIN B HOMOLOGOUS PROTEIN 3 CALCINEURIN B HOMOLOGOUS PROTEIN 3 cation binding#GO:0043169;phosphatase regulator activity#GO:0019208;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of myeloid cell differentiation#GO:0045637;cellular localization#GO:0051641;regulation of sodium ion transport#GO:0002028;macromolecule localization#GO:0033036;regulation of metal ion transport#GO:0010959;positive regulation of molecular function#GO:0044093;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of hemopoiesis#GO:1903706;regulation of molecular function#GO:0065009;regulation of immune system process#GO:0002682;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of cell adhesion#GO:0030155;regulation of transporter activity#GO:0032409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;protein localization to plasma membrane#GO:0072659;regulation of monoatomic ion transmembrane transport#GO:0034765;localization within membrane#GO:0051668;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;protein localization to membrane#GO:0072657;positive regulation of immune system process#GO:0002684;positive regulation of transport#GO:0051050;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;positive regulation of transporter activity#GO:0032411;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell adhesion mediated by integrin#GO:0033628;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008437.1|UniProtKB=W5MPE9 W5MPE9 PTHR11309:SF45 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 LEPOC|Ensembl=ENSLOCG00000008657.1|UniProtKB=W5MQ76 W5MQ76 PTHR12601:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle localization#GO:0051640;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014515.1|UniProtKB=W5NB54 W5NB54 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE_DNA LYASE DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005759.1|UniProtKB=W5MEZ4 W5MEZ4 PTHR10155:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;response to insulin#GO:0032868;phosphatidylinositol biosynthetic process#GO:0006661;response to peptide hormone#GO:0043434;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;glycerophospholipid biosynthetic process#GO:0046474;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p85#P01202;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 LEPOC|Ensembl=ENSLOCG00000003322.1|UniProtKB=W5M6B7 W5M6B7 SBK1 PTHR24359:SF0 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013698.1|UniProtKB=W5N8D2 W5N8D2 PTHR11599:SF46 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-6 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001633.1|UniProtKB=W5M0H9 W5M0H9 PTHR11804:SF79 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000411.1|UniProtKB=W5LWE2 W5LWE2 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006378.1|UniProtKB=W5MH42 W5MH42 PTHR21052:SF0 SPERMATOGENESIS ASSOCIATED 11-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000016754.1|UniProtKB=W5NJA0 W5NJA0 PTHR47437:SF2 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 2 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;JNK cascade#GO:0007254;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006966.1|UniProtKB=W5MJ71 W5MJ71 PTHR24286:SF101 CYTOCHROME P450 26 CYTOCHROME P450 26A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006961.1|UniProtKB=W5MJ57 W5MJ57 PTHR12219:SF8 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016871.1|UniProtKB=W5NJP6 W5NJP6 PTHR45636:SF15 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015515.1|UniProtKB=W5NEN7 W5NEN7 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000008594.1|UniProtKB=W5MPZ0 W5MPZ0 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009156.1|UniProtKB=W5MS22 W5MS22 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;DNA-templated transcription#GO:0006351;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000017861.1|UniProtKB=W5NMV5 W5NMV5 H2AX PTHR23430:SF410 HISTONE H2A HISTONE H2A nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000282.1|UniProtKB=W5LW00 W5LW00 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000017249.1|UniProtKB=W5NL26 W5NL26 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013388.1|UniProtKB=W5N793 W5N793 PTHR10438:SF463 THIOREDOXIN THIOREDOXIN oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 LEPOC|Ensembl=ENSLOCG00000018235.1|UniProtKB=W5NNX7 W5NNX7 ZNF518A PTHR24392:SF39 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518A C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003241.1|UniProtKB=W5M621 W5M621 PTHR11066:SF34 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 8 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;lipid catabolic process#GO:0016042;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000011595.1|UniProtKB=W5N0T8 W5N0T8 PTHR11988:SF24 THYROTROPH EMBRYONIC FACTOR RELATED THYROTROPH EMBRYONIC FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000013051.1|UniProtKB=W5N627 W5N627 PTHR23169:SF26 ENVOPLAKIN DESMOPLAKIN animal organ development#GO:0048513;developmental process#GO:0032502;cell-cell adhesion#GO:0098609;wound healing#GO:0042060;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;skin development#GO:0043588;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intercalated disc#GO:0014704;cell-cell contact zone#GO:0044291;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000003231.1|UniProtKB=W5M607 W5M607 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010297.1|UniProtKB=W5MW53 W5MW53 PTHR24211:SF18 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006467.1|UniProtKB=W5MHH5 W5MHH5 PTHR13408:SF1 DNA-DIRECTED RNA POLYMERASE III ZGC:171971 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000005672.1|UniProtKB=W5MEP0 W5MEP0 PTHR32455:SF1 SPERM ACROSOME-ASSOCIATED PROTEIN 9 SPERM ACROSOME-ASSOCIATED PROTEIN 9 acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;ciliary base#GO:0097546;secretory granule#GO:0030141;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;motile cilium#GO:0031514;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cilium#GO:0005929;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000014133.1|UniProtKB=W5N9V0 W5N9V0 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 LEPOC|Ensembl=ENSLOCG00000016445.1|UniProtKB=W5NI54 W5NI54 PTHR16160:SF12 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 LEPOC|Ensembl=ENSLOCG00000008885.1|UniProtKB=W5MR06 W5MR06 PTHR14543:SF1 PROTRUDIN PROTRUDIN protein binding#GO:0005515;binding#GO:0005488 protein localization to plasma membrane#GO:0072659;cellular component assembly#GO:0022607;localization within membrane#GO:0051668;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;endoplasmic reticulum tubular network organization#GO:0071786;establishment of localization#GO:0051234;organelle organization#GO:0006996 cytoplasm#GO:0005737;endoplasmic reticulum tubular network#GO:0071782;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017575.1|UniProtKB=W5NM21 W5NM21 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015556.1|UniProtKB=W5NEU5 W5NEU5 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009827.1|UniProtKB=W5MUF4 W5MUF4 PTHR11803:SF39 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA 2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;catalytic activity#GO:0003824 organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013143.1|UniProtKB=W5N6D3 W5N6D3 PTHR10160:SF30 NAD(P) TRANSHYDROGENASE PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017033.1|UniProtKB=W5NK95 W5NK95 PTHR42765:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013107.1|UniProtKB=W5N686 W5N686 PTHR21522:SF35 PROTON CHANNEL OTOP PROTON CHANNEL OTOP2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006089.1|UniProtKB=W5MG75 W5MG75 PTHR46513:SF37 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LDL RECEPTOR RELATED PROTEIN 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018230.1|UniProtKB=W5NNX2 W5NNX2 PTHR24248:SF123 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 LEPOC|Ensembl=ENSLOCG00000003939.1|UniProtKB=W5M8J7 W5M8J7 PTHR45762:SF2 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000858.1|UniProtKB=W5LXV5 W5LXV5 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248 oxidase#PC00175;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000016052.1|UniProtKB=W5NGL6 W5NGL6 PTHR12358:SF25 SPHINGOSINE KINASE CERAMIDE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012814.1|UniProtKB=W5N557 W5N557 PTHR13080:SF13 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;oxidative phosphorylation#GO:0006119;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014250.1|UniProtKB=W5NA87 W5NA87 PTHR11040:SF120 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015759.1|UniProtKB=W5NFJ6 W5NFJ6 PTHR10362:SF7 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000008270.1|UniProtKB=W5MNS8 W5MNS8 PTHR46749:SF1 COMPLEX III ASSEMBLY FACTOR LYRM7 COMPLEX III ASSEMBLY FACTOR LYRM7 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007925.1|UniProtKB=W5MML2 W5MML2 PTHR31592:SF1 TRANSMEMBRANE PROTEIN 192 TRANSMEMBRANE PROTEIN 192 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000015627.1|UniProtKB=W5NF28 W5NF28 PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014495.1|UniProtKB=W5NB40 W5NB40 PTHR15076:SF12 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000003214.1|UniProtKB=W5M672 W5M672 PTHR16166:SF141 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein localization to Golgi apparatus#GO:0034067;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;maintenance of location#GO:0051235;organelle organization#GO:0006996;maintenance of location in cell#GO:0051651;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;intracellular transport#GO:0046907 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003190.1|UniProtKB=W5M5W4 W5M5W4 PTHR24322:SF483 PKSB SHORT-CHAIN DEHYDROGENASE_REDUCTASE 3 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011044.1|UniProtKB=W5MYU7 W5MYU7 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000018283.1|UniProtKB=W5NP25 W5NP25 PTHR22750:SF19 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014383.1|UniProtKB=W5NAQ1 W5NAQ1 PTHR11472:SF1 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;DNA-templated transcription#GO:0006351;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of DNA recombination#GO:0000018;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005926.1|UniProtKB=W5MFJ5 W5MFJ5 PTHR10036:SF13 CD59 GLYCOPROTEIN CD59 MOLECULE (CD59 BLOOD GROUP) LEPOC|Ensembl=ENSLOCG00000004724.1|UniProtKB=W5MBA4 W5MBA4 PTHR10985:SF150 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT 5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000015382.1|UniProtKB=W5NE80 W5NE80 PTHR46007:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001435.1|UniProtKB=W5LZS8 W5LZS8 C11orf1 PTHR34524:SF1 CALCYPHOSIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 68 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000005073.1|UniProtKB=W5MCK6 W5MCK6 PTHR12394:SF4 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-1 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000016333.1|UniProtKB=W5NHQ7 W5NHQ7 PTHR18919:SF153 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000003266.1|UniProtKB=W5M658 W5M658 RIC3 PTHR21723:SF3 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 PROTEIN RIC-3 localization#GO:0051179;regulation of biological process#GO:0050789;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;chemical synaptic transmission#GO:0007268;macromolecule localization#GO:0033036;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267;protein localization#GO:0008104 somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007135.1|UniProtKB=W5MJS5 W5MJS5 PTHR24073:SF839 DRAB5-RELATED RAS-RELATED PROTEIN RAB-38 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017977.1|UniProtKB=W5NN69 W5NN69 PTHR19268:SF4 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 173-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014648.1|UniProtKB=W5NBL7 W5NBL7 PTHR23426:SF73 FERREDOXIN/ADRENODOXIN FERREDOXIN 1B cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017437.1|UniProtKB=W5NLN3 W5NLN3 PTHR11984:SF50 CONNEXIN GAP JUNCTION DELTA-2 PROTEIN-LIKE wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000013758.1|UniProtKB=W5N8L4 W5N8L4 PTHR43272:SF28 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 1 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008646.1|UniProtKB=W5MQ49 W5MQ49 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 LEPOC|Ensembl=ENSLOCG00000000304.1|UniProtKB=W5LW24 W5LW24 PTHR47614:SF2 GLYCOPHORIN-C GLYCOPHORIN-C cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cortical cytoskeleton#GO:0030863;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009724.1|UniProtKB=W5MU18 W5MU18 PTHR31844:SF2 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017716.1|UniProtKB=W5NMG2 W5NMG2 PTHR16277:SF6 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000000918.1|UniProtKB=W5LY17 W5LY17 PTHR10339:SF25 ADP-RIBOSYLTRANSFERASE SECRETED EXOENZYME S transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013124.1|UniProtKB=W5N6B2 W5N6B2 PTHR10822:SF24 GLYPICAN GLYPICAN-2 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of protein localization to membrane#GO:1905475;regulation of localization#GO:0032879;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell migration#GO:0016477;signaling#GO:0023052;regulation of protein localization#GO:0032880 cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015228.1|UniProtKB=W5NDN0 W5NDN0 PTHR24089:SF246 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 43 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013947.1|UniProtKB=W5N986 W5N986 PTHR47130:SF6 SI:DKEY-19B23.11-RELATED EGG ENVELOPE GLYCOPROTEIN-LIKE PRECURSOR LEPOC|Ensembl=ENSLOCG00000013693.1|UniProtKB=W5N8C2 W5N8C2 PTHR12345:SF12 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2 amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 LEPOC|Ensembl=ENSLOCG00000004451.1|UniProtKB=W5MAB7 W5MAB7 PTHR19229:SF29 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA GLUCOSYLCERAMIDE TRANSPORTER ABCA12 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;binding#GO:0005488;protein binding#GO:0005515;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;signaling receptor binding#GO:0005102;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014641.1|UniProtKB=W5NBL2 W5NBL2 PTHR10454:SF155 CASPASE CASPASE-14-LIKE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015174.1|UniProtKB=W5NDG2 W5NDG2 PTHR23049:SF39 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, ATRIAL ISOFORM cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 blood circulation#GO:0008015;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;system process#GO:0003008;developmental process#GO:0032502;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;circulatory system process#GO:0003013;tissue development#GO:0009888;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;myosin complex#GO:0016459;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005103.1|UniProtKB=W5MCN7 W5MCN7 PTHR22776:SF45 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CHEMOKINE-LIKE FACTOR cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016973.1|UniProtKB=W5NK23 W5NK23 PTHR24418:SF468 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FRK protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Parkinson disease#P00049>Src kinase#P01230;Cadherin signaling pathway#P00012>Fyn#P00464;Integrin signalling pathway#P00034>Src#P00940;B cell activation#P00010>Blk#P00390;Parkinson disease#P00049>Fyn kinase#P01235 LEPOC|Ensembl=ENSLOCG00000011936.1|UniProtKB=W5N2L6 W5N2L6 MYH2 PTHR45615:SF6 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-3 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000009244.1|UniProtKB=W5MSC0 W5MSC0 PTHR11905:SF19 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 19 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;membrane protein ectodomain proteolysis#GO:0006509;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010416.1|UniProtKB=W5MWM8 W5MWM8 SUCLA2 PTHR11815:SF1 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;acyl-CoA metabolic process#GO:0006637;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006464.1|UniProtKB=W5MHF2 W5MHF2 PTHR22917:SF9 HEMOPEXIN DOMAIN-CONTAINING PROTEIN HEMOPEXIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000002226.1|UniProtKB=W5M2I7 W5M2I7 PTHR14817:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000008206.1|UniProtKB=W5MNK2 W5MNK2 PTHR46784:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of natural killer cell mediated immunity#GO:0002715;regulation of response to external stimulus#GO:0032101;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of response to biotic stimulus#GO:0002831;regulation of biological process#GO:0050789;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of immune effector process#GO:0002697;regulation of cellular process#GO:0050794;regulation of cell killing#GO:0031341;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune system process#GO:0002682 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004427.1|UniProtKB=W5MA78 W5MA78 PTHR11373:SF4 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;nucleoside triphosphate catabolic process#GO:0009143;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001283.1|UniProtKB=W5LZ93 W5LZ93 PTHR11539:SF0 VDJ RECOMBINATION ACTIVATING PROTEIN 1 RAG1 V(D)J RECOMBINATION-ACTIVATING PROTEIN 1 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000010379.1|UniProtKB=W5MWG1 W5MWG1 PTHR45638:SF8 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-3 monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;ligand-gated monoatomic cation channel activity#GO:0099094;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 9+0 non-motile cilium#GO:0097731;membrane protein complex#GO:0098796;non-motile cilium#GO:0097730;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000005398.1|UniProtKB=W5MDR5 W5MDR5 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000008076.1|UniProtKB=W5MN49 W5MN49 PTHR26451:SF889 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 2A12-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008098.1|UniProtKB=W5MN73 W5MN73 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007615.1|UniProtKB=W5MLI3 W5MLI3 PTHR10747:SF4 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000009544.1|UniProtKB=W5MTF4 W5MTF4 PTHR46005:SF2 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 5 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of anatomical structure size#GO:0090066;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;regulation of cellular component size#GO:0032535;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of axonogenesis#GO:0050770;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000009385.1|UniProtKB=W5MSV3 W5MSV3 PTHR14338:SF1 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 1 protein binding#GO:0005515;SH3 domain binding#GO:0017124;binding#GO:0005488 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006233.1|UniProtKB=W5MGM1 W5MGM1 PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013961.1|UniProtKB=W5N9A1 W5N9A1 PTHR15151:SF20 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 12 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003763.1|UniProtKB=W5M7Y4 W5M7Y4 PTHR15564:SF7 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 1 response to organic substance#GO:0010033;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of cell cycle#GO:0045786;response to lipid#GO:0033993;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;dendrite#GO:0030425;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000873.1|UniProtKB=W5LXW3 W5LXW3 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000982.1|UniProtKB=W5LY96 W5LY96 PTHR42912:SF93 METHYLTRANSFERASE N6-ADENOSINE-METHYLTRANSFERASE TMT1A methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000006817.1|UniProtKB=W5MIR6 W5MIR6 PTHR46877:SF8 EPH RECEPTOR A5 RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001717.1|UniProtKB=W5M0T7 W5M0T7 PTHR10104:SF17 STATHMIN STATHMIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014677.1|UniProtKB=W5NBR8 W5NBR8 PTHR11616:SF237 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001796.1|UniProtKB=W5M123 W5M123 PTHR11849:SF306 ETS ETS TRANSLOCATION VARIANT 3-LIKE PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000010670.1|UniProtKB=W5MXF9 W5MXF9 PTHR12062:SF11 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN MGAT4E acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007969.1|UniProtKB=W5MMR8 W5MMR8 PTHR14273:SF0 LYR MOTIF-CONTAINING PROTEIN 1 LYR MOTIF-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007963.1|UniProtKB=W5MMR1 W5MMR1 PTHR45944:SF3 SCHNURRI, ISOFORM F ZINC FINGER PROTEIN 40 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017531.1|UniProtKB=W5NLX7 W5NLX7 PTHR47097:SF1 HEAT SHOCK PROTEIN BETA-3 HEAT SHOCK PROTEIN BETA-3 cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017003.1|UniProtKB=W5NK70 W5NK70 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA metabolism protein#PC00009;primase#PC00189 DNA replication#P00017>Primase#P00528 LEPOC|Ensembl=ENSLOCG00000007243.1|UniProtKB=W5MK73 W5MK73 PTHR16059:SF13 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008172.1|UniProtKB=W5MNG3 W5MNG3 DTX1 PTHR12622:SF7 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006061.1|UniProtKB=W5MG09 W5MG09 PTHR12822:SF3 PROTEIN YIPF PROTEIN YIPF2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009076.1|UniProtKB=W5MRR3 W5MRR3 PTHR22765:SF42 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 150 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004117.1|UniProtKB=W5M963 W5M963 PTHR33775:SF2 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;sarcomere#GO:0030017;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;I band#GO:0031674 LEPOC|Ensembl=ENSLOCG00000004499.1|UniProtKB=W5MAH2 W5MAH2 PTHR46093:SF16 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5 MULTIPLE EGF-LIKE-DOMAINS 8 LEPOC|Ensembl=ENSLOCG00000017208.1|UniProtKB=W5NKW6 W5NKW6 PTHR23004:SF9 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2C supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000082.1|UniProtKB=W5LVD6 W5LVD6 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011210.1|UniProtKB=W5MZG8 W5MZG8 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006065.1|UniProtKB=W5MG24 W5MG24 PTHR13140:SF853 MYOSIN UNCONVENTIONAL MYOSIN-VB ISOFORM X2 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000008518.1|UniProtKB=W5MPQ8 W5MPQ8 PTHR15228:SF16 SPERMATHECAL PHYSIOLOGY VARIANT GEM-INTERACTING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;negative regulation of catalytic activity#GO:0043086;positive regulation of hydrolase activity#GO:0051345;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001846.1|UniProtKB=W5M178 W5M178 PTHR13544:SF7 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T1A-RELATED protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006097.1|UniProtKB=W5MG56 W5MG56 PTHR10811:SF7 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LUNATIC FRINGE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of Notch signaling pathway#GO:0008593 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 LEPOC|Ensembl=ENSLOCG00000011321.1|UniProtKB=W5MZU9 W5MZU9 BANK1 PTHR16267:SF13 BANK1/PIK3AP1 FAMILY MEMBER B-CELL SCAFFOLD PROTEIN WITH ANKYRIN REPEATS enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 negative regulation of biological process#GO:0048519;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of signal transduction#GO:0009966;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;leukocyte activation#GO:0045321;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;lymphocyte activation#GO:0046649;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;regulation of response to stimulus#GO:0048583;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250 LEPOC|Ensembl=ENSLOCG00000007162.1|UniProtKB=W5MJW1 W5MJW1 PTHR11902:SF12 ENOLASE ALPHA-ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 lyase#PC00144 Glycolysis#P00024>Enolase#P00678 LEPOC|Ensembl=ENSLOCG00000009622.1|UniProtKB=W5MTQ5 W5MTQ5 PTHR16501:SF17 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 MITOCHONDRIAL FISSION FACTOR cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;regulation of cellular component organization#GO:0051128;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;establishment of protein localization#GO:0045184;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;regulation of developmental process#GO:0050793;establishment of protein localization to mitochondrion#GO:0072655;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein localization to organelle#GO:0033365;positive regulation of biological process#GO:0048518 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000001636.1|UniProtKB=W5M0H5 W5M0H5 PTHR13048:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;cytosol#GO:0005829;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000996.1|UniProtKB=W5LYB3 W5LYB3 PTHR15460:SF3 PEROXISOMAL MEMBRANE PROTEIN 4 PEROXISOMAL MEMBRANE PROTEIN 4 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012567.1|UniProtKB=W5N4B2 W5N4B2 DMRTA1 PTHR12322:SF71 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sex differentiation#GO:0007548;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004740.1|UniProtKB=W5MBD5 W5MBD5 PTHR15430:SF1 GLOMULIN GLOMULIN enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001981.1|UniProtKB=W5M1N6 W5M1N6 PTHR22804:SF10 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000002349.1|UniProtKB=W5M313 W5M313 PTHR14432:SF6 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 5-AZACYTIDINE-INDUCED PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006609.1|UniProtKB=W5MHX7 W5MHX7 PTHR11904:SF13 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009197.1|UniProtKB=W5MS59 W5MS59 ARF1 PTHR11711:SF357 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000003025.1|UniProtKB=W5M5A5 W5M5A5 PTHR24381:SF445 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF28.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006425.1|UniProtKB=W5MHA3 W5MHA3 PTHR46505:SF1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005947.1|UniProtKB=W5MFM1 W5MFM1 PTHR11829:SF142 FORKHEAD BOX PROTEIN FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015319.1|UniProtKB=W5NDZ1 W5NDZ1 PTHR31077:SF1 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013244.1|UniProtKB=W5N6Q5 W5N6Q5 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003236.1|UniProtKB=W5M614 W5M614 PTHR31905:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012645.1|UniProtKB=W5N4K6 W5N4K6 PTHR48012:SF31 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 10 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010360.1|UniProtKB=W5MWF3 W5MWF3 PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 LEPOC|Ensembl=ENSLOCG00000005863.1|UniProtKB=W5MFE1 W5MFE1 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 16 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004923.1|UniProtKB=W5MC14 W5MC14 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008165.1|UniProtKB=W5MNF1 W5MNF1 PTHR46756:SF4 TRANSGELIN CALPONIN cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006389.1|UniProtKB=W5MHA2 W5MHA2 PTHR11566:SF225 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX-RELATED pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 response to external biotic stimulus#GO:0043207;response to virus#GO:0009615;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;receptor internalization#GO:0031623;membrane organization#GO:0061024;transport#GO:0006810;synaptic vesicle recycling#GO:0036465;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;defense response to virus#GO:0051607;defense response#GO:0006952;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;defense response to symbiont#GO:0140546;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;vesicle budding from membrane#GO:0006900;defense response to other organism#GO:0098542;organelle organization#GO:0006996;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 supramolecular complex#GO:0099080;synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001985.1|UniProtKB=W5M1N8 W5M1N8 PTHR14186:SF23 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PEPTIDASE INHIBITOR DOMAIN 2 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000009293.1|UniProtKB=W5MSH9 W5MSH9 PTHR22763:SF167 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015734.1|UniProtKB=W5NFG1 W5NFG1 PTHR10362:SF7 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001028.1|UniProtKB=W5LYE4 W5LYE4 PTHR34033:SF1 AP-5 COMPLEX SUBUNIT BETA-1 AP-5 COMPLEX SUBUNIT BETA-1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;membrane coat#GO:0030117;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;membrane#GO:0016020;AP-type membrane coat adaptor complex#GO:0030119;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011481.1|UniProtKB=W5N0F0 W5N0F0 PTHR19232:SF10 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2-LIKE LEPOC|Ensembl=ENSLOCG00000003671.1|UniProtKB=W5M7M9 W5M7M9 WDR7 PTHR44099:SF3 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 7 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000517.1|UniProtKB=W5LWR2 W5LWR2 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005309.1|UniProtKB=W5MDE2 W5MDE2 PTHR12411:SF965 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L.1 cysteine-type peptidase activity#GO:0008234;peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;positive regulation of apoptotic signaling pathway#GO:2001235;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004075.1|UniProtKB=W5M910 W5M910 PTHR22808:SF3 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 5-METHYLCYTOSINE RRNA METHYLTRANSFERASE NSUN4 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000013777.1|UniProtKB=W5N8N0 W5N8N0 PTHR23035:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 LEPOC|Ensembl=ENSLOCG00000014615.1|UniProtKB=W5NBH6 W5NBH6 PTHR10807:SF36 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 8 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000001830.1|UniProtKB=W5M159 W5M159 PTHR20531:SF1 N-ALPHA-ACETYLTRANSFERASE 40 N-ALPHA-ACETYLTRANSFERASE 40 histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002018.1|UniProtKB=W5M1V8 W5M1V8 PTHR24264:SF20 TRYPSIN-RELATED TRYPSIN-LIKE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010925.1|UniProtKB=W5MYE4 W5MYE4 IL6ST PTHR23036:SF83 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Signaling subunit#P00969 LEPOC|Ensembl=ENSLOCG00000003788.1|UniProtKB=W5M816 W5M816 PTHR11977:SF33 VILLIN ADVILLIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005930.1|UniProtKB=W5MFJ8 W5MFJ8 PTHR21258:SF44 DOCKING PROTEIN RELATED DOCKING PROTEIN 4 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000261.1|UniProtKB=W5LVX9 W5LVX9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011693.1|UniProtKB=W5N160 W5N160 PTHR14336:SF15 TANDEM PH DOMAIN CONTAINING PROTEIN DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE LEPOC|Ensembl=ENSLOCG00000009093.1|UniProtKB=W5MRS9 W5MRS9 PTHR21964:SF16 BREAST CANCER METASTASIS-SUPPRESSOR 1 BREAST CANCER METASTASIS-SUPPRESSOR 1-LIKE PROTEIN enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000003202.1|UniProtKB=W5M5X8 W5M5X8 PTHR31548:SF5 CLARIN CLARIN-2 LEPOC|Ensembl=ENSLOCG00000015064.1|UniProtKB=W5ND32 W5ND32 PTHR13403:SF6 SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1 SNURPORTIN-1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005876.1|UniProtKB=W5MFD5 W5MFD5 PTHR31097:SF2 SI:DKEY-276J7.1 CHROMOSOME 7 OPEN READING FRAME 57 LEPOC|Ensembl=ENSLOCG00000005913.1|UniProtKB=W5MFI4 W5MFI4 PTHR11579:SF4 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000011403.1|UniProtKB=W5N061 W5N061 PTHR12428:SF65 OXA1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;protein localization#GO:0008104 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006636.1|UniProtKB=W5MI06 W5MI06 PTHR46788:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010052.1|UniProtKB=W5MV86 W5MV86 PTHR14614:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN METHYLTRANSFERASE-LIKE PROTEIN 21E PSEUDOGENE-RELATED protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017206.1|UniProtKB=W5NKW3 W5NKW3 PTHR22948:SF7 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 15 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016897.1|UniProtKB=W5NJS7 W5NJS7 PTHR15141:SF49 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 TFIIS N-TERMINAL DOMAIN-CONTAINING PROTEIN general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001568.1|UniProtKB=W5M088 W5M088 PTHR24034:SF146 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-7-LIKE extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000016962.1|UniProtKB=W5NK11 W5NK11 PTHR24205:SF7 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 5 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012016.1|UniProtKB=W5N2C1 W5N2C1 PTHR11690:SF128 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015989.1|UniProtKB=W5NGC6 W5NGC6 PTHR13318:SF240 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 13 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000012123.1|UniProtKB=W5N2Q7 W5N2Q7 PTHR15379:SF2 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of growth#GO:0040008;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558 LEPOC|Ensembl=ENSLOCG00000010491.1|UniProtKB=W5MWU9 W5MWU9 PTHR14499:SF28 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD16 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277 presynapse#GO:0098793;receptor complex#GO:0043235;synapse#GO:0045202;protein-containing complex#GO:0032991;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009738.1|UniProtKB=W5MU42 W5MU42 PTHR10728:SF32 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 BETA cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 Oxidative stress response#P00046>cPLA2#P01134;Angiogenesis#P00005>PLA2#P00227;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855;VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000011161.1|UniProtKB=W5MZC2 W5MZC2 PTHR12100:SF0 SEC10 EXOCYST COMPLEX COMPONENT 5 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007107.1|UniProtKB=W5MJP7 W5MJP7 PTHR12299:SF29 HYALURONIC ACID-BINDING PROTEIN 4 SERPINE1 MRNA-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010693.1|UniProtKB=W5MXJ3 W5MXJ3 PTHR24060:SF147 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000004414.1|UniProtKB=W5MA65 W5MA65 PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018128.1|UniProtKB=W5NNM0 W5NNM0 PTHR11984:SF52 CONNEXIN GAP JUNCTION GAMMA-2 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000004971.1|UniProtKB=W5MC89 W5MC89 NELL1 PTHR24042:SF2 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL1 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;glycosaminoglycan binding#GO:0005539;kinase binding#GO:0019900 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000014272.1|UniProtKB=W5NAB7 W5NAB7 PTHR10677:SF25 UBIQUILIN UBIQUITIN-LIKE PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016892.1|UniProtKB=W5NJS2 W5NJS2 PTHR13738:SF38 TROPONIN I NOVEL PROTEIN (ZGC:92233)-RELATED blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000010846.1|UniProtKB=W5MY32 W5MY32 MSX2 PTHR24338:SF10 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011242.1|UniProtKB=W5MZK7 W5MZK7 PTHR14614:SF44 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21D cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011643.1|UniProtKB=W5N0Z9 W5N0Z9 PTHR22948:SF73 TUDOR DOMAIN CONTAINING PROTEIN SERINE_THREONINE-PROTEIN KINASE 31 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016707.1|UniProtKB=W5NJ30 W5NJ30 PTHR18874:SF10 CMF/LEK/CENP CELL DIVISION-RELATED CENTROMERE PROTEIN F protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;regulation of cell cycle G2/M phase transition#GO:1902749;organelle localization#GO:0051640;establishment of chromosome localization#GO:0051303;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;chromosome segregation#GO:0007059;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;chromosome localization#GO:0050000;establishment of organelle localization#GO:0051656;metaphase chromosome alignment#GO:0051310;regulation of mitotic cell cycle#GO:0007346 spindle pole#GO:0000922;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000007013.1|UniProtKB=W5MJE6 W5MJE6 PTHR15036:SF15 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4B cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015094.1|UniProtKB=W5ND70 W5ND70 PTHR23509:SF7 PA-PL1 PHOSPHOLIPASE FAMILY PHOSPHOLIPASE DDHD2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012707.1|UniProtKB=W5N4S7 W5N4S7 PTHR22942:SF39 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;double-stranded DNA binding#GO:0003690 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010646.1|UniProtKB=W5MXC6 W5MXC6 PTHR24241:SF89 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OXYTOCIN RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;signal transduction#GO:0007165;system process#GO:0003008;regulation of system process#GO:0044057;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;reproductive process#GO:0022414;positive regulation of biological process#GO:0048518;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;response to organic substance#GO:0010033;regulation of anatomical structure size#GO:0090066;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;multicellular organism reproduction#GO:0032504;cell communication#GO:0007154;regulation of systemic arterial blood pressure#GO:0003073;cellular process#GO:0009987;circulatory system process#GO:0003013;response to stimulus#GO:0050896;reproduction#GO:0000003;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of blood pressure#GO:0008217;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Oxytocin receptor mediated signaling pathway#P04391>Oxytocin Receptor#P04531 LEPOC|Ensembl=ENSLOCG00000011558.1|UniProtKB=W5N0P8 W5N0P8 PPP2R5C PTHR10257:SF3 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000000948.1|UniProtKB=W5LY48 W5LY48 PTHR46780:SF23 PROTEIN EVA-1 PROTEIN EVA-1 HOMOLOG A LEPOC|Ensembl=ENSLOCG00000006461.1|UniProtKB=W5MHE6 W5MHE6 PTHR31139:SF5 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;protein-containing complex organization#GO:0043933;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagosome maturation#GO:0097352;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006196.1|UniProtKB=W5MGH6 W5MGH6 PTHR12619:SF23 RFX TRANSCRIPTION FACTOR FAMILY MHC CLASS II REGULATORY FACTOR RFX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015118.1|UniProtKB=W5ND95 W5ND95 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 HIV TAT-SPECIFIC FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;U2 snRNP#GO:0005686;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002749.1|UniProtKB=W5M4E4 W5M4E4 SPATA5 PTHR23077:SF27 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014318.1|UniProtKB=W5NAH4 W5NAH4 CFP PTHR22906:SF43 PROPERDIN PROPERDIN LEPOC|Ensembl=ENSLOCG00000016356.1|UniProtKB=W5NHT7 W5NHT7 PTHR43671:SF13 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004142.1|UniProtKB=W5M993 W5M993 PTHR20859:SF85 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA_BETA RECEPTOR 1 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011731.1|UniProtKB=W5N1A9 W5N1A9 PITX2 PTHR45882:SF4 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 LEPOC|Ensembl=ENSLOCG00000008378.1|UniProtKB=W5MP71 W5MP71 COBLL1 PTHR21557:SF2 CORDON-BLEU CORDON-BLEU PROTEIN-LIKE 1 LEPOC|Ensembl=ENSLOCG00000017234.1|UniProtKB=W5NL07 W5NL07 PTHR14680:SF1 SI:DKEY-126G1.9-RELATED REQUIRED FOR DRUG-INDUCED DEATH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003293.1|UniProtKB=W5M679 W5M679 PTHR45740:SF7 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011661.1|UniProtKB=W5N132 W5N132 PTHR23122:SF45 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS2 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009960.1|UniProtKB=W5MUY2 W5MUY2 PTHR21345:SF8 SPIRE PROTEIN SPIRE HOMOLOG 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell division#GO:0051301;organelle localization#GO:0051640;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament organization#GO:0007015;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;spindle localization#GO:0051653;multicellular organismal reproductive process#GO:0048609;cellular component assembly#GO:0022607;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;vesicle-mediated transport#GO:0016192;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of spindle localization#GO:0051293;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010322.1|UniProtKB=W5MW97 W5MW97 PTHR12745:SF11 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000002236.1|UniProtKB=W5M2J8 W5M2J8 PTHR12290:SF13 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;regulation of cell communication#GO:0010646;regulation of transmembrane transport#GO:0034762;cellular localization#GO:0051641;transport#GO:0006810;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;intracellular transport#GO:0046907;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409 synapse#GO:0045202;somatodendritic compartment#GO:0036477;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell junction#GO:0030054;dendrite#GO:0030425;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;organelle#GO:0043226;coated vesicle#GO:0030135;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003765.1|UniProtKB=W5M807 W5M807 PTHR18884:SF115 SEPTIN SEPTIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell division#GO:0051301;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;plasma membrane bounded cell projection assembly#GO:0120031;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001976.1|UniProtKB=W5M1N9 W5M1N9 PTHR45872:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 11 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003777.1|UniProtKB=W5M811 W5M811 PTHR24023:SF1113 COLLAGEN ALPHA COLLAGEN ALPHA-2(IX) CHAIN-LIKE ISOFORM X1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000010744.1|UniProtKB=W5MXQ5 W5MXQ5 PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009826.1|UniProtKB=W5MUF6 W5MUF6 PTHR10131:SF76 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 3 protein binding#GO:0005515;tumor necrosis factor receptor binding#GO:0005164;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of cell communication#GO:0010646;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;negative regulation of DNA-binding transcription factor activity#GO:0043433 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016322.1|UniProtKB=W5NHP2 W5NHP2 PTHR23104:SF14 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007935.1|UniProtKB=W5MMN5 W5MMN5 PTHR45742:SF4 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C6 activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000017138.1|UniProtKB=W5NKM5 W5NKM5 PTHR24416:SF527 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009201.1|UniProtKB=W5MS61 W5MS61 PTHR31740:SF2 CENTROMERE PROTEIN L CENTROMERE PROTEIN L LEPOC|Ensembl=ENSLOCG00000009351.1|UniProtKB=W5MSQ5 W5MSQ5 PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008237.1|UniProtKB=W5MNP2 W5MNP2 CCDC157 PTHR43696:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 LEPOC|Ensembl=ENSLOCG00000006899.1|UniProtKB=W5MJ10 W5MJ10 PTHR11920:SF300 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 1 adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000010351.1|UniProtKB=W5MWC7 W5MWC7 PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 pyrophosphatase#PC00196 LEPOC|Ensembl=ENSLOCG00000014394.1|UniProtKB=W5NAR3 W5NAR3 PTHR11588:SF239 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015993.1|UniProtKB=W5NGD4 W5NGD4 PTHR32083:SF34 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 146 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010501.1|UniProtKB=W5MX16 W5MX16 PTHR24254:SF6 PROTHROMBIN CUBILIN serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017516.1|UniProtKB=W5NLW2 W5NLW2 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 negative regulation of biological process#GO:0048519;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;protein folding#GO:0006457;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CCKR signaling map#P06959>HSP27#P07154;VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231;p38 MAPK pathway#P05918>HSP27#P06016 LEPOC|Ensembl=ENSLOCG00000004775.1|UniProtKB=W5MBI3 W5MBI3 PTHR45819:SF1 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;ribonucleoside triphosphate phosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008766.1|UniProtKB=W5MQL4 W5MQL4 PTHR46062:SF2 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000005495.1|UniProtKB=W5ME27 W5ME27 PTHR12844:SF10 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 1 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>CNKSR1#P07029 LEPOC|Ensembl=ENSLOCG00000006209.1|UniProtKB=W5MGJ1 W5MGJ1 PTHR18966:SF407 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated channel activity#GO:0022832;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 signal transduction#GO:0007165;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of postsynaptic membrane potential#GO:0060078;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NR2A#P01008;Ionotropic glutamate receptor pathway#P00037>NR2C#P01006 LEPOC|Ensembl=ENSLOCG00000001086.1|UniProtKB=W5LYL6 W5LYL6 PTHR31543:SF0 DYNEIN REGULATORY COMPLEX SUBUNIT 4 DYNEIN REGULATORY COMPLEX SUBUNIT 4 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014068.1|UniProtKB=W5N9N3 W5N9N3 PTHR22406:SF4 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 2 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;cytoplasmic microtubule organization#GO:0031122;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;microtubule nucleation#GO:0007020 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001807.1|UniProtKB=W5M156 W5M156 PTHR10030:SF2 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000018351.1|UniProtKB=W5NP93 W5NP93 PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000011518.1|UniProtKB=W5N0J3 W5N0J3 PTHR12864:SF56 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 9 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012767.1|UniProtKB=W5N508 W5N508 PTHR12881:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to organic substance#GO:0071310;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000004523.1|UniProtKB=W5MAK0 W5MAK0 PTHR11830:SF17 40S RIBOSOMAL PROTEIN S3A CYLINDROMATOSIS (TURBAN TUMOR SYNDROME), B cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein K63-linked deubiquitination#GO:0070536;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003096.1|UniProtKB=W5M5K1 W5M5K1 PTHR23277:SF121 NECTIN-RELATED IMMUNOGLOBULIN SUPERFAMILY MEMBER 21 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000018102.1|UniProtKB=W5NNJ4 W5NNJ4 PTHR48050:SF13 STEROL 3-BETA-GLUCOSYLTRANSFERASE STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009586.1|UniProtKB=W5MTK5 W5MTK5 PTHR14187:SF46 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A LEPOC|Ensembl=ENSLOCG00000009824.1|UniProtKB=W5MUE5 W5MUE5 PTHR22749:SF6 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Flavin biosynthesis#P02741>Riboflavin kinase#P02934;Flavin biosynthesis#P02741>FAD synthetase#P02936 LEPOC|Ensembl=ENSLOCG00000008287.1|UniProtKB=W5MNV3 W5MNV3 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000016463.1|UniProtKB=W5NI80 W5NI80 PTHR13768:SF12 SOLUBLE NSF ATTACHMENT PROTEIN SNAP BETA-SOLUBLE NSF ATTACHMENT PROTEIN syntaxin binding#GO:0019905;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;cellular component disassembly#GO:0022411;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component biogenesis#GO:0044087;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;protein-containing complex disassembly#GO:0032984;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;synaptic transmission, glutamatergic#GO:0035249 bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;cell junction#GO:0030054;SNARE complex#GO:0031201;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005385.1|UniProtKB=W5MDN2 W5MDN2 PTHR19957:SF139 SYNTAXIN SYNTAXIN-17 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;export from cell#GO:0140352;secretion by cell#GO:0032940;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015893.1|UniProtKB=W5NG14 W5NG14 PTHR19134:SF461 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012592.1|UniProtKB=W5N4E1 W5N4E1 PSRC1 PTHR21584:SF1 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 PROLINE_SERINE-RICH COILED-COIL PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;establishment of localization#GO:0051234;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;mitotic sister chromatid segregation#GO:0000070;chromosome localization#GO:0050000;establishment of organelle localization#GO:0051656;metaphase chromosome alignment#GO:0051310 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle microtubule#GO:0005876;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000017215.1|UniProtKB=W5NKX5 W5NKX5 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000011599.1|UniProtKB=W5N0V6 W5N0V6 PTHR10288:SF158 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;mRNA stabilization#GO:0048255;multicellular organism development#GO:0007275;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003970.1|UniProtKB=W5M8N3 W5M8N3 PTHR22599:SF1 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000013836.1|UniProtKB=W5N8W2 W5N8W2 PTHR24291:SF193 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000929.1|UniProtKB=W5LY32 W5LY32 PTHR10489:SF686 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 5 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000005878.1|UniProtKB=W5MFE3 W5MFE3 PTHR24367:SF17 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014478.1|UniProtKB=W5NB25 W5NB25 PTHR11533:SF172 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE N metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017380.1|UniProtKB=W5NLH6 W5NLH6 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018205.1|UniProtKB=W5NNU7 W5NNU7 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017114.1|UniProtKB=W5NKJ3 W5NKJ3 PTHR12292:SF2 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000010073.1|UniProtKB=W5MVB1 W5MVB1 SPATA1 PTHR14421:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017374.1|UniProtKB=W5NLH0 W5NLH0 GPR87 PTHR24233:SF8 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 87 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018226.1|UniProtKB=W5NNW8 W5NNW8 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014000.1|UniProtKB=W5N9E5 W5N9E5 PTHR24340:SF33 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013333.1|UniProtKB=W5N724 W5N724 PTHR24350:SF4 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE B mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;spindle organization#GO:0007051;regulation of cytokinesis#GO:0032465 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;midbody#GO:0030496;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012875.1|UniProtKB=W5N5E0 W5N5E0 PTHR31278:SF2 CHCHD1 SMALL RIBOSOMAL SUBUNIT PROTEIN MS37 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 LEPOC|Ensembl=ENSLOCG00000007958.1|UniProtKB=W5MMQ7 W5MMQ7 PTHR12281:SF31 RP42 RELATED DCN1-LIKE PROTEIN 3 cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014938.1|UniProtKB=W5NCN6 W5NCN6 PTHR46983:SF2 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 INTEGRIN SUBUNIT BETA 1 BINDING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015264.1|UniProtKB=W5NDS5 W5NDS5 PTHR10663:SF338 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 4 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005226.1|UniProtKB=W5MD42 W5MD42 PTHR24027:SF85 CADHERIN-23 CADHERIN-11 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000009005.1|UniProtKB=W5MRG6 W5MRG6 PTHR23347:SF4 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED COLORECTAL MUTANT CANCER PROTEIN LEPOC|Ensembl=ENSLOCG00000006997.1|UniProtKB=W5MJC5 W5MJC5 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 cyclase#PC00079;guanylate cyclase#PC00114;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000015657.1|UniProtKB=W5NF65 W5NF65 PTHR10183:SF409 CALPAIN CALPAIN-8 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017444.1|UniProtKB=W5NLP0 W5NLP0 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002169.1|UniProtKB=W5M2B3 W5M2B3 PTHR24399:SF27 ZINC FINGER AND BTB DOMAIN-CONTAINING HYPERMETHYLATED IN CANCER 2 PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008454.1|UniProtKB=W5MPH7 W5MPH7 PTHR23276:SF2 PROTEIN PRRC1 PROTEIN PRRC1 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011230.1|UniProtKB=W5MZK1 W5MZK1 PTHR11361:SF21 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 4 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014269.1|UniProtKB=W5NAB4 W5NAB4 PTHR23429:SF0 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;hexose metabolic process#GO:0019318;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005898.1|UniProtKB=W5MFG8 W5MFG8 KDM1B PTHR10742:SF410 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010816.1|UniProtKB=W5MXZ2 W5MXZ2 PTHR46829:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000010731.1|UniProtKB=W5MXP3 W5MXP3 PTHR24092:SF79 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VB ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011497.1|UniProtKB=W5N0H0 W5N0H0 PTHR22793:SF6 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR A transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;muscle cell differentiation#GO:0042692;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005943.1|UniProtKB=W5MFM0 W5MFM0 PTHR46292:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102A LEPOC|Ensembl=ENSLOCG00000010447.1|UniProtKB=W5MWP4 W5MWP4 PTHR22930:SF289 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000011521.1|UniProtKB=W5N0J9 W5N0J9 PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 LEPOC|Ensembl=ENSLOCG00000004007.1|UniProtKB=W5M8S7 W5M8S7 PTHR12232:SF3 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014580.1|UniProtKB=W5NBD8 W5NBD8 PTHR10865:SF5 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;enzyme binding#GO:0019899;protein binding#GO:0005515 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003261.1|UniProtKB=W5M643 W5M643 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000008702.1|UniProtKB=W5MQE4 W5MQE4 PTHR11139:SF1 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001124.1|UniProtKB=W5LYR1 W5LYR1 AK2 PTHR23359:SF234 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000007645.1|UniProtKB=W5MLL3 W5MLL3 PTHR10665:SF2 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS-LIKE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Notch signaling pathway#P00045>Su(H)#P01101;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Angiogenesis#P00005>CSL#P00233 LEPOC|Ensembl=ENSLOCG00000016654.1|UniProtKB=W5NIW5 W5NIW5 PKDREJ PTHR10877:SF185 POLYCYSTIN FAMILY MEMBER POLYCYSTIN FAMILY RECEPTOR FOR EGG JELLY calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006949.1|UniProtKB=W5MJ58 W5MJ58 PTHR22802:SF402 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER E membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008564.1|UniProtKB=W5MPW0 W5MPW0 GATB PTHR11659:SF0 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015947.1|UniProtKB=W5NG76 W5NG76 PTHR15427:SF1 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003394.1|UniProtKB=W5M6L0 W5M6L0 PTHR33504:SF1 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 FAMILY WITH SEQUENCE SIMILARITY 90, MEMBER A1B dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016969.1|UniProtKB=W5NK17 W5NK17 PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012425.1|UniProtKB=W5N3T6 W5N3T6 MFAP3 PTHR14340:SF4 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 LEPOC|Ensembl=ENSLOCG00000003020.1|UniProtKB=W5M596 W5M596 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015030.1|UniProtKB=W5NCZ3 W5NCZ3 PTHR24340:SF115 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008628.1|UniProtKB=W5MQ46 W5MQ46 PTHR13743:SF64 BEIGE/BEACH-RELATED LIPOPOLYSACCHARIDE-RESPONSIVE AND BEIGE-LIKE ANCHOR PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004483.1|UniProtKB=W5MAE8 W5MAE8 PTHR21472:SF28 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 EXTRACELLULAR ENDONUCLEASE SUBUNIT A DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013265.1|UniProtKB=W5N6T8 W5N6T8 PTHR13677:SF1 LD41638P PROTEIN DENND6A cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007688.1|UniProtKB=W5MLT5 W5MLT5 PTHR11705:SF20 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012510.1|UniProtKB=W5N447 W5N447 PTHR13976:SF60 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015782.1|UniProtKB=W5NFM1 W5NFM1 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009435.1|UniProtKB=W5MT01 W5MT01 PTHR10264:SF117 BAND 7 PROTEIN-RELATED ERYTHROCYTE BAND 7 INTEGRAL MEMBRANE PROTEIN-LIKE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000007586.1|UniProtKB=W5MLE6 W5MLE6 PTHR12247:SF84 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014694.1|UniProtKB=W5NBS9 W5NBS9 PTHR11240:SF85 RIBONUCLEASE T2 RIBONUCLEASE T2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009985.1|UniProtKB=W5MV02 W5MV02 RD3L PTHR28489:SF3 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3-LIKE LEPOC|Ensembl=ENSLOCG00000014572.1|UniProtKB=W5NBC2 W5NBC2 PTHR11849:SF178 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>ELK#P00962;Gonadotropin-releasing hormone receptor pathway#P06664>ELK1#P06785;p38 MAPK pathway#P05918>ELK#P06013;PDGF signaling pathway#P00047>ELK#P01140;Ras Pathway#P04393>Elk-1#P04573;Oxidative stress response#P00046>Elk-1#P01136;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ELK#P00890;CCKR signaling map#P06959>ELK1#P07146;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>ELK1#P05934;Toll receptor signaling pathway#P00054>Elk1#P01341;Parkinson disease#P00049>Elk-1#P01233 LEPOC|Ensembl=ENSLOCG00000000421.1|UniProtKB=W5LWF0 W5LWF0 PTHR15907:SF107 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000016732.1|UniProtKB=W5NJ68 W5NJ68 PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000006336.1|UniProtKB=W5MH10 W5MH10 ERAP2 PTHR11533:SF239 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017741.1|UniProtKB=W5NMI6 W5NMI6 PTHR10484:SF212 HISTONE H4 HISTONE H4 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014763.1|UniProtKB=W5NC18 W5NC18 PTHR12489:SF17 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 4B multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;sensory perception of sound#GO:0007605;system process#GO:0003008 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004554.1|UniProtKB=W5MAP8 W5MAP8 PTHR22906:SF52 PROPERDIN ADHESION G PROTEIN-COUPLED RECEPTOR B1 LEPOC|Ensembl=ENSLOCG00000000625.1|UniProtKB=W5LX34 W5LX34 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007423.1|UniProtKB=W5MKU6 W5MKU6 PTHR16125:SF4 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74B LEPOC|Ensembl=ENSLOCG00000004995.1|UniProtKB=W5MCB6 W5MCB6 PTHR12233:SF5 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005165.1|UniProtKB=W5MCW1 W5MCW1 PTHR13059:SF10 HMG-BOX TRANSCRIPTION FACTOR BBX HMG BOX TRANSCRIPTION FACTOR BBX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000007097.1|UniProtKB=W5MJN1 W5MJN1 PTHR45701:SF1 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 1 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000005123.1|UniProtKB=W5MCQ8 W5MCQ8 PTHR12669:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 2 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005624.1|UniProtKB=W5MEJ4 W5MEJ4 PTHR19384:SF56 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE, INDUCIBLE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor#GO:0016653;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;system process#GO:0003008;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;alpha-amino acid metabolic process#GO:1901605;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;regulation of lyase activity#GO:0051339;response to oxygen-containing compound#GO:1901700;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;circulatory system process#GO:0003013;organic acid metabolic process#GO:0006082;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;blood circulation#GO:0008015;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;response to lipid#GO:0033993;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;amino acid catabolic process#GO:0009063;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;L-amino acid metabolic process#GO:0170033;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;proteinogenic amino acid metabolic process#GO:0170039;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;arginine metabolic process#GO:0006525;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of blood pressure#GO:0008217;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of lyase activity#GO:0051349;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 oxidoreductase#PC00176 PI3 kinase pathway#P00048>NOS#P01205 LEPOC|Ensembl=ENSLOCG00000005686.1|UniProtKB=W5MEQ7 W5MEQ7 PTHR10655:SF22 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008140.1|UniProtKB=W5MNC2 W5MNC2 PTHR22611:SF1 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 2 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>Naked#P01427 LEPOC|Ensembl=ENSLOCG00000017737.1|UniProtKB=W5NMI2 W5NMI2 PTHR24070:SF269 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005255.1|UniProtKB=W5MD84 W5MD84 PTHR11447:SF21 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN P73 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 P53 pathway feedback loops 1#P04392>p53#P04539;P53 pathway feedback loops 1#P04392>p73#G04686;p53 pathway feedback loops 2#P04398>p53#P04668;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#G04702;p53 pathway by glucose deprivation#P04397>p53#P04640;p53 pathway#P00059>p53#P01485 LEPOC|Ensembl=ENSLOCG00000010029.1|UniProtKB=W5MV51 W5MV51 PTHR22961:SF17 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007796.1|UniProtKB=W5MM65 W5MM65 SLC9A9 PTHR10110:SF61 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 9 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010640.1|UniProtKB=W5MXB9 W5MXB9 PTHR23248:SF38 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 1 phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010984.1|UniProtKB=W5MYL0 W5MYL0 PTHR15941:SF16 MYOZENIN MYOZENIN 3A-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 supramolecular complex#GO:0099080;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007711.1|UniProtKB=W5MLV4 W5MLV4 HECTD4 PTHR46435:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005897.1|UniProtKB=W5MFG6 W5MFG6 PTHR36542:SF2 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DRED-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010172.1|UniProtKB=W5MVN6 W5MVN6 PTHR12015:SF183 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 3 cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000014309.1|UniProtKB=W5NAG0 W5NAG0 PRSS16 PTHR11010:SF11 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED THYMUS-SPECIFIC SERINE PROTEASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003082.1|UniProtKB=W5M5H7 W5M5H7 PTHR13989:SF16 REPLICATION PROTEIN A-RELATED REPLICATION PROTEIN A2 DNA replication#P00017>RPA#P00537 LEPOC|Ensembl=ENSLOCG00000006163.1|UniProtKB=W5MGG0 W5MGG0 PTHR21502:SF8 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1L organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012137.1|UniProtKB=W5N2T1 W5N2T1 PTHR23509:SF32 PA-PL1 PHOSPHOLIPASE FAMILY PHOSPHOLIPASE DDHD1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003975.1|UniProtKB=W5M8S9 W5M8S9 PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000742.1|UniProtKB=W5LXG8 W5LXG8 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006418.1|UniProtKB=W5MH94 W5MH94 PTHR13680:SF41 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON SULFUR DOMAIN 1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000008706.1|UniProtKB=W5MQD5 W5MQD5 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN protein binding#GO:0005515;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000003732.1|UniProtKB=W5M7T6 W5M7T6 PTHR10075:SF52 BASIGIN RELATED NEXILIN cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;Z disc#GO:0030018;anchoring junction#GO:0070161;cell junction#GO:0030054;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;contractile fiber#GO:0043292;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;focal adhesion#GO:0005925;sarcomere#GO:0030017;cell-substrate junction#GO:0030055;cell projection#GO:0042995;myofibril#GO:0030016;I band#GO:0031674;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016051.1|UniProtKB=W5NGL5 W5NGL5 PTHR43038:SF3 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 ABC TRANSPORTER G FAMILY MEMBER 20 ISOFORM X1 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005408.1|UniProtKB=W5MDV6 W5MDV6 PTHR10730:SF5 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein hydroxylation#GO:0018126;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004942.1|UniProtKB=W5MC50 W5MC50 PTHR19376:SF32 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000001082.1|UniProtKB=W5LYL4 W5LYL4 PTHR44321:SF1 TRANSDUCIN BETA-LIKE PROTEIN 2 TRANSDUCIN BETA-LIKE PROTEIN 2 response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012040.1|UniProtKB=W5N2F1 W5N2F1 PTHR14557:SF4 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 2 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000015974.1|UniProtKB=W5NGA7 W5NGA7 PTHR19282:SF154 TETRASPANIN TETRASPANIN-33 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001133.1|UniProtKB=W5LYR9 W5LYR9 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC-CHELATE REDUCTASE 1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008512.1|UniProtKB=W5MPQ0 W5MPQ0 PTHR11103:SF10 SLR1189 PROTEIN HOMOCYSTEINE S-METHYLTRANSFERASE 1-RELATED Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953 LEPOC|Ensembl=ENSLOCG00000003178.1|UniProtKB=W5M5U5 W5M5U5 PTHR23274:SF51 DNA HELICASE-RELATED OS03G0423850 PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;DNA geometric change#GO:0032392;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;DNA duplex unwinding#GO:0032508;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002625.1|UniProtKB=W5M3Y8 W5M3Y8 PTHR13713:SF95 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE- ALPHA-2,3-SIALYLTRANSFERASE 4 ISOFORM 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016123.1|UniProtKB=W5NGV8 W5NGV8 PTHR21568:SF0 TRNA PSEUDOURIDINE SYNTHASE PUS10 TRNA PSEUDOURIDINE SYNTHASE PUS10 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000007193.1|UniProtKB=W5MJZ4 W5MJZ4 PTHR16551:SF1 AGOUTI RELATED AGOUTI-SIGNALING PROTEIN neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 pigmentation#GO:0043473;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;melanosome organization#GO:0032438 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007764.1|UniProtKB=W5MM21 W5MM21 PTHR10517:SF14 FOLATE RECEPTOR FOLATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016685.1|UniProtKB=W5NJ04 W5NJ04 PTHR19143:SF466 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011856.1|UniProtKB=W5N1S0 W5N1S0 PTHR32261:SF7 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 3 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000000464.1|UniProtKB=W5LWK1 W5LWK1 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 LEPOC|Ensembl=ENSLOCG00000003095.1|UniProtKB=W5M5J3 W5M5J3 SUSD2 PTHR13802:SF63 MUCIN 4-RELATED SUSHI DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016708.1|UniProtKB=W5NJ31 W5NJ31 PTHR12879:SF2 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000010906.1|UniProtKB=W5MYC1 W5MYC1 PTHR16027:SF4 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-INTERACTING PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;vasculature development#GO:0001944;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;regulation of Rho protein signal transduction#GO:0035023;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of GTPase activity#GO:0043087;negative regulation of signaling#GO:0023057;tube development#GO:0035295;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;developmental process#GO:0032502;regulation of catalytic activity#GO:0050790;system development#GO:0048731;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of small GTPase mediated signal transduction#GO:0051058;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;negative regulation of phosphorus metabolic process#GO:0010563;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of phosphate metabolic process#GO:0045936;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 LEPOC|Ensembl=ENSLOCG00000001197.1|UniProtKB=W5LZ19 W5LZ19 PTHR43899:SF14 RH59310P VERY-LONG-CHAIN 3-OXOACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009743.1|UniProtKB=W5MU47 W5MU47 RGS22 PTHR46583:SF1 REGULATOR OF G-PROTEIN SIGNALING 22 REGULATOR OF G-PROTEIN SIGNALING 22 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017836.1|UniProtKB=W5NMT0 W5NMT0 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;neutrophil migration#GO:1990266;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;granulocyte migration#GO:0097530;neutrophil chemotaxis#GO:0030593;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;myeloid leukocyte migration#GO:0097529;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;leukocyte chemotaxis#GO:0030595;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000008265.1|UniProtKB=W5MNS9 W5MNS9 PTHR45992:SF2 EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED EUKARYOTIC ELONGATION FACTOR 2 KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;protein-containing complex disassembly#GO:0032984;response to oxygen-containing compound#GO:1901700;cellular component organization#GO:0016043;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular component disassembly#GO:0022411;response to chemical#GO:0042221;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 Oxidative stress response#P00046>eEF2K#P01127;p38 MAPK pathway#P05918>eEF2K#P06022 LEPOC|Ensembl=ENSLOCG00000000046.1|UniProtKB=W5LV97 W5LV97 PTHR24055:SF561 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 7 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>MAPK7#P07021;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>ERK1-2#P00627;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 LEPOC|Ensembl=ENSLOCG00000007269.1|UniProtKB=W5MK88 W5MK88 PTHR46075:SF1 CHIMERIN FAMILY MEMBER N-CHIMAERIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 LEPOC|Ensembl=ENSLOCG00000016616.1|UniProtKB=W5NIR5 W5NIR5 PTHR24329:SF362 HOMEOBOX PROTEIN ARISTALESS INTESTINE-SPECIFIC HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001702.1|UniProtKB=W5M0R2 W5M0R2 PTHR15592:SF19 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010092.1|UniProtKB=W5MVD8 W5MVD8 PTHR15315:SF106 RING FINGER PROTEIN 41, 151 RING-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002707.1|UniProtKB=W5M479 W5M479 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000006141.1|UniProtKB=W5MGD3 W5MGD3 PTHR24348:SF19 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;macroautophagy#GO:0016236;regulation of catabolic process#GO:0009894;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component organization#GO:0051129;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;reticulophagy#GO:0061709;response to stress#GO:0006950;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;positive regulation of catabolic process#GO:0009896;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;autophagosome assembly#GO:0000045;positive regulation of autophagy#GO:0010508;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule modification#GO:0043412;developmental process#GO:0032502;positive regulation of cellular catabolic process#GO:0031331;protein modification process#GO:0036211;growth#GO:0040007;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;axon extension#GO:0048675;neuron differentiation#GO:0030182;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;regulation of cell development#GO:0060284;developmental growth#GO:0048589;regulation of autophagy#GO:0010506;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;cell growth#GO:0016049;organelle disassembly#GO:1903008;regulation of cellular component size#GO:0032535;organelle assembly#GO:0070925;cell development#GO:0048468;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of cell size#GO:0008361;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;response to starvation#GO:0042594;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;generation of neurons#GO:0048699 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005820.1|UniProtKB=W5MF72 W5MF72 PTHR10517:SF19 FOLATE RECEPTOR RETBINDIN signaling receptor activity#GO:0038023;transmembrane transporter activity#GO:0022857;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010163.1|UniProtKB=W5MVM8 W5MVM8 PTHR14684:SF2 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000011855.1|UniProtKB=W5N1S1 W5N1S1 PTHR10173:SF37 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B2, MITOCHONDRIAL oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009273.1|UniProtKB=W5MSG1 W5MSG1 DNA2 PTHR10887:SF433 DNA2/NAM7 HELICASE FAMILY DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 DNA replication#P00017>Hel#P00532 LEPOC|Ensembl=ENSLOCG00000001251.1|UniProtKB=W5LZ65 W5LZ65 PTHR16127:SF10 TAXILIN BETA-TAXILIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017365.1|UniProtKB=W5NLG1 W5NLG1 PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016024.1|UniProtKB=W5NGH6 W5NGH6 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;maturation of 5.8S rRNA#GO:0000460;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012709.1|UniProtKB=W5N4S6 W5N4S6 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED LEPOC|Ensembl=ENSLOCG00000011938.1|UniProtKB=W5N227 W5N227 PTHR12277:SF69 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD12B hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013682.1|UniProtKB=W5N8B0 W5N8B0 WWC2 PTHR14791:SF26 BOMB/KIRA PROTEINS PROTEIN WWC2 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;cell motility#GO:0048870;regulation of RNA biosynthetic process#GO:2001141;regulation of growth#GO:0040008;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell migration#GO:0016477;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015580.1|UniProtKB=W5NEX2 W5NEX2 LSM8 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014308.1|UniProtKB=W5NAF9 W5NAF9 PTHR12411:SF642 CYSTEINE PROTEASE FAMILY C1-RELATED PRO-CATHEPSIN H cysteine-type peptidase activity#GO:0008234;peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;positive regulation of apoptotic signaling pathway#GO:2001235;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016808.1|UniProtKB=W5NJG6 W5NJG6 PTHR22914:SF42 CHITIN SYNTHASE CHITIN SYNTHASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;amino sugar metabolic process#GO:0006040;aminoglycan metabolic process#GO:0006022;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell septum#GO:0030428 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015025.1|UniProtKB=W5NCY6 W5NCY6 PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000003220.1|UniProtKB=W5M5Z3 W5M5Z3 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;EGF receptor signaling pathway#P00018>Ras#P00552 LEPOC|Ensembl=ENSLOCG00000013529.1|UniProtKB=W5N7S6 W5N7S6 PTHR11024:SF2 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;protein transport#GO:0015031;COPII-coated vesicle budding#GO:0090114;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into nucleus#GO:0051170 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;envelope#GO:0031975;nuclear pore#GO:0005643;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;nucleus#GO:0005634;intracellular vesicle#GO:0097708;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;nuclear protein-containing complex#GO:0140513 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013833.1|UniProtKB=W5N8V6 W5N8V6 PAK3 PTHR45832:SF11 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED SERINE_THREONINE-PROTEIN KINASE PAK 3 LEPOC|Ensembl=ENSLOCG00000004348.1|UniProtKB=W5M9Y8 W5M9Y8 PTHR15507:SF18 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN RLF nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017413.1|UniProtKB=W5NLK9 W5NLK9 PTHR22237:SF2 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 3 phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;beta-catenin binding#GO:0008013 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013913.1|UniProtKB=W5N942 W5N942 PTHR47266:SF33 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007492.1|UniProtKB=W5ML36 W5ML36 PTHR24034:SF137 EGF-LIKE DOMAIN-CONTAINING PROTEIN SI:DKEY-163F14.6 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000002402.1|UniProtKB=W5M356 W5M356 DCDC2B PTHR23004:SF10 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2B supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004408.1|UniProtKB=W5MA57 W5MA57 PTHR31259:SF3 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564 endosome#GO:0005768;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000010669.1|UniProtKB=W5MXF8 W5MXF8 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013326.1|UniProtKB=W5N715 W5N715 PTHR11205:SF19 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009008.1|UniProtKB=W5MRG5 W5MRG5 PTHR11003:SF57 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 13 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008554.1|UniProtKB=W5MPV0 W5MPV0 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002325.1|UniProtKB=W5M2X8 W5M2X8 PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;citrate transmembrane transporter activity#GO:0015137;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transmembrane transport#GO:1903825;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842;carboxylic acid transmembrane transport#GO:1905039 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008636.1|UniProtKB=W5MQ40 W5MQ40 PTHR10082:SF11 INTEGRIN BETA SUBUNIT INTEGRIN BETA-6 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000013943.1|UniProtKB=W5N983 W5N983 PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;receptor internalization#GO:0031623;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;localization#GO:0051179;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001105.1|UniProtKB=W5LYP3 W5LYP3 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000017975.1|UniProtKB=W5NN67 W5NN67 P2RY6 PTHR24231:SF16 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013323.1|UniProtKB=W5N714 W5N714 PTHR17388:SF2 SECRETOGRANIN III SECRETOGRANIN-3 localization#GO:0051179;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000011947.1|UniProtKB=W5N233 W5N233 PTHR24034:SF76 EGF-LIKE DOMAIN-CONTAINING PROTEIN COLLAGEN AND CALCIUM-BINDING EGF DOMAIN-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000010601.1|UniProtKB=W5MX81 W5MX81 PTHR24286:SF24 CYTOCHROME P450 26 LANOSTEROL 14-ALPHA DEMETHYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014941.1|UniProtKB=W5NCP0 W5NCP0 PTHR10687:SF7 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 2 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cytoplasmic vesicle membrane#GO:0030659 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002205.1|UniProtKB=W5M2H0 W5M2H0 PTHR11188:SF48 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 2 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006086.1|UniProtKB=W5MG46 W5MG46 PTHR47276:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 LEPOC|Ensembl=ENSLOCG00000004264.1|UniProtKB=W5M9P3 W5M9P3 SETX PTHR10887:SF495 DNA2/NAM7 HELICASE FAMILY HELICASE SENATAXIN ISOFORM X1-RELATED RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000007971.1|UniProtKB=W5MMS2 W5MMS2 PTHR23112:SF0 G PROTEIN-COUPLED RECEPTOR 157-RELATED TRANSMEMBRANE PROTEIN 116 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008573.1|UniProtKB=W5MPW6 W5MPW6 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000007617.1|UniProtKB=W5MLJ9 W5MLJ9 PTHR24020:SF14 COLLAGEN ALPHA MATRILIN-4 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000015038.1|UniProtKB=W5NCZ8 W5NCZ8 PTHR11064:SF9 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014904.1|UniProtKB=W5NCJ5 W5NCJ5 PTHR16231:SF4 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000014392.1|UniProtKB=W5NAR0 W5NAR0 PTHR31428:SF4 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011872.1|UniProtKB=W5N1U0 W5N1U0 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009558.1|UniProtKB=W5MTH2 W5MTH2 PTHR48034:SF1 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011010.1|UniProtKB=W5MYQ1 W5MYQ1 PTHR15615:SF108 FAMILY NOT NAMED PROTEIN CNPPD1 LEPOC|Ensembl=ENSLOCG00000000186.1|UniProtKB=W5LVQ3 W5LVQ3 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000010071.1|UniProtKB=W5MVA7 W5MVA7 MLANA PTHR15305:SF0 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 LEPOC|Ensembl=ENSLOCG00000004801.1|UniProtKB=W5MBK3 W5MBK3 PTHR11636:SF6 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009338.1|UniProtKB=W5MSN3 W5MSN3 PTHR24188:SF29 ANKYRIN REPEAT PROTEIN GH09064P LEPOC|Ensembl=ENSLOCG00000004040.1|UniProtKB=W5M8W5 W5M8W5 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58_P45 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003922.1|UniProtKB=W5M8H2 W5M8H2 PTHR14647:SF56 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;developmental process#GO:0032502;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;nervous system development#GO:0007399;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosphingolipid biosynthetic process#GO:0006688;multicellular organism development#GO:0007275;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;anatomical structure development#GO:0048856;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;multicellular organismal process#GO:0032501;cellular lipid metabolic process#GO:0044255;myelination#GO:0042552 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017912.1|UniProtKB=W5NN06 W5NN06 PTHR47399:SF1 TRANSMEMBRANE PROTEIN 121B TRANSMEMBRANE PROTEIN 121B LEPOC|Ensembl=ENSLOCG00000007945.1|UniProtKB=W5MMP3 W5MMP3 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004890.1|UniProtKB=W5MBX6 W5MBX6 PTHR11680:SF59 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 LEPOC|Ensembl=ENSLOCG00000015794.1|UniProtKB=W5NFN3 W5NFN3 PTHR24247:SF212 5-HYDROXYTRYPTAMINE RECEPTOR PARIETOPSIN signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007072.1|UniProtKB=W5MJK5 W5MJK5 PTHR10612:SF34 APOLIPOPROTEIN D APOLIPOPROTEIN D apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014780.1|UniProtKB=W5NC44 W5NC44 PTHR10316:SF41 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MAGI FAMILY MEMBER, X-LINKED A-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011961.1|UniProtKB=W5N252 W5N252 PTHR24099:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007728.1|UniProtKB=W5MLX3 W5MLX3 PTHR24329:SF340 HOMEOBOX PROTEIN ARISTALESS ARISTALESS RELATED HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009755.1|UniProtKB=W5MU53 W5MU53 PTHR11461:SF375 SERINE PROTEASE INHIBITOR, SERPIN THYROXINE-BINDING GLOBULIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000002327.1|UniProtKB=W5M2Y3 W5M2Y3 PTHR23316:SF8 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-7 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007018.1|UniProtKB=W5MJD4 W5MJD4 PTHR11633:SF4 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR D growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 LEPOC|Ensembl=ENSLOCG00000005704.1|UniProtKB=W5MES5 W5MES5 PTHR23011:SF43 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 LEPOC|Ensembl=ENSLOCG00000010557.1|UniProtKB=W5MX35 W5MX35 PTHR11941:SF44 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydratase#PC00120 LEPOC|Ensembl=ENSLOCG00000005580.1|UniProtKB=W5MEC5 W5MEC5 PTHR20863:SF28 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002129.1|UniProtKB=W5M266 W5M266 PTHR12209:SF0 NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT TP53RK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017866.1|UniProtKB=W5NMW0 W5NMW0 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011176.1|UniProtKB=W5MZC4 W5MZC4 PTHR22761:SF12 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016563.1|UniProtKB=W5NIK3 W5NIK3 CYB5R4 PTHR46237:SF1 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor#GO:0016653;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012404.1|UniProtKB=W5N3R3 W5N3R3 PTHR24240:SF153 OPSIN GREEN-SENSITIVE OPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003603.1|UniProtKB=W5M7B2 W5M7B2 PTHR45702:SF1 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 10 ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006433.1|UniProtKB=W5MHB0 W5MHB0 CCDC34 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000013157.1|UniProtKB=W5N6F0 W5N6F0 PTHR12668:SF4 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14C-RELATED regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016932.1|UniProtKB=W5NJX4 W5NJX4 PTHR24064:SF457 SOLUTE CARRIER FAMILY 22 MEMBER TRANSPORTER SVOPL-RELATED secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018282.1|UniProtKB=W5NP24 W5NP24 PTHR24233:SF6 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PLATELET-ACTIVATING FACTOR RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000010919.1|UniProtKB=W5MYD1 W5MYD1 PTHR19290:SF102 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000007497.1|UniProtKB=W5ML41 W5ML41 PTHR31774:SF1 PROTEIN SHISA-9-RELATED PROTEIN SHISA-9 regulation of cell communication#GO:0010646;regulation of transmembrane transport#GO:0034762;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of neuronal synaptic plasticity#GO:0048168;regulation of transporter activity#GO:0032409 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;cell projection membrane#GO:0031253;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002287.1|UniProtKB=W5M2T3 W5M2T3 PTHR10194:SF4 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 4-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 LEPOC|Ensembl=ENSLOCG00000016118.1|UniProtKB=W5NGV6 W5NGV6 PTHR23257:SF731 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004534.1|UniProtKB=W5MAW8 W5MAW8 PTHR21725:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR4 E3 UBIQUITIN-PROTEIN LIGASE UBR4 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006850.1|UniProtKB=W5MIS1 W5MIS1 PTHR23235:SF54 KRUEPPEL-LIKE TRANSCRIPTION FACTOR E3 SUMO-PROTEIN LIGASE EGR2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001625.1|UniProtKB=W5M0H6 W5M0H6 PTHR12911:SF23 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 envelope#GO:0031975;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015010.1|UniProtKB=W5NCX5 W5NCX5 AP3B2 PTHR11134:SF11 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-2 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;axo-dendritic transport#GO:0008088;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013349.1|UniProtKB=W5N744 W5N744 PTHR11947:SF15 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266 LEPOC|Ensembl=ENSLOCG00000007146.1|UniProtKB=W5MJU2 W5MJU2 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010443.1|UniProtKB=W5MWP9 W5MWP9 PTHR10061:SF0 S-FORMYLGLUTATHIONE HYDROLASE S-FORMYLGLUTATHIONE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007707.1|UniProtKB=W5MLU4 W5MLU4 PTHR15487:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein localization to nucleus#GO:0034504;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;protein localization to organelle#GO:0033365;positive regulation of biological process#GO:0048518;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000467.1|UniProtKB=W5LWK2 W5LWK2 PTHR44281:SF4 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG male gamete generation#GO:0048232;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;gamete generation#GO:0007276;centriole assembly#GO:0098534;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;organelle assembly#GO:0070925;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010370.1|UniProtKB=W5MWF1 W5MWF1 PTHR11494:SF8 CYTOTOXIC T-LYMPHOCYTE PROTEIN CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006232.1|UniProtKB=W5MGL4 W5MGL4 PTHR19433:SF72 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA CHAIN MC.7.G5-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004137.1|UniProtKB=W5M989 W5M989 PTHR24329:SF542 HOMEOBOX PROTEIN ARISTALESS DORSAL ROOT GANGLIA HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000006579.1|UniProtKB=W5MHU8 W5MHU8 PTHR11036:SF135 SEMAPHORIN SEMAPHORIN 4D ISOFORM X1-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of GTPase activity#GO:0043087;ossification#GO:0001503;positive regulation of locomotion#GO:0040017;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of hydrolase activity#GO:0051345;negative regulation of nitrogen compound metabolic process#GO:0051172;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;bone development#GO:0060348;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;regulation of biosynthetic process#GO:0009889;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular biosynthetic process#GO:0031326;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015227.1|UniProtKB=W5NDP9 W5NDP9 PTHR24123:SF71 ANKYRIN REPEAT-CONTAINING ANKYRIN 1, ERYTHROCYTIC A ISOFORM X1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004558.1|UniProtKB=W5MAR3 W5MAR3 PTHR24198:SF65 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 4 regulation of DNA-binding transcription factor activity#GO:0051090;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of NF-kappaB transcription factor activity#GO:0051092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018186.1|UniProtKB=W5NNS8 W5NNS8 PTHR36542:SF6 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREP cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016812.1|UniProtKB=W5NJG9 W5NJG9 PTHR11685:SF99 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144A ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016407.1|UniProtKB=W5NI02 W5NI02 PTHR36688:SF2 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009825.1|UniProtKB=W5MUF2 W5MUF2 PTHR10372:SF3 PLAKOPHILLIN-RELATED PLAKOPHILIN-1 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000015002.1|UniProtKB=W5NCW2 W5NCW2 PTHR22978:SF30 B-CELL TRANSLOCATION GENE PROTEIN BTG1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007919.1|UniProtKB=W5MMK5 W5MMK5 PTHR11038:SF16 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005547.1|UniProtKB=W5ME90 W5ME90 PTHR47633:SF1 IMMUNOGLOBULIN MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 LEPOC|Ensembl=ENSLOCG00000005214.1|UniProtKB=W5MD13 W5MD13 PTHR45684:SF6 RE74312P GTP-BINDING PROTEIN SAR1A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;positive regulation of protein transport#GO:0051222;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;positive regulation of establishment of protein localization#GO:1904951;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;positive regulation of protein localization#GO:1903829;regulation of establishment of protein localization#GO:0070201 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000008452.1|UniProtKB=W5MPH3 W5MPH3 PTHR44144:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016074.1|UniProtKB=W5NGP5 W5NGP5 PTHR45793:SF9 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>OTX#P06818 LEPOC|Ensembl=ENSLOCG00000005041.1|UniProtKB=W5MCH4 W5MCH4 PTHR43831:SF1 ISOBUTYRYL-COA DEHYDROGENASE ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005967.1|UniProtKB=W5MFQ9 W5MFQ9 WBP4 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002984.1|UniProtKB=W5M556 W5M556 PTHR11885:SF6 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016281.1|UniProtKB=W5NHH7 W5NHH7 PTHR12784:SF18 STEERIN NEURON NAVIGATOR 3 system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000009978.1|UniProtKB=W5MUZ8 W5MUZ8 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of proteolysis#GO:0030162;regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;biological regulation#GO:0065007;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of metabolic process#GO:0019222 LEPOC|Ensembl=ENSLOCG00000000047.1|UniProtKB=W5LV99 W5LV99 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000014819.1|UniProtKB=W5NC89 W5NC89 PTHR11683:SF17 MYELIN PROTEOLIPID DMALPHA1 structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;gliogenesis#GO:0042063;cellular component organization#GO:0016043;cellular process#GO:0009987;oligodendrocyte differentiation#GO:0048709;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;glial cell differentiation#GO:0010001;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;generation of neurons#GO:0048699;myelination#GO:0042552 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000015729.1|UniProtKB=W5NFF5 W5NFF5 PTHR24064:SF461 SOLUTE CARRIER FAMILY 22 MEMBER ORGANIC CATION TRANSPORTER 2 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic cation transport#GO:0015695;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005629.1|UniProtKB=W5MEK7 W5MEK7 PTHR11864:SF0 PRE-MRNA-PROCESSING PROTEIN PRP40 PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST) nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000008434.1|UniProtKB=W5MPG5 W5MPG5 PTHR21068:SF43 SPARTIN SPARTIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009475.1|UniProtKB=W5MT55 W5MT55 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011162.1|UniProtKB=W5MZA9 W5MZA9 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9 LEPOC|Ensembl=ENSLOCG00000000393.1|UniProtKB=W5LWC2 W5LWC2 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000008600.1|UniProtKB=W5MQ03 W5MQ03 PTHR15574:SF39 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 6 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016483.1|UniProtKB=W5NIB6 W5NIB6 PTHR21497:SF28 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000533.1|UniProtKB=W5LWT3 W5LWT3 PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000004086.1|UniProtKB=W5M915 W5M915 PTHR11723:SF4 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006553.1|UniProtKB=W5MHQ9 W5MHQ9 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000712.1|UniProtKB=W5LXD8 W5LXD8 PTHR12901:SF14 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000207.1|UniProtKB=W5LVS3 W5LVS3 PTHR46780:SF21 PROTEIN EVA-1 ADHESION G PROTEIN-COUPLED RECEPTOR L3-RELATED LEPOC|Ensembl=ENSLOCG00000000476.1|UniProtKB=W5LWL5 W5LWL5 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000089.1|UniProtKB=W5LVE2 W5LVE2 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER LEPOC|Ensembl=ENSLOCG00000007802.1|UniProtKB=W5MM57 W5MM57 MFAP2 PTHR16485:SF3 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 sensory organ morphogenesis#GO:0090596;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;eye morphogenesis#GO:0048592;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423;embryonic morphogenesis#GO:0048598 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016795.1|UniProtKB=W5NJE9 W5NJE9 PTHR45820:SF3 FI23527P1 CALCIUM_MANGANESE ANTIPORTER SLC30A10 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;response to stimulus#GO:0050896;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;response to toxic substance#GO:0009636;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009730.1|UniProtKB=W5MU21 W5MU21 PTHR12056:SF4 DNA-DIRECTED RNA POLYMERASES I, II, AND III DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000018250.1|UniProtKB=W5NNZ2 W5NNZ2 PTHR24366:SF46 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT NEURONAL 1 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007676.1|UniProtKB=W5MLR0 W5MLR0 PTHR45965:SF4 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 1 regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of cellular localization#GO:0060341;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of ERBB signaling pathway#GO:1901184;regulation of protein transport#GO:0051223;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007127.1|UniProtKB=W5MJR7 W5MJR7 PTHR11211:SF14 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011057.1|UniProtKB=W5MYX1 W5MYX1 PTHR22957:SF462 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22B nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003470.1|UniProtKB=W5M6W2 W5M6W2 PTHR13890:SF0 RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000502.1|UniProtKB=W5LWP5 W5LWP5 GJD4 PTHR11984:SF3 CONNEXIN GAP JUNCTION DELTA-4 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000016033.1|UniProtKB=W5NGI9 W5NGI9 PTHR31258:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 3 KERATINOCYTE-ASSOCIATED PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000010280.1|UniProtKB=W5MW66 W5MW66 PTHR48092:SF12 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001825.1|UniProtKB=W5M152 W5M152 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000914.1|UniProtKB=W5LY35 W5LY35 PTHR15750:SF4 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 2 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of anatomical structure morphogenesis#GO:0022603;biological regulation#GO:0065007;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017687.1|UniProtKB=W5NMD3 W5NMD3 PTHR40472:SF10 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 5 LEPOC|Ensembl=ENSLOCG00000003144.1|UniProtKB=W5M5Q1 W5M5Q1 PTHR16441:SF0 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893 LEPOC|Ensembl=ENSLOCG00000004746.1|UniProtKB=W5MBD1 W5MBD1 PTHR24383:SF12 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 618 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004367.1|UniProtKB=W5MA21 W5MA21 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 FATTY-ACID PEROXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016427.1|UniProtKB=W5NI30 W5NI30 PTHR15881:SF2 MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;regulation of multicellular organismal process#GO:0051239;regulation of mononuclear cell proliferation#GO:0032944;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of immune system process#GO:0002682;regulation of leukocyte proliferation#GO:0070663;regulation of lymphocyte activation#GO:0051249;regulation of B cell proliferation#GO:0030888 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002810.1|UniProtKB=W5M4J7 W5M4J7 PTHR21680:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017370.1|UniProtKB=W5NLG6 W5NLG6 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003824.1|UniProtKB=W5M861 W5M861 PTHR11216:SF123 EH DOMAIN SI:DKEY-98F17.5 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015408.1|UniProtKB=W5NEA9 W5NEA9 PTHR11388:SF99 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000500.1|UniProtKB=W5LWP3 W5LWP3 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000004559.1|UniProtKB=W5MAP6 W5MAP6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5-RELATED cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015850.1|UniProtKB=W5NFV4 W5NFV4 PTHR43146:SF1 CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000005829.1|UniProtKB=W5MF79 W5MF79 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009578.1|UniProtKB=W5MTJ5 W5MTJ5 PTHR43220:SF21 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41A LEPOC|Ensembl=ENSLOCG00000002981.1|UniProtKB=W5M554 W5M554 PTHR19960:SF12 TEKTIN TEKTIN-4 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000009553.1|UniProtKB=W5MTH0 W5MTH0 PTHR10663:SF388 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000336.1|UniProtKB=W5LW56 W5LW56 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED SI:CH211-113E8.5 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001704.1|UniProtKB=W5M0Q4 W5M0Q4 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 LEPOC|Ensembl=ENSLOCG00000016867.1|UniProtKB=W5NJP2 W5NJP2 PTHR12048:SF0 CCAAT-BINDING FACTOR-RELATED CCAAT_ENHANCER-BINDING PROTEIN ZETA membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009402.1|UniProtKB=W5MSW0 W5MSW0 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Ubc7#P01220;Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000009526.1|UniProtKB=W5MTD0 W5MTD0 PTHR12052:SF4 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4B nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001604.1|UniProtKB=W5M0G2 W5M0G2 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003200.1|UniProtKB=W5M5X1 W5M5X1 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005964.1|UniProtKB=W5MFP0 W5MFP0 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 16 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008621.1|UniProtKB=W5MQ19 W5MQ19 ZC3H3 PTHR46156:SF1 CCCH ZINGC FINGER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000006756.1|UniProtKB=W5MIF1 W5MIF1 PTHR12704:SF3 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005962.1|UniProtKB=W5MFP2 W5MFP2 PTHR10782:SF9 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS4 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like protein ligase activity#GO:0061659;SUMO ligase activity#GO:0061665;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein sumoylation#GO:0016925;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 LEPOC|Ensembl=ENSLOCG00000004001.1|UniProtKB=W5M8R4 W5M8R4 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011263.1|UniProtKB=W5MZN5 W5MZN5 PTHR10811:SF6 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of Notch signaling pathway#GO:0008593 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 LEPOC|Ensembl=ENSLOCG00000016343.1|UniProtKB=W5NHR7 W5NHR7 PTHR24329:SF359 HOMEOBOX PROTEIN ARISTALESS ALX HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005281.1|UniProtKB=W5MDC0 W5MDC0 PTHR13817:SF103 TITIN ROUNDABOUT GUIDANCE RECEPTOR 3 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005577.1|UniProtKB=W5MEE0 W5MEE0 PTHR11689:SF158 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009539.1|UniProtKB=W5MTE7 W5MTE7 PTHR21408:SF1 HOMEODOMAIN-ONLY PROTEIN HOMEODOMAIN-ONLY PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004762.1|UniProtKB=W5MBI0 W5MBI0 C1orf146 PTHR31408:SF2 HYPOTHETICAL PROTEIN LOC689986 PROTEIN SPO16 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;synaptonemal complex assembly#GO:0007130;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010449.1|UniProtKB=W5MWQ1 W5MWQ1 PTHR24418:SF227 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of immune response#GO:0050776;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Fer#P00469 LEPOC|Ensembl=ENSLOCG00000000097.1|UniProtKB=W5LVF4 W5LVF4 PTHR14140:SF2 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;primary metabolic process#GO:0044238;epigenetic regulation of gene expression#GO:0040029;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016853.1|UniProtKB=W5NJM4 W5NJM4 PARP11 PTHR45740:SF4 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003060.1|UniProtKB=W5M5D5 W5M5D5 PTHR14519:SF5 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009180.1|UniProtKB=W5MS39 W5MS39 PTHR12085:SF3 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015915.1|UniProtKB=W5NG36 W5NG36 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007204.1|UniProtKB=W5MK12 W5MK12 PTHR23067:SF13 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009734.1|UniProtKB=W5MU30 W5MU30 PTHR10824:SF38 ACYL-COENZYME A THIOESTERASE-RELATED ACOT1 THIOESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000006722.1|UniProtKB=W5MID2 W5MID2 PTHR45622:SF70 UBIQUITIN-PROTEIN LIGASE E3A-RELATED SECRETION-REGULATING GUANINE NUCLEOTIDE EXCHANGE FACTOR cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002469.1|UniProtKB=W5M3J4 W5M3J4 ABCA7 PTHR19229:SF49 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7 signaling receptor activity#GO:0038023;transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;phosphatidylcholine transporter activity#GO:0008525;molecular transducer activity#GO:0060089;phospholipid transporter activity#GO:0005548;cargo receptor activity#GO:0038024;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;cholesterol transport#GO:0030301;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;cholesterol efflux#GO:0033344;lipid transport#GO:0006869 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015298.1|UniProtKB=W5NDW3 W5NDW3 UTP14C PTHR14150:SF12 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014373.1|UniProtKB=W5NAP0 W5NAP0 PTHR25465:SF5 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002919.1|UniProtKB=W5M4X0 W5M4X0 PTHR18860:SF158 14-3-3 PROTEIN 14-3-3 PROTEIN GAMMA-1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 LEPOC|Ensembl=ENSLOCG00000006039.1|UniProtKB=W5MFY9 W5MFY9 PTHR11328:SF31 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 ISOFORM X1-RELATED localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003731.1|UniProtKB=W5M7S7 W5M7S7 PTHR15319:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;core promoter sequence-specific DNA binding#GO:0001046;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase I transcription regulatory region sequence-specific DNA binding#GO:0001163 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649 LEPOC|Ensembl=ENSLOCG00000015086.1|UniProtKB=W5ND57 W5ND57 PTHR21490:SF0 ENKURIN-RELATED ENKURIN protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000015343.1|UniProtKB=W5NE23 W5NE23 PTHR15228:SF20 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 25 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 negative regulation of biological process#GO:0048519;membrane organization#GO:0061024;negative regulation of intracellular signal transduction#GO:1902532;transport#GO:0006810;activation of GTPase activity#GO:0090630;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;supramolecular fiber organization#GO:0097435;regulation of signal transduction#GO:0009966;actin filament organization#GO:0007015;negative regulation of small GTPase mediated signal transduction#GO:0051058;regulation of hydrolase activity#GO:0051336;cytoskeleton organization#GO:0007010;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of GTPase activity#GO:0043087;phagocytosis#GO:0006909;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;negative regulation of signaling#GO:0023057;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;actin cytoskeleton organization#GO:0030036;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000011449.1|UniProtKB=W5N0B3 W5N0B3 PTHR11556:SF11 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;hexose biosynthetic process#GO:0019319;oligosaccharide biosynthetic process#GO:0009312;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008358.1|UniProtKB=W5MP61 W5MP61 PTHR19143:SF338 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN GAMMA CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Blood coagulation#P00011>Fibrinogen#P00406;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443 LEPOC|Ensembl=ENSLOCG00000013603.1|UniProtKB=W5N820 W5N820 PTHR18945:SF455 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;chloride transmembrane transporter activity#GO:0015108;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015153.1|UniProtKB=W5NDE7 W5NDE7 PTHR22845:SF5 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 p53 pathway#P00059>Apaf#G04703;Apoptosis signaling pathway#P00006>Apaf-1#P00301;FAS signaling pathway#P00020>Apaf1#P00597;Huntington disease#P00029>Apaf-1#P00768 LEPOC|Ensembl=ENSLOCG00000009100.1|UniProtKB=W5MRT9 W5MRT9 PTHR13713:SF94 SIALYLTRANSFERASE ST3 BETA-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE 5, LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017251.1|UniProtKB=W5NL30 W5NL30 PTHR13465:SF3 UPF0183 PROTEIN PROTEIN BROAD-MINDED organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 LEPOC|Ensembl=ENSLOCG00000011990.1|UniProtKB=W5N290 W5N290 PTHR45638:SF9 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ROD PHOTORECEPTOR SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;ligand-gated monoatomic cation channel activity#GO:0099094;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000007436.1|UniProtKB=W5MKW2 W5MKW2 PTHR12889:SF7 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;Notch signaling pathway#GO:0007219 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014545.1|UniProtKB=W5NB96 W5NB96 PTHR10075:SF108 BASIGIN RELATED NEUROPLASTIN cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012068.1|UniProtKB=W5N2I9 W5N2I9 PTHR24197:SF44 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54 LEPOC|Ensembl=ENSLOCG00000017515.1|UniProtKB=W5NLW1 W5NLW1 PTHR11711:SF137 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4D carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000001469.1|UniProtKB=W5LZX6 W5LZX6 MLKL PTHR23257:SF873 SERINE-THREONINE PROTEIN KINASE MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001405.1|UniProtKB=W5LZR2 W5LZR2 EIF5B PTHR43381:SF4 TRANSLATION INITIATION FACTOR IF-2-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 5B nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000272.1|UniProtKB=W5LVZ0 W5LVZ0 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014407.1|UniProtKB=W5NAS5 W5NAS5 PTHR45624:SF56 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic cation transport#GO:0015695;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 envelope#GO:0031975;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007407.1|UniProtKB=W5MKT1 W5MKT1 PTHR24072:SF262 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;postsynapse#GO:0098794;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane bounded cell projection#GO:0120025 small GTPase#PC00208 Ras Pathway#P04393>Cdc42#P04569 LEPOC|Ensembl=ENSLOCG00000017787.1|UniProtKB=W5NMN2 W5NMN2 PTHR13864:SF10 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000000777.1|UniProtKB=W5LXK2 W5LXK2 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016178.1|UniProtKB=W5NH27 W5NH27 PTHR10414:SF47 ETHANOLAMINEPHOSPHOTRANSFERASE ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010095.1|UniProtKB=W5MVE5 W5MVE5 RIC1 PTHR22746:SF10 RAB6A-GEF COMPLEX PARTNER PROTEIN 1 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045;Golgi membrane#GO:0000139 LEPOC|Ensembl=ENSLOCG00000014094.1|UniProtKB=W5N9Q6 W5N9Q6 FGD3 PTHR12673:SF14 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;filopodium assembly#GO:0046847;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014005.1|UniProtKB=W5N9F8 W5N9F8 PTHR11907:SF0 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 LEPOC|Ensembl=ENSLOCG00000014625.1|UniProtKB=W5NBI9 W5NBI9 PTHR13612:SF0 ENHANCER OF MRNA-DECAPPING PROTEIN 3 ENHANCER OF MRNA-DECAPPING PROTEIN 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;RNA decapping#GO:0110154;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;P-body assembly#GO:0033962;non-membrane-bounded organelle assembly#GO:0140694;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 LEPOC|Ensembl=ENSLOCG00000011508.1|UniProtKB=W5N0J6 W5N0J6 PTHR19229:SF34 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1 transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001262.1|UniProtKB=W5LZ83 W5LZ83 PTHR24390:SF230 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 362 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004267.1|UniProtKB=W5M9P4 W5M9P4 PTHR14248:SF32 CYCLIN Y, ISOFORM A CYCLIN-Y-LIKE PROTEIN 1 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004695.1|UniProtKB=W5MB74 W5MB74 PTHR22957:SF679 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN ECOTROPIC VIRAL INTEGRATION SITE 5 PROTEIN HOMOLOG nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009774.1|UniProtKB=W5MU83 W5MU83 PTHR11216:SF57 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;plasma membrane bounded cell projection organization#GO:0120036;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization#GO:0008104;organelle assembly#GO:0070925;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012606.1|UniProtKB=W5N4F6 W5N4F6 PTHR13680:SF34 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000007782.1|UniProtKB=W5MM38 W5MM38 PTHR10529:SF234 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;coated vesicle#GO:0030135;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002740.1|UniProtKB=W5M4G6 W5M4G6 PTHR21567:SF30 CLASP CLIP-ASSOCIATING PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;cell cortex#GO:0005938;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;basal part of cell#GO:0045178;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000007291.1|UniProtKB=W5MKC0 W5MKC0 PTHR48226:SF1 OS06G0326200 PROTEIN WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 1 actin filament-based process#GO:0030029;cellular process#GO:0009987;actin filament-based movement#GO:0030048 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014730.1|UniProtKB=W5NBX6 W5NBX6 IRAK1 PTHR24419:SF1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 histone modifying activity#GO:0140993;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to lipopolysaccharide#GO:0071222;positive regulation of molecular function#GO:0044093;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;positive regulation of NF-kappaB transcription factor activity#GO:0051092;mitotic cell cycle#GO:0000278;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;response to lipopolysaccharide#GO:0032496;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;response to interleukin-1#GO:0070555;cell cycle#GO:0007049;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAK1#P01343 LEPOC|Ensembl=ENSLOCG00000014957.1|UniProtKB=W5NCQ7 W5NCQ7 PTHR11879:SF36 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC 2 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;aspartate metabolic process#GO:0006531;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018234.1|UniProtKB=W5NNX6 W5NNX6 PTHR22966:SF61 2-AMINOETHANETHIOL DIOXYGENASE 2-AMINOETHANETHIOL DIOXYGENASE LEPOC|Ensembl=ENSLOCG00000016317.1|UniProtKB=W5NHN0 W5NHN0 PTHR23068:SF10 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3A cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;DNA methylation#GO:0006306;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;DNA modification#GO:0006304;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;DNA alkylation#GO:0006305;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000016382.1|UniProtKB=W5NHX2 W5NHX2 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014211.1|UniProtKB=W5NA45 W5NA45 PTHR33663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 LEPOC|Ensembl=ENSLOCG00000013580.1|UniProtKB=W5N7Y7 W5N7Y7 PTHR15999:SF2 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008517.1|UniProtKB=W5MPQ6 W5MPQ6 RSPH10B2 PTHR46613:SF1 RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED LEPOC|Ensembl=ENSLOCG00000008464.1|UniProtKB=W5MPJ3 W5MPJ3 PTHR12011:SF59 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012258.1|UniProtKB=W5N372 W5N372 PTHR12427:SF1 ATP SYNTHASE E CHAIN, MITOCHONDRIAL ATP SYNTHASE SUBUNIT E, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016421.1|UniProtKB=W5NI24 W5NI24 PTHR32122:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 LEPOC|Ensembl=ENSLOCG00000001621.1|UniProtKB=W5M0G3 W5M0G3 PTHR43389:SF1 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, KIDNEY ISOFORM inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014766.1|UniProtKB=W5NC21 W5NC21 PLP2 PTHR22776:SF4 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEOLIPID PROTEIN 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007719.1|UniProtKB=W5MLW5 W5MLW5 PTHR24193:SF86 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009438.1|UniProtKB=W5MT17 W5MT17 PTHR46806:SF3 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;wound healing#GO:0042060;response to stress#GO:0006950;response to wounding#GO:0009611 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007153.1|UniProtKB=W5MJU9 W5MJU9 LRRIQ4 PTHR45752:SF187 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010917.1|UniProtKB=W5MYD0 W5MYD0 PTHR16154:SF22 NEURABIN NEURABIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 signal transduction#GO:0007165;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;cell projection organization#GO:0030030;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000017895.1|UniProtKB=W5NMY9 W5NMY9 PTHR11521:SF23 TROPONIN T SLOW TROPONIN T cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;circulatory system process#GO:0003013;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle contraction#GO:0006941;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000001769.1|UniProtKB=W5M0Z6 W5M0Z6 PTHR46792:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;positive regulation of cell-substrate adhesion#GO:0010811;external encapsulating structure organization#GO:0045229;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular component organization#GO:0016043;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;extracellular matrix organization#GO:0030198;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cellular process#GO:0048522 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;basement membrane#GO:0005604 LEPOC|Ensembl=ENSLOCG00000008019.1|UniProtKB=W5MMY0 W5MMY0 PTHR10559:SF18 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN II LEPOC|Ensembl=ENSLOCG00000001257.1|UniProtKB=W5LZ71 W5LZ71 PTHR45640:SF14 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN A CHAIN protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;developmental process#GO:0032502;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;visual system development#GO:0150063;sensory system development#GO:0048880;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;response to heat#GO:0009408;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;lens development in camera-type eye#GO:0002088;response to temperature stimulus#GO:0009266;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;sensory organ development#GO:0007423 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000003985.1|UniProtKB=W5M8Q2 W5M8Q2 PTHR12533:SF10 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;calcineurin-mediated signaling#GO:0097720;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 LEPOC|Ensembl=ENSLOCG00000016878.1|UniProtKB=W5NJQ3 W5NJQ3 CILK1 PTHR24055:SF260 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE ICK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;signal transduction#GO:0007165;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005609.1|UniProtKB=W5MEG2 W5MEG2 PTHR11742:SF28 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IC hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002335.1|UniProtKB=W5M2X7 W5M2X7 CXorf38 PTHR35083:SF2 RGD1565685 PROTEIN CHROMOSOME 17 CXORF38 HOMOLOG LEPOC|Ensembl=ENSLOCG00000004804.1|UniProtKB=W5MBL1 W5MBL1 dis3l2 PTHR23355:SF9 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000014050.1|UniProtKB=W5N9K8 W5N9K8 PTHR44019:SF17 WD REPEAT-CONTAINING PROTEIN 55 F-BOX_WD REPEAT-CONTAINING PROTEIN 12 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000001456.1|UniProtKB=W5LZV9 W5LZV9 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4-LIKE ISOFORM X1 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000005828.1|UniProtKB=W5MF80 W5MF80 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000018150.1|UniProtKB=W5NNP2 W5NNP2 B3GNT4 PTHR11214:SF368 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009096.1|UniProtKB=W5MRT2 W5MRT2 SLCO4C1 PTHR11388:SF160 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015019.1|UniProtKB=W5NCY1 W5NCY1 PTHR11245:SF1 STANNIOCALCIN STANNIOCALCIN-1 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000006463.1|UniProtKB=W5MHE9 W5MHE9 BBOX1 PTHR10696:SF33 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000006236.1|UniProtKB=W5MGM3 W5MGM3 SLC39A13 PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009052.1|UniProtKB=W5MRM2 W5MRM2 PTHR19972:SF15 CALBINDIN SECRETAGOGIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;regulation of cell communication#GO:0010646;calcium ion homeostasis#GO:0055074;regulation of signaling#GO:0023051;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;regulation of synaptic plasticity#GO:0048167;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;intracellular monoatomic ion homeostasis#GO:0006873 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cytosol#GO:0005829;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002771.1|UniProtKB=W5M4F5 W5M4F5 PTHR15729:SF3 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 31 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cell leading edge#GO:0031252;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009114.1|UniProtKB=W5MRV6 W5MRV6 CCN3 PTHR11348:SF8 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 3 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell adhesion#GO:0007155;cell communication#GO:0007154;skeletal system development#GO:0001501;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;system development#GO:0048731;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;positive regulation of biological process#GO:0048518;signaling#GO:0023052 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000009649.1|UniProtKB=W5MTT3 W5MTT3 PTHR24068:SF159 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 T ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000015990.1|UniProtKB=W5NGC8 W5NGC8 PTHR24366:SF123 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT-CONTAINING PROTEIN 17 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000012384.1|UniProtKB=W5N3N9 W5N3N9 PTHR18945:SF218 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002316.1|UniProtKB=W5M2V1 W5M2V1 PTHR10993:SF7 OCTANOYLTRANSFERASE LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 LEPOC|Ensembl=ENSLOCG00000017552.1|UniProtKB=W5NLZ8 W5NLZ8 PTHR19290:SF82 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000006474.1|UniProtKB=W5MHG6 W5MHG6 PTHR11879:SF22 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213;Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 LEPOC|Ensembl=ENSLOCG00000006366.1|UniProtKB=W5MH22 W5MH22 PTHR31450:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER TYPE III ENDOSOME MEMBRANE PROTEIN TEMP LEPOC|Ensembl=ENSLOCG00000016910.1|UniProtKB=W5NJU9 W5NJU9 PTHR42738:SF16 HYDROXYMETHYLGLUTARYL-COA LYASE 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE, CYTOPLASMIC lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;branched-chain amino acid metabolic process#GO:0009081;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000002965.1|UniProtKB=W5M533 W5M533 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008824.1|UniProtKB=W5MQT3 W5MQT3 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012140.1|UniProtKB=W5N2S3 W5N2S3 PTHR22618:SF2 PROTEIN O-MANNOSE KINASE PROTEIN O-MANNOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate phosphorylation#GO:0046835;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003658.1|UniProtKB=W5M7I3 W5M7I3 PTHR11987:SF36 ALPHA-2,8-SIALYLTRANSFERASE SIA-ALPHA-2,3-GAL-BETA-1,4-GLCNAC-R:ALPHA 2,8-SIALYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012457.1|UniProtKB=W5N3X8 W5N3X8 PTHR22792:SF51 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005585.1|UniProtKB=W5MED3 W5MED3 PTHR47266:SF32 ENDONUCLEASE-RELATED ZGC:113436 LEPOC|Ensembl=ENSLOCG00000013907.1|UniProtKB=W5N937 W5N937 PTHR14659:SF1 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 LEPOC|Ensembl=ENSLOCG00000014268.1|UniProtKB=W5NAA5 W5NAA5 PTHR45817:SF8 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009426.1|UniProtKB=W5MSZ2 W5MSZ2 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000008436.1|UniProtKB=W5MPF1 W5MPF1 PTHR12266:SF0 NA+/CA2+ K+ INDEPENDENT EXCHANGER MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001565.1|UniProtKB=W5M077 W5M077 ASTE1 PTHR15665:SF1 ASTEROID PROTEIN PROTEIN ASTEROID HOMOLOG 1 LEPOC|Ensembl=ENSLOCG00000001358.1|UniProtKB=W5LZI2 W5LZI2 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A INNER CENTROMERE PROTEIN A-LIKE ISOFORM X1-RELATED regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011444.1|UniProtKB=W5N0A6 W5N0A6 KLHDC2 PTHR46228:SF3 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000637.1|UniProtKB=W5LX48 W5LX48 PTHR11471:SF23 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>TNF#P00259;Wnt signaling pathway#P00057>NFAT Target Genes#G01559 LEPOC|Ensembl=ENSLOCG00000009126.1|UniProtKB=W5MRW5 W5MRW5 PTHR33861:SF4 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC positive regulation of gene expression#GO:0010628;male gamete generation#GO:0048232;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;male meiotic nuclear division#GO:0007140;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;cellular process involved in reproduction in multicellular organism#GO:0022412;cell cycle process#GO:0022402;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;meiotic cell cycle process#GO:1903046;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;multicellular organism reproduction#GO:0032504;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;meiotic nuclear division#GO:0140013;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012975.1|UniProtKB=W5N5S0 W5N5S0 PTHR12619:SF20 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000007950.1|UniProtKB=W5MMP9 W5MMP9 PTHR14913:SF0 TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 receptor complex#GO:0043235;protein-containing complex#GO:0032991 Apoptosis signaling pathway#P00006>TRADD#P00319 LEPOC|Ensembl=ENSLOCG00000014687.1|UniProtKB=W5NBS1 W5NBS1 PTHR23065:SF51 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009728.1|UniProtKB=W5MU19 W5MU19 CD247 PTHR10035:SF2 T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>TCR zeta#P01296 LEPOC|Ensembl=ENSLOCG00000016486.1|UniProtKB=W5NIA7 W5NIA7 PTHR22969:SF14 IKB KINASE SERINE_THREONINE-PROTEIN KINASE TBK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>TBK1#P01361 LEPOC|Ensembl=ENSLOCG00000016716.1|UniProtKB=W5NJ43 W5NJ43 PTHR17008:SF1 MEIOSIS-EXPRESSED GENE 1 PROTEIN MEIOSIS EXPRESSED GENE 1 PROTEIN HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011220.1|UniProtKB=W5MZH3 W5MZH3 PTHR10768:SF0 60S RIBOSOMAL PROTEIN L37 RIBOSOMAL PROTEIN L37 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015851.1|UniProtKB=W5NFV9 W5NFV9 PTHR11562:SF30 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A3-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;response to stimulus#GO:0050896;metal ion transport#GO:0030001;response to chemical#GO:0042221;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001301.1|UniProtKB=W5LZB9 W5LZB9 PTHR24391:SF11 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006613.1|UniProtKB=W5MHY5 W5MHY5 PTHR10410:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED MPN DOMAIN-CONTAINING PROTEIN metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;BRCA1-A complex#GO:0070531;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000002677.1|UniProtKB=W5M446 W5M446 PTHR10157:SF29 DOPAMINE BETA HYDROXYLASE RELATED DOPAMINE BETA-HYDROXYLASE cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 organic hydroxy compound metabolic process#GO:1901615;cellular aromatic compound metabolic process#GO:0006725;amine metabolic process#GO:0009308;alcohol biosynthetic process#GO:0046165;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;catecholamine metabolic process#GO:0006584;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;extracellular region#GO:0005576;secretory granule#GO:0030141;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 hydroxylase#PC00122 Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063;Dopamine receptor mediated signaling pathway#P05912>DBH#P05955 LEPOC|Ensembl=ENSLOCG00000010509.1|UniProtKB=W5MWX0 W5MWX0 PTHR46361:SF5 ELECTRON CARRIER/ PROTEIN DISULFIDE OXIDOREDUCTASE DEP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001416.1|UniProtKB=W5LZQ5 W5LZQ5 PTHR11819:SF151 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003882.1|UniProtKB=W5M8C5 W5M8C5 PTHR24291:SF3 CYTOCHROME P450 FAMILY 4 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603;Vitamin D metabolism and pathway#P04396>25-Hydroxylase#P04601 LEPOC|Ensembl=ENSLOCG00000002132.1|UniProtKB=W5M284 W5M284 PTHR23280:SF8 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 3 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000000882.1|UniProtKB=W5LXX9 W5LXX9 PTHR11662:SF284 SOLUTE CARRIER FAMILY 17 SMALL INTESTINE URATE EXPORTER-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006207.1|UniProtKB=W5MGJ0 W5MGJ0 SLC35E2B PTHR11132:SF521 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E2A-RELATED secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014430.1|UniProtKB=W5NAU9 W5NAU9 PTHR47410:SF3 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;activation of immune response#GO:0002253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;regulation of molecular function#GO:0065009;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;canonical NF-kappaB signal transduction#GO:0007249;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;positive regulation of macromolecule metabolic process#GO:0010604;defense response to symbiont#GO:0140546;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;signal transduction#GO:0007165;positive regulation of molecular function#GO:0044093;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of cytokine production#GO:0001817;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000008749.1|UniProtKB=W5MQK8 W5MQK8 USP24 PTHR24006:SF729 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 24 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012970.1|UniProtKB=W5N5R7 W5N5R7 PTHR13779:SF7 WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER ATPASE WRNIP1 ATP-dependent activity, acting on DNA#GO:0008094;molecular function activator activity#GO:0140677;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006324.1|UniProtKB=W5MGY5 W5MGY5 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000004936.1|UniProtKB=W5MC29 W5MC29 NDUFA13 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006187.1|UniProtKB=W5MGI5 W5MGI5 PTHR11206:SF363 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012607.1|UniProtKB=W5N4G4 W5N4G4 PTHR10286:SF50 INORGANIC PYROPHOSPHATASE INORGANIC DIPHOSPHATASE hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 pyrophosphatase#PC00196 LEPOC|Ensembl=ENSLOCG00000007394.1|UniProtKB=W5MKR9 W5MKR9 PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;chromatin binding#GO:0003682;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098 regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of autophagy#GO:0010506;regulation of signaling#GO:0023051;regulation of cellular catabolic process#GO:0031329;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008547.1|UniProtKB=W5MPT5 W5MPT5 PTHR22792:SF71 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 6 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015374.1|UniProtKB=W5NE59 W5NE59 PTHR21485:SF3 HAD SUPERFAMILY MEMBERS CMAS AND KDSC N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000015084.1|UniProtKB=W5ND56 W5ND56 PTHR14009:SF7 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN LETM2, MITOCHONDRIAL intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002149.1|UniProtKB=W5M292 W5M292 PTHR23322:SF28 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010639.1|UniProtKB=W5MXB8 W5MXB8 PTHR15012:SF37 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015987.1|UniProtKB=W5NGC9 W5NGC9 PTHR24115:SF400 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF16B cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017993.1|UniProtKB=W5NN85 W5NN85 PTHR20855:SF22 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;response to steroid hormone#GO:0048545 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012264.1|UniProtKB=W5N394 W5N394 RASGRP1 PTHR23113:SF174 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 LEPOC|Ensembl=ENSLOCG00000003945.1|UniProtKB=W5M8K4 W5M8K4 PTHR24041:SF30 MUCIN MUCIN-3A cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012733.1|UniProtKB=W5N4W6 W5N4W6 PTHR11699:SF209 ALDEHYDE DEHYDROGENASE-RELATED RETINALDEHYDE DEHYDROGENASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000005879.1|UniProtKB=W5MFE0 W5MFE0 PTHR36542:SF8 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013440.1|UniProtKB=W5N7G2 W5N7G2 PTHR45659:SF2 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004233.1|UniProtKB=W5M9K4 W5M9K4 PTHR15623:SF11 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016679.1|UniProtKB=W5NIZ8 W5NIZ8 PTHR24073:SF269 DRAB5-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 27 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 LEPOC|Ensembl=ENSLOCG00000002615.1|UniProtKB=W5M3W8 W5M3W8 PTHR11767:SF52 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 LEPOC|Ensembl=ENSLOCG00000008166.1|UniProtKB=W5MNF2 W5MNF2 PTHR11028:SF0 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 regulation of intracellular pH#GO:0051453;cellular localization#GO:0051641;vacuolar transport#GO:0007034;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013723.1|UniProtKB=W5N8G4 W5N8G4 PTHR22437:SF2 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006844.1|UniProtKB=W5MIR7 W5MIR7 PTHR23411:SF18 TAPASIN TAPASIN-RELATED PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;immune system process#GO:0002376;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;antigen processing and presentation#GO:0019882;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008553.1|UniProtKB=W5MPU5 W5MPU5 PTHR16320:SF9 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELIN PHOSPHODIESTERASE 5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016053.1|UniProtKB=W5NGL9 W5NGL9 PTHR12098:SF4 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005782.1|UniProtKB=W5MF23 W5MF23 PTHR15427:SF29 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000682.1|UniProtKB=W5LX95 W5LX95 PTHR45598:SF1 PROTEIN CBG11839-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010567.1|UniProtKB=W5MX39 W5MX39 PTHR45831:SF1 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN BETA localization within membrane#GO:0051668;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016655.1|UniProtKB=W5NIW6 W5NIW6 PTHR21208:SF1 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009296.1|UniProtKB=W5MSI5 W5MSI5 PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017884.1|UniProtKB=W5NMX8 W5NMX8 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005969.1|UniProtKB=W5MFT0 W5MFT0 NPHP4 PTHR31043:SF3 NEPHROCYSTIN-4 NEPHROCYSTIN-4 LEPOC|Ensembl=ENSLOCG00000000582.1|UniProtKB=W5LWY7 W5LWY7 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014364.1|UniProtKB=W5NAM5 W5NAM5 PTHR12219:SF17 NADH-UBIQUINONE OXIDOREDUCTASE WD REPEAT-CONTAINING PROTEIN 93 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010392.1|UniProtKB=W5MWI4 W5MWI4 PTHR18867:SF12 RAD50 DNA REPAIR PROTEIN RAD50 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded telomeric DNA binding#GO:0043047;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;double-stranded DNA binding#GO:0003690 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;telomere maintenance via telomere lengthening#GO:0010833;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;DNA duplex unwinding#GO:0032508;mitotic recombination#GO:0006312;reproductive process#GO:0022414;telomere maintenance via telomerase#GO:0007004;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;sexual reproduction#GO:0019953;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000007610.1|UniProtKB=W5MLH4 W5MLH4 PTHR19969:SF16 SH2-SH3 ADAPTOR PROTEIN-RELATED CYTOPLASMIC PROTEIN NCK1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of translational initiation#GO:0006446;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;positive regulation of translation#GO:0045727;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to endoplasmic reticulum stress#GO:0034976;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of cell communication#GO:0010647;negative regulation of signal transduction#GO:0009968;regulation of translation#GO:0006417;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of amide metabolic process#GO:0034248;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cell migration#GO:0016477 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Nck#P00215;PDGF signaling pathway#P00047>Nck#P01147;PDGF signaling pathway#P00047>Grb2#P01148;T cell activation#P00053>nck#P01314 LEPOC|Ensembl=ENSLOCG00000011025.1|UniProtKB=W5MYS5 W5MYS5 PTHR13780:SF31 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000007186.1|UniProtKB=W5MJZ2 W5MJZ2 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;enzyme regulator activity#GO:0030234 response to external biotic stimulus#GO:0043207;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;detection of stimulus#GO:0051606;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;negative regulation of nitrogen compound metabolic process#GO:0051172;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000010726.1|UniProtKB=W5MXP1 W5MXP1 PTHR46730:SF2 POLYCYSTIN-1 POLYCYSTIN-1 ISOFORM X1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008840.1|UniProtKB=W5MQV1 W5MQV1 PTHR15706:SF10 SH3 MULTIPLE DOMAIN NADPH OXIDASE ORGANIZER 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016328.1|UniProtKB=W5NHP6 W5NHP6 PTHR14454:SF5 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000007152.1|UniProtKB=W5MJY3 W5MJY3 PTHR24223:SF339 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 6 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009877.1|UniProtKB=W5MUL1 W5MUL1 PTHR11454:SF9 INSULIN/INSULIN GROWTH FACTOR INSULIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 LEPOC|Ensembl=ENSLOCG00000005189.1|UniProtKB=W5MCY8 W5MCY8 PTHR46319:SF1 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 16 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 TGF-beta signaling pathway#P00052>SARA#P01281 LEPOC|Ensembl=ENSLOCG00000017595.1|UniProtKB=W5NM41 W5NM41 PTHR16121:SF2 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017280.1|UniProtKB=W5NL65 W5NL65 PTHR43981:SF4 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL-LIKE lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007528.1|UniProtKB=W5ML71 W5ML71 PTHR15186:SF4 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of programmed cell death#GO:0043067 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000015914.1|UniProtKB=W5NG37 W5NG37 PTHR22878:SF69 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED DYNEIN HEAVY CHAIN LEPOC|Ensembl=ENSLOCG00000009065.1|UniProtKB=W5MRQ9 W5MRQ9 PTHR23083:SF365 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7B lipid metabolic process#GO:0006629;cellular localization#GO:0051641;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007119.1|UniProtKB=W5MJR1 W5MJR1 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN LEPOC|Ensembl=ENSLOCG00000018063.1|UniProtKB=W5NNF5 W5NNF5 PTHR28615:SF2 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA2 protein kinase regulator activity#GO:0019887;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;protein kinase binding#GO:0019901;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase binding#GO:0019900 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000258.1|UniProtKB=W5LVX6 W5LVX6 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 LEPOC|Ensembl=ENSLOCG00000011714.1|UniProtKB=W5N193 W5N193 PTHR46251:SF4 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3A regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522 LEPOC|Ensembl=ENSLOCG00000002450.1|UniProtKB=W5M3C5 W5M3C5 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004036.1|UniProtKB=W5M8Y7 W5M8Y7 PTHR43377:SF2 BILIVERDIN REDUCTASE A BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00560)-RELATED dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005254.1|UniProtKB=W5MD83 W5MD83 PTHR23113:SF24 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006864.1|UniProtKB=W5MIU3 W5MIU3 PTHR25465:SF5 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005333.1|UniProtKB=W5MDG8 W5MDG8 PTHR10845:SF145 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 19 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000017683.1|UniProtKB=W5NMC9 W5NMC9 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;U6 snRNP#GO:0005688;organelle lumen#GO:0043233;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013827.1|UniProtKB=W5N8U4 W5N8U4 DENND4A PTHR12296:SF16 DENN DOMAIN-CONTAINING PROTEIN 4 C-MYC PROMOTER-BINDING PROTEIN regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016350.1|UniProtKB=W5NHT3 W5NHT3 C12orf29 PTHR31219:SF2 CHROMOSOME 28 C12ORF29 HOMOLOG RNA LIGASE 1 LEPOC|Ensembl=ENSLOCG00000013301.1|UniProtKB=W5N6Y2 W5N6Y2 TAC1 PTHR11250:SF5 TACHYKININ PROTACHYKININ-1-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000003993.1|UniProtKB=W5M8R9 W5M8R9 PTHR11675:SF38 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 17 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002372.1|UniProtKB=W5M323 W5M323 PTHR12533:SF4 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;calcineurin-mediated signaling#GO:0097720;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;CCKR signaling map#P06959>NFAT1#P07176;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367 LEPOC|Ensembl=ENSLOCG00000011874.1|UniProtKB=W5N1V1 W5N1V1 PTHR31915:SF8 SKICH DOMAIN-CONTAINING PROTEIN TAX1-BINDING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010794.1|UniProtKB=W5MXW9 W5MXW9 RMND5A PTHR12170:SF5 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5A transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002918.1|UniProtKB=W5M4Z3 W5M4Z3 PTHR22829:SF7 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of hydrolase activity#GO:0051336;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010405.1|UniProtKB=W5MWK1 W5MWK1 PTHR15036:SF46 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 5 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011269.1|UniProtKB=W5MZN9 W5MZN9 PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018071.1|UniProtKB=W5NNG3 W5NNG3 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000575.1|UniProtKB=W5LWX9 W5LWX9 PTHR31046:SF4 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121-LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000005275.1|UniProtKB=W5MD99 W5MD99 PTHR11937:SF150 ACTIN ACTSB PROTEIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000015307.1|UniProtKB=W5NDX6 W5NDX6 PTHR46090:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP RIBOSYLATION FACTOR LIKE GTPASE 13A non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;localization within membrane#GO:0051668;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 bounding membrane of organelle#GO:0098588;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015647.1|UniProtKB=W5NF53 W5NF53 PTHR24136:SF53 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX CONTAINING 13 positive regulation of nitrogen compound metabolic process#GO:0051173;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000014826.1|UniProtKB=W5NCA0 W5NCA0 PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 LEPOC|Ensembl=ENSLOCG00000017387.1|UniProtKB=W5NLI3 W5NLI3 PTHR24231:SF25 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001821.1|UniProtKB=W5M160 W5M160 PTHR11947:SF39 PYRUVATE DEHYDROGENASE KINASE PROTEIN-SERINE_THREONINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014445.1|UniProtKB=W5NAX0 W5NAX0 PTHR11581:SF0 30S/40S RIBOSOMAL PROTEIN S4 SMALL RIBOSOMAL SUBUNIT PROTEIN ES4 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011527.1|UniProtKB=W5N0K5 W5N0K5 PTHR19308:SF2 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017984.1|UniProtKB=W5NN76 W5NN76 PTHR16155:SF18 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004987.1|UniProtKB=W5MC92 W5MC92 PTHR15044:SF0 NEUROPEPTIDE FF PRO-FMRFAMIDE-RELATED NEUROPEPTIDE FF LEPOC|Ensembl=ENSLOCG00000001005.1|UniProtKB=W5LYC8 W5LYC8 PTHR19964:SF35 MULTIPLE PDZ DOMAIN PROTEIN PDZ DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014872.1|UniProtKB=W5NCF7 W5NCF7 PTHR10224:SF11 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL ES1 PROTEIN HOMOLOG, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000016546.1|UniProtKB=W5NIH4 W5NIH4 PTHR24034:SF94 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-7 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000007697.1|UniProtKB=W5MLZ6 W5MLZ6 PTHR45653:SF1 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;syncytium formation by plasma membrane fusion#GO:0000768;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;syncytium formation#GO:0006949;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Integrin signalling pathway#P00034>Dock180#P00930 LEPOC|Ensembl=ENSLOCG00000009555.1|UniProtKB=W5MTG9 W5MTG9 PTHR12277:SF48 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;regulation of synapse structure or activity#GO:0050803;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of postsynapse organization#GO:0099175;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000344.1|UniProtKB=W5LW69 W5LW69 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013726.1|UniProtKB=W5N8H1 W5N8H1 PTHR23215:SF0 ZINC FINGER PROTEIN 207 BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000438.1|UniProtKB=W5LWH4 W5LWH4 PTHR48051:SF55 FAMILY NOT NAMED MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002127.1|UniProtKB=W5M267 W5M267 PTHR22750:SF20 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003136.1|UniProtKB=W5M5R7 W5M5R7 PTHR11781:SF22 IODOTHYRONINE DEIODINASE TYPE I IODOTHYRONINE DEIODINASE metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005174.1|UniProtKB=W5MCX6 W5MCX6 PTHR45620:SF4 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007735.1|UniProtKB=W5MLX9 W5MLX9 PTHR24404:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN EOS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012899.1|UniProtKB=W5N5G6 W5N5G6 PTHR14167:SF45 SH3 DOMAIN-CONTAINING ENDOPHILIN-A3 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;protein-containing complex disassembly#GO:0032984;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>SH3GL3#P00813 LEPOC|Ensembl=ENSLOCG00000012454.1|UniProtKB=W5N3X2 W5N3X2 AMZ2 PTHR32205:SF5 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-2 LEPOC|Ensembl=ENSLOCG00000010134.1|UniProtKB=W5MVJ5 W5MVJ5 PTHR21274:SF2 MECKELIN MECKELIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000014923.1|UniProtKB=W5NCL7 W5NCL7 PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004386.1|UniProtKB=W5MA55 W5MA55 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010566.1|UniProtKB=W5MX37 W5MX37 PTHR21141:SF5 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002628.1|UniProtKB=W5M416 W5M416 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006409.1|UniProtKB=W5MH88 W5MH88 PTHR10131:SF96 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 1 protein binding#GO:0005515;tumor necrosis factor receptor binding#GO:0005164;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of cell communication#GO:0010646;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of NF-kappaB transcription factor activity#GO:0051092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015011.1|UniProtKB=W5NCX0 W5NCX0 PTHR19860:SF18 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DUF4062 DOMAIN-CONTAINING PROTEIN intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000007548.1|UniProtKB=W5MLB1 W5MLB1 AMOTL1 PTHR14826:SF12 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 1 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of cell motility#GO:2000145;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;ameboidal-type cell migration#GO:0001667;cellular component organization#GO:0016043;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;hippo signaling#GO:0035329;angiogenesis#GO:0001525;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;tight junction#GO:0070160;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000003359.1|UniProtKB=W5M6G2 W5M6G2 PTHR24346:SF29 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE NIM1-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003013.1|UniProtKB=W5M588 W5M588 PTHR31879:SF2 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteolysis#GO:0045862;regulation of proteasomal protein catabolic process#GO:0061136;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000000894.1|UniProtKB=W5LXY6 W5LXY6 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016159.1|UniProtKB=W5NH02 W5NH02 PTHR15160:SF9 VON HIPPEL-LINDAU PROTEIN ZGC:194223 PROTEIN protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003830.1|UniProtKB=W5M8E2 W5M8E2 PTHR24123:SF124 ANKYRIN REPEAT-CONTAINING TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001384.1|UniProtKB=W5LZM4 W5LZM4 PTHR11771:SF161 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15B oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017647.1|UniProtKB=W5NM93 W5NM93 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017088.1|UniProtKB=W5NKF9 W5NKF9 PTHR18937:SF147 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1B nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;cohesin complex#GO:0008278;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002183.1|UniProtKB=W5M2G4 W5M2G4 PTHR43184:SF9 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A2 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;inorganic anion transport#GO:0015698 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013942.1|UniProtKB=W5N980 W5N980 PTHR22883:SF207 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC2 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007736.1|UniProtKB=W5MLY2 W5MLY2 PTHR38663:SF1 FAMILY NOT NAMED L-ORNITHINE N(5)-MONOOXYGENASE LEPOC|Ensembl=ENSLOCG00000017022.1|UniProtKB=W5NK81 W5NK81 PTHR13255:SF0 ATAXIN-10 ATAXIN-10 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016985.1|UniProtKB=W5NK37 W5NK37 PTHR24064:SF454 SOLUTE CARRIER FAMILY 22 MEMBER SI:DKEY-119M7.4 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002700.1|UniProtKB=W5M492 W5M492 PTHR12771:SF8 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 2 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 LEPOC|Ensembl=ENSLOCG00000003155.1|UniProtKB=W5M5R3 W5M5R3 VMAC PTHR34707:SF1 VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN LEPOC|Ensembl=ENSLOCG00000008228.1|UniProtKB=W5MNN2 W5MNN2 PTHR14281:SF0 KINETOCHORE PROTEIN SPC25-RELATED KINETOCHORE PROTEIN SPC25 cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;outer kinetochore#GO:0000940;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome#GO:0000793;condensed chromosome, centromeric region#GO:0000779;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010536.1|UniProtKB=W5MX13 W5MX13 PTHR10924:SF3 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED HEME TRANSPORTER FLVCR2 tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014188.1|UniProtKB=W5NA19 W5NA19 PTHR14217:SF1 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001840.1|UniProtKB=W5M182 W5M182 PEMT PTHR15458:SF5 PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004853.1|UniProtKB=W5MBS5 W5MBS5 BRDT PTHR22880:SF143 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 4 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000639.1|UniProtKB=W5LX49 W5LX49 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001893.1|UniProtKB=W5M1D9 W5M1D9 PTHR46385:SF1 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010550.1|UniProtKB=W5MX17 W5MX17 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018246.1|UniProtKB=W5NNY8 W5NNY8 PTHR24240:SF15 OPSIN RHODOPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 LEPOC|Ensembl=ENSLOCG00000008892.1|UniProtKB=W5MR18 W5MR18 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001758.1|UniProtKB=W5M0W9 W5M0W9 PTHR15481:SF2 RIBONUCLEIC ACID BINDING PROTEIN S1 RNA-BINDING PROTEIN WITH SERINE-RICH DOMAIN 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002066.1|UniProtKB=W5M202 W5M202 PTHR45851:SF5 MYC PROTO-ONCOGENE PROTEIN L-MYC-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000017303.1|UniProtKB=W5NL99 W5NL99 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002412.1|UniProtKB=W5M3D2 W5M3D2 PTHR11453:SF105 ANION EXCHANGE PROTEIN SODIUM BICARBONATE COTRANSPORTER 3 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007025.1|UniProtKB=W5MJF1 W5MJF1 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE FAD SYNTHASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 transferase#PC00220;metabolite interconversion enzyme#PC00262 Flavin biosynthesis#P02741>FAD synthetase#P02936 LEPOC|Ensembl=ENSLOCG00000008384.1|UniProtKB=W5MP81 W5MP81 PTHR45792:SF2 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-BETA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;icosanoid metabolic process#GO:0006690;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 lipase#PC00143 LEPOC|Ensembl=ENSLOCG00000005490.1|UniProtKB=W5ME18 W5ME18 PTHR45636:SF19 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014655.1|UniProtKB=W5NBN8 W5NBN8 PTHR11455:SF15 CRYPTOCHROME CRYPTOCHROME-2 nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deoxyribodipyrimidine photo-lyase activity#GO:0003904;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501 LEPOC|Ensembl=ENSLOCG00000000166.1|UniProtKB=W5LVM8 W5LVM8 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018047.1|UniProtKB=W5NND9 W5NND9 PTHR24232:SF3 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011621.1|UniProtKB=W5N0X1 W5N0X1 PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000006767.1|UniProtKB=W5MIH2 W5MIH2 PTHR12431:SF19 SORTING NEXIN 17 AND 27 SORTING NEXIN-27 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018178.1|UniProtKB=W5NNS0 W5NNS0 PTHR12365:SF10 SPROUTY PROTEIN SPROUTY HOMOLOG 1 negative regulation of cellular metabolic process#GO:0031324;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of small GTPase mediated signal transduction#GO:0051058;negative regulation of protein kinase activity#GO:0006469;regulation of MAP kinase activity#GO:0043405;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511;FGF signaling pathway#P00021>Spry#P00626 LEPOC|Ensembl=ENSLOCG00000012282.1|UniProtKB=W5N3B2 W5N3B2 PTHR10160:SF22 NAD(P) TRANSHYDROGENASE NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007629.1|UniProtKB=W5MLJ5 W5MLJ5 PTHR46032:SF4 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosphingolipid biosynthetic process#GO:0006688;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012924.1|UniProtKB=W5N5K8 W5N5K8 PTHR14206:SF3 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016870.1|UniProtKB=W5NJP5 W5NJP5 PTHR11829:SF167 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003532.1|UniProtKB=W5M722 W5M722 PTHR11949:SF24 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000000643.1|UniProtKB=W5LX53 W5LX53 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015338.1|UniProtKB=W5NE24 W5NE24 PTHR45691:SF3 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 LEPOC|Ensembl=ENSLOCG00000007360.1|UniProtKB=W5MKK9 W5MKK9 PTHR16247:SF0 RIKEN CDNA 9430015G10 GENE RIKEN CDNA 9430015G10 GENE LEPOC|Ensembl=ENSLOCG00000006499.1|UniProtKB=W5MHJ9 W5MHJ9 PTHR11607:SF3 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003854.1|UniProtKB=W5M892 W5M892 PTHR11003:SF18 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 15 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007541.1|UniProtKB=W5ML94 W5ML94 PTHR11871:SF6 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B DELTA ISOFORM phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000004437.1|UniProtKB=W5MA94 W5MA94 PTHR14559:SF3 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002289.1|UniProtKB=W5M2S3 W5M2S3 PTHR46047:SF2 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;kinase binding#GO:0019900;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;regulation of receptor signaling pathway via STAT#GO:1904892;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of signaling#GO:0023057;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 cytoplasm#GO:0005737;endosome#GO:0005768;nucleus#GO:0005634;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Cadherin signaling pathway#P00012>Tyrosine phosphatases#P00472 LEPOC|Ensembl=ENSLOCG00000015314.1|UniProtKB=W5NDY6 W5NDY6 PTHR11242:SF1 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED PPIASE FKBP-TYPE DOMAIN-CONTAINING PROTEIN chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000899.1|UniProtKB=W5LXZ5 W5LXZ5 PTHR12086:SF9 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;alpha-tubulin binding#GO:0043014;binding#GO:0005488 cell division#GO:0051301;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cytokinesis#GO:0000910 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000015446.1|UniProtKB=W5NEF1 W5NEF1 PTHR48134:SF2 GLYCOPROTEIN 96-92-RELATED-RELATED OS04G0609100 PROTEIN LEPOC|Ensembl=ENSLOCG00000000308.1|UniProtKB=W5LW28 W5LW28 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002067.1|UniProtKB=W5M1Y8 W5M1Y8 PTHR32061:SF4 NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018085.1|UniProtKB=W5NNH7 W5NNH7 PTHR11214:SF291 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014929.1|UniProtKB=W5NCM4 W5NCM4 PTHR10264:SF130 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016458.1|UniProtKB=W5NI68 W5NI68 PTHR10841:SF6 SYNAPSIN SYNAPSIN III neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;signal release#GO:0023061;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;export from cell#GO:0140352;secretion by cell#GO:0032940 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003441.1|UniProtKB=W5M6S4 W5M6S4 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;TORC2 signaling#GO:0038203;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of neuronal synaptic plasticity#GO:0048168;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013482.1|UniProtKB=W5N7L9 W5N7L9 PTHR19305:SF4 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 23 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000012283.1|UniProtKB=W5N3A6 W5N3A6 PTHR11711:SF449 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000006789.1|UniProtKB=W5MIJ4 W5MIJ4 XAF1 PTHR16295:SF17 TRAF-TYPE ZINC FINGER PROTEIN-RELATED XIAP-ASSOCIATED FACTOR 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009222.1|UniProtKB=W5MS92 W5MS92 PTHR11551:SF4 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 5 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006967.1|UniProtKB=W5MJ69 W5MJ69 PTHR23277:SF106 NECTIN-RELATED NECTIN-1 ISOFORM X1-RELATED cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000018040.1|UniProtKB=W5NND2 W5NND2 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000005381.1|UniProtKB=W5MDM9 W5MDM9 PTHR13600:SF33 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004624.1|UniProtKB=W5MAY4 W5MAY4 PTHR24028:SF248 CADHERIN-87A PROTOCADHERIN-9 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000016436.1|UniProtKB=W5NI43 W5NI43 PTHR24042:SF0 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL2 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;glycosaminoglycan binding#GO:0005539;kinase binding#GO:0019900 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013707.1|UniProtKB=W5N8E2 W5N8E2 PTHR16196:SF0 CELL CYCLE CONTROL PROTEIN CWF25 PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011801.1|UniProtKB=W5N1K1 W5N1K1 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014902.1|UniProtKB=W5NCJ7 W5NCJ7 PTHR10269:SF4 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006784.1|UniProtKB=W5MII8 W5MII8 PTHR12771:SF18 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015182.1|UniProtKB=W5NDH5 W5NDH5 PTHR46051:SF8 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 2B inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010130.1|UniProtKB=W5MVJ1 W5MVJ1 PTHR11871:SF5 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B GAMMA ISOFORM phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000017168.1|UniProtKB=W5NKR0 W5NKR0 PTHR45636:SF44 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX 10-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015356.1|UniProtKB=W5NE45 W5NE45 PTHR33487:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002144.1|UniProtKB=W5M2B2 W5M2B2 PTHR11347:SF184 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;heterocycle catabolic process#GO:0046700;cyclic nucleotide metabolic process#GO:0009187;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;nucleotide catabolic process#GO:0009166;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;response to stimulus#GO:0050896;aromatic compound catabolic process#GO:0019439;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000018180.1|UniProtKB=W5NNS2 W5NNS2 PTHR15258:SF2 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 1 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 LEPOC|Ensembl=ENSLOCG00000015384.1|UniProtKB=W5NE75 W5NE75 PTHR21705:SF9 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 2B LEPOC|Ensembl=ENSLOCG00000000812.1|UniProtKB=W5LXP8 W5LXP8 PTHR23421:SF172 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 galactosidase#PC00104;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007264.1|UniProtKB=W5MK82 W5MK82 PTHR11276:SF21 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA NUCLEOTIDYLEXOTRANSFERASE DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000001647.1|UniProtKB=W5M0K8 W5M0K8 PTHR19143:SF243 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-2 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-2#P00246 LEPOC|Ensembl=ENSLOCG00000009895.1|UniProtKB=W5MUN1 W5MUN1 PTHR24179:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12A phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 supramolecular complex#GO:0099080;Z disc#GO:0030018;A band#GO:0031672;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;myofibril#GO:0030016;I band#GO:0031674 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000009497.1|UniProtKB=W5MT86 W5MT86 PTHR47084:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012547.1|UniProtKB=W5N496 W5N496 PTHR13803:SF5 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24C cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000002083.1|UniProtKB=W5M208 W5M208 OCSTAMP PTHR21041:SF3 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN OSTEOCLAST STIMULATORY TRANSMEMBRANE PROTEIN LEPOC|Ensembl=ENSLOCG00000004798.1|UniProtKB=W5MBK7 W5MBK7 PTHR24161:SF16 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC13 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000228.1|UniProtKB=W5LVU6 W5LVU6 PTHR12406:SF29 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;triglyceride catabolic process#GO:0019433;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000008391.1|UniProtKB=W5MP83 W5MP83 ASF1A PTHR12040:SF8 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009546.1|UniProtKB=W5MTF6 W5MTF6 PTHR12606:SF11 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 2 hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001531.1|UniProtKB=W5M071 W5M071 PTHR14043:SF4 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015929.1|UniProtKB=W5NG53 W5NG53 PTHR47972:SF65 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002632.1|UniProtKB=W5M3Z2 W5M3Z2 PTHR11232:SF35 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1 cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009162.1|UniProtKB=W5MS21 W5MS21 PTHR23140:SF3 RNA PROCESSING PROTEIN LD23810P SR-RELATED AND CTD-ASSOCIATED FACTOR 4 nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA binding#GO:0003723;RNA polymerase binding#GO:0070063;binding#GO:0005488;organic cyclic compound binding#GO:0097159;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;basal transcription machinery binding#GO:0001098 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011529.1|UniProtKB=W5N0K6 W5N0K6 PTHR21029:SF18 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 9-BINDING PROTEIN B regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000001878.1|UniProtKB=W5M1B5 W5M1B5 MED9 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mediator complex#GO:0016592;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007491.1|UniProtKB=W5ML35 W5ML35 PTHR24073:SF285 DRAB5-RELATED RAS-RELATED PROTEIN RAB-18 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011288.1|UniProtKB=W5MZR4 W5MZR4 PTHR10122:SF11 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B2 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009764.1|UniProtKB=W5MU70 W5MU70 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE HOMOLOG 5 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 LEPOC|Ensembl=ENSLOCG00000007117.1|UniProtKB=W5MJQ9 W5MJQ9 PTHR12459:SF15 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 LEPOC|Ensembl=ENSLOCG00000002937.1|UniProtKB=W5M500 W5M500 PTHR46752:SF1 G-PROTEIN COUPLED RECEPTOR 39 G-PROTEIN COUPLED RECEPTOR 39 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015825.1|UniProtKB=W5NFS0 W5NFS0 PTHR47979:SF46 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39A-LIKE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007574.1|UniProtKB=W5MLD3 W5MLD3 GPBP1 PTHR14339:SF11 VASCULIN VASCULIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016791.1|UniProtKB=W5NJF0 W5NJF0 PTHR24095:SF110 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 LEPOC|Ensembl=ENSLOCG00000003443.1|UniProtKB=W5M6S2 W5M6S2 PTHR48043:SF54 EG:EG0003.4 PROTEIN-RELATED 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006492.1|UniProtKB=W5MHI9 W5MHI9 PTHR11371:SF29 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 2 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000004884.1|UniProtKB=W5MBW5 W5MBW5 ZNF512B PTHR22979:SF3 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512B LEPOC|Ensembl=ENSLOCG00000003602.1|UniProtKB=W5M7A9 W5M7A9 PTHR10334:SF63 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 15 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015169.1|UniProtKB=W5NDH0 W5NDH0 PTHR24092:SF38 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IG ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008672.1|UniProtKB=W5MQ96 W5MQ96 PTHR24025:SF22 DESMOGLEIN FAMILY MEMBER CADHERIN DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000004128.1|UniProtKB=W5M978 W5M978 PTHR24073:SF555 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000018260.1|UniProtKB=W5NP02 W5NP02 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004492.1|UniProtKB=W5MAG2 W5MAG2 PTHR20855:SF107 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR 2 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013658.1|UniProtKB=W5N880 W5N880 PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary miRNA processing#GO:0031053;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002586.1|UniProtKB=W5M3V3 W5M3V3 PTHR46513:SF16 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5 system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 LEPOC|Ensembl=ENSLOCG00000012233.1|UniProtKB=W5N337 W5N337 PTHR11988:SF28 THYROTROPH EMBRYONIC FACTOR RELATED HEPATIC LEUKEMIA FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000005703.1|UniProtKB=W5MES4 W5MES4 BHLHA9 PTHR23349:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008686.1|UniProtKB=W5MQA2 W5MQA2 PTHR35978:SF1 IQ DOMAIN-CONTAINING PROTEIN M IQ DOMAIN-CONTAINING PROTEIN M LEPOC|Ensembl=ENSLOCG00000003271.1|UniProtKB=W5M655 W5M655 PTHR18870:SF8 PROTEIN TAG-278-RELATED PROTEIN FAM184B LEPOC|Ensembl=ENSLOCG00000017636.1|UniProtKB=W5NM82 W5NM82 PTHR10489:SF937 CELL ADHESION MOLECULE RELAXIN-3 RECEPTOR 1 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017159.1|UniProtKB=W5NKP9 W5NKP9 PTHR33331:SF13 COILED-COIL DOMAIN-CONTAINING PROTEIN 162 COILED-COIL DOMAIN CONTAINING 162 LEPOC|Ensembl=ENSLOCG00000005469.1|UniProtKB=W5MDY5 W5MDY5 PTHR10442:SF0 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002603.1|UniProtKB=W5M3U9 W5M3U9 PTHR25480:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 C-MAF-INDUCING PROTEIN LEPOC|Ensembl=ENSLOCG00000016330.1|UniProtKB=W5NHP9 W5NHP9 PTHR11805:SF1 CYSTEINE-RICH PDZ-BINDING PROTEIN CYSTEINE-RICH PDZ-BINDING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 LEPOC|Ensembl=ENSLOCG00000009959.1|UniProtKB=W5MUX0 W5MUX0 PTHR12146:SF0 40S RIBOSOMAL PROTEIN S10 RIBOSOMAL PROTEIN S10 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012163.1|UniProtKB=W5N2W8 W5N2W8 PTHR45703:SF4 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 17 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006536.1|UniProtKB=W5MHN8 W5MHN8 PTHR12306:SF16 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR SUBUNIT ALPHA biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 LEPOC|Ensembl=ENSLOCG00000014347.1|UniProtKB=W5NAK9 W5NAK9 PTHR47977:SF81 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014723.1|UniProtKB=W5NBW8 W5NBW8 PTHR10083:SF217 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED BOOPHILIN-H2 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012927.1|UniProtKB=W5N5L7 W5N5L7 PTHR12544:SF26 GLUTAMINASE GLUTAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 dicarboxylic acid metabolic process#GO:0043648;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017150.1|UniProtKB=W5NKN5 W5NKN5 PTHR24064:SF186 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 16 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic cation transport#GO:0015695;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000424.1|UniProtKB=W5LWF5 W5LWF5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005931.1|UniProtKB=W5MFJ9 W5MFJ9 TCTN2 PTHR14611:SF6 TECTONIC FAMILY MEMBER TECTONIC-2 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 LEPOC|Ensembl=ENSLOCG00000006108.1|UniProtKB=W5MG72 W5MG72 KLHL6 PTHR24412:SF428 KELCH PROTEIN KELCH-LIKE PROTEIN 6 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012186.1|UniProtKB=W5N2X7 W5N2X7 RNF138 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000009203.1|UniProtKB=W5MS66 W5MS66 PTHR15944:SF2 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE-LIKE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000017292.1|UniProtKB=W5NL88 W5NL88 PTHR45643:SF16 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000011875.1|UniProtKB=W5N1U8 W5N1U8 PTHR45962:SF1 N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1 N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006569.1|UniProtKB=W5MHS4 W5MHS4 PTHR46756:SF9 TRANSGELIN GROWTH ARREST-SPECIFIC PROTEIN 2 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000005026.1|UniProtKB=W5MCE1 W5MCE1 PTHR12366:SF33 ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE ASPARTYL_ASPARAGINYL BETA-HYDROXYLASE macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein hydroxylation#GO:0018126;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014255.1|UniProtKB=W5NA91 W5NA91 PTHR46040:SF1 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 20A-RELATED regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009386.1|UniProtKB=W5MSW3 W5MSW3 PTHR45994:SF2 FI21225P1 PROTEIN UNC-45 HOMOLOG B protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;Hsp90 protein binding#GO:0051879 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009108.1|UniProtKB=W5MRU5 W5MRU5 PTHR22776:SF42 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEIN MAL2 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000827.1|UniProtKB=W5LXR3 W5LXR3 PTHR12002:SF184 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000014485.1|UniProtKB=W5NB16 W5NB16 EOLA1 PTHR31666:SF0 PROTEIN CXORF40A-RELATED PROTEIN EOLA1-RELATED LEPOC|Ensembl=ENSLOCG00000017411.1|UniProtKB=W5NLK7 W5NLK7 PTHR23137:SF36 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2C LEPOC|Ensembl=ENSLOCG00000011768.1|UniProtKB=W5N1G5 W5N1G5 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000007563.1|UniProtKB=W5MLB9 W5MLB9 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 regulation of anatomical structure size#GO:0090066;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017463.1|UniProtKB=W5NLQ9 W5NLQ9 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000887.1|UniProtKB=W5LXY9 W5LXY9 PTHR23065:SF6 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 1 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012808.1|UniProtKB=W5N552 W5N552 PLEKHG3 PTHR45924:SF4 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000008757.1|UniProtKB=W5MQL3 W5MQL3 PTHR24293:SF0 CYTOCHROME P450 FAMILY 46 SUBFAMILY A CYP46A1 PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;heme binding#GO:0020037 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid catabolic process#GO:0006706;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;secondary alcohol metabolic process#GO:1902652;organic substance catabolic process#GO:1901575;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001724.1|UniProtKB=W5M0T0 W5M0T0 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007600.1|UniProtKB=W5MLF8 W5MLF8 PTHR46176:SF3 LD21662P PROTEIN FAM76B membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000722.1|UniProtKB=W5LXG2 W5LXG2 PTHR16484:SF10 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of cell polarity#GO:0030010;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;centrosome localization#GO:0051642;establishment of localization in cell#GO:0051649;establishment or maintenance of apical/basal cell polarity#GO:0035088;cytoskeleton organization#GO:0007010;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324 LEPOC|Ensembl=ENSLOCG00000008626.1|UniProtKB=W5MQ56 W5MQ56 PTHR23169:SF20 ENVOPLAKIN PLECTIN structural constituent of muscle#GO:0008307;cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;wound healing#GO:0042060;cellular component organization#GO:0016043;cellular process#GO:0009987;response to stimulus#GO:0050896;cell-substrate junction assembly#GO:0007044;cellular component organization or biogenesis#GO:0071840;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;cell junction assembly#GO:0034329;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;perinuclear region of cytoplasm#GO:0048471;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000013632.1|UniProtKB=W5N846 W5N846 PTHR23036:SF101 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 LEPOC|Ensembl=ENSLOCG00000012490.1|UniProtKB=W5N421 W5N421 PTHR22014:SF2 RNA-BINDING PROTEIN 33 RNA-BINDING PROTEIN 33 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 LEPOC|Ensembl=ENSLOCG00000013434.1|UniProtKB=W5N7F3 W5N7F3 PTHR13211:SF0 TELOMERASE CAJAL BODY PROTEIN 1 TELOMERASE CAJAL BODY PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000018364.1|UniProtKB=W5NPA6 W5NPA6 PTHR13832:SF779 PROTEIN PHOSPHATASE 2C SI:CH211-15P9.2 PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012075.1|UniProtKB=W5N2J7 W5N2J7 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017453.1|UniProtKB=W5NLP9 W5NLP9 PTHR26451:SF847 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006808.1|UniProtKB=W5MIL4 W5MIL4 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010352.1|UniProtKB=W5MWD2 W5MWD2 PTHR45760:SF5 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A40-RELATED localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002840.1|UniProtKB=W5M4N1 W5M4N1 PTHR11730:SF48 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER AMTB-LIKE DOMAIN-CONTAINING PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002114.1|UniProtKB=W5M247 W5M247 PTHR11576:SF15 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3-LIKE enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000007353.1|UniProtKB=W5MKK4 W5MKK4 PTHR24347:SF388 SERINE/THREONINE-PROTEIN KINASE DEATH-ASSOCIATED PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014365.1|UniProtKB=W5NAN1 W5NAN1 PTHR45832:SF9 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000018148.1|UniProtKB=W5NNP0 W5NNP0 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000004464.1|UniProtKB=W5MAC8 W5MAC8 PTHR16027:SF3 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;stem cell development#GO:0048864;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;cell development#GO:0048468;cell differentiation#GO:0030154;neural crest cell differentiation#GO:0014033;mesenchyme development#GO:0060485;anatomical structure development#GO:0048856;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;cell migration#GO:0016477 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016011.1|UniProtKB=W5NGG4 W5NGG4 PTHR12092:SF1 PLECKSTRIN PLECKSTRIN cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017674.1|UniProtKB=W5NMC0 W5NMC0 PTHR45822:SF8 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to fatty acid#GO:0070542;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to fatty acid#GO:0071398;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017556.1|UniProtKB=W5NM02 W5NM02 PTHR24232:SF112 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006405.1|UniProtKB=W5MH79 W5MH79 PTHR11760:SF32 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012177.1|UniProtKB=W5N2W3 W5N2W3 FAM72B PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009682.1|UniProtKB=W5MTZ7 W5MTZ7 PTHR45628:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1E calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655;signaling#GO:0023052;import into cell#GO:0098657 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 LEPOC|Ensembl=ENSLOCG00000001067.1|UniProtKB=W5LYL9 W5LYL9 PTHR23189:SF51 RNA RECOGNITION MOTIF-CONTAINING SPLICING FACTOR, PROLINE- AND GLUTAMINE-RICH regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018149.1|UniProtKB=W5NNP1 W5NNP1 TSSK1B PTHR43895:SF32 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE CHK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000009963.1|UniProtKB=W5MUX3 W5MUX3 PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010798.1|UniProtKB=W5MXX6 W5MXX6 PTHR10218:SF73 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Enkephalin release#P05913>G-Protein (i)#P05974;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Opioid proenkephalin pathway#P05915>G-protein#P05994;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid prodynorphin pathway#P05916>G-protein#P06002;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 LEPOC|Ensembl=ENSLOCG00000004687.1|UniProtKB=W5MB81 W5MB81 PTHR10509:SF93 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000003983.1|UniProtKB=W5M8P2 W5M8P2 PTHR14715:SF2 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124B membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002250.1|UniProtKB=W5M2L3 W5M2L3 PTHR23328:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF169 nucleosome binding#GO:0031491;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015365.1|UniProtKB=W5NE51 W5NE51 PTHR12114:SF7 PARVIN BETA-PARVIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;substrate adhesion-dependent cell spreading#GO:0034446;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell leading edge#GO:0031252;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;cell projection#GO:0042995 actin and actin related protein#PC00039;cytoskeletal protein#PC00085 Integrin signalling pathway#P00034>Parvin#P00945 LEPOC|Ensembl=ENSLOCG00000013761.1|UniProtKB=W5N8M1 W5N8M1 PTHR11533:SF174 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016718.1|UniProtKB=W5NJ45 W5NJ45 PTHR24113:SF15 RAN GTPASE-ACTIVATING PROTEIN 1 NACHT DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 cellular localization#GO:0051641;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;transport#GO:0006810;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;localization#GO:0051179;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of hydrolase activity#GO:0051336;intracellular transport#GO:0046907;nuclear transport#GO:0051169 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001548.1|UniProtKB=W5M064 W5M064 PTHR15359:SF7 IG-LIKE DOMAIN-CONTAINING PROTEIN CALMODULIN REGULATOR PROTEIN PCP4 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;calmodulin binding#GO:0005516;ion binding#GO:0043167 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 LEPOC|Ensembl=ENSLOCG00000017289.1|UniProtKB=W5NL78 W5NL78 PTHR24249:SF220 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 4 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001949.1|UniProtKB=W5M1L2 W5M1L2 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008809.1|UniProtKB=W5MQR0 W5MQR0 PTHR45532:SF1 WD REPEAT-CONTAINING PROTEIN 97 WD REPEAT-CONTAINING PROTEIN 97 LEPOC|Ensembl=ENSLOCG00000003909.1|UniProtKB=W5M8F6 W5M8F6 PTHR11261:SF3 INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN RETINOL-BINDING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000017695.1|UniProtKB=W5NME1 W5NME1 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016233.1|UniProtKB=W5NHA6 W5NHA6 PTHR10190:SF17 EYES ABSENT EYES ABSENT HOMOLOG 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of DNA repair#GO:0045739;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of DNA repair#GO:0006282;regulation of biological process#GO:0050789;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of response to stress#GO:0080134;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000010259.1|UniProtKB=W5MW02 W5MW02 PTHR11746:SF147 O-METHYLTRANSFERASE HYDROXYINDOLE O-METHYLTRANSFERASE ISOFORM X1 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;hormone biosynthetic process#GO:0042446;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;hormone metabolic process#GO:0042445;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012608.1|UniProtKB=W5N4G2 W5N4G2 PTHR46152:SF2 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000002470.1|UniProtKB=W5M3G4 W5M3G4 PTHR11640:SF49 NEPHRIN KIN OF IRRE-LIKE PROTEIN 3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008958.1|UniProtKB=W5MRA0 W5MRA0 PTHR13943:SF37 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000013266.1|UniProtKB=W5N6T5 W5N6T5 PTHR23320:SF143 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A-LIKE ISOFORM X1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011739.1|UniProtKB=W5N1C5 W5N1C5 PTHR31397:SF1 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000000783.1|UniProtKB=W5LXL1 W5LXL1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003528.1|UniProtKB=W5M713 W5M713 PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016701.1|UniProtKB=W5NJ26 W5NJ26 PTHR14030:SF26 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;catalytic activity#GO:0003824;protein kinase activity#GO:0004672 meiotic sister chromatid cohesion#GO:0051177;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;sister chromatid cohesion#GO:0007062;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018365.1|UniProtKB=W5NPA7 W5NPA7 PTHR10270:SF295 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 sensory organ morphogenesis#GO:0090596;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;eye morphogenesis#GO:0048592;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;central nervous system development#GO:0007417;negative regulation of DNA-templated transcription#GO:0045892;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;negative regulation of metabolic process#GO:0009892;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;camera-type eye morphogenesis#GO:0048593;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000003024.1|UniProtKB=W5M5B8 W5M5B8 PTHR12308:SF51 ANOCTAMIN ANOCTAMIN-8 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002451.1|UniProtKB=W5M3C1 W5M3C1 PTHR12487:SF3 TEASHIRT-RELATED TEASHIRT HOMOLOG 2 nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013756.1|UniProtKB=W5N8K2 W5N8K2 PTHR32222:SF1 CENTROMERE PROTEIN U CENTROMERE PROTEIN U membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013111.1|UniProtKB=W5N692 W5N692 PTHR10533:SF14 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PEPTIDE YY-RELATED neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;behavior#GO:0007610;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;feeding behavior#GO:0007631;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014390.1|UniProtKB=W5NAR4 W5NAR4 IMPDH PTHR11911:SF121 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 LEPOC|Ensembl=ENSLOCG00000013976.1|UniProtKB=W5N9B7 W5N9B7 SGCZ PTHR12939:SF5 SARCOGLYCAN ZETA-SARCOGLYCAN blood circulation#GO:0008015;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;developmental process#GO:0032502;circulatory system process#GO:0003013;tissue development#GO:0009888;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000007934.1|UniProtKB=W5MMP0 W5MMP0 PTHR45818:SF1 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;cell motility#GO:0048870;cell migration#GO:0016477;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 LEPOC|Ensembl=ENSLOCG00000005116.1|UniProtKB=W5MCQ9 W5MCQ9 PTHR24271:SF54 KALLIKREIN-RELATED COMPLEMENT FACTOR D serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011709.1|UniProtKB=W5N183 W5N183 C7orf31 PTHR31393:SF2 C5ORF31 CHROMOSOME 7 OPEN READING FRAME 31 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000007562.1|UniProtKB=W5MLB8 W5MLB8 PTHR10865:SF22 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012518.1|UniProtKB=W5N457 W5N457 PTHR45956:SF4 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 1 cellular localization#GO:0051641;regulation of endocytosis#GO:0030100;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017596.1|UniProtKB=W5NM42 W5NM42 PTHR22794:SF2 THAP DOMAIN PROTEIN 11 THAP DOMAIN-CONTAINING PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000010711.1|UniProtKB=W5MXM2 W5MXM2 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;homologous chromosome segregation#GO:0045143;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;reciprocal homologous recombination#GO:0140527;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;reciprocal meiotic recombination#GO:0007131;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic DNA integrity checkpoint signaling#GO:0044774;homologous recombination#GO:0035825;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007446.1|UniProtKB=W5MKY1 W5MKY1 PTHR10807:SF66 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;regulation of catabolic process#GO:0009894;phosphatidylinositol dephosphorylation#GO:0046856;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;regulation of cellular catabolic process#GO:0031329;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000012853.1|UniProtKB=W5N5B6 W5N5B6 PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000016270.1|UniProtKB=W5NHG1 W5NHG1 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 lyase activity#GO:0016829;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;peptide catabolic process#GO:0043171;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009275.1|UniProtKB=W5MSG2 W5MSG2 PTHR24221:SF503 ATP-BINDING CASSETTE SUB-FAMILY B MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014406.1|UniProtKB=W5NAS2 W5NAS2 PTHR11787:SF3 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR ALPHA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003055.1|UniProtKB=W5M5D9 W5M5D9 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014701.1|UniProtKB=W5NBT7 W5NBT7 PTHR12697:SF20 PBS LYASE HEAT-LIKE PROTEIN HEAT REPEAT-CONTAINING PROTEIN 4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000004167.1|UniProtKB=W5M9E8 W5M9E8 PTHR46097:SF4 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT2 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 head development#GO:0060322;regulation of cell communication#GO:0010646;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;brain development#GO:0007420;vesicle-mediated transport#GO:0016192;regulation of G protein-coupled receptor signaling pathway#GO:0008277;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;system development#GO:0048731;synaptic vesicle recycling#GO:0036465;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;central nervous system development#GO:0007417;vesicle-mediated transport in synapse#GO:0099003 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016717.1|UniProtKB=W5NJ46 W5NJ46 PTHR23240:SF8 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED PROTEIN ARTEMIS hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016296.1|UniProtKB=W5NHK0 W5NHK0 PTHR23209:SF4 A-KINASE ANCHOR PROTEIN 12 A-KINASE ANCHOR PROTEIN 12 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014926.1|UniProtKB=W5NCM3 W5NCM3 PTHR13136:SF16 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000014588.1|UniProtKB=W5NBE4 W5NBE4 PTHR24366:SF166 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000009585.1|UniProtKB=W5MTK0 W5MTK0 PTHR10634:SF26 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000006146.1|UniProtKB=W5MGB6 W5MGB6 PTHR22589:SF16 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017301.1|UniProtKB=W5NL97 W5NL97 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017891.1|UniProtKB=W5NMY5 W5NMY5 PTHR24235:SF19 NEUROPEPTIDE Y RECEPTOR PROLACTIN RELEASING PEPTIDE RECEPTOR-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003420.1|UniProtKB=W5M6P2 W5M6P2 PTHR44154:SF1 QUINONE OXIDOREDUCTASE QUINONE OXIDOREDUCTASE oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000013566.1|UniProtKB=W5N7W3 W5N7W3 PTHR24215:SF31 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE RICH PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007856.1|UniProtKB=W5MMC7 W5MMC7 PTHR23235:SF29 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003350.1|UniProtKB=W5M6F1 W5M6F1 PTHR10582:SF5 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000355.1|UniProtKB=W5LW81 W5LW81 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007734.1|UniProtKB=W5MLY1 W5MLY1 SDS PTHR48078:SF8 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE DEHYDRATASE_L-THREONINE DEAMINASE lyase activity#GO:0016829;catalytic activity#GO:0003824 branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000012628.1|UniProtKB=W5N4J2 W5N4J2 PTHR13369:SF0 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011349.1|UniProtKB=W5MZZ1 W5MZZ1 PTHR48041:SF82 ABC TRANSPORTER G FAMILY MEMBER 28 ATP BINDING CASSETTE SUBFAMILY G MEMBER 2 (JUNIOR BLOOD GROUP) transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006400.1|UniProtKB=W5MH71 W5MH71 PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000009902.1|UniProtKB=W5MUP6 W5MUP6 PTHR12548:SF4 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014729.1|UniProtKB=W5NBX7 W5NBX7 PTHR10933:SF9 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN-BINDING PROTEIN 1 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of phosphate metabolic process#GO:0019220;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of dephosphorylation#GO:0035303;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005633.1|UniProtKB=W5MEI9 W5MEI9 PTHR31671:SF4 DIABETES AND OBESITY REGULATED, ISOFORM G SI:CH211-260E23.9 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of biosynthetic process#GO:0009891;vacuole organization#GO:0007033;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;positive regulation of RNA metabolic process#GO:0051254;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015155.1|UniProtKB=W5NDE1 W5NDE1 PTHR19818:SF25 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014382.1|UniProtKB=W5NAP7 W5NAP7 PTHR20855:SF35 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016990.1|UniProtKB=W5NK48 W5NK48 USP15 PTHR21646:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001426.1|UniProtKB=W5LZR9 W5LZR9 PTHR24254:SF9 PROTHROMBIN INACTIVE SERINE PROTEASE PAMR1 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005856.1|UniProtKB=W5MFB5 W5MFB5 PTHR15708:SF8 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006462.1|UniProtKB=W5MHF0 W5MHF0 PTHR10972:SF53 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013475.1|UniProtKB=W5N7K5 W5N7K5 PTHR23350:SF4 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 2 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015335.1|UniProtKB=W5NE09 W5NE09 PTHR45931:SF15 SI:CH211-59O9.10 SI:CH211-59O9.10 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;proteolysis#GO:0006508;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002636.1|UniProtKB=W5M3Z1 W5M3Z1 PTHR19300:SF32 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 2 galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006320.1|UniProtKB=W5MGX0 W5MGX0 PTHR12845:SF10 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN-1-LIKE positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015196.1|UniProtKB=W5NDJ3 W5NDJ3 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 basal plasma membrane#GO:0009925;synapse#GO:0045202;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000016064.1|UniProtKB=W5NGN2 W5NGN2 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010369.1|UniProtKB=W5MWE6 W5MWE6 PTHR24247:SF212 5-HYDROXYTRYPTAMINE RECEPTOR PARIETOPSIN signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009920.1|UniProtKB=W5MUR7 W5MUR7 PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000003362.1|UniProtKB=W5M6H2 W5M6H2 PTHR10196:SF67 SUGAR KINASE SEDOHEPTULOKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 LEPOC|Ensembl=ENSLOCG00000014024.1|UniProtKB=W5N9H8 W5N9H8 PTHR23200:SF48 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003747.1|UniProtKB=W5M7V7 W5M7V7 PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010321.1|UniProtKB=W5MWB8 W5MWB8 PTHR24044:SF421 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 LEPOC|Ensembl=ENSLOCG00000016832.1|UniProtKB=W5NJL7 W5NJL7 PTHR13817:SF22 TITIN MYOMESIN-2 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006300.1|UniProtKB=W5MGV2 W5MGV2 PTHR10865:SF27 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014627.1|UniProtKB=W5NBJ3 W5NBJ3 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;regulation of neuron differentiation#GO:0045664;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011061.1|UniProtKB=W5MYX7 W5MYX7 UTP18 PTHR18359:SF0 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000017199.1|UniProtKB=W5NKV0 W5NKV0 PTHR14431:SF1 HCLS1-BINDING PROTEIN 3 HCLS1-BINDING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000007614.1|UniProtKB=W5MLJ3 W5MLJ3 PTHR12458:SF8 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 LEPOC|Ensembl=ENSLOCG00000002389.1|UniProtKB=W5M347 W5M347 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003110.1|UniProtKB=W5M5L1 W5M5L1 EIF3E PTHR10317:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006510.1|UniProtKB=W5MHK4 W5MHK4 INTS15 PTHR14540:SF2 INTEGRATOR COMPLEX SUBUNIT 15 INTEGRATOR COMPLEX SUBUNIT 15 LEPOC|Ensembl=ENSLOCG00000007559.1|UniProtKB=W5MLB4 W5MLB4 PTHR24056:SF111 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010319.1|UniProtKB=W5MW94 W5MW94 PTHR15117:SF2 ATAXIN 7 RELATED ATAXIN-7 LEPOC|Ensembl=ENSLOCG00000012873.1|UniProtKB=W5N5D8 W5N5D8 PTHR16055:SF2 INTEGRATOR COMPLEX SUBUNIT 10 INTEGRATOR COMPLEX SUBUNIT 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 LEPOC|Ensembl=ENSLOCG00000001398.1|UniProtKB=W5LZN0 W5LZN0 PTHR21311:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014779.1|UniProtKB=W5NC41 W5NC41 PTHR45805:SF3 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003888.1|UniProtKB=W5M8D1 W5M8D1 PTHR25466:SF14 T-LYMPHOCYTE ACTIVATION ANTIGEN BUTYROPHILIN SUBFAMILY 2 MEMBER A2-LIKE-RELATED response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015999.1|UniProtKB=W5NGE5 W5NGE5 PTHR46094:SF1 INTEGRATOR COMPLEX SUBUNIT 9 INTEGRATOR COMPLEX SUBUNIT 9 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 LEPOC|Ensembl=ENSLOCG00000001659.1|UniProtKB=W5M0K9 W5M0K9 PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012950.1|UniProtKB=W5N5N8 W5N5N8 PTHR22419:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013348.1|UniProtKB=W5N740 W5N740 CCDC66 PTHR22736:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000000039.1|UniProtKB=W5LV88 W5LV88 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016095.1|UniProtKB=W5NGS6 W5NGS6 PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;ribosome biogenesis#GO:0042254;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004886.1|UniProtKB=W5MBW6 W5MBW6 PTHR24331:SF6 DBX HOMEOBOX PROTEIN DBX1 cellular developmental process#GO:0048869;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000008446.1|UniProtKB=W5MPH9 W5MPH9 PTHR13407:SF2 RNF121 PROTEIN RING FINGER PROTEIN 175 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013695.1|UniProtKB=W5N8C6 W5N8C6 PTHR23249:SF16 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014123.1|UniProtKB=W5N9U2 W5N9U2 PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000130.1|UniProtKB=W5LVI7 W5LVI7 PTHR46013:SF1 VASCULAR CELL ADHESION MOLECULE 1 IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005310.1|UniProtKB=W5MDE9 W5MDE9 PTHR12811:SF0 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;cellular localization#GO:0051641;vacuole organization#GO:0007033;establishment of localization#GO:0051234;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007723.1|UniProtKB=W5MLW4 W5MLW4 PTHR44733:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 cellular anatomical entity#GO:0110165;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015900.1|UniProtKB=W5NG27 W5NG27 PTHR10574:SF233 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 integrin binding#GO:0005178;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000014757.1|UniProtKB=W5NC31 W5NC31 PTHR16166:SF125 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13C establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein localization to Golgi apparatus#GO:0034067;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;maintenance of location#GO:0051235;organelle organization#GO:0006996;maintenance of location in cell#GO:0051651;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;intracellular transport#GO:0046907 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008782.1|UniProtKB=W5MQN3 W5MQN3 PTHR15459:SF3 POLYAMINE-MODULATED FACTOR 1 POLYAMINE-MODULATED FACTOR 1 cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;outer kinetochore#GO:0000940;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome#GO:0000793;condensed chromosome, centromeric region#GO:0000779;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002088.1|UniProtKB=W5M219 W5M219 PTHR14477:SF1 CUB DOMAIN-CONTAINING PROTEIN 1 CUB DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017774.1|UniProtKB=W5NML9 W5NML9 PTHR24237:SF7 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 183 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005535.1|UniProtKB=W5ME77 W5ME77 PTHR47077:SF1 ION_TRANS DOMAIN-CONTAINING PROTEIN CATION CHANNEL SPERM-ASSOCIATED PROTEIN 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;establishment of localization#GO:0051234;spermatogenesis#GO:0007283;monoatomic cation transport#GO:0006812;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;metal ion transport#GO:0030001;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;sodium ion transport#GO:0006814;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;secretory granule#GO:0030141;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;vesicle#GO:0031982;intracellular organelle#GO:0043229;voltage-gated calcium channel complex#GO:0005891;motile cilium#GO:0031514;CatSper complex#GO:0036128;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;cilium#GO:0005929;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;sperm principal piece#GO:0097228;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001681.1|UniProtKB=W5M0M3 W5M0M3 PTHR11304:SF4 EPHRIN EPHRIN-A2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;osteoclast differentiation#GO:0030316;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001556.1|UniProtKB=W5M073 W5M073 PTHR44991:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 5 IMMUNOGLOBULIN SUPERFAMILY MEMBER 5 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006443.1|UniProtKB=W5MHE7 W5MHE7 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPONENT 10 LEPOC|Ensembl=ENSLOCG00000006155.1|UniProtKB=W5MGC7 W5MGC7 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003661.1|UniProtKB=W5M7I6 W5M7I6 PTHR46311:SF1 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 7 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011747.1|UniProtKB=W5N1E4 W5N1E4 PTHR22812:SF134 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011664.1|UniProtKB=W5N121 W5N121 C18orf32 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 LEPOC|Ensembl=ENSLOCG00000006173.1|UniProtKB=W5MGF2 W5MGF2 PTHR20275:SF30 NAD KINASE NAD(+) KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000008329.1|UniProtKB=W5MP06 W5MP06 PTHR21353:SF7 FAMILY NOT NAMED CARDIOTROPHIN-LIKE CYTOKINE FACTOR 1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012039.1|UniProtKB=W5N2E8 W5N2E8 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015031.1|UniProtKB=W5NCZ2 W5NCZ2 PTHR24388:SF99 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF52.1-LIKE ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007970.1|UniProtKB=W5MMT0 W5MMT0 PTHR11616:SF318 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013670.1|UniProtKB=W5N8A2 W5N8A2 PTHR18871:SF2 CENTROSOMAL PROTEIN OF 112 KDA CENTROSOMAL PROTEIN OF 112 KDA LEPOC|Ensembl=ENSLOCG00000010960.1|UniProtKB=W5MYI9 W5MYI9 PTHR24192:SF3 ANKYRIN REPEAT DOMAIN 40 ANKYRIN REPEAT DOMAIN 40 LEPOC|Ensembl=ENSLOCG00000012946.1|UniProtKB=W5N5N0 W5N5N0 PTHR10489:SF922 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR FAMILY-LIKE-RELATED signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015554.1|UniProtKB=W5NET9 W5NET9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003567.1|UniProtKB=W5M772 W5M772 PTHR14167:SF6 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017036.1|UniProtKB=W5NK97 W5NK97 PTHR12472:SF0 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003434.1|UniProtKB=W5M6Q9 W5M6Q9 PTHR23192:SF31 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006332.1|UniProtKB=W5MGY4 W5MGY4 PTHR22923:SF89 CEREBELLIN-RELATED CEREBELLIN 18 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002119.1|UniProtKB=W5M263 W5M263 PTHR24031:SF761 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX49-RELATED RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000003951.1|UniProtKB=W5M8L3 W5M8L3 PTHR46453:SF5 PROTEIN KINASE C-BINDING PROTEIN 1 PROTEIN KINASE C-BINDING PROTEIN 1 ISOFORM X1 transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015473.1|UniProtKB=W5NEI6 W5NEI6 PTHR10338:SF155 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H6 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005567.1|UniProtKB=W5MEC0 W5MEC0 PTHR24028:SF263 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000015770.1|UniProtKB=W5NFL5 W5NFL5 PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004921.1|UniProtKB=W5MC07 W5MC07 PTHR10546:SF4 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL SUBUNIT BETA-3 protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;blood circulation#GO:0008015;regulation of sodium ion transport#GO:0002028;actin filament-based movement#GO:0030048;regulation of metal ion transport#GO:0010959;system process#GO:0003008;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007465.1|UniProtKB=W5ML00 W5ML00 PTHR31169:SF2 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 7 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003329.1|UniProtKB=W5M6C8 W5M6C8 PTHR21184:SF4 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151A extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000009862.1|UniProtKB=W5MUJ6 W5MUJ6 PTHR21292:SF7 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE 2 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015309.1|UniProtKB=W5NDX7 W5NDX7 PTHR13163:SF0 SPINAL CORD EXPRESSION PROTEIN 4 NOVEL ACETYLCHOLINE RECEPTOR CHAPERONE cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;chaperone-mediated protein complex assembly#GO:0051131;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007415.1|UniProtKB=W5MKT4 W5MKT4 PTHR47139:SF3 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 SI:CH73-361P23.3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001896.1|UniProtKB=W5M1E1 W5M1E1 PTHR45884:SF1 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000002804.1|UniProtKB=W5M4K0 W5M4K0 PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009879.1|UniProtKB=W5MUL6 W5MUL6 PTHR12281:SF16 RP42 RELATED DCN1-LIKE PROTEIN 2 cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015224.1|UniProtKB=W5NDN1 W5NDN1 PTHR23042:SF48 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000013136.1|UniProtKB=W5N6B9 W5N6B9 PTHR10252:SF5 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DR1-ASSOCIATED COREPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;core promoter sequence-specific DNA binding#GO:0001046;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006678.1|UniProtKB=W5MI51 W5MI51 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 LEPOC|Ensembl=ENSLOCG00000003883.1|UniProtKB=W5M8C7 W5M8C7 PTHR43340:SF7 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;transferase activity#GO:0016740;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;IMP metabolic process#GO:0046040;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015700.1|UniProtKB=W5NFB9 W5NFB9 PTHR12394:SF11 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-2 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000007702.1|UniProtKB=W5MLW0 W5MLW0 PTHR46221:SF9 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER NON-SPECIFIC PROTEIN-TYROSINE KINASE Angiogenesis#P00005>FAK#P00209;VEGF signaling pathway#P00056>FAK#P01420;Integrin signalling pathway#P00034>FAK#P00932 LEPOC|Ensembl=ENSLOCG00000017354.1|UniProtKB=W5NLF0 W5NLF0 PTHR46617:SF1 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015755.1|UniProtKB=W5NFI7 W5NFI7 PTHR12673:SF12 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006661.1|UniProtKB=W5MI35 W5MI35 SGO1 PTHR21577:SF3 SHUGOSHIN SHUGOSHIN 1-RELATED centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000003298.1|UniProtKB=W5M693 W5M693 TRABD2A PTHR31120:SF7 METALLOPROTEASE TIKI METALLOPROTEASE TIKI1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008735.1|UniProtKB=W5MQH3 W5MQH3 PTHR11660:SF47 SOLUTE CARRIER FAMILY 40 MEMBER SOLUTE CARRIER FAMILY 40 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;peptide hormone binding#GO:0017046;transmembrane transporter activity#GO:0022857;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;amide binding#GO:0033218;peptide binding#GO:0042277;hormone binding#GO:0042562;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;iron ion transmembrane transport#GO:0034755;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011935.1|UniProtKB=W5N223 W5N223 PTHR12223:SF28 VESICULAR MANNOSE-BINDING LECTIN LECTIN, MANNOSE BINDING 1 LIKE carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488;monosaccharide binding#GO:0048029 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011114.1|UniProtKB=W5MZ48 W5MZ48 PTHR46025:SF1 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-xylosyltransferase activity#GO:0035252;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005032.1|UniProtKB=W5MCF4 W5MCF4 PTHR43807:SF6 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 3 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014750.1|UniProtKB=W5NC20 W5NC20 PTHR46055:SF4 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN CLOCK PROTEIN PASD1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005102.1|UniProtKB=W5MCN4 W5MCN4 PTHR11848:SF159 TGF-BETA FAMILY NODAL HOMOLOG molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000017043.1|UniProtKB=W5NKA3 W5NKA3 PTHR24033:SF234 EGF-LIKE DOMAIN-CONTAINING PROTEIN SUSHI, NIDOGEN AND EGF LIKE DOMAINS 1 Notch signaling pathway#P00045>Notch#P01099;Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179 LEPOC|Ensembl=ENSLOCG00000014148.1|UniProtKB=W5N9X3 W5N9X3 PTHR25465:SF26 B-BOX DOMAIN CONTAINING FINTRIM FAMILY, MEMBER 84-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015202.1|UniProtKB=W5NDK0 W5NDK0 ANO4 PTHR12308:SF28 ANOCTAMIN ANOCTAMIN-4 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010187.1|UniProtKB=W5MVR6 W5MVR6 PTHR13803:SF1 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24A cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009765.1|UniProtKB=W5MU78 W5MU78 PTHR24278:SF26 COAGULATION FACTOR COAGULATION FACTOR VII extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 Blood coagulation#P00011>FVIIa#P00447;Angiogenesis#P00005>FVIIa#P00201;Blood coagulation#P00011>FVII#P00454 LEPOC|Ensembl=ENSLOCG00000000541.1|UniProtKB=W5LWU0 W5LWU0 PTHR14248:SF33 CYCLIN Y, ISOFORM A CYCLIN-Y protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 LEPOC|Ensembl=ENSLOCG00000005341.1|UniProtKB=W5MDH5 W5MDH5 PTHR11438:SF3 PROENKEPHALIN PROENKEPHALIN-A protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;cell body#GO:0044297;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 neuropeptide#PC00162;peptide hormone#PC00179 Enkephalin release#P05913>Enkephalin#P05976;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Opioid proenkephalin pathway#P05915>leu-Enkephalin#P05989;Opioid proenkephalin pathway#P05915>peptide F#P05987;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Opioid proenkephalin pathway#P05915>proenkephalin#P05995;Enkephalin release#P05913>preproenkephalin#G06045;Opioid proenkephalin pathway#P05915>peptide E#P05988;Opioid proenkephalin pathway#P05915>met-Enkephalin#P05992 LEPOC|Ensembl=ENSLOCG00000009981.1|UniProtKB=W5MV21 W5MV21 PTHR14102:SF12 PAR-6-RELATED CDNA SEQUENCE BC034090 establishment or maintenance of cell polarity#GO:0007163;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular anatomical structure#GO:0005622 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000010800.1|UniProtKB=W5MXY1 W5MXY1 ADAMTS5 PTHR13723:SF37 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015119.1|UniProtKB=W5ND98 W5ND98 FAR2 PTHR11011:SF120 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015053.1|UniProtKB=W5ND16 W5ND16 PTHR11699:SF131 ALDEHYDE DEHYDROGENASE-RELATED MITOCHONDRIAL 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000006044.1|UniProtKB=W5MFZ0 W5MFZ0 PTHR21435:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000011531.1|UniProtKB=W5N0K7 W5N0K7 PTHR19290:SF94 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014788.1|UniProtKB=W5NC54 W5NC54 PTHR15976:SF15 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011348.1|UniProtKB=W5MZY4 W5MZY4 PTHR33906:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000009394.1|UniProtKB=W5MSU4 W5MSU4 PTHR14557:SF3 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 1 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000009681.1|UniProtKB=W5MTX4 W5MTX4 PABPC3 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000653.1|UniProtKB=W5LX64 W5LX64 PTHR23104:SF15 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN CELL GROWTH REGULATOR WITH EF HAND DOMAIN PROTEIN 1 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008175.1|UniProtKB=W5MNG1 W5MNG1 PTHR47051:SF1 NESTIN NESTIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;positive regulation of organelle organization#GO:0010638;regulation of protein depolymerization#GO:1901879;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of protein-containing complex disassembly#GO:0043244;regulation of cellular component organization#GO:0051128;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008001.1|UniProtKB=W5MMW0 W5MMW0 PTHR11959:SF10 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005065.1|UniProtKB=W5MCI7 W5MCI7 PTHR34438:SF1 SI:DKEY-97L20.6 CHROMOSOME 2 OPEN READING FRAME 81 LEPOC|Ensembl=ENSLOCG00000006526.1|UniProtKB=W5MHM3 W5MHM3 PTHR10687:SF11 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 4 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cytoplasmic vesicle membrane#GO:0030659 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001482.1|UniProtKB=W5LZY9 W5LZY9 PTHR12984:SF15 SCY1-RELATED S/T PROTEIN KINASE-LIKE PROTEIN-ASSOCIATING WITH THE CARBOXYL-TERMINAL DOMAIN OF EZRIN non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008089.1|UniProtKB=W5MN62 W5MN62 PTHR24340:SF17 HOMEOBOX PROTEIN NKX NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005306.1|UniProtKB=W5MDE1 W5MDE1 PTHR14064:SF6 CHONDROMODULIN-RELATED LEUKOCYTE CELL-DERIVED CHEMOTAXIN 1 regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;negative regulation of angiogenesis#GO:0016525;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;negative regulation of cellular process#GO:0048523 LEPOC|Ensembl=ENSLOCG00000005937.1|UniProtKB=W5MFL0 W5MFL0 MTRF1 PTHR43804:SF1 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1, MITOCHONDRIAL protein-containing complex disassembly#GO:0032984;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;translational termination#GO:0006415;peptide biosynthetic process#GO:0043043;cellular component disassembly#GO:0022411;protein-containing complex organization#GO:0043933;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016399.1|UniProtKB=W5NHZ2 W5NHZ2 PTHR46680:SF5 NF-KAPPA-B INHIBITOR ALPHA NFKB INHIBITOR EPSILON NF-kappaB binding#GO:0051059;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 cellular localization#GO:0051641;response to cytokine#GO:0034097;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;protein localization#GO:0008104;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to tumor necrosis factor#GO:0034612;regulation of cellular biosynthetic process#GO:0031326;cellular macromolecule localization#GO:0070727;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;maintenance of location#GO:0051235;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016750.1|UniProtKB=W5NJ99 W5NJ99 PTHR18905:SF12 NINEIN NINEIN-LIKE PROTEIN microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 PDGF signaling pathway#P00047>GSK3#P01153 LEPOC|Ensembl=ENSLOCG00000007939.1|UniProtKB=W5MMN4 W5MMN4 PTHR19282:SF257 TETRASPANIN TETRASPANIN-7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005909.1|UniProtKB=W5MFH7 W5MFH7 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 translation initiation factor binding#GO:0031369;small molecule binding#GO:0036094;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;alcohol binding#GO:0043178 poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004824.1|UniProtKB=W5MBN2 W5MBN2 PTHR15729:SF14 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 33 ISOFORM X1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;Golgi apparatus#GO:0005794;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004809.1|UniProtKB=W5MBL6 W5MBL6 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011033.1|UniProtKB=W5MYS8 W5MYS8 PTHR11860:SF96 POLYMERIC-IMMUNOGLOBULIN RECEPTOR SUBFAMILY NOT NAMED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006032.1|UniProtKB=W5MFX3 W5MFX3 PTHR15468:SF7 ZNF185 SCIELLIN epidermis development#GO:0008544;tissue development#GO:0009888;anatomical structure development#GO:0048856;developmental process#GO:0032502 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002085.1|UniProtKB=W5M225 W5M225 PTHR11469:SF1 GLUCOSE-6-PHOSPHATE ISOMERASE GLUCOSE-6-PHOSPHATE ISOMERASE carbohydrate binding#GO:0030246;isomerase activity#GO:0016853;small molecule binding#GO:0036094;monosaccharide binding#GO:0048029;binding#GO:0005488;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;organophosphate catabolic process#GO:0046434;hexose biosynthetic process#GO:0019319;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674 LEPOC|Ensembl=ENSLOCG00000013000.1|UniProtKB=W5N5U9 W5N5U9 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000016490.1|UniProtKB=W5NIB0 W5NIB0 PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013751.1|UniProtKB=W5N8J8 W5N8J8 PTHR44974:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017974.1|UniProtKB=W5NN66 W5NN66 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000016595.1|UniProtKB=W5NIN7 W5NIN7 SCML4 PTHR12247:SF85 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001418.1|UniProtKB=W5LZQ8 W5LZQ8 PTHR47312:SF1 MELANOMA-DERIVED GROWTH REGULATORY PROTEIN MELANOMA-DERIVED GROWTH REGULATORY PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 LEPOC|Ensembl=ENSLOCG00000015195.1|UniProtKB=W5NDJ0 W5NDJ0 PTHR11711:SF41 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000007130.1|UniProtKB=W5MJS1 W5MJS1 PTHR18952:SF110 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 6 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000012262.1|UniProtKB=W5N377 W5N377 PTHR48482:SF3 INTERLEUKIN-19-RELATED INTERLEUKIN-19 LEPOC|Ensembl=ENSLOCG00000015725.1|UniProtKB=W5NFE9 W5NFE9 PTHR24064:SF432 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 2 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic cation transport#GO:0015695;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007047.1|UniProtKB=W5MJH0 W5MJH0 PTHR23194:SF7 PYGOPUS PYGOPUS HOMOLOG 2 Wnt signaling pathway#P00057>Pygo#P01464 LEPOC|Ensembl=ENSLOCG00000014116.1|UniProtKB=W5N9T8 W5N9T8 PTHR23101:SF58 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012086.1|UniProtKB=W5N2L8 W5N2L8 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002175.1|UniProtKB=W5M2C3 W5M2C3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010950.1|UniProtKB=W5MYH2 W5MYH2 PTHR40472:SF6 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012339.1|UniProtKB=W5N3I5 W5N3I5 PTHR18934:SF95 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000016195.1|UniProtKB=W5NH56 W5NH56 EIF3L PTHR13242:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009433.1|UniProtKB=W5MSZ9 W5MSZ9 PTHR10177:SF63 CYCLINS CYCLIN-J-LIKE PROTEIN protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000002518.1|UniProtKB=W5M3K6 W5M3K6 PTHR24418:SF39 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LCK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;hemopoiesis#GO:0030097;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;T cell differentiation#GO:0030217;cell activation#GO:0001775;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;lymphocyte differentiation#GO:0030098;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;T cell activation#GO:0042110;defense response to other organism#GO:0098542;leukocyte differentiation#GO:0002521;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;T cell activation#P00053>Lck#P01310 LEPOC|Ensembl=ENSLOCG00000015221.1|UniProtKB=W5NDM2 W5NDM2 PTHR24332:SF15 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014992.1|UniProtKB=W5NCV3 W5NCV3 PTHR10476:SF2 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1B-RELATED endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013322.1|UniProtKB=W5N709 W5N709 PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015608.1|UniProtKB=W5NF09 W5NF09 PTHR24264:SF42 TRYPSIN-RELATED TISSUE-TYPE PLASMINOGEN ACTIVATOR hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cell migration#GO:0016477;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 Plasminogen activating cascade#P00050>tPA#P01257;Blood coagulation#P00011>tPA#P00431;Plasminogen activating cascade#P00050>pro-tPA#P01249 LEPOC|Ensembl=ENSLOCG00000004443.1|UniProtKB=W5MA98 W5MA98 PTHR24388:SF37 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CCKR signaling map#P06959>SNAI1#P07055 LEPOC|Ensembl=ENSLOCG00000016544.1|UniProtKB=W5NIH2 W5NIH2 TMEM87B PTHR21229:SF16 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87B localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013446.1|UniProtKB=W5N7H1 W5N7H1 PTHR14445:SF37 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002041.1|UniProtKB=W5M1W4 W5M1W4 PTHR12422:SF2 GH09096P CYRIA_CYRIB RAC1 BINDING DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000233.1|UniProtKB=W5LVV0 W5LVV0 PTHR23226:SF377 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012433.1|UniProtKB=W5N3V4 W5N3V4 PTHR45700:SF2 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3C transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000000098.1|UniProtKB=W5LVF0 W5LVF0 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015130.1|UniProtKB=W5NDB3 W5NDB3 PTHR11817:SF101 PYRUVATE KINASE PYRUVATE KINASE PKM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;cellular response to hormone stimulus#GO:0032870;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;carbohydrate derivative catabolic process#GO:1901136;cellular response to organic substance#GO:0071310;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;response to nitrogen compound#GO:1901698;cellular response to organonitrogen compound#GO:0071417;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;organonitrogen compound catabolic process#GO:1901565;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to stimulus#GO:0050896;response to hormone#GO:0009725;aromatic compound catabolic process#GO:0019439;response to chemical#GO:0042221;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 LEPOC|Ensembl=ENSLOCG00000005506.1|UniProtKB=W5ME42 W5ME42 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 LEPOC|Ensembl=ENSLOCG00000002447.1|UniProtKB=W5M3C0 W5M3C0 PTHR25465:SF35 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003919.1|UniProtKB=W5M8I0 W5M8I0 PTHR24418:SF399 TYROSINE-PROTEIN KINASE MEGAKARYOCYTE-ASSOCIATED TYROSINE-PROTEIN KINASE protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000000019.1|UniProtKB=W5LV63 W5LV63 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000016378.1|UniProtKB=W5NHX0 W5NHX0 PTHR10151:SF77 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 1 pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;exonuclease activity#GO:0004527;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;transport#GO:0006810;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;inorganic anion transport#GO:0015698;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;regulation of multicellular organismal process#GO:0051239;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound metabolic process#GO:1901564;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;localization#GO:0051179;aromatic compound catabolic process#GO:0019439;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012534.1|UniProtKB=W5N477 W5N477 PTHR19282:SF39 TETRASPANIN LEUKOCYTE SURFACE ANTIGEN CD53 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007169.1|UniProtKB=W5MJX8 W5MJX8 PTHR36498:SF1 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 LEPOC|Ensembl=ENSLOCG00000015131.1|UniProtKB=W5NDB5 W5NDB5 PTHR23065:SF14 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008463.1|UniProtKB=W5MPJ2 W5MPJ2 PTHR24035:SF136 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 10 localization#GO:0051179;establishment of localization#GO:0051234;phagocytosis#GO:0006909;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014797.1|UniProtKB=W5NCA6 W5NCA6 PTHR11254:SF67 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HUWE1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000013746.1|UniProtKB=W5N8J3 W5N8J3 PTHR24237:SF14 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006892.1|UniProtKB=W5MIX4 W5MIX4 PTHR12015:SF165 SMALL INDUCIBLE CYTOKINE A CHEMOKINE (C-C MOTIF) LIGAND 34A, DUPLICATE 4-RELATED cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012821.1|UniProtKB=W5N567 W5N567 CDH18 PTHR24027:SF106 CADHERIN-23 CADHERIN-18 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000009784.1|UniProtKB=W5MU93 W5MU93 PTHR45688:SF6 FAMILY NOT NAMED 5-PHOSPHOHYDROXY-L-LYSINE PHOSPHO-LYASE cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015946.1|UniProtKB=W5NG77 W5NG77 PTHR21780:SF0 TRANSMEMBRANE PROTEIN 209 TRANSMEMBRANE PROTEIN 209 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001986.1|UniProtKB=W5M1W3 W5M1W3 PTHR14226:SF23 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004244.1|UniProtKB=W5M9L5 W5M9L5 PTHR47440:SF1 RIKEN CDNA A430078G23 GENE RHO_RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR 18 LEPOC|Ensembl=ENSLOCG00000011567.1|UniProtKB=W5N0Q0 W5N0Q0 DCK PTHR10513:SF19 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000013848.1|UniProtKB=W5N8X0 W5N8X0 PTHR47577:SF1 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000004132.1|UniProtKB=W5M980 W5M980 PTHR20859:SF85 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA_BETA RECEPTOR 1 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009079.1|UniProtKB=W5MRQ6 W5MRQ6 PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005144.1|UniProtKB=W5MCT4 W5MCT4 PTHR12234:SF1 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMINOTRANSFERASE N-TERMINAL SUBDOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010296.1|UniProtKB=W5MW50 W5MW50 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000017615.1|UniProtKB=W5NM61 W5NM61 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018027.1|UniProtKB=W5NNB9 W5NNB9 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR ODORANT RECEPTOR-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005485.1|UniProtKB=W5ME21 W5ME21 PTHR23159:SF63 CENTROSOMAL PROTEIN 2 CILIARY ROOTLET COILED-COIL, ROOTLETIN FAMILY MEMBER 2 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002821.1|UniProtKB=W5M4L1 W5M4L1 PTHR44699:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11-LIKE defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013665.1|UniProtKB=W5N888 W5N888 PTHR12489:SF14 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 4 PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811 postsynapse organization#GO:0099173;localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;sensory perception of sound#GO:0007605;system process#GO:0003008;cellular component organization#GO:0016043;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;receptor clustering#GO:0043113 synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017690.1|UniProtKB=W5NMD6 W5NMD6 PTHR40472:SF8 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 2 LEPOC|Ensembl=ENSLOCG00000014758.1|UniProtKB=W5NC12 W5NC12 PTHR45951:SF2 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000138.1|UniProtKB=W5LVJ6 W5LVJ6 PTHR17901:SF14 MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1 MAGNESIUM-DEPENDENT PHOSPHATASE 1 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000018009.1|UniProtKB=W5NNA1 W5NNA1 PTHR15065:SF5 INSULINOMA-ASSOCIATED 1 INSULINOMA-ASSOCIATED PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014312.1|UniProtKB=W5NAG3 W5NAG3 PTHR13622:SF8 THIAMIN PYROPHOSPHOKINASE THIAMIN PYROPHOSPHOKINASE 1 kinase#PC00137 Thiamin metabolism#P02780>Thiamine kinase#P03176 LEPOC|Ensembl=ENSLOCG00000013394.1|UniProtKB=W5N7A8 W5N7A8 PTHR14894:SF0 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cellular process#GO:0050794 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000006714.1|UniProtKB=W5MIA1 W5MIA1 PTHR24072:SF120 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000010754.1|UniProtKB=W5MXR9 W5MXR9 PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000010025.1|UniProtKB=W5MV56 W5MV56 PTHR11808:SF15 TRANS-SULFURATION ENZYME FAMILY MEMBER CYSTATHIONINE GAMMA-LYASE small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lyase#PC00144 Methionine biosynthesis#P02753>O-Succinyl homoserine lyase#P03026 LEPOC|Ensembl=ENSLOCG00000010002.1|UniProtKB=W5MV28 W5MV28 PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 LEPOC|Ensembl=ENSLOCG00000017349.1|UniProtKB=W5NLE5 W5NLE5 PTHR24394:SF18 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 18 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018312.1|UniProtKB=W5NP54 W5NP54 PTHR45617:SF94 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005871.1|UniProtKB=W5MFD0 W5MFD0 PTHR10131:SF94 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016344.1|UniProtKB=W5NHS0 W5NHS0 PTHR15286:SF10 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018239.1|UniProtKB=W5NNY1 W5NNY1 C10orf105 PTHR38325:SF1 MCG55969 GENE, 17455-RELATED LEPOC|Ensembl=ENSLOCG00000006302.1|UniProtKB=W5MGV1 W5MGV1 PTHR21245:SF8 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN APOBEC1 COMPLEMENTATION FACTOR nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003030.1|UniProtKB=W5M5B5 W5M5B5 PTHR24355:SF18 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750;Parkinson disease#P00049>GRK#P01234 LEPOC|Ensembl=ENSLOCG00000016665.1|UniProtKB=W5NIX6 W5NIX6 PTHR31909:SF2 CHROMOSOME 20 ORF85 FAMILY MEMBER RIKEN CDNA 2410004P03 GENE LEPOC|Ensembl=ENSLOCG00000008503.1|UniProtKB=W5MPP3 W5MPP3 PTHR11097:SF9 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP43 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;snRNA processing#GO:0016180;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;exosome (RNase complex)#GO:0000178 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000014281.1|UniProtKB=W5NAC3 W5NAC3 PTHR11769:SF19 HYALURONIDASE HYALURONIDASE-3 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;secretory vesicle#GO:0099503;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002906.1|UniProtKB=W5M4X4 W5M4X4 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012139.1|UniProtKB=W5N2S8 W5N2S8 PTHR11532:SF80 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE N CATALYTIC CHAIN metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016088.1|UniProtKB=W5NGR3 W5NGR3 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000005921.1|UniProtKB=W5MFJ1 W5MFJ1 PTHR33820:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000002890.1|UniProtKB=W5M4T9 W5M4T9 UNC119B PTHR12951:SF3 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG B lipid binding#GO:0008289;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;system development#GO:0048731;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;anatomical structure development#GO:0048856;protein transport#GO:0015031;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001460.1|UniProtKB=W5LZY2 W5LZY2 PTHR24211:SF15 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008314.1|UniProtKB=W5MNZ1 W5MNZ1 PTHR10006:SF19 MUCIN-1-RELATED MUCIN-1 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010677.1|UniProtKB=W5MXG8 W5MXG8 PTHR10177:SF59 CYCLINS CYCLIN-G1 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin G#P04662;p53 pathway feedback loops 2#P04398>CYCLIN G#G04715;p53 pathway#P00059>Cyclin G#G04689 LEPOC|Ensembl=ENSLOCG00000003447.1|UniProtKB=W5M6T0 W5M6T0 PTHR24208:SF117 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;central nervous system neuron differentiation#GO:0021953;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;forebrain development#GO:0030900;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008176.1|UniProtKB=W5MNG4 W5MNG4 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;organic hydroxy compound metabolic process#GO:1901615;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;glycosylation#GO:0070085;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008746.1|UniProtKB=W5MQI9 W5MQI9 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009141.1|UniProtKB=W5MRY5 W5MRY5 PTHR11346:SF104 GALECTIN GALECTIN-2 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014245.1|UniProtKB=W5NA79 W5NA79 PTHR46197:SF1 PROTEIN ABHD14B-LIKE PROTEIN ABHD14A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009500.1|UniProtKB=W5MT95 W5MT95 PTHR12907:SF28 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN3 cation binding#GO:0043169;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 response to hypoxia#GO:0001666;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein hydroxylation#GO:0018126;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to oxygen levels#GO:0070482;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 LEPOC|Ensembl=ENSLOCG00000011770.1|UniProtKB=W5N1H0 W5N1H0 PTHR12103:SF17 5'-NUCLEOTIDASE DOMAIN-CONTAINING CYTOSOLIC PURINE 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009215.1|UniProtKB=W5MS81 W5MS81 PTHR12027:SF75 WNT RELATED PROTEIN WNT-9A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000013296.1|UniProtKB=W5N6X5 W5N6X5 PTHR10615:SF161 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;N-acyltransferase activity#GO:0016410;molecular adaptor activity#GO:0060090;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 LEPOC|Ensembl=ENSLOCG00000017115.1|UniProtKB=W5NKJ0 W5NKJ0 PTHR22802:SF460 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016297.1|UniProtKB=W5NHK8 W5NHK8 PTHR48099:SF12 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED MONOFUNCTIONAL C1-TETRAHYDROFOLATE SYNTHASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 LEPOC|Ensembl=ENSLOCG00000016664.1|UniProtKB=W5NIX8 W5NIX8 RAD51AP1 PTHR15361:SF4 RAD51/NUKS-INTERACTING PROTEIN RAD51-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000001429.1|UniProtKB=W5LZS1 W5LZS1 CMTM6 PTHR22776:SF25 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 6 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010149.1|UniProtKB=W5MVL5 W5MVL5 PTHR20583:SF1 TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN TRIPLE QXXK_R MOTIF-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005654.1|UniProtKB=W5MEL8 W5MEL8 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000015814.1|UniProtKB=W5NFR3 W5NFR3 PTHR46513:SF6 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED NIDOGEN-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010122.1|UniProtKB=W5MVI2 W5MVI2 PTHR13098:SF3 WOLFRAMIN WOLFRAMIN response to organic substance#GO:0010033;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;calcium ion homeostasis#GO:0055074;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cell communication#GO:0007154;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002280.1|UniProtKB=W5M2R0 W5M2R0 PTHR48021:SF18 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 8 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006694.1|UniProtKB=W5MI78 W5MI78 PTHR19282:SF214 TETRASPANIN CD81 ANTIGEN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016548.1|UniProtKB=W5NII1 W5NII1 PTHR13119:SF22 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 6 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004659.1|UniProtKB=W5MB18 W5MB18 PTHR18966:SF351 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 5 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;sodium channel activity#GO:0005272;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054;Ionotropic glutamate receptor pathway#P00037>KA5#P01000 LEPOC|Ensembl=ENSLOCG00000001066.1|UniProtKB=W5LYJ4 W5LYJ4 PTHR13017:SF0 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000004648.1|UniProtKB=W5MB05 W5MB05 PTHR13059:SF13 HMG-BOX TRANSCRIPTION FACTOR BBX PROTEIN CAPICUA HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000008062.1|UniProtKB=W5MN33 W5MN33 PTHR13976:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003089.1|UniProtKB=W5M5H9 W5M5H9 PTHR15407:SF28 FUKUTIN-RELATED RIBITOL-5-PHOSPHATE TRANSFERASE FKTN glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000018248.1|UniProtKB=W5NNZ0 W5NNZ0 PTHR28615:SF1 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA1 protein kinase regulator activity#GO:0019887;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;protein kinase binding#GO:0019901;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase binding#GO:0019900 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013202.1|UniProtKB=W5N6K1 W5N6K1 PTHR23318:SF3 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013217.1|UniProtKB=W5N6M5 W5N6M5 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006524.1|UniProtKB=W5MHM9 W5MHM9 PTHR15116:SF14 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000000843.1|UniProtKB=W5LXT7 W5LXT7 PTHR23291:SF35 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 3 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007038.1|UniProtKB=W5MJG2 W5MJG2 PTHR10865:SF24 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010091.1|UniProtKB=W5MVE2 W5MVE2 PTHR23345:SF9 VITELLOGENIN-RELATED VITELLOGENIN-RELATED transporter activity#GO:0005215;lipid transporter activity#GO:0005319 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cellular process#GO:0009987;response to estradiol#GO:0032355 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000005442.1|UniProtKB=W5MDU6 W5MDU6 PTHR24106:SF286 NACHT, LRR AND CARD DOMAINS-CONTAINING NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 3-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004032.1|UniProtKB=W5M8W0 W5M8W0 PTHR15116:SF15 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005295.1|UniProtKB=W5MDE0 W5MDE0 PTHR12767:SF11 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER A LEPOC|Ensembl=ENSLOCG00000009742.1|UniProtKB=W5MU41 W5MU41 PTHR34923:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 20 SMALL INTEGRAL MEMBRANE PROTEIN 20 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009965.1|UniProtKB=W5MUZ4 W5MUZ4 PTHR11801:SF18 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA_BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to biotic stimulus#GO:0009607;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;defense response#GO:0006952;signaling#GO:0023052;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;defense response to symbiont#GO:0140546;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to hormone#GO:0009725;response to stress#GO:0006950;receptor signaling pathway via STAT#GO:0097696;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;type I interferon-mediated signaling pathway#GO:0060337;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 p53 pathway feedback loops 2#P04398>Myc#P04649;PDGF signaling pathway#P00047>STAT#P01173;Oxidative stress response#P00046>Stat1#P01125;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027;Oxidative stress response#P00046>Myc#P01124;Ras Pathway#P04393>Stat 1/3#P04566;Interferon-gamma signaling pathway#P00035>STAT1#P00961;Angiogenesis#P00005>STAT1#P00218;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 LEPOC|Ensembl=ENSLOCG00000015321.1|UniProtKB=W5NDZ2 W5NDZ2 PTHR19338:SF4 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT LEPOC|Ensembl=ENSLOCG00000000276.1|UniProtKB=W5LVZ5 W5LVZ5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000018144.1|UniProtKB=W5NNN6 W5NNN6 PTHR10666:SF454 UBIQUITIN ISG15 UBIQUITIN-LIKE MODIFIER nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012271.1|UniProtKB=W5N388 W5N388 PTHR21230:SF1 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle fusion#GO:0006906;membrane fusion#GO:0061025;establishment of localization#GO:0051234;membrane organization#GO:0061024;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;membrane#GO:0016020;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000002920.1|UniProtKB=W5M4Z9 W5M4Z9 PTHR24278:SF33 COAGULATION FACTOR PROTEIN Z, VITAMIN K-DEPENDENT PLASMA GLYCOPROTEIN A extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000739.1|UniProtKB=W5LXG6 W5LXG6 PTHR47027:SF29 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016149.1|UniProtKB=W5NGZ0 W5NGZ0 PTHR24060:SF29 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Endogenous cannabinoid signaling#P05730>mGluR#P05748;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000004857.1|UniProtKB=W5MBU1 W5MBU1 PTHR11474:SF4 TYROSINASE FAMILY MEMBER L-DOPACHROME TAUTOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 secondary metabolic process#GO:0019748;pigmentation#GO:0043473;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;nervous system development#GO:0007399;regulation of biological process#GO:0050789;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;central nervous system development#GO:0007417;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;regulation of multicellular organismal process#GO:0051239;cellular metabolic process#GO:0044237;pigment metabolic process#GO:0042440;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;forebrain development#GO:0030900;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;positive regulation of multicellular organismal process#GO:0051240;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;cell division#GO:0051301;tyrosine metabolic process#GO:0006570;animal organ development#GO:0048513;developmental process#GO:0032502;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;developmental pigmentation#GO:0048066;organic cyclic compound metabolic process#GO:1901360;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;regulation of cell population proliferation#GO:0042127;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of nervous system development#GO:0051962;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;secondary metabolite biosynthetic process#GO:0044550;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;generation of neurons#GO:0048699;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011437.1|UniProtKB=W5N0A0 W5N0A0 PTHR11073:SF11 CALRETICULIN AND CALNEXIN CALNEXIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;ERAD pathway#GO:0036503;cellular biosynthetic process#GO:0044249;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003785.1|UniProtKB=W5M809 W5M809 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013435.1|UniProtKB=W5N7F6 W5N7F6 PTHR47992:SF119 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1K, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012473.1|UniProtKB=W5N408 W5N408 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011122.1|UniProtKB=W5MZ55 W5MZ55 PTHR14700:SF0 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;multicellular organismal process#GO:0032501;mitochondrion organization#GO:0007005;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006246.1|UniProtKB=W5MGP0 W5MGP0 PTHR47965:SF69 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 1 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;membrane protein ectodomain proteolysis#GO:0006509;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101;Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178;Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094 LEPOC|Ensembl=ENSLOCG00000004766.1|UniProtKB=W5MBG2 W5MBG2 PTHR43128:SF2 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007432.1|UniProtKB=W5MKV2 W5MKV2 PTHR23068:SF6 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2B membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000011655.1|UniProtKB=W5N113 W5N113 PTHR24393:SF157 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010871.1|UniProtKB=W5MY69 W5MY69 PTHR16276:SF1 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3 SMALL RIBOSOMAL SUBUNIT PROTEIN MS39 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;rRNA binding#GO:0019843 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006322.1|UniProtKB=W5MGX2 W5MGX2 KCTD1 PTHR21446:SF12 DUF3504 DOMAIN-CONTAINING PROTEIN POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000013831.1|UniProtKB=W5N8V5 W5N8V5 PTHR14456:SF2 INOSITOL POLYPHOSPHATE KINASE 1 INOSITOL-PENTAKISPHOSPHATE 2-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017361.1|UniProtKB=W5NLF7 W5NLF7 PTHR16277:SF10 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012202.1|UniProtKB=W5N311 W5N311 PTHR16004:SF3 RING FINGER PROTEIN 31-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF31 acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;modification-dependent protein binding#GO:0140030;transferase activity#GO:0016740;ubiquitin-like protein binding#GO:0032182;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;ubiquitin protein ligase activity#GO:0061630;ubiquitin binding#GO:0043130;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;polyubiquitin modification-dependent protein binding#GO:0031593 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008869.1|UniProtKB=W5MQY4 W5MQY4 PTHR46909:SF1 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL36M membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017702.1|UniProtKB=W5NME8 W5NME8 PTHR46617:SF5 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016383.1|UniProtKB=W5NHX4 W5NHX4 PTHR11003:SF138 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413;Opioid proenkephalin pathway#P05915>K+ channel#P05990;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425 LEPOC|Ensembl=ENSLOCG00000014490.1|UniProtKB=W5NB22 W5NB22 PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002547.1|UniProtKB=W5M3N3 W5M3N3 PTHR45929:SF1 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN-RELATED endosomal transport#GO:0016197;cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006580.1|UniProtKB=W5MHU7 W5MHU7 PTHR10033:SF15 CALSEQUESTRIN CALSEQUESTRIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;calcium-mediated signaling#GO:0019722;regulation of heart contraction#GO:0008016;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of metal ion transport#GO:0010959;regulation of sequestering of calcium ion#GO:0051282;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;cell communication#GO:0007154;cellular process#GO:0009987;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;sarcoplasmic reticulum#GO:0016529;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;intracellular organelle lumen#GO:0070013;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;endoplasmic reticulum#GO:0005783;I band#GO:0031674 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000005815.1|UniProtKB=W5MF65 W5MF65 PTHR11620:SF2 60S RIBOSOMAL PROTEIN L23A 60S RIBOSOMAL PROTEIN L23A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013725.1|UniProtKB=W5N8G2 W5N8G2 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000013071.1|UniProtKB=W5N643 W5N643 PTHR11614:SF87 PHOSPHOLIPASE-RELATED MONOGLYCERIDE LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006534.1|UniProtKB=W5MHN7 W5MHN7 PTHR47958:SF10 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX39A catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;cellular localization#GO:0051641;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;organic substance transport#GO:0071702;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA transport#GO:0051028;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleobase-containing compound transport#GO:0015931;mRNA processing#GO:0006397;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA splicing, via transesterification reactions#GO:0000375;RNA export from nucleus#GO:0006405 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000001684.1|UniProtKB=W5M0M9 W5M0M9 PTHR11967:SF2 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001616.1|UniProtKB=W5M0E9 W5M0E9 PTHR13814:SF10 FETUIN FETUIN-B peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000005593.1|UniProtKB=W5MEE2 W5MEE2 F2RL1 PTHR24232:SF106 G-PROTEIN COUPLED RECEPTOR COAGULATION FACTOR II (THROMBIN) RECEPTOR-LIKE 1 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013401.1|UniProtKB=W5N7A9 W5N7A9 PTHR23268:SF124 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010469.1|UniProtKB=W5MWS1 W5MWS1 CFAP20DC PTHR12458:SF7 ORF PROTEIN PROTEIN CFAP20DC LEPOC|Ensembl=ENSLOCG00000006741.1|UniProtKB=W5MID0 W5MID0 PTHR31305:SF2 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 lysosome organization#GO:0007040;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;regulation of neurotransmitter secretion#GO:0046928;lysosomal transport#GO:0007041;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;lysosome localization#GO:0032418;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;vacuolar transport#GO:0007034;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000006571.1|UniProtKB=W5MHS6 W5MHS6 PTHR12451:SF0 TRANSCRIPTION FACTOR CASTOR PROTEIN MING -RELATED ZINC FINGER PROTEIN CASTOR HOMOLOG 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011911.1|UniProtKB=W5N210 W5N210 PTHR24023:SF912 COLLAGEN ALPHA COLLAGEN ALPHA-1(XV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000010920.1|UniProtKB=W5MYD2 W5MYD2 PTHR24248:SF0 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2DA ADRENERGIC RECEPTOR-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011274.1|UniProtKB=W5MZQ0 W5MZQ0 PTHR12577:SF14 DACHSHUND DACHSHUND HOMOLOG 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000006588.1|UniProtKB=W5MHU9 W5MHU9 PTHR35193:SF5 MUCIN 13A, CELL SURFACE-ASSOCIATED-RELATED FLOCCULATION PROTEIN FLO11 LEPOC|Ensembl=ENSLOCG00000016873.1|UniProtKB=W5NJP9 W5NJP9 PTHR24340:SF40 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016499.1|UniProtKB=W5NIC3 W5NIC3 PTHR10582:SF33 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CHANNEL PYREXIA calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001218.1|UniProtKB=W5LZ25 W5LZ25 PTHR42758:SF1 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000011034.1|UniProtKB=W5MYT0 W5MYT0 PTHR22803:SF151 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE LECTIN DOMAIN FAMILY 19 MEMBER A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013121.1|UniProtKB=W5N6A6 W5N6A6 PTHR23077:SF194 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG B pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;proteasomal protein catabolic process#GO:0010498;autophagosome maturation#GO:0097352;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;microtubule-based process#GO:0007017;response to chemical#GO:0042221;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001404.1|UniProtKB=W5LZP4 W5LZP4 PTHR19325:SF493 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING E-SELECTIN complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000003274.1|UniProtKB=W5M665 W5M665 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002405.1|UniProtKB=W5M366 W5M366 PTHR48105:SF21 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 2, MITOCHONDRIAL protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003043.1|UniProtKB=W5M5D6 W5M5D6 PTHR15934:SF4 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008952.1|UniProtKB=W5MR98 W5MR98 PTHR13906:SF6 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012316.1|UniProtKB=W5N3E5 W5N3E5 PTHR19443:SF84 HEXOKINASE PHOSPHOTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;intracellular chemical homeostasis#GO:0055082;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;organophosphate catabolic process#GO:0046434;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate phosphorylation#GO:0046835;organonitrogen compound metabolic process#GO:1901564;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;intracellular glucose homeostasis#GO:0001678;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000005915.1|UniProtKB=W5MFI9 W5MFI9 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003799.1|UniProtKB=W5M824 W5M824 PTHR43917:SF10 FAMILY NOT NAMED GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005494.1|UniProtKB=W5ME25 W5ME25 PTHR24125:SF1 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1B LEPOC|Ensembl=ENSLOCG00000003017.1|UniProtKB=W5M5A7 W5M5A7 PTHR10896:SF21 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012160.1|UniProtKB=W5N2U6 W5N2U6 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>Calcineurin#P01446 LEPOC|Ensembl=ENSLOCG00000004390.1|UniProtKB=W5MA46 W5MA46 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017672.1|UniProtKB=W5NMB8 W5NMB8 PTHR32341:SF10 INTERFERON-INDUCIBLE GTPASE INTERFERON-INDUCIBLE GTPASE 5 LEPOC|Ensembl=ENSLOCG00000008396.1|UniProtKB=W5MP93 W5MP93 PTHR19331:SF487 SCAVENGER RECEPTOR DOMAIN-CONTAINING SOLUBLE SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SSC5D serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012677.1|UniProtKB=W5N4Q5 W5N4Q5 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;localization within membrane#GO:0051668;establishment of RNA localization#GO:0051236;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;chromosome organization#GO:0051276;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009388.1|UniProtKB=W5MSV7 W5MSV7 PTHR23322:SF96 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 1 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 LEPOC|Ensembl=ENSLOCG00000009454.1|UniProtKB=W5MT75 W5MT75 COL4A3 PTHR24023:SF891 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000010150.1|UniProtKB=W5MVL6 W5MVL6 KLHL12 PTHR24412:SF494 KELCH PROTEIN KELCH-LIKE PROTEIN 12 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011948.1|UniProtKB=W5N232 W5N232 PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 LEPOC|Ensembl=ENSLOCG00000006329.1|UniProtKB=W5MGX7 W5MGX7 PTHR13929:SF0 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012336.1|UniProtKB=W5N3H4 W5N3H4 PTHR15422:SF9 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D1-RELATED LEPOC|Ensembl=ENSLOCG00000008854.1|UniProtKB=W5MQW0 W5MQW0 PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004421.1|UniProtKB=W5MA77 W5MA77 PTHR10048:SF33 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;CCKR signaling map#P06959>p110#P07020;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;PI3 kinase pathway#P00048>p110#P01192;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Interleukin signaling pathway#P00036>PI3K#P00990;PI3 kinase pathway#P00048>P110ACT#P01177 LEPOC|Ensembl=ENSLOCG00000011407.1|UniProtKB=W5N063 W5N063 PTHR24028:SF42 CADHERIN-87A PROTOCADHERIN-12 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000007914.1|UniProtKB=W5MMK2 W5MMK2 PTHR45622:SF75 UBIQUITIN-PROTEIN LIGASE E3A-RELATED X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;system process#GO:0003008;transport#GO:0006810;microtubule-based movement#GO:0007018;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;visual perception#GO:0007601;post-translational protein modification#GO:0043687;plasma membrane bounded cell projection organization#GO:0120036;modification-dependent macromolecule catabolic process#GO:0043632;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cytoskeleton-dependent intracellular transport#GO:0030705;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;nervous system process#GO:0050877;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;sensory perception#GO:0007600;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014378.1|UniProtKB=W5NAP4 W5NAP4 PTHR15583:SF17 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR D ISOFORM X1 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004764.1|UniProtKB=W5MBF7 W5MBF7 SLC30A2 PTHR11562:SF51 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;response to stimulus#GO:0050896;metal ion transport#GO:0030001;response to chemical#GO:0042221;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012487.1|UniProtKB=W5N409 W5N409 PTHR11889:SF36 HEDGEHOG SONIC HEDGEHOG PROTEIN cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;developmental process#GO:0032502;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 LEPOC|Ensembl=ENSLOCG00000016201.1|UniProtKB=W5NH62 W5NH62 BEST3 PTHR10736:SF2 BESTROPHIN BESTROPHIN-3 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016887.1|UniProtKB=W5NJR5 W5NJR5 CFAP61 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014458.1|UniProtKB=W5NAZ7 W5NAZ7 PTHR10606:SF14 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;sugar-phosphatase activity#GO:0050308;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016031.1|UniProtKB=W5NGI8 W5NGI8 PTHR10824:SF36 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 17-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000008764.1|UniProtKB=W5MQL0 W5MQL0 PTHR11006:SF60 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 9 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;protein metabolic process#GO:0019538;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001097.1|UniProtKB=W5LYN4 W5LYN4 PTHR32428:SF3 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;TORC2 signaling#GO:0038203;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000016120.1|UniProtKB=W5NGV3 W5NGV3 PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003877.1|UniProtKB=W5M8C0 W5M8C0 PTHR22576:SF27 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE PARACASPASE 2 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003375.1|UniProtKB=W5M6J3 W5M6J3 PTHR43981:SF9 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015341.1|UniProtKB=W5NE17 W5NE17 PTHR15351:SF4 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-2 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 regulation of biological process#GO:0050789;SREBP signaling pathway#GO:0032933;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002873.1|UniProtKB=W5M4S2 W5M4S2 PTHR10910:SF103 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;RNA binding#GO:0003723;tRNA-specific adenosine deaminase activity#GO:0008251;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;adenosine to inosine editing#GO:0006382;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001799.1|UniProtKB=W5M126 W5M126 PTHR14469:SF0 SARCOMA ANTIGEN NY-SAR-23 FAMILY WITH SEQUENCE SIMILARITY 113 LEPOC|Ensembl=ENSLOCG00000015871.1|UniProtKB=W5NFY8 W5NFY8 PTHR11405:SF5 CARBAMOYLTRANSFERASE FAMILY MEMBER CAD PROTEIN ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 LEPOC|Ensembl=ENSLOCG00000011381.1|UniProtKB=W5N051 W5N051 PTHR22948:SF18 TUDOR DOMAIN CONTAINING PROTEIN TUDOR AND KH DOMAIN-CONTAINING PROTEIN negative regulation of gene expression#GO:0010629;male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;regulatory ncRNA processing#GO:0070918;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;piRNA processing#GO:0034587;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;multicellular organism development#GO:0007275;regionalization#GO:0003002;oogenesis#GO:0048477;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016213.1|UniProtKB=W5NH80 W5NH80 PDE7B PTHR11347:SF72 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000007545.1|UniProtKB=W5ML93 W5ML93 PTHR23292:SF35 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LITAF DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000772.1|UniProtKB=W5LXJ5 W5LXJ5 PTHR12713:SF11 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;active monoatomic ion transmembrane transporter activity#GO:0022853;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003395.1|UniProtKB=W5M6P7 W5M6P7 PTHR11973:SF18 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CELL SURFACE GLYCOPROTEIN MUC18 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012649.1|UniProtKB=W5N4L1 W5N4L1 PTHR16046:SF9 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000013760.1|UniProtKB=W5N8L2 W5N8L2 PTHR12210:SF173 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004747.1|UniProtKB=W5MBD3 W5MBD3 PTHR32251:SF17 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010962.1|UniProtKB=W5MYJ1 W5MYJ1 PTHR10985:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 40 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of multicellular organismal process#GO:0051239;circadian rhythm#GO:0007623;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;circadian regulation of gene expression#GO:0032922;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002231.1|UniProtKB=W5M2K5 W5M2K5 PTHR12622:SF21 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX2-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015585.1|UniProtKB=W5NEX8 W5NEX8 PTHR24223:SF19 ATP-BINDING CASSETTE SUB-FAMILY C CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 transmembrane transport#GO:0055085;organic anion transport#GO:0015711;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transmembrane transport#GO:0098661;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;intracellular anatomical structure#GO:0005622;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006944.1|UniProtKB=W5MJ47 W5MJ47 PTHR15067:SF5 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE AMFR transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010942.1|UniProtKB=W5MYG2 W5MYG2 PTHR24333:SF13 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX DOMAIN-CONTAINING PROTEIN homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014618.1|UniProtKB=W5NBI3 W5NBI3 PTHR16705:SF5 COMPLEXIN COMPLEXIN-3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;SNARE complex#GO:0031201;cell junction#GO:0030054;terminal bouton#GO:0043195;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000008397.1|UniProtKB=W5MP98 W5MP98 PTHR24072:SF105 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (RHO FAMILY, SMALL GTP BINDING PROTEIN RAC1) GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;Rac protein signal transduction#GO:0016601;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;intracellular signaling cassette#GO:0141124;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;establishment or maintenance of cell polarity#GO:0007163;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;regulation of leukocyte migration#GO:0002685;neuron differentiation#GO:0030182;regulation of actin cytoskeleton organization#GO:0032956;regulation of immune system process#GO:0002682;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell chemotaxis#GO:0060326;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;motor neuron axon guidance#GO:0008045;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;generation of neurons#GO:0048699;cell migration#GO:0016477 synapse#GO:0045202;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;postsynapse#GO:0098794;cell projection#GO:0042995;cytoskeleton#GO:0005856;dendritic spine#GO:0043197 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;p38 MAPK pathway#P05918>Rac#P06021;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;B cell activation#P00010>Rac#P00385;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 LEPOC|Ensembl=ENSLOCG00000007842.1|UniProtKB=W5MMA7 W5MMA7 PTHR22624:SF36 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4D cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;mitophagy#GO:0000423;protein modification process#GO:0036211;gene expression#GO:0010467;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009599.1|UniProtKB=W5MTL7 W5MTL7 PTHR12925:SF0 HIKESHI FAMILY MEMBER PROTEIN HIKESHI cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008770.1|UniProtKB=W5MQM3 W5MQM3 PTHR12305:SF60 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>PTEN#P00824;p53 pathway#P00059>PTEN#G01579;p53 pathway feedback loops 2#P04398>PTEN#P04658;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480 LEPOC|Ensembl=ENSLOCG00000011238.1|UniProtKB=W5MZJ9 W5MZJ9 HACD4 PTHR11035:SF16 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000009873.1|UniProtKB=W5MUL3 W5MUL3 PTHR11686:SF19 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 5 PROENZYME hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound catabolic process#GO:1901565;peptide catabolic process#GO:0043171;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glutathione metabolic process#GO:0006749;inflammatory response#GO:0006954;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;defense response#GO:0006952;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;response to stimulus#GO:0050896;sulfur compound catabolic process#GO:0044273;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008224.1|UniProtKB=W5MNN4 W5MNN4 PTHR15592:SF16 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002342.1|UniProtKB=W5M2Y2 W5M2Y2 PTHR14409:SF0 MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN PROTEIN MANBAL LEPOC|Ensembl=ENSLOCG00000004970.1|UniProtKB=W5MC71 W5MC71 PTHR24373:SF262 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001343.1|UniProtKB=W5LZG3 W5LZG3 PTHR10129:SF26 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFK sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000005861.1|UniProtKB=W5MFB7 W5MFB7 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 LEPOC|Ensembl=ENSLOCG00000012934.1|UniProtKB=W5N5M7 W5N5M7 PTHR24417:SF0 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 head development#GO:0060322;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;brain development#GO:0007420;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;nervous system development#GO:0007399;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;peptidyl-tyrosine modification#GO:0018212;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013996.1|UniProtKB=W5N9E4 W5N9E4 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;organelle fission#GO:0048285;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;peroxisome organization#GO:0007031;autophagy#GO:0006914;mitochondrial fission#GO:0000266;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000015442.1|UniProtKB=W5NEE8 W5NEE8 PTHR21678:SF6 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 R3H AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010033.1|UniProtKB=W5MV58 W5MV58 TRAPPC2B PTHR12403:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000969.1|UniProtKB=W5LY97 W5LY97 PTHR15680:SF9 RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015497.1|UniProtKB=W5NEL4 W5NEL4 PTHR11371:SF11 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000000294.1|UniProtKB=W5LW17 W5LW17 PTHR44324:SF4 WD40 REPEAT DOMAIN 95 WD40 REPEAT DOMAIN 95 LEPOC|Ensembl=ENSLOCG00000000705.1|UniProtKB=W5LXC6 W5LXC6 PTHR22747:SF13 NUCLEOPLASMIN NUCLEOPLASMIN-3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003915.1|UniProtKB=W5M8I3 W5M8I3 PTHR10194:SF26 RAS GTPASE-ACTIVATING PROTEINS DISABLED HOMOLOG 2-INTERACTING PROTEIN G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000017800.1|UniProtKB=W5NMP5 W5NMP5 PTHR11711:SF172 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 11 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005238.1|UniProtKB=W5MD51 W5MD51 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000009369.1|UniProtKB=W5MSS0 W5MSS0 PTHR10288:SF98 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013464.1|UniProtKB=W5N7J7 W5N7J7 CDKL2 PTHR24056:SF241 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008549.1|UniProtKB=W5MPV9 W5MPV9 PTHR11453:SF32 ANION EXCHANGE PROTEIN SODIUM-DRIVEN CHLORIDE BICARBONATE EXCHANGER secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009998.1|UniProtKB=W5MV18 W5MV18 PTHR15959:SF0 SYNTAXIN-18 SYNTAXIN-18 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;SNARE complex#GO:0031201;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006188.1|UniProtKB=W5MGG7 W5MGG7 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005415.1|UniProtKB=W5MDS4 W5MDS4 PTHR16024:SF7 XK-RELATED PROTEIN XK-RELATED PROTEIN 7 execution phase of apoptosis#GO:0097194;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;programmed cell death#GO:0012501;phospholipid transport#GO:0015914;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;biological regulation#GO:0065007;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001198.1|UniProtKB=W5LYZ0 W5LYZ0 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004457.1|UniProtKB=W5MAC5 W5MAC5 PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 LEPOC|Ensembl=ENSLOCG00000013903.1|UniProtKB=W5N938 W5N938 PTHR15360:SF1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 PDGF signaling pathway#P00047>PDGF receptor A#P01158;PDGF signaling pathway#P00047>PDGF receptor B#P01156 LEPOC|Ensembl=ENSLOCG00000004699.1|UniProtKB=W5MB70 W5MB70 PTHR11337:SF11 MUCIN/PORIMIN CD164 SIALOMUCIN-LIKE 2 PROTEIN cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004676.1|UniProtKB=W5MBB1 W5MBB1 PTHR45691:SF9 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 3 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 LEPOC|Ensembl=ENSLOCG00000005710.1|UniProtKB=W5MET1 W5MET1 PTHR12837:SF8 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;regulation of DNA repair#GO:0006282;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;purine ribonucleoside triphosphate metabolic process#GO:0009205;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014690.1|UniProtKB=W5NBS3 W5NBS3 PTHR14905:SF23 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000015280.1|UniProtKB=W5NDU3 W5NDU3 PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003596.1|UniProtKB=W5M7A4 W5M7A4 PTHR18952:SF25 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5B, MITOCHONDRIAL-RELATED carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000002551.1|UniProtKB=W5M3N8 W5M3N8 PTHR24115:SF454 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2C pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005235.1|UniProtKB=W5MD46 W5MD46 PTHR43289:SF13 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of chromosome segregation#GO:0051983;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;regulation of intracellular signal transduction#GO:1902531;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;chromosome segregation#GO:0007059;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;regulation of cell communication#GO:0010646;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;peptidyl-serine modification#GO:0018209;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011955.1|UniProtKB=W5N239 W5N239 C1QL1 PTHR22923:SF64 CEREBELLIN-RELATED C1Q-RELATED FACTOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012255.1|UniProtKB=W5N379 W5N379 PTHR11920:SF500 GUANYLYL CYCLASE GUANYLATE CYCLASE 2G adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000018140.1|UniProtKB=W5NNN2 W5NNN2 PTHR37557:SF4 115 KDA PROTEIN IN TYPE-1 RETROTRANSPOSABLE ELEMENT R1DM-LIKE PROTEIN-RELATED-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000017956.1|UniProtKB=W5NN50 W5NN50 PTHR46291:SF1 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4D LEPOC|Ensembl=ENSLOCG00000015424.1|UniProtKB=W5NEC7 W5NEC7 PTHR11905:SF32 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005894.1|UniProtKB=W5MFH3 W5MFH3 PTHR13183:SF0 AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28 AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1 protein binding#GO:0005515;binding#GO:0005488 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016397.1|UniProtKB=W5NHZ6 W5NHZ6 PTHR11036:SF23 SEMAPHORIN SEMAPHORIN-3A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 synapse#GO:0045202;extracellular region#GO:0005576;neuron projection#GO:0043005;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;extracellular space#GO:0005615;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Axon guidance mediated by semaphorins#P00007>Sema3A#P00337 LEPOC|Ensembl=ENSLOCG00000001111.1|UniProtKB=W5LYP1 W5LYP1 PTHR34762:SF1 SMALL VASOHIBIN-BINDING PROTEIN SMALL VASOHIBIN-BINDING PROTEIN cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;protein localization#GO:0008104;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein ubiquitination#GO:0031397;negative regulation of macromolecule metabolic process#GO:0010605;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;apical part of cell#GO:0045177 LEPOC|Ensembl=ENSLOCG00000013239.1|UniProtKB=W5N6P9 W5N6P9 PTHR22704:SF2 BMERB DOMAIN-CONTAINING PROTEIN 1-RELATED BMERB DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015028.1|UniProtKB=W5NCZ0 W5NCZ0 PTHR24064:SF470 SOLUTE CARRIER FAMILY 22 MEMBER SI:DKEY-166K12.1 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005038.1|UniProtKB=W5MCG0 W5MCG0 ZNF830 PTHR13278:SF0 ZINC FINGER PROTEIN 830 ZINC FINGER PROTEIN 830 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;DNA-templated DNA replication#GO:0006261;mitotic DNA replication checkpoint signaling#GO:0033314;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of mitotic cell cycle#GO:0045930;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA integrity checkpoint signaling#GO:0044774;cellular response to stress#GO:0033554;DNA replication#GO:0006260;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012676.1|UniProtKB=W5N4P0 W5N4P0 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;glycosyl compound metabolic process#GO:1901657;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147;Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146 LEPOC|Ensembl=ENSLOCG00000003689.1|UniProtKB=W5M7M3 W5M7M3 PTHR20648:SF13 ELONGIN-C ELONGIN-C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008939.1|UniProtKB=W5MR93 W5MR93 PTHR10336:SF31 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-4 lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000013261.1|UniProtKB=W5N6T9 W5N6T9 PTHR21292:SF13 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011098.1|UniProtKB=W5MZ21 W5MZ21 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000004769.1|UniProtKB=W5MBG9 W5MBG9 ALPP PTHR11596:SF92 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011086.1|UniProtKB=W5MZ07 W5MZ07 PTHR15427:SF5 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005790.1|UniProtKB=W5MF33 W5MF33 PTHR11776:SF7 ADENINE PHOSPHORIBOSYLTRANSFERASE PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763 transferase#PC00220;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 LEPOC|Ensembl=ENSLOCG00000010276.1|UniProtKB=W5MW35 W5MW35 PTHR12162:SF0 NIBRIN-RELATED NIBRIN damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;organic cyclic compound metabolic process#GO:1901360;signal transduction in response to DNA damage#GO:0042770;DNA duplex unwinding#GO:0032508;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;mitotic DNA damage checkpoint signaling#GO:0044773;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000005217.1|UniProtKB=W5MD25 W5MD25 PTHR48069:SF6 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;carboxylic acid metabolic process#GO:0019752;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 LEPOC|Ensembl=ENSLOCG00000014288.1|UniProtKB=W5NAD0 W5NAD0 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003192.1|UniProtKB=W5M5W0 W5M5W0 PTHR22739:SF20 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002196.1|UniProtKB=W5M2G0 W5M2G0 PTHR22589:SF50 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004935.1|UniProtKB=W5MC34 W5MC34 PTHR11390:SF21 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-ALPHA catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008941.1|UniProtKB=W5MR92 W5MR92 PTHR43243:SF28 INNER MEMBRANE TRANSPORTER YGJI-RELATED HIGH AFFINITY CATIONIC AMINO ACID TRANSPORTER 1 L-lysine transmembrane transporter activity#GO:0015189;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005559.1|UniProtKB=W5MEA8 W5MEA8 PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012947.1|UniProtKB=W5N5N4 W5N5N4 PTHR45941:SF4 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ST6 N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000004016.1|UniProtKB=W5M8U4 W5M8U4 PTHR10807:SF34 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 6 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000008585.1|UniProtKB=W5MPX7 W5MPX7 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003932.1|UniProtKB=W5M8J4 W5M8J4 PTHR24056:SF129 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 4 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001158.1|UniProtKB=W5LYU5 W5LYU5 PTHR31395:SF11 SHISA PROTEIN SHISA-LIKE-1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017100.1|UniProtKB=W5NKH1 W5NKH1 PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007348.1|UniProtKB=W5MKJ5 W5MKJ5 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005253.1|UniProtKB=W5MD73 W5MD73 PTHR24135:SF17 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;somatodendritic compartment#GO:0036477;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 LEPOC|Ensembl=ENSLOCG00000010687.1|UniProtKB=W5MXJ4 W5MXJ4 PTHR43416:SF5 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016114.1|UniProtKB=W5NGV1 W5NGV1 PTHR44468:SF2 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 8B ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000000771.1|UniProtKB=W5LXJ7 W5LXJ7 PTHR23351:SF25 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000003533.1|UniProtKB=W5M739 W5M739 PTHR11616:SF109 SODIUM/CHLORIDE DEPENDENT TRANSPORTER INACTIVE SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT3 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000006452.1|UniProtKB=W5MHD7 W5MHD7 PTHR11176:SF4 BOULE-RELATED DELETED IN AZOOSPERMIA-LIKE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of translational initiation#GO:0006446;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007236.1|UniProtKB=W5MK49 W5MK49 PTHR12439:SF40 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 LEPOC|Ensembl=ENSLOCG00000006415.1|UniProtKB=W5MH90 W5MH90 PTHR13193:SF0 CGI-140 PAT COMPLEX SUBUNIT ASTERIX protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006393.1|UniProtKB=W5MH67 W5MH67 PTHR10218:SF368 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN (G PROTEIN), ALPHA 11A (GQ CLASS)-RELATED GTPase activity#GO:0003924;molecular function activator activity#GO:0140677;binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;ribonucleoside triphosphate phosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Endothelin signaling pathway#P00019>Gq#P00586;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Alpha adrenergic receptor signaling pathway#P00002>G-Protein#P00077;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;PI3 kinase pathway#P00048>Galpha#P01199 LEPOC|Ensembl=ENSLOCG00000003342.1|UniProtKB=W5M6E9 W5M6E9 PTHR21595:SF3 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein depolymerization#GO:1901879;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011976.1|UniProtKB=W5N268 W5N268 PTHR13014:SF3 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML65 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016484.1|UniProtKB=W5NIA4 W5NIA4 PTHR35083:SF3 RGD1565685 PROTEIN SI:CH211-91P5.3 LEPOC|Ensembl=ENSLOCG00000007202.1|UniProtKB=W5MK08 W5MK08 PTHR44111:SF1 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006896.1|UniProtKB=W5MIX8 W5MIX8 NTF4 PTHR11589:SF8 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-4 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;response to growth factor#GO:0070848;regulation of signaling#GO:0023051;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;generation of neurons#GO:0048699 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;extracellular region#GO:0005576;cell junction#GO:0030054;dendrite#GO:0030425;extracellular space#GO:0005615;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000016238.1|UniProtKB=W5NHB6 W5NHB6 ZFC3H1 PTHR21563:SF3 ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;exosome (RNase complex)#GO:0000178;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014073.1|UniProtKB=W5N9N7 W5N9N7 PTHR12369:SF42 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012120.1|UniProtKB=W5N2Q6 W5N2Q6 CHIA PTHR11177:SF188 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002396.1|UniProtKB=W5M349 W5M349 PTHR24061:SF519 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002850.1|UniProtKB=W5M4P0 W5M4P0 PTHR45710:SF31 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010105.1|UniProtKB=W5MVF6 W5MVF6 PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 LEPOC|Ensembl=ENSLOCG00000007581.1|UniProtKB=W5MLE7 W5MLE7 PTHR24016:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010978.1|UniProtKB=W5MYK6 W5MYK6 PTHR17537:SF6 TRANSDUCER OF ERBB2 TOB PROTEIN TOB1 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003132.1|UniProtKB=W5M5M7 W5M5M7 PTHR14678:SF2 PROLINE-RICH PROTEIN 35-RELATED PROLINE-RICH PROTEIN 35 LEPOC|Ensembl=ENSLOCG00000003320.1|UniProtKB=W5M6B2 W5M6B2 PTHR46473:SF4 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 38 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;molecular function activator activity#GO:0140677;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;protein binding#GO:0005515;channel regulator activity#GO:0016247;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016369.1|UniProtKB=W5NHW0 W5NHW0 PTHR11119:SF86 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SI:DKEY-106N21.1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017496.1|UniProtKB=W5NLU2 W5NLU2 PTHR23033:SF2 BETA1,3-GALACTOSYLTRANSFERASE C1GALT1-SPECIFIC CHAPERONE 1 galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015303.1|UniProtKB=W5NDX2 W5NDX2 PTHR11972:SF203 NADPH OXIDASE NADPH OXIDASE 1 oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002116.1|UniProtKB=W5M254 W5M254 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;exosome (RNase complex)#GO:0000178;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000012266.1|UniProtKB=W5N383 W5N383 PTHR10454:SF206 CASPASE CASPASE-6 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Caspase6#P00596;FAS signaling pathway#P00020>Pro-Caspase6#P00607 LEPOC|Ensembl=ENSLOCG00000014651.1|UniProtKB=W5NBM8 W5NBM8 PTHR22576:SF38 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1-LIKE cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014975.1|UniProtKB=W5NCS7 W5NCS7 PTHR21136:SF179 SNARE PROTEINS VESICLE ASSOCIATED MEMBRANE PROTEIN 7-RELATED molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;organelle fusion#GO:0048284;secretion by cell#GO:0032940 SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000012809.1|UniProtKB=W5N563 W5N563 PTHR45836:SF3 SLIT HOMOLOG SLIT HOMOLOG 1 PROTEIN heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 LEPOC|Ensembl=ENSLOCG00000010746.1|UniProtKB=W5MXR4 W5MXR4 PTHR11254:SF79 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of dendrite development#GO:0050773;negative regulation of biological process#GO:0048519;regulation of sodium ion transport#GO:0002028;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;regulation of metal ion transport#GO:0010959;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of monoatomic cation transmembrane transport#GO:1904062;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;organic substance catabolic process#GO:1901575;regulation of transporter activity#GO:0032409;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of transport#GO:0051051;regulation of plasma membrane bounded cell projection organization#GO:0120035;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron projection development#GO:0010975;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012599.1|UniProtKB=W5N4G7 W5N4G7 PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;TORC2 signaling#GO:0038203;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000000589.1|UniProtKB=W5LWZ5 W5LWZ5 PTHR10603:SF6 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;RNA localization#GO:0006403;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;RNA transport#GO:0050658;regulation of neuronal synaptic plasticity#GO:0048168;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of multicellular organismal process#GO:0051239;establishment of RNA localization#GO:0051236;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;regulation of trans-synaptic signaling#GO:0099177;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule localization#GO:0033036;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;regulation of amide metabolic process#GO:0034248;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;nucleic acid transport#GO:0050657;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cell communication#GO:0010646;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;regulation of cellular catabolic process#GO:0031329;mRNA transport#GO:0051028;positive regulation of developmental process#GO:0051094;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cell projection#GO:0042995 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000009198.1|UniProtKB=W5MS62 W5MS62 PTHR20933:SF3 F-BOX ONLY PROTEIN 33 F-BOX ONLY PROTEIN 33 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of protein modification process#GO:0031399;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of protein metabolic process#GO:0051246;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;biological regulation#GO:0065007;positive regulation of protein modification process#GO:0031401;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 LEPOC|Ensembl=ENSLOCG00000010845.1|UniProtKB=W5MY29 W5MY29 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012192.1|UniProtKB=W5N2Y7 W5N2Y7 PTHR12975:SF6 TRANSPORT PROTEIN TRAPP TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005178.1|UniProtKB=W5MCY1 W5MCY1 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009517.1|UniProtKB=W5MTC6 W5MTC6 PTHR44981:SF3 PERICENTRIN-LIKE PROTEIN, ISOFORM F PERICENTRIN LEPOC|Ensembl=ENSLOCG00000006126.1|UniProtKB=W5MG93 W5MG93 PTHR10489:SF936 CELL ADHESION MOLECULE G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009752.1|UniProtKB=W5MU57 W5MU57 PTHR28544:SF1 PROTEIN FAM45A-RELATED DENN DOMAIN-CONTAINING PROTEIN 10-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007325.1|UniProtKB=W5MKG3 W5MKG3 PTHR22950:SF190 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID UNIPORTER 4 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;organic acid transmembrane transport#GO:1903825 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005445.1|UniProtKB=W5MDV4 W5MDV4 C16orf87 PTHR31101:SF2 UPF0547 PROTEIN C16ORF87 C16ORF87 HOMOLOG LEPOC|Ensembl=ENSLOCG00000001022.1|UniProtKB=W5LYD9 W5LYD9 NAALADL2 PTHR10404:SF32 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE INACTIVE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011239.1|UniProtKB=W5MZK4 W5MZK4 AK3 PTHR23359:SF68 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000014979.1|UniProtKB=W5NCT3 W5NCT3 PTHR11259:SF1 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000007732.1|UniProtKB=W5MLZ9 W5MLZ9 PTHR11036:SF11 SEMAPHORIN SEMAPHORIN-6C molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;axon guidance#GO:0007411;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell communication#GO:0007154;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012373.1|UniProtKB=W5N3M5 W5N3M5 PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017691.1|UniProtKB=W5NMD7 W5NMD7 PTHR40472:SF9 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 4 LEPOC|Ensembl=ENSLOCG00000000257.1|UniProtKB=W5LVX5 W5LVX5 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED SI:CH211-113E8.5 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001108.1|UniProtKB=W5LYN7 W5LYN7 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA processing factor#PC00147 p53 pathway#P00059>PAG608#G04690 LEPOC|Ensembl=ENSLOCG00000008857.1|UniProtKB=W5MQW6 W5MQW6 PTHR23285:SF2 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3A RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013342.1|UniProtKB=W5N743 W5N743 PTHR13373:SF21 FROUNT PROTEIN-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP85 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;RNA transport#GO:0050658;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule localization#GO:0033036;positive regulation of RNA biosynthetic process#GO:1902680;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;protein localization to organelle#GO:0033365;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;positive regulation of RNA metabolic process#GO:0051254;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016150.1|UniProtKB=W5NGY9 W5NGY9 PTHR10173:SF56 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B3 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003876.1|UniProtKB=W5M8B0 W5M8B0 PTHR14015:SF1 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013567.1|UniProtKB=W5N7W7 W5N7W7 IGFBP4 PTHR11551:SF7 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 4 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003440.1|UniProtKB=W5M6R1 W5M6R1 PTHR22696:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF26 E3 UBIQUITIN-PROTEIN LIGASE RNF26 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017952.1|UniProtKB=W5NN46 W5NN46 PTHR48043:SF52 EG:EG0003.4 PROTEIN-RELATED UDP GLUCURONOSYLTRANSFERASE 5 FAMILY POLYPEPTIDE B1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 LEPOC|Ensembl=ENSLOCG00000002177.1|UniProtKB=W5M2E8 W5M2E8 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000008983.1|UniProtKB=W5MRE2 W5MRE2 PTHR45889:SF1 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 2 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 LEPOC|Ensembl=ENSLOCG00000009287.1|UniProtKB=W5MSG5 W5MSG5 PTHR36961:SF1 LEUKEMIA-ASSOCIATED PROTEIN 7 LEUKEMIA-ASSOCIATED PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000000010.1|UniProtKB=W5LV54 W5LV54 PTHR46066:SF2 CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER CHITINASE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000004839.1|UniProtKB=W5MBQ5 W5MBQ5 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017105.1|UniProtKB=W5NKH9 W5NKH9 PTHR28547:SF1 PROTEIN MMS22-LIKE PROTEIN MMS22-LIKE DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 LEPOC|Ensembl=ENSLOCG00000002044.1|UniProtKB=W5M1W7 W5M1W7 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000016352.1|UniProtKB=W5NHT4 W5NHT4 PTHR35760:SF1 SI:CH211-22I13.2 SI:CH211-22I13.2 LEPOC|Ensembl=ENSLOCG00000004154.1|UniProtKB=W5M9B0 W5M9B0 PTHR12247:SF130 POLYCOMB GROUP PROTEIN SAM DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017646.1|UniProtKB=W5NM92 W5NM92 PTHR26450:SF87 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014200.1|UniProtKB=W5NA35 W5NA35 PTHR11216:SF62 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;plasma membrane bounded cell projection organization#GO:0120036;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization#GO:0008104;organelle assembly#GO:0070925;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009604.1|UniProtKB=W5MTM0 W5MTM0 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012961.1|UniProtKB=W5N5Q2 W5N5Q2 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003141.1|UniProtKB=W5M5U0 W5M5U0 PTHR34399:SF3 AVIDIN-RELATED AVID PROTEIN-RELATED small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 LEPOC|Ensembl=ENSLOCG00000000167.1|UniProtKB=W5LVM9 W5LVM9 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000727.1|UniProtKB=W5LXE8 W5LXE8 PTHR13809:SF8 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-7 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 LEPOC|Ensembl=ENSLOCG00000007729.1|UniProtKB=W5MLX5 W5MLX5 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015226.1|UniProtKB=W5NDM8 W5NDM8 PTHR19964:SF41 MULTIPLE PDZ DOMAIN PROTEIN LIGAND OF NUMB PROTEIN X 2-LIKE aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011606.1|UniProtKB=W5N0V8 W5N0V8 PTHR45624:SF3 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 47 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018121.1|UniProtKB=W5NNL3 W5NNL3 THNSL1 PTHR43515:SF1 THREONINE SYNTHASE-LIKE 1 THREONINE SYNTHASE-LIKE 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Threonine biosynthesis#P02781>Threonine synthase#P03190 LEPOC|Ensembl=ENSLOCG00000000197.1|UniProtKB=W5LVR3 W5LVR3 PTHR12259:SF2 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009685.1|UniProtKB=W5MTW6 W5MTW6 PTHR33198:SF20 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012372.1|UniProtKB=W5N3M1 W5N3M1 RAC3 PTHR24072:SF325 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;Rac protein signal transduction#GO:0016601;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;intracellular signaling cassette#GO:0141124;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;establishment or maintenance of cell polarity#GO:0007163;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;regulation of leukocyte migration#GO:0002685;neuron differentiation#GO:0030182;regulation of actin cytoskeleton organization#GO:0032956;regulation of immune system process#GO:0002682;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell chemotaxis#GO:0060326;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;motor neuron axon guidance#GO:0008045;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;generation of neurons#GO:0048699;cell migration#GO:0016477 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;p38 MAPK pathway#P05918>Rac#P06021;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;VEGF signaling pathway#P00056>Rac#P01421;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;B cell activation#P00010>Rac#P00385;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 LEPOC|Ensembl=ENSLOCG00000005753.1|UniProtKB=W5MEY8 W5MEY8 PTHR12449:SF19 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4-LIKE LEPOC|Ensembl=ENSLOCG00000014913.1|UniProtKB=W5NCK5 W5NCK5 PTHR13809:SF19 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-8 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 LEPOC|Ensembl=ENSLOCG00000017254.1|UniProtKB=W5NL33 W5NL33 PTHR11984:SF105 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000005256.1|UniProtKB=W5MD71 W5MD71 PTHR14002:SF24 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009072.1|UniProtKB=W5MRQ5 W5MRQ5 PTHR24203:SF14 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000002495.1|UniProtKB=W5M3H9 W5M3H9 PTHR16243:SF2 BTG3-ASSOCIATED NUCLEAR PROTEIN BANP PROTEIN BANP cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;protein localization to nucleus#GO:0034504;regulation of protein catabolic process#GO:0042176;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;protein localization#GO:0008104;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;cellular macromolecule localization#GO:0070727;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;protein localization to organelle#GO:0033365;regulation of metabolic process#GO:0019222 LEPOC|Ensembl=ENSLOCG00000011451.1|UniProtKB=W5N0B4 W5N0B4 PTHR46135:SF5 NME/NM23 FAMILY MEMBER 8 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000003356.1|UniProtKB=W5M6F2 W5M6F2 RPL27A PTHR11721:SF3 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008317.1|UniProtKB=W5MP00 W5MP00 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 69 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005995.1|UniProtKB=W5MFT6 W5MFT6 PTHR31840:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 LEPOC|Ensembl=ENSLOCG00000002120.1|UniProtKB=W5M274 W5M274 PTHR45817:SF2 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 3 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006277.1|UniProtKB=W5MGS4 W5MGS4 PTHR12081:SF42 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000017525.1|UniProtKB=W5NLX1 W5NLX1 PTHR24232:SF0 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>mPAR-3#P00452 LEPOC|Ensembl=ENSLOCG00000003268.1|UniProtKB=W5M648 W5M648 PTHR23310:SF54 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013218.1|UniProtKB=W5N6M4 W5N6M4 PTHR23048:SF50 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 4-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002708.1|UniProtKB=W5M493 W5M493 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG cell division#GO:0051301;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of mitotic nuclear division#GO:0045840;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005379.1|UniProtKB=W5MDM3 W5MDM3 PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005746.1|UniProtKB=W5MEY1 W5MEY1 PTHR22805:SF2 WDR41-RELATED WD REPEAT-CONTAINING PROTEIN 41 LEPOC|Ensembl=ENSLOCG00000008675.1|UniProtKB=W5MQ88 W5MQ88 PTHR28626:SF3 SRR1-LIKE PROTEIN SRR1-LIKE PROTEIN cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013545.1|UniProtKB=W5N7T9 W5N7T9 PTHR31882:SF6 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 2 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;activation of immune response#GO:0002253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;regulation of signal transduction#GO:0009966;response to molecule of bacterial origin#GO:0002237;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;response to lipid#GO:0033993;pattern recognition receptor signaling pathway#GO:0002221;cellular response to lipid#GO:0071396;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;regulation of immune system process#GO:0002682;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;intracellular receptor signaling pathway#GO:0030522;regulation of gene expression#GO:0010468;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cellular response to molecule of bacterial origin#GO:0071219;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 LEPOC|Ensembl=ENSLOCG00000013516.1|UniProtKB=W5N7S0 W5N7S0 PTHR28678:SF1 CODANIN-1 CODANIN-1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016564.1|UniProtKB=W5NIK0 W5NIK0 PTHR24006:SF796 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBL CARBOXYL-TERMINAL HYDROLASE 18-RELATED cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011566.1|UniProtKB=W5N0Q4 W5N0Q4 PTHR46753:SF3 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 PDZ DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011370.1|UniProtKB=W5N025 W5N025 PTHR42757:SF34 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED MAM DOMAIN CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR 2 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008209.1|UniProtKB=W5MNK8 W5MNK8 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007891.1|UniProtKB=W5MMH4 W5MMH4 PTHR13407:SF1 RNF121 PROTEIN E3 UBIQUITIN LIGASE RNF121 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011700.1|UniProtKB=W5N173 W5N173 PTHR10778:SF10 SOLUTE CARRIER FAMILY 35 MEMBER B SOLUTE CARRIER FAMILY 35 MEMBER B1 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;UDP-galactose transmembrane transporter activity#GO:0005459;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017948.1|UniProtKB=W5NN42 W5NN42 PTHR24369:SF178 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009955.1|UniProtKB=W5MUW4 W5MUW4 PTHR31134:SF1 TRANSMEMBRANE PROTEIN 128 TRANSMEMBRANE PROTEIN 128 LEPOC|Ensembl=ENSLOCG00000012897.1|UniProtKB=W5N5I3 W5N5I3 PTHR10169:SF61 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-ALPHA cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 LEPOC|Ensembl=ENSLOCG00000011476.1|UniProtKB=W5N0F2 W5N0F2 PTHR15288:SF2 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2D membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004573.1|UniProtKB=W5MAR0 W5MAR0 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006782.1|UniProtKB=W5MII1 W5MII1 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013694.1|UniProtKB=W5N8C4 W5N8C4 PTHR12902:SF9 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 cell leading edge#GO:0031252;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003554.1|UniProtKB=W5M748 W5M748 PTHR47011:SF1 CD226 ANTIGEN CD226 ANTIGEN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;gene expression#GO:0010467;positive regulation of immune system process#GO:0002684;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;cytokine production#GO:0001816;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;biological regulation#GO:0065007;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune system process#GO:0002682;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016697.1|UniProtKB=W5NJ23 W5NJ23 PTHR11675:SF50 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 8-RELATED transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014786.1|UniProtKB=W5NC52 W5NC52 PTHR45620:SF5 PDF RECEPTOR-LIKE PROTEIN-RELATED GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015610.1|UniProtKB=W5NF08 W5NF08 PTHR43139:SF5 SI:DKEY-122A22.2 MESODERM-SPECIFIC TRANSCRIPT PROTEIN serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008805.1|UniProtKB=W5MQR1 W5MQR1 PTHR10073:SF54 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL PMS1 PROTEIN HOMOLOG 1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001212.1|UniProtKB=W5LZ09 W5LZ09 PTHR35671:SF1 PROTEIN TOPAZ1 PROTEIN TOPAZ1 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;cell division#GO:0051301;gamete generation#GO:0007276;reproduction#GO:0000003;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multicellular organismal reproductive process#GO:0048609 LEPOC|Ensembl=ENSLOCG00000011619.1|UniProtKB=W5N0X0 W5N0X0 PTHR14383:SF2 SWAP-70 RECOMBINASE DIFFERENTIALLY EXPRESSED IN FDCP 6 HOMOLOG cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016895.1|UniProtKB=W5NJS9 W5NJS9 PTHR24020:SF17 COLLAGEN ALPHA COLLAGEN ALPHA-1(XII) CHAIN cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;cell differentiation#GO:0030154;endoderm formation#GO:0001706;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;endoderm development#GO:0007492;gastrulation#GO:0007369 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000014111.1|UniProtKB=W5N9W6 W5N9W6 PTHR45628:SF11 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1D calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 LEPOC|Ensembl=ENSLOCG00000002078.1|UniProtKB=W5M209 W5M209 PTHR44196:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B cellular anatomical entity#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002744.1|UniProtKB=W5M4C4 W5M4C4 PTHR11950:SF43 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;ossification#GO:0001503;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Runt transcription factor#PC00254;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000017570.1|UniProtKB=W5NM16 W5NM16 PTHR31974:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000009703.1|UniProtKB=W5MTY8 W5MTY8 MFSD3 PTHR12778:SF10 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 3 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004924.1|UniProtKB=W5MC12 W5MC12 PTHR24027:SF319 CADHERIN-23 CADHERIN-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 cadherin#PC00057 CCKR signaling map#P06959>E-cadherin#G06981;Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Cadherin signaling pathway#P00012>Cadherin#P00471;CCKR signaling map#P06959>E-cadherin#P07171;CCKR signaling map#P06959>E-cadherin#G07274;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118 LEPOC|Ensembl=ENSLOCG00000001492.1|UniProtKB=W5LZZ6 W5LZZ6 PTHR46615:SF1 ARYLSULFATASE K ARYLSULFATASE K hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000013362.1|UniProtKB=W5N767 W5N767 PTHR13140:SF313 MYOSIN UNCONVENTIONAL MYOSIN-VC microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000014057.1|UniProtKB=W5N9M1 W5N9M1 PTHR11915:SF434 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 muscle structure development#GO:0061061;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cortical actin cytoskeleton#GO:0030864;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cell projection#GO:0042995;cytoskeleton#GO:0005856;myofibril#GO:0030016;plasma membrane#GO:0005886;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000015925.1|UniProtKB=W5NG55 W5NG55 PTHR15653:SF2 STRIATIN STRIATIN phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;protein phosphatase binding#GO:0019903;binding#GO:0005488 dendrite#GO:0030425;dendritic tree#GO:0097447;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000000403.1|UniProtKB=W5LWE0 W5LWE0 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014980.1|UniProtKB=W5NCT2 W5NCT2 PTHR11937:SF195 ACTIN BETA-CENTRACTIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 LEPOC|Ensembl=ENSLOCG00000017572.1|UniProtKB=W5NM18 W5NM18 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014031.1|UniProtKB=W5N9I6 W5N9I6 PTHR23019:SF2 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004777.1|UniProtKB=W5MBH1 W5MBH1 PTHR46289:SF2 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED THAP DOMAIN CONTAINING 12 LEPOC|Ensembl=ENSLOCG00000004362.1|UniProtKB=W5MA25 W5MA25 PTHR11533:SF156 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015756.1|UniProtKB=W5NFI8 W5NFI8 PTHR44523:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 13 TETRATRICOPEPTIDE REPEAT PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000014486.1|UniProtKB=W5NB20 W5NB20 PTHR13568:SF6 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185A LEPOC|Ensembl=ENSLOCG00000008708.1|UniProtKB=W5MQE0 W5MQE0 PTHR44819:SF1 V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell activation#GO:0050866;negative regulation of cell adhesion#GO:0007162;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;regulation of cellular process#GO:0050794;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013364.1|UniProtKB=W5N762 W5N762 PTHR34930:SF4 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000003998.1|UniProtKB=W5M8S5 W5M8S5 PTHR24349:SF114 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p38 MAPK pathway#P05918>MNK1#P06018;Oxidative stress response#P00046>MNK1/2#P01137;Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149 LEPOC|Ensembl=ENSLOCG00000002113.1|UniProtKB=W5M240 W5M240 PTHR24366:SF154 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS NYCTALOPIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007431.1|UniProtKB=W5MKW1 W5MKW1 PTHR23115:SF36 TRANSLATION FACTOR G1 TO S PHASE TRANSITION 2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012864.1|UniProtKB=W5N5D6 W5N5D6 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008740.1|UniProtKB=W5MQI5 W5MQI5 PTHR14593:SF5 WD REPEAT-CONTAINING PROTEIN 11 WD REPEAT-CONTAINING PROTEIN 11 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017248.1|UniProtKB=W5NL25 W5NL25 PTHR11742:SF31 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IA hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014652.1|UniProtKB=W5NBM6 W5NBM6 PTHR24044:SF507 NOTCH LIGAND FAMILY MEMBER NOTCH HOMOLOG 2 N-TERMINAL-LIKE PROTEIN B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014678.1|UniProtKB=W5NBQ7 W5NBQ7 NMB PTHR16866:SF3 GASTRIN-RELEASING PEPTIDE NEUROMEDIN-B neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of hormone levels#GO:0010817;positive regulation of hormone secretion#GO:0046887;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;positive regulation of cell communication#GO:0010647;regulation of hormone secretion#GO:0046883;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000004484.1|UniProtKB=W5MAF3 W5MAF3 UNG PTHR11264:SF0 URACIL-DNA GLYCOSYLASE URACIL-DNA GLYCOSYLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000008328.1|UniProtKB=W5MP07 W5MP07 PTHR24208:SF115 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009358.1|UniProtKB=W5MSS9 W5MSS9 PTHR45819:SF2 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;ribonucleoside triphosphate phosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000014266.1|UniProtKB=W5NAA7 W5NAA7 PTHR11787:SF4 RAB GDP-DISSOCIATION INHIBITOR CHM, RAB ESCORT PROTEIN 1 localization#GO:0051179;establishment of localization#GO:0051234;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;transport#GO:0006810;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010035.1|UniProtKB=W5MV75 W5MV75 PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000018341.1|UniProtKB=W5NP83 W5NP83 KCNS2 PTHR11537:SF60 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000011726.1|UniProtKB=W5N1A8 W5N1A8 PTHR12461:SF99 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013791.1|UniProtKB=W5N8Q4 W5N8Q4 PTHR13817:SF95 TITIN PROTOGENIN structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005311.1|UniProtKB=W5MDD9 W5MDD9 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008650.1|UniProtKB=W5MQ58 W5MQ58 PTHR45691:SF18 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004329.1|UniProtKB=W5M9X6 W5M9X6 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016780.1|UniProtKB=W5NJD3 W5NJD3 PTHR43851:SF1 FAMILY NOT NAMED ATYPICAL KINASE COQ8A, MITOCHONDRIAL cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 LEPOC|Ensembl=ENSLOCG00000016757.1|UniProtKB=W5NJA9 W5NJA9 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 cellular aromatic compound metabolic process#GO:0006725;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic DNA replication#GO:1902969;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA strand elongation involved in DNA replication#GO:0006271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cell cycle DNA replication#GO:0044786 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000000865.1|UniProtKB=W5LXV7 W5LXV7 PTHR12178:SF3 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 3 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of protein metabolic process#GO:0051246;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015286.1|UniProtKB=W5NDU8 W5NDU8 PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001670.1|UniProtKB=W5M0L8 W5M0L8 PTHR23088:SF27 NITRILASE-RELATED DEAMINATED GLUTATHIONE AMIDASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004620.1|UniProtKB=W5MAX7 W5MAX7 PTHR21119:SF7 C2 DOMAIN-CONTAINING PROTEIN C2 DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000938.1|UniProtKB=W5LY41 W5LY41 EIF3F PTHR10540:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000009811.1|UniProtKB=W5MUD1 W5MUD1 PTHR15079:SF3 MYD88 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 scaffold/adaptor protein#PC00226 Toll pathway-drosophila#P06217>MyD88#P06346;Toll receptor signaling pathway#P00054>MyD88#P01377 LEPOC|Ensembl=ENSLOCG00000004515.1|UniProtKB=W5MAJ1 W5MAJ1 PTHR10489:SF671 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 3 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000004070.1|UniProtKB=W5M8Z8 W5M8Z8 PTHR31395:SF0 SHISA PROTEIN SHISA-2 HOMOLOG scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018218.1|UniProtKB=W5NNW0 W5NNW0 PTHR24235:SF20 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 2 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005630.1|UniProtKB=W5MEJ5 W5MEJ5 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX31-RELATED cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000005812.1|UniProtKB=W5MF62 W5MF62 PTHR15963:SF1 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED CYTOHESIN-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000008199.1|UniProtKB=W5MNJ4 W5MNJ4 PTHR12022:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017113.1|UniProtKB=W5NKI7 W5NKI7 PTHR32261:SF8 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 5 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000006431.1|UniProtKB=W5MHA7 W5MHA7 PTHR24067:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013160.1|UniProtKB=W5N6F3 W5N6F3 PTHR10605:SF68 HEPARAN SULFATE SULFOTRANSFERASE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007037.1|UniProtKB=W5MJG0 W5MJG0 PTHR20766:SF2 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 LEPOC|Ensembl=ENSLOCG00000014117.1|UniProtKB=W5N9T2 W5N9T2 PTHR24070:SF252 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN FAMILY MEMBER 12 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000004258.1|UniProtKB=W5M9N4 W5M9N4 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002285.1|UniProtKB=W5M2R4 W5M2R4 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005691.1|UniProtKB=W5MER2 W5MER2 PTHR10219:SF20 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015261.1|UniProtKB=W5NDS1 W5NDS1 PTHR45636:SF6 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013232.1|UniProtKB=W5N6Q0 W5N6Q0 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010764.1|UniProtKB=W5MXT3 W5MXT3 PTHR23103:SF7 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-BETA PRECURSOR PROTEIN signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;central nervous system development#GO:0007417;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell surface#GO:0009986;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 protease inhibitor#PC00191 Blood coagulation#P00011>PN2#P00429;Alzheimer disease-amyloid secretase pathway#P00003>C99#P00106;Alzheimer disease-amyloid secretase pathway#P00003>p3#P00086;Alzheimer disease-amyloid secretase pathway#P00003>Abeta#P00096;Alzheimer disease-amyloid secretase pathway#P00003>C83#P00100;Alzheimer disease-amyloid secretase pathway#P00003>AICD#P00080;Alzheimer disease-amyloid secretase pathway#P00003>APP#P00085;Alzheimer disease-presenilin pathway#P00004>APPbeta#P00151;Alzheimer disease-amyloid secretase pathway#P00003>APPalpha#P00097;Alzheimer disease-presenilin pathway#P00004>APP#P00127;Alzheimer disease-amyloid secretase pathway#P00003>APPbeta#P00104;Alzheimer disease-presenilin pathway#P00004>C99#P00111;Alzheimer disease-presenilin pathway#P00004>AICD#P00166;Alzheimer disease-presenilin pathway#P00004>Abeta#P00136 LEPOC|Ensembl=ENSLOCG00000000254.1|UniProtKB=W5LVX2 W5LVX2 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016430.1|UniProtKB=W5NI51 W5NI51 THADA PTHR14387:SF7 THADA/DEATH RECEPTOR INTERACTING PROTEIN THYROID ADENOMA-ASSOCIATED PROTEIN cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013237.1|UniProtKB=W5N6P3 W5N6P3 PTHR15907:SF107 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000004905.1|UniProtKB=W5MBY9 W5MBY9 GSC2 PTHR46643:SF1 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002275.1|UniProtKB=W5M2R8 W5M2R8 GADL1 PTHR45677:SF1 GLUTAMATE DECARBOXYLASE-RELATED ACIDIC AMINO ACID DECARBOXYLASE GADL1 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000014115.1|UniProtKB=W5N9T1 W5N9T1 PTHR22802:SF461 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 1 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001916.1|UniProtKB=W5M1G3 W5M1G3 PTHR14618:SF5 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005834.1|UniProtKB=W5MF85 W5MF85 PTHR13439:SF5 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane assembly#GO:0071709;regulation of biological quality#GO:0065008;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005204.1|UniProtKB=W5MD04 W5MD04 PTHR21184:SF3 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151B extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000007552.1|UniProtKB=W5ML97 W5ML97 PTHR12800:SF3 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein stabilization#GO:0050821;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;biological regulation#GO:0065007;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014716.1|UniProtKB=W5NBY0 W5NBY0 PTHR24416:SF627 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018167.1|UniProtKB=W5NNQ9 W5NNQ9 PTHR11786:SF3 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000011245.1|UniProtKB=W5MZL6 W5MZL6 PTHR23115:SF191 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000389.1|UniProtKB=W5LWB7 W5LWB7 ARCN1 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000012125.1|UniProtKB=W5N2R2 W5N2R2 PTHR43684:SF1 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 LEPOC|Ensembl=ENSLOCG00000003304.1|UniProtKB=W5M6A4 W5M6A4 PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein export from nucleus#GO:0006611;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;nuclear transport#GO:0051169 LEPOC|Ensembl=ENSLOCG00000003927.1|UniProtKB=W5M8I4 W5M8I4 PTHR12919:SF20 30S RIBOSOMAL PROTEIN S16 SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015523.1|UniProtKB=W5NEP7 W5NEP7 PTHR23064:SF78 TROPONIN CARDIAC TROPONIN C-RELATED cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003031.1|UniProtKB=W5M5C2 W5M5C2 PTHR44170:SF3 PROTEIN SIDEKICK BROTHER OF CDO neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;neuron projection development#GO:0031175;cellular component organization or biogenesis#GO:0071840;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;axon#GO:0030424 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001615.1|UniProtKB=W5M0F1 W5M0F1 PTHR23238:SF25 RNA BINDING PROTEIN TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002162.1|UniProtKB=W5M2A7 W5M2A7 PTHR10666:SF438 UBIQUITIN POLYUBIQUITIN-C structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytosolic ribosome#GO:0022626;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840 LEPOC|Ensembl=ENSLOCG00000000118.1|UniProtKB=W5LVH5 W5LVH5 PTHR26451:SF896 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000980.1|UniProtKB=W5LY93 W5LY93 PTHR11993:SF10 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001638.1|UniProtKB=W5M0K0 W5M0K0 PTHR13759:SF8 TWINFILIN TWINFILIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785;actin filament binding#GO:0051015 cellular localization#GO:0051641;negative regulation of protein depolymerization#GO:1901880;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of protein-containing complex disassembly#GO:0043244;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of protein depolymerization#GO:1901879;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;regulation of cell projection organization#GO:0031344;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein polymerization#GO:0032272;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of plasma membrane bounded cell projection assembly#GO:0120032;macromolecule localization#GO:0033036;regulation of protein-containing complex assembly#GO:0043254;cellular component disassembly#GO:0022411;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;regulation of actin filament depolymerization#GO:0030834;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;regulation of cell projection assembly#GO:0060491;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012931.1|UniProtKB=W5N5L5 W5N5L5 PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017328.1|UniProtKB=W5NLC4 W5NLC4 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000013667.1|UniProtKB=W5N8A9 W5N8A9 PTHR46357:SF1 TRANSCRIPTIONAL REGULATOR ATRX TRANSCRIPTIONAL REGULATOR ATRX nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;protein-containing complex organization#GO:0043933;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;chromatin organization#GO:0006325;replication fork processing#GO:0031297;DNA replication#GO:0006260;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome, centromeric region#GO:0000775;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003007.1|UniProtKB=W5M598 W5M598 PTHR46769:SF2 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN-L ISOFORM 2 PRECURSOR-RELATED LEPOC|Ensembl=ENSLOCG00000008870.1|UniProtKB=W5MQY8 W5MQY8 SPATC1L PTHR22192:SF17 SPERIOLIN SPERIOLIN-LIKE PROTEIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000014740.1|UniProtKB=W5NC05 W5NC05 PTHR19981:SF34 TALIN TALIN-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell adhesion#GO:0007155;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004693.1|UniProtKB=W5MB65 W5MB65 PTHR10551:SF39 FASCIN FASCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament bundle assembly#GO:0051017;cell motility#GO:0048870;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012420.1|UniProtKB=W5N3T7 W5N3T7 PLEKHH3 PTHR46049:SF5 AGAP003327-PA PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000001031.1|UniProtKB=W5LYG1 W5LYG1 PTHR11216:SF29 EH DOMAIN INTERSECTIN-2 endosomal transport#GO:0016197;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;localization#GO:0051179;synaptic vesicle recycling#GO:0036465;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;vesicle#GO:0031982;presynaptic membrane#GO:0042734;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012079.1|UniProtKB=W5N2K0 W5N2K0 PTHR21493:SF245 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1A cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009698.1|UniProtKB=W5MTY2 W5MTY2 PTHR24339:SF25 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000015391.1|UniProtKB=W5NE87 W5NE87 PTHR11905:SF136 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>MDC9#P00090 LEPOC|Ensembl=ENSLOCG00000004407.1|UniProtKB=W5MA62 W5MA62 PTHR24253:SF50 TRANSMEMBRANE PROTEASE SERINE SUPPRESSOR OF TUMORIGENICITY 14 PROTEIN serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010638.1|UniProtKB=W5MXE0 W5MXE0 PTHR13297:SF5 TBC1 DOMAIN FAMILY MEMBER 23-RELATED TBC1 DOMAIN FAMILY MEMBER 23 endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008129.1|UniProtKB=W5MNB8 W5MNB8 PTHR10110:SF62 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008793.1|UniProtKB=W5MQQ2 W5MQQ2 PTHR12296:SF18 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4B regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015041.1|UniProtKB=W5ND03 W5ND03 PTHR12137:SF32 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 11 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002948.1|UniProtKB=W5M523 W5M523 TSPOAP1 PTHR14234:SF20 RIM BINDING PROTEIN-RELATED PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;neuromuscular synaptic transmission#GO:0007274;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000036.1|UniProtKB=W5LV83 W5LV83 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015533.1|UniProtKB=W5NEQ7 W5NEQ7 PTHR16155:SF18 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002003.1|UniProtKB=W5M1Q3 W5M1Q3 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;pICln-Sm protein complex#GO:0034715;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000001278.1|UniProtKB=W5LZA4 W5LZA4 PTHR46164:SF1 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to unfolded protein#GO:0006986;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000000468.1|UniProtKB=W5LWK5 W5LWK5 PTHR21266:SF32 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012784.1|UniProtKB=W5N531 W5N531 PTHR10676:SF339 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 6 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341 catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000002444.1|UniProtKB=W5M3A8 W5M3A8 PTHR24392:SF56 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 510 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008256.1|UniProtKB=W5MNR7 W5MNR7 PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;response to oxygen levels#GO:0070482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;cyclic-nucleotide-mediated signaling#GO:0019935;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 LEPOC|Ensembl=ENSLOCG00000004821.1|UniProtKB=W5MBN5 W5MBN5 PTHR46485:SF1 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002366.1|UniProtKB=W5M316 W5M316 PTHR22791:SF30 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 223-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006237.1|UniProtKB=W5MGP2 W5MGP2 PTHR31844:SF1 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED PROTEIN FAM168A positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of DNA repair#GO:0045739;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;regulation of response to stress#GO:0080134;positive regulation of macromolecule metabolic process#GO:0010604;regulation of DNA repair#GO:0006282;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016917.1|UniProtKB=W5NJV5 W5NJV5 PTHR22775:SF44 SORTING NEXIN SORTING NEXIN-14 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016675.1|UniProtKB=W5NIZ2 W5NIZ2 PTHR23123:SF15 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 7A histone modifying activity#GO:0140993;molecular adaptor activity#GO:0060090;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000015186.1|UniProtKB=W5NDH7 W5NDH7 PTHR10414:SF32 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016507.1|UniProtKB=W5NID1 W5NID1 PTHR12756:SF23 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 3 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001138.1|UniProtKB=W5LYU7 W5LYU7 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015694.1|UniProtKB=W5NFB4 W5NFB4 PTHR13096:SF8 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 1 LEPOC|Ensembl=ENSLOCG00000016828.1|UniProtKB=W5NJJ4 W5NJJ4 PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-presenilin pathway#P00004>TACE#P00147 LEPOC|Ensembl=ENSLOCG00000011719.1|UniProtKB=W5N194 W5N194 PTHR18821:SF7 PROKINETICIN PROKINETICIN-1 endothelial cell proliferation#GO:0001935;cellular process#GO:0009987;cell population proliferation#GO:0008283;epithelial cell proliferation#GO:0050673 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000007461.1|UniProtKB=W5MKZ2 W5MKZ2 TEX49 PTHR35263:SF1 TESTIS-EXPRESSED PROTEIN 49 TESTIS-EXPRESSED PROTEIN 49 LEPOC|Ensembl=ENSLOCG00000014743.1|UniProtKB=W5NBZ6 W5NBZ6 PTHR11547:SF62 ARGININE OR CREATINE KINASE CREATINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000009832.1|UniProtKB=W5MUG4 W5MUG4 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000006328.1|UniProtKB=W5MGX9 W5MGX9 PTHR15735:SF11 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 2 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;trans-synaptic signaling#GO:0099537;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of protein polymerization#GO:0032271;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;neuromuscular junction#GO:0031594 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011257.1|UniProtKB=W5MZM4 W5MZM4 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015394.1|UniProtKB=W5NE83 W5NE83 PTHR24369:SF163 ANTIGEN BSP, PUTATIVE-RELATED MATRIX-REMODELING-ASSOCIATED PROTEIN 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004545.1|UniProtKB=W5MAN7 W5MAN7 PTHR10290:SF5 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cell cycle#GO:0007049;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA topoisomerase#PC00017 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 LEPOC|Ensembl=ENSLOCG00000012171.1|UniProtKB=W5N2W4 W5N2W4 PTHR20930:SF2 OVARIAN CARCINOMA ANTIGEN CA125-RELATED NEXT TO BRCA1 GENE 1 PROTEIN protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009299.1|UniProtKB=W5MSI6 W5MSI6 PTHR24339:SF67 HOMEOBOX PROTEIN EMX-RELATED GNOT1 HOMEODOMAIN PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014692.1|UniProtKB=W5NBS5 W5NBS5 PTHR24073:SF963 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;vacuole organization#GO:0007033;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000003361.1|UniProtKB=W5M6G4 W5M6G4 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000011221.1|UniProtKB=W5MZK5 W5MZK5 PTHR43294:SF9 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009788.1|UniProtKB=W5MUA6 W5MUA6 PTHR24215:SF23 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 1 structural constituent of muscle#GO:0008307;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007520.1|UniProtKB=W5ML64 W5ML64 PTHR23033:SF9 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-A galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002752.1|UniProtKB=W5M4E0 W5M4E0 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001958.1|UniProtKB=W5M1K7 W5M1K7 PTHR47980:SF9 LD44762P RAS-RELATED PROTEIN RAB-3A pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;cell projection organization#GO:0030030;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;cellular anatomical entity morphogenesis#GO:0032989;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;synaptic signaling#GO:0099536;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;establishment of protein localization to extracellular region#GO:0035592;axon development#GO:0061564;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;anatomical structure development#GO:0048856;protein transport#GO:0015031;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;neurotransmitter transport#GO:0006836;signal release#GO:0023061;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;localization#GO:0051179;signal release from synapse#GO:0099643;cell morphogenesis involved in neuron differentiation#GO:0048667;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Rab3A#P05780 LEPOC|Ensembl=ENSLOCG00000011646.1|UniProtKB=W5N0Z5 W5N0Z5 PTHR18945:SF213 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;chloride transmembrane transporter activity#GO:0015108;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015232.1|UniProtKB=W5NDN4 W5NDN4 PTHR16148:SF15 NF-KAPPA-B-REPRESSING FACTOR-RELATED NF-KAPPA-B-REPRESSING FACTOR membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012756.1|UniProtKB=W5N4Z1 W5N4Z1 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009619.1|UniProtKB=W5MTP4 W5MTP4 PTHR46258:SF2 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22C localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000005705.1|UniProtKB=W5MEV2 W5MEV2 PTHR11347:SF98 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000010398.1|UniProtKB=W5MWJ3 W5MWJ3 PTHR10962:SF4 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2B amyloid-beta binding#GO:0001540;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001923.1|UniProtKB=W5M1H0 W5M1H0 PTHR21346:SF2 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 1 process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle disassembly#GO:1903008;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000007370.1|UniProtKB=W5MKN1 W5MKN1 PTHR10589:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000010223.1|UniProtKB=W5MVW1 W5MVW1 PTHR10405:SF15 SPINDLIN SPINDLIN-1 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003881.1|UniProtKB=W5M8C9 W5M8C9 PTHR46376:SF1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000009884.1|UniProtKB=W5MUM0 W5MUM0 PTHR47391:SF1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 LEPOC|Ensembl=ENSLOCG00000001988.1|UniProtKB=W5M1Q8 W5M1Q8 PTHR46071:SF3 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006331.1|UniProtKB=W5MH34 W5MH34 PTHR14340:SF13 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 TITIN structural constituent of muscle#GO:0008307;structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002614.1|UniProtKB=W5M3X1 W5M3X1 PTHR24027:SF311 CADHERIN-23 CADHERIN-22 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000013905.1|UniProtKB=W5N933 W5N933 PTHR19446:SF475 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000007584.1|UniProtKB=W5MLE2 W5MLE2 PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000010817.1|UniProtKB=W5MY10 W5MY10 KDM3A PTHR12549:SF7 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3A histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;histone demethylase activity#GO:0032452;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;demethylase activity#GO:0032451;molecular adaptor activity#GO:0060090;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000003847.1|UniProtKB=W5M887 W5M887 PTHR11588:SF4 TUBULIN TUBULIN DELTA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016209.1|UniProtKB=W5NH77 W5NH77 PTHR13429:SF7 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;apical part of cell#GO:0045177 LEPOC|Ensembl=ENSLOCG00000011598.1|UniProtKB=W5N0U3 W5N0U3 PTHR16267:SF12 BANK1/PIK3AP1 FAMILY MEMBER PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1 protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;signaling receptor binding#GO:0005102 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013523.1|UniProtKB=W5N7R4 W5N7R4 PTHR14952:SF14 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000005172.1|UniProtKB=W5MCX3 W5MCX3 PTHR12011:SF58 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014878.1|UniProtKB=W5NCG2 W5NCG2 PTHR22747:SF14 NUCLEOPLASMIN NUCLEOPLASMIN-2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein-containing complex organization#GO:0043933;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016824.1|UniProtKB=W5NJJ3 W5NJJ3 PTHR11240:SF22 RIBONUCLEASE T2 RIBONUCLEASE T2 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008887.1|UniProtKB=W5MR14 W5MR14 PTHR11827:SF96 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011584.1|UniProtKB=W5N0S4 W5N0S4 PTHR24390:SF263 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 628 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005216.1|UniProtKB=W5MD27 W5MD27 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 LEPOC|Ensembl=ENSLOCG00000000919.1|UniProtKB=W5LY19 W5LY19 PTHR46160:SF9 ALPHA-TECTORIN-RELATED PROTEIN PRY2-RELATED LEPOC|Ensembl=ENSLOCG00000017053.1|UniProtKB=W5NKC5 W5NKC5 PTHR12308:SF20 ANOCTAMIN ANOCTAMIN-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001847.1|UniProtKB=W5M183 W5M183 PTHR18966:SF364 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated channel activity#GO:0022832;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 LEPOC|Ensembl=ENSLOCG00000012275.1|UniProtKB=W5N3A5 W5N3A5 AHCYL1 PTHR23420:SF3 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002233.1|UniProtKB=W5M2K3 W5M2K3 PTHR10972:SF47 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 10 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009857.1|UniProtKB=W5MUJ0 W5MUJ0 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009711.1|UniProtKB=W5MU04 W5MU04 PTHR11636:SF47 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>OCT-1#P06720 LEPOC|Ensembl=ENSLOCG00000011168.1|UniProtKB=W5MZC0 W5MZC0 PTHR12207:SF25 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003496.1|UniProtKB=W5M6Y8 W5M6Y8 PTHR10706:SF130 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 31 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016295.1|UniProtKB=W5NHJ9 W5NHJ9 PTHR24399:SF0 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009713.1|UniProtKB=W5MU10 W5MU10 PTHR45984:SF3 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG SPERM-ASSOCIATED ANTIGEN 1 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;establishment of protein localization to mitochondrion#GO:0072655;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012887.1|UniProtKB=W5N5F5 W5N5F5 PTHR38654:SF1 BUCKY BALL-RELATED BUCKY BALL LEPOC|Ensembl=ENSLOCG00000014612.1|UniProtKB=W5NBJ7 W5NBJ7 PTHR22625:SF32 PLEXIN PLEXIN-A3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015036.1|UniProtKB=W5NCZ5 W5NCZ5 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000005177.1|UniProtKB=W5MCX5 W5MCX5 PTHR36464:SF1 PROTEIN BEAN1 PROTEIN BEAN1 LEPOC|Ensembl=ENSLOCG00000009684.1|UniProtKB=W5MTZ2 W5MTZ2 PTHR24020:SF29 COLLAGEN ALPHA COLLAGEN ALPHA-2(VI) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011301.1|UniProtKB=W5MZT2 W5MZT2 PTHR11610:SF13 LIPASE ENDOTHELIAL LIPASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012500.1|UniProtKB=W5N424 W5N424 PTHR12669:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 3 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014411.1|UniProtKB=W5NAS9 W5NAS9 PTHR26451:SF882 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 11A1-LIKE ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000928.1|UniProtKB=W5LY60 W5LY60 PTHR24044:SF495 NOTCH LIGAND FAMILY MEMBER ATTRACTIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015066.1|UniProtKB=W5ND36 W5ND36 PTHR24046:SF4 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000011296.1|UniProtKB=W5MZU1 W5MZU1 PTHR45622:SF5 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010094.1|UniProtKB=W5MVE8 W5MVE8 PTHR31395:SF5 SHISA PROTEIN SHISA-4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003604.1|UniProtKB=W5M7B1 W5M7B1 PTHR13453:SF1 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000017558.1|UniProtKB=W5NM04 W5NM04 KCTD11 PTHR14499:SF7 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD11 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000876.1|UniProtKB=W5LXX2 W5LXX2 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000015057.1|UniProtKB=W5ND24 W5ND24 PTHR10829:SF12 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;positive regulation of growth#GO:0045927;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;regulation of synapse structure or activity#GO:0050803;positive regulation of multicellular organismal process#GO:0051240;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;regulation of postsynapse organization#GO:0099175;regulation of cell growth#GO:0001558;regulation of anatomical structure size#GO:0090066;postsynapse organization#GO:0099173;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;regulation of cell size#GO:0008361;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000010216.1|UniProtKB=W5MVW5 W5MVW5 PTHR24033:SF151 EGF-LIKE DOMAIN-CONTAINING PROTEIN NOTCH 2 LEPOC|Ensembl=ENSLOCG00000004076.1|UniProtKB=W5M916 W5M916 PTHR45857:SF3 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cell shape#GO:0008360;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007536.1|UniProtKB=W5ML82 W5ML82 PTHR45877:SF7 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH1 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>SIAH-1#G04711;p53 pathway#P00059>Siah#G04696;Wnt signaling pathway#P00057>SIAH-1#P01433;p53 pathway feedback loops 2#P04398>SIAH-1#P04660 LEPOC|Ensembl=ENSLOCG00000016021.1|UniProtKB=W5NGI0 W5NGI0 PTHR22988:SF31 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;actomyosin#GO:0042641;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012876.1|UniProtKB=W5N5E5 W5N5E5 CDH20 PTHR24027:SF84 CADHERIN-23 CADHERIN-20 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000012410.1|UniProtKB=W5N3S1 W5N3S1 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification process#GO:0036211;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000011231.1|UniProtKB=W5MZJ8 W5MZJ8 PTHR45854:SF2 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 Integrin signalling pathway#P00034>ASAP1#P00909 LEPOC|Ensembl=ENSLOCG00000002136.1|UniProtKB=W5M289 W5M289 PTHR10918:SF4 HOMER HOMER PROTEIN HOMOLOG 3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of metal ion transport#GO:0010959;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of monoatomic ion transport#GO:0043269;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015003.1|UniProtKB=W5NCW4 W5NCW4 PTHR24038:SF0 STABILIN STABILIN-2 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016550.1|UniProtKB=W5NII8 W5NII8 PTHR24075:SF6 SEC63 DOMAIN-CONTAINING ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3 ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005166.1|UniProtKB=W5MCW5 W5MCW5 PTHR24072:SF99 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOF GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000001542.1|UniProtKB=W5M062 W5M062 PTHR11819:SF145 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008315.1|UniProtKB=W5MNZ2 W5MNZ2 PTHR28658:SF1 TRANSMEMBRANE PROTEIN 180 MAJOR FACILITATOR SUPERFAMILY DOMAIN CONTAINING 13B LEPOC|Ensembl=ENSLOCG00000016502.1|UniProtKB=W5NIC5 W5NIC5 C11orf98 PTHR14554:SF1 GENE, 49416-RELATED CHROMOSOME 11 OPEN READING FRAME 98 LEPOC|Ensembl=ENSLOCG00000012913.1|UniProtKB=W5N5J6 W5N5J6 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013578.1|UniProtKB=W5N7Y3 W5N7Y3 PTHR48112:SF3 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000005422.1|UniProtKB=W5MDT4 W5MDT4 PTHR45616:SF21 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 7 structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;skin development#GO:0043588;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;epidermis development#GO:0008544;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;intermediate filament organization#GO:0045109;multicellular organismal process#GO:0032501;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;extracellular region#GO:0005576;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;extracellular space#GO:0005615;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;keratin filament#GO:0045095;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000004374.1|UniProtKB=W5MA38 W5MA38 PTHR11905:SF20 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 8 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of locomotion#GO:0040012;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of protein catabolic process#GO:0042176;positive regulation of proteolysis#GO:0045862;inflammatory response#GO:0006954;positive regulation of leukocyte migration#GO:0002687;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;positive regulation of metabolic process#GO:0009893;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of immune system process#GO:0002682;defense response#GO:0006952;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of proteolysis#GO:0030162;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;positive regulation of immune system process#GO:0002684;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005846.1|UniProtKB=W5MFC2 W5MFC2 PTHR45860:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001245.1|UniProtKB=W5LZ53 W5LZ53 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000018294.1|UniProtKB=W5NP36 W5NP36 PTHR22750:SF17 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014873.1|UniProtKB=W5NCF9 W5NCF9 PTHR11866:SF7 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTACYCLIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000017230.1|UniProtKB=W5NL02 W5NL02 PTHR15629:SF2 SH3YL1 PROTEIN SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011265.1|UniProtKB=W5MZN1 W5MZN1 PTHR24028:SF114 CADHERIN-87A PCDH2G3 PROTEIN-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000008011.1|UniProtKB=W5MMX4 W5MMX4 PTHR45161:SF2 CYTOSKELETON-ASSOCIATED PROTEIN 4 RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 LEPOC|Ensembl=ENSLOCG00000014035.1|UniProtKB=W5N9J5 W5N9J5 PTHR13104:SF0 MED-6-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000009227.1|UniProtKB=W5MS97 W5MS97 PTHR15377:SF7 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;RNA polymerase binding#GO:0070063;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;enzyme binding#GO:0019899 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000010167.1|UniProtKB=W5MVN5 W5MVN5 SNAPC1 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 LEPOC|Ensembl=ENSLOCG00000017587.1|UniProtKB=W5NM33 W5NM33 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000017030.1|UniProtKB=W5NK92 W5NK92 PTHR24082:SF197 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of inflammatory response#GO:0050728;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;negative regulation of defense response#GO:0031348;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;negative regulation of nitrogen compound metabolic process#GO:0051172;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of response to stress#GO:0080134;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;positive regulation of RNA metabolic process#GO:0051254;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744 LEPOC|Ensembl=ENSLOCG00000009489.1|UniProtKB=W5MT87 W5MT87 PTHR14247:SF10 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein modification process#GO:0031401;positive regulation of cellular process#GO:0048522;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000007968.1|UniProtKB=W5MMS7 W5MMS7 PTHR23226:SF160 ZINC FINGER AND SCAN DOMAIN-CONTAINING PLURIPOTENCY ASSOCIATED TRANSCRIPT 25-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007664.1|UniProtKB=W5MLR3 W5MLR3 PTHR11243:SF14 GROWTH FACTOR RECEPTOR-BOUND PROTEIN AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN cytoplasm#GO:0005737;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002266.1|UniProtKB=W5M2R3 W5M2R3 PTHR24291:SF120 CYTOCHROME P450 FAMILY 4 SI:DKEY-91I10.3 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;cholesterol metabolic process#GO:0008203;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016409.1|UniProtKB=W5NI04 W5NI04 AMIGO2 PTHR24369:SF213 ANTIGEN BSP, PUTATIVE-RELATED INSULIN LIKE GROWTH FACTOR BINDING PROTEIN ACID LABILE SUBUNIT cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016709.1|UniProtKB=W5NJ33 W5NJ33 PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000009086.1|UniProtKB=W5MRS5 W5MRS5 TNFRSF11B PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003257.1|UniProtKB=W5M641 W5M641 RAB11FIP3 PTHR15726:SF6 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 3 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of cell division#GO:0051302;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of cytokinesis#GO:0032465 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;midbody#GO:0030496;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell division site#GO:0032153;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011698.1|UniProtKB=W5N166 W5N166 PTHR31921:SF1 PROTEIN DPCD PROTEIN DPCD LEPOC|Ensembl=ENSLOCG00000002242.1|UniProtKB=W5M2K2 W5M2K2 PTHR44888:SF2 HEPACAM FAMILY MEMBER 2-RELATED HEPATIC AND GLIAL CELL ADHESION MOLECULE LEPOC|Ensembl=ENSLOCG00000014359.1|UniProtKB=W5NAM1 W5NAM1 PTHR12125:SF1 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 50 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 carbohydrate derivative metabolic process#GO:1901135;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015248.1|UniProtKB=W5NDQ4 W5NDQ4 PTHR12439:SF33 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 LEPOC|Ensembl=ENSLOCG00000011406.1|UniProtKB=W5N062 W5N062 RAB29 PTHR24073:SF315 DRAB5-RELATED RAS-RELATED PROTEIN RAB-7L1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000008815.1|UniProtKB=W5MQS3 W5MQS3 PTHR48041:SF49 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE TRANSPORTER SUB-FAMILY G MEMBER 2B-RELATED transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016876.1|UniProtKB=W5NJQ1 W5NJQ1 PTHR12668:SF11 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14A regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017769.1|UniProtKB=W5NML4 W5NML4 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYLTRANSFERASE 1, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002294.1|UniProtKB=W5M2U5 W5M2U5 PTHR24416:SF136 TYROSINE-PROTEIN KINASE RECEPTOR BDNF_NT-3 GROWTH FACTORS RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to endogenous stimulus#GO:0009719;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007451.1|UniProtKB=W5MKZ1 W5MKZ1 STK32C PTHR24356:SF153 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007455.1|UniProtKB=W5MKY7 W5MKY7 PTHR23295:SF5 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED SI:CH211-216L23.2 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000000701.1|UniProtKB=W5LXB9 W5LXB9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014473.1|UniProtKB=W5NB07 W5NB07 PTHR31233:SF12 BICAUDAL D FAMILY MEMBER BICAUDAL D HOMOLOG 2-LIKE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011251.1|UniProtKB=W5MZL4 W5MZL4 C14orf28 PTHR35350:SF1 HYPOTHETICAL LOC314168 HYPOTHETICAL LOC314168 LEPOC|Ensembl=ENSLOCG00000003151.1|UniProtKB=W5M5R4 W5M5R4 PTHR11347:SF29 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000008655.1|UniProtKB=W5MQ70 W5MQ70 PTHR23510:SF16 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010148.1|UniProtKB=W5MVL7 W5MVL7 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;cyclase activity#GO:0009975;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000084.1|UniProtKB=W5LVD8 W5LVD8 PTHR13593:SF113 FAMILY NOT NAMED SI:DKEY-266F7.9 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 LEPOC|Ensembl=ENSLOCG00000000720.1|UniProtKB=W5LXE3 W5LXE3 PTHR45781:SF5 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 2 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000002879.1|UniProtKB=W5M4T3 W5M4T3 SRRM3 PTHR34755:SF2 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 LEPOC|Ensembl=ENSLOCG00000004012.1|UniProtKB=W5M8T3 W5M8T3 PTHR23037:SF42 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT GAMMA ISOFORM X1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immunoglobulin mediated immune response#GO:0016064;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;leukocyte mediated immunity#GO:0002443;cell communication#GO:0007154;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013794.1|UniProtKB=W5N8Q9 W5N8Q9 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000014831.1|UniProtKB=W5NCA4 W5NCA4 PTHR11375:SF1 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001798.1|UniProtKB=W5M134 W5M134 PTHR11679:SF35 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 1 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Munc18#P05770 LEPOC|Ensembl=ENSLOCG00000004553.1|UniProtKB=W5MAP2 W5MAP2 PTHR13865:SF11 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cellular localization#GO:0051641;macromolecule localization#GO:0033036;epithelium development#GO:0060429;system process#GO:0003008;developmental process#GO:0032502;cell differentiation#GO:0030154;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;anatomical structure homeostasis#GO:0060249;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;homeostatic process#GO:0042592;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;circulatory system process#GO:0003013;protein localization#GO:0008104;cell development#GO:0048468;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446 anchoring junction#GO:0070161;tight junction#GO:0070160;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000005181.1|UniProtKB=W5MCX7 W5MCX7 PTHR11615:SF322 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 3 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011195.1|UniProtKB=W5MZE5 W5MZE5 PTHR11374:SF63 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007440.1|UniProtKB=W5MKW8 W5MKW8 PTHR12418:SF19 ACYL-COENZYME A THIOESTERASE THEM4 ACYL-COENZYME A THIOESTERASE THEM4 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000005487.1|UniProtKB=W5ME10 W5ME10 RBBP6 PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017692.1|UniProtKB=W5NMD8 W5NMD8 PTHR46229:SF2 BOLA TRANSCRIPTION REGULATOR BOLA-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011384.1|UniProtKB=W5N035 W5N035 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016704.1|UniProtKB=W5NJ38 W5NJ38 ELAPOR2 PTHR22727:SF3 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR FAMILY MEMBER 2 regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004711.1|UniProtKB=W5MB86 W5MB86 PTHR24404:SF46 ZINC FINGER PROTEIN ZINC FINGER PROTEIN GFI-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009504.1|UniProtKB=W5MTB8 W5MTB8 PTHR43066:SF14 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 4 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002711.1|UniProtKB=W5M470 W5M470 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016527.1|UniProtKB=W5NIF6 W5NIF6 PTHR21477:SF13 ZGC:172139 KIAA0930 LEPOC|Ensembl=ENSLOCG00000013646.1|UniProtKB=W5N866 W5N866 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZGC:112524 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;cellular anatomical entity#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011546.1|UniProtKB=W5N0M6 W5N0M6 PTHR31025:SF28 SI:CH211-196P9.1-RELATED SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000012550.1|UniProtKB=W5N497 W5N497 PTHR10218:SF231 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN) ALPHA V1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012015.1|UniProtKB=W5N2E9 W5N2E9 DNAJC13 PTHR36983:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002081.1|UniProtKB=W5M207 W5M207 PTHR12610:SF23 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 2 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005638.1|UniProtKB=W5MEJ8 W5MEJ8 PTHR31169:SF24 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 7 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014541.1|UniProtKB=W5NB93 W5NB93 PTHR13693:SF58 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, ERYTHROID-SPECIFIC, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;developmental process#GO:0032502;porphyrin-containing compound metabolic process#GO:0006778;biosynthetic process#GO:0009058;heme biosynthetic process#GO:0006783;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;pigment biosynthetic process#GO:0046148;protein metabolic process#GO:0019538;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;erythrocyte differentiation#GO:0030218;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cell development#GO:0048468;immune system process#GO:0002376;anatomical structure development#GO:0048856;multicellular organismal-level homeostasis#GO:0048871;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001074.1|UniProtKB=W5LYJ9 W5LYJ9 PTHR15663:SF4 COMM DOMAIN-CONTAINING PROTEIN 9 COMM DOMAIN-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000012431.1|UniProtKB=W5N3U8 W5N3U8 GALNT10 PTHR11675:SF41 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 10 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007740.1|UniProtKB=W5MLY9 W5MLY9 PTHR11394:SF137 TASTE RECEPTOR TYPE 2 C-X-C CHEMOKINE RECEPTOR TYPE 3 ISOFORM X1-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003535.1|UniProtKB=W5M723 W5M723 PTHR43918:SF5 ACETYLCHOLINESTERASE CHOLINESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 esterase#PC00097;hydrolase#PC00121 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 LEPOC|Ensembl=ENSLOCG00000012290.1|UniProtKB=W5N3B0 W5N3B0 PTHR22792:SF43 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002173.1|UniProtKB=W5M2C0 W5M2C0 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002430.1|UniProtKB=W5M392 W5M392 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE LEPOC|Ensembl=ENSLOCG00000005911.1|UniProtKB=W5MFI0 W5MFI0 PTHR43691:SF8 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 LEPOC|Ensembl=ENSLOCG00000010429.1|UniProtKB=W5MWM3 W5MWM3 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000002420.1|UniProtKB=W5M382 W5M382 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006700.1|UniProtKB=W5MI83 W5MI83 PTHR15902:SF2 NEURITIN-RELATED NEURITIN-LIKE PROTEIN cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;neurogenesis#GO:0022008;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;growth#GO:0040007;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;cell growth#GO:0016049;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013496.1|UniProtKB=W5N7N4 W5N7N4 PTHR15852:SF11 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN SSU-2 HOMOLOG, TANDEM DUPLICATE 2 LEPOC|Ensembl=ENSLOCG00000003545.1|UniProtKB=W5M731 W5M731 PTHR23085:SF7 GH28348P JUNCTOPHILIN-3 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of synaptic plasticity#GO:0048167 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016536.1|UniProtKB=W5NIG5 W5NIG5 PTHR12101:SF17 POPEYE DOMAIN CONTAINING PROTEIN BLOOD VESSEL EPICARDIAL SUBSTANCE nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 LEPOC|Ensembl=ENSLOCG00000017950.1|UniProtKB=W5NN44 W5NN44 PTHR16008:SF6 F-BOX ONLY PROTEIN 4 SI:DKEY-12E7.1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000000128.1|UniProtKB=W5LVJ7 W5LVJ7 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000017955.1|UniProtKB=W5NN49 W5NN49 PTHR11863:SF104 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE-LIKE PROTEIN 1, MEMBER 1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;steroid biosynthetic process#GO:0006694;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016246.1|UniProtKB=W5NHC3 W5NHC3 PTHR24073:SF509 DRAB5-RELATED RAS-RELATED PROTEIN RAB-21 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013011.1|UniProtKB=W5N5W8 W5N5W8 OTUB2 PTHR12931:SF15 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUBAIN-LIKE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000300.1|UniProtKB=W5LW64 W5LW64 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005424.1|UniProtKB=W5MDT2 W5MDT2 PTHR46484:SF1 SI:CH211-171H4.5-RELATED SCHWANN CELL MYELIN PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000012096.1|UniProtKB=W5N2M9 W5N2M9 PTHR11109:SF11 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 LEPOC|Ensembl=ENSLOCG00000004453.1|UniProtKB=W5MAB3 W5MAB3 PTHR43625:SF4 AFLATOXIN B1 ALDEHYDE REDUCTASE ALDO-KETO REDUCTASE FAMILY 7 LIKE (GENE_PSEUDOGENE) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007498.1|UniProtKB=W5ML43 W5ML43 PTHR12125:SF11 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 carbohydrate derivative metabolic process#GO:1901135;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008599.1|UniProtKB=W5MQ00 W5MQ00 PTHR24125:SF0 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A LEPOC|Ensembl=ENSLOCG00000014292.1|UniProtKB=W5NAE3 W5NAE3 PTHR11085:SF6 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017509.1|UniProtKB=W5NLV5 W5NLV5 PTHR20889:SF2 PHOSPHATASE, ORPHAN 1, 2 PHOSPHOETHANOLAMINE_PHOSPHOCHOLINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000003960.1|UniProtKB=W5M8P4 W5M8P4 PTHR21637:SF5 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 10 regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of phosphorylation#GO:0042327;regulation of phosphate metabolic process#GO:0019220;positive regulation of metabolic process#GO:0009893;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;positive regulation of cellular metabolic process#GO:0031325;biological regulation#GO:0065007;positive regulation of phosphorus metabolic process#GO:0010562;regulation of phosphorylation#GO:0042325;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010354.1|UniProtKB=W5MWD0 W5MWD0 PTHR24347:SF391 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN DEPENDENT PROTEIN KINASE IV transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014910.1|UniProtKB=W5NCK0 W5NCK0 PTHR19354:SF5 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 1-RELATED regulation of cell communication#GO:0010646;regulation of dendrite development#GO:0050773;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of synaptic plasticity#GO:0048167;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;dendritic spine#GO:0043197 LEPOC|Ensembl=ENSLOCG00000010452.1|UniProtKB=W5MWQ9 W5MWQ9 PTHR15288:SF6 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2C guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001925.1|UniProtKB=W5M1I1 W5M1I1 PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002077.1|UniProtKB=W5M214 W5M214 VWA5B1 PTHR46299:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B1 LEPOC|Ensembl=ENSLOCG00000016335.1|UniProtKB=W5NHQ6 W5NHQ6 PTHR24072:SF13 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOQ GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052;cortical actin cytoskeleton organization#GO:0030866 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Rac#P00564;Huntington disease#P00029>Rac#P00775 LEPOC|Ensembl=ENSLOCG00000005202.1|UniProtKB=W5MD07 W5MD07 PTHR11254:SF127 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of dendrite development#GO:0050773;negative regulation of biological process#GO:0048519;regulation of sodium ion transport#GO:0002028;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;regulation of metal ion transport#GO:0010959;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of monoatomic cation transmembrane transport#GO:1904062;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;organic substance catabolic process#GO:1901575;regulation of transporter activity#GO:0032409;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of transport#GO:0051051;regulation of plasma membrane bounded cell projection organization#GO:0120035;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron projection development#GO:0010975;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014156.1|UniProtKB=W5N9X8 W5N9X8 PTHR10383:SF5 SERINE INCORPORATOR SERINE INCORPORATOR 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005591.1|UniProtKB=W5MEE3 W5MEE3 PTHR24366:SF39 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT, IG-LIKE AND TRANSMEMBRANE DOMAINS 2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000002905.1|UniProtKB=W5M4V4 W5M4V4 PTHR14511:SF9 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER B protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein kinase regulator activity#GO:0019887;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004145.1|UniProtKB=W5M999 W5M999 PTHR23292:SF45 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001477.1|UniProtKB=W5LZY6 W5LZY6 PISD PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 decarboxylase#PC00089 LEPOC|Ensembl=ENSLOCG00000000545.1|UniProtKB=W5LWY3 W5LWY3 PTHR11003:SF21 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009264.1|UniProtKB=W5MSD8 W5MSD8 PTHR21415:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015201.1|UniProtKB=W5NDJ7 W5NDJ7 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 monocarboxylic acid transport#GO:0015718;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;lipid localization#GO:0010876;monoatomic ion transport#GO:0006811 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002901.1|UniProtKB=W5M4W0 W5M4W0 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008785.1|UniProtKB=W5MQN5 W5MQN5 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004025.1|UniProtKB=W5M8V5 W5M8V5 AFF1 PTHR10528:SF6 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 1 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017435.1|UniProtKB=W5NLN1 W5NLN1 PTHR12002:SF174 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000012287.1|UniProtKB=W5N3B4 W5N3B4 DLL4 PTHR24044:SF320 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 LEPOC|Ensembl=ENSLOCG00000012247.1|UniProtKB=W5N362 W5N362 PTHR43272:SF107 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 5 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008836.1|UniProtKB=W5MQU5 W5MQU5 PTHR46059:SF3 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002150.1|UniProtKB=W5M2B5 W5M2B5 TGM4 PTHR11590:SF70 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013688.1|UniProtKB=W5N8C5 W5N8C5 PTHR13466:SF2 TEX2 PROTEIN-RELATED TESTIS-EXPRESSED PROTEIN 2 lipid binding#GO:0008289;binding#GO:0005488 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007979.1|UniProtKB=W5MMW4 W5MMW4 PTHR46961:SF13 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 3 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005810.1|UniProtKB=W5MF56 W5MF56 PTHR24205:SF5 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 3 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012463.1|UniProtKB=W5N3Y5 W5N3Y5 PTHR22012:SF2 FIBROUS SHEATH INTERACTING PROTEIN 1 FIBROUS SHEATH-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000018210.1|UniProtKB=W5NNV2 W5NNV2 PTHR19290:SF86 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;sensory system development#GO:0048880;visual system development#GO:0150063;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004520.1|UniProtKB=W5MAK2 W5MAK2 EIF3M PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003254.1|UniProtKB=W5M640 W5M640 PTHR21964:SF34 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000003076.1|UniProtKB=W5M5G5 W5M5G5 PTHR48043:SF140 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 LEPOC|Ensembl=ENSLOCG00000016406.1|UniProtKB=W5NI01 W5NI01 PTHR24034:SF43 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488;transforming growth factor beta binding#GO:0050431;cytokine binding#GO:0019955 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003194.1|UniProtKB=W5M5W7 W5M5W7 PTHR12801:SF152 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000009906.1|UniProtKB=W5MUP8 W5MUP8 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000016931.1|UniProtKB=W5NJX1 W5NJX1 PTHR24020:SF90 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXI) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003928.1|UniProtKB=W5M8I7 W5M8I7 PTHR24114:SF31 LEUCINE RICH REPEAT FAMILY PROTEIN NLR FAMILY MEMBER X1 LEPOC|Ensembl=ENSLOCG00000014080.1|UniProtKB=W5N9P4 W5N9P4 C17orf49 PTHR21397:SF2 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED CHROMATIN COMPLEXES SUBUNIT BAP18 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004163.1|UniProtKB=W5M9B9 W5M9B9 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 Apoptosis signaling pathway#P00006>endoG#P00279 LEPOC|Ensembl=ENSLOCG00000002938.1|UniProtKB=W5M526 W5M526 PTHR22619:SF2 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 5 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000009588.1|UniProtKB=W5MTK7 W5MTK7 PTHR10253:SF5 POLYCOMB PROTEIN POLYCOMB PROTEIN EED nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;heterochromatin formation#GO:0031507;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015512.1|UniProtKB=W5NEN4 W5NEN4 PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004109.1|UniProtKB=W5M961 W5M961 PTHR24056:SF254 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 2 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>ERK1-2#P00543;p53 pathway#P00059>Cdc2#P04634;p53 pathway feedback loops 2#P04398>cdk2#P04653;p53 pathway#P00059>Cdk2#P04625 LEPOC|Ensembl=ENSLOCG00000011019.1|UniProtKB=W5MYS4 W5MYS4 PTHR40710:SF1 RIKEN CDNA E230025N22 GENE RIKEN CDNA E230025N22 GENE LEPOC|Ensembl=ENSLOCG00000000030.1|UniProtKB=W5LV78 W5LV78 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002861.1|UniProtKB=W5M4T0 W5M4T0 PTHR22922:SF3 GPI-ANCHORED PROTEIN P137 CAPRIN-1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010078.1|UniProtKB=W5MVB9 W5MVB9 PTHR28450:SF1 FANCONI ANEMIA GROUP B PROTEIN FANCONI ANEMIA GROUP B PROTEIN DNA repair#GO:0006281;regulation of double-strand break repair#GO:2000779;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;positive regulation of DNA repair#GO:0045739;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;regulation of DNA metabolic process#GO:0051052;negative regulation of DNA repair#GO:0045738;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;DNA metabolic process#GO:0006259 Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006008.1|UniProtKB=W5MFV1 W5MFV1 PTHR12289:SF30 METAXIN RELATED METAXIN-3 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017623.1|UniProtKB=W5NM69 W5NM69 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000788.1|UniProtKB=W5LXL8 W5LXL8 PTHR15505:SF3 RIIA DOMAIN-CONTAINING PROTEIN 1 CILIOGENESIS-ASSOCIATED TTC17-INTERACTING PROTEIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 LEPOC|Ensembl=ENSLOCG00000006542.1|UniProtKB=W5MHQ1 W5MHQ1 PTHR23053:SF0 DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1 HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000011456.1|UniProtKB=W5N0B6 W5N0B6 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4-LIKE ISOFORM X1 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000003670.1|UniProtKB=W5M7L0 W5M7L0 PTHR14383:SF6 SWAP-70 RECOMBINASE SWITCH-ASSOCIATED PROTEIN 70 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000244.1|UniProtKB=W5LVW1 W5LVW1 PTHR11818:SF103 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN 'GREEK KEY' DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002256.1|UniProtKB=W5M2M5 W5M2M5 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001989.1|UniProtKB=W5M1U6 W5M1U6 PTHR22988:SF33 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;macromolecule modification#GO:0043412;developmental process#GO:0032502;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;protein metabolic process#GO:0019538;cytokinesis#GO:0000910;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;embryo development#GO:0009790;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;actin cytoskeleton organization#GO:0030036;embryonic morphogenesis#GO:0048598;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>ROCK#P00881;CCKR signaling map#P06959>ROCK1#P07033;Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 LEPOC|Ensembl=ENSLOCG00000004228.1|UniProtKB=W5M9K3 W5M9K3 PTHR10190:SF5 EYES ABSENT EYES ABSENT HOMOLOG 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of DNA repair#GO:0045739;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of DNA repair#GO:0006282;regulation of biological process#GO:0050789;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of response to stress#GO:0080134;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000017902.1|UniProtKB=W5NMZ6 W5NMZ6 PTHR17575:SF1 UROCORTIN-2 AND 3 UROCORTIN-3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000004773.1|UniProtKB=W5MBH7 W5MBH7 PTHR23257:SF716 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>KSR-1#P06842 LEPOC|Ensembl=ENSLOCG00000003772.1|UniProtKB=W5M7Y8 W5M7Y8 PTHR11818:SF119 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN D structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002419.1|UniProtKB=W5M386 W5M386 PTHR18853:SF7 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005557.1|UniProtKB=W5MEA0 W5MEA0 PTHR13850:SF2 PLEIOTROPHIN FAMILY MEMBER MIDKINE molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000013013.1|UniProtKB=W5N5X3 W5N5X3 PTHR10353:SF68 GLYCOSYL HYDROLASE BETA-KLOTHO hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009725.1|UniProtKB=W5MU26 W5MU26 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011306.1|UniProtKB=W5MZT6 W5MZT6 PTHR46493:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009600.1|UniProtKB=W5MTM4 W5MTM4 SLC49A3 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014063.1|UniProtKB=W5N9M0 W5N9M0 PTHR47403:SF3 LOC100145250 PROTEIN N-ACETYLTRANSFERASE 16-RELATED LEPOC|Ensembl=ENSLOCG00000011184.1|UniProtKB=W5MZD2 W5MZD2 PTHR46908:SF4 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN LEPOC|Ensembl=ENSLOCG00000015189.1|UniProtKB=W5NDI5 W5NDI5 PTHR12103:SF18 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003534.1|UniProtKB=W5M725 W5M725 PTHR15860:SF2 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN RING FINGER AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 LEPOC|Ensembl=ENSLOCG00000015431.1|UniProtKB=W5NED2 W5NED2 PTHR23257:SF750 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 21 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013893.1|UniProtKB=W5N920 W5N920 PTHR19143:SF263 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;regulation of immune response#GO:0050776;regulation of T cell activation#GO:0050863;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell activation#GO:0050866;negative regulation of cell adhesion#GO:0007162;regulation of response to stimulus#GO:0048583;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;regulation of cellular process#GO:0050794;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008894.1|UniProtKB=W5MR35 W5MR35 LVRN PTHR11533:SF31 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE Q metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008772.1|UniProtKB=W5MQL9 W5MQL9 SRFBP1 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005119.1|UniProtKB=W5MCQ2 W5MCQ2 PTHR11486:SF31 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 4 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000015740.1|UniProtKB=W5NFH2 W5NFH2 PTHR11878:SF6 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 1 calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;axon#GO:0030424;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014295.1|UniProtKB=W5NAF5 W5NAF5 PTHR42776:SF1 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001839.1|UniProtKB=W5M190 W5M190 PTHR43788:SF9 DNA2/NAM7 HELICASE FAMILY MEMBER HELICASE WITH ZINC FINGER DOMAIN 2 catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002916.1|UniProtKB=W5M4X8 W5M4X8 PTHR44793:SF1 MATRIX REMODELING-ASSOCIATED PROTEIN 8 MATRIX REMODELING-ASSOCIATED PROTEIN 8 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008523.1|UniProtKB=W5MPR0 W5MPR0 PTHR16295:SF19 TRAF-TYPE ZINC FINGER PROTEIN-RELATED TRAF-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of innate immune response#GO:0045824;negative regulation of response to stimulus#GO:0048585;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;negative regulation of defense response#GO:0031348;regulation of response to biotic stimulus#GO:0002831;regulation of biological process#GO:0050789;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of immune system process#GO:0002682 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013487.1|UniProtKB=W5N7L8 W5N7L8 PKIA PTHR15416:SF2 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000018033.1|UniProtKB=W5NNC5 W5NNC5 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016181.1|UniProtKB=W5NH40 W5NH40 PTHR12157:SF18 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 1 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 LEPOC|Ensembl=ENSLOCG00000004022.1|UniProtKB=W5M8U5 W5M8U5 PTHR24161:SF118 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012818.1|UniProtKB=W5N581 W5N581 PTHR13817:SF59 TITIN PROTEIN SIDEKICK-2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007250.1|UniProtKB=W5MK66 W5MK66 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010651.1|UniProtKB=W5MXE8 W5MXE8 PTHR18884:SF54 SEPTIN SEPTIN-8 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000014054.1|UniProtKB=W5N9L4 W5N9L4 PTHR12377:SF2 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;gene expression#GO:0010467;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000007252.1|UniProtKB=W5MK67 W5MK67 PTHR24412:SF475 KELCH PROTEIN KELCH-LIKE PROTEIN 17 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012172.1|UniProtKB=W5N2X2 W5N2X2 PTHR11063:SF8 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 Proline biosynthesis#P02768>Glutamate semialdehyde dehydrogenase#P03112 LEPOC|Ensembl=ENSLOCG00000014477.1|UniProtKB=W5NB17 W5NB17 PTHR12103:SF19 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001664.1|UniProtKB=W5M0L0 W5M0L0 PTHR24103:SF686 E3 UBIQUITIN-PROTEIN LIGASE TRIM B30.2_SPRY DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000018066.1|UniProtKB=W5NNF8 W5NNF8 PTHR14499:SF68 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD8 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277 receptor complex#GO:0043235;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017477.1|UniProtKB=W5NLS3 W5NLS3 PTHR31046:SF0 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 LEPOC|Ensembl=ENSLOCG00000001351.1|UniProtKB=W5LZI1 W5LZI1 PTHR10130:SF1 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEX5-RELATED PROTEIN signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011589.1|UniProtKB=W5N0T4 W5N0T4 GRSF1 PTHR13976:SF91 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED G-RICH RNA SEQUENCE-BINDING FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004926.1|UniProtKB=W5MC13 W5MC13 PTHR10496:SF0 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014452.1|UniProtKB=W5NAX8 W5NAX8 PTHR46961:SF11 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN LINKER DOMAIN-CONTAINING PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018265.1|UniProtKB=W5NP07 W5NP07 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012485.1|UniProtKB=W5N411 W5N411 PTHR21319:SF53 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 P53 pathway feedback loops 1#P04392>Pirh-2#P04538;P53 pathway feedback loops 1#P04392>Pirh-2#G04684 LEPOC|Ensembl=ENSLOCG00000012793.1|UniProtKB=W5N535 W5N535 PTHR12013:SF0 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN localization#GO:0051179;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001041.1|UniProtKB=W5LYG2 W5LYG2 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006552.1|UniProtKB=W5MHQ8 W5MHQ8 PTHR45638:SF2 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-4 monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;ligand-gated monoatomic cation channel activity#GO:0099094;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015089.1|UniProtKB=W5ND67 W5ND67 PTHR24418:SF197 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FES_FPS protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to chemical#GO:0042221;cell adhesion#GO:0007155;cellular process#GO:0009987;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by semaphorins#P00007>Fes#P00332 LEPOC|Ensembl=ENSLOCG00000009731.1|UniProtKB=W5MU24 W5MU24 PTHR10665:SF3 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;Notch signaling pathway#GO:0007219 protein-containing complex#GO:0032991 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Notch signaling pathway#P00045>Su(H)#P01101;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Angiogenesis#P00005>CSL#P00233 LEPOC|Ensembl=ENSLOCG00000014512.1|UniProtKB=W5NB51 W5NB51 PTHR24410:SF10 HL07962P-RELATED KELCH-LIKE PROTEIN 25 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007843.1|UniProtKB=W5MMA8 W5MMA8 HBE1 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT EPSILON antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000001603.1|UniProtKB=W5M0E1 W5M0E1 PTHR13869:SF7 MYELIN P0 RELATED MYELIN PROTEIN P0 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013692.1|UniProtKB=W5N8C3 W5N8C3 PTHR11599:SF62 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000000132.1|UniProtKB=W5LVL1 W5LVL1 PTHR12385:SF37 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 4 transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic cation transport#GO:0015695;transport#GO:0006810;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000454.1|UniProtKB=W5LWN4 W5LWN4 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;chaperone-mediated protein complex assembly#GO:0051131;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016684.1|UniProtKB=W5NJ03 W5NJ03 PTHR11416:SF7 PRO-OPIOMELANOCORTIN PRO-OPIOMELANOCORTIN Opioid proopiomelanocortin pathway#P05917>proopiomelanocortin#P06010;Opioid proopiomelanocortin pathway#P05917>ACTH#P06008;Opioid proopiomelanocortin pathway#P05917>alpha-MSH#P06007;Cortocotropin releasing factor receptor signaling pathway#P04380>ACTH#P04453;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#G04671;Opioid proopiomelanocortin pathway#P05917>beta-Endorphin#P06006;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#P04452;Cortocotropin releasing factor receptor signaling pathway#P04380>beta-endorphin#P04455 LEPOC|Ensembl=ENSLOCG00000016336.1|UniProtKB=W5NHQ8 W5NHQ8 PTHR10812:SF5 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-DELTA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016050.1|UniProtKB=W5NGL2 W5NGL2 PTHR22957:SF255 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22A nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009870.1|UniProtKB=W5MUL5 W5MUL5 PTHR24257:SF22 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3B hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008647.1|UniProtKB=W5MQ61 W5MQ61 PTHR22803:SF74 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED SECRETORY PHOSPHOLIPASE A2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 receptor complex#GO:0043235;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000005889.1|UniProtKB=W5MFF6 W5MFF6 PTHR10024:SF250 SYNAPTOTAGMIN SYNAPTOTAGMIN-13 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000006002.1|UniProtKB=W5MFU3 W5MFU3 PTHR18841:SF0 VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010964.1|UniProtKB=W5MYK7 W5MYK7 PTHR22802:SF394 C-TYPE LECTIN SUPERFAMILY MEMBER COLLECTIN-12 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013874.1|UniProtKB=W5N906 W5N906 PTHR28583:SF1 ACID AMIDASE ACID CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016540.1|UniProtKB=W5NIG8 W5NIG8 PTHR11254:SF363 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HACE1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;membrane organization#GO:0061024;protein catabolic process#GO:0030163;endomembrane system organization#GO:0010256;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017733.1|UniProtKB=W5NMH8 W5NMH8 PTHR21255:SF55 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 4 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001581.1|UniProtKB=W5M0A5 W5M0A5 PTHR11905:SF258 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN PEPTIDASE M12B DOMAIN-CONTAINING PROTEIN metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005817.1|UniProtKB=W5MF67 W5MF67 PTHR15822:SF4 TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN TYROSYL-DNA PHOSPHODIESTERASE 2 LEPOC|Ensembl=ENSLOCG00000002465.1|UniProtKB=W5M3E0 W5M3E0 PTHR10742:SF393 FLAVIN MONOAMINE OXIDASE SPERMINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;nitrogen compound metabolic process#GO:0006807;biogenic amine metabolic process#GO:0006576;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;polyamine catabolic process#GO:0006598;polyamine metabolic process#GO:0006595;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014396.1|UniProtKB=W5NAR9 W5NAR9 PTHR10878:SF8 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;chordate embryonic development#GO:0043009;response to stimulus#GO:0050896;embryo development#GO:0009790;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Wnt signaling pathway#P00057>Dishevelled#P01447 LEPOC|Ensembl=ENSLOCG00000011734.1|UniProtKB=W5N1C1 W5N1C1 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009199.1|UniProtKB=W5MS65 W5MS65 PTHR13025:SF8 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN FAMILY, MEMBER D1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000007616.1|UniProtKB=W5MLH8 W5MLH8 PTHR11267:SF28 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate specification#GO:0001708;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;cellular developmental process#GO:0048869;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000015096.1|UniProtKB=W5ND71 W5ND71 PTHR46070:SF3 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5B nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 LEPOC|Ensembl=ENSLOCG00000017635.1|UniProtKB=W5NM81 W5NM81 PTHR24369:SF207 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT AND IG DOMAIN CONTAINING 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006007.1|UniProtKB=W5MFW3 W5MFW3 PTHR46877:SF16 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 10 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001911.1|UniProtKB=W5M1E7 W5M1E7 PTHR15416:SF5 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR GAMMA protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000013739.1|UniProtKB=W5N8I1 W5N8I1 PTHR45840:SF5 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 3 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 LEPOC|Ensembl=ENSLOCG00000005484.1|UniProtKB=W5ME48 W5ME48 PTHR10574:SF406 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA 5 animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000017452.1|UniProtKB=W5NLP8 W5NLP8 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004115.1|UniProtKB=W5M964 W5M964 PTHR12317:SF26 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000008246.1|UniProtKB=W5MNQ3 W5MNQ3 PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006582.1|UniProtKB=W5MHU1 W5MHU1 PTHR11662:SF201 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 2 L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;acidic amino acid transmembrane transporter activity#GO:0015172 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;regulation of synapse structure or activity#GO:0050803;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052;vesicle-mediated transport in synapse#GO:0099003 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 secondary carrier transporter#PC00258;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 LEPOC|Ensembl=ENSLOCG00000000281.1|UniProtKB=W5LW07 W5LW07 PTHR43775:SF37 FATTY ACID SYNTHASE SI:DKEY-61P9.11 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000005108.1|UniProtKB=W5MCP7 W5MCP7 PTHR47979:SF12 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007778.1|UniProtKB=W5MM35 W5MM35 PTHR22526:SF2 ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED regulation of chromosome organization#GO:0033044;regulation of cell communication#GO:0010646;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of chromosome segregation#GO:0051983;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of chromosome separation#GO:1905818;regulation of signaling#GO:0023051;regulation of cell cycle phase transition#GO:1901987;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000017520.1|UniProtKB=W5NLW6 W5NLW6 GJD3 PTHR11984:SF5 CONNEXIN GAP JUNCTION DELTA-3 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000009002.1|UniProtKB=W5MRH4 W5MRH4 ENTPD7 PTHR11782:SF37 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 7 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000005882.1|UniProtKB=W5MFE5 W5MFE5 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009344.1|UniProtKB=W5MSP0 W5MSP0 PTHR23358:SF2 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;DNA modification#GO:0006304;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;DNA demethylation#GO:0080111;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010010.1|UniProtKB=W5MV35 W5MV35 PTHR12999:SF17 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000018228.1|UniProtKB=W5NNX0 W5NNX0 METTL18 PTHR14614:SF39 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018147.1|UniProtKB=W5NNN9 W5NNN9 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000006719.1|UniProtKB=W5MIA4 W5MIA4 PTHR12281:SF6 RP42 RELATED DCN1-LIKE PROTEIN 5 cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008918.1|UniProtKB=W5MR55 W5MR55 PTHR24006:SF915 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE-RELATED cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;cell cycle#GO:0007049;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013085.1|UniProtKB=W5N657 W5N657 PTHR13502:SF7 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CRIB DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005892.1|UniProtKB=W5MFF9 W5MFF9 CCDC148 PTHR21549:SF1 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 148 LEPOC|Ensembl=ENSLOCG00000013126.1|UniProtKB=W5N6A9 W5N6A9 PTHR13019:SF9 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG B cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016970.1|UniProtKB=W5NK19 W5NK19 PTHR24023:SF880 COLLAGEN ALPHA COLLAGEN ALPHA-1(X) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000017357.1|UniProtKB=W5NLF3 W5NLF3 PTHR31410:SF1 TRANSMEMBRANE PROTEIN 246 POST-GPI ATTACHMENT TO PROTEINS FACTOR 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 LEPOC|Ensembl=ENSLOCG00000011838.1|UniProtKB=W5N1Q5 W5N1Q5 CDK18 PTHR24056:SF52 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 18 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006198.1|UniProtKB=W5MGH8 W5MGH8 PTHR23073:SF7 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000008493.1|UniProtKB=W5MPM9 W5MPM9 PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002040.1|UniProtKB=W5M1V6 W5M1V6 PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A-RELATED cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 LEPOC|Ensembl=ENSLOCG00000015161.1|UniProtKB=W5NDF2 W5NDF2 PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000012504.1|UniProtKB=W5N432 W5N432 PTHR24341:SF5 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000010239.1|UniProtKB=W5MVX9 W5MVX9 PTHR16093:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER INNATE IMMUNITY ACTIVATOR PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;cell-cell junction organization#GO:0045216;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein modification process#GO:0031401;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;adherens junction organization#GO:0034332 LEPOC|Ensembl=ENSLOCG00000016906.1|UniProtKB=W5NJU8 W5NJU8 PTHR13140:SF745 MYOSIN UNCONVENTIONAL MYOSIN-VI microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin filament-based movement#GO:0030048;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000012254.1|UniProtKB=W5N370 W5N370 PTHR12824:SF7 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIA SECRETORY PHOSPHOLIPASE A2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase A2 activity#GO:0004623;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004748.1|UniProtKB=W5MBD8 W5MBD8 PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000273.1|UniProtKB=W5LVZ1 W5LVZ1 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011206.1|UniProtKB=W5MZG1 W5MZG1 PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004066.1|UniProtKB=W5M8Z6 W5M8Z6 PTHR22745:SF7 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009123.1|UniProtKB=W5MRW7 W5MRW7 PTHR47958:SF24 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000009020.1|UniProtKB=W5MRI4 W5MRI4 PTHR23291:SF78 BAX INHIBITOR-RELATED FAS APOPTOTIC INHIBITORY MOLECULE 2 ISOFORM X1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011713.1|UniProtKB=W5N188 W5N188 PTHR13342:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045 LEPOC|Ensembl=ENSLOCG00000007703.1|UniProtKB=W5MLU7 W5MLU7 PTHR12442:SF37 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000004682.1|UniProtKB=W5MB58 W5MB58 PTHR10943:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000015021.1|UniProtKB=W5NCY5 W5NCY5 PTHR10279:SF6 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 2 enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;positive regulation of catabolic process#GO:0009896;biological regulation#GO:0065007;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006280.1|UniProtKB=W5MGS6 W5MGS6 PTHR12452:SF0 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008530.1|UniProtKB=W5MPT6 W5MPT6 PTHR43109:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 7 NUCLEOSIDE DIPHOSPHATE KINASE 7 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;axonemal microtubule#GO:0005879 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 LEPOC|Ensembl=ENSLOCG00000017693.1|UniProtKB=W5NMD9 W5NMD9 PTHR33064:SF37 POL PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000014280.1|UniProtKB=W5NAC2 W5NAC2 PTHR15127:SF28 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN F protein binding#GO:0005515;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000000217.1|UniProtKB=W5LVT6 W5LVT6 PTHR44027:SF6 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5B chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009041.1|UniProtKB=W5MRL9 W5MRL9 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002563.1|UniProtKB=W5M3V0 W5M3V0 PTHR11849:SF161 ETS FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000014884.1|UniProtKB=W5NCI0 W5NCI0 PTHR12596:SF2 EXPORTIN 4,7-RELATED EXPORTIN-7 ISOFORM X1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006475.1|UniProtKB=W5MHF9 W5MHF9 PTHR10336:SF84 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000001772.1|UniProtKB=W5M105 W5M105 PTHR23031:SF5 RHOPHILIN RHOPHILIN-2-RELATED negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament bundle assembly#GO:0032231;negative regulation of cellular process#GO:0048523 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016552.1|UniProtKB=W5NII4 W5NII4 PTHR18914:SF30 ALPHA CATENIN VINCULIN_ALPHA-CATENIN FAMILY MEMBER 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;beta-catenin binding#GO:0008013;actin filament binding#GO:0051015 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000001757.1|UniProtKB=W5M0W8 W5M0W8 PTHR24652:SF67 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000145.1|UniProtKB=W5LVK2 W5LVK2 PTHR11062:SF281 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 2 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010310.1|UniProtKB=W5MW74 W5MW74 PTHR11461:SF129 SERINE PROTEASE INHIBITOR, SERPIN SERPIN E3 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000008588.1|UniProtKB=W5MPY1 W5MPY1 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010791.1|UniProtKB=W5MXW3 W5MXW3 PTHR23244:SF465 KELCH REPEAT DOMAIN ZGC:163014 LEPOC|Ensembl=ENSLOCG00000011435.1|UniProtKB=W5N094 W5N094 PTHR35255:SF1 TRANSMEMBRANE PROTEIN 71 TRANSMEMBRANE PROTEIN 71 LEPOC|Ensembl=ENSLOCG00000017518.1|UniProtKB=W5NLW4 W5NLW4 PTHR19290:SF83 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016254.1|UniProtKB=W5NHD6 W5NHD6 PTHR11267:SF20 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX18 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;epithelium development#GO:0060429;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate specification#GO:0001708;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;morphogenesis of an epithelium#GO:0002009;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000015534.1|UniProtKB=W5NER1 W5NER1 DUSP9 PTHR10159:SF388 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 9 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000002025.1|UniProtKB=W5M1T9 W5M1T9 LSM4 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;P-body assembly#GO:0033962;non-membrane-bounded organelle assembly#GO:0140694;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 supramolecular complex#GO:0099080;U6 snRNP#GO:0005688;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014161.1|UniProtKB=W5N9Y5 W5N9Y5 PTHR11937:SF13 ACTIN ACTIN-RELATED PROTEIN 8 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 cytoskeletal protein#PC00085;actin and actin related protein#PC00039;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001753.1|UniProtKB=W5M0W5 W5M0W5 PTHR10498:SF6 PARALEMMIN-RELATED PARALEMMIN-1 LEPOC|Ensembl=ENSLOCG00000010011.1|UniProtKB=W5MV33 W5MV33 COQ2 PTHR11048:SF28 PRENYLTRANSFERASES 4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 acyltransferase#PC00042 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 LEPOC|Ensembl=ENSLOCG00000000381.1|UniProtKB=W5LWB0 W5LWB0 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000017388.1|UniProtKB=W5NLI4 W5NLI4 PTHR22791:SF17 RING-TYPE DOMAIN-CONTAINING PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005670.1|UniProtKB=W5MEP1 W5MEP1 PTHR10278:SF0 CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN peptide hormone binding#GO:0017046;hormone binding#GO:0042562;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of system process#GO:0044057;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;response to endogenous stimulus#GO:0009719;regulation of peptide secretion#GO:0002791;cellular response to hormone stimulus#GO:0032870;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;regulation of hormone secretion#GO:0046883;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of peptide hormone secretion#GO:0090276;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;negative regulation of transport#GO:0051051;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of molecular function#GO:0044092;regulation of peptide transport#GO:0090087 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014693.1|UniProtKB=W5NBT0 W5NBT0 PTHR10827:SF78 RETICULOCALBIN RETICULOCALBIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014346.1|UniProtKB=W5NAK6 W5NAK6 PTHR14207:SF0 STEROL ISOMERASE 3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017389.1|UniProtKB=W5NLI5 W5NLI5 PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000006408.1|UniProtKB=W5MH82 W5MH82 PTHR32215:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015125.1|UniProtKB=W5NDB2 W5NDB2 SLC18A1 PTHR23506:SF31 GH10249P CHROMAFFIN GRANULE AMINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;neurotransmitter transport#GO:0006836;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 secondary carrier transporter#PC00258;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410 LEPOC|Ensembl=ENSLOCG00000009961.1|UniProtKB=W5MUX9 W5MUX9 PTHR23077:SF63 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;proteasomal protein catabolic process#GO:0010498;autophagosome maturation#GO:0097352;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;microtubule-based process#GO:0007017;response to chemical#GO:0042221;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004599.1|UniProtKB=W5MAV1 W5MAV1 PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;RNA polymerase activity#GO:0097747;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;rRNA transcription#GO:0009303;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;transcription elongation by RNA polymerase I#GO:0006362;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 LEPOC|Ensembl=ENSLOCG00000001572.1|UniProtKB=W5M0A3 W5M0A3 PTHR11635:SF126 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-BETA REGULATORY SUBUNIT protein kinase A binding#GO:0051018;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>PKA#P06782;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 LEPOC|Ensembl=ENSLOCG00000007538.1|UniProtKB=W5ML86 W5ML86 PTHR19288:SF94 4-NITROPHENYLPHOSPHATASE-RELATED CHRONOPHIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006362.1|UniProtKB=W5MH17 W5MH17 PTHR46536:SF1 ARL14 EFFECTOR PROTEIN ARL14 EFFECTOR PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002197.1|UniProtKB=W5M2E9 W5M2E9 PTHR12198:SF9 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015441.1|UniProtKB=W5NEE4 W5NEE4 PTHR13254:SF1 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein palmitoylation#GO:0018345;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009508.1|UniProtKB=W5MTA8 W5MTA8 PTHR23235:SF132 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005352.1|UniProtKB=W5MDJ6 W5MDJ6 ACOT12 PTHR11049:SF3 ACYL COENZYME A THIOESTER HYDROLASE ACETYL-COENZYME A THIOESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000015012.1|UniProtKB=W5NCY3 W5NCY3 PTHR11528:SF97 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000001003.1|UniProtKB=W5LYC4 W5LYC4 PTHR12381:SF66 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009368.1|UniProtKB=W5MSR8 W5MSR8 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000013479.1|UniProtKB=W5N7M6 W5N7M6 PTHR48015:SF11 SERINE/THREONINE-PROTEIN KINASE TAO MISSHAPEN-LIKE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016609.1|UniProtKB=W5NIQ9 W5NIQ9 PTHR19336:SF10 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN CEP57L1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000016460.1|UniProtKB=W5NI73 W5NI73 PTHR36688:SF1 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006004.1|UniProtKB=W5MFU7 W5MFU7 PTHR22406:SF2 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 1 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;cytoplasmic microtubule organization#GO:0031122;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;microtubule nucleation#GO:0007020 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003650.1|UniProtKB=W5M7I0 W5M7I0 PTHR11440:SF18 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000006873.1|UniProtKB=W5MIV4 W5MIV4 PTHR43917:SF9 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-1 glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008056.1|UniProtKB=W5MN39 W5MN39 GHR PTHR23036:SF108 CYTOKINE RECEPTOR GROWTH HORMONE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;cytokine receptor activity#GO:0004896;binding#GO:0005488;peptide binding#GO:0042277;cytokine binding#GO:0019955;amide binding#GO:0033218;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;hormone binding#GO:0042562;transmembrane signaling receptor activity#GO:0004888 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to hormone#GO:0009725;response to chemical#GO:0042221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010273.1|UniProtKB=W5MW32 W5MW32 PTHR13723:SF33 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 9 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015602.1|UniProtKB=W5NF02 W5NF02 PTHR10615:SF26 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6A histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;N-acyltransferase activity#GO:0016410;molecular adaptor activity#GO:0060090;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000005086.1|UniProtKB=W5MCL5 W5MCL5 PTHR46272:SF4 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016570.1|UniProtKB=W5NIK9 W5NIK9 PTHR34031:SF1 CENTROSOMAL PROTEIN OF 162 KDA CENTROSOMAL PROTEIN OF 162 KDA organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 supramolecular complex#GO:0099080;axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;axonemal microtubule#GO:0005879 LEPOC|Ensembl=ENSLOCG00000005927.1|UniProtKB=W5MFJ7 W5MFJ7 PKP4 PTHR10372:SF8 PLAKOPHILLIN-RELATED PLAKOPHILIN-4 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000017921.1|UniProtKB=W5NN15 W5NN15 KCNA3 PTHR11537:SF28 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014937.1|UniProtKB=W5NCN3 W5NCN3 PTHR24072:SF137 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002453.1|UniProtKB=W5M3D3 W5M3D3 PTHR13025:SF7 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN FAMILY, MEMBER D2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014172.1|UniProtKB=W5NA17 W5NA17 PTHR10166:SF25 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000000024.1|UniProtKB=W5LV71 W5LV71 PTHR43544:SF12 SHORT-CHAIN DEHYDROGENASE/REDUCTASE NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000366.1|UniProtKB=W5LW93 W5LW93 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016634.1|UniProtKB=W5NIT8 W5NIT8 PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003028.1|UniProtKB=W5M5A9 W5M5A9 PTHR45767:SF5 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005792.1|UniProtKB=W5MF34 W5MF34 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000010900.1|UniProtKB=W5MYA5 W5MYA5 PTHR13948:SF37 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 6 ISOFORM X1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017267.1|UniProtKB=W5NL50 W5NL50 PTHR11845:SF13 5'-DEOXYNUCLEOTIDASE HDDC2 5'-DEOXYNUCLEOTIDASE HDDC2 LEPOC|Ensembl=ENSLOCG00000013267.1|UniProtKB=W5N6U4 W5N6U4 PTHR15874:SF1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cell division#GO:0051301;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;chromosome condensation#GO:0030261;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;spindle localization#GO:0051653;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic chromosome condensation#GO:0007076;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000005052.1|UniProtKB=W5MCH0 W5MCH0 PTHR36129:SF2 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED RICIN B LECTIN DOMAIN-CONTAINING PROTEIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005228.1|UniProtKB=W5MD35 W5MD35 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015969.1|UniProtKB=W5NGA5 W5NGA5 PTHR31503:SF10 VACUOLAR CALCIUM ION TRANSPORTER VNX1 PROTEIN calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012223.1|UniProtKB=W5N328 W5N328 CDIN1 PTHR31661:SF1 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 LEPOC|Ensembl=ENSLOCG00000000950.1|UniProtKB=W5LY54 W5LY54 PTHR19375:SF169 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 13 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000017288.1|UniProtKB=W5NL77 W5NL77 PTHR24249:SF415 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 1 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004178.1|UniProtKB=W5M9G4 W5M9G4 PTHR43108:SF1 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;kidney development#GO:0001822;positive regulation of Wnt signaling pathway#GO:0030177;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;external encapsulating structure organization#GO:0045229;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of cytokine production#GO:0001819;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;regulation of cytokine production#GO:0001817;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cell surface#GO:0009986;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012021.1|UniProtKB=W5N2C5 W5N2C5 PTHR24246:SF52 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004077.1|UniProtKB=W5M909 W5M909 PTHR45752:SF146 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 18 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016606.1|UniProtKB=W5NIQ1 W5NIQ1 PTHR21356:SF1 ARMADILLO REPEAT CONTAINING 2 ARMADILLO REPEAT-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 LEPOC|Ensembl=ENSLOCG00000014184.1|UniProtKB=W5NA13 W5NA13 PTHR43157:SF32 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 12 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008878.1|UniProtKB=W5MR00 W5MR00 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000007858.1|UniProtKB=W5MMD0 W5MMD0 PTHR21041:SF17 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE DCST1 LEPOC|Ensembl=ENSLOCG00000001167.1|UniProtKB=W5LYX2 W5LYX2 PTHR11590:SF6 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010156.1|UniProtKB=W5MVM7 W5MVM7 PTHR12406:SF7 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;triglyceride catabolic process#GO:0019433;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000003522.1|UniProtKB=W5M755 W5M755 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009741.1|UniProtKB=W5MU44 W5MU44 PTHR12393:SF6 SPHINGOMYELIN PHOSPHODIESTERASE RELATED SPHINGOMYELIN PHOSPHODIESTERASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016532.1|UniProtKB=W5NIF9 W5NIF9 PTHR42881:SF3 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003828.1|UniProtKB=W5M870 W5M870 PTHR45954:SF2 LD33695P G-PROTEIN-SIGNALING MODULATOR 1 nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;binding#GO:0005488;molecular function regulator activity#GO:0098772 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 LEPOC|Ensembl=ENSLOCG00000011297.1|UniProtKB=W5MZS6 W5MZS6 PTHR11949:SF9 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000018168.1|UniProtKB=W5NNR0 W5NNR0 PTHR24225:SF68 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014082.1|UniProtKB=W5N9P3 W5N9P3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015622.1|UniProtKB=W5NF24 W5NF24 PTHR16133:SF4 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC TRANSPORTER ZIP9 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006079.1|UniProtKB=W5MG36 W5MG36 PTHR18945:SF34 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT DELTA signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013601.1|UniProtKB=W5N812 W5N812 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000014505.1|UniProtKB=W5NB45 W5NB45 PTHR48112:SF32 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000014864.1|UniProtKB=W5NCE6 W5NCE6 PTHR34490:SF1 PROTEIN CBG12054-RELATED GALAXIN-LIKE LEPOC|Ensembl=ENSLOCG00000017493.1|UniProtKB=W5NLT9 W5NLT9 PTHR10270:SF111 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-3 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;head development#GO:0060322;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000007424.1|UniProtKB=W5MKV4 W5MKV4 PTHR12845:SF6 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19 regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of organelle organization#GO:0033043;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of hydrolase activity#GO:0051336;regulation of actin filament-based process#GO:0032970 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005428.1|UniProtKB=W5MDV7 W5MDV7 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016672.1|UniProtKB=W5NIY7 W5NIY7 PTHR46517:SF1 FRUCTOSE-2,6-BISPHOSPHATASE TIGAR FRUCTOSE-2,6-BISPHOSPHATASE TIGAR hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of amide metabolic process#GO:0034248;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881 LEPOC|Ensembl=ENSLOCG00000011816.1|UniProtKB=W5N1M2 W5N1M2 PTHR23314:SF0 SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING SPERM-ASSOCIATED ANTIGEN 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017;cilium movement#GO:0003341 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000821.1|UniProtKB=W5LXR2 W5LXR2 PTHR11935:SF116 BETA LACTAMASE DOMAIN HYDROLASE PNKD-RELATED LEPOC|Ensembl=ENSLOCG00000011919.1|UniProtKB=W5N1Z4 W5N1Z4 C7orf25 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 LEPOC|Ensembl=ENSLOCG00000013340.1|UniProtKB=W5N736 W5N736 PTHR16207:SF1 SET DOMAIN-CONTAINING PROTEIN PROTEIN TASOR protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of cellular component biogenesis#GO:0044087;regulation of chromatin organization#GO:1902275;protein localization to organelle#GO:0033365;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;negative regulation of biosynthetic process#GO:0009890;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular macromolecule localization#GO:0070727;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000016635.1|UniProtKB=W5NIT9 W5NIT9 PTHR34174:SF1 HYDROLETHALUS SYNDROME PROTEIN 1 CENTRIOLAR AND CILIOGENESIS-ASSOCIATED PROTEIN HYLS1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002726.1|UniProtKB=W5M494 W5M494 PTHR24399:SF19 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 20 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016310.1|UniProtKB=W5NHM5 W5NHM5 PTHR10623:SF10 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;non-membrane-bounded organelle assembly#GO:0140694;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012138.1|UniProtKB=W5N2S2 W5N2S2 MYOCD PTHR22793:SF11 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;striated muscle tissue development#GO:0014706;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;muscle tissue development#GO:0060537;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003222.1|UniProtKB=W5M5Z8 W5M5Z8 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006665.1|UniProtKB=W5MI44 W5MI44 PGM1 PTHR22573:SF60 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000011186.1|UniProtKB=W5MZD9 W5MZD9 PTHR12207:SF3 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN PROSTAGLANDIN F2 RECEPTOR NEGATIVE REGULATOR cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016376.1|UniProtKB=W5NHW9 W5NHW9 PTHR11757:SF19 PROTEASE FAMILY S9A OLIGOPEPTIDASE PROLYL ENDOPEPTIDASE-LIKE serine protease#PC00203;protease#PC00190 Vasopressin synthesis#P04395>Endo Peptidase#P04596 LEPOC|Ensembl=ENSLOCG00000016586.1|UniProtKB=W5NIM6 W5NIM6 PTHR28665:SF1 BEN DOMAIN-CONTAINING PROTEIN 3 BEN DOMAIN-CONTAINING PROTEIN 3 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000017028.1|UniProtKB=W5NK86 W5NK86 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010535.1|UniProtKB=W5MWZ7 W5MWZ7 PTHR47978:SF26 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;regulation of transport#GO:0051049;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;autophagy#GO:0006914;regulation of exocytosis#GO:0017157;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015589.1|UniProtKB=W5NEY4 W5NEY4 PTHR24215:SF31 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE RICH PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006818.1|UniProtKB=W5MIQ1 W5MIQ1 PTHR24082:SF112 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001514.1|UniProtKB=W5M040 W5M040 PTHR11229:SF8 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009524.1|UniProtKB=W5MTD3 W5MTD3 PTHR11309:SF75 FRIZZLED FRIZZLED-6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000011998.1|UniProtKB=W5N294 W5N294 PTHR10489:SF664 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 9 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000009246.1|UniProtKB=W5MSC6 W5MSC6 SLC46A3 PTHR23507:SF32 ZGC:174356 SI:DKEY-5G14.1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000379.1|UniProtKB=W5LWA5 W5LWA5 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004741.1|UniProtKB=W5MBC7 W5MBC7 CMKLR1 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000010522.1|UniProtKB=W5MWY6 W5MWY6 PTHR13202:SF0 MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal peptide processing#GO:0006465 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 protease#PC00190;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Signal Peptidase#P04589 LEPOC|Ensembl=ENSLOCG00000007241.1|UniProtKB=W5MK57 W5MK57 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016512.1|UniProtKB=W5NIE0 W5NIE0 PTHR15952:SF11 EXPORTIN-T/LOS1 EXPORTIN-T tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;nuclear pore#GO:0005643;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear periphery#GO:0034399;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006809.1|UniProtKB=W5MIL2 W5MIL2 PTHR13964:SF37 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006472.1|UniProtKB=W5MHF6 W5MHF6 TRIM9 PTHR25462:SF306 BONUS, ISOFORM C-RELATED TRIPARTITE MOTIF CONTAINING 9 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009115.1|UniProtKB=W5MRW1 W5MRW1 PTHR10353:SF38 GLYCOSYL HYDROLASE LACTASE_PHLORIZIN HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017317.1|UniProtKB=W5NLB3 W5NLB3 PTHR13147:SF5 FOUR-JOINTED BOX PROTEIN 1 FOUR-JOINTED BOX PROTEIN 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000009164.1|UniProtKB=W5MS18 W5MS18 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-6 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000008226.1|UniProtKB=W5MNM9 W5MNM9 PTHR43243:SF4 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001103.1|UniProtKB=W5LYP2 W5LYP2 PTHR13723:SF26 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 10 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000104.1|UniProtKB=W5LVF6 W5LVF6 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008901.1|UniProtKB=W5MR27 W5MR27 PTHR45997:SF1 DNA LIGASE 4 DNA LIGASE 4 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013983.1|UniProtKB=W5N9C7 W5N9C7 PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014940.1|UniProtKB=W5NCP1 W5NCP1 PTHR14167:SF54 SH3 DOMAIN-CONTAINING VINEXIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002872.1|UniProtKB=W5M4R5 W5M4R5 PTHR22426:SF1 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 LYSINE-RICH NUCLEOLAR PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017796.1|UniProtKB=W5NMP1 W5NMP1 GPR45 PTHR24245:SF4 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 45-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000012364.1|UniProtKB=W5N3N7 W5N3N7 PTHR45746:SF2 LP21163P REGULATOR OF G-PROTEIN SIGNALING 6 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000012236.1|UniProtKB=W5N342 W5N342 PTHR43908:SF4 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 14 heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;chaperone cofactor-dependent protein refolding#GO:0051085;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017287.1|UniProtKB=W5NL76 W5NL76 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006369.1|UniProtKB=W5MH44 W5MH44 PTHR10574:SF240 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-3 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000008273.1|UniProtKB=W5MNV0 W5MNV0 PTHR10353:SF10 GLYCOSYL HYDROLASE KLOTHO glucosidase activity#GO:0015926;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;growth factor receptor binding#GO:0070851;fibroblast growth factor binding#GO:0017134;growth factor binding#GO:0019838;protein binding#GO:0005515;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 fibroblast growth factor receptor signaling pathway#GO:0008543;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular response to fibroblast growth factor stimulus#GO:0044344;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018292.1|UniProtKB=W5NP34 W5NP34 PTHR11636:SF75 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010153.1|UniProtKB=W5MVM2 W5MVM2 PTHR17611:SF3 DNA SEGMENT, CHR 5, ERATO DOI 579, EXPRESSED DNA SEGMENT, CHR 5, ERATO DOI 579, EXPRESSED LEPOC|Ensembl=ENSLOCG00000001200.1|UniProtKB=W5LYZ6 W5LYZ6 PTHR13848:SF3 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012727.1|UniProtKB=W5N4W4 W5N4W4 PTHR22730:SF4 PROMININ PROM PROTEIN PROMININ-1-A-LIKE small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 microvillus#GO:0005902;extracellular region#GO:0005576;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;cell surface#GO:0009986;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014124.1|UniProtKB=W5N9T9 W5N9T9 PTHR28585:SF1 TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES LEPOC|Ensembl=ENSLOCG00000015529.1|UniProtKB=W5NEQ4 W5NEQ4 PTHR24393:SF165 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 555-LIKE DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015393.1|UniProtKB=W5NE81 W5NE81 PTHR13710:SF105 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;DNA geometric change#GO:0032392;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;DNA duplex unwinding#GO:0032508;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015763.1|UniProtKB=W5NFJ8 W5NFJ8 PTHR23113:SF168 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 PI3 kinase pathway#P00048>SOS#P01185;T cell activation#P00053>SOS#P01307;Angiogenesis#P00005>SOS-1#P00193;Integrin signalling pathway#P00034>SOS#P00920;PDGF signaling pathway#P00047>SOS#P01159;B cell activation#P00010>SOS#P00379;Ras Pathway#P04393>SOS#P04552;Interleukin signaling pathway#P00036>SOS#P00981;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Sos#P00850;CCKR signaling map#P06959>SOS1#P07061;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;FGF signaling pathway#P00021>SOS#P00641;EGF receptor signaling pathway#P00018>SOS#P00558;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883 LEPOC|Ensembl=ENSLOCG00000006468.1|UniProtKB=W5MHF4 W5MHF4 PTHR23235:SF111 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 16 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016245.1|UniProtKB=W5NHC2 W5NHC2 TMEM19 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008784.1|UniProtKB=W5MQP0 W5MQP0 PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003182.1|UniProtKB=W5M5V5 W5M5V5 PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;microtubule organizing center#GO:0005815;intraciliary transport particle A#GO:0030991;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012942.1|UniProtKB=W5N5N6 W5N5N6 PTHR23255:SF62 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000003943.1|UniProtKB=W5M8J9 W5M8J9 PTHR20921:SF0 TRANSMEMBRANE PROTEIN 222 TRANSMEMBRANE PROTEIN 222 LEPOC|Ensembl=ENSLOCG00000011041.1|UniProtKB=W5MYU5 W5MYU5 PTHR22984:SF32 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001165.1|UniProtKB=W5LYV8 W5LYV8 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002463.1|UniProtKB=W5M3D9 W5M3D9 PTHR43544:SF7 SHORT-CHAIN DEHYDROGENASE/REDUCTASE NADB-LER2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009312.1|UniProtKB=W5MSJ9 W5MSJ9 PTHR15919:SF12 DAPPER-RELATED DAPPER HOMOLOG 1 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>Frodo#P01470;Wnt signaling pathway#P00057>Dapper#P01469 LEPOC|Ensembl=ENSLOCG00000005715.1|UniProtKB=W5MET6 W5MET6 PTHR33560:SF1 PROTEIN FAM227B PROTEIN FAM227A LEPOC|Ensembl=ENSLOCG00000000531.1|UniProtKB=W5LWT0 W5LWT0 PTHR25952:SF256 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN EXODEOXYRIBONUCLEASE III LEPOC|Ensembl=ENSLOCG00000003735.1|UniProtKB=W5M7T1 W5M7T1 PSMA7 PTHR11599:SF40 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000010012.1|UniProtKB=W5MV30 W5MV30 PTHR24412:SF462 KELCH PROTEIN KELCH-LIKE PROTEIN 38 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006379.1|UniProtKB=W5MH41 W5MH41 PTHR45771:SF9 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-C4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012305.1|UniProtKB=W5N3D0 W5N3D0 PTHR46144:SF5 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER PROTEIN 346 LEPOC|Ensembl=ENSLOCG00000015736.1|UniProtKB=W5NFG0 W5NFG0 PTHR10331:SF28 T COMPLEX PROTEIN 10 CENTROMERE PROTEIN J-LIKE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;centriole assembly#GO:0098534;cell projection organization#GO:0030030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;centriole elongation#GO:0061511;plasma membrane bounded cell projection assembly#GO:0120031;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006182.1|UniProtKB=W5MGG2 W5MGG2 PTHR12606:SF30 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 1 hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016192.1|UniProtKB=W5NH50 W5NH50 PTHR47573:SF1 PROTEIN AF-9 HOMOLOG PROTEIN AF-9 HOMOLOG LEPOC|Ensembl=ENSLOCG00000010189.1|UniProtKB=W5MVS2 W5MVS2 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005754.1|UniProtKB=W5MEY6 W5MEY6 PTHR23415:SF30 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;ubiquitin-like protein binding#GO:0032182;protein serine/threonine kinase activator activity#GO:0043539;ubiquitin binding#GO:0043130;protein binding#GO:0005515;protein kinase binding#GO:0019901 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cellular process#GO:0050794 SCF ubiquitin ligase complex#GO:0019005;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002865.1|UniProtKB=W5M4R6 W5M4R6 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248 oxidase#PC00175;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000003860.1|UniProtKB=W5M899 W5M899 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML54 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010551.1|UniProtKB=W5MX23 W5MX23 PTHR13396:SF3 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;transport#GO:0006810;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;monoatomic cation transport#GO:0006812;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;metal ion transport#GO:0030001;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;monoatomic ion transport#GO:0006811;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008344.1|UniProtKB=W5MP27 W5MP27 PTHR18945:SF571 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013035.1|UniProtKB=W5N605 W5N605 PTHR14920:SF0 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT DOMAIN 19 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000010345.1|UniProtKB=W5MWC1 W5MWC1 PTHR16056:SF16 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle microtubule#GO:0005876;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000006904.1|UniProtKB=W5MJ24 W5MJ24 PTHR14491:SF9 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHB-LIKE LEPOC|Ensembl=ENSLOCG00000011928.1|UniProtKB=W5N206 W5N206 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000000626.1|UniProtKB=W5LX35 W5LX35 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000749.1|UniProtKB=W5LXH5 W5LXH5 PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol transporter activity#GO:0015248;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001720.1|UniProtKB=W5M0S9 W5M0S9 PTHR46756:SF21 TRANSGELIN GAS2-LIKE PROTEIN 2 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;tubulin binding#GO:0015631;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;protein localization to cytoskeleton#GO:0044380;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011416.1|UniProtKB=W5N074 W5N074 PTHR10250:SF4 MICROSOMAL GLUTATHIONE S-TRANSFERASE LEUKOTRIENE C4 SYNTHASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 LEPOC|Ensembl=ENSLOCG00000017609.1|UniProtKB=W5NM55 W5NM55 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING BLOODY FINGERS-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001571.1|UniProtKB=W5M087 W5M087 SH3BGR PTHR12232:SF1 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002932.1|UniProtKB=W5M4Z6 W5M4Z6 PTHR24061:SF579 CALCIUM-SENSING RECEPTOR-RELATED OLFACTORY RECEPTOR C FAMILY, U1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012978.1|UniProtKB=W5N5S2 W5N5S2 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011989.1|UniProtKB=W5N289 W5N289 PTHR43272:SF80 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG2 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017821.1|UniProtKB=W5NMR5 W5NMR5 PTHR26451:SF887 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN SI:DKEYP-3F10.17 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001371.1|UniProtKB=W5LZK1 W5LZK1 PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000007364.1|UniProtKB=W5MKL8 W5MKL8 PTHR48016:SF31 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 8 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>TPL2#P01364;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 LEPOC|Ensembl=ENSLOCG00000011880.1|UniProtKB=W5N1V3 W5N1V3 PTHR14885:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000010343.1|UniProtKB=W5MWB5 W5MWB5 PTHR23166:SF9 FILAMIN/GPBP-INTERACTING PROTEIN CTTNBP2 N-TERMINAL-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000008033.1|UniProtKB=W5MMZ4 W5MMZ4 PTHR36128:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 LEPOC|Ensembl=ENSLOCG00000009023.1|UniProtKB=W5MRK0 W5MRK0 PTHR24278:SF25 COAGULATION FACTOR COAGULATION FACTOR IX extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012631.1|UniProtKB=W5N4I6 W5N4I6 IP6K3 PTHR12400:SF73 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000001836.1|UniProtKB=W5M1E0 W5M1E0 PTHR45861:SF1 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;DNA-directed DNA polymerase activity#GO:0003887;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;mitotic cell cycle#GO:0000278;nucleic acid metabolic process#GO:0090304;mitotic DNA replication initiation#GO:1902975;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic DNA replication#GO:1902969;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nuclear replication fork#GO:0043596;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 DNA replication#P00017>Pol alpha#P00531 LEPOC|Ensembl=ENSLOCG00000008676.1|UniProtKB=W5MQ91 W5MQ91 PTHR23504:SF14 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 9 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009763.1|UniProtKB=W5MU71 W5MU71 PTHR10681:SF128 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular homeostasis#GO:0019725;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017164.1|UniProtKB=W5NKQ7 W5NKQ7 PTHR19282:SF377 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014732.1|UniProtKB=W5NBX8 W5NBX8 PTHR46520:SF1 SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;regulation of lipid metabolic process#GO:0019216;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009190.1|UniProtKB=W5MS56 W5MS56 PTHR13500:SF0 NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of LSU-rRNA#GO:0000470 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015575.1|UniProtKB=W5NEX0 W5NEX0 ANKRD26 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 LEPOC|Ensembl=ENSLOCG00000002268.1|UniProtKB=W5M2N7 W5M2N7 PTHR19424:SF0 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR BINDING PROTEIN 1 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001421.1|UniProtKB=W5LZR5 W5LZR5 PTHR13589:SF14 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 1 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>TORC1#P06788 LEPOC|Ensembl=ENSLOCG00000006272.1|UniProtKB=W5MGR3 W5MGR3 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001172.1|UniProtKB=W5LYX6 W5LYX6 PTHR24349:SF254 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p38 MAPK pathway#P05918>MNK2#P06017;Oxidative stress response#P00046>MNK1/2#P01137;Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149 LEPOC|Ensembl=ENSLOCG00000010810.1|UniProtKB=W5MXY8 W5MXY8 PTHR10605:SF55 HEPARAN SULFATE SULFOTRANSFERASE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016921.1|UniProtKB=W5NJV9 W5NJV9 PTHR15507:SF14 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 292 nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004433.1|UniProtKB=W5MA87 W5MA87 PTHR23166:SF7 FILAMIN/GPBP-INTERACTING PROTEIN LEUCINE ZIPPER PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010937.1|UniProtKB=W5MYG0 W5MYG0 PTHR10010:SF21 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2A secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;transport#GO:0006810;homeostatic process#GO:0042592;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;inorganic anion transport#GO:0015698 brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015236.1|UniProtKB=W5NDP0 W5NDP0 PTHR19970:SF0 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003408.1|UniProtKB=W5M6M5 W5M6M5 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000009345.1|UniProtKB=W5MSP1 W5MSP1 PTHR13172:SF5 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016012.1|UniProtKB=W5NGG9 W5NGG9 PTHR13018:SF24 PROBABLE MEMBRANE PROTEIN DUF221-RELATED CSC1-LIKE PROTEIN 1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006138.1|UniProtKB=W5MGB1 W5MGB1 PTHR45618:SF1 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED DICARBOXYLATE CARRIER SLC25A8 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to stress#GO:0006950;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005199.1|UniProtKB=W5MCZ9 W5MCZ9 PTHR24207:SF0 ZYX102 PROTEIN LIPOMA-PREFERRED PARTNER cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 actomyosin#GO:0042641;intracellular non-membrane-bounded organelle#GO:0043232;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000007168.1|UniProtKB=W5MJW3 W5MJW3 PTHR22761:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4B endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013414.1|UniProtKB=W5N7D0 W5N7D0 ENDOV PTHR28511:SF1 ENDONUCLEASE V ENDONUCLEASE V catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 LEPOC|Ensembl=ENSLOCG00000010636.1|UniProtKB=W5MXC3 W5MXC3 PTHR11685:SF463 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING ANKYRIN REPEAT AND IBR DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018278.1|UniProtKB=W5NP20 W5NP20 PTHR20855:SF41 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;response to steroid hormone#GO:0048545 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013196.1|UniProtKB=W5N6J7 W5N6J7 PTHR10921:SF0 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;establishment or maintenance of cell polarity#GO:0007163;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;transport#GO:0006810;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component assembly#GO:0022607;establishment of chromosome localization#GO:0051303;vesicle localization#GO:0051648;cell motility#GO:0048870;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;establishment of spindle localization#GO:0051293;transport along microtubule#GO:0010970;regulation of neuron projection development#GO:0010975;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;centrosome localization#GO:0051642;protein polymerization#GO:0051258;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;chromosome localization#GO:0050000;cell migration#GO:0016477;microtubule nucleation#GO:0007020;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000002432.1|UniProtKB=W5M397 W5M397 PTHR25465:SF30 B-BOX DOMAIN CONTAINING FINTRIM FAMILY, MEMBER 82 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012973.1|UniProtKB=W5N5R9 W5N5R9 N4BP2 PTHR46535:SF1 NEDD4-BINDING PROTEIN 2 NEDD4-BINDING PROTEIN 2 endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016953.1|UniProtKB=W5NJZ8 W5NJZ8 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Interleukin signaling pathway#P00036>MEK#P00984;p38 MAPK pathway#P05918>TAK1#P06037;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Toll receptor signaling pathway#P00054>TAK1#P01370;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;TGF-beta signaling pathway#P00052>TAK#P01285 LEPOC|Ensembl=ENSLOCG00000015715.1|UniProtKB=W5NFD7 W5NFD7 PTHR21661:SF78 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;organic cyclic compound metabolic process#GO:1901360;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002005.1|UniProtKB=W5M1R6 W5M1R6 PTHR23024:SF222 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE deacetylase#PC00087;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011354.1|UniProtKB=W5MZZ5 W5MZZ5 PTHR23235:SF56 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 12 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002756.1|UniProtKB=W5M4D3 W5M4D3 PTHR37557:SF4 115 KDA PROTEIN IN TYPE-1 RETROTRANSPOSABLE ELEMENT R1DM-LIKE PROTEIN-RELATED-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012594.1|UniProtKB=W5N4E3 W5N4E3 PTHR13419:SF1 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 4 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012998.1|UniProtKB=W5N5V8 W5N5V8 PTHR43107:SF4 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 2 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;import into cell#GO:0098657;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003542.1|UniProtKB=W5M751 W5M751 PTHR11610:SF3 LIPASE LIPOPROTEIN LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;triglyceride lipase activity#GO:0004806 regulation of biological process#GO:0050789;lipid metabolic process#GO:0006629;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 2-arachidonoylglycerol biosynthesis#P05726>DGL#P05736 LEPOC|Ensembl=ENSLOCG00000012542.1|UniProtKB=W5N488 W5N488 NPB PTHR28553:SF1 NEUROPEPTIDE B NEUROPEPTIDE B protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;behavior#GO:0007610;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;feeding behavior#GO:0007631;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000018200.1|UniProtKB=W5NNU2 W5NNU2 PTHR36684:SF1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX14 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX14 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001046.1|UniProtKB=W5LYG5 W5LYG5 PTHR16120:SF0 AP-5 COMPLEX SUBUNIT SIGMA-1 AP-5 COMPLEX SUBUNIT SIGMA-1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000015187.1|UniProtKB=W5NDH8 W5NDH8 PTHR22811:SF38 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;positive regulation of signal transduction#GO:0009967;transport#GO:0006810;regulation of signaling#GO:0023051;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;regulation of intracellular signal transduction#GO:1902531;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;organic substance transport#GO:0071702;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cell communication#GO:0010646;Golgi organization#GO:0007030;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000001035.1|UniProtKB=W5LYE9 W5LYE9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012742.1|UniProtKB=W5N4X4 W5N4X4 PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007474.1|UniProtKB=W5ML19 W5ML19 PTHR21494:SF0 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 LEPOC|Ensembl=ENSLOCG00000001690.1|UniProtKB=W5M0P2 W5M0P2 PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED germ cell development#GO:0007281;cellular developmental process#GO:0048869;cell division#GO:0051301;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;cellular process#GO:0009987;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 LEPOC|Ensembl=ENSLOCG00000004517.1|UniProtKB=W5MAJ9 W5MAJ9 PTHR23086:SF26 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000013163.1|UniProtKB=W5N6F8 W5N6F8 PTHR23348:SF42 PERIAXIN/AHNAK PERIAXIN neurogenesis#GO:0022008;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;plasma membrane organization#GO:0007009;developmental process#GO:0032502;endomembrane system organization#GO:0010256;gliogenesis#GO:0042063;peripheral nervous system development#GO:0007422;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;myelination#GO:0042552 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006479.1|UniProtKB=W5MHH1 W5MHH1 PTHR10631:SF3 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016852.1|UniProtKB=W5NJM5 W5NJM5 PTHR46001:SF5 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM2 LEPOC|Ensembl=ENSLOCG00000016698.1|UniProtKB=W5NJ21 W5NJ21 PTHR12198:SF10 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX 1A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013964.1|UniProtKB=W5N9C0 W5N9C0 PTHR22903:SF4 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 1 LEPOC|Ensembl=ENSLOCG00000009405.1|UniProtKB=W5MSW5 W5MSW5 PTHR24306:SF0 FAMILY NOT NAMED 7-ALPHA-HYDROXYCHOLEST-4-EN-3-ONE 12-ALPHA-HYDROXYLASE steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 LEPOC|Ensembl=ENSLOCG00000013823.1|UniProtKB=W5N8U2 W5N8U2 SLC2A4 PTHR23503:SF120 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 4 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002367.1|UniProtKB=W5M317 W5M317 PTHR28605:SF1 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 LEPOC|Ensembl=ENSLOCG00000009432.1|UniProtKB=W5MT02 W5MT02 PTHR24255:SF13 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016835.1|UniProtKB=W5NJJ9 W5NJJ9 PTHR11037:SF16 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 1 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012894.1|UniProtKB=W5N5H1 W5N5H1 PTHR31017:SF1 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014994.1|UniProtKB=W5NCV4 W5NCV4 PTHR33768:SF6 MIP11318P SI:CH211-284K5.2 LEPOC|Ensembl=ENSLOCG00000011363.1|UniProtKB=W5N016 W5N016 PTHR10663:SF315 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN 4-RELATED guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002258.1|UniProtKB=W5M2M9 W5M2M9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005716.1|UniProtKB=W5MEU5 W5MEU5 PTHR11412:SF139 MACROGLOBULIN / COMPLEMENT C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 8 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000010210.1|UniProtKB=W5MVU1 W5MVU1 PTHR12369:SF19 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006199.1|UniProtKB=W5MGI2 W5MGI2 PTHR11958:SF22 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 LEPOC|Ensembl=ENSLOCG00000004735.1|UniProtKB=W5MBC6 W5MBC6 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000001229.1|UniProtKB=W5LZ34 W5LZ34 PTHR47231:SF1 UPF0722 PROTEIN C11ORF88 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN HOATZ LEPOC|Ensembl=ENSLOCG00000003067.1|UniProtKB=W5M5H4 W5M5H4 PTHR10066:SF67 BETA-GLUCURONIDASE BETA-GLUCURONIDASE carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;glycosyl compound metabolic process#GO:1901657;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000000789.1|UniProtKB=W5LXM0 W5LXM0 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 LEPOC|Ensembl=ENSLOCG00000002768.1|UniProtKB=W5M4E8 W5M4E8 URM1 PTHR14986:SF4 RURM1 PROTEIN UBIQUITIN-RELATED MODIFIER 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009249.1|UniProtKB=W5MSD9 W5MSD9 PTHR46022:SF5 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Hedgehog signaling pathway#P00025>Patched#P00689 LEPOC|Ensembl=ENSLOCG00000001096.1|UniProtKB=W5LYQ6 W5LYQ6 PTHR24255:SF28 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED ST14 TRANSMEMBRANE SERINE PROTEASE MATRIPTASE B hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008388.1|UniProtKB=W5MP80 W5MP80 PTHR45622:SF60 UBIQUITIN-PROTEIN LIGASE E3A-RELATED UBIQUITIN-PROTEIN LIGASE E3A transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000008720.1|UniProtKB=W5MQG5 W5MQG5 PTHR10165:SF90 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011417.1|UniProtKB=W5N081 W5N081 PTHR11455:SF10 CRYPTOCHROME CRYPTOCHROME 2B-RELATED nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deoxyribodipyrimidine photo-lyase activity#GO:0003904;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501 LEPOC|Ensembl=ENSLOCG00000009302.1|UniProtKB=W5MSJ0 W5MSJ0 PTHR12002:SF15 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000011892.1|UniProtKB=W5N1W7 W5N1W7 PTHR14677:SF37 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001573.1|UniProtKB=W5M090 W5M090 PTHR24072:SF24 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 LEPOC|Ensembl=ENSLOCG00000005883.1|UniProtKB=W5MFE7 W5MFE7 PTHR10454:SF13 CASPASE CASPASE-4 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of response to external stimulus#GO:0032101;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;positive regulation of response to external stimulus#GO:0032103;regulation of response to stress#GO:0080134;programmed cell death#GO:0012501;positive regulation of inflammatory response#GO:0050729;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of defense response#GO:0031349;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004985.1|UniProtKB=W5MC95 W5MC95 PTHR11686:SF19 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 5 PROENZYME hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound catabolic process#GO:1901565;peptide catabolic process#GO:0043171;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glutathione metabolic process#GO:0006749;inflammatory response#GO:0006954;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;defense response#GO:0006952;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;response to stimulus#GO:0050896;sulfur compound catabolic process#GO:0044273;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008167.1|UniProtKB=W5MNE9 W5MNE9 PTHR35287:SF1 SI:ZFOS-911D5.4 SI:ZFOS-911D5.4 LEPOC|Ensembl=ENSLOCG00000010751.1|UniProtKB=W5MXR1 W5MXR1 PTHR16134:SF2 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 21-RELATED regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;response to radiation#GO:0009314;biological regulation#GO:0065007;response to abiotic stimulus#GO:0009628;regulation of circadian rhythm#GO:0042752 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003131.1|UniProtKB=W5M5M8 W5M5M8 PTHR46987:SF4 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-2 LEPOC|Ensembl=ENSLOCG00000007349.1|UniProtKB=W5MKK0 W5MKK0 PTHR12994:SF18 SECERNIN SECERNIN-3 LEPOC|Ensembl=ENSLOCG00000016719.1|UniProtKB=W5NJ48 W5NJ48 PTHR28664:SF3 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000015698.1|UniProtKB=W5NFB8 W5NFB8 UPF2 PTHR12839:SF7 NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2 REGULATOR OF NONSENSE TRANSCRIPTS 2 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004217.1|UniProtKB=W5M9I3 W5M9I3 PTHR11866:SF32 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E RECEPTOR 4 (SUBTYPE EP4) C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cytosolic calcium ion concentration#GO:0007204;response to lipid#GO:0033993;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;defense response#GO:0006952;signaling#GO:0023052;response to organic substance#GO:0010033;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of response to stress#GO:0080134;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005848.1|UniProtKB=W5MFA1 W5MFA1 ACVR1C PTHR23255:SF58 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000017137.1|UniProtKB=W5NKM0 W5NKM0 PTHR25465:SF14 B-BOX DOMAIN CONTAINING E3 UBIQUITIN-PROTEIN LIGASE TRIM65 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016247.1|UniProtKB=W5NHC7 W5NHC7 PTHR22957:SF300 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 15 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000006662.1|UniProtKB=W5MI37 W5MI37 SIGIRR PTHR11890:SF19 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER SINGLE IG IL-1-RELATED RECEPTOR transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016954.1|UniProtKB=W5NK03 W5NK03 PTHR34034:SF2 PROTEIN FAM180A-RELATED PROTEIN FAM180A LEPOC|Ensembl=ENSLOCG00000018117.1|UniProtKB=W5NNK9 W5NNK9 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000012020.1|UniProtKB=W5N2C2 W5N2C2 PTGDR PTHR11866:SF14 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN D2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004481.1|UniProtKB=W5MAE4 W5MAE4 PTHR10985:SF27 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT 6 (DROSOPHILA) sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014584.1|UniProtKB=W5NBE3 W5NBE3 LRRC49 PTHR45973:SF8 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000016390.1|UniProtKB=W5NHZ7 W5NHZ7 PTHR46669:SF1 LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002096.1|UniProtKB=W5M237 W5M237 PTHR10283:SF62 SOLUTE CARRIER FAMILY 13 MEMBER NA(+)_DICARBOXYLATE COTRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;citrate transmembrane transporter activity#GO:0015137;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 succinate transport#GO:0015744;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;citrate transport#GO:0015746;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825;tricarboxylic acid transport#GO:0006842 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008916.1|UniProtKB=W5MR52 W5MR52 AP3S1 PTHR11753:SF12 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000016465.1|UniProtKB=W5NI85 W5NI85 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014454.1|UniProtKB=W5NAY3 W5NAY3 PTHR24349:SF64 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein kinase binding#GO:0019901;mitogen-activated protein kinase binding#GO:0051019;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;response to cytokine#GO:0034097;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;pattern recognition receptor signaling pathway#GO:0002221;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;nitrogen compound metabolic process#GO:0006807;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;innate immune response-activating signaling pathway#GO:0002758;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Ras Pathway#P04393>MAPKAP#P04564;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K3#P05919 LEPOC|Ensembl=ENSLOCG00000008727.1|UniProtKB=W5MQG3 W5MQG3 PTHR23092:SF24 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4A adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007212.1|UniProtKB=W5MK16 W5MK16 PTHR10177:SF62 CYCLINS CYCLIN-J protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000005280.1|UniProtKB=W5MDA2 W5MDA2 PTHR15838:SF1 NUCLEOLAR PROTEIN OF 40 KDA ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000000978.1|UniProtKB=W5LY90 W5LY90 PTHR31872:SF6 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 LEPOC|Ensembl=ENSLOCG00000011262.1|UniProtKB=W5MZN3 W5MZN3 PTHR21624:SF1 STEROL DESATURASE-RELATED PROTEIN ALKYLGLYCEROL MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;membrane lipid metabolic process#GO:0006643;cellular metabolic process#GO:0044237;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000015930.1|UniProtKB=W5NG56 W5NG56 PTHR12354:SF6 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010868.1|UniProtKB=W5MY77 W5MY77 CACNB2 PTHR11824:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;neuromuscular junction development#GO:0007528;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 LEPOC|Ensembl=ENSLOCG00000014898.1|UniProtKB=W5NCJ0 W5NCJ0 PTHR22993:SF27 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 1 catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000008406.1|UniProtKB=W5MPA8 W5MPA8 GRB14 PTHR11243:SF22 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of signal transduction#GO:0009966;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb14#P00197 LEPOC|Ensembl=ENSLOCG00000018181.1|UniProtKB=W5NNS3 W5NNS3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006267.1|UniProtKB=W5MGR9 W5MGR9 CC2D1A PTHR13076:SF8 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1A LEPOC|Ensembl=ENSLOCG00000001578.1|UniProtKB=W5M099 W5M099 COL26A1 PTHR15427:SF23 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMI DOMAIN-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008041.1|UniProtKB=W5MN07 W5MN07 PLCXD1 PTHR13593:SF112 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 LEPOC|Ensembl=ENSLOCG00000015345.1|UniProtKB=W5NE29 W5NE29 PTHR13773:SF4 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 2 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012115.1|UniProtKB=W5N2P8 W5N2P8 PTHR13479:SF40 30S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010526.1|UniProtKB=W5MWY9 W5MWY9 PTHR23351:SF10 FOS TRANSCRIPTION FACTOR-RELATED JUN DIMERIZATION PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000014372.1|UniProtKB=W5NAN6 W5NAN6 PTHR45704:SF13 RAS-LIKE FAMILY MEMBER 11 SI:DKEYP-59C12.1 LEPOC|Ensembl=ENSLOCG00000011847.1|UniProtKB=W5N1R2 W5N1R2 PTHR45615:SF50 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-16 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000014969.1|UniProtKB=W5NCS6 W5NCS6 PTHR11073:SF37 CALRETICULIN AND CALNEXIN CALNEXIN-LIKE cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;ERAD pathway#GO:0036503;cellular biosynthetic process#GO:0044249;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012982.1|UniProtKB=W5N5U2 W5N5U2 PTHR21467:SF0 PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4 SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000008369.1|UniProtKB=W5MP66 W5MP66 PTHR43107:SF16 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 6-LIKE long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;import into cell#GO:0098657;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017009.1|UniProtKB=W5NK67 W5NK67 PTHR11579:SF7 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000008719.1|UniProtKB=W5MQF8 W5MQF8 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004547.1|UniProtKB=W5MAP0 W5MAP0 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002931.1|UniProtKB=W5M4Z5 W5M4Z5 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;enzyme regulator activity#GO:0030234 response to external biotic stimulus#GO:0043207;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;detection of stimulus#GO:0051606;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;negative regulation of nitrogen compound metabolic process#GO:0051172;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000000106.1|UniProtKB=W5LVF8 W5LVF8 PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015013.1|UniProtKB=W5NCX3 W5NCX3 PTHR45758:SF4 MITOFERRIN-1-RELATED MITOFERRIN-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;iron ion transmembrane transport#GO:0034755;mitochondrial transport#GO:0006839;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012193.1|UniProtKB=W5N2Y3 W5N2Y3 PTHR24369:SF156 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT AND IG DOMAIN CONTAINING 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004856.1|UniProtKB=W5MBS2 W5MBS2 KLHL35 PTHR24412:SF187 KELCH PROTEIN KELCH-LIKE PROTEIN 35 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017671.1|UniProtKB=W5NMB7 W5NMB7 PTHR32341:SF10 INTERFERON-INDUCIBLE GTPASE INTERFERON-INDUCIBLE GTPASE 5 LEPOC|Ensembl=ENSLOCG00000012656.1|UniProtKB=W5N4M6 W5N4M6 WDR70 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003540.1|UniProtKB=W5M738 W5M738 PTHR13422:SF13 SIN3-HDAC COMPLEX-ASSOCIATED FACTOR FAMILY WITH SEQUENCE SIMILARITY 60, MEMBER A regulation of biological process#GO:0050789;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000017700.1|UniProtKB=W5NME6 W5NME6 PTHR22752:SF3 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 135 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014933.1|UniProtKB=W5NCM5 W5NCM5 PTHR13058:SF22 THREE PRIME REPAIR EXONUCLEASE 1, 2 EXODEOXYRIBONUCLEASE III hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010289.1|UniProtKB=W5MW42 W5MW42 PTHR28582:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 LEPOC|Ensembl=ENSLOCG00000001950.1|UniProtKB=W5M1K3 W5M1K3 PTHR28586:SF1 PROTEIN PAXX PROTEIN PAXX DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014984.1|UniProtKB=W5NCT9 W5NCT9 PTHR13817:SF65 TITIN FIBRONECTIN TYPE III DOMAIN CONTAINING 3A-RELATED structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001782.1|UniProtKB=W5M107 W5M107 PTHR20932:SF5 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 3-RELATED endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000171.1|UniProtKB=W5LVN5 W5LVN5 PTHR18884:SF128 SEPTIN SI:CH211-282J17.12-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006105.1|UniProtKB=W5MG70 W5MG70 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009968.1|UniProtKB=W5MUZ0 W5MUZ0 PTHR24131:SF5 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017247.1|UniProtKB=W5NL23 W5NL23 PTHR18870:SF7 PROTEIN TAG-278-RELATED PROTEIN FAM184A LEPOC|Ensembl=ENSLOCG00000008204.1|UniProtKB=W5MNL6 W5MNL6 PTHR11633:SF5 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR C growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 LEPOC|Ensembl=ENSLOCG00000017092.1|UniProtKB=W5NKG3 W5NKG3 PTHR24393:SF5 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM16 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011174.1|UniProtKB=W5MZC6 W5MZC6 PTHR11311:SF8 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7A cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015701.1|UniProtKB=W5NFC0 W5NFC0 PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015808.1|UniProtKB=W5NFQ5 W5NFQ5 PTHR11814:SF33 SULFATE TRANSPORTER PENDRIN inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004979.1|UniProtKB=W5MC90 W5MC90 PTHR19375:SF144 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;endoplasmic reticulum protein-containing complex#GO:0140534;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 LEPOC|Ensembl=ENSLOCG00000014163.1|UniProtKB=W5N9Y9 W5N9Y9 PTHR12968:SF2 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 2 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002557.1|UniProtKB=W5M3P0 W5M3P0 FOXC2 PTHR11829:SF68 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN C1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015478.1|UniProtKB=W5NEJ1 W5NEJ1 PTHR12298:SF4 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED PROGRAMMED CELL DEATH PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015724.1|UniProtKB=W5NFE6 W5NFE6 PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008354.1|UniProtKB=W5MP82 W5MP82 PTHR13743:SF62 BEIGE/BEACH-RELATED NEUROBEACHIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011198.1|UniProtKB=W5MZF6 W5MZF6 PTHR11476:SF7 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014880.1|UniProtKB=W5NCG8 W5NCG8 PTHR18952:SF19 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 12 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000003558.1|UniProtKB=W5M753 W5M753 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000006656.1|UniProtKB=W5MI29 W5MI29 DNAAF1 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000002488.1|UniProtKB=W5M3H3 W5M3H3 PTHR11920:SF464 GUANYLYL CYCLASE GUANYLATE CYCLASE adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;peptide hormone binding#GO:0017046;phosphorus-oxygen lyase activity#GO:0016849;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;hormone binding#GO:0042562 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000007163.1|UniProtKB=W5MJW9 W5MJW9 PTHR12792:SF0 EXTRA SPINDLE POLES 1-RELATED SEPARIN cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic cell cycle process#GO:1903046;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006203.1|UniProtKB=W5MGI0 W5MGI0 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006977.1|UniProtKB=W5MJ85 W5MJ85 PTHR11679:SF27 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 2 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017601.1|UniProtKB=W5NM47 W5NM47 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002069.1|UniProtKB=W5M1Z6 W5M1Z6 GARRE1 PTHR15703:SF3 RIKEN CDNA 4931406P16 GENE GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rac protein signal transduction#GO:0016601 LEPOC|Ensembl=ENSLOCG00000006527.1|UniProtKB=W5MHM4 W5MHM4 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000004015.1|UniProtKB=W5M8V4 W5M8V4 PTHR43108:SF4 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;kidney development#GO:0001822;positive regulation of Wnt signaling pathway#GO:0030177;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;external encapsulating structure organization#GO:0045229;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of cytokine production#GO:0001819;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;regulation of cytokine production#GO:0001817;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cell surface#GO:0009986;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015411.1|UniProtKB=W5NEA4 W5NEA4 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015337.1|UniProtKB=W5NE15 W5NE15 PTHR20929:SF11 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED DYNEIN AXONEMAL INTERMEDIATE CHAIN 7 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000017149.1|UniProtKB=W5NKN4 W5NKN4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003035.1|UniProtKB=W5M5B2 W5M5B2 PTHR44176:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015369.1|UniProtKB=W5NE55 W5NE55 PTHR19282:SF199 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002781.1|UniProtKB=W5M4I1 W5M4I1 PTHR10165:SF41 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004467.1|UniProtKB=W5MAD4 W5MAD4 PTHR24264:SF38 TRYPSIN-RELATED UROKINASE-TYPE PLASMINOGEN ACTIVATOR hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cell adhesion mediated by integrin#GO:0033628 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CCKR signaling map#P06959>uPA#G06974;Plasminogen activating cascade#P00050>uPA#P01243;Blood coagulation#P00011>uPA#P00424;CCKR signaling map#P06959>uPA#G07267;Plasminogen activating cascade#P00050>pro-uPA#P01262;CCKR signaling map#P06959>uPA#P07039;Blood coagulation#P00011>uPAR#P00433 LEPOC|Ensembl=ENSLOCG00000012259.1|UniProtKB=W5N378 W5N378 PTHR15904:SF16 FAM13 PROTEIN FAM13B LEPOC|Ensembl=ENSLOCG00000004381.1|UniProtKB=W5MA22 W5MA22 PTHR15381:SF1 CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED CHONDROITIN SULFATE PROTEOGLYCAN 5 LEPOC|Ensembl=ENSLOCG00000016915.1|UniProtKB=W5NJV4 W5NJV4 PTHR11848:SF139 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 5 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000008416.1|UniProtKB=W5MPC0 W5MPC0 PTHR16223:SF268 TRANSCRIPTION FACTOR BHLH83-RELATED SPERMATOGENESIS- AND OOGENESIS-SPECIFIC BASIC HELIX-LOOP-HELIX-CONTAINING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010237.1|UniProtKB=W5MVX8 W5MVX8 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 snoRNA binding#GO:0030515;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000008480.1|UniProtKB=W5MPL1 W5MPL1 PTHR11003:SF32 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001678.1|UniProtKB=W5M0M6 W5M0M6 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013972.1|UniProtKB=W5N9B4 W5N9B4 PTHR11375:SF1 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006334.1|UniProtKB=W5MGZ1 W5MGZ1 PTHR44662:SF1 WD REPEAT-CONTAINING PROTEIN 81 WD REPEAT-CONTAINING PROTEIN 81 LEPOC|Ensembl=ENSLOCG00000010850.1|UniProtKB=W5MY41 W5MY41 PTHR11306:SF68 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2 lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 LEPOC|Ensembl=ENSLOCG00000017106.1|UniProtKB=W5NKH8 W5NKH8 PTHR10283:SF63 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010390.1|UniProtKB=W5MWH9 W5MWH9 PTHR24083:SF44 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007149.1|UniProtKB=W5MJU5 W5MJU5 PTHR12411:SF947 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018100.1|UniProtKB=W5NNJ2 W5NNJ2 PTHR24226:SF2 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G-PROTEIN COUPLED ESTROGEN RECEPTOR 1 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009427.1|UniProtKB=W5MSZ4 W5MSZ4 PTHR31935:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000014998.1|UniProtKB=W5NCX2 W5NCX2 PTHR16266:SF25 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 3 regulation of anatomical structure morphogenesis#GO:0022603;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cell shape#GO:0008360;regulation of cellular biosynthetic process#GO:0031326;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012334.1|UniProtKB=W5N3H8 W5N3H8 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008456.1|UniProtKB=W5MPI1 W5MPI1 PTHR10177:SF254 CYCLINS CYCLIN-A1 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 LEPOC|Ensembl=ENSLOCG00000008934.1|UniProtKB=W5MR80 W5MR80 PTHR19328:SF27 HEDGEHOG-INTERACTING PROTEIN HEDGEHOG-INTERACTING PROTEIN protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007503.1|UniProtKB=W5ML51 W5ML51 PTHR23324:SF83 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000007965.1|UniProtKB=W5MMR4 W5MMR4 PTHR16134:SF141 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 8 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007797.1|UniProtKB=W5MM59 W5MM59 TTC28 PTHR10098:SF108 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004812.1|UniProtKB=W5MBM0 W5MBM0 PTHR12411:SF1002 CYSTEINE PROTEASE FAMILY C1-RELATED COUNTING FACTOR ASSOCIATED PROTEIN D cysteine-type peptidase activity#GO:0008234;peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;positive regulation of apoptotic signaling pathway#GO:2001235;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005884.1|UniProtKB=W5MFE9 W5MFE9 PTHR47977:SF64 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-30 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017626.1|UniProtKB=W5NM72 W5NM72 PTHR24070:SF213 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010357.1|UniProtKB=W5MWC9 W5MWC9 PTHR24340:SF81 HOMEOBOX PROTEIN NKX H6 FAMILY HOMEOBOX 3B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007848.1|UniProtKB=W5MMC9 W5MMC9 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003639.1|UniProtKB=W5M7G3 W5M7G3 PTHR23359:SF79 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 5 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000000776.1|UniProtKB=W5LXK3 W5LXK3 PTHR23044:SF61 3'-5' EXONUCLEASE ERI1-RELATED 3'-5' EXORIBONUCLEASE 1-RELATED RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000013213.1|UniProtKB=W5N6N8 W5N6N8 PTHR19229:SF234 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1-LIKE transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012370.1|UniProtKB=W5N3L7 W5N3L7 PTHR13902:SF114 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;molecular function inhibitor activity#GO:0140678;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of sodium ion transport#GO:0002028;macromolecule modification#GO:0043412;regulation of metal ion transport#GO:0010959;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of monoatomic ion transport#GO:0043269;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007998.1|UniProtKB=W5MMV3 W5MMV3 PTHR10913:SF44 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 5 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000009615.1|UniProtKB=W5MTP7 W5MTP7 PTHR23406:SF20 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;dicarboxylic acid metabolic process#GO:0043648;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009027.1|UniProtKB=W5MRJ2 W5MRJ2 PTHR14168:SF4 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER EPITHELIAL CELL ADHESION MOLECULE PRECURSOR LEPOC|Ensembl=ENSLOCG00000008837.1|UniProtKB=W5MQU1 W5MQU1 PTHR12489:SF16 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009205.1|UniProtKB=W5MS74 W5MS74 PTHR45622:SF73 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC4-LIKE ISOFORM X1-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015315.1|UniProtKB=W5NDY5 W5NDY5 PTHR23349:SF57 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FACTOR IN THE GERMLINE ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000011308.1|UniProtKB=W5MZT8 W5MZT8 PTHR14728:SF2 PROTEIN AURORA BOREALIS PROTEIN AURORA BOREALIS enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;regulation of mitotic nuclear division#GO:0007088;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cytoskeleton organization#GO:0051493;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of microtubule cytoskeleton organization#GO:0070507;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;positive regulation of catalytic activity#GO:0043085;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008522.1|UniProtKB=W5MPQ7 W5MPQ7 PTHR10159:SF529 DUAL SPECIFICITY PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001348.1|UniProtKB=W5LZG8 W5LZG8 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005974.1|UniProtKB=W5MFR4 W5MFR4 PTHR22957:SF467 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 12 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of organelle organization#GO:0033043;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000010586.1|UniProtKB=W5MX61 W5MX61 PTHR11267:SF114 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX19 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;mesoderm formation#GO:0001707;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;gastrulation#GO:0007369;cellular developmental process#GO:0048869;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;mesoderm development#GO:0007498;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000001195.1|UniProtKB=W5LZ01 W5LZ01 PTHR10465:SF2 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle fusion#GO:0048284 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000013209.1|UniProtKB=W5N6M0 W5N6M0 CATSPERB PTHR14705:SF0 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT BETA membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011885.1|UniProtKB=W5N1V8 W5N1V8 PTHR10751:SF15 GUANYLATE BINDING PROTEIN ATLASTIN-1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011597.1|UniProtKB=W5N0U2 W5N0U2 PTHR15592:SF2 MATRIN 3/NUCLEAR PROTEIN 220-RELATED MATRIN-3 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010857.1|UniProtKB=W5MY47 W5MY47 SH2D4A PTHR14388:SF5 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008163.1|UniProtKB=W5MNE7 W5MNE7 PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000017161.1|UniProtKB=W5NKQ4 W5NKQ4 PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014531.1|UniProtKB=W5NB76 W5NB76 PTHR11759:SF3 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11M ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005952.1|UniProtKB=W5MFP3 W5MFP3 PTHR10037:SF192 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1H calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;positive regulation of secretion#GO:0051047;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;action potential#GO:0001508;regulation of localization#GO:0032879;calcium ion transport#GO:0006816;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000003012.1|UniProtKB=W5M586 W5M586 PTHR10476:SF17 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006937.1|UniProtKB=W5MJ32 W5MJ32 KISS1R PTHR24229:SF107 NEUROPEPTIDES RECEPTOR G-PROTEIN COUPLED RECEPTOR 54-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002181.1|UniProtKB=W5M2E7 W5M2E7 PTHR11521:SF4 TROPONIN T TROPONIN T, FAST SKELETAL MUSCLE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000018232.1|UniProtKB=W5NNX4 W5NNX4 PTHR11863:SF213 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;steroid biosynthetic process#GO:0006694;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016442.1|UniProtKB=W5NI48 W5NI48 PTHR11848:SF143 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000015731.1|UniProtKB=W5NFF7 W5NFF7 PTHR45726:SF3 LEUKOTRIENE A-4 HYDROLASE LEUKOTRIENE A-4 HYDROLASE LEPOC|Ensembl=ENSLOCG00000014993.1|UniProtKB=W5NCV2 W5NCV2 PTHR12963:SF4 THYROID RECEPTOR INTERACTING PROTEIN RELATED ACTIVATING SIGNAL COINTEGRATOR 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000013168.1|UniProtKB=W5N6G5 W5N6G5 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 LEPOC|Ensembl=ENSLOCG00000002493.1|UniProtKB=W5M3H6 W5M3H6 PTHR24061:SF441 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005430.1|UniProtKB=W5MDT8 W5MDT8 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle membrane contact site#GO:0044232;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000016576.1|UniProtKB=W5NIL6 W5NIL6 PTHR14517:SF10 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 2 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000018006.1|UniProtKB=W5NN98 W5NN98 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006423.1|UniProtKB=W5MHA0 W5MHA0 PTHR45946:SF5 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-B1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012158.1|UniProtKB=W5N2U5 W5N2U5 PTHR31433:SF0 PX DOMAIN-CONTAINING PROTEIN 1 PX DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016272.1|UniProtKB=W5NHH6 W5NHH6 PTHR47535:SF9 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of organelle localization#GO:0051656 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000008921.1|UniProtKB=W5MR59 W5MR59 PTHR16026:SF0 CARTILAGE ACIDIC PROTEIN 1 CARTILAGE ACIDIC PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011776.1|UniProtKB=W5N1H3 W5N1H3 PTHR48014:SF20 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN ALPHA protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;activation of protein kinase activity#GO:0032147;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;organic substance transport#GO:0071702;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein export from nucleus#GO:0006611;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;regulation of kinase activity#GO:0043549;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;cellular macromolecule localization#GO:0070727;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;nuclear export#GO:0051168;regulation of protein phosphorylation#GO:0001932;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;positive regulation of kinase activity#GO:0033674;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009616.1|UniProtKB=W5MTP9 W5MTP9 BRD8 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000004894.1|UniProtKB=W5MBY6 W5MBY6 PTHR16308:SF19 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009607.1|UniProtKB=W5MTM8 W5MTM8 CCDC81 PTHR14362:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015326.1|UniProtKB=W5NE02 W5NE02 PTHR11452:SF14 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE A hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 galactosidase#PC00104;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007990.1|UniProtKB=W5MMU2 W5MMU2 PTHR13367:SF28 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE ZRANB1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015414.1|UniProtKB=W5NEB1 W5NEB1 PTHR45632:SF11 LD33804P KELCH-LIKE PROTEIN 9 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;cullin family protein binding#GO:0097602;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of cell division#GO:0051302;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;protein metabolic process#GO:0019538;regulation of cytokinesis#GO:0032465;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012736.1|UniProtKB=W5N4V8 W5N4V8 RANBP3L PTHR23138:SF142 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3B-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015453.1|UniProtKB=W5NEG0 W5NEG0 PTHR10106:SF38 CYTOCHROME B561-RELATED LYSOSOMAL MEMBRANE ASCORBATE-DEPENDENT FERRIREDUCTASE CYB561A3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003392.1|UniProtKB=W5M6L4 W5M6L4 PTHR10751:SF100 GUANYLATE BINDING PROTEIN GUANYLATE BINDING PROTEIN 1 ISOFORM X1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000434.1|UniProtKB=W5LWG7 W5LWG7 PRF1 PTHR46096:SF1 PERFORIN-1 PERFORIN 1.5 wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;cell recognition#GO:0008037;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;T cell mediated immunity#GO:0002456;cell killing#GO:0001906;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;defense response to symbiont#GO:0140546;cell-cell recognition#GO:0009988;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation#GO:0001775;leukocyte mediated cytotoxicity#GO:0001909;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;adaptive immune response#GO:0002250;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;multicellular organismal process#GO:0032501;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;leukocyte activation#GO:0045321 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000018259.1|UniProtKB=W5NP01 W5NP01 PTHR24368:SF62 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 3 head development#GO:0060322;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004806.1|UniProtKB=W5MBL4 W5MBL4 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009543.1|UniProtKB=W5MTF1 W5MTF1 PTHR11937:SF566 ACTIN ACTIN, BETA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000015137.1|UniProtKB=W5NDB9 W5NDB9 CKAP4 PTHR45161:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 4 CYTOSKELETON-ASSOCIATED PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000009228.1|UniProtKB=W5MS98 W5MS98 PTHR43899:SF7 RH59310P 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 LEPOC|Ensembl=ENSLOCG00000006642.1|UniProtKB=W5MI16 W5MI16 PTHR12308:SF37 ANOCTAMIN ANOCTAMIN-9 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000023.1|UniProtKB=W5LV69 W5LV69 PTHR12280:SF23 PANTOTHENATE KINASE PANTOTHENATE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000009179.1|UniProtKB=W5MS35 W5MS35 PTHR24180:SF14 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 45 kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000013535.1|UniProtKB=W5N7U1 W5N7U1 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED CELL DIVISION CONTROL PROTEIN 6 HOMOLOG DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000013175.1|UniProtKB=W5N6H4 W5N6H4 PTHR37457:SF1 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 52 LEPOC|Ensembl=ENSLOCG00000013570.1|UniProtKB=W5N7Y0 W5N7Y0 PTHR10048:SF95 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000016567.1|UniProtKB=W5NIK7 W5NIK7 PTHR16056:SF15 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle microtubule#GO:0005876;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010214.1|UniProtKB=W5MVU7 W5MVU7 PTHR21228:SF4 FAST LEU-RICH DOMAIN-CONTAINING FAS-ACTIVATED SERINE_THREONINE KINASE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA processing#GO:0000963;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014444.1|UniProtKB=W5NAW9 W5NAW9 PTHR18895:SF74 HEMK METHYLTRANSFERASE MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014053.1|UniProtKB=W5N9L3 W5N9L3 PTHR24103:SF624 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 54 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016537.1|UniProtKB=W5NIH0 W5NIH0 PTHR24416:SF257 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE MER signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;phagocytosis#GO:0006909;endocytosis#GO:0006897;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;import into cell#GO:0098657;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010641.1|UniProtKB=W5MXD9 W5MXD9 PTHR42985:SF25 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 monocarboxylic acid transport#GO:0015718;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;lipid localization#GO:0010876;monoatomic ion transport#GO:0006811 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014924.1|UniProtKB=W5NCL5 W5NCL5 PTHR24241:SF4 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002385.1|UniProtKB=W5M335 W5M335 PTHR22977:SF5 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010912.1|UniProtKB=W5MYB9 W5MYB9 PTHR13713:SF60 SIALYLTRANSFERASE LACTOSYLCERAMIDE ALPHA-2,3-SIALYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003393.1|UniProtKB=W5M6L3 W5M6L3 PTHR10340:SF25 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005933.1|UniProtKB=W5MFK3 W5MFK3 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008432.1|UniProtKB=W5MPE3 W5MPE3 PTHR45706:SF3 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 21 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011309.1|UniProtKB=W5MZT5 W5MZT5 PTHR24028:SF236 CADHERIN-87A PROTOCADHERIN GAMMA-C3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000016961.1|UniProtKB=W5NK09 W5NK09 PTHR45740:SF13 POLY [ADP-RIBOSE] POLYMERASE POLY (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER 12B transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009404.1|UniProtKB=W5MSW2 W5MSW2 PTHR21237:SF10 GRPE PROTEIN GRPE PROTEIN HOMOLOG 2, MITOCHONDRIAL nucleotide binding#GO:0000166;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017542.1|UniProtKB=W5NLY8 W5NLY8 PTHR12611:SF3 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016034.1|UniProtKB=W5NGJ7 W5NGJ7 PTHR10824:SF36 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 17-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000000042.1|UniProtKB=W5LV93 W5LV93 PTHR24253:SF144 TRANSMEMBRANE PROTEASE SERINE CHYMOTRYPSIN-LIKE PROTEASE CTRL-1-RELATED serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000018202.1|UniProtKB=W5NNU4 W5NNU4 PTHR24373:SF394 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000751.1|UniProtKB=W5LXH6 W5LXH6 PTHR12737:SF16 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE N(G),N(G)-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 2 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 positive regulation of nitrogen compound metabolic process#GO:0051173;oxoacid metabolic process#GO:0043436;regulation of nitrogen compound metabolic process#GO:0051171;arginine metabolic process#GO:0006525;positive regulation of cellular metabolic process#GO:0031325;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;alpha-amino acid metabolic process#GO:1901605;carboxylic acid metabolic process#GO:0019752;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;amino acid metabolic process#GO:0006520;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015115.1|UniProtKB=W5ND92 W5ND92 PTHR12011:SF277 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003471.1|UniProtKB=W5M6W4 W5M6W4 PTHR45840:SF4 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 LEPOC|Ensembl=ENSLOCG00000010699.1|UniProtKB=W5MXJ7 W5MXJ7 PTHR10300:SF4 CALCIPRESSIN CALCIPRESSIN-1 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000017822.1|UniProtKB=W5NMR6 W5NMR6 PTHR24247:SF131 5-HYDROXYTRYPTAMINE RECEPTOR ODORANT RECEPTOR-RELATED cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012730.1|UniProtKB=W5N4V3 W5N4V3 RAB7B PTHR47981:SF22 RAB FAMILY RAS-RELATED PROTEIN RAB-7B lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012697.1|UniProtKB=W5N4R7 W5N4R7 CPLANE1 PTHR14492:SF4 JBTS17 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 1 LEPOC|Ensembl=ENSLOCG00000011110.1|UniProtKB=W5MZ41 W5MZ41 PTHR21585:SF0 FULL-LENGTH CDNA CLONE CS0DC025YL05 OF NEUROBLASTOMA ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000010716.1|UniProtKB=W5MXN0 W5MXN0 FAM133B PTHR31911:SF1 PROTEIN FAM133 FAMILY WITH SEQUENCE SIMILARITY 133 MEMBER B-RELATED RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016392.1|UniProtKB=W5NHY6 W5NHY6 PTHR46808:SF1 H2.0-LIKE HOMEOBOX PROTEIN H2.0-LIKE HOMEOBOX PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000002516.1|UniProtKB=W5M3J1 W5M3J1 PTHR24248:SF14 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1D ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;system process#GO:0003008;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of system process#GO:0044057;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000013636.1|UniProtKB=W5N858 W5N858 SLC16A2 PTHR11360:SF123 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 8 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008501.1|UniProtKB=W5MPN4 W5MPN4 PTHR45971:SF3 PHOX (PX) DOMAIN-CONTAINING PROTEIN RUN DOMAIN BECLIN-1-INTERACTING AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;regulation of endocytosis#GO:0030100;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;negative regulation of cellular catabolic process#GO:0031330;regulation of localization#GO:0032879;regulation of protein-containing complex disassembly#GO:0043244;regulation of cellular component organization#GO:0051128;regulation of macroautophagy#GO:0016241;negative regulation of metabolic process#GO:0009892;negative regulation of transport#GO:0051051;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of catabolic process#GO:0009895;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;negative regulation of protein-containing complex disassembly#GO:0043242;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;negative regulation of endocytosis#GO:0045806;regulation of autophagosome maturation#GO:1901096;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008681.1|UniProtKB=W5MQC5 W5MQC5 PTHR14226:SF26 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009557.1|UniProtKB=W5MTI4 W5MTI4 PTHR24393:SF69 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE MECOM DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003948.1|UniProtKB=W5M8K8 W5M8K8 C11orf54 PTHR13204:SF1 PTD012 PROTEIN ESTER HYDROLASE C11ORF54 cation binding#GO:0043169;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001650.1|UniProtKB=W5M0J7 W5M0J7 COL6A6 PTHR24020:SF86 COLLAGEN ALPHA COLLAGEN, TYPE VI, ALPHA 4 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000017457.1|UniProtKB=W5NLQ3 W5NLQ3 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013109.1|UniProtKB=W5N688 W5N688 PTHR46260:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8B cell division#GO:0051301;nuclear chromosome segregation#GO:0098813;nuclear division#GO:0000280;mitotic cytokinetic process#GO:1902410;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytokinesis#GO:0000910 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;midbody#GO:0030496;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004476.1|UniProtKB=W5MAE9 W5MAE9 PTHR24082:SF39 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Angiogenesis#P00005>PAR#P00192 LEPOC|Ensembl=ENSLOCG00000001543.1|UniProtKB=W5M059 W5M059 FAM81B PTHR22420:SF5 PROTEIN FAM81A PROTEIN FAM81B LEPOC|Ensembl=ENSLOCG00000012483.1|UniProtKB=W5N406 W5N406 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008488.1|UniProtKB=W5MPM2 W5MPM2 PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000005244.1|UniProtKB=W5MD58 W5MD58 PTHR18875:SF3 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO CENTROSOMAL PROTEIN OF 63 KDA cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;centriole assembly#GO:0098534;epithelium development#GO:0060429;developmental process#GO:0032502;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;tissue development#GO:0009888;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006685.1|UniProtKB=W5MI64 W5MI64 PTHR10019:SF5 SNF5 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000012207.1|UniProtKB=W5N321 W5N321 PTHR22969:SF10 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT EPSILON transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>IKKepsilon#P01372;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 LEPOC|Ensembl=ENSLOCG00000015211.1|UniProtKB=W5NDL6 W5NDL6 PTHR38487:SF1 TESTIS EXPRESSED 11 PROTEIN ZIP4 HOMOLOG LEPOC|Ensembl=ENSLOCG00000008113.1|UniProtKB=W5MNC0 W5MNC0 PTHR24270:SF23 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;catabolic process#GO:0009056;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;multicellular organismal process#GO:0032501;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 LEPOC|Ensembl=ENSLOCG00000005807.1|UniProtKB=W5MF63 W5MF63 PTHR24115:SF937 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5A cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515 neuron projection guidance#GO:0097485;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;synaptic vesicle transport#GO:0048489;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;microtubule-based transport#GO:0099111;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;generation of neurons#GO:0048699;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017726.1|UniProtKB=W5NMH1 W5NMH1 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114 LEPOC|Ensembl=ENSLOCG00000004318.1|UniProtKB=W5M9W2 W5M9W2 PTHR12039:SF7 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000005369.1|UniProtKB=W5MDL3 W5MDL3 PTHR15600:SF42 SACSIN SACSIN heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 LEPOC|Ensembl=ENSLOCG00000017152.1|UniProtKB=W5NKN7 W5NKN7 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011594.1|UniProtKB=W5N0V5 W5N0V5 PTHR45999:SF3 UNC-13-4A, ISOFORM B PROTEIN UNC-13 HOMOLOG D localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cellular anatomical entity#GO:0110165;organelle#GO:0043226;secretory vesicle#GO:0099503;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Synaptic vesicle trafficking#P05734>Munc13#P05773 LEPOC|Ensembl=ENSLOCG00000002630.1|UniProtKB=W5M3Z3 W5M3Z3 PTHR46046:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP9 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009940.1|UniProtKB=W5MUU2 W5MUU2 PTHR47730:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 29 SMALL INTEGRAL MEMBRANE PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000004108.1|UniProtKB=W5M959 W5M959 PTHR13600:SF21 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002435.1|UniProtKB=W5M3A9 W5M3A9 PTHR15739:SF4 ZINC FINGER PROTEIN F-BOX ONLY PROTEIN 41 LEPOC|Ensembl=ENSLOCG00000018240.1|UniProtKB=W5NNY2 W5NNY2 NPY4R2 PTHR24241:SF145 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015923.1|UniProtKB=W5NG45 W5NG45 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011181.1|UniProtKB=W5MZC7 W5MZC7 PTHR24103:SF595 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 14 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014370.1|UniProtKB=W5NAN4 W5NAN4 PTHR47138:SF1 PERILIPIN-1 PERILIPIN-1 LEPOC|Ensembl=ENSLOCG00000009487.1|UniProtKB=W5MT76 W5MT76 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012888.1|UniProtKB=W5N5F8 W5N5F8 PTHR24412:SF192 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011506.1|UniProtKB=W5N0H8 W5N0H8 PTHR24028:SF247 CADHERIN-87A PROTOCADHERIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000003478.1|UniProtKB=W5M6W9 W5M6W9 PTHR14132:SF14 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 5 transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transporter activity#GO:0032409 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012977.1|UniProtKB=W5N5S5 W5N5S5 PTHR11461:SF191 SERINE PROTEASE INHIBITOR, SERPIN PROTEIN Z-DEPENDENT PROTEASE INHIBITOR extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>ZPI#P00425 LEPOC|Ensembl=ENSLOCG00000014120.1|UniProtKB=W5N9T7 W5N9T7 PTHR36129:SF3 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED SUBFAMILY NOT NAMED transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010596.1|UniProtKB=W5MX68 W5MX68 PTHR31457:SF2 METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN CYANOCOBALAMIN REDUCTASE _ ALKYLCOBALAMIN DEALKYLASE nucleotide binding#GO:0000166;demethylase activity#GO:0032451;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on metal ions#GO:0016722;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012564.1|UniProtKB=W5N4A9 W5N4A9 PTHR28602:SF1 ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR LEPOC|Ensembl=ENSLOCG00000013741.1|UniProtKB=W5N8K4 W5N8K4 PTHR24072:SF124 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrion organization#GO:0007005;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014010.1|UniProtKB=W5N9F9 W5N9F9 ZNF750 PTHR14678:SF1 PROLINE-RICH PROTEIN 35-RELATED ZINC FINGER PROTEIN 750 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein-containing complex binding#GO:0044877;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;epidermis development#GO:0008544;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015679.1|UniProtKB=W5NF93 W5NF93 PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA_RNA-BINDING PROTEIN KIN17 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007098.1|UniProtKB=W5MJN7 W5MJN7 PTHR43690:SF18 NARDILYSIN INSULIN-DEGRADING ENZYME-RELATED metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013762.1|UniProtKB=W5N8L1 W5N8L1 PTHR25465:SF30 B-BOX DOMAIN CONTAINING FINTRIM FAMILY, MEMBER 82 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013134.1|UniProtKB=W5N6C1 W5N6C1 PTHR10460:SF60 ABL INTERACTOR FAMILY MEMBER ABI GENE FAMILY MEMBER 3 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;SH3 domain binding#GO:0017124;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell motility#GO:0048870;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477 cytoplasm#GO:0005737;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;actin-based cell projection#GO:0098858;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010315.1|UniProtKB=W5MW77 W5MW77 PTHR18863:SF5 TSEC-2-RELATED TESTIS EXPRESSED GENE 21 LEPOC|Ensembl=ENSLOCG00000004825.1|UniProtKB=W5MBN7 W5MBN7 PTHR16500:SF3 BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015505.1|UniProtKB=W5NEM6 W5NEM6 PTHR38537:SF5 JITTERBUG, ISOFORM N FILAMIN-A Nicotine pharmacodynamics pathway#P06587>FLNA#P06601;Integrin signalling pathway#P00034>Filamin#P00914;Dopamine receptor mediated signaling pathway#P05912>FLNA#P05959 LEPOC|Ensembl=ENSLOCG00000012428.1|UniProtKB=W5N3U3 W5N3U3 PTHR24270:SF27 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000012916.1|UniProtKB=W5N5J5 W5N5J5 HPGDS PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013404.1|UniProtKB=W5N7B6 W5N7B6 PTHR23268:SF102 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007605.1|UniProtKB=W5MLG6 W5MLG6 PTHR47305:SF1 BEN DOMAIN-CONTAINING PROTEIN 2 BEN DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013084.1|UniProtKB=W5N663 W5N663 PTHR12591:SF2 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE 3 hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001373.1|UniProtKB=W5LZJ9 W5LZJ9 PTHR11106:SF93 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;cellular response to stimulus#GO:0051716;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;glycosyl compound metabolic process#GO:1901657;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017701.1|UniProtKB=W5NME7 W5NME7 PTHR24229:SF38 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;response to estradiol#GO:0032355;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000009049.1|UniProtKB=W5MRM3 W5MRM3 PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;ligase activity#GO:0016874;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;catalytic activity, acting on a nucleic acid#GO:0140640;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014472.1|UniProtKB=W5NB06 W5NB06 PTHR24418:SF263 TYROSINE-PROTEIN KINASE NON-RECEPTOR TYROSINE-PROTEIN KINASE TNK1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000003838.1|UniProtKB=W5M879 W5M879 PTHR11267:SF169 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR T-A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;mesoderm formation#GO:0001707;epithelium development#GO:0060429;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;gastrulation#GO:0007369;cellular developmental process#GO:0048869;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;mesoderm development#GO:0007498;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000007369.1|UniProtKB=W5MKM4 W5MKM4 PTHR19143:SF209 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 6 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013958.1|UniProtKB=W5N998 W5N998 PTHR21227:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000015758.1|UniProtKB=W5NFJ1 W5NFJ1 PTHR17613:SF8 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000014362.1|UniProtKB=W5NAM7 W5NAM7 PTHR22838:SF4 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 13 protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008461.1|UniProtKB=W5MPI6 W5MPI6 PTHR45876:SF1 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008025.1|UniProtKB=W5MMY5 W5MMY5 PTHR11523:SF47 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009131.1|UniProtKB=W5MRX5 W5MRX5 PTHR12566:SF2 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;synapse#GO:0045202;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005386.1|UniProtKB=W5MDN5 W5MDN5 PTHR23093:SF18 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 GLUTAMATE RICH 6 LEPOC|Ensembl=ENSLOCG00000003782.1|UniProtKB=W5M812 W5M812 PTHR11818:SF122 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN A structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015192.1|UniProtKB=W5NDI9 W5NDI9 PTHR19308:SF33 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN CONTAINING 10 LEPOC|Ensembl=ENSLOCG00000001905.1|UniProtKB=W5M1G9 W5M1G9 PTHR43226:SF1 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO DIPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007960.1|UniProtKB=W5MMS3 W5MMS3 PTHR24241:SF135 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017460.1|UniProtKB=W5NLQ6 W5NLQ6 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006735.1|UniProtKB=W5MIC6 W5MIC6 PTHR10194:SF96 RAS GTPASE-ACTIVATING PROTEINS RAS PROTEIN ACTIVATOR LIKE-3 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005120.1|UniProtKB=W5MCS1 W5MCS1 PTHR23411:SF35 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT MU protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;humoral immune response#GO:0006959;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;antibacterial humoral response#GO:0019731;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;defense response to bacterium#GO:0042742;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;complement activation#GO:0006956 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 immunoglobulin receptor superfamily#PC00124 B cell activation#P00010>mIgM#P00389 LEPOC|Ensembl=ENSLOCG00000009769.1|UniProtKB=W5MU85 W5MU85 PTHR12784:SF3 STEERIN NEURON NAVIGATOR 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;cell motility#GO:0048870;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron migration#GO:0001764;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;main axon#GO:0044304;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001879.1|UniProtKB=W5M1B9 W5M1B9 PTHR13359:SF2 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML40 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010504.1|UniProtKB=W5MWW4 W5MWW4 ZNF804B PTHR17614:SF12 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017519.1|UniProtKB=W5NLW5 W5NLW5 PTHR24369:SF217 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3B-LIKE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017640.1|UniProtKB=W5NM86 W5NM86 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000003822.1|UniProtKB=W5M857 W5M857 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005274.1|UniProtKB=W5MD97 W5MD97 PTHR22951:SF16 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;establishment of organelle localization#GO:0051656;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000011088.1|UniProtKB=W5MZ11 W5MZ11 PTHR21077:SF7 EME1 PROTEIN CROSSOVER JUNCTION ENDONUCLEASE EME1 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;replication fork processing#GO:0031297;intracellular signal transduction#GO:0035556;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;DNA-templated DNA replication#GO:0006261;reciprocal meiotic recombination#GO:0007131;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic DNA integrity checkpoint signaling#GO:0044774;homologous recombination#GO:0035825;DNA replication#GO:0006260;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endonuclease complex#GO:1905348 LEPOC|Ensembl=ENSLOCG00000016133.1|UniProtKB=W5NGW9 W5NGW9 PTHR15583:SF13 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR A signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012304.1|UniProtKB=W5N3E8 W5N3E8 PTHR45685:SF2 HELICASE SRCAP-RELATED CHROMATIN-REMODELING ATPASE INO80 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;protein-containing complex organization#GO:0043933;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000016839.1|UniProtKB=W5NJK5 W5NJK5 PTHR19282:SF397 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002669.1|UniProtKB=W5M429 W5M429 PTHR22662:SF0 TIRAP TOLL_INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN Toll receptor signaling pathway#P00054>TIRAP#P01350 LEPOC|Ensembl=ENSLOCG00000006145.1|UniProtKB=W5MGB4 W5MGB4 PTHR12305:SF81 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway#P00059>PTEN#G01579;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PTEN#P00849;Hypoxia response via HIF activation#P00030>PTEN#P00824;PI3 kinase pathway#P00048>PTEN#P01189;CCKR signaling map#P06959>PTEN#P07071;p53 pathway feedback loops 2#P04398>PTEN#P04658 LEPOC|Ensembl=ENSLOCG00000015299.1|UniProtKB=W5NDW9 W5NDW9 PTHR24347:SF403 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Gonadotropin-releasing hormone receptor pathway#P06664>Ca/CaMK II#P06735;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 LEPOC|Ensembl=ENSLOCG00000006622.1|UniProtKB=W5MI14 W5MI14 PTHR22692:SF34 MYOSIN VII, XV MYOSIN VIIA actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000001623.1|UniProtKB=W5M0J5 W5M0J5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004930.1|UniProtKB=W5MC22 W5MC22 PTHR31705:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007317.1|UniProtKB=W5MKF3 W5MKF3 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016187.1|UniProtKB=W5NH45 W5NH45 PTHR11532:SF84 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE M metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004974.1|UniProtKB=W5MC87 W5MC87 PTHR17550:SF8 E3 UBIQUITIN-PROTEIN LIGASE TTC3 RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007051.1|UniProtKB=W5MJH4 W5MJH4 HHEX PTHR24324:SF5 HOMEOBOX PROTEIN HHEX HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007043.1|UniProtKB=W5MJI5 W5MJI5 PTHR45664:SF5 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-D3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015961.1|UniProtKB=W5NG96 W5NG96 PTHR11630:SF106 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;mitotic DNA replication initiation#GO:1902975;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000087.1|UniProtKB=W5LVE0 W5LVE0 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000004543.1|UniProtKB=W5MAM4 W5MAM4 C21orf91 PTHR15961:SF3 PROTEIN EURL HOMOLOG PROTEIN EURL HOMOLOG LEPOC|Ensembl=ENSLOCG00000009821.1|UniProtKB=W5MUE3 W5MUE3 PTHR16089:SF11 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006208.1|UniProtKB=W5MGK9 W5MGK9 PTHR46075:SF4 CHIMERIN FAMILY MEMBER BETA-CHIMAERIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 LEPOC|Ensembl=ENSLOCG00000000576.1|UniProtKB=W5LWY0 W5LWY0 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003832.1|UniProtKB=W5M875 W5M875 PTHR24253:SF86 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 3 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003684.1|UniProtKB=W5M7L1 W5M7L1 C19orf44 PTHR22409:SF2 CHROMOSOME 19 OPEN READING FRAME 44 CHROMOSOME 19 OPEN READING FRAME 44 LEPOC|Ensembl=ENSLOCG00000009901.1|UniProtKB=W5MUN8 W5MUN8 PTHR11454:SF9 INSULIN/INSULIN GROWTH FACTOR INSULIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 LEPOC|Ensembl=ENSLOCG00000000936.1|UniProtKB=W5LY58 W5LY58 PTHR11091:SF0 OXIDOREDUCTASE-RELATED MALATE DEHYDROGENASE oxidoreductase#PC00176 Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138;TCA cycle#P00051>Malate Dehydrogenase#P01270;Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820 LEPOC|Ensembl=ENSLOCG00000003736.1|UniProtKB=W5M7T2 W5M7T2 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016506.1|UniProtKB=W5NID5 W5NID5 PTHR11208:SF152 RNA-BINDING PROTEIN RELATED PROTEIN QUAKING-B-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010344.1|UniProtKB=W5MWC2 W5MWC2 PTHR24064:SF222 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 4 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009282.1|UniProtKB=W5MSG8 W5MSG8 PTHR10747:SF26 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000002624.1|UniProtKB=W5M3X9 W5M3X9 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012212.1|UniProtKB=W5N324 W5N324 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002305.1|UniProtKB=W5M2U0 W5M2U0 PTHR11360:SF255 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 2 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001687.1|UniProtKB=W5M0N1 W5M0N1 PTHR14789:SF4 CHONDROLECTIN VARIANT CHODLFDELTAE. ENDOSIALIN extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009871.1|UniProtKB=W5MUK7 W5MUK7 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE INACTIVE ADP-RIBOSYLTRANSFERASE ARH2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003041.1|UniProtKB=W5M5E7 W5M5E7 PTHR10063:SF0 TUBERIN TUBERIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 p53 pathway by glucose deprivation#P04397>TSC2#P04644;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494;p53 pathway by glucose deprivation#P04397>TSC2#G04706 LEPOC|Ensembl=ENSLOCG00000001434.1|UniProtKB=W5LZT3 W5LZT3 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016304.1|UniProtKB=W5NHL5 W5NHL5 PTHR19957:SF136 SYNTAXIN SYNTAXIN 11B, TANDEM DUPLICATE 1-RELATED protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013969.1|UniProtKB=W5N9A9 W5N9A9 PTHR13932:SF5 COPROPORPHYRINIGEN III OXIDASE RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Coproporphyrinogen oxidase (oxygen independent)#P02970 LEPOC|Ensembl=ENSLOCG00000008423.1|UniProtKB=W5MPD6 W5MPD6 PTHR42707:SF2 ACYL-COA DEHYDROGENASE ACD11 DEHYDROGENASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007475.1|UniProtKB=W5ML14 W5ML14 PTHR11211:SF3 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN MOHAWK sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012832.1|UniProtKB=W5N586 W5N586 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION_NOCUT CHECKPOINT REGULATOR LEPOC|Ensembl=ENSLOCG00000004867.1|UniProtKB=W5MBU2 W5MBU2 PTHR12714:SF9 PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015688.1|UniProtKB=W5NFA4 W5NFA4 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;translation#GO:0006412;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA methylation#GO:0001510 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016253.1|UniProtKB=W5NHD3 W5NHD3 PTHR18842:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000004600.1|UniProtKB=W5MAW1 W5MAW1 PRDM15 PTHR24384:SF193 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED PR_SET DOMAIN 15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006148.1|UniProtKB=W5MGD6 W5MGD6 PTHR24012:SF786 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011398.1|UniProtKB=W5N054 W5N054 PTHR43836:SF3 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;catecholamine metabolic process#GO:0006584;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Dopamine receptor mediated signaling pathway#P05912>COMT#P05944;Adrenaline and noradrenaline biosynthesis#P00001>COMT#P00069 LEPOC|Ensembl=ENSLOCG00000005510.1|UniProtKB=W5ME45 W5ME45 PTHR28618:SF1 CENTROSOMAL PROTEIN POC5 CENTROSOMAL PROTEIN POC5 LEPOC|Ensembl=ENSLOCG00000016318.1|UniProtKB=W5NHN3 W5NHN3 PTHR12268:SF22 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN BETA biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015548.1|UniProtKB=W5NET2 W5NET2 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 LEPOC|Ensembl=ENSLOCG00000003116.1|UniProtKB=W5M5L5 W5M5L5 PTHR22961:SF16 SER/THR PROTEIN KINASE-TRB SERINE_THREONINE-PROTEIN KINASE 40 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007375.1|UniProtKB=W5MKP8 W5MKP8 CCDC63 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 LEPOC|Ensembl=ENSLOCG00000011800.1|UniProtKB=W5N1J7 W5N1J7 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000015890.1|UniProtKB=W5NG08 W5NG08 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED LEPOC|Ensembl=ENSLOCG00000018141.1|UniProtKB=W5NNN3 W5NNN3 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012568.1|UniProtKB=W5N4C2 W5N4C2 PTHR45888:SF1 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2C N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;histone H3K4 methyltransferase activity#GO:0042800;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000016419.1|UniProtKB=W5NI18 W5NI18 SLC38A1 PTHR22950:SF184 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014492.1|UniProtKB=W5NB28 W5NB28 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000005246.1|UniProtKB=W5MD62 W5MD62 PTHR13866:SF18 SPARC OSTEONECTIN TESTICAN-2 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000012188.1|UniProtKB=W5N2X9 W5N2X9 PTHR36688:SF1 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014313.1|UniProtKB=W5NAG5 W5NAG5 PTHR13948:SF4 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003617.1|UniProtKB=W5M7D9 W5M7D9 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000010841.1|UniProtKB=W5MY34 W5MY34 PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE RFWD3-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000260.1|UniProtKB=W5LVX8 W5LVX8 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017489.1|UniProtKB=W5NLT5 W5NLT5 PTHR24232:SF86 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 174-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008252.1|UniProtKB=W5MNQ8 W5MNQ8 PTHR12663:SF1 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG B DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic sister chromatid cohesion#GO:0007064;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cell cycle#GO:0007049;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001583.1|UniProtKB=W5M0B0 W5M0B0 PTHR15225:SF8 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN RNA-BINDING PROTEIN 43 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000007151.1|UniProtKB=W5MJW0 W5MJW0 PTHR11675:SF7 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 4 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017212.1|UniProtKB=W5NKX1 W5NKX1 PTHR10642:SF26 RIBONUCLEASE H1 RIBONUCLEASE H1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DNA replication#P00017>RNase H#P00538 LEPOC|Ensembl=ENSLOCG00000015234.1|UniProtKB=W5NDN6 W5NDN6 PTHR23055:SF85 CALCIUM BINDING PROTEINS SI:CH211-245J22.3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000016083.1|UniProtKB=W5NGQ7 W5NGQ7 PTHR15698:SF9 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002595.1|UniProtKB=W5M3U3 W5M3U3 PTHR46186:SF13 CYSTATIN SI:BUSM1-57F23.1 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000005146.1|UniProtKB=W5MCT9 W5MCT9 PTHR16518:SF4 G-PROTEIN COUPLED RECEPTOR 153, 162 G-PROTEIN COUPLED RECEPTOR 153 ISOFORM X1-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017148.1|UniProtKB=W5NKN3 W5NKN3 PTHR21528:SF0 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000000885.1|UniProtKB=W5LXX7 W5LXX7 PTHR13195:SF0 PSEUDOURIDINE SYNTHASE-RELATED PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000007150.1|UniProtKB=W5MJU4 W5MJU4 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A INNER CENTROMERE PROTEIN A-LIKE ISOFORM X1-RELATED regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003831.1|UniProtKB=W5M863 W5M863 PTHR11339:SF374 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED ZONADHESIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006010.1|UniProtKB=W5MFU9 W5MFU9 PTHR19433:SF85 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 17-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015406.1|UniProtKB=W5NE97 W5NE97 PTHR24247:SF88 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005659.1|UniProtKB=W5MEM4 W5MEM4 PTHR23359:SF167 NUCLEOTIDE KINASE ADENYLATE KINASE 8 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153 LEPOC|Ensembl=ENSLOCG00000003212.1|UniProtKB=W5M600 W5M600 MOB3B PTHR22599:SF22 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3B protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000001588.1|UniProtKB=W5M0C7 W5M0C7 PTHR11915:SF432 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 muscle structure development#GO:0061061;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;Z disc#GO:0030018;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cortical actin cytoskeleton#GO:0030864;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cell projection#GO:0042995;cytoskeleton#GO:0005856;myofibril#GO:0030016;plasma membrane#GO:0005886;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000016062.1|UniProtKB=W5NGN1 W5NGN1 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007587.1|UniProtKB=W5MLE8 W5MLE8 PTHR20913:SF11 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE RAB-GAP TBC DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000017653.1|UniProtKB=W5NM99 W5NM99 PTHR26451:SF896 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008346.1|UniProtKB=W5MP34 W5MP34 PTHR43107:SF10 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 6 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;import into cell#GO:0098657;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000991.1|UniProtKB=W5LYB2 W5LYB2 PTHR43903:SF2 NEUROLIGIN NEUROLIGIN-1 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012496.1|UniProtKB=W5N430 W5N430 PTHR24240:SF72 OPSIN MELANOPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013270.1|UniProtKB=W5N6U5 W5N6U5 ARF4 PTHR11711:SF110 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 4 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000017063.1|UniProtKB=W5NKC8 W5NKC8 PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012711.1|UniProtKB=W5N4T0 W5N4T0 PTHR21258:SF39 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;growth factor receptor binding#GO:0070851;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;fibroblast growth factor receptor binding#GO:0005104 fibroblast growth factor receptor signaling pathway#GO:0008543;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular response to fibroblast growth factor stimulus#GO:0044344;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>FRS2#P00635;Angiogenesis#P00005>FRS-2#P00240 LEPOC|Ensembl=ENSLOCG00000015047.1|UniProtKB=W5ND09 W5ND09 PTHR44090:SF1 WD REPEAT-CONTAINING PROTEIN 61 SUPERKILLER COMPLEX PROTEIN 8 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004880.1|UniProtKB=W5MBV9 W5MBV9 PTHR24300:SF395 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010829.1|UniProtKB=W5MY20 W5MY20 PTHR10953:SF4 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000000160.1|UniProtKB=W5LVM2 W5LVM2 PTHR45755:SF4 FAMILY NOT NAMED ZINC TRANSPORTER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 LEPOC|Ensembl=ENSLOCG00000011707.1|UniProtKB=W5N180 W5N180 FAM117A PTHR14972:SF7 AGAP011572-PA PROTEIN FAM117A LEPOC|Ensembl=ENSLOCG00000004008.1|UniProtKB=W5M8S8 W5M8S8 PTHR10689:SF9 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 PROSTAGLANDIN E SYNTHASE transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014838.1|UniProtKB=W5NCB2 W5NCB2 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 muscle organ development#GO:0007517;muscle cell differentiation#GO:0042692;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;cell development#GO:0048468;muscle cell development#GO:0055001;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000002033.1|UniProtKB=W5M1W0 W5M1W0 PTHR12203:SF18 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 3 transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000003457.1|UniProtKB=W5M6U3 W5M6U3 ANXA10 PTHR10502:SF100 ANNEXIN ANNEXIN A10 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000009339.1|UniProtKB=W5MSQ2 W5MSQ2 PTHR43731:SF14 RHOMBOID PROTEASE PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006493.1|UniProtKB=W5MHI5 W5MHI5 PTHR12322:SF76 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;regulation of DNA-templated transcription#GO:0006355;multicellular organism reproduction#GO:0032504;sex differentiation#GO:0007548;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015926.1|UniProtKB=W5NG49 W5NG49 PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004351.1|UniProtKB=W5MA10 W5MA10 PTHR31431:SF1 NUCLEOPORIN NUP188 HOMOLOG NUCLEOPORIN NUP188 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018320.1|UniProtKB=W5NP62 W5NP62 PTHR18884:SF128 SEPTIN SI:CH211-282J17.12-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006941.1|UniProtKB=W5MJ44 W5MJ44 TMC7 PTHR23302:SF42 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006312.1|UniProtKB=W5MGV8 W5MGV8 FAM78A PTHR31655:SF3 PROTEIN FAM78A PROTEIN FAM78A LEPOC|Ensembl=ENSLOCG00000012883.1|UniProtKB=W5N5G0 W5N5G0 PTHR45745:SF3 PHOSPHOMANNOMUTASE 45A PHOSPHOPENTOMUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;purine-containing compound biosynthetic process#GO:0072522;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;glycosyl compound metabolic process#GO:1901657;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000015739.1|UniProtKB=W5NFG6 W5NFG6 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000017842.1|UniProtKB=W5NMT6 W5NMT6 PTHR11711:SF119 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4C carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000002531.1|UniProtKB=W5M3M0 W5M3M0 PTHR46698:SF4 CROSSVEINLESS 2 CROSSVEINLESS 2 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000017231.1|UniProtKB=W5NL04 W5NL04 ACP1 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008235.1|UniProtKB=W5MNN9 W5MNN9 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010979.1|UniProtKB=W5MYK8 W5MYK8 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribosomal protein#PC00202;translational protein#PC00263 Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000000794.1|UniProtKB=W5LXM4 W5LXM4 PTHR10489:SF618 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 5 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000013715.1|UniProtKB=W5N8F8 W5N8F8 PTHR24064:SF222 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 4 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004423.1|UniProtKB=W5MA75 W5MA75 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 LEPOC|Ensembl=ENSLOCG00000000911.1|UniProtKB=W5LY12 W5LY12 PTHR14879:SF2 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RIFIFYLIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;protein catabolic process#GO:0030163;regulation of apoptotic signaling pathway#GO:2001233;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;proteasomal protein catabolic process#GO:0010498;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;negative regulation of signaling#GO:0023057;negative regulation of endopeptidase activity#GO:0010951;regulation of extrinsic apoptotic signaling pathway#GO:2001236;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;post-translational protein modification#GO:0043687;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008799.1|UniProtKB=W5MQQ0 W5MQQ0 PTHR24343:SF303 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000013204.1|UniProtKB=W5N6L0 W5N6L0 PTHR23503:SF99 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001259.1|UniProtKB=W5LZ76 W5LZ76 PTHR11328:SF28 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017978.1|UniProtKB=W5NN70 W5NN70 PTHR24366:SF127 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 1 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000006672.1|UniProtKB=W5MI47 W5MI47 PTHR24347:SF412 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 LEPOC|Ensembl=ENSLOCG00000011535.1|UniProtKB=W5N0L3 W5N0L3 PTHR23310:SF53 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000012082.1|UniProtKB=W5N2L4 W5N2L4 PTHR19359:SF150 CYTOCHROME B5 CYTOCHROME B5 tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008693.1|UniProtKB=W5MQB6 W5MQB6 PTHR11861:SF10 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE PROTEIN 130 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000001455.1|UniProtKB=W5LZW0 W5LZW0 PTHR47965:SF40 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 2 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;membrane protein ectodomain proteolysis#GO:0006509;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101;Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178;Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094 LEPOC|Ensembl=ENSLOCG00000001515.1|UniProtKB=W5M041 W5M041 PTHR13280:SF16 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 LEPOC|Ensembl=ENSLOCG00000005380.1|UniProtKB=W5MDM5 W5MDM5 PTHR12642:SF0 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000000971.1|UniProtKB=W5LY78 W5LY78 PTHR13999:SF10 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008769.1|UniProtKB=W5MQL8 W5MQL8 PTHR46464:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003649.1|UniProtKB=W5M7H8 W5M7H8 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013544.1|UniProtKB=W5N7U0 W5N7U0 PTHR46812:SF1 CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG LEPOC|Ensembl=ENSLOCG00000014242.1|UniProtKB=W5NA80 W5NA80 PTHR18929:SF132 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A3 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009135.1|UniProtKB=W5MRY9 W5MRY9 PTHR46001:SF1 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM1 cytoplasm#GO:0005737;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Tiam1#P04571 LEPOC|Ensembl=ENSLOCG00000004435.1|UniProtKB=W5MA92 W5MA92 PTHR14413:SF16 RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002607.1|UniProtKB=W5M3Y2 W5M3Y2 PTHR11269:SF13 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to abiotic stimulus#GO:0009628;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01499 LEPOC|Ensembl=ENSLOCG00000009335.1|UniProtKB=W5MSM7 W5MSM7 PTHR24081:SF1 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of DNA-binding transcription factor activity#GO:0043433;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006528.1|UniProtKB=W5MHM8 W5MHM8 ABHD15 PTHR10794:SF96 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD15-LIKE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016660.1|UniProtKB=W5NIX1 W5NIX1 PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000004383.1|UniProtKB=W5MA24 W5MA24 RAMP1 PTHR14076:SF3 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;import into cell#GO:0098657 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016014.1|UniProtKB=W5NGG5 W5NGG5 PTHR31952:SF1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012030.1|UniProtKB=W5N2D9 W5N2D9 PTHR22948:SF4 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 1 negative regulation of gene expression#GO:0010629;male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;regulatory ncRNA processing#GO:0070918;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;piRNA processing#GO:0034587;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;multicellular organism development#GO:0007275;regionalization#GO:0003002;oogenesis#GO:0048477;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012363.1|UniProtKB=W5N3M2 W5N3M2 PTHR11616:SF261 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008018.1|UniProtKB=W5MMY1 W5MMY1 PTHR10654:SF15 CAS SCAFFOLDING PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 CCKR signaling map#P06959>CAS#P07180;Integrin signalling pathway#P00034>p130CAS#P00908 LEPOC|Ensembl=ENSLOCG00000016365.1|UniProtKB=W5NHU8 W5NHU8 PTHR24240:SF148 OPSIN NOVOPSIN-9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005383.1|UniProtKB=W5MDN3 W5MDN3 PTHR18916:SF44 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005033.1|UniProtKB=W5MCF2 W5MCF2 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003045.1|UniProtKB=W5M5C8 W5M5C8 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013150.1|UniProtKB=W5N6E0 W5N6E0 PTHR15627:SF8 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 LEPOC|Ensembl=ENSLOCG00000011909.1|UniProtKB=W5N1Y3 W5N1Y3 GRP PTHR16866:SF2 GASTRIN-RELEASING PEPTIDE GASTRIN-RELEASING PEPTIDE neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010732.1|UniProtKB=W5MXP0 W5MXP0 PTHR24056:SF130 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 6 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007413.1|UniProtKB=W5MKU2 W5MKU2 PTHR11824:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;neuromuscular junction development#GO:0007528;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 LEPOC|Ensembl=ENSLOCG00000017139.1|UniProtKB=W5NKM2 W5NKM2 PTHR21472:SF26 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000014170.1|UniProtKB=W5NA03 W5NA03 PTHR14149:SF15 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;calmodulin binding#GO:0005516;actin binding#GO:0003779;enzyme regulator activity#GO:0030234 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;actomyosin contractile ring assembly#GO:0000915;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;cytokinetic process#GO:0032506;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;regulation of molecular function#GO:0065009;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular component assembly#GO:0022607;epidermal growth factor receptor signaling pathway#GO:0007173;mitotic cytokinetic process#GO:1902410;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;cell division#GO:0051301;regulation of phosphate metabolic process#GO:0019220;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;mitotic cytokinesis#GO:0000281;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;signaling#GO:0023052;cytokinesis#GO:0000910;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of kinase activity#GO:0033674;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005448.1|UniProtKB=W5MDW2 W5MDW2 PTHR22998:SF1 SARM1 NAD(+) HYDROLASE SARM1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001382.1|UniProtKB=W5LZK8 W5LZK8 PTHR31051:SF1 PROTEASOME ASSEMBLY CHAPERONE 3 PROTEASOME ASSEMBLY CHAPERONE 3 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015076.1|UniProtKB=W5ND45 W5ND45 EFCAB6 PTHR20875:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000013980.1|UniProtKB=W5N9F6 W5N9F6 PTHR12658:SF0 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007040.1|UniProtKB=W5MJF8 W5MJF8 PTHR15427:SF20 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER ADIPONECTIN scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>Adiponectin#P06761 LEPOC|Ensembl=ENSLOCG00000013425.1|UniProtKB=W5N7F7 W5N7F7 PTHR12848:SF16 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 signal transduction#GO:0007165;regulation of catabolic process#GO:0009894;regulation of cellular component organization#GO:0051128;regulation of growth#GO:0040008;response to extracellular stimulus#GO:0009991;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell growth#GO:0001558;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;positive regulation of growth#GO:0045927;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011280.1|UniProtKB=W5MZQ1 W5MZQ1 PTHR24028:SF296 CADHERIN-87A PROTOCADHERIN 1 GAMMA 11 PRECURSOR-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000005097.1|UniProtKB=W5MCN0 W5MCN0 PTHR10913:SF80 FOLLISTATIN-RELATED TOMOREGULIN-2 multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000014230.1|UniProtKB=W5NA66 W5NA66 PTHR15453:SF8 TUMOR SUPPRESSOR CANDIDATE 2 TUMOR SUPPRESSOR CANDIDATE 2 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012162.1|UniProtKB=W5N2V3 W5N2V3 PTHR28556:SF6 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106A LEPOC|Ensembl=ENSLOCG00000008338.1|UniProtKB=W5MP16 W5MP16 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004522.1|UniProtKB=W5MAK1 W5MAK1 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cell cycle process#GO:0022402;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cell division#GO:0051301;cellular process#GO:0009987;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004084.1|UniProtKB=W5M920 W5M920 PTHR16052:SF0 TBCC DOMAIN-CONTAINING PROTEIN 1 TBCC DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005030.1|UniProtKB=W5MCE9 W5MCE9 HLCS PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013329.1|UniProtKB=W5N725 W5N725 PTHR45747:SF18 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;protein-containing complex binding#GO:0044877;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000000868.1|UniProtKB=W5LXW4 W5LXW4 PTHR12371:SF4 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 2 protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005685.1|UniProtKB=W5MEQ6 W5MEQ6 SRSF10 PTHR23147:SF133 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007669.1|UniProtKB=W5MLP6 W5MLP6 PTHR13864:SF25 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED PROTEIN LYL-1-LIKE ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016412.1|UniProtKB=W5NI10 W5NI10 PTHR31206:SF9 LP10445P PROTEIN FAM177B LEPOC|Ensembl=ENSLOCG00000018058.1|UniProtKB=W5NNF0 W5NNF0 PTHR37361:SF4 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015108.1|UniProtKB=W5ND86 W5ND86 FHL1 PTHR24205:SF14 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS 1 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010109.1|UniProtKB=W5MVG0 W5MVG0 PTHR18935:SF6 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811 LEPOC|Ensembl=ENSLOCG00000009878.1|UniProtKB=W5MUL7 W5MUL7 PTHR10024:SF223 SYNAPTOTAGMIN SYNAPTOTAGMIN-2 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000003258.1|UniProtKB=W5M639 W5M639 PTHR13674:SF2 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162A neuron apoptotic process#GO:0051402;cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;positive regulation of organelle organization#GO:0010638;cellular response to chemical stimulus#GO:0070887;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;positive regulation of cellular component organization#GO:0051130;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;positive regulation of biological process#GO:0048518;response to oxygen levels#GO:0070482 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000968.1|UniProtKB=W5LY77 W5LY77 PTHR43272:SF101 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE BUBBLEGUM FAMILY MEMBER 2-RELATED long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013952.1|UniProtKB=W5N9A2 W5N9A2 PTHR23220:SF21 INTEGRIN ALPHA INTEGRIN ALPHA-11 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000018083.1|UniProtKB=W5NNH5 W5NNH5 PTHR33332:SF36 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RNA-DIRECTED DNA POLYMERASE LEPOC|Ensembl=ENSLOCG00000005706.1|UniProtKB=W5MEV5 W5MEV5 PTHR22529:SF1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009101.1|UniProtKB=W5MRU0 W5MRU0 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000015185.1|UniProtKB=W5NDH6 W5NDH6 PTHR24031:SF96 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX56-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010473.1|UniProtKB=W5MWU7 W5MWU7 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013169.1|UniProtKB=W5N6G3 W5N6G3 PTHR24039:SF48 FIBRILLIN-RELATED FIBRILLIN-2 ISOFORM X1-RELATED extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000016474.1|UniProtKB=W5NI99 W5NI99 PTHR12287:SF21 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of signal transduction#GO:0009966;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001942.1|UniProtKB=W5M1J5 W5M1J5 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;ribosomal subunit export from nucleus#GO:0000054;protein-DNA complex organization#GO:0071824;organelle localization#GO:0051640;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;ribosomal large subunit biogenesis#GO:0042273;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;regulation of centrosome duplication#GO:0010824;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of centrosome cycle#GO:0046605;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nuclear export#GO:0051168;protein-containing complex organization#GO:0043933;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;chromatin organization#GO:0006325;intracellular transport#GO:0046907;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;ribosomal small subunit biogenesis#GO:0042274;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002617.1|UniProtKB=W5M3X0 W5M3X0 PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017176.1|UniProtKB=W5NKS0 W5NKS0 KCNK16 PTHR11003:SF104 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 16 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015445.1|UniProtKB=W5NEF8 W5NEF8 PTHR45817:SF1 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015852.1|UniProtKB=W5NFV8 W5NFV8 PTHR11915:SF449 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN PH DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000004813.1|UniProtKB=W5MBM1 W5MBM1 PTHR24161:SF21 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 35 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005028.1|UniProtKB=W5MCE7 W5MCE7 PDE1B PTHR11347:SF194 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;cellular anatomical entity#GO:0110165;cell body#GO:0044297;neuronal cell body#GO:0043025 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000007699.1|UniProtKB=W5MLU0 W5MLU0 PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000007194.1|UniProtKB=W5MJZ7 W5MJZ7 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 localization within membrane#GO:0051668;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;post-translational protein targeting to membrane, translocation#GO:0031204;protein localization to membrane#GO:0072657;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003819.1|UniProtKB=W5M852 W5M852 PTHR12259:SF3 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017708.1|UniProtKB=W5NMF4 W5NMF4 PTHR10155:SF35 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 4 ISOFORM X1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000010864.1|UniProtKB=W5MY74 W5MY74 TENM2 PTHR11219:SF8 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-2 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000002322.1|UniProtKB=W5M2Y6 W5M2Y6 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000008.1|UniProtKB=W5LV50 W5LV50 PTHR19282:SF40 TETRASPANIN TETRASPANIN-4 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016321.1|UniProtKB=W5NHP0 W5NHP0 PTHR24115:SF734 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3C pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007361.1|UniProtKB=W5MKK8 W5MKK8 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006625.1|UniProtKB=W5MHZ0 W5MHZ0 PTHR36292:SF1 UPF0575 PROTEIN C19ORF67 UPF0575 PROTEIN C19ORF67 LEPOC|Ensembl=ENSLOCG00000016309.1|UniProtKB=W5NHM1 W5NHM1 PTHR24034:SF207 EGF-LIKE DOMAIN-CONTAINING PROTEIN CD248 MOLECULE extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000012623.1|UniProtKB=W5N4I1 W5N4I1 PTHR12873:SF0 T7-LIKE MITOCHONDRIAL DNA HELICASE TWINKLE MTDNA HELICASE ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003547.1|UniProtKB=W5M735 W5M735 PTHR24023:SF914 COLLAGEN ALPHA OTOLIN-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000007619.1|UniProtKB=W5MLI4 W5MLI4 PTHR47305:SF1 BEN DOMAIN-CONTAINING PROTEIN 2 BEN DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013763.1|UniProtKB=W5N8L6 W5N8L6 PTHR18945:SF216 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016703.1|UniProtKB=W5NJ25 W5NJ25 PTHR24060:SF160 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000008483.1|UniProtKB=W5MPM3 W5MPM3 PTHR11731:SF202 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003103.1|UniProtKB=W5M5J5 W5M5J5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002502.1|UniProtKB=W5M3I3 W5M3I3 PTHR11348:SF33 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CELLULAR COMMUNICATION NETWORK FACTOR 1, LIKE 1 PRECURSOR-RELATED carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cell adhesion#GO:0007155;cell communication#GO:0007154;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;signaling#GO:0023052 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000008239.1|UniProtKB=W5MNP3 W5MNP3 PTHR22930:SF258 FAMILY NOT NAMED PROTEIN ALP1-LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000001122.1|UniProtKB=W5LYR4 W5LYR4 PTHR23193:SF5 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121C-RELATED signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006422.1|UniProtKB=W5MHA1 W5MHA1 PTHR24369:SF196 ANTIGEN BSP, PUTATIVE-RELATED RETICULON 4 RECEPTOR LIKE 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005745.1|UniProtKB=W5MEX9 W5MEX9 PTHR11471:SF54 TUMOR NECROSIS FACTOR FAMILY MEMBER TNF SUPERFAMILY MEMBER 11 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000017910.1|UniProtKB=W5NN04 W5NN04 PTHR11537:SF250 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 5 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cation channel complex#GO:0034703;intercalated disc#GO:0014704;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;cell-cell contact zone#GO:0044291;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000001784.1|UniProtKB=W5M130 W5M130 PTHR11947:SF21 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 3, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003128.1|UniProtKB=W5M5Q9 W5M5Q9 PTHR10766:SF111 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017905.1|UniProtKB=W5NMZ9 W5NMZ9 TMEM229A PTHR31746:SF2 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229A LEPOC|Ensembl=ENSLOCG00000016243.1|UniProtKB=W5NHB9 W5NHB9 HMGN3 PTHR23087:SF2 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 3 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011080.1|UniProtKB=W5MYZ2 W5MYZ2 PTHR31020:SF1 TRANSMEMBRANE PROTEIN 174 TRANSMEMBRANE PROTEIN 174 LEPOC|Ensembl=ENSLOCG00000008725.1|UniProtKB=W5MQG2 W5MQG2 PTHR10217:SF506 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of heart contraction#GO:0008016;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;regulation of system process#GO:0044057;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001889.1|UniProtKB=W5M1D6 W5M1D6 NT5M PTHR16504:SF4 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 LEPOC|Ensembl=ENSLOCG00000015922.1|UniProtKB=W5NG46 W5NG46 PTHR21663:SF2 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012819.1|UniProtKB=W5N571 W5N571 PTHR13055:SF10 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017322.1|UniProtKB=W5NLB8 W5NLB8 PTHR10704:SF36 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;aminoglycan metabolic process#GO:0006022;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005550.1|UniProtKB=W5MEB0 W5MEB0 PTHR19375:SF379 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 LEPOC|Ensembl=ENSLOCG00000001508.1|UniProtKB=W5M010 W5M010 PTHR14845:SF0 COILED-COIL DOMAIN-CONTAINING 166 DUF4515 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007472.1|UniProtKB=W5ML09 W5ML09 PTHR22739:SF21 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001802.1|UniProtKB=W5M1D4 W5M1D4 PTHR14017:SF9 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 6A cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;binding#GO:0005488;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;double-stranded DNA binding#GO:0003690;oxidoreductase activity#GO:0016491;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;demethylase activity#GO:0032451;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;dioxygenase activity#GO:0051213;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004317.1|UniProtKB=W5M9U5 W5M9U5 PTHR21737:SF21 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 MARVEL DOMAIN CONTAINING 3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014550.1|UniProtKB=W5NB97 W5NB97 PTHR34921:SF1 MEIOTIC RECOMBINATION PROTEIN REC114 MEIOTIC RECOMBINATION PROTEIN REC114 LEPOC|Ensembl=ENSLOCG00000014294.1|UniProtKB=W5NAD8 W5NAD8 PTHR18945:SF831 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-3 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotine pharmacodynamics pathway#P06587>CHRNA3#P06595;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000000855.1|UniProtKB=W5LXU7 W5LXU7 PTHR12002:SF108 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000006505.1|UniProtKB=W5MHK0 W5MHK0 PTHR10344:SF1 THYMIDYLATE KINASE THYMIDYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 LEPOC|Ensembl=ENSLOCG00000010366.1|UniProtKB=W5MWE1 W5MWE1 TMEM272 PTHR33444:SF7 SI:DKEY-19B23.12-RELATED TRANSMEMBRANE PROTEIN 272 LEPOC|Ensembl=ENSLOCG00000012769.1|UniProtKB=W5N504 W5N504 PTHR12598:SF0 COPPER HOMEOSTASIS PROTEIN CUTC COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010611.1|UniProtKB=W5MX96 W5MX96 PTHR13723:SF27 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010875.1|UniProtKB=W5MY78 W5MY78 PTHR44117:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;ciliary base#GO:0097546;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000005257.1|UniProtKB=W5MD70 W5MD70 PTHR24208:SF80 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>LHX2#P06756 LEPOC|Ensembl=ENSLOCG00000016185.1|UniProtKB=W5NH42 W5NH42 PTHR23197:SF8 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007656.1|UniProtKB=W5MLM6 W5MLM6 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554 LEPOC|Ensembl=ENSLOCG00000017715.1|UniProtKB=W5NMG1 W5NMG1 PTHR24234:SF7 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 132-RELATED negative regulation of biological process#GO:0048519;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle phase transition#GO:0044772;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;negative regulation of cell cycle process#GO:0010948;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006511.1|UniProtKB=W5MHM5 W5MHM5 PTHR11904:SF26 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009147.1|UniProtKB=W5MS07 W5MS07 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000006755.1|UniProtKB=W5MIF7 W5MIF7 PTHR11473:SF23 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 LEPOC|Ensembl=ENSLOCG00000006945.1|UniProtKB=W5MJ41 W5MJ41 PTHR12015:SF190 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011470.1|UniProtKB=W5N0C8 W5N0C8 PTHR15863:SF2 MRN COMPLEX-INTERACTING PROTEIN MRN COMPLEX-INTERACTING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;mitotic DNA damage checkpoint signaling#GO:0044773 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000707.1|UniProtKB=W5LXC8 W5LXC8 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009749.1|UniProtKB=W5MU54 W5MU54 SEL1L3 PTHR44444:SF1 PROTEIN SEL-1 HOMOLOG 3 PROTEIN SEL-1 HOMOLOG 3 LEPOC|Ensembl=ENSLOCG00000012991.1|UniProtKB=W5N5V1 W5N5V1 PTHR24213:SF18 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;actomyosin#GO:0042641;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Axon guidance mediated by netrin#P00009>Ablim#P00358 LEPOC|Ensembl=ENSLOCG00000016473.1|UniProtKB=W5NI92 W5NI92 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000006509.1|UniProtKB=W5MHL3 W5MHL3 PTHR24255:SF10 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005136.1|UniProtKB=W5MCS7 W5MCS7 PTHR28556:SF5 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106C LEPOC|Ensembl=ENSLOCG00000013167.1|UniProtKB=W5N6F9 W5N6F9 PTHR11691:SF62 TYPE I INTERFERON INTERFERON PHI 2-RELATED cytokine#PC00083;interferon superfamily#PC00127 LEPOC|Ensembl=ENSLOCG00000005076.1|UniProtKB=W5MCK3 W5MCK3 PTHR45722:SF2 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013702.1|UniProtKB=W5N8D9 W5N8D9 PTHR46179:SF5 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZXDC molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015889.1|UniProtKB=W5NG07 W5NG07 PTHR14582:SF1 INNER KINETOCHORE SUBUNIT MAL2 CENTROMERE PROTEIN O supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005264.1|UniProtKB=W5MD81 W5MD81 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009234.1|UniProtKB=W5MSA3 W5MSA3 PTHR12707:SF0 PINN PININ ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012651.1|UniProtKB=W5N4L0 W5N4L0 PTHR11476:SF7 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016864.1|UniProtKB=W5NJN7 W5NJN7 PTHR22968:SF26 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 LEPOC|Ensembl=ENSLOCG00000011083.1|UniProtKB=W5MYZ9 W5MYZ9 PTHR14255:SF4 CEREBLON PROTEIN CEREBLON protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002508.1|UniProtKB=W5M3K2 W5M3K2 PTHR31488:SF1 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L1 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008544.1|UniProtKB=W5MPT7 W5MPT7 PTHR14950:SF37 DICER-RELATED ENDORIBONUCLEASE DICER LEPOC|Ensembl=ENSLOCG00000017261.1|UniProtKB=W5NL40 W5NL40 PTHR48134:SF2 GLYCOPROTEIN 96-92-RELATED-RELATED OS04G0609100 PROTEIN LEPOC|Ensembl=ENSLOCG00000012402.1|UniProtKB=W5N3R6 W5N3R6 PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003472.1|UniProtKB=W5M6X1 W5M6X1 PTHR13083:SF3 WD REPEAT-CONTAINING PROTEIN 91 WD REPEAT-CONTAINING PROTEIN 91 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000016987.1|UniProtKB=W5NK38 W5NK38 FYN PTHR24418:SF44 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FYN protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;activation of immune response#GO:0002253;developmental process#GO:0032502;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Parkinson disease#P00049>Src kinase#P01230;Cadherin signaling pathway#P00012>Fyn#P00464;Parkinson disease#P00049>Fyn kinase#P01235;Integrin signalling pathway#P00034>Fyn#P00942 LEPOC|Ensembl=ENSLOCG00000017808.1|UniProtKB=W5NMQ3 W5NMQ3 PTHR46473:SF23 GH08155P GH08155P LEPOC|Ensembl=ENSLOCG00000012986.1|UniProtKB=W5N5T7 W5N5T7 PTHR10488:SF1 GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013070.1|UniProtKB=W5N651 W5N651 SPPL2A PTHR12174:SF34 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2A hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;Golgi-associated vesicle membrane#GO:0030660;endoplasmic reticulum subcompartment#GO:0098827;lysosome#GO:0005764;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009291.1|UniProtKB=W5MSI3 W5MSI3 PTHR23069:SF4 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;nucleosome assembly#GO:0006334;RNA metabolic process#GO:0016070;positive regulation of cellular metabolic process#GO:0031325;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;protein-containing complex disassembly#GO:0032984;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;epigenetic regulation of gene expression#GO:0040029;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010712.1|UniProtKB=W5MXL1 W5MXL1 SCD5 PTHR11351:SF100 ACYL-COA DESATURASE STEAROYL-COA DESATURASE 5 cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007426.1|UniProtKB=W5MKV9 W5MKV9 PTHR13347:SF1 HEAT REPEAT-CONTAINING PROTEIN 3 HEAT REPEAT-CONTAINING PROTEIN 3 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;ribosome biogenesis#GO:0042254;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 LEPOC|Ensembl=ENSLOCG00000007685.1|UniProtKB=W5MLS1 W5MLS1 PTHR11829:SF406 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000013922.1|UniProtKB=W5N962 W5N962 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;inorganic anion transmembrane transporter activity#GO:0015103;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 succinate transport#GO:0015744;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;inorganic anion transmembrane transport#GO:0098661;localization#GO:0051179;organic substance transport#GO:0071702;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825;inorganic anion transport#GO:0015698 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014764.1|UniProtKB=W5NC26 W5NC26 PTHR13720:SF22 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007301.1|UniProtKB=W5MKD2 W5MKD2 PTHR34072:SF52 ENZYMATIC POLYPROTEIN-RELATED RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000006333.1|UniProtKB=W5MGY8 W5MGY8 PTHR19960:SF7 TEKTIN TEKTIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012249.1|UniProtKB=W5N363 W5N363 PTHR10910:SF17 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2 nucleic acid binding#GO:0003676;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;RNA binding#GO:0003723;tRNA-specific adenosine deaminase activity#GO:0008251;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;adenosine to inosine editing#GO:0006382;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015535.1|UniProtKB=W5NER2 W5NER2 PTHR45636:SF47 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008035.1|UniProtKB=W5MN01 W5MN01 PTHR13869:SF21 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 2 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016276.1|UniProtKB=W5NHH0 W5NHH0 PTHR15036:SF51 PIKACHURIN-LIKE PROTEIN NEUREXIN-1 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002697.1|UniProtKB=W5M476 W5M476 PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006064.1|UniProtKB=W5MG10 W5MG10 PTHR22168:SF7 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26-LIKE LEPOC|Ensembl=ENSLOCG00000010021.1|UniProtKB=W5MV46 W5MV46 PTHR13218:SF8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000014426.1|UniProtKB=W5NAV1 W5NAV1 PTHR24006:SF860 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN SPECIFIC PEPTIDASE 12-LIKE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009412.1|UniProtKB=W5MSX9 W5MSX9 PTHR23086:SF34 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000007549.1|UniProtKB=W5MLA3 W5MLA3 PTHR15046:SF1 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN BETA-1,4 N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000014510.1|UniProtKB=W5NB61 W5NB61 PTHR18978:SF1 GRIP-1 ASSOCIATED PROTEIN 1 GRIP1-ASSOCIATED PROTEIN 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of synapse organization#GO:0050807;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;regulation of protein transport#GO:0051223;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;vesicle-mediated transport#GO:0016192;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of synapse structure or activity#GO:0050803;regulation of establishment of protein localization#GO:0070201;protein-containing complex localization#GO:0031503 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;early endosome#GO:0005769;glutamatergic synapse#GO:0098978;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;postsynapse#GO:0098794;cytoplasmic vesicle membrane#GO:0030659 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000004641.1|UniProtKB=W5MB02 W5MB02 PTHR21094:SF2 GOS-28 SNARE- RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;SNARE complex#GO:0031201;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000000247.1|UniProtKB=W5LVY2 W5LVY2 PTHR11461:SF53 SERINE PROTEASE INHIBITOR, SERPIN ANTITHROMBIN-III extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>ATIII#P00440 LEPOC|Ensembl=ENSLOCG00000011520.1|UniProtKB=W5N0J7 W5N0J7 PTHR10900:SF82 PERIOSTIN-RELATED TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004542.1|UniProtKB=W5MAM3 W5MAM3 GPR55 PTHR24232:SF56 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 55 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000800.1|UniProtKB=W5LXM9 W5LXM9 PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011576.1|UniProtKB=W5N0R3 W5N0R3 PTHR24412:SF435 KELCH PROTEIN KELCH-LIKE PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009014.1|UniProtKB=W5MRH6 W5MRH6 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005323.1|UniProtKB=W5MDF0 W5MDF0 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003917.1|UniProtKB=W5M8H0 W5M8H0 PTHR11848:SF157 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 2 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000005389.1|UniProtKB=W5MDN8 W5MDN8 PTHR13299:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX16 PEROXISOMAL MEMBRANE PROTEIN PEX16 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;peroxisome organization#GO:0007031 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012392.1|UniProtKB=W5N3Q1 W5N3Q1 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002813.1|UniProtKB=W5M4K1 W5M4K1 PTHR23255:SF51 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 heart development#GO:0007507;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 LEPOC|Ensembl=ENSLOCG00000013380.1|UniProtKB=W5N785 W5N785 PTHR24211:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM AND CYSTEINE-RICH DOMAINS PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006174.1|UniProtKB=W5MGE9 W5MGE9 PTHR19960:SF11 TEKTIN TEKTIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010994.1|UniProtKB=W5MYM7 W5MYM7 PTHR10605:SF30 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011283.1|UniProtKB=W5MZR1 W5MZR1 PTHR28384:SF1 PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002141.1|UniProtKB=W5M282 W5M282 PTHR48023:SF7 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 10 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;system development#GO:0048731;circulatory system development#GO:0072359;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002987.1|UniProtKB=W5M558 W5M558 PTHR11818:SF13 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B3 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009868.1|UniProtKB=W5MUK0 W5MUK0 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000001308.1|UniProtKB=W5LZD2 W5LZD2 PTHR45848:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000009606.1|UniProtKB=W5MTN7 W5MTN7 PTHR46606:SF3 SHOOTIN-1 SHOOTIN-1 neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cell leading edge#GO:0031252;cytoplasm#GO:0005737;axonal growth cone#GO:0044295;neuron projection#GO:0043005;distal axon#GO:0150034;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010185.1|UniProtKB=W5MVQ9 W5MVQ9 PTHR11860:SF118 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003952.1|UniProtKB=W5M8L0 W5M8L0 ELOVL1 PTHR11157:SF19 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000016326.1|UniProtKB=W5NHP8 W5NHP8 PTHR11109:SF6 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 LEPOC|Ensembl=ENSLOCG00000009936.1|UniProtKB=W5MUU1 W5MUU1 PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000784.1|UniProtKB=W5LXL2 W5LXL2 PTHR45134:SF5 OS08G0543275 PROTEIN OS08G0543275 PROTEIN LEPOC|Ensembl=ENSLOCG00000012974.1|UniProtKB=W5N5U3 W5N5U3 PTHR22605:SF21 RZ-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF213-BETA transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;sprouting angiogenesis#GO:0002040;vasculature development#GO:0001944;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;circulatory system development#GO:0072359;negative regulation of response to stimulus#GO:0048585;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;tube development#GO:0035295;organonitrogen compound metabolic process#GO:1901564;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000013854.1|UniProtKB=W5N8X8 W5N8X8 PTHR13220:SF11 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;intracellular signal transduction#GO:0035556;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016471.1|UniProtKB=W5NI87 W5NI87 EML4 PTHR13720:SF11 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009678.1|UniProtKB=W5MTX6 W5MTX6 PTHR10502:SF17 ANNEXIN ANNEXIN A1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;phagocytosis#GO:0006909;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;import into cell#GO:0098657;signaling#GO:0023052;response to steroid hormone#GO:0048545 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000009422.1|UniProtKB=W5MSY9 W5MSY9 PTHR16821:SF2 FRATAXIN FRATAXIN, MITOCHONDRIAL transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003251.1|UniProtKB=W5M631 W5M631 HASPIN PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN histone modifying activity#GO:0140993;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004826.1|UniProtKB=W5MBN4 W5MBN4 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004447.1|UniProtKB=W5MA99 W5MA99 PTHR24247:SF107 5-HYDROXYTRYPTAMINE RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 13C-LIKE cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012505.1|UniProtKB=W5N449 W5N449 PTHR24270:SF16 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VERY LOW-DENSITY LIPOPROTEIN RECEPTOR protein binding#GO:0005515;binding#GO:0005488 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000004365.1|UniProtKB=W5MA04 W5MA04 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013250.1|UniProtKB=W5N6R3 W5N6R3 PTHR24234:SF9 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 132-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005970.1|UniProtKB=W5MFQ5 W5MFQ5 PTHR16234:SF5 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20508 AFG2-INTERACTING RIBOSOME MATURATION FACTOR cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017736.1|UniProtKB=W5NMI1 W5NMI1 PTHR23226:SF248 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 648 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007427.1|UniProtKB=W5MKV1 W5MKV1 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014157.1|UniProtKB=W5N9Y1 W5N9Y1 IL17RB PTHR15583:SF11 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR B signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003161.1|UniProtKB=W5M5S5 W5M5S5 LRRC19 PTHR24366:SF171 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT NEURONAL 4 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000010696.1|UniProtKB=W5MXJ0 W5MXJ0 PTHR14971:SF2 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000883.1|UniProtKB=W5LXY0 W5LXY0 PTHR18949:SF0 CALDESMON CALDESMON cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;developmental process#GO:0032502;multicellular organism development#GO:0007275;actin filament bundle assembly#GO:0051017;tube development#GO:0035295;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;organelle organization#GO:0006996;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011526.1|UniProtKB=W5N0K1 W5N0K1 PTHR12378:SF7 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015253.1|UniProtKB=W5NDR0 W5NDR0 PTHR11932:SF66 CULLIN CULLIN-4B enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000946.1|UniProtKB=W5LY45 W5LY45 PTHR24246:SF18 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;system process#GO:0003008;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000014891.1|UniProtKB=W5NCH8 W5NCH8 PTHR24409:SF315 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 711 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003098.1|UniProtKB=W5M5K5 W5M5K5 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000016078.1|UniProtKB=W5NGQ1 W5NGQ1 PTHR15840:SF10 CGI-121 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT TPRKB cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA threonylcarbamoyladenosine metabolic process#GO:0070525;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004213.1|UniProtKB=W5M9H6 W5M9H6 PTHR28616:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;negative regulation of response to stimulus#GO:0048585;regulation of locomotion#GO:0040012;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of small GTPase mediated signal transduction#GO:0051058;negative regulation of signal transduction#GO:0009968;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018276.1|UniProtKB=W5NP18 W5NP18 PTHR17045:SF5 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 4 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000013361.1|UniProtKB=W5N761 W5N761 PTHR24251:SF24 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 1 peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;collagen binding#GO:0005518;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010549.1|UniProtKB=W5MX20 W5MX20 PTHR22767:SF6 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 15, NATA AUXILIARY SUBUNIT macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000010556.1|UniProtKB=W5MX36 W5MX36 PTHR16062:SF19 SWI/SNF-RELATED PROTEIN POLYBROMO-1 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;transcription elongation by RNA polymerase II#GO:0006368;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009786.1|UniProtKB=W5MU97 W5MU97 PTHR14198:SF22 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 19 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013028.1|UniProtKB=W5N5Z0 W5N5Z0 PTHR21646:SF27 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010180.1|UniProtKB=W5MVQ5 W5MVQ5 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL nucleotide binding#GO:0000166;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016360.1|UniProtKB=W5NHV2 W5NHV2 SRBD1 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007779.1|UniProtKB=W5MM51 W5MM51 PTHR22974:SF22 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;chromosome segregation#GO:0007059;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004585.1|UniProtKB=W5MAU7 W5MAU7 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000015964.1|UniProtKB=W5NG99 W5NG99 PTHR13006:SF6 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 395 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012960.1|UniProtKB=W5N5Q6 W5N5Q6 PTHR11461:SF204 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B6 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000001189.1|UniProtKB=W5LYZ3 W5LYZ3 PTHR13723:SF159 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PLAC DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012515.1|UniProtKB=W5N450 W5N450 PTHR23055:SF30 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 4 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009844.1|UniProtKB=W5MUH4 W5MUH4 PTHR16166:SF22 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13A cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein localization to Golgi apparatus#GO:0034067;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;protein transport#GO:0015031;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007044.1|UniProtKB=W5MJG5 W5MJG5 PTHR22802:SF404 C-TYPE LECTIN SUPERFAMILY MEMBER SI:DKEY-9I23.4-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016869.1|UniProtKB=W5NJQ0 W5NJQ0 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000010657.1|UniProtKB=W5MXE7 W5MXE7 PTHR24114:SF49 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A LEPOC|Ensembl=ENSLOCG00000010188.1|UniProtKB=W5MVR4 W5MVR4 PTHR24353:SF37 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Endothelin signaling pathway#P00019>PKG#P00567;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 LEPOC|Ensembl=ENSLOCG00000008919.1|UniProtKB=W5MR51 W5MR51 DCDC2 PTHR23004:SF5 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2 cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of plasma membrane bounded cell projection assembly#GO:0120032;dendrite development#GO:0016358;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of cilium assembly#GO:1902017;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;dendrite morphogenesis#GO:0048813;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;neuron migration#GO:0001764;regulation of cell projection assembly#GO:0060491;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;plasma membrane bounded cell projection assembly#GO:0120031;cell migration#GO:0016477 supramolecular complex#GO:0099080;axoneme#GO:0005930;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;kinocilium#GO:0060091;stereocilium bundle#GO:0032421;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000013914.1|UniProtKB=W5N944 W5N944 PTHR14465:SF0 IQ DOMAIN-CONTAINING PROTEIN H IQ DOMAIN-CONTAINING PROTEIN H LEPOC|Ensembl=ENSLOCG00000013074.1|UniProtKB=W5N644 W5N644 PTHR24366:SF158 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS PLATELET GLYCOPROTEIN IB ALPHA CHAIN-LIKE-RELATED cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015289.1|UniProtKB=W5NDV2 W5NDV2 PTHR12837:SF9 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;regulation of DNA repair#GO:0006282;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;purine ribonucleoside triphosphate metabolic process#GO:0009205;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008160.1|UniProtKB=W5MNG9 W5MNG9 PTHR18966:SF99 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 2 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu2#P01017;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 LEPOC|Ensembl=ENSLOCG00000014488.1|UniProtKB=W5NB27 W5NB27 PTHR15108:SF0 N-ACYLGLUCOSAMINE-2-EPIMERASE N-ACYLGLUCOSAMINE 2-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003806.1|UniProtKB=W5M831 W5M831 PTHR12297:SF3 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009352.1|UniProtKB=W5MSP8 W5MSP8 PTHR24248:SF21 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-2 ADRENERGIC RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of blood pressure#GO:0045776;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of systemic arterial blood pressure#GO:0003073;cellular process#GO:0009987;circulatory system process#GO:0003013;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of blood pressure#GO:0008217;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Beta2 adrenergic receptor signaling pathway#P04378>Beta2#P04440;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000013668.1|UniProtKB=W5N890 W5N890 FAM81A PTHR22420:SF2 PROTEIN FAM81A PROTEIN FAM81A LEPOC|Ensembl=ENSLOCG00000010106.1|UniProtKB=W5MVH4 W5MVH4 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA splice site recognition#GO:0006376;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016559.1|UniProtKB=W5NIJ1 W5NIJ1 PTHR12917:SF17 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 2 aspartic protease#PC00053;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000274.1|UniProtKB=W5LVZ2 W5LVZ2 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005092.1|UniProtKB=W5MCM4 W5MCM4 CLDN16 PTHR12002:SF56 CLAUDIN CLAUDIN-16 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000008119.1|UniProtKB=W5MNA0 W5MNA0 PTHR13385:SF0 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007621.1|UniProtKB=W5MLI7 W5MLI7 PTHR43330:SF8 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloaminopeptidase activity#GO:0070006 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008136.1|UniProtKB=W5MNB9 W5MNB9 PTHR24412:SF492 KELCH PROTEIN KELCH-LIKE PROTEIN 20 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007441.1|UniProtKB=W5MKW6 W5MKW6 LRRC27 PTHR16083:SF9 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PML body#GO:0016605 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017752.1|UniProtKB=W5NMJ7 W5NMJ7 TMEM100 PTHR16100:SF5 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER TRANSMEMBRANE PROTEIN 100 cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;response to BMP#GO:0071772;response to endogenous stimulus#GO:0009719;cellular response to endogenous stimulus#GO:0071495;cellular response to growth factor stimulus#GO:0071363;response to growth factor#GO:0070848 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005627.1|UniProtKB=W5MEI3 W5MEI3 PTHR21191:SF8 AQUAPORIN AQUAPORIN-12A-RELATED passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007476.1|UniProtKB=W5ML13 W5ML13 PTHR24243:SF7 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008413.1|UniProtKB=W5MPB9 W5MPB9 PTHR18063:SF7 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein K48-linked deubiquitination#GO:0071108;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015173.1|UniProtKB=W5NDG3 W5NDG3 PTHR13015:SF0 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003053.1|UniProtKB=W5M5F0 W5M5F0 PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000000299.1|UniProtKB=W5LW19 W5LW19 PTHR43178:SF5 DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL fatty acid binding#GO:0005504;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002492.1|UniProtKB=W5M3G7 W5M3G7 PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016249.1|UniProtKB=W5NHD0 W5NHD0 PTHR11473:SF16 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 LEPOC|Ensembl=ENSLOCG00000018060.1|UniProtKB=W5NNF2 W5NNF2 PTHR11937:SF574 ACTIN ACTIN-LIKE PROTEIN ARP9 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000011796.1|UniProtKB=W5N1L2 W5N1L2 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000011013.1|UniProtKB=W5MYQ5 W5MYQ5 RSBN1 PTHR13354:SF8 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE 9 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005717.1|UniProtKB=W5MEW0 W5MEW0 PTHR43084:SF1 PERSULFIDE DIOXYGENASE ETHE1 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018087.1|UniProtKB=W5NNH9 W5NNH9 PTGDR2 PTHR24225:SF50 CHEMOTACTIC RECEPTOR PROSTAGLANDIN D2 RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005009.1|UniProtKB=W5MCC0 W5MCC0 PTHR16770:SF4 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY3 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003170.1|UniProtKB=W5M5U1 W5M5U1 CIAPIN1 PTHR13273:SF14 ANAMORSIN ANAMORSIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003044.1|UniProtKB=W5M5H3 W5M5H3 PTHR10663:SF124 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010358.1|UniProtKB=W5MWD8 W5MWD8 PTHR24064:SF682 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 5 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005663.1|UniProtKB=W5MEN5 W5MEN5 PTHR12934:SF11 50S RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009515.1|UniProtKB=W5MTF8 W5MTF8 PTHR13817:SF52 TITIN ROUNDABOUT GUIDANCE RECEPTOR 1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017207.1|UniProtKB=W5NKW5 W5NKW5 PTHR23339:SF26 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017784.1|UniProtKB=W5NMM9 W5NMM9 PTHR24231:SF15 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 2-OXOGLUTARATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007362.1|UniProtKB=W5MKL5 W5MKL5 PTHR12622:SF35 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011805.1|UniProtKB=W5N1K8 W5N1K8 MICALL1 PTHR23167:SF89 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000011721.1|UniProtKB=W5N195 W5N195 PTHR16209:SF4 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN 1-LIKE LEPOC|Ensembl=ENSLOCG00000016926.1|UniProtKB=W5NJW4 W5NJW4 PTHR21442:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000017264.1|UniProtKB=W5NL45 W5NL45 PTHR11685:SF225 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF217 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014055.1|UniProtKB=W5N9M5 W5N9M5 PTHR13260:SF0 ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4 ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear periphery#GO:0034399;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010903.1|UniProtKB=W5MYA8 W5MYA8 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003327.1|UniProtKB=W5M6F4 W5M6F4 PTHR45656:SF15 PROTEIN CBR-CLEC-78 SUSHI DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014574.1|UniProtKB=W5NBC4 W5NBC4 PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000412.1|UniProtKB=W5LWE3 W5LWE3 PTHR11977:SF33 VILLIN ADVILLIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012714.1|UniProtKB=W5N4T4 W5N4T4 PTHR15528:SF5 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-RELATED PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004426.1|UniProtKB=W5MA83 W5MA83 TMPRSS7 PTHR24253:SF103 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 7 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005425.1|UniProtKB=W5MDT7 W5MDT7 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016695.1|UniProtKB=W5NJ18 W5NJ18 PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000008777.1|UniProtKB=W5MQM7 W5MQM7 PTHR10239:SF28 ISTHMIN-2 ISTHMIN-2 LEPOC|Ensembl=ENSLOCG00000014091.1|UniProtKB=W5N9Q8 W5N9Q8 PTHR42884:SF8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 6 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;extracellular matrix#GO:0031012;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell surface#GO:0009986;external encapsulating structure#GO:0030312;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;collagen-containing extracellular matrix#GO:0062023;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000008911.1|UniProtKB=W5MR44 W5MR44 PTHR22870:SF335 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN CONTAINING PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017377.1|UniProtKB=W5NLH3 W5NLH3 PTHR24231:SF2 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;G protein-coupled receptor activity#GO:0004930;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002218.1|UniProtKB=W5M2H4 W5M2H4 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010808.1|UniProtKB=W5MXY7 W5MXY7 PTHR15077:SF10 FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD FAS-ASSOCIATED DEATH DOMAIN PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;positive regulation of response to stimulus#GO:0048584;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of defense response#GO:0031347;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of immune system process#GO:0002682;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of biological process#GO:0048518;signaling#GO:0023052 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 FAS signaling pathway#P00020>FADD#P00622;Apoptosis signaling pathway#P00006>FADD#P00327 LEPOC|Ensembl=ENSLOCG00000001288.1|UniProtKB=W5LZB8 W5LZB8 PTHR24346:SF38 MAP/MICROTUBULE AFFINITY-REGULATING KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007414.1|UniProtKB=W5MKT3 W5MKT3 PTHR23235:SF3 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CCKR signaling map#P06959>SP3#P07041 LEPOC|Ensembl=ENSLOCG00000006122.1|UniProtKB=W5MG91 W5MG91 PTHR23357:SF1 RENALASE RENALASE oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000011149.1|UniProtKB=W5MZ86 W5MZ86 PTHR23065:SF9 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017770.1|UniProtKB=W5NML5 W5NML5 PTHR24233:SF1 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 34-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015645.1|UniProtKB=W5NF51 W5NF51 PTHR24248:SF130 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2B ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000016918.1|UniProtKB=W5NJW7 W5NJW7 PTHR24023:SF917 COLLAGEN ALPHA COLLAGEN TYPE VI ALPHA 1 CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000009431.1|UniProtKB=W5MT12 W5MT12 PTHR13865:SF26 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cellular localization#GO:0051641;macromolecule localization#GO:0033036;epithelium development#GO:0060429;system process#GO:0003008;developmental process#GO:0032502;cell differentiation#GO:0030154;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;anatomical structure homeostasis#GO:0060249;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;homeostatic process#GO:0042592;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;circulatory system process#GO:0003013;protein localization#GO:0008104;cell development#GO:0048468;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446 anchoring junction#GO:0070161;tight junction#GO:0070160;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000004989.1|UniProtKB=W5MC99 W5MC99 SPATA48 PTHR34759:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 LEPOC|Ensembl=ENSLOCG00000015937.1|UniProtKB=W5NG63 W5NG63 PTHR24240:SF2 OPSIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007877.1|UniProtKB=W5MMF5 W5MMF5 PTHR12375:SF48 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 1 ISOFORM X1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000012252.1|UniProtKB=W5N369 W5N369 PTHR48482:SF5 INTERLEUKIN-19-RELATED INTERLEUKIN-10 Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000006837.1|UniProtKB=W5MIQ9 W5MIQ9 PTHR23359:SF58 NUCLEOTIDE KINASE ADENYLATE KINASE 4, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleoside diphosphate kinase activity#GO:0004550;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000017874.1|UniProtKB=W5NMW8 W5NMW8 PTHR15462:SF17 SERINE PROTEASE INACTIVE SERINE PROTEASE 35 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011869.1|UniProtKB=W5N1T3 W5N1T3 PTHR12044:SF14 BCL2 INTERACTING MEDIATOR OF CELL DEATH MEIOTIC DOUBLE-STRANDED BREAK FORMATION PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000013587.1|UniProtKB=W5N7Z4 W5N7Z4 PTHR10663:SF372 GUANYL-NUCLEOTIDE EXCHANGE FACTOR F-BOX ONLY PROTEIN 8 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009714.1|UniProtKB=W5MU01 W5MU01 PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A LEPOC|Ensembl=ENSLOCG00000017086.1|UniProtKB=W5NKF6 W5NKF6 PTHR10026:SF7 CYCLIN CYCLIN-C protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000008691.1|UniProtKB=W5MQB4 W5MQB4 PTHR15813:SF10 SORTING NEXIN-22 AND 24 SORTING NEXIN-24 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010818.1|UniProtKB=W5MY01 W5MY01 PTHR24028:SF123 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 4 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000003930.1|UniProtKB=W5M8I9 W5M8I9 PTHR11675:SF37 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 18 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008966.1|UniProtKB=W5MRD1 W5MRD1 SMARCA5 PTHR10799:SF997 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000009966.1|UniProtKB=W5MUX8 W5MUX8 PTHR13864:SF27 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012326.1|UniProtKB=W5N3G9 W5N3G9 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000005707.1|UniProtKB=W5MET3 W5MET3 PTHR46396:SF1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003205.1|UniProtKB=W5M5Y3 W5M5Y3 PTHR46906:SF1 HEAT SHOCK PROTEIN BETA-8 HEAT SHOCK PROTEIN BETA-8 response to organic substance#GO:0010033;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to organic substance#GO:0071310;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014852.1|UniProtKB=W5NCC8 W5NCC8 PTHR24241:SF69 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE II RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000018131.1|UniProtKB=W5NNM3 W5NNM3 PTHR10489:SF922 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR FAMILY-LIKE-RELATED signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008484.1|UniProtKB=W5MPM7 W5MPM7 PTHR10644:SF2 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010970.1|UniProtKB=W5MYJ8 W5MYJ8 CTBP1 PTHR46029:SF2 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 LEPOC|Ensembl=ENSLOCG00000005051.1|UniProtKB=W5MCH1 W5MCH1 PTHR46768:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 2 TWO PORE CHANNEL PROTEIN 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;biological process involved in interaction with host#GO:0051701;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 ion channel#PC00133;transporter#PC00227 CCKR signaling map#P06959>TPC1/2#P07209 LEPOC|Ensembl=ENSLOCG00000004717.1|UniProtKB=W5MB90 W5MB90 ASTN2 PTHR16592:SF2 ASTROTACTIN-1-LIKE ASTROTACTIN-2 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;cell differentiation#GO:0030154;neuron migration#GO:0001764;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012383.1|UniProtKB=W5N3P0 W5N3P0 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 LEPOC|Ensembl=ENSLOCG00000012386.1|UniProtKB=W5N3Q0 W5N3Q0 PTHR12939:SF6 SARCOGLYCAN DELTA-SARCOGLYCAN blood circulation#GO:0008015;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;developmental process#GO:0032502;circulatory system process#GO:0003013;tissue development#GO:0009888;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000005655.1|UniProtKB=W5MEM5 W5MEM5 PTHR23068:SF53 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5-)-METHYLTRANSFERASE nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;DNA methylation#GO:0006306;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;DNA modification#GO:0006304;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;DNA alkylation#GO:0006305;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000004562.1|UniProtKB=W5MAQ3 W5MAQ3 PTHR10827:SF17 RETICULOCALBIN RETICULOCALBIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009031.1|UniProtKB=W5MRJ5 W5MRJ5 PTHR24340:SF34 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013644.1|UniProtKB=W5N862 W5N862 PTHR46946:SF1 NEURITE EXTENSION AND MIGRATION FACTOR NEURITE EXTENSION AND MIGRATION FACTOR regulation of cell-matrix adhesion#GO:0001952;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion mediated by integrin#GO:0033628 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006278.1|UniProtKB=W5MGT4 W5MGT4 PTHR10627:SF34 SCP160 VIGILIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002565.1|UniProtKB=W5M3R7 W5M3R7 PTHR11824:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;neuromuscular junction development#GO:0007528;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 LEPOC|Ensembl=ENSLOCG00000009833.1|UniProtKB=W5MUH6 W5MUH6 PTHR24418:SF61 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ITK_TSK protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;T cell differentiation#GO:0030217;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;response to stimulus#GO:0050896;immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000016104.1|UniProtKB=W5NGT2 W5NGT2 PTHR15186:SF3 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3-LIKE response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;apoptotic process#GO:0006915;cell death#GO:0008219;mitochondrion organization#GO:0007005;defense response to virus#GO:0051607;defense response#GO:0006952;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000010609.1|UniProtKB=W5MX92 W5MX92 PTHR15454:SF35 NISCHARIN RELATED NISCHARIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003253.1|UniProtKB=W5M632 W5M632 PTHR19441:SF95 WHEY ACDIC PROTEIN WAP PERLWAPIN ISOFORM X1 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000004551.1|UniProtKB=W5MAN4 W5MAN4 PTHR45682:SF6 AGAP008228-PA DUAL SPECIFICITY PHOSPHATASE 29 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000016691.1|UniProtKB=W5NJ17 W5NJ17 PTHR15508:SF2 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE DELTA-1 cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000002378.1|UniProtKB=W5M344 W5M344 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005978.1|UniProtKB=W5MFR7 W5MFR7 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005916.1|UniProtKB=W5MFL1 W5MFL1 PTHR10918:SF3 HOMER HOMER PROTEIN HOMOLOG 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of metal ion transport#GO:0010959;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of monoatomic ion transport#GO:0043269;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 Metabotropic glutamate receptor group I pathway#P00041>Homer#P01058 LEPOC|Ensembl=ENSLOCG00000014283.1|UniProtKB=W5NAC5 W5NAC5 PTHR46114:SF2 APPLE DOMAIN-CONTAINING PROTEIN CULLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003133.1|UniProtKB=W5M5N7 W5M5N7 PTHR24300:SF48 CYTOCHROME P450 508A4-RELATED VITAMIN D 25-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010629.1|UniProtKB=W5MXA9 W5MXA9 PTHR14134:SF2 E3 UBIQUITIN-PROTEIN LIGASE RAD18 E3 UBIQUITIN-PROTEIN LIGASE RAD18 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004860.1|UniProtKB=W5MBV0 W5MBV0 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007485.1|UniProtKB=W5ML28 W5ML28 PTHR11471:SF27 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>TRAIL#P00263 LEPOC|Ensembl=ENSLOCG00000010448.1|UniProtKB=W5MWP7 W5MWP7 PTHR14239:SF6 DUDULIN-RELATED METALLOREDUCTASE STEAP2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017983.1|UniProtKB=W5NN75 W5NN75 PTHR24248:SF177 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR D7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic cyclic compound#GO:0014070;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;dopamine receptor signaling pathway#GO:0007212;regulation of signal transduction#GO:0009966;cellular response to organic cyclic compound#GO:0071407;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008571.1|UniProtKB=W5MPW7 W5MPW7 PTHR15040:SF2 DERMATOPONTIN-RELATED DERMATOPONTIN cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;collagen fibril organization#GO:0030199;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005286.1|UniProtKB=W5MDB1 W5MDB1 PCDH8 PTHR24028:SF46 CADHERIN-87A PROTOCADHERIN-8 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000005918.1|UniProtKB=W5MFK6 W5MFK6 PTHR10336:SF6 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE EPSILON-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;small GTPase-mediated signal transduction#GO:0007264;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;Ras protein signal transduction#GO:0007265;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000013883.1|UniProtKB=W5N909 W5N909 PTHR12484:SF4 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A LEPOC|Ensembl=ENSLOCG00000003823.1|UniProtKB=W5M868 W5M868 PTHR24351:SF48 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CCKR signaling map#P06959>p70S6K1#P07031;p53 pathway by glucose deprivation#P04397>S6K#P04636;PI3 kinase pathway#P00048>S6K#P01194;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000015603.1|UniProtKB=W5NEZ8 W5NEZ8 PTHR24211:SF1 LIM DOMAIN-CONTAINING PROTEIN TESTIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008900.1|UniProtKB=W5MR37 W5MR37 PTHR11733:SF195 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME-LIKE 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 LEPOC|Ensembl=ENSLOCG00000012963.1|UniProtKB=W5N5Q7 W5N5Q7 PTHR21580:SF60 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT-CONTAINING PROTEIN 2 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016782.1|UniProtKB=W5NJD6 W5NJD6 PTHR12400:SF26 INOSITOL POLYPHOSPHATE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000010705.1|UniProtKB=W5MXK2 W5MXK2 PTHR15949:SF3 TESTIS-EXPRESSED PROTEIN 264 TESTIS-EXPRESSED PROTEIN 264 LEPOC|Ensembl=ENSLOCG00000006045.1|UniProtKB=W5MFZ7 W5MFZ7 PTHR11699:SF228 ALDEHYDE DEHYDROGENASE-RELATED 4-TRIMETHYLAMINOBUTYRALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000013672.1|UniProtKB=W5N894 W5N894 PTHR10807:SF39 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 10 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013828.1|UniProtKB=W5N8U0 W5N8U0 PTHR24056:SF164 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 21 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005841.1|UniProtKB=W5MF94 W5MF94 PTHR46838:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of lymphocyte migration#GO:2000401;positive regulation of protein modification process#GO:0031401;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;positive regulation of cytokine production#GO:0001819;defense response#GO:0006952;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;defense response to Gram-positive bacterium#GO:0050830;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;defense response to Gram-negative bacterium#GO:0050829;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of leukocyte migration#GO:0002687;negative regulation of multicellular organismal process#GO:0051241;positive regulation of biosynthetic process#GO:0009891;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of leukocyte activation#GO:0002694;regulation of cellular biosynthetic process#GO:0031326;positive regulation of cell migration#GO:0030335;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009082.1|UniProtKB=W5MRR2 W5MRR2 PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006634.1|UniProtKB=W5MI05 W5MI05 PTHR42908:SF28 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2 GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;ribosome binding#GO:0043022;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000014931.1|UniProtKB=W5NCN1 W5NCN1 PTHR22951:SF11 CLATHRIN ASSEMBLY PROTEIN ENTH DOMAIN-CONTAINING PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;establishment of organelle localization#GO:0051656;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000007915.1|UniProtKB=W5MMK7 W5MMK7 PTHR14057:SF44 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006313.1|UniProtKB=W5MGY7 W5MGY7 PTHR10980:SF8 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002970.1|UniProtKB=W5M539 W5M539 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008037.1|UniProtKB=W5MN14 W5MN14 PTHR31859:SF7 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39A LEPOC|Ensembl=ENSLOCG00000012664.1|UniProtKB=W5N4M3 W5N4M3 PTHR44427:SF5 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011468.1|UniProtKB=W5N0D3 W5N0D3 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 LEPOC|Ensembl=ENSLOCG00000015437.1|UniProtKB=W5NEE3 W5NEE3 PTHR11309:SF87 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>sFRP#P01434 LEPOC|Ensembl=ENSLOCG00000008587.1|UniProtKB=W5MPY2 W5MPY2 PTHR14154:SF2 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 LEPOC|Ensembl=ENSLOCG00000002968.1|UniProtKB=W5M534 W5M534 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000003120.1|UniProtKB=W5M5M1 W5M5M1 PTHR10505:SF16 CALCITONIN-RELATED CALCITONIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 CCKR signaling map#P06959>CALCA#G07282;CCKR signaling map#P06959>CALCA#G06988 LEPOC|Ensembl=ENSLOCG00000005681.1|UniProtKB=W5MEP9 W5MEP9 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of apoptotic process#GO:0042981;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein modification process#GO:0031401;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CCKR signaling map#P06959>BIRC2#G07278;Apoptosis signaling pathway#P00006>c-IAP1,2#P00264 LEPOC|Ensembl=ENSLOCG00000005522.1|UniProtKB=W5ME57 W5ME57 PTHR24153:SF0 ESPIN ESPIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament bundle organization#GO:0061572 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000000729.1|UniProtKB=W5LXF1 W5LXF1 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000012668.1|UniProtKB=W5N4M9 W5N4M9 PTHR10177:SF363 CYCLINS G1_S-SPECIFIC CYCLIN-D3 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000012155.1|UniProtKB=W5N2T6 W5N2T6 MDFI PTHR15304:SF1 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR LEPOC|Ensembl=ENSLOCG00000005757.1|UniProtKB=W5MEZ6 W5MEZ6 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010129.1|UniProtKB=W5MVI6 W5MVI6 PTHR15426:SF6 PROTEIN DEPP1 PROTEIN DEPP1 regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;regulation of cellular catabolic process#GO:0031329;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012921.1|UniProtKB=W5N5K4 W5N5K4 PTHR24240:SF22 OPSIN PHOTOPIGMENT MELANOPSIN-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000508.1|UniProtKB=W5LWQ5 W5LWQ5 PTHR12483:SF22 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS HIGH AFFINITY COPPER UPTAKE PROTEIN 1 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015809.1|UniProtKB=W5NFQ1 W5NFQ1 PTHR24240:SF167 OPSIN NOVOPSIN-7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008027.1|UniProtKB=W5MN05 W5MN05 EEF1AKMT2 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007400.1|UniProtKB=W5MKT7 W5MKT7 PTHR18896:SF57 PHOSPHOLIPASE D PHOSPHOLIPASE D1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;lipid catabolic process#GO:0016042;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate catabolic process#GO:0046434;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;phospholipid catabolic process#GO:0009395;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular membrane-bounded organelle#GO:0043231;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 phospholipase#PC00186 Ras Pathway#P04393>PLD#P04574;Angiogenesis#P00005>PLD#P00204 LEPOC|Ensembl=ENSLOCG00000000898.1|UniProtKB=W5LXZ2 W5LXZ2 PTHR10924:SF2 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED HEME TRANSPORTER FLVCR1 tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;metal ion transport#GO:0030001;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;cellular process#GO:0009987;erythrocyte differentiation#GO:0030218;localization#GO:0051179;mitochondrial transport#GO:0006839;cell development#GO:0048468;cell differentiation#GO:0030154;organic substance transport#GO:0071702;immune system process#GO:0002376;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;hemopoiesis#GO:0030097;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002027.1|UniProtKB=W5M1U5 W5M1U5 PTHR23085:SF26 GH28348P JUNCTOPHILIN-2 sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015620.1|UniProtKB=W5NF22 W5NF22 PTHR11276:SF42 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000005131.1|UniProtKB=W5MCT8 W5MCT8 HAGHL PTHR11935:SF77 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 LEPOC|Ensembl=ENSLOCG00000008551.1|UniProtKB=W5MPU2 W5MPU2 PTHR19849:SF1 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN F-BOX_WD REPEAT-CONTAINING PROTEIN 7 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Sel 10#P01102;Parkinson disease#P00049>hSel10#P01240 LEPOC|Ensembl=ENSLOCG00000004725.1|UniProtKB=W5MBA2 W5MBA2 PTHR16134:SF19 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH REPEAT PROTEIN 18 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004334.1|UniProtKB=W5M9X8 W5M9X8 PTHR12174:SF39 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2B hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;Golgi-associated vesicle membrane#GO:0030660;endoplasmic reticulum subcompartment#GO:0098827;lysosome#GO:0005764;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013571.1|UniProtKB=W5N7X9 W5N7X9 PTHR11036:SF78 SEMAPHORIN SEMAPHORIN-5A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;axon guidance#GO:0007411;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell communication#GO:0007154;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003307.1|UniProtKB=W5M691 W5M691 LEKR1 PTHR34251:SF1 LEUCINE-, GLUTAMATE- AND LYSINE-RICH PROTEIN 1 LEUCINE, GLUTAMATE AND LYSINE RICH 1 LEPOC|Ensembl=ENSLOCG00000005868.1|UniProtKB=W5MFC8 W5MFC8 SNIP1 PTHR23308:SF36 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 SMAD NUCLEAR-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000012462.1|UniProtKB=W5N3Y3 W5N3Y3 PTHR46216:SF4 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER G-PROTEIN COUPLED RECEPTOR 37-LIKE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 LEPOC|Ensembl=ENSLOCG00000018297.1|UniProtKB=W5NP39 W5NP39 PTHR11462:SF37 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUNB cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 LEPOC|Ensembl=ENSLOCG00000004221.1|UniProtKB=W5M9J4 W5M9J4 PTHR31183:SF2 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;keratin filament#GO:0045095;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015726.1|UniProtKB=W5NFF6 W5NFF6 PTHR24131:SF8 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017897.1|UniProtKB=W5NMZ1 W5NMZ1 PTHR15437:SF1 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 2, MITOCHONDRIAL nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 LEPOC|Ensembl=ENSLOCG00000016571.1|UniProtKB=W5NIL4 W5NIL4 PTHR11785:SF246 AMINO ACID TRANSPORTER CYSTINE_GLUTAMATE TRANSPORTER L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011028.1|UniProtKB=W5MYS6 W5MYS6 PTHR11213:SF1 GLUCAGON-FAMILY NEUROPEPTIDE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;regulation of signal transduction#GO:0009966;neuropeptide signaling pathway#GO:0007218;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of protein localization#GO:0032880;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;positive regulation of ERK1 and ERK2 cascade#GO:0070374 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;perikaryon#GO:0043204;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 neuropeptide#PC00162;intercellular signal molecule#PC00207;peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#P06800;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06879;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06667 LEPOC|Ensembl=ENSLOCG00000015728.1|UniProtKB=W5NFF1 W5NFF1 PTHR24064:SF461 SOLUTE CARRIER FAMILY 22 MEMBER ORGANIC CATION TRANSPORTER 2 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic cation transport#GO:0015695;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000440.1|UniProtKB=W5LWH3 W5LWH3 PTHR10129:SF9 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAF sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000000466.1|UniProtKB=W5LWK8 W5LWK8 PTHR45632:SF6 LD33804P KELCH-LIKE PROTEIN 14 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005467.1|UniProtKB=W5MDY4 W5MDY4 PTHR10671:SF25 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS INTRINSIC MEMBRANE PROTEIN 2.1-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008123.1|UniProtKB=W5MNA9 W5MNA9 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U4#P01476 LEPOC|Ensembl=ENSLOCG00000017849.1|UniProtKB=W5NMU3 W5NMU3 KCNJ4 PTHR11767:SF53 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011903.1|UniProtKB=W5N1X8 W5N1X8 PTHR22761:SF77 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4C endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013774.1|UniProtKB=W5N8M6 W5N8M6 PTHR14186:SF20 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED CYSTEINE-RICH MOTOR NEURON 1 PROTEIN-LIKE regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000003614.1|UniProtKB=W5M7C8 W5M7C8 PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 LEPOC|Ensembl=ENSLOCG00000006769.1|UniProtKB=W5MII6 W5MII6 PTHR10037:SF23 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 8 SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007622.1|UniProtKB=W5MLI8 W5MLI8 PTHR24020:SF77 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 1 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000002519.1|UniProtKB=W5M3J9 W5M3J9 PTHR11559:SF416 CARBOXYLESTERASE COCAINE ESTERASE esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009094.1|UniProtKB=W5MRS8 W5MRS8 PTHR23349:SF97 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000000455.1|UniProtKB=W5LWJ1 W5LWJ1 PTHR11224:SF39 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002170.1|UniProtKB=W5M2B9 W5M2B9 PTHR43313:SF3 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 LEPOC|Ensembl=ENSLOCG00000008620.1|UniProtKB=W5MQ22 W5MQ22 PTHR24417:SF8 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010120.1|UniProtKB=W5MVH6 W5MVH6 TRMT5 PTHR23245:SF36 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000000646.1|UniProtKB=W5LX58 W5LX58 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000016519.1|UniProtKB=W5NIE5 W5NIE5 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000002243.1|UniProtKB=W5M2N6 W5M2N6 PTHR48027:SF23 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED DAZ ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;male gamete generation#GO:0048232;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;spermatogenesis#GO:0007283;reproductive process#GO:0022414;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;multicellular organismal reproductive process#GO:0048609;positive regulation of mRNA metabolic process#GO:1903313;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010512.1|UniProtKB=W5MWX2 W5MWX2 PTHR14239:SF5 DUDULIN-RELATED METALLOREDUCTASE STEAP4 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017945.1|UniProtKB=W5NN39 W5NN39 PTHR20899:SF4 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 2 PROTEIN LEPOC|Ensembl=ENSLOCG00000009668.1|UniProtKB=W5MTW1 W5MTW1 PTHR13285:SF19 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT-LIKE PROTEIN palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;protein palmitoylation#GO:0018345;protein lipidation#GO:0006497;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;lipoprotein metabolic process#GO:0042157;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000008745.1|UniProtKB=W5MQI7 W5MQI7 PTHR10556:SF57 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009330.1|UniProtKB=W5MSM5 W5MSM5 PTHR11153:SF17 SIDEROFLEXIN SIDEROFLEXIN-5 citrate transmembrane transporter activity#GO:0015137;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012807.1|UniProtKB=W5N560 W5N560 PTHR18952:SF120 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 2 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000004281.1|UniProtKB=W5M9R0 W5M9R0 PTHR12411:SF57 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L2 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016817.1|UniProtKB=W5NJH6 W5NJH6 PTHR12081:SF19 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003437.1|UniProtKB=W5M6R5 W5M6R5 PTHR23245:SF31 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510;glycosyl compound metabolic process#GO:1901657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000010295.1|UniProtKB=W5MW55 W5MW55 PTHR10730:SF8 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013908.1|UniProtKB=W5N936 W5N936 PTHR24028:SF254 CADHERIN-87A PROTOCADHERIN-11 X-LINKED-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000002042.1|UniProtKB=W5M1W1 W5M1W1 PTHR23402:SF1 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE I cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001688.1|UniProtKB=W5M0N3 W5M0N3 TNFRSF6B PTHR23097:SF116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003520.1|UniProtKB=W5M732 W5M732 PTHR45858:SF2 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 LEPOC|Ensembl=ENSLOCG00000001329.1|UniProtKB=W5LZF5 W5LZF5 PTHR15751:SF11 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;binding#GO:0005488;GABA receptor binding#GO:0050811 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;endosome to lysosome transport#GO:0008333;nervous system development#GO:0007399;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;mitochondrion organization#GO:0007005;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;vacuolar transport#GO:0007034;multicellular organism development#GO:0007275;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;mitochondrion#GO:0005739;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001714.1|UniProtKB=W5M0S4 W5M0S4 PTHR11785:SF354 AMINO ACID TRANSPORTER B(0,+)-TYPE AMINO ACID TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010985.1|UniProtKB=W5MYL6 W5MYL6 PTHR10970:SF2 CLUSTERIN CLUSTERIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008197.1|UniProtKB=W5MNJ3 W5MNJ3 PTHR13678:SF12 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37D cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011973.1|UniProtKB=W5N266 W5N266 TXK PTHR24418:SF219 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TEC protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;adaptive immune response#GO:0002250;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000012737.1|UniProtKB=W5N4W2 W5N4W2 PTHR34340:SF1 MELANOREGULIN MELANOREGULIN LEPOC|Ensembl=ENSLOCG00000014567.1|UniProtKB=W5NBC8 W5NBC8 PTHR24023:SF1071 COLLAGEN ALPHA COLLAGEN ALPHA-1(VII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000008015.1|UniProtKB=W5MMX5 W5MMX5 PTHR23192:SF36 OLFACTOMEDIN-RELATED NOELIN-3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006234.1|UniProtKB=W5MGL7 W5MGL7 KY PTHR46333:SF3 CYTOKINESIS PROTEIN 3 KYPHOSCOLIOSIS PEPTIDASE muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;muscle organ development#GO:0007517;anatomical structure development#GO:0048856;animal organ development#GO:0048513;cell junction organization#GO:0034330;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;neuromuscular junction development#GO:0007528 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008170.1|UniProtKB=W5MNF9 W5MNF9 PTHR47385:SF12 CALPONIN CALPONIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017335.1|UniProtKB=W5NLD1 W5NLD1 PTHR21461:SF45 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014995.1|UniProtKB=W5NCV6 W5NCV6 PTHR10732:SF0 40S RIBOSOMAL PROTEIN S17 40S RIBOSOMAL PROTEIN S17 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006720.1|UniProtKB=W5MIA8 W5MIA8 PTHR14309:SF8 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 2 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008361.1|UniProtKB=W5MP44 W5MP44 PTHR31635:SF196 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000015544.1|UniProtKB=W5NES6 W5NES6 IMPDH PTHR11911:SF74 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 LEPOC|Ensembl=ENSLOCG00000009328.1|UniProtKB=W5MSL8 W5MSL8 EFCAB9 PTHR47065:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002225.1|UniProtKB=W5M2I3 W5M2I3 KIF27 PTHR24115:SF889 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF27 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014154.1|UniProtKB=W5N9Y0 W5N9Y0 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000007997.1|UniProtKB=W5MMV5 W5MMV5 PTHR11492:SF3 NUCLEAR FACTOR I NUCLEAR FACTOR 1 X-TYPE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001864.1|UniProtKB=W5M1A0 W5M1A0 PTHR46149:SF5 MIP08469P DEXAMETHASONE-INDUCED RAS-RELATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000008612.1|UniProtKB=W5MQ08 W5MQ08 PTHR15249:SF0 TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR Toll receptor signaling pathway#P00054>TANK#P01353 LEPOC|Ensembl=ENSLOCG00000011324.1|UniProtKB=W5MZV7 W5MZV7 PTHR19143:SF433 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;complement activation#GO:0006956 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002540.1|UniProtKB=W5M3P6 W5M3P6 PTHR23138:SF94 RAN BINDING PROTEIN RAN BINDING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017332.1|UniProtKB=W5NLC8 W5NLC8 RNF208 PTHR22791:SF3 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 208 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017449.1|UniProtKB=W5NLP5 W5NLP5 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008318.1|UniProtKB=W5MNZ7 W5MNZ7 PTHR46678:SF2 LECITHIN RETINOL ACYLTRANSFERASE LECITHIN RETINOL ACYLTRANSFERASE-LIKE-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 retinoid metabolic process#GO:0001523;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;retinol metabolic process#GO:0042572;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;diterpenoid metabolic process#GO:0016101;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;terpenoid metabolic process#GO:0006721;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000017055.1|UniProtKB=W5NKC4 W5NKC4 PTHR16130:SF2 LYSOSOMAL COBALAMIN TRANSPORTER-RELATED LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to vacuole#GO:0072665;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014707.1|UniProtKB=W5NBU8 W5NBU8 PTHR24204:SF2 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;cell projection morphogenesis#GO:0048858;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000066.1|UniProtKB=W5LVC0 W5LVC0 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010715.1|UniProtKB=W5MXM0 W5MXM0 PTHR42899:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 LEPOC|Ensembl=ENSLOCG00000012176.1|UniProtKB=W5N2W5 W5N2W5 PTHR24248:SF169 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008100.1|UniProtKB=W5MN80 W5MN80 PTHR13793:SF27 PHD FINGER PROTEINS PROTEIN JADE-3 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012824.1|UniProtKB=W5N572 W5N572 PTHR17600:SF2 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD LEPOC|Ensembl=ENSLOCG00000003995.1|UniProtKB=W5M8R1 W5M8R1 PTHR11010:SF117 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED SERINE PROTEASE 16 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015967.1|UniProtKB=W5NGA3 W5NGA3 PTHR11438:SF2 PROENKEPHALIN PREPRONOCICEPTIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;cell body#GO:0044297;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 neuropeptide#PC00162;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000008366.1|UniProtKB=W5MP51 W5MP51 PTHR33198:SF20 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017494.1|UniProtKB=W5NLU0 W5NLU0 P2RY4 PTHR24231:SF21 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010878.1|UniProtKB=W5MY71 W5MY71 PTHR24359:SF19 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011469.1|UniProtKB=W5N0D4 W5N0D4 PTHR24139:SF34 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 85_88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738 LEPOC|Ensembl=ENSLOCG00000009951.1|UniProtKB=W5MUW0 W5MUW0 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007620.1|UniProtKB=W5MLI6 W5MLI6 PTHR23255:SF66 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II SERINE_THREONINE-PROTEIN KINASE RECEPTOR R3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;system development#GO:0048731;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;tube development#GO:0035295;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000012955.1|UniProtKB=W5N5R0 W5N5R0 PTHR31540:SF1 CENTROSOMAL PROTEIN OF 131 KDA CENTROSOMAL PROTEIN OF 131 KDA LEPOC|Ensembl=ENSLOCG00000001991.1|UniProtKB=W5M1P9 W5M1P9 PTHR24240:SF152 OPSIN OPSIN, PINEAL-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006684.1|UniProtKB=W5MI62 W5MI62 PTHR43716:SF1 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009346.1|UniProtKB=W5MSP3 W5MSP3 PTHR11890:SF22 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;negative regulation of transport#GO:0051051;negative regulation of cellular process#GO:0048523;regulation of vesicle-mediated transport#GO:0060627;regulation of exocytosis#GO:0017157 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005169.1|UniProtKB=W5MCW4 W5MCW4 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008678.1|UniProtKB=W5MQ94 W5MQ94 PTHR42753:SF10 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004029.1|UniProtKB=W5M8V7 W5M8V7 PTHR11715:SF3 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED macromolecule modification#GO:0043412;protein modification process#GO:0036211;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;protein metabolic process#GO:0019538;L-amino acid metabolic process#GO:0170033;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008715.1|UniProtKB=W5MQF0 W5MQF0 PTHR12929:SF6 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3-B transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014013.1|UniProtKB=W5N9G3 W5N9G3 PTHR12149:SF8 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN PROTEIN-RIBULOSAMINE 3-KINASE transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005289.1|UniProtKB=W5MDB4 W5MDB4 PTHR24304:SF1 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7A1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002176.1|UniProtKB=W5M2C6 W5M2C6 PTHR34828:SF1 TESTIS-EXPRESSED PROTEIN 45 TESTIS-EXPRESSED PROTEIN 45 LEPOC|Ensembl=ENSLOCG00000002499.1|UniProtKB=W5M3H5 W5M3H5 PTHR15016:SF6 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 LEPOC|Ensembl=ENSLOCG00000014643.1|UniProtKB=W5NBL8 W5NBL8 PTHR23280:SF5 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 5 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003256.1|UniProtKB=W5M638 W5M638 CYB5RL PTHR19370:SF184 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE-LIKE reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015056.1|UniProtKB=W5ND23 W5ND23 PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008516.1|UniProtKB=W5MPQ2 W5MPQ2 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012300.1|UniProtKB=W5N3D3 W5N3D3 PTHR24129:SF0 ANKYCORBIN ANKYCORBIN LEPOC|Ensembl=ENSLOCG00000015877.1|UniProtKB=W5NFZ3 W5NFZ3 PTHR45783:SF6 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 4 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000003814.1|UniProtKB=W5M846 W5M846 PTHR23503:SF1 SOLUTE CARRIER FAMILY 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004110.1|UniProtKB=W5M954 W5M954 PTHR43134:SF7 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA CELL DIVISION PROTEIN FTSY HOMOLOG, CHLOROPLASTIC GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015099.1|UniProtKB=W5ND74 W5ND74 PTHR22922:SF5 GPI-ANCHORED PROTEIN P137 CAPRIN-2 nucleic acid binding#GO:0003676;protein binding#GO:0005515;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of Wnt signaling pathway#GO:0030177;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014507.1|UniProtKB=W5NB49 W5NB49 PTHR43851:SF4 FAMILY NOT NAMED ATYPICAL KINASE COQ8B, MITOCHONDRIAL cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 LEPOC|Ensembl=ENSLOCG00000013382.1|UniProtKB=W5N794 W5N794 GRM7 PTHR24060:SF98 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000016234.1|UniProtKB=W5NHA9 W5NHA9 LGR5 PTHR24372:SF71 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of adenylate cyclase activity#GO:0045762;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of Wnt signaling pathway#GO:0030177;regulation of catalytic activity#GO:0050790;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;positive regulation of catalytic activity#GO:0043085;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016217.1|UniProtKB=W5NH87 W5NH87 KCNMB4 PTHR10258:SF3 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ligand-gated monoatomic cation channel activity#GO:0099094;channel regulator activity#GO:0016247;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000003564.1|UniProtKB=W5M762 W5M762 PTHR23167:SF3 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-B scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014425.1|UniProtKB=W5NAU5 W5NAU5 PTHR12307:SF40 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3F phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000011720.1|UniProtKB=W5N1A1 W5N1A1 SHC3 PTHR10337:SF4 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 3 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Shc#P00554;PDGF signaling pathway#P00047>Shc#P01175;FGF signaling pathway#P00021>Shc#P00639 LEPOC|Ensembl=ENSLOCG00000006754.1|UniProtKB=W5MIE9 W5MIE9 PTHR12812:SF1 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003793.1|UniProtKB=W5M820 W5M820 AK1 PTHR23359:SF59 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000010786.1|UniProtKB=W5MXW2 W5MXW2 PTHR22950:SF22 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 3 aromatic amino acid transmembrane transporter activity#GO:0015173;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;amide transmembrane transporter activity#GO:0042887;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;basic amino acid transport#GO:0015802;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015366.1|UniProtKB=W5NE66 W5NE66 PTHR24223:SF355 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017048.1|UniProtKB=W5NKA8 W5NKA8 PTHR10634:SF67 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000005302.1|UniProtKB=W5MDD4 W5MDD4 PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012801.1|UniProtKB=W5N542 W5N542 PTHR12277:SF55 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17C hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;regulation of synapse structure or activity#GO:0050803;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of postsynapse organization#GO:0099175;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005436.1|UniProtKB=W5MDU1 W5MDU1 PTHR21642:SF2 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN-LIKE heart morphogenesis#GO:0003007;system development#GO:0048731;heart development#GO:0007507;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501 LEPOC|Ensembl=ENSLOCG00000001261.1|UniProtKB=W5LZ67 W5LZ67 PTHR11850:SF68 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF2 DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004312.1|UniProtKB=W5M9U2 W5M9U2 PTHR12002:SF192 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000015032.1|UniProtKB=W5ND05 W5ND05 PTHR24351:SF98 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;signal transduction by p53 class mediator#GO:0072331;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000011471.1|UniProtKB=W5N0D5 W5N0D5 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;snRNA processing#GO:0016180;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;exosome (RNase complex)#GO:0000178 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000003556.1|UniProtKB=W5M780 W5M780 PTHR10527:SF5 IMPORTIN BETA IMPORTIN 5 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009370.1|UniProtKB=W5MSS2 W5MSS2 PTHR11042:SF166 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of translational initiation#GO:0006446;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2AK3#P06813 LEPOC|Ensembl=ENSLOCG00000008572.1|UniProtKB=W5MPW5 W5MPW5 PTHR11054:SF0 6-PHOSPHOGLUCONOLACTONASE 6-PHOSPHOGLUCONOLACTONASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007182.1|UniProtKB=W5MJY4 W5MJY4 PTHR10082:SF36 INTEGRIN BETA SUBUNIT INTEGRIN BETA-7 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;response to stimulus#GO:0050896;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 LEPOC|Ensembl=ENSLOCG00000020997.1|UniProtKB=Q8HQM3 Q8HQM3 ND5 PTHR42829:SF2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008179.1|UniProtKB=W5MNI2 W5MNI2 PTHR43313:SF2 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012761.1|UniProtKB=W5N4Z6 W5N4Z6 PTHR42790:SF19 AMINOTRANSFERASE KYNURENINE_ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000013735.1|UniProtKB=W5N8I7 W5N8I7 PTHR43903:SF3 NEUROLIGIN NEUROLIGIN-2 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016565.1|UniProtKB=W5NIJ9 W5NIJ9 PTHR46470:SF3 N-ACYLNEURAMINATE-9-PHOSPHATASE N-ACYLNEURAMINATE-9-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014577.1|UniProtKB=W5NBD3 W5NBD3 PTHR22984:SF23 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013229.1|UniProtKB=W5N6N7 W5N6N7 PTHR22802:SF402 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER E membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005711.1|UniProtKB=W5MEV4 W5MEV4 TARBP2 PTHR46205:SF1 LOQUACIOUS, ISOFORM B RISC-LOADING COMPLEX SUBUNIT TARBP2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;endoribonuclease complex#GO:1902555;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007229.1|UniProtKB=W5MK41 W5MK41 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000017046.1|UniProtKB=W5NKA6 W5NKA6 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001428.1|UniProtKB=W5LZS0 W5LZS0 PTHR21258:SF46 DOCKING PROTEIN RELATED DOCKING PROTEIN 1 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 LEPOC|Ensembl=ENSLOCG00000005951.1|UniProtKB=W5MFM9 W5MFM9 PTHR31516:SF18 STABILIZER OF AXONEMAL MICROTUBULES 2 TRANSLATION INITIATION FACTOR IF-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000004885.1|UniProtKB=W5MBX1 W5MBX1 GPR180 PTHR23252:SF29 INTIMAL THICKNESS RECEPTOR-RELATED INTEGRAL MEMBRANE PROTEIN GPR180 LEPOC|Ensembl=ENSLOCG00000004525.1|UniProtKB=W5MAK4 W5MAK4 PTHR12161:SF5 IST1 FAMILY MEMBER IST1 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 LEPOC|Ensembl=ENSLOCG00000000148.1|UniProtKB=W5LVK7 W5LVK7 PTHR13585:SF19 CHASCON, ISOFORM D-RELATED ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000001436.1|UniProtKB=W5LZV5 W5LZV5 C1orf112 PTHR16071:SF2 CHROMOSOME 1 OPEN READING FRAME 112 FIGNL1-INTERACTING REGULATOR OF RECOMBINATION AND MITOSIS LEPOC|Ensembl=ENSLOCG00000010860.1|UniProtKB=W5MY50 W5MY50 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000008016.1|UniProtKB=W5MMX8 W5MMX8 PTHR31728:SF1 ABRAXAS FAMILY MEMBER BRISC COMPLEX SUBUNIT ABRAXAS 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;macromolecule modification#GO:0043412;nuclear division#GO:0000280;protein K63-linked deubiquitination#GO:0070536;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;establishment of organelle localization#GO:0051656;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017032.1|UniProtKB=W5NK90 W5NK90 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015427.1|UniProtKB=W5NEC9 W5NEC9 PLCZ1 PTHR10336:SF29 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ZETA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cell activation#GO:0001775;fertilization#GO:0009566;reproduction#GO:0000003;regulation of biological quality#GO:0065008;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;positive regulation of cytosolic calcium ion concentration#GO:0007204;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000002164.1|UniProtKB=W5M2B6 W5M2B6 PTHR11534:SF2 MYOGENIC FACTOR MYOBLAST DETERMINATION PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 muscle organ development#GO:0007517;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012573.1|UniProtKB=W5N4B8 W5N4B8 PTHR14485:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23-LIKE LEPOC|Ensembl=ENSLOCG00000000745.1|UniProtKB=W5LXH0 W5LXH0 PTHR11422:SF5 T-CELL SURFACE GLYCOPROTEIN CD4 DIVERSE IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1.1 ISOFORM X1-RELATED binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;MHC protein binding#GO:0042287;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;lymphocyte activation#GO:0046649;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016773.1|UniProtKB=W5NJC5 W5NJC5 PTHR13049:SF2 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 LEPOC|Ensembl=ENSLOCG00000007278.1|UniProtKB=W5MKA4 W5MKA4 PTHR11977:SF86 VILLIN SUPERVILLIN ISOFORM X1 cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011144.1|UniProtKB=W5MZ83 W5MZ83 PTHR23049:SF57 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005365.1|UniProtKB=W5MDL6 W5MDL6 PTHR14130:SF3 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 17 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of organelle organization#GO:0033043;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000014886.1|UniProtKB=W5NCH1 W5NCH1 PTHR10210:SF117 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE N-TERMINAL DOMAIN-CONTAINING PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000018175.1|UniProtKB=W5NNR7 W5NNR7 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003087.1|UniProtKB=W5M5H6 W5M5H6 PTHR19818:SF69 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017602.1|UniProtKB=W5NM48 W5NM48 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004411.1|UniProtKB=W5MA60 W5MA60 PTHR11969:SF99 MAX DIMERIZATION, MAD MAX-BINDING PROTEIN MNT sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000011446.1|UniProtKB=W5N0A8 W5N0A8 PTHR15706:SF20 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 4 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018358.1|UniProtKB=W5NPA0 W5NPA0 PTHR23334:SF21 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000005513.1|UniProtKB=W5ME47 W5ME47 PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83A-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000007473.1|UniProtKB=W5ML26 W5ML26 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004458.1|UniProtKB=W5MAD0 W5MAD0 PTHR12601:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle localization#GO:0051640;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006805.1|UniProtKB=W5MIN2 W5MIN2 PTHR23220:SF4 INTEGRIN ALPHA INTEGRIN ALPHA-V cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;cell adhesion mediated by integrin#GO:0033627;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;cell-matrix adhesion#GO:0007160;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 CCKR signaling map#P06959>ITGAV#P07133;CCKR signaling map#P06959>ITGAV#G07293;CCKR signaling map#P06959>ITGAV#G06999;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000003904.1|UniProtKB=W5M8F7 W5M8F7 PTHR13076:SF5 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1B LEPOC|Ensembl=ENSLOCG00000016232.1|UniProtKB=W5NHA4 W5NHA4 PTHR23349:SF67 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 21 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000007422.1|UniProtKB=W5MKV0 W5MKV0 PTHR12027:SF104 WNT RELATED PROTEIN WNT molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012061.1|UniProtKB=W5N2I0 W5N2I0 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016649.1|UniProtKB=W5NIW0 W5NIW0 PTHR18861:SF1 ELKS/RAB6-INTERACTING/CAST PROTEIN ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1 structural molecule activity#GO:0005198 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;neuromuscular synaptic transmission#GO:0007274;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011434.1|UniProtKB=W5N091 W5N091 PTHR12708:SF0 DNA POLYMERASE EPSILON SUBUNIT B DNA POLYMERASE EPSILON SUBUNIT 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000003625.1|UniProtKB=W5M7E2 W5M7E2 PTHR45944:SF5 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011076.1|UniProtKB=W5MYY8 W5MYY8 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018269.1|UniProtKB=W5NP11 W5NP11 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005152.1|UniProtKB=W5MCU6 W5MCU6 PTHR19307:SF13 TUMOR PROTEIN D52 TUMOR PROTEIN D54 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004891.1|UniProtKB=W5MBY2 W5MBY2 PTHR44598:SF2 JUNCTIONAL ADHESION MOLECULE C JUNCTIONAL ADHESION MOLECULE C cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004959.1|UniProtKB=W5MC74 W5MC74 ITGA7 PTHR23220:SF90 INTEGRIN ALPHA INTEGRIN ALPHA-7 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;response to stimulus#GO:0050896;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000009016.1|UniProtKB=W5MRI3 W5MRI3 PTHR24006:SF710 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 38 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016699.1|UniProtKB=W5NJ22 W5NJ22 PTHR31353:SF9 FAM98 PROTEIN FAM98A intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004320.1|UniProtKB=W5M9U9 W5M9U9 PTHR45879:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 p38 MAPK pathway#P05918>CREB#P06027;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Enkephalin release#P05913>CREB#P05971;Apoptosis signaling pathway#P00006>ATF#P00302;CCKR signaling map#P06959>CREB1#P07232;Gonadotropin-releasing hormone receptor pathway#P06664>CREB#P06749;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000013179.1|UniProtKB=W5N6H6 W5N6H6 PTHR31164:SF1 RAD52 MOTIF-CONTAINING PROTEIN 1 RAD52 MOTIF-CONTAINING PROTEIN 1 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003112.1|UniProtKB=W5M5L2 W5M5L2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007157.1|UniProtKB=W5MJV9 W5MJV9 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;enzyme regulator activity#GO:0030234 response to external biotic stimulus#GO:0043207;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;detection of stimulus#GO:0051606;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;negative regulation of nitrogen compound metabolic process#GO:0051172;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000010734.1|UniProtKB=W5MXQ1 W5MXQ1 AREL1 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of apoptotic process#GO:0043066;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008482.1|UniProtKB=W5MPL2 W5MPL2 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014951.1|UniProtKB=W5NCP8 W5NCP8 PTHR23235:SF82 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005602.1|UniProtKB=W5MEF4 W5MEF4 PTHR46745:SF1 TSC22 DOMAIN FAMILY PROTEIN 1 TSC22 DOMAIN FAMILY PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell population proliferation#GO:0008284;negative regulation of apoptotic process#GO:0043066;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004982.1|UniProtKB=W5MC85 W5MC85 PTHR24330:SF4 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 2 HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009923.1|UniProtKB=W5MUS8 W5MUS8 PTHR24355:SF11 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 LEPOC|Ensembl=ENSLOCG00000018169.1|UniProtKB=W5NNR1 W5NNR1 PTHR24225:SF68 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008592.1|UniProtKB=W5MPZ2 W5MPZ2 PTHR23031:SF6 RHOPHILIN RHOPHILIN-1 negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament bundle assembly#GO:0032231;negative regulation of cellular process#GO:0048523 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009535.1|UniProtKB=W5MTE5 W5MTE5 PTHR28604:SF2 FAMILY NOT NAMED RIKEN CDNA 2610028H24 GENE LEPOC|Ensembl=ENSLOCG00000016377.1|UniProtKB=W5NHW7 W5NHW7 PTHR10159:SF45 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of growth#GO:0040008;regulation of multicellular organismal development#GO:2000026;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000008479.1|UniProtKB=W5MPL7 W5MPL7 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004303.1|UniProtKB=W5M9T1 W5M9T1 PTHR14614:SF14 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21A cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001748.1|UniProtKB=W5M0X2 W5M0X2 PTHR45679:SF1 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ALPHA-1,2-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004353.1|UniProtKB=W5M9Z2 W5M9Z2 PTHR11955:SF59 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 2 fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000010205.1|UniProtKB=W5MVT2 W5MVT2 PTHR24366:SF51 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS MATRIX-REMODELING-ASSOCIATED PROTEIN 5 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007683.1|UniProtKB=W5MLR7 W5MLR7 PTHR46884:SF1 COLLECTRIN COLLECTRIN EGF receptor signaling pathway#P00018>Ras#P00552 LEPOC|Ensembl=ENSLOCG00000016560.1|UniProtKB=W5NIJ5 W5NIJ5 PTHR16317:SF1 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING KICSTOR COMPLEX PROTEIN ITFG2 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006 protein-containing complex#GO:0032991 cell adhesion molecule#PC00069;integrin#PC00126 LEPOC|Ensembl=ENSLOCG00000011694.1|UniProtKB=W5N170 W5N170 PTHR24025:SF16 DESMOGLEIN FAMILY MEMBER FAT ATYPICAL CADHERIN 2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000008552.1|UniProtKB=W5MPU0 W5MPU0 PTHR11653:SF4 PARVALBUMIN ALPHA ONCOMODULIN-2-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017826.1|UniProtKB=W5NMS0 W5NMS0 PTHR21824:SF4 TRANSMEMBRANE PROTEIN 177 TRANSMEMBRANE PROTEIN 177 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000250.1|UniProtKB=W5LVW6 W5LVW6 PTHR11599:SF53 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-8 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001389.1|UniProtKB=W5LZN6 W5LZN6 PHB2 PTHR23222:SF1 PROHIBITIN PROHIBITIN-2 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000849.1|UniProtKB=W5LXU5 W5LXU5 PTHR10751:SF32 GUANYLATE BINDING PROTEIN ATLASTIN-3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002500.1|UniProtKB=W5M3I2 W5M3I2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005259.1|UniProtKB=W5MD74 W5MD74 PTHR24304:SF3 CYTOCHROME P450 FAMILY 7 CHOLESTEROL 7-ALPHA-MONOOXYGENASE steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004136.1|UniProtKB=W5M995 W5M995 PTHR10947:SF0 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 PHENYLALANINE--TRNA LIGASE BETA SUBUNIT catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004647.1|UniProtKB=W5MB04 W5MB04 PTHR17384:SF7 P-SELECTIN GLYCOPROTEIN LIGAND-1 P-SELECTIN GLYCOPROTEIN LIGAND 1 immune system process#GO:0002376;leukocyte migration#GO:0050900;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002510.1|UniProtKB=W5M3I7 W5M3I7 PTHR14096:SF34 APOLIPOPROTEIN L APOLIPOPROTEIN L3-LIKE-RELATED lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000009970.1|UniProtKB=W5MUY3 W5MUY3 PTHR12967:SF0 PROTEIN SHQ1 HOMOLOG PROTEIN SHQ1 HOMOLOG protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009775.1|UniProtKB=W5MU81 W5MU81 PTHR10285:SF126 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000015551.1|UniProtKB=W5NET7 W5NET7 PTHR10666:SF458 UBIQUITIN POLYUBIQUITIN-C nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004830.1|UniProtKB=W5MBQ3 W5MBQ3 PTHR10822:SF31 GLYPICAN GLYPICAN-6 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;regulation of cellular localization#GO:0060341;regulation of protein localization#GO:0032880 cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017711.1|UniProtKB=W5NMF7 W5NMF7 PTHR15344:SF20 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 3-LIKE enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;small GTPase-mediated signal transduction#GO:0007264;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of anatomical structure size#GO:0090066;cellular response to stimulus#GO:0051716;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012174.1|UniProtKB=W5N2W1 W5N2W1 PTHR11984:SF32 CONNEXIN GAP JUNCTION DELTA-2 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000001181.1|UniProtKB=W5LYX5 W5LYX5 ABHD5 PTHR42886:SF34 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;phospholipid biosynthetic process#GO:0008654;regulation of catabolic process#GO:0009894;organophosphate biosynthetic process#GO:0090407;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of localization#GO:0032879;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of lipid catabolic process#GO:0050994;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;regulation of cellular catabolic process#GO:0031329;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;chemical homeostasis#GO:0048878;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;lipid homeostasis#GO:0055088;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002841.1|UniProtKB=W5M4M9 W5M4M9 PTHR10498:SF24 PARALEMMIN-RELATED A-KINASE ANCHOR PROTEIN 2 ISOFORM 3 (AKAP2) LEPOC|Ensembl=ENSLOCG00000017943.1|UniProtKB=W5NN37 W5NN37 PTHR22752:SF5 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 61 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;receptor complex#GO:0043235;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011376.1|UniProtKB=W5N021 W5N021 GRK5 PTHR24355:SF27 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 5 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK5#P05940;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 LEPOC|Ensembl=ENSLOCG00000009200.1|UniProtKB=W5MS69 W5MS69 PTHR45734:SF3 TENSIN TENSIN-1 ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000002887.1|UniProtKB=W5M4T7 W5M4T7 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002140.1|UniProtKB=W5M277 W5M277 PTHR10366:SF816 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000007354.1|UniProtKB=W5MKK1 W5MKK1 DTX3 PTHR12622:SF39 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015651.1|UniProtKB=W5NF56 W5NF56 PTHR11787:SF1 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010606.1|UniProtKB=W5MX83 W5MX83 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003486.1|UniProtKB=W5M6X2 W5M6X2 KCTD18 PTHR14499:SF4 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD18 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007316.1|UniProtKB=W5MKF1 W5MKF1 PTHR10845:SF34 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 1 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 LEPOC|Ensembl=ENSLOCG00000000910.1|UniProtKB=W5LY08 W5LY08 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001265.1|UniProtKB=W5LZ74 W5LZ74 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000010375.1|UniProtKB=W5MWG3 W5MWG3 P4HA2 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006969.1|UniProtKB=W5MJ73 W5MJ73 PTHR12652:SF7 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11B cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;peroxisome organization#GO:0007031 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008816.1|UniProtKB=W5MQS2 W5MQS2 PTHR43078:SF6 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 nucleotide binding#GO:0000166;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000013173.1|UniProtKB=W5N6G8 W5N6G8 PTHR12865:SF6 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;Golgi organization#GO:0007030;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;glycerolipid metabolic process#GO:0046486;organelle organization#GO:0006996;glycerophospholipid biosynthetic process#GO:0046474;vesicle organization#GO:0016050;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000015269.1|UniProtKB=W5NDS9 W5NDS9 PTHR10704:SF66 CARBOHYDRATE SULFOTRANSFERASE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011725.1|UniProtKB=W5N1A5 W5N1A5 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013939.1|UniProtKB=W5N975 W5N975 PTHR44305:SF2 SI:DKEY-192D15.2-RELATED SI:DKEY-192D15.2 LEPOC|Ensembl=ENSLOCG00000014741.1|UniProtKB=W5NBZ4 W5NBZ4 PTHR43884:SF12 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015378.1|UniProtKB=W5NE63 W5NE63 PTHR23318:SF18 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3B phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017703.1|UniProtKB=W5NME9 W5NME9 PTHR22889:SF0 WD REPEAT-CONTAINING PROTEIN 89 WD REPEAT-CONTAINING PROTEIN 89 LEPOC|Ensembl=ENSLOCG00000011050.1|UniProtKB=W5MYV4 W5MYV4 PTHR31878:SF1 CHEMOKINE-LIKE PROTEIN TAFA-5-RELATED PROTEIN FAM19A5 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000014956.1|UniProtKB=W5NCQ6 W5NCQ6 PTHR23235:SF46 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011053.1|UniProtKB=W5MYV9 W5MYV9 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015216.1|UniProtKB=W5NDL7 W5NDL7 PTHR13381:SF0 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000006884.1|UniProtKB=W5MIW8 W5MIW8 PTHR11339:SF384 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008007.1|UniProtKB=W5MMW6 W5MMW6 PTHR11831:SF5 30S 40S RIBOSOMAL PROTEIN 40S RIBOSOMAL PROTEIN S9 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000014906.1|UniProtKB=W5NCJ8 W5NCJ8 CXorf65 PTHR33887:SF4 PB1 DOMAIN-CONTAINING PROTEIN AB2-183 LEPOC|Ensembl=ENSLOCG00000014008.1|UniProtKB=W5N9H3 W5N9H3 PTHR10814:SF24 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 LEPOC|Ensembl=ENSLOCG00000007535.1|UniProtKB=W5ML87 W5ML87 YME1L1 PTHR23076:SF97 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002198.1|UniProtKB=W5M2F4 W5M2F4 PTHR24054:SF16 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 LEPOC|Ensembl=ENSLOCG00000010356.1|UniProtKB=W5MWE8 W5MWE8 PTHR10857:SF22 COPINE COPINE-3 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;phospholipid binding#GO:0005543;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000010702.1|UniProtKB=W5MXK0 W5MXK0 PTHR11890:SF3 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007873.1|UniProtKB=W5MMF0 W5MMF0 PTHR35257:SF1 TRANSMEMBRANE PROTEIN 82 TRANSMEMBRANE PROTEIN 82 LEPOC|Ensembl=ENSLOCG00000000356.1|UniProtKB=W5LW88 W5LW88 PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005634.1|UniProtKB=W5MEK2 W5MEK2 PITPNM2 PTHR10658:SF81 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PROTEIN RETINAL DEGENERATION B cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008682.1|UniProtKB=W5MQ98 W5MQ98 PTHR16134:SF119 F-BOX/TPR REPEAT PROTEIN POF3 AT02038P-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006473.1|UniProtKB=W5MHG1 W5MHG1 PTHR11941:SF45 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydratase#PC00120 LEPOC|Ensembl=ENSLOCG00000007234.1|UniProtKB=W5MK46 W5MK46 PTHR24393:SF151 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003766.1|UniProtKB=W5M805 W5M805 PTHR11359:SF2 AMP DEAMINASE AMP DEAMINASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 Purine metabolism#P02769>5'-AMP Deaminase#P03117 LEPOC|Ensembl=ENSLOCG00000003065.1|UniProtKB=W5M5G6 W5M5G6 SOX6 PTHR45789:SF1 FI18025P1 TRANSCRIPTION FACTOR SOX-6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013981.1|UniProtKB=W5N9C4 W5N9C4 PTHR10701:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009804.1|UniProtKB=W5MUC4 W5MUC4 PTHR23287:SF16 RUBY-EYE2-LIKE PROTEIN TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000062.1|UniProtKB=W5LVB5 W5LVB5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003595.1|UniProtKB=W5M7A0 W5M7A0 PTHR13857:SF42 MRNA EDITING ENZYME SINGLE-STRANDED DNA CYTOSINE DEAMINASE-LIKE nucleic acid binding#GO:0003676;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;DNA modification#GO:0006304;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA demethylation#GO:0080111;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009448.1|UniProtKB=W5MT37 W5MT37 BAZ1A PTHR46510:SF1 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;biological regulation#GO:0065007;regulation of chromatin organization#GO:1902275;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004919.1|UniProtKB=W5MC06 W5MC06 PTHR13455:SF3 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-ALPHA negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006928.1|UniProtKB=W5MJ21 W5MJ21 PTHR23302:SF42 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015334.1|UniProtKB=W5NE07 W5NE07 PTHR24070:SF388 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE KRAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;FGF signaling pathway#P00021>Ras#P00633;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Angiogenesis#P00005>Ras#P00238;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;Ras Pathway#P04393>Ras#P04547;PI3 kinase pathway#P00048>Ras#P01182;p53 pathway feedback loops 2#P04398>Ras#P04651;Integrin signalling pathway#P00034>Ras#P00916;VEGF signaling pathway#P00056>Ras#P01411 LEPOC|Ensembl=ENSLOCG00000002606.1|UniProtKB=W5M3V7 W5M3V7 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000003857.1|UniProtKB=W5M897 W5M897 PTHR11850:SF80 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX1 system development#GO:0048731;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501;anatomical structure formation involved in morphogenesis#GO:0048646 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>Prep1#P06829 LEPOC|Ensembl=ENSLOCG00000000067.1|UniProtKB=W5LVB9 W5LVB9 PTHR46780:SF21 PROTEIN EVA-1 ADHESION G PROTEIN-COUPLED RECEPTOR L3-RELATED LEPOC|Ensembl=ENSLOCG00000007352.1|UniProtKB=W5MKL0 W5MKL0 PTHR42735:SF1 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003444.1|UniProtKB=W5M6U2 W5M6U2 PTHR24072:SF311 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrion organization#GO:0007005;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004704.1|UniProtKB=W5MB77 W5MB77 PTHR24247:SF31 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2B signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;monoatomic cation transport#GO:0006812;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;transmembrane transport#GO:0055085;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;calcium ion transmembrane transport#GO:0070588;trans-synaptic signaling#GO:0099537;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000002666.1|UniProtKB=W5M424 W5M424 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011642.1|UniProtKB=W5N0Z3 W5N0Z3 PTHR45921:SF2 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005687.1|UniProtKB=W5MEQ8 W5MEQ8 C10orf53 PTHR28448:SF1 UPF0728 PROTEIN C10ORF53 UPF0728 PROTEIN C10ORF53 LEPOC|Ensembl=ENSLOCG00000016239.1|UniProtKB=W5NHB2 W5NHB2 PTHR12232:SF14 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3 ISOFORM 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018242.1|UniProtKB=W5NNY4 W5NNY4 PRLHR PTHR24235:SF11 NEUROPEPTIDE Y RECEPTOR PROLACTIN-RELEASING PEPTIDE RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002355.1|UniProtKB=W5M325 W5M325 PTHR46708:SF13 TENASCIN TENASCIN-R extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008395.1|UniProtKB=W5MP92 W5MP92 PTHR19143:SF332 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN BETA CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 platelet activation#GO:0030168;gene expression#GO:0010467;homotypic cell-cell adhesion#GO:0034109;wound healing#GO:0042060;biosynthetic process#GO:0009058;protein activation cascade#GO:0072376;platelet aggregation#GO:0070527;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;regulation of body fluid levels#GO:0050878;cell-cell adhesion#GO:0098609;protein maturation#GO:0051604;cell adhesion#GO:0007155;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;hemostasis#GO:0007599;coagulation#GO:0050817;primary metabolic process#GO:0044238;cell activation#GO:0001775;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;cell-matrix adhesion#GO:0007160;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Blood coagulation#P00011>Fibrinogen#P00406;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443 LEPOC|Ensembl=ENSLOCG00000007956.1|UniProtKB=W5MMQ3 W5MMQ3 PTHR24412:SF304 KELCH PROTEIN KELCH-LIKE PROTEIN 23 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005961.1|UniProtKB=W5MFN8 W5MFN8 PTHR46987:SF5 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-1 LEPOC|Ensembl=ENSLOCG00000004518.1|UniProtKB=W5MAJ6 W5MAJ6 PTHR24006:SF888 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004308.1|UniProtKB=W5M9U0 W5M9U0 PTHR14559:SF4 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005431.1|UniProtKB=W5MDU0 W5MDU0 PTHR22917:SF3 HEMOPEXIN DOMAIN-CONTAINING PROTEIN VITRONECTIN cell adhesion molecule binding#GO:0050839;extracellular matrix binding#GO:0050840;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell adhesion mediated by integrin#GO:0033627 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000017122.1|UniProtKB=W5NKK0 W5NKK0 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017928.1|UniProtKB=W5NN22 W5NN22 PTHR46077:SF1 E3 UBIQUITIN-PROTEIN LIGASE TOPORS TOP1 BINDING ARGININE_SERINE RICH PROTEIN, E3 UBIQUITIN LIGASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001526.1|UniProtKB=W5M037 W5M037 PTHR22997:SF6 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010453.1|UniProtKB=W5MWT7 W5MWT7 PTHR48051:SF38 FAMILY NOT NAMED LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010225.1|UniProtKB=W5MVW6 W5MVW6 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 small-subunit processome#GO:0032040;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008635.1|UniProtKB=W5MQ41 W5MQ41 PTHR21574:SF0 CENTROSOMAL PROTEIN OF 120 KDA CENTROSOMAL PROTEIN OF 120 KDA head development#GO:0060322;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;brain development#GO:0007420;cell population proliferation#GO:0008283;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;forebrain development#GO:0030900;system development#GO:0048731;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;central nervous system development#GO:0007417;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012375.1|UniProtKB=W5N3M9 W5N3M9 PTHR23170:SF3 NY-REN-58 ANTIGEN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45 LEPOC|Ensembl=ENSLOCG00000004727.1|UniProtKB=W5MBA9 W5MBA9 PTHR22804:SF24 AGGRECAN/VERSICAN PROTEOGLYCAN NEUROCAN CORE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000000480.1|UniProtKB=W5LWM0 W5LWM0 PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004998.1|UniProtKB=W5MCA7 W5MCA7 PTHR12190:SF1 A-KINASE ANCHOR PROTEIN AKAP 8 DBIRD COMPLEX SUBUNIT ZNF326 regulation of DNA-templated transcription elongation#GO:0032784;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011995.1|UniProtKB=W5N296 W5N296 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000010635.1|UniProtKB=W5MXB2 W5MXB2 PTHR11848:SF19 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 9 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000006227.1|UniProtKB=W5MGK8 W5MGK8 PTHR11592:SF5 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 7 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006863.1|UniProtKB=W5MIU6 W5MIU6 PTHR10201:SF30 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-9 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CCKR signaling map#P06959>MMP9#G07288;CCKR signaling map#P06959>MMP9#G06994;Plasminogen activating cascade#P00050>pro-MMP-9#P01259;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000010313.1|UniProtKB=W5MW84 W5MW84 PTHR11702:SF43 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009974.1|UniProtKB=W5MUY4 W5MUY4 PTHR24390:SF205 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN CONTAINING 49 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013782.1|UniProtKB=W5N8P2 W5N8P2 PTHR44170:SF20 PROTEIN SIDEKICK IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 3 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009939.1|UniProtKB=W5MUW3 W5MUW3 PTHR23255:SF70 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2B signaling receptor activity#GO:0038023;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780 LEPOC|Ensembl=ENSLOCG00000005183.1|UniProtKB=W5MCY2 W5MCY2 PTHR31108:SF6 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1 PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005405.1|UniProtKB=W5MDQ9 W5MDQ9 PTHR11849:SF307 ETS FEV TRANSCRIPTION FACTOR, ETS FAMILY MEMBER transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000006523.1|UniProtKB=W5MHL8 W5MHL8 PTHR11348:SF20 CONNECTIVE TISSUE GROWTH FACTOR-RELATED PROTEIN CYR61 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cell adhesion#GO:0007155;cell communication#GO:0007154;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;signaling#GO:0023052 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000008731.1|UniProtKB=W5MQI1 W5MQI1 PTHR16311:SF3 THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1 THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012979.1|UniProtKB=W5N5S7 W5N5S7 PTHR13767:SF2 TRNA-PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE TRUB1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008859.1|UniProtKB=W5MQW7 W5MQW7 PTHR21392:SF0 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 LEPOC|Ensembl=ENSLOCG00000008998.1|UniProtKB=W5MRG2 W5MRG2 LTN1 PTHR12389:SF0 ZINC FINGER PROTEIN 294 E3 UBIQUITIN-PROTEIN LIGASE LISTERIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 peptide metabolic process#GO:0006518;protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;translational elongation#GO:0006414 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004263.1|UniProtKB=W5M9N8 W5M9N8 PTHR45679:SF6 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005660.1|UniProtKB=W5MEM7 W5MEM7 PTHR17616:SF9 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER TRANSCRIPTIONAL COACTIVATOR YAP1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;hippo signaling#GO:0035329;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000002424.1|UniProtKB=W5M387 W5M387 PTHR19836:SF19 30S RIBOSOMAL PROTEIN S14 SMALL RIBOSOMAL SUBUNIT PROTEIN US14M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008666.1|UniProtKB=W5MQ86 W5MQ86 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000007420.1|UniProtKB=W5MKU8 W5MKU8 PTHR12121:SF35 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000004526.1|UniProtKB=W5MAL3 W5MAL3 PTHR43557:SF7 APOPTOSIS-INDUCING FACTOR 1 RIESKE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002105.1|UniProtKB=W5M232 W5M232 PTHR31609:SF1 YDJC DEACETYLASE FAMILY MEMBER CARBOHYDRATE DEACETYLASE hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000013002.1|UniProtKB=W5N5V6 W5N5V6 PTHR23343:SF31 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000002014.1|UniProtKB=W5M1S6 W5M1S6 PTHR10201:SF323 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000010485.1|UniProtKB=W5MWU2 W5MWU2 PRELID2 PTHR11158:SF20 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 2 phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001547.1|UniProtKB=W5M065 W5M065 SPEF1 PTHR12509:SF9 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLAR PROTEIN 1 ISOFORM X1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000010066.1|UniProtKB=W5MVA9 W5MVA9 PTHR18945:SF28 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;chloride transmembrane transporter activity#GO:0015108;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001907.1|UniProtKB=W5M1E9 W5M1E9 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014535.1|UniProtKB=W5NB82 W5NB82 PTHR43721:SF11 ELONGATION FACTOR TU-RELATED SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015308.1|UniProtKB=W5NDX8 W5NDX8 PTHR13803:SF29 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24C cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000012378.1|UniProtKB=W5N3N0 W5N3N0 PTHR15642:SF3 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017353.1|UniProtKB=W5NLE9 W5NLE9 C6orf120 PTHR31703:SF2 UPF0669 PROTEIN C6ORF120 UPF0669 PROTEIN C6ORF120 LEPOC|Ensembl=ENSLOCG00000009161.1|UniProtKB=W5MS14 W5MS14 PTHR15904:SF18 FAM13 PROTEIN FAM13A LEPOC|Ensembl=ENSLOCG00000008717.1|UniProtKB=W5MQF2 W5MQF2 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017569.1|UniProtKB=W5NM15 W5NM15 PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B LEPOC|Ensembl=ENSLOCG00000010411.1|UniProtKB=W5MWK6 W5MWK6 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003102.1|UniProtKB=W5M5J2 W5M5J2 PTHR48422:SF2 PROTEIN EVA-1 HOMOLOG B-RELATED PROTEIN EVA-1 HOMOLOG B LEPOC|Ensembl=ENSLOCG00000008665.1|UniProtKB=W5MQ93 W5MQ93 PTHR14206:SF4 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2-LIKE PROTEIN 1 cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003318.1|UniProtKB=W5M6C1 W5M6C1 PTHR11748:SF111 D-LACTATE DEHYDROGENASE D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;monocarboxylic acid catabolic process#GO:0072329 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003330.1|UniProtKB=W5M6C9 W5M6C9 PTHR24126:SF14 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANK_REP_REGION DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017174.1|UniProtKB=W5NKS7 W5NKS7 PTHR13800:SF6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012715.1|UniProtKB=W5N4U6 W5N4U6 RAP1GDS1 PTHR10957:SF2 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009904.1|UniProtKB=W5MUP9 W5MUP9 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005326.1|UniProtKB=W5MDF3 W5MDF3 PTHR31443:SF1 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 LEPOC|Ensembl=ENSLOCG00000013025.1|UniProtKB=W5N5Z3 W5N5Z3 PLXND1 PTHR22625:SF7 PLEXIN PLEXIN-D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;regulation of GTPase activity#GO:0043087;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of nervous system development#GO:0051962;endothelial cell migration#GO:0043542;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of neuron projection development#GO:0010975;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;cell migration#GO:0016477;positive regulation of multicellular organismal process#GO:0051240 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004455.1|UniProtKB=W5MAB6 W5MAB6 PTHR31671:SF2 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 2 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of biosynthetic process#GO:0009891;vacuole organization#GO:0007033;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;positive regulation of RNA metabolic process#GO:0051254;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016593.1|UniProtKB=W5NIN4 W5NIN4 PTHR23186:SF2 RETINOIC ACID-INDUCED PROTEIN 2 SINE OCULIS-BINDING PROTEIN HOMOLOG anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016054.1|UniProtKB=W5NGM1 W5NGM1 PTHR48092:SF10 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011112.1|UniProtKB=W5MZ45 W5MZ45 PTHR16451:SF7 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MAB-21-LIKE HHH_H2TH-LIKE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of mitochondrion organization#GO:0010821;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;positive regulation of developmental process#GO:0051094;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000012712.1|UniProtKB=W5N4T2 W5N4T2 PTHR35255:SF1 TRANSMEMBRANE PROTEIN 71 TRANSMEMBRANE PROTEIN 71 LEPOC|Ensembl=ENSLOCG00000010104.1|UniProtKB=W5MVK7 W5MVK7 PTHR23345:SF9 VITELLOGENIN-RELATED VITELLOGENIN-RELATED transporter activity#GO:0005215;lipid transporter activity#GO:0005319 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cellular process#GO:0009987;response to estradiol#GO:0032355 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000006908.1|UniProtKB=W5MIZ6 W5MIZ6 PTHR11394:SF47 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 40 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014579.1|UniProtKB=W5NBD2 W5NBD2 PTHR12306:SF9 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEC biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 LEPOC|Ensembl=ENSLOCG00000015484.1|UniProtKB=W5NEJ9 W5NEJ9 PTHR46462:SF2 UPSET, ISOFORM A INACTIVE HISTONE-LYSINE N-METHYLTRANSFERASE 2E protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;Rpd3L-Expanded complex#GO:0070210;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010721.1|UniProtKB=W5MXM6 W5MXM6 PTHR21324:SF7 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150C cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006556.1|UniProtKB=W5MHR0 W5MHR0 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017876.1|UniProtKB=W5NMX0 W5NMX0 PTHR24072:SF0 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOB GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 small GTPase#PC00208 Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;PDGF signaling pathway#P00047>Ras#P01154;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740 LEPOC|Ensembl=ENSLOCG00000000124.1|UniProtKB=W5LVH8 W5LVH8 PTHR13169:SF0 UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN UBIQUITIN-LIKE PROTEIN 3 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008531.1|UniProtKB=W5MPS4 W5MPS4 PTHR18945:SF764 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3E monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001020.1|UniProtKB=W5LYE1 W5LYE1 PTHR11782:SF38 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000008896.1|UniProtKB=W5MR22 W5MR22 PTHR12419:SF9 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 4 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of response to external stimulus#GO:0032101;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;regulation of metabolic process#GO:0019222 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002974.1|UniProtKB=W5M544 W5M544 PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE UDP-glucosyltransferase activity#GO:0035251;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017566.1|UniProtKB=W5NM12 W5NM12 C5AR2 PTHR24225:SF56 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008568.1|UniProtKB=W5MPW1 W5MPW1 PTHR15825:SF0 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003861.1|UniProtKB=W5M8A6 W5M8A6 PTHR44054:SF2 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000004941.1|UniProtKB=W5MC36 W5MC36 PTHR13073:SF0 BLOC-1 COMPLEX SUBUNIT 1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013490.1|UniProtKB=W5N7M3 W5N7M3 PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014212.1|UniProtKB=W5NA48 W5NA48 PTHR13768:SF23 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN syntaxin binding#GO:0019905;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;cellular component disassembly#GO:0022411;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component biogenesis#GO:0044087;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;protein-containing complex disassembly#GO:0032984;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;synaptic transmission, glutamatergic#GO:0035249 bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;cell junction#GO:0030054;SNARE complex#GO:0031201;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018362.1|UniProtKB=W5NPA4 W5NPA4 PTHR19290:SF53 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 23 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000011883.1|UniProtKB=W5N1U7 W5N1U7 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000009720.1|UniProtKB=W5MU13 W5MU13 PTHR46636:SF1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular metabolic process#GO:0031325;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000013469.1|UniProtKB=W5N7L0 W5N7L0 ZNF106 PTHR14435:SF2 ZINC FINGER PROTEIN 106 ZINC FINGER PROTEIN 106 LEPOC|Ensembl=ENSLOCG00000014016.1|UniProtKB=W5N9G9 W5N9G9 CRACD PTHR47574:SF3 CANCER-RELATED REGULATOR OF ACTIN DYNAMICS CAPPING PROTEIN-INHIBITING REGULATOR OF ACTIN DYNAMICS LEPOC|Ensembl=ENSLOCG00000007399.1|UniProtKB=W5MKS3 W5MKS3 OLA1 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein#PC00020;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005993.1|UniProtKB=W5MFT2 W5MFT2 PTHR46105:SF6 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010442.1|UniProtKB=W5MWP8 W5MWP8 PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000018133.1|UniProtKB=W5NNM5 W5NNM5 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001965.1|UniProtKB=W5M1M1 W5M1M1 PTHR24543:SF333 MULTICOPPER OXIDASE-RELATED EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006471.1|UniProtKB=W5MHF8 W5MHF8 PTHR13723:SF312 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015088.1|UniProtKB=W5ND60 W5ND60 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001320.1|UniProtKB=W5LZF4 W5LZF4 TINAGL1 PTHR12411:SF895 CYSTEINE PROTEASE FAMILY C1-RELATED SI:DKEY-158B13.1 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017255.1|UniProtKB=W5NL34 W5NL34 PTHR10015:SF185 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 2 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000018036.1|UniProtKB=W5NNC8 W5NNC8 PTHR15654:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 96 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000009729.1|UniProtKB=W5MU27 W5MU27 EIF3A PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017886.1|UniProtKB=W5NMY0 W5NMY0 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005721.1|UniProtKB=W5MEU7 W5MEU7 PTHR21228:SF59 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA processing#GO:0000963;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013005.1|UniProtKB=W5N5W2 W5N5W2 PTHR14338:SF4 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 2 protein binding#GO:0005515;SH3 domain binding#GO:0017124;binding#GO:0005488 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cytokine production#GO:0001819;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cytokine production#GO:0001817;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of ERBB signaling pathway#GO:1901184;positive regulation of RNA metabolic process#GO:0051254;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005127.1|UniProtKB=W5MCR1 W5MCR1 PTHR11486:SF26 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000015029.1|UniProtKB=W5ND04 W5ND04 PTHR11670:SF31 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER IRON-RESPONSIVE ELEMENT-BINDING PROTEIN 2 carbon-oxygen lyase activity#GO:0016835;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;hydro-lyase activity#GO:0016836;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;lyase activity#GO:0016829;mRNA binding#GO:0003729 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 LEPOC|Ensembl=ENSLOCG00000013283.1|UniProtKB=W5N6W4 W5N6W4 PTHR45760:SF1 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A39-RELATED localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011604.1|UniProtKB=W5N0U9 W5N0U9 TOB2 PTHR17537:SF3 TRANSDUCER OF ERBB2 TOB PROTEIN TOB2 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005305.1|UniProtKB=W5MDD8 W5MDD8 PTHR24304:SF1 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7A1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011775.1|UniProtKB=W5N1H1 W5N1H1 PTHR31837:SF3 CYTOCHROME B-245 CHAPERONE 1 CYTOCHROME B-245 CHAPERONE 1 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007086.1|UniProtKB=W5MJM1 W5MJM1 PTHR25466:SF2 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 LEPOC|Ensembl=ENSLOCG00000013142.1|UniProtKB=W5N6C7 W5N6C7 PTHR10605:SF7 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3B1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015606.1|UniProtKB=W5NF04 W5NF04 PTHR10529:SF341 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000152.1|UniProtKB=W5LVK9 W5LVK9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010815.1|UniProtKB=W5MXZ8 W5MXZ8 PTHR45875:SF1 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE N6AMT1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016154.1|UniProtKB=W5NGZ9 W5NGZ9 PTHR14949:SF32 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 WNT INHIBITORY FACTOR 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 anatomical structure development#GO:0048856;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010374.1|UniProtKB=W5MWG5 W5MWG5 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004908.1|UniProtKB=W5MBZ4 W5MBZ4 PTHR46309:SF1 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017779.1|UniProtKB=W5NMM4 W5NMM4 PTHR12365:SF8 SPROUTY PROTEIN SPROUTY HOMOLOG 2 negative regulation of cellular metabolic process#GO:0031324;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of small GTPase mediated signal transduction#GO:0051058;negative regulation of protein kinase activity#GO:0006469;regulation of MAP kinase activity#GO:0043405;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511;FGF signaling pathway#P00021>Spry#P00626 LEPOC|Ensembl=ENSLOCG00000012752.1|UniProtKB=W5N4Y1 W5N4Y1 PTHR15417:SF2 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;phosphatase inhibitor#PC00183 Nicotine pharmacodynamics pathway#P06587>PPP1R1B#P06589;Dopamine receptor mediated signaling pathway#P05912>DARPP-32#P05950 LEPOC|Ensembl=ENSLOCG00000018035.1|UniProtKB=W5NNC7 W5NNC7 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007853.1|UniProtKB=W5MMD2 W5MMD2 PTHR24356:SF150 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006758.1|UniProtKB=W5MIG2 W5MIG2 PTHR23503:SF54 SOLUTE CARRIER FAMILY 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014850.1|UniProtKB=W5NCC7 W5NCC7 PTHR13528:SF2 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010055.1|UniProtKB=W5MVA0 W5MVA0 PTHR24020:SF89 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXI) CHAIN-LIKE ISOFORM X1 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000015574.1|UniProtKB=W5NEW4 W5NEW4 PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014291.1|UniProtKB=W5NAD9 W5NAD9 PTHR12419:SF58 OTU DOMAIN CONTAINING PROTEIN UBIQUITINYL HYDROLASE 1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016274.1|UniProtKB=W5NHG3 W5NHG3 BBS10 PTHR14667:SF2 BARDET-BIEDL SYNDROME 10 PROTEIN BARDET-BIEDL SYNDROME 10 PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chaperone-mediated protein complex assembly#GO:0051131;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000010253.1|UniProtKB=W5MVZ2 W5MVZ2 PTHR24320:SF264 RETINOL DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER ON CHROMOSOME X dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004823.1|UniProtKB=W5MBM9 W5MBM9 PTHR24390:SF213 ZINC FINGER PROTEIN VASCULAR ENDOTHELIAL ZINC FINGER 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008520.1|UniProtKB=W5MPQ9 W5MPQ9 PTHR47535:SF2 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G NESPRIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of organelle localization#GO:0051656 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000011971.1|UniProtKB=W5N262 W5N262 PTHR46107:SF2 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000010368.1|UniProtKB=W5MWE7 W5MWE7 PTHR24214:SF6 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014240.1|UniProtKB=W5NA74 W5NA74 PTHR12801:SF57 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED APOPTOSIS-ENHANCING NUCLEASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000017713.1|UniProtKB=W5NMF9 W5NMF9 PTHR24399:SF21 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012731.1|UniProtKB=W5N4V7 W5N4V7 PTHR15143:SF0 TELETHONIN TELETHONIN structural constituent of muscle#GO:0008307;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;structural molecule activity#GO:0005198;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;detection of mechanical stimulus#GO:0050982;muscle organ development#GO:0007517;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;system process#GO:0003008;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;skeletal muscle contraction#GO:0003009;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;response to abiotic stimulus#GO:0009628;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;heart morphogenesis#GO:0003007;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle contraction#GO:0060048;cardiac muscle tissue development#GO:0048738;detection of stimulus#GO:0051606;cellular component organization#GO:0016043;nervous system process#GO:0050877;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to mechanical stimulus#GO:0009612;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;heart process#GO:0003015;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;sarcomere#GO:0030017;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;I band#GO:0031674;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002423.1|UniProtKB=W5M3B2 W5M3B2 PTHR32019:SF2 R3H DOMAIN-CONTAINING PROTEIN 4 R3H DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000018308.1|UniProtKB=W5NP50 W5NP50 PTHR24028:SF241 CADHERIN-87A PROTOCADHERIN 2 ALPHA A 1 PRECURSOR cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000005375.1|UniProtKB=W5MDP2 W5MDP2 PTHR10465:SF1 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle fusion#GO:0048284 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000015674.1|UniProtKB=W5NF86 W5NF86 PTHR10338:SF62 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H5 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015062.1|UniProtKB=W5ND29 W5ND29 PTHR24068:SF24 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D4 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000015060.1|UniProtKB=W5ND31 W5ND31 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG LEPOC|Ensembl=ENSLOCG00000016723.1|UniProtKB=W5NJ56 W5NJ56 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001612.1|UniProtKB=W5M0F0 W5M0F0 PTHR14453:SF101 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017504.1|UniProtKB=W5NLV0 W5NLV0 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015404.1|UniProtKB=W5NE92 W5NE92 PTHR45644:SF8 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED OUTER MITOCHONDRIAL TRANSMEMBRANE HELIX TRANSLOCASE localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein localization to membrane#GO:0072657;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000014160.1|UniProtKB=W5N9Y4 W5N9Y4 PTHR11848:SF125 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-1 PROPROTEIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;regulation of cell population proliferation#GO:0042127;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778 LEPOC|Ensembl=ENSLOCG00000017620.1|UniProtKB=W5NM66 W5NM66 PTHR18884:SF128 SEPTIN SI:CH211-282J17.12-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017637.1|UniProtKB=W5NM83 W5NM83 PTHR22750:SF52 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE-1-PHOSPHATE RECEPTOR 3A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005740.1|UniProtKB=W5MEX4 W5MEX4 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of response to stress#GO:0080134;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular response to stress#GO:0080135;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012091.1|UniProtKB=W5N2N0 W5N2N0 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN 4-RELATED microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000016600.1|UniProtKB=W5NIQ6 W5NIQ6 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 LEPOC|Ensembl=ENSLOCG00000003197.1|UniProtKB=W5M5X4 W5M5X4 PTHR24306:SF4 FAMILY NOT NAMED PROSTACYCLIN SYNTHASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000004350.1|UniProtKB=W5M9Z0 W5M9Z0 PTHR44942:SF9 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN NOVEL PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000014927.1|UniProtKB=W5NCM1 W5NCM1 PTHR47979:SF69 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39B GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;myosin binding#GO:0017022;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003435.1|UniProtKB=W5M6R3 W5M6R3 PTHR21055:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000004270.1|UniProtKB=W5M9P6 W5M9P6 PTHR19370:SF108 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000018013.1|UniProtKB=W5NNA5 W5NNA5 PTHR22750:SF47 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Endogenous cannabinoid signaling#P05730>CB1#P05743 LEPOC|Ensembl=ENSLOCG00000013180.1|UniProtKB=W5N6I0 W5N6I0 SECISBP2L PTHR13284:SF10 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2-LIKE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001473.1|UniProtKB=W5M067 W5M067 COL16A1 PTHR24023:SF372 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVI) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000010406.1|UniProtKB=W5MWK0 W5MWK0 PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017686.1|UniProtKB=W5NMD2 W5NMD2 PTHR40472:SF11 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 3-RELATED LEPOC|Ensembl=ENSLOCG00000009146.1|UniProtKB=W5MRZ3 W5MRZ3 PTHR42904:SF6 NUDIX HYDROLASE, NUDC SUBFAMILY NAD-CAPPED RNA HYDROLASE NUDT12 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007437.1|UniProtKB=W5MKW3 W5MKW3 PTHR11753:SF19 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000012648.1|UniProtKB=W5N4K9 W5N4K9 PTHR24006:SF672 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001486.1|UniProtKB=W5M003 W5M003 PTHR11010:SF107 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED DIPEPTIDYL PEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015846.1|UniProtKB=W5NFU9 W5NFU9 PTHR21020:SF0 ZINC FINGER PROTEIN 800 ZINC FINGER PROTEIN 800 LEPOC|Ensembl=ENSLOCG00000012962.1|UniProtKB=W5N5Q5 W5N5Q5 FSD2 PTHR24099:SF6 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001778.1|UniProtKB=W5M153 W5M153 PTHR10574:SF444 NETRIN/LAMININ-RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000007837.1|UniProtKB=W5MMA5 W5MMA5 PTHR11727:SF7 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE-RELATED catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000018353.1|UniProtKB=W5NP95 W5NP95 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014525.1|UniProtKB=W5NB67 W5NB67 PTHR13793:SF85 PHD FINGER PROTEINS PEREGRIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011609.1|UniProtKB=W5N0V7 W5N0V7 PTHR13064:SF1 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER PROTON-TRANSPORTING V-TYPE ATPASE COMPLEX ASSEMBLY REGULATOR TMEM9 LEPOC|Ensembl=ENSLOCG00000004235.1|UniProtKB=W5M9K7 W5M9K7 PTHR21331:SF2 BRCA1-ASSOCIATED ATM ACTIVATOR 1 BRCA1-ASSOCIATED ATM ACTIVATOR 1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009186.1|UniProtKB=W5MS45 W5MS45 PTHR24412:SF451 KELCH PROTEIN KELCH-LIKE PROTEIN 20 scaffold/adaptor protein#PC00226 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 LEPOC|Ensembl=ENSLOCG00000008669.1|UniProtKB=W5MQ82 W5MQ82 PTHR47403:SF2 LOC100145250 PROTEIN N-ACETYLTRANSFERASE 16,-LIKE LEPOC|Ensembl=ENSLOCG00000000846.1|UniProtKB=W5LXU2 W5LXU2 PTHR11200:SF117 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 negative regulation of cellular metabolic process#GO:0031324;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;glycerolipid metabolic process#GO:0046486;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;phospholipid dephosphorylation#GO:0046839;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;phosphatidylinositol dephosphorylation#GO:0046856;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell leading edge#GO:0031252;endomembrane system#GO:0012505;ruffle#GO:0001726;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000012000.1|UniProtKB=W5N298 W5N298 PTHR15924:SF9 CLE RNA TRANSCRIPTION, TRANSLATION AND TRANSPORT FACTOR PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000011746.1|UniProtKB=W5N1D3 W5N1D3 PTHR24206:SF95 OS06G0237300 PROTEIN CYTOSKELETON-ASSOCIATED LIM DOMAIN PROTEIN-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015711.1|UniProtKB=W5NFD3 W5NFD3 PTHR11839:SF1 UDP/ADP-SUGAR PYROPHOSPHATASE ADP-SUGAR PYROPHOSPHATASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 pyrophosphatase#PC00196 LEPOC|Ensembl=ENSLOCG00000018322.1|UniProtKB=W5NP64 W5NP64 PTHR20961:SF38 GLYCOSYLTRANSFERASE PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001411.1|UniProtKB=W5LZQ4 W5LZQ4 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 preribosome, small subunit precursor#GO:0030688;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000006772.1|UniProtKB=W5MIG8 W5MIG8 FBXO39 PTHR10706:SF160 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 39 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014675.1|UniProtKB=W5NBQ8 W5NBQ8 PTHR12552:SF2 OLIGOPHRENIN 1 OLIGOPHRENIN-1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000006356.1|UniProtKB=W5MH18 W5MH18 PTHR11599:SF144 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA-TYPE 8 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000006922.1|UniProtKB=W5MJ19 W5MJ19 PTHR11347:SF108 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoric diester hydrolase activity#GO:0008081;transmembrane transporter binding#GO:0044325;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000016380.1|UniProtKB=W5NHX1 W5NHX1 PTHR24093:SF245 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 1 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003242.1|UniProtKB=W5M623 W5M623 PTHR24251:SF47 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN 2 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002065.1|UniProtKB=W5M1Y6 W5M1Y6 PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015699.1|UniProtKB=W5NFB6 W5NFB6 PTHR16058:SF4 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011974.1|UniProtKB=W5N265 W5N265 PTHR18966:SF382 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated channel activity#GO:0022832;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 signal transduction#GO:0007165;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of postsynaptic membrane potential#GO:0060078;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 LEPOC|Ensembl=ENSLOCG00000009401.1|UniProtKB=W5MSV8 W5MSV8 PTHR22918:SF1 SEMINAL PLASMA PROTEIN FIBRONECTIN TYPE-II DOMAIN-CONTAINING PROTEIN heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011467.1|UniProtKB=W5N0E9 W5N0E9 RASGEF1A PTHR23113:SF172 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1A nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016646.1|UniProtKB=W5NIV4 W5NIV4 PTHR11727:SF13 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;aromatic compound biosynthetic process#GO:0019438;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000012617.1|UniProtKB=W5N4H7 W5N4H7 PTHR23036:SF163 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011331.1|UniProtKB=W5MZX2 W5MZX2 WDR77 PTHR46853:SF1 METHYLOSOME PROTEIN 50 METHYLOSOME PROTEIN 50 cytoplasm#GO:0005737;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000018038.1|UniProtKB=W5NND0 W5NND0 PTHR24248:SF25 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2C ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000009111.1|UniProtKB=W5MRV2 W5MRV2 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000006602.1|UniProtKB=W5MHW7 W5MHW7 PTHR11347:SF34 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;cellular anatomical entity#GO:0110165;cell body#GO:0044297;neuronal cell body#GO:0043025 phosphodiesterase#PC00185 CCKR signaling map#P06959>PDE#P07161 LEPOC|Ensembl=ENSLOCG00000012222.1|UniProtKB=W5N323 W5N323 PTHR21320:SF3 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009442.1|UniProtKB=W5MT13 W5MT13 PTHR24270:SF47 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 12 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000008942.1|UniProtKB=W5MR83 W5MR83 PTHR12081:SF44 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 p53 pathway feedback loops 2#P04398>E2F-1#P04652;p53 pathway#P00059>E2F-1#P04627;Cell cycle#P00013>E2F#P00488 LEPOC|Ensembl=ENSLOCG00000014402.1|UniProtKB=W5NAS0 W5NAS0 PTHR24083:SF45 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;small molecule binding#GO:0036094;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;anion binding#GO:0043168 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010042.1|UniProtKB=W5MV71 W5MV71 TCP11X2 PTHR12832:SF14 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11 HOMOLOG regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;protein kinase A signaling#GO:0010737;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;signaling#GO:0023052 acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;sperm flagellum#GO:0036126;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;motile cilium#GO:0031514;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;secretory vesicle#GO:0099503 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009193.1|UniProtKB=W5MS51 W5MS51 PTHR47966:SF66 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSINOGEN C hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007696.1|UniProtKB=W5MLU6 W5MLU6 PTHR14139:SF5 CALSYNTENIN CALSYNTENIN-3 regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of trans-synaptic signaling#GO:0099177;regulation of cell junction assembly#GO:1901888;positive regulation of synaptic transmission#GO:0050806;regulation of synapse structure or activity#GO:0050803;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003829.1|UniProtKB=W5M864 W5M864 PTHR21292:SF12 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012665.1|UniProtKB=W5N4N1 W5N4N1 NT5C3B PTHR13045:SF15 5'-NUCLEOTIDASE 7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000004441.1|UniProtKB=W5MAA9 W5MAA9 PTHR11269:SF9 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to abiotic stimulus#GO:0009628;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01499 LEPOC|Ensembl=ENSLOCG00000011525.1|UniProtKB=W5N0K0 W5N0K0 MCUR1 PTHR14360:SF11 PROTEIN FMP32, MITOCHONDRIAL MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009216.1|UniProtKB=W5MS82 W5MS82 PTHR45622:SF73 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC4-LIKE ISOFORM X1-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018298.1|UniProtKB=W5NP40 W5NP40 PTHR15284:SF6 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN HYPOTHETICAL LOC799271-RELATED circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000010992.1|UniProtKB=W5MYN3 W5MYN3 PTHR45678:SF12 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER SLC25A13, MITOCHONDRIAL L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;acidic amino acid transmembrane transporter activity#GO:0015172 cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;respiratory electron transport chain#GO:0022904;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017285.1|UniProtKB=W5NL74 W5NL74 C6orf58 PTHR18820:SF1 LEG1 PROTEIN LEG1 HOMOLOG extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000015537.1|UniProtKB=W5NER7 W5NER7 PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009767.1|UniProtKB=W5MU80 W5MU80 PTHR10408:SF6 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;sterol binding#GO:0032934;O-acyltransferase activity#GO:0008374;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;lipid transport#GO:0006869;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;cholesterol transport#GO:0030301;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;cholesterol efflux#GO:0033344;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000016772.1|UniProtKB=W5NJC2 W5NJC2 PTHR10515:SF0 THYMIDINE PHOSPHORYLASE THYMIDINE PHOSPHORYLASE cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine phosphorylase#P03148;Salvage pyrimidine deoxyribonucleotides#P02774>Uracil phosphorylase#P03145;Pyrimidine Metabolism#P02771>Nucleoside Phosphorylase#P03126 LEPOC|Ensembl=ENSLOCG00000013135.1|UniProtKB=W5N6B8 W5N6B8 PTHR10342:SF69 ARYLSULFATASE ARYLSULFATASE J LEPOC|Ensembl=ENSLOCG00000002445.1|UniProtKB=W5M3B1 W5M3B1 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE LEPOC|Ensembl=ENSLOCG00000002941.1|UniProtKB=W5M508 W5M508 PTHR15660:SF1 BRISC AND BRCA1-A COMPLEX MEMBER 1 BRISC AND BRCA1-A COMPLEX MEMBER 1 LEPOC|Ensembl=ENSLOCG00000001318.1|UniProtKB=W5LZE3 W5LZE3 PTHR13832:SF535 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1E negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015527.1|UniProtKB=W5NEQ2 W5NEQ2 PTHR10751:SF105 GUANYLATE BINDING PROTEIN CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8 ISOFORM X1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001038.1|UniProtKB=W5LYF4 W5LYF4 PTHR17103:SF11 NEUREXOPHILIN NEUREXOPHILIN-2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009182.1|UniProtKB=W5MS38 W5MS38 PTHR12263:SF5 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 1 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 ATP synthase#PC00002;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014167.1|UniProtKB=W5N9Z3 W5N9Z3 PTHR24240:SF65 OPSIN NOVEL OPSIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012851.1|UniProtKB=W5N5A9 W5N5A9 PTHR10996:SF137 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001593.1|UniProtKB=W5M0C2 W5M0C2 C20orf27 PTHR13287:SF2 ADIPOSE-SECRETED SIGNALING PROTEIN ADIPOSE-SECRETED SIGNALING PROTEIN LEPOC|Ensembl=ENSLOCG00000010200.1|UniProtKB=W5MVT1 W5MVT1 PTHR31655:SF0 PROTEIN FAM78A PROTEIN FAM78B LEPOC|Ensembl=ENSLOCG00000009157.1|UniProtKB=W5MS02 W5MS02 PTHR11245:SF2 STANNIOCALCIN STANNIOCALCIN-2 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000006140.1|UniProtKB=W5MGA9 W5MGA9 SMCO1 PTHR35979:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009846.1|UniProtKB=W5MUH3 W5MUH3 HYCC2 PTHR31220:SF3 HYCCIN RELATED HYCCIN 2 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009423.1|UniProtKB=W5MSZ1 W5MSZ1 PTHR15427:SF28 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014685.1|UniProtKB=W5NBR6 W5NBR6 PTHR19282:SF48 TETRASPANIN TETRASPANIN-3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012954.1|UniProtKB=W5N5P1 W5N5P1 PTHR12582:SF7 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000001454.1|UniProtKB=W5LZW9 W5LZW9 EPB41L1 PTHR23280:SF24 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Nicotine pharmacodynamics pathway#P06587>EPB41L1#P06599;Dopamine receptor mediated signaling pathway#P05912>EPB41L1#P05953;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 LEPOC|Ensembl=ENSLOCG00000007059.1|UniProtKB=W5MJI7 W5MJI7 PTHR21538:SF27 ANILLIN/RHOTEKIN RTKN ANILLIN cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring assembly#GO:0000915;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 actomyosin contractile ring#GO:0005826;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell division site#GO:0032153;contractile ring#GO:0070938;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003105.1|UniProtKB=W5M5K0 W5M5K0 INSC PTHR21386:SF0 INSCUTEABLE PROTEIN INSCUTEABLE HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;protein localization#GO:0008104;localization#GO:0051179;establishment of mitotic spindle orientation#GO:0000132;establishment of mitotic spindle localization#GO:0040001;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;cell cycle#GO:0007049 cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007183.1|UniProtKB=W5MJY8 W5MJY8 PTHR24068:SF211 UBIQUITIN-CONJUGATING ENZYME E2 AKT-INTERACTING PROTEIN ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein K63-linked ubiquitination#GO:0070534;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006261.1|UniProtKB=W5MGQ6 W5MGQ6 PJVK PTHR16399:SF10 GASDERMIN PEJVAKIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016167.1|UniProtKB=W5NH15 W5NH15 PTHR46227:SF3 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 protein localization to plasma membrane#GO:0072659;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein-containing complex localization#GO:0031503 LEPOC|Ensembl=ENSLOCG00000007201.1|UniProtKB=W5MK07 W5MK07 PTHR11422:SF6 T-CELL SURFACE GLYCOPROTEIN CD4 HEMICENTIN-1 ISOFORM X1 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003223.1|UniProtKB=W5M5Z9 W5M5Z9 CSTB PTHR11414:SF21 CYSTATIN FAMILY MEMBER CYSTATIN 14A, TANDEM DUPLICATE 1-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013381.1|UniProtKB=W5N784 W5N784 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015183.1|UniProtKB=W5NDH2 W5NDH2 PTHR21324:SF11 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1 regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;regulation of cellular catabolic process#GO:0031329;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010016.1|UniProtKB=W5MV47 W5MV47 PTHR28441:SF2 PROTEIN FAM91A1 PROTEIN FAM91A1 LEPOC|Ensembl=ENSLOCG00000001407.1|UniProtKB=W5LZP5 W5LZP5 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012239.1|UniProtKB=W5N347 W5N347 PTHR10497:SF0 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014048.1|UniProtKB=W5N9K5 W5N9K5 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED TRANSMEMBRANE PROTEIN 165 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 LEPOC|Ensembl=ENSLOCG00000002092.1|UniProtKB=W5M220 W5M220 PTHR46809:SF1 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003730.1|UniProtKB=W5M7T8 W5M7T8 PTHR13914:SF0 PROLINE OXIDASE PROLINE DEHYDROGENASE 1, MITOCHONDRIAL oxidase#PC00175;oxidoreductase#PC00176 Huntington disease#P00029>Proline oxidase#G01529 LEPOC|Ensembl=ENSLOCG00000017639.1|UniProtKB=W5NM85 W5NM85 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000011196.1|UniProtKB=W5MZE4 W5MZE4 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003423.1|UniProtKB=W5M6Q7 W5M6Q7 C11orf16 PTHR14343:SF3 VWFA DOMAIN-CONTAINING PROTEIN SIMILAR TO PREDICTED GENE ICRFP703B1614Q5.5 LEPOC|Ensembl=ENSLOCG00000005968.1|UniProtKB=W5MFR2 W5MFR2 PTHR47448:SF3 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007055.1|UniProtKB=W5MJH8 W5MJH8 PTHR23239:SF366 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 47 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001752.1|UniProtKB=W5M0W7 W5M0W7 PTHR15140:SF6 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007521.1|UniProtKB=W5ML80 W5ML80 MTFP1 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fission#GO:0000266 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009033.1|UniProtKB=W5MRK7 W5MRK7 PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005162.1|UniProtKB=W5MCV6 W5MCV6 PTHR24241:SF4 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018011.1|UniProtKB=W5NNA3 W5NNA3 HTR1E PTHR24247:SF33 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1E signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 LEPOC|Ensembl=ENSLOCG00000010673.1|UniProtKB=W5MXH4 W5MXH4 PTHR23255:SF61 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-1 signaling receptor activity#GO:0038023;SMAD binding#GO:0046332;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;system development#GO:0048731;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000004555.1|UniProtKB=W5MAN8 W5MAN8 PTHR24064:SF673 SOLUTE CARRIER FAMILY 22 MEMBER SYNAPTIC VESICLE 2-RELATED PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012685.1|UniProtKB=W5N4Q0 W5N4Q0 PTHR24103:SF588 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 8 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003936.1|UniProtKB=W5M8K3 W5M8K3 PTHR11640:SF51 NEPHRIN KIN OF IRRE-LIKE PROTEIN 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004742.1|UniProtKB=W5MBE6 W5MBE6 PTHR31826:SF3 NICALIN BOS COMPLEX SUBUNIT NCLN biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008940.1|UniProtKB=W5MR82 W5MR82 PTHR11588:SF251 TUBULIN TUBULIN ALPHA-1B CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 LEPOC|Ensembl=ENSLOCG00000009236.1|UniProtKB=W5MSA2 W5MSA2 PTHR22913:SF7 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosaminoglycan metabolic process#GO:0030203;cellular component assembly#GO:0022607;carbohydrate biosynthetic process#GO:0016051;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;polysaccharide metabolic process#GO:0005976;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010184.1|UniProtKB=W5MVQ8 W5MVQ8 PTHR47888:SF1 UPF0730 PROTEIN ENCODED BY LINC00643-RELATED SERTA DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010701.1|UniProtKB=W5MXK3 W5MXK3 PTHR12198:SF9 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000734.1|UniProtKB=W5LXF4 W5LXF4 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000017272.1|UniProtKB=W5NL55 W5NL55 PTHR20859:SF86 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 LEPOC|Ensembl=ENSLOCG00000015475.1|UniProtKB=W5NEI5 W5NEI5 PTHR47979:SF73 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;regulation of biological process#GO:0050789;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;transport#GO:0006810;biological regulation#GO:0065007;regulation of localization#GO:0032879;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002282.1|UniProtKB=W5M2Q4 W5M2Q4 PTHR24060:SF162 METABOTROPIC GLUTAMATE RECEPTOR TASTE RECEPTOR TYPE 1 MEMBER 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008576.1|UniProtKB=W5MPX0 W5MPX0 PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002254.1|UniProtKB=W5M2L9 W5M2L9 PTHR10699:SF16 NEUROMODULIN SPERM SURFACE PROTEIN SP17 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000008684.1|UniProtKB=W5MQA3 W5MQA3 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017143.1|UniProtKB=W5NKM7 W5NKM7 PTHR46806:SF1 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017801.1|UniProtKB=W5NMP6 W5NMP6 TASL PTHR14889:SF3 RCG36411 TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME lysosome organization#GO:0007040;regulation of intracellular pH#GO:0051453;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular component organization#GO:0016043;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular component organization or biogenesis#GO:0071840;regulation of pH#GO:0006885;vacuole organization#GO:0007033;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641;lytic vacuole organization#GO:0080171 LEPOC|Ensembl=ENSLOCG00000002239.1|UniProtKB=W5M2J1 W5M2J1 PTHR21348:SF2 FAMILY NOT NAMED SULFIREDOXIN-1 LEPOC|Ensembl=ENSLOCG00000010245.1|UniProtKB=W5MW07 W5MW07 PTHR11453:SF14 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009414.1|UniProtKB=W5MSZ0 W5MSZ0 PTHR46728:SF1 AN1-TYPE ZINC FINGER PROTEIN 4 AN1-TYPE ZINC FINGER PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000002710.1|UniProtKB=W5M487 W5M487 PTHR13847:SF287 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015874.1|UniProtKB=W5NFY9 W5NFY9 PTHR13691:SF73 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017738.1|UniProtKB=W5NMI3 W5NMI3 PTHR45752:SF11 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8D organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;amino acid transport#GO:0006865;monoatomic anion transmembrane transport#GO:0098656;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;nucleobase-containing compound transport#GO:0015931;C4-dicarboxylate transport#GO:0015740;monoatomic anion transport#GO:0006820;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;carbohydrate derivative transport#GO:1901264;import into cell#GO:0098657 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014310.1|UniProtKB=W5NAH5 W5NAH5 RASGRF1 PTHR23113:SF193 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017342.1|UniProtKB=W5NLD8 W5NLD8 TMEM250 PTHR48431:SF1 TRANSMEMBRANE PROTEIN 250 TRANSMEMBRANE PROTEIN 250 LEPOC|Ensembl=ENSLOCG00000007940.1|UniProtKB=W5MMN1 W5MMN1 PTHR46907:SF2 HEAT SHOCK PROTEIN BETA-7-RELATED HEAT SHOCK PROTEIN BETA-7 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004818.1|UniProtKB=W5MBP6 W5MBP6 DRAXIN PTHR28610:SF1 DRAXIN DRAXIN cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012481.1|UniProtKB=W5N405 W5N405 PTHR12872:SF1 ALPHA-N-ACETYLGLUCOSAMINIDASE ALPHA-N-ACETYLGLUCOSAMINIDASE LEPOC|Ensembl=ENSLOCG00000014524.1|UniProtKB=W5NB65 W5NB65 PTHR23348:SF42 PERIAXIN/AHNAK PERIAXIN neurogenesis#GO:0022008;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;plasma membrane organization#GO:0007009;developmental process#GO:0032502;endomembrane system organization#GO:0010256;gliogenesis#GO:0042063;peripheral nervous system development#GO:0007422;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;myelination#GO:0042552 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017315.1|UniProtKB=W5NLB1 W5NLB1 PTHR10960:SF0 V D J RECOMBINATION-ACTIVATING PROTEIN 2 V(D)J RECOMBINATION-ACTIVATING PROTEIN 2 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;V(D)J recombination#GO:0033151;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;immune system process#GO:0002376;system development#GO:0048731;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;somatic cell DNA recombination#GO:0016444;nitrogen compound metabolic process#GO:0006807;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;somatic diversification of immune receptors#GO:0002200;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993 LEPOC|Ensembl=ENSLOCG00000010740.1|UniProtKB=W5MXQ0 W5MXQ0 PTHR44888:SF1 HEPACAM FAMILY MEMBER 2-RELATED HEPACAM FAMILY MEMBER 2 LEPOC|Ensembl=ENSLOCG00000016770.1|UniProtKB=W5NJB9 W5NJB9 PTHR21580:SF28 SHIPPO-1-RELATED BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001975.1|UniProtKB=W5M1M9 W5M1M9 PTHR24233:SF0 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011853.1|UniProtKB=W5N1R6 W5N1R6 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016023.1|UniProtKB=W5NGI4 W5NGI4 PTHR11036:SF25 SEMAPHORIN SEMAPHORIN-3C molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008663.1|UniProtKB=W5MQ80 W5MQ80 PRDM6 PTHR16515:SF22 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM6-RELATED regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016417.1|UniProtKB=W5NI21 W5NI21 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;microtubule organizing center#GO:0005815;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;cytoplasmic dynein complex#GO:0005868 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007959.1|UniProtKB=W5MMT1 W5MMT1 PTHR46029:SF3 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 LEPOC|Ensembl=ENSLOCG00000016290.1|UniProtKB=W5NHK3 W5NHK3 PTHR11339:SF225 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN-LIKE PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000018004.1|UniProtKB=W5NN96 W5NN96 PTHR11537:SF171 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY F MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007878.1|UniProtKB=W5MMF3 W5MMF3 PTHR48225:SF7 HORMA DOMAIN-CONTAINING PROTEIN 1 MEIOSIS-SPECIFIC PROTEIN HOP1 LEPOC|Ensembl=ENSLOCG00000004817.1|UniProtKB=W5MBM4 W5MBM4 PTHR24215:SF1 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 3 structural constituent of muscle#GO:0008307;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;nucleus#GO:0005634;Z disc#GO:0030018;intracellular membrane-bounded organelle#GO:0043231;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011318.1|UniProtKB=W5MZV3 W5MZV3 FANCM PTHR14025:SF20 FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER FANCONI ANEMIA GROUP M PROTEIN DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008276.1|UniProtKB=W5MNU2 W5MNU2 PTHR21181:SF13 FAMILY NOT NAMED NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6 LEPOC|Ensembl=ENSLOCG00000002277.1|UniProtKB=W5M2Q1 W5M2Q1 PTHR19378:SF0 GOLGIN- RELATED HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010400.1|UniProtKB=W5MWJ7 W5MWJ7 PTHR10201:SF26 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-16 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;skeletal system development#GO:0001501;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000006910.1|UniProtKB=W5MIZ8 W5MIZ8 PTHR20974:SF2 UPF0585 PROTEIN CG18661 METHYLTRANSFERASE-LIKE 26 LEPOC|Ensembl=ENSLOCG00000011390.1|UniProtKB=W5N043 W5N043 PTHR45011:SF1 DAP3-BINDING CELL DEATH ENHANCER 1 DAP3-BINDING CELL DEATH ENHANCER 1 LEPOC|Ensembl=ENSLOCG00000006055.1|UniProtKB=W5MG07 W5MG07 PTHR23333:SF24 UBX DOMAIN CONTAINING PROTEIN NSFL1 COFACTOR P47 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;membrane organization#GO:0061024;protein catabolic process#GO:0030163;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;membrane assembly#GO:0071709;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear membrane organization#GO:0071763;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;nuclear envelope organization#GO:0006998;autophagy#GO:0006914 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013740.1|UniProtKB=W5N8I9 W5N8I9 PTHR48105:SF19 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN-DISULFIDE REDUCTASE protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007907.1|UniProtKB=W5MMJ4 W5MMJ4 PTHR11575:SF48 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012827.1|UniProtKB=W5N577 W5N577 PTHR46614:SF1 MORN REPEAT-CONTAINING PROTEIN 4 MORN REPEAT-CONTAINING PROTEIN 4 response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611 cell projection#GO:0042995;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006384.1|UniProtKB=W5MH51 W5MH51 KIF18A PTHR24115:SF372 KINESIN-RELATED KINESIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515 nuclear chromosome segregation#GO:0098813;protein-containing complex disassembly#GO:0032984;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;microtubule depolymerization#GO:0007019;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005234.1|UniProtKB=W5MD48 W5MD48 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006224.1|UniProtKB=W5MGM4 W5MGM4 PTHR13318:SF169 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 9 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006903.1|UniProtKB=W5MIY9 W5MIY9 PTHR23036:SF109 CYTOKINE RECEPTOR LEPTIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005019.1|UniProtKB=W5MCD3 W5MCD3 PTHR44167:SF32 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED CBL-INTERACTING SERINE_THREONINE-PROTEIN KINASE 25-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;mitotic DNA damage checkpoint signaling#GO:0044773 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016273.1|UniProtKB=W5NHG4 W5NHG4 ASB3 PTHR24123:SF140 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT AND SOCS BOX CONTAINING 15 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005203.1|UniProtKB=W5MD32 W5MD32 PTHR11640:SF148 NEPHRIN CD166 ANTIGEN HOMOLOG A cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008433.1|UniProtKB=W5MPE4 W5MPE4 PTHR46890:SF29 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000016714.1|UniProtKB=W5NJ42 W5NJ42 PTHR28603:SF1 TRANSMEMBRANE PROTEIN 243 TRANSMEMBRANE PROTEIN 243 LEPOC|Ensembl=ENSLOCG00000014930.1|UniProtKB=W5NCM2 W5NCM2 PTHR24073:SF897 DRAB5-RELATED RAS-RELATED PROTEIN RAB GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016398.1|UniProtKB=W5NHZ1 W5NHZ1 PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004656.1|UniProtKB=W5MB47 W5MB47 SGK3 PTHR24351:SF197 RIBOSOMAL PROTEIN S6 KINASE SERUM_GLUCOCORTICOID REGULATED KINASE FAMILY MEMBER 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004151.1|UniProtKB=W5M9B2 W5M9B2 PTHR14002:SF59 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001530.1|UniProtKB=W5M063 W5M063 PTHR12424:SF4 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005067.1|UniProtKB=W5MCJ2 W5MCJ2 PTHR10177:SF67 CYCLINS G1_S-SPECIFIC CYCLIN-D1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 CCKR signaling map#P06959>CCND1#G06986;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;CCKR signaling map#P06959>CCND1#G07280;PI3 kinase pathway#P00048>Cyclin d#G01546;Cell cycle#P00013>Cyclin D#P00484 LEPOC|Ensembl=ENSLOCG00000015506.1|UniProtKB=W5NEM2 W5NEM2 PTHR15493:SF8 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 5 negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of cell cycle process#GO:0010948;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010386.1|UniProtKB=W5MWH3 W5MWH3 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013406.1|UniProtKB=W5N7C3 W5N7C3 SEC14L1 PTHR23324:SF51 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009791.1|UniProtKB=W5MUB0 W5MUB0 PTHR15827:SF2 CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN Cell cycle#P00013>Cdk2#P00485 LEPOC|Ensembl=ENSLOCG00000011178.1|UniProtKB=W5MZF1 W5MZF1 PTHR24115:SF893 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018350.1|UniProtKB=W5NP92 W5NP92 PTHR23349:SF64 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016466.1|UniProtKB=W5NI82 W5NI82 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007297.1|UniProtKB=W5MKC7 W5MKC7 PTHR15192:SF15 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of growth#GO:0040008;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558 LEPOC|Ensembl=ENSLOCG00000003097.1|UniProtKB=W5M5I7 W5M5I7 PTHR33198:SF20 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008949.1|UniProtKB=W5MR94 W5MR94 QTRT1 PTHR43530:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004466.1|UniProtKB=W5MAG5 W5MAG5 UNC13B PTHR10480:SF8 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG B syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;transport#GO:0006810;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;establishment of organelle localization#GO:0051656;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;vesicle localization#GO:0051648;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;synaptic transmission, glutamatergic#GO:0035249;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;neuromuscular junction#GO:0031594;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Munc13#P05773 LEPOC|Ensembl=ENSLOCG00000011038.1|UniProtKB=W5MYT4 W5MYT4 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016986.1|UniProtKB=W5NK40 W5NK40 PTHR10663:SF333 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PROTEIN MON2 HOMOLOG guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001673.1|UniProtKB=W5M0N9 W5M0N9 PTHR45766:SF3 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009091.1|UniProtKB=W5MRT8 W5MRT8 PTHR22957:SF536 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000017517.1|UniProtKB=W5NLW3 W5NLW3 PTHR10489:SF735 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 10 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000006399.1|UniProtKB=W5MH69 W5MH69 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011385.1|UniProtKB=W5N036 W5N036 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 40S RIBOSOMAL PROTEIN S29 cation binding#GO:0043169;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005533.1|UniProtKB=W5ME71 W5ME71 PTHR12127:SF4 MUCOLIPIN MUCOLIPIN-2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007019.1|UniProtKB=W5MJD5 W5MJD5 PTHR45946:SF3 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-A1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000484.1|UniProtKB=W5LWM5 W5LWM5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011916.1|UniProtKB=W5N1Z0 W5N1Z0 PTHR11309:SF34 FRIZZLED FRIZZLED-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000009277.1|UniProtKB=W5MSF6 W5MSF6 KCNRG PTHR14499:SF5 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL REGULATORY PROTEIN regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;negative regulation of transport#GO:0051051;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000322.1|UniProtKB=W5LW41 W5LW41 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015995.1|UniProtKB=W5NGD9 W5NGD9 OTOR PTHR47146:SF1 OTORAPLIN OTORAPLIN system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;skeletal system development#GO:0001501;cellular process#GO:0009987;tissue development#GO:0009888 LEPOC|Ensembl=ENSLOCG00000007125.1|UniProtKB=W5MJR6 W5MJR6 PTHR11422:SF12 T-CELL SURFACE GLYCOPROTEIN CD4 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;MHC protein binding#GO:0042287;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;lymphocyte activation#GO:0046649;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004544.1|UniProtKB=W5MAP3 W5MAP3 PTHR15606:SF4 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004876.1|UniProtKB=W5MBV2 W5MBV2 PTHR13869:SF19 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 1 cell surface#GO:0009986;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010544.1|UniProtKB=W5MX11 W5MX11 PTHR10476:SF72 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004260.1|UniProtKB=W5M9N6 W5M9N6 PTHR45664:SF12 PROTEIN ZERKNUELLT 1-RELATED PANCREAS_DUODENUM HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008932.1|UniProtKB=W5MR69 W5MR69 PTHR24200:SF7 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013242.1|UniProtKB=W5N6Q4 W5N6Q4 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 LEPOC|Ensembl=ENSLOCG00000011182.1|UniProtKB=W5MZC8 W5MZC8 PTHR22937:SF65 E3 UBIQUITIN-PROTEIN LIGASE RNF165 E3 UBIQUITIN-PROTEIN LIGASE ARK2C transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003244.1|UniProtKB=W5M624 W5M624 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mediator complex#GO:0016592;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016099.1|UniProtKB=W5NGS5 W5NGS5 PTHR24248:SF16 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000002167.1|UniProtKB=W5M2D2 W5M2D2 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004915.1|UniProtKB=W5MC03 W5MC03 PTHR19860:SF16 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000013616.1|UniProtKB=W5N830 W5N830 PTHR24055:SF335 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015652.1|UniProtKB=W5NF57 W5NF57 PTHR10159:SF109 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;endoderm formation#GO:0001706;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;regulation of cellular process#GO:0050794;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;embryonic morphogenesis#GO:0048598 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000004080.1|UniProtKB=W5M952 W5M952 PTHR24092:SF98 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IB ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;nervous system development#GO:0007399;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;biological regulation#GO:0065007;lipid translocation#GO:0034204;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron development#GO:0048666;lipid localization#GO:0010876;generation of neurons#GO:0048699;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008085.1|UniProtKB=W5MN60 W5MN60 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007421.1|UniProtKB=W5MKZ4 W5MKZ4 PTHR10629:SF52 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000010288.1|UniProtKB=W5MW45 W5MW45 HTRA3 PTHR22939:SF14 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA3 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018104.1|UniProtKB=W5NNJ6 W5NNJ6 PTHR24070:SF290 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE, FAMILY 10, MEMBER A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013821.1|UniProtKB=W5N8T8 W5N8T8 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012184.1|UniProtKB=W5N2Y6 W5N2Y6 PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000013537.1|UniProtKB=W5N7T7 W5N7T7 PTHR46227:SF4 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2 protein localization to plasma membrane#GO:0072659;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein-containing complex localization#GO:0031503 LEPOC|Ensembl=ENSLOCG00000010176.1|UniProtKB=W5MVP9 W5MVP9 PTHR43903:SF10 NEUROLIGIN NEUROLIGIN-4, Y-LINKED synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013778.1|UniProtKB=W5N8N2 W5N8N2 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 LEPOC|Ensembl=ENSLOCG00000001739.1|UniProtKB=W5M0V5 W5M0V5 PTHR10231:SF90 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A5-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003676.1|UniProtKB=W5M7N0 W5M7N0 PTHR45713:SF8 FTP DOMAIN-CONTAINING PROTEIN SI:CH211-215K15.4 LEPOC|Ensembl=ENSLOCG00000008000.1|UniProtKB=W5MMV9 W5MMV9 PTHR24023:SF1059 COLLAGEN ALPHA COLLAGEN, TYPE XI, ALPHA 1A structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000015573.1|UniProtKB=W5NEW2 W5NEW2 ATP6V1FNB PTHR35826:SF2 PROTEIN ATP6V1FNB-LIKE PROTEIN ATP6V1FNB LEPOC|Ensembl=ENSLOCG00000009254.1|UniProtKB=W5MSE0 W5MSE0 PTHR11792:SF15 ARRESTIN S-ARRESTIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;receptor internalization#GO:0031623;transport#GO:0006810;endocytosis#GO:0006897;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 9+0 non-motile cilium#GO:0097731;cytoplasm#GO:0005737;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;photoreceptor inner segment#GO:0001917;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>beta-arrestin#P01456;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>beta-arrestin#P00757 LEPOC|Ensembl=ENSLOCG00000013656.1|UniProtKB=W5N879 W5N879 PTHR47634:SF24 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 3-LIKE ISOFORM X1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;protein-containing complex assembly#GO:0065003;RNA processing#GO:0006396;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;regulation of mRNA processing#GO:0050684;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;peptidyl-serine modification#GO:0018209;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008065.1|UniProtKB=W5MN34 W5MN34 PTHR11210:SF60 RING BOX RING-BOX PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;cullin family protein binding#GO:0097602;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012759.1|UniProtKB=W5N4Y9 W5N4Y9 PTHR24394:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 42 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015175.1|UniProtKB=W5NDG5 W5NDG5 PTHR19443:SF3 HEXOKINASE HEXOKINASE-4 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of secretion#GO:0051046;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;regulation of protein localization#GO:0032880;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;regulation of peptide hormone secretion#GO:0090276;oxoacid metabolic process#GO:0043436;regulation of protein secretion#GO:0050708;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;regulation of cellular localization#GO:0060341;intracellular chemical homeostasis#GO:0055082;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;organophosphate catabolic process#GO:0046434;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;regulation of signaling#GO:0023051;regulation of insulin secretion#GO:0050796;organonitrogen compound catabolic process#GO:1901565;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;regulation of hormone secretion#GO:0046883;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;regulation of protein transport#GO:0051223;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;carbohydrate phosphorylation#GO:0046835;organonitrogen compound metabolic process#GO:1901564;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;glucose metabolic process#GO:0006006;intracellular glucose homeostasis#GO:0001678;aromatic compound catabolic process#GO:0019439;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000004071.1|UniProtKB=W5M8Z9 W5M8Z9 PTHR46403:SF1 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758 LEPOC|Ensembl=ENSLOCG00000008494.1|UniProtKB=W5MPM8 W5MPM8 MARCHF3 PTHR46065:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005818.1|UniProtKB=W5MF73 W5MF73 TBC1D13 PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;transport#GO:0006810;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000017529.1|UniProtKB=W5NLX5 W5NLX5 PTHR11863:SF106 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE-LIKE PROTEIN 2 steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;steroid biosynthetic process#GO:0006694;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017188.1|UniProtKB=W5NKT4 W5NKT4 PTHR43157:SF72 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 14 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013014.1|UniProtKB=W5N5X6 W5N5X6 PTHR14647:SF57 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004743.1|UniProtKB=W5MBD4 W5MBD4 PTHR42693:SF47 ARYLSULFATASE FAMILY MEMBER N-ACETYLGALACTOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005114.1|UniProtKB=W5MCQ1 W5MCQ1 PTHR24072:SF141 RHO FAMILY GTPASE BTB DOMAIN-CONTAINING PROTEIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004123.1|UniProtKB=W5M976 W5M976 PTHR43270:SF11 BETA-ALA-HIS DIPEPTIDASE CYTOSOLIC NON-SPECIFIC DIPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010201.1|UniProtKB=W5MVT8 W5MVT8 ELAPOR1 PTHR22727:SF13 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;macroautophagy#GO:0016236;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;late endosome#GO:0005770;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000139.1|UniProtKB=W5LVJ5 W5LVJ5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013081.1|UniProtKB=W5N654 W5N654 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016711.1|UniProtKB=W5NJ40 W5NJ40 PTHR43329:SF4 EPOXIDE HYDROLASE BIFUNCTIONAL EPOXIDE HYDROLASE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004133.1|UniProtKB=W5M979 W5M979 PTHR33962:SF1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 RMI2 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;regulation of double-strand break repair#GO:2000779;negative regulation of biological process#GO:0048519;regulation of chromosome segregation#GO:0051983;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;negative regulation of DNA repair#GO:0045738;regulation of cellular component organization#GO:0051128;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of sister chromatid segregation#GO:0033045;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000008931.1|UniProtKB=W5MR67 W5MR67 PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 LEPOC|Ensembl=ENSLOCG00000012755.1|UniProtKB=W5N4Y7 W5N4Y7 PTHR21561:SF12 INO80 COMPLEX SUBUNIT B INO80 COMPLEX SUBUNIT B membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;cellular anatomical entity#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000015615.1|UniProtKB=W5NF15 W5NF15 PTHR22776:SF88 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MAL-LIKE PROTEIN-RELATED structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005712.1|UniProtKB=W5MET8 W5MET8 MORN1 PTHR23084:SF263 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED MORN REPEAT-CONTAINING PROTEIN 1 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013442.1|UniProtKB=W5N7I0 W5N7I0 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000000375.1|UniProtKB=W5LWA1 W5LWA1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004965.1|UniProtKB=W5MC59 W5MC59 PTHR21340:SF0 DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015863.1|UniProtKB=W5NFX1 W5NFX1 PTHR13037:SF23 FORMIN ACTIN NUCLEATION-PROMOTING FACTOR WASL Huntington disease#P00029>N-Wasp#P00769;Cytoskeletal regulation by Rho GTPase#P00016>N-WASP#P00525 LEPOC|Ensembl=ENSLOCG00000003409.1|UniProtKB=W5M6Q5 W5M6Q5 PTHR23220:SF79 INTEGRIN ALPHA INTEGRIN ALPHA-E cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000016841.1|UniProtKB=W5NJK8 W5NJK8 PTHR19282:SF41 TETRASPANIN TETRASPANIN-9 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008842.1|UniProtKB=W5MQV2 W5MQV2 PTHR11211:SF15 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016144.1|UniProtKB=W5NGY3 W5NGY3 PTHR10689:SF6 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012449.1|UniProtKB=W5N3W6 W5N3W6 PTHR10824:SF17 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 6 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000007279.1|UniProtKB=W5MKA3 W5MKA3 PTHR46882:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 positive regulation of nitrogen compound metabolic process#GO:0051173;response to hypoxia#GO:0001666;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;response to oxygen levels#GO:0070482;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;positive regulation of mRNA metabolic process#GO:1903313;regulation of apoptotic process#GO:0042981;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of mRNA catabolic process#GO:0061014;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000000609.1|UniProtKB=W5LX24 W5LX24 PTHR14928:SF13 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011300.1|UniProtKB=W5MZS9 W5MZS9 PTHR11346:SF97 GALECTIN GALECTIN-1 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;carbohydrate binding#GO:0030246;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010729.1|UniProtKB=W5MXN7 W5MXN7 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016856.1|UniProtKB=W5NJM8 W5NJM8 SCAF8 PTHR23140:SF1 RNA PROCESSING PROTEIN LD23810P SR-RELATED CTD ASSOCIATED FACTOR 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000017599.1|UniProtKB=W5NM45 W5NM45 PTHR11214:SF91 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 9 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006416.1|UniProtKB=W5MH93 W5MH93 PTHR21377:SF0 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210B, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012901.1|UniProtKB=W5N5H4 W5N5H4 PTHR23235:SF48 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016743.1|UniProtKB=W5NJ87 W5NJ87 CUL9 PTHR22771:SF4 CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING CULLIN 7-RELATED LEPOC|Ensembl=ENSLOCG00000011557.1|UniProtKB=W5N0P3 W5N0P3 PTHR11660:SF50 SOLUTE CARRIER FAMILY 40 MEMBER SOLUTE CARRIER FAMILY 40 MEMBER secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008545.1|UniProtKB=W5MPU1 W5MPU1 PTHR10211:SF0 DEOXYRIBODIPYRIMIDINE PHOTOLYASE DEOXYRIBODIPYRIMIDINE PHOTO-LYASE catalytic activity, acting on a nucleic acid#GO:0140640;lyase activity#GO:0016829;catalytic activity, acting on DNA#GO:0140097;deoxyribodipyrimidine photo-lyase activity#GO:0003904;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;photoreactive repair#GO:0000719;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000007532.1|UniProtKB=W5ML83 W5ML83 PTHR45807:SF6 TYROSINE-PROTEIN KINASE HOPSCOTCH NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;kinase activity#GO:0016301;cytokine receptor binding#GO:0005126;protein kinase activity#GO:0004672 signal transduction#GO:0007165;response to cytokine#GO:0034097;response to peptide hormone#GO:0043434;developmental process#GO:0032502;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor tyrosine protein kinase#PC00168 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846 LEPOC|Ensembl=ENSLOCG00000003752.1|UniProtKB=W5M7W0 W5M7W0 PTHR23414:SF3 ADRENOMEDULLIN, ADM PRO-ADRENOMEDULLIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 blood circulation#GO:0008015;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000016805.1|UniProtKB=W5NJG2 W5NJG2 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000002051.1|UniProtKB=W5M1X3 W5M1X3 PTHR21035:SF2 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS26 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014586.1|UniProtKB=W5NBD9 W5NBD9 PTHR21461:SF52 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000592.1|UniProtKB=W5LX15 W5LX15 PTHR24416:SF631 TYROSINE-PROTEIN KINASE RECEPTOR SERINE_THREONINE_TYROSINE KINASE 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005438.1|UniProtKB=W5MDW0 W5MDW0 PTHR23119:SF6 DISCS LARGE DISKS LARGE HOMOLOG 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;developmental process#GO:0032502;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;signaling#GO:0023052;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;neuron projection#GO:0043005;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;basal part of cell#GO:0045178;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007397.1|UniProtKB=W5MKS2 W5MKS2 PTHR16127:SF14 TAXILIN GAMMA-TAXILIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006537.1|UniProtKB=W5MHN9 W5MHN9 PTHR19969:SF5 SH2-SH3 ADAPTOR PROTEIN-RELATED CRK-LIKE PROTEIN molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Crk#P00933;Angiogenesis#P00005>Crk#P00207 LEPOC|Ensembl=ENSLOCG00000000493.1|UniProtKB=W5LWP0 W5LWP0 PHRF1 PTHR12618:SF20 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000018044.1|UniProtKB=W5NND6 W5NND6 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005928.1|UniProtKB=W5MFK0 W5MFK0 PTHR24031:SF594 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX52-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;90S preribosome#GO:0030686 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010272.1|UniProtKB=W5MW22 W5MW22 PTHR13832:SF849 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1H hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011912.1|UniProtKB=W5N1Y6 W5N1Y6 PTHR13318:SF50 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 7 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000009151.1|UniProtKB=W5MRZ9 W5MRZ9 PTHR12845:SF8 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN-1 positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013965.1|UniProtKB=W5N9B6 W5N9B6 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017025.1|UniProtKB=W5NK83 W5NK83 PTHR12027:SF73 WNT RELATED PROTEIN WNT-7B molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of JNK cascade#GO:0046330;regulation of JNK cascade#GO:0046328;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000006371.1|UniProtKB=W5MH31 W5MH31 PTHR11265:SF0 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016648.1|UniProtKB=W5NIV6 W5NIV6 PTHR12197:SF288 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000002338.1|UniProtKB=W5M2X3 W5M2X3 PTHR25465:SF32 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018069.1|UniProtKB=W5NNG1 W5NNG1 PTHR11537:SF23 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;axon terminus#GO:0043679;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;transmembrane transporter complex#GO:1902495;main axon#GO:0044304;distal axon#GO:0150034;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000012215.1|UniProtKB=W5N317 W5N317 PTHR47980:SF16 LD44762P RAS-RELATED PROTEIN RAB-40B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012407.1|UniProtKB=W5N3S6 W5N3S6 PTHR11635:SF129 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT protein kinase A binding#GO:0051018;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 LEPOC|Ensembl=ENSLOCG00000011827.1|UniProtKB=W5N1N2 W5N1N2 PTHR47227:SF5 DNA-DIRECTED RNA POLYMERASE SUBUNIT K DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 LEPOC|Ensembl=ENSLOCG00000010394.1|UniProtKB=W5MWI7 W5MWI7 PTHR12166:SF6 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 1 positive regulation of secretion#GO:0051047;transport#GO:0006810;regulation of localization#GO:0032879;positive regulation of transport#GO:0051050;vesicle-mediated transport#GO:0016192;regulation of secretion by cell#GO:1903530;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157;export from cell#GO:0140352;secretion by cell#GO:0032940 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001510.1|UniProtKB=W5M019 W5M019 SH2B2 PTHR10872:SF4 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 2 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004364.1|UniProtKB=W5MA20 W5MA20 SZT2 PTHR14918:SF3 KICSTOR COMPLEX PROTEIN SZT2 KICSTOR COMPLEX PROTEIN SZT2 LEPOC|Ensembl=ENSLOCG00000002073.1|UniProtKB=W5M227 W5M227 PTHR23116:SF36 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED HARMONIN stereocilium#GO:0032420;stereocilium bundle#GO:0032421;protein-containing complex#GO:0032991;cluster of actin-based cell projections#GO:0098862;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003442.1|UniProtKB=W5M6R9 W5M6R9 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002988.1|UniProtKB=W5M561 W5M561 HSF5 PTHR10015:SF278 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 5 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015667.1|UniProtKB=W5NF75 W5NF75 PTHR24241:SF143 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RFAMIDE PEPTIDE RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009949.1|UniProtKB=W5MUV9 W5MUV9 PTHR12629:SF5 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013165.1|UniProtKB=W5N6F7 W5N6F7 PTHR22791:SF14 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 227 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010839.1|UniProtKB=W5MY26 W5MY26 PTHR23282:SF148 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015704.1|UniProtKB=W5NFC2 W5NFC2 PTHR22799:SF1 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 11 MEMBER A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 multicellular organismal process#GO:0032501;ossification#GO:0001503 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000970.1|UniProtKB=W5LYA0 W5LYA0 PTHR45615:SF1 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;actin filament-based movement#GO:0030048;animal organ development#GO:0048513;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle contraction#GO:0060048;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;heart process#GO:0003015;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000008538.1|UniProtKB=W5MPS7 W5MPS7 PTHR24291:SF201 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003773.1|UniProtKB=W5M815 W5M815 PTHR15138:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 4 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000016461.1|UniProtKB=W5NI76 W5NI76 PTHR11537:SF91 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014377.1|UniProtKB=W5NAP1 W5NAP1 PTHR14344:SF3 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001933.1|UniProtKB=W5M1H6 W5M1H6 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000006100.1|UniProtKB=W5MG61 W5MG61 PTHR10201:SF25 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-15 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000017481.1|UniProtKB=W5NLS7 W5NLS7 PTHR11984:SF49 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000013526.1|UniProtKB=W5N7R9 W5N7R9 PTHR12348:SF24 TSC22 TSC22 DOMAIN FAMILY PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000007921.1|UniProtKB=W5MML5 W5MML5 KATNIP PTHR21534:SF0 KATANIN-INTERACTING PROTEIN KATANIN-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000000035.1|UniProtKB=W5LV87 W5LV87 PTHR24126:SF7 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005780.1|UniProtKB=W5MF37 W5MF37 PTHR13222:SF1 RB1-INDUCIBLE COILED-COIL RB1-INDUCIBLE COILED-COIL PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macroautophagy#GO:0016236;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;autophagy of mitochondrion#GO:0000422;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;cellular component assembly#GO:0022607;positive regulation of phosphorylation#GO:0042327;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organelle disassembly#GO:1903008;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;reticulophagy#GO:0061709;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016236.1|UniProtKB=W5NHB0 W5NHB0 PTHR11843:SF0 40S RIBOSOMAL PROTEIN S12 SMALL RIBOSOMAL SUBUNIT PROTEIN ES12 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;ribosomal small subunit biogenesis#GO:0042274;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007266.1|UniProtKB=W5MK77 W5MK77 PTHR16476:SF4 FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A PROTEIN FAM216A LEPOC|Ensembl=ENSLOCG00000014553.1|UniProtKB=W5NBA1 W5NBA1 PTHR48092:SF21 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007977.1|UniProtKB=W5MMT4 W5MMT4 PTHR11036:SF85 SEMAPHORIN SI:CH211-113G11.6 ISOFORM X1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007585.1|UniProtKB=W5MLE1 W5MLE1 C1orf53 PTHR21037:SF2 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL SIMILAR TO NOVEL PROTEIN ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015235.1|UniProtKB=W5NDN9 W5NDN9 PTHR10024:SF46 SYNAPTOTAGMIN SYNAPTOTAGMIN-10 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016582.1|UniProtKB=W5NIM4 W5NIM4 QRSL1 PTHR11895:SF7 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000005641.1|UniProtKB=W5MEJ9 W5MEJ9 PTHR24240:SF90 OPSIN RPE-RETINAL G PROTEIN-COUPLED RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003903.1|UniProtKB=W5M8E8 W5M8E8 WDR4 PTHR16288:SF0 WD40 REPEAT PROTEIN 4 TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017198.1|UniProtKB=W5NKV2 W5NKV2 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248 oxidase#PC00175;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000001012.1|UniProtKB=W5LYD1 W5LYD1 PTHR24413:SF91 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN-LIKE enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;regulation of protein metabolic process#GO:0051246;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014090.1|UniProtKB=W5N9Q1 W5N9Q1 PTHR34765:SF1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015843.1|UniProtKB=W5NFU4 W5NFU4 PTHR11062:SF97 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 acetylglucosaminyltransferase activity#GO:0008375;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006018.1|UniProtKB=W5MFV9 W5MFV9 GALNT15 PTHR11675:SF36 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 15 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016736.1|UniProtKB=W5NJ71 W5NJ71 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006012.1|UniProtKB=W5MFV6 W5MFV6 PTHR24068:SF177 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein K63-linked ubiquitination#GO:0070534;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000016530.1|UniProtKB=W5NIG3 W5NIG3 LHCGR PTHR24372:SF1 GLYCOPROTEIN HORMONE RECEPTOR LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of adenylate cyclase activity#GO:0045762;reproductive system development#GO:0061458;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;rhythmic process#GO:0048511;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;hormone-mediated signaling pathway#GO:0009755;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;reproductive process#GO:0022414;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;male sex differentiation#GO:0046661;response to organic substance#GO:0010033;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular response to organic substance#GO:0071310;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;developmental process involved in reproduction#GO:0003006;response to stimulus#GO:0050896;response to hormone#GO:0009725;reproduction#GO:0000003;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of lyase activity#GO:0051349 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008263.1|UniProtKB=W5MNT8 W5MNT8 PTHR10226:SF7 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN SPHKAP protein kinase A binding#GO:0051018;protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001427.1|UniProtKB=W5LZX3 W5LZX3 PTHR23119:SF5 DISCS LARGE DISKS LARGE HOMOLOG 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;developmental process#GO:0032502;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;signaling#GO:0023052;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;neuron projection#GO:0043005;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;basal part of cell#GO:0045178;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013336.1|UniProtKB=W5N729 W5N729 PTHR11675:SF3 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 16 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012828.1|UniProtKB=W5N575 W5N575 PTHR47133:SF1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779 LEPOC|Ensembl=ENSLOCG00000001675.1|UniProtKB=W5M0R5 W5M0R5 PTHR24543:SF302 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR V oxidoreductase#PC00176 Blood coagulation#P00011>FVa#P00435;Blood coagulation#P00011>FV#P00432 LEPOC|Ensembl=ENSLOCG00000001529.1|UniProtKB=W5M057 W5M057 SENP5 PTHR12606:SF10 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 5 hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007350.1|UniProtKB=W5MKJ7 W5MKJ7 PTHR10845:SF43 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 2 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CCKR signaling map#P06959>RGS2#P07040;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000005982.1|UniProtKB=W5MFS2 W5MFS2 PTHR14882:SF4 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING PROTEIN 92 LEPOC|Ensembl=ENSLOCG00000000956.1|UniProtKB=W5LY71 W5LY71 PTHR24221:SF654 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017893.1|UniProtKB=W5NMY7 W5NMY7 PTHR11849:SF276 ETS TRANSCRIPTION FACTOR SPI-C-LIKE transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000007351.1|UniProtKB=W5MKJ8 W5MKJ8 DEUP1 PTHR18875:SF3 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO CENTROSOMAL PROTEIN OF 63 KDA cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;centriole assembly#GO:0098534;epithelium development#GO:0060429;developmental process#GO:0032502;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;tissue development#GO:0009888;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012111.1|UniProtKB=W5N2P6 W5N2P6 SPDL1 PTHR32123:SF9 BICD FAMILY-LIKE CARGO ADAPTER PROTEIN SPINDLY membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002529.1|UniProtKB=W5M3L9 W5M3L9 PTHR13663:SF2 SIMILAR TO RIKEN CDNA 6430548M08 SIMILAR TO RIKEN CDNA 6430548M08 LEPOC|Ensembl=ENSLOCG00000010747.1|UniProtKB=W5MXQ7 W5MXQ7 PTHR23240:SF26 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED 5' EXONUCLEASE APOLLO hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016604.1|UniProtKB=W5NIP9 W5NIP9 PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017297.1|UniProtKB=W5NL93 W5NL93 PTHR18860:SF16 14-3-3 PROTEIN 14-3-3 PROTEIN ETA localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 LEPOC|Ensembl=ENSLOCG00000015943.1|UniProtKB=W5NG72 W5NG72 PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 LEPOC|Ensembl=ENSLOCG00000005865.1|UniProtKB=W5MFC7 W5MFC7 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013484.1|UniProtKB=W5N7L6 W5N7L6 PTHR10031:SF32 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE LIPID-BINDING PROTEIN cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010230.1|UniProtKB=W5MVW9 W5MVW9 PTHR45619:SF12 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway#P00059>PP2A#P04630;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway feedback loops 2#P04398>PP2A-C#P04659;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000007132.1|UniProtKB=W5MJS4 W5MJS4 COQ7 PTHR11237:SF4 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000008154.1|UniProtKB=W5MNE0 W5MNE0 PTHR16551:SF4 AGOUTI RELATED AGOUTI-RELATED PROTEIN neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;behavior#GO:0007610;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012760.1|UniProtKB=W5N4Z4 W5N4Z4 PTHR24056:SF126 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;protein modification process#GO:0036211;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005489.1|UniProtKB=W5ME12 W5ME12 PTHR13394:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000012706.1|UniProtKB=W5N4S2 W5N4S2 PTHR11844:SF24 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 2 peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000007512.1|UniProtKB=W5ML54 W5ML54 PTHR22923:SF5 CEREBELLIN-RELATED CEREBELLIN-1 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006046.1|UniProtKB=W5MG32 W5MG32 PTHR11139:SF68 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015935.1|UniProtKB=W5NG59 W5NG59 PTHR12307:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3A phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000008022.1|UniProtKB=W5MMY7 W5MMY7 RIMOC1 PTHR28494:SF1 UPF0600 PROTEIN C5ORF51 RAB7A-INTERACTING MON1-CCZ1 COMPLEX SUBUNIT 1 LEPOC|Ensembl=ENSLOCG00000005068.1|UniProtKB=W5MCJ9 W5MCJ9 PTHR23339:SF122 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PALADIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015658.1|UniProtKB=W5NF64 W5NF64 PTHR16483:SF1 GASTROKINE 1 GASTROKINE-1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000017721.1|UniProtKB=W5NMG6 W5NMG6 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005197.1|UniProtKB=W5MD14 W5MD14 PTHR12587:SF15 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-1 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002953.1|UniProtKB=W5M538 W5M538 PTHR10837:SF8 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003873.1|UniProtKB=W5M8C4 W5M8C4 PTHR16059:SF16 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015033.1|UniProtKB=W5NCZ6 W5NCZ6 PTHR46003:SF2 HOST CELL FACTOR HOST CELL FACTOR 2 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000006446.1|UniProtKB=W5MHD2 W5MHD2 PTHR20938:SF0 INTEGRATOR COMPLEX SUBUNIT 4 INTEGRATOR COMPLEX SUBUNIT 4 LEPOC|Ensembl=ENSLOCG00000011929.1|UniProtKB=W5N207 W5N207 PTHR12964:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 response to stimulus#GO:0050896;response to stress#GO:0006950;response to oxidative stress#GO:0006979 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008008.1|UniProtKB=W5MMW9 W5MMW9 PTHR12548:SF5 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013989.1|UniProtKB=W5N9D1 W5N9D1 PTHR12002:SF74 CLAUDIN CLAUDIN-15 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000017888.1|UniProtKB=W5NMY2 W5NMY2 PTHR24249:SF220 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 4 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008244.1|UniProtKB=W5MNP5 W5MNP5 PTHR10582:SF25 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018116.1|UniProtKB=W5NNK8 W5NNK8 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016354.1|UniProtKB=W5NHT5 W5NHT5 PTHR28489:SF1 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3 LEPOC|Ensembl=ENSLOCG00000001870.1|UniProtKB=W5M1D3 W5M1D3 PTHR11409:SF43 ADENOSINE DEAMINASE ADENOSINE DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;purine nucleoside catabolic process#GO:0006152;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;adenosine metabolic process#GO:0046085;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 LEPOC|Ensembl=ENSLOCG00000006419.1|UniProtKB=W5MH97 W5MH97 PTHR11256:SF48 BCL-2 RELATED BCL-2-RELATED OVARIAN KILLER PROTEIN protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bok#P00261 LEPOC|Ensembl=ENSLOCG00000005546.1|UniProtKB=W5ME87 W5ME87 PTHR46512:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP8 negative regulation of biological process#GO:0048519;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 envelope#GO:0031975;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004728.1|UniProtKB=W5MBA6 W5MBA6 PTHR12403:SF11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013042.1|UniProtKB=W5N625 W5N625 PTHR13800:SF8 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 7 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;monoatomic ion transport#GO:0006811;chemical homeostasis#GO:0048878;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003108.1|UniProtKB=W5M5L0 W5M5L0 PTHR24031:SF301 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010112.1|UniProtKB=W5MVF8 W5MVF8 CD274 PTHR25466:SF3 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 1 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009899.1|UniProtKB=W5MUP3 W5MUP3 PTHR13817:SF181 TITIN IMMUNOGLOBULIN-LIKE AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015673.1|UniProtKB=W5NF84 W5NF84 NEFM PTHR23214:SF1 NEUROFILAMENT TRIPLET H PROTEIN NEUROFILAMENT HEAVY POLYPEPTIDE LEPOC|Ensembl=ENSLOCG00000000866.1|UniProtKB=W5LXV8 W5LXV8 PTHR12752:SF7 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 LEPOC|Ensembl=ENSLOCG00000008596.1|UniProtKB=W5MPZ8 W5MPZ8 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14 ubiquitin-like protein peptidase activity#GO:0019783;proteasome binding#GO:0070628;metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein-containing complex binding#GO:0044877;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 translation initiation factor#PC00224;translation factor#PC00223 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000000485.1|UniProtKB=W5LWN3 W5LWN3 PTHR23036:SF16 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014173.1|UniProtKB=W5N9Z7 W5N9Z7 PTHR11346:SF86 GALECTIN GALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014563.1|UniProtKB=W5NBB6 W5NBB6 PTHR24060:SF24 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000010861.1|UniProtKB=W5MY49 W5MY49 PTHR32235:SF1 NON-HOMOLOGOUS END-JOINING FACTOR 1 NON-HOMOLOGOUS END-JOINING FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013745.1|UniProtKB=W5N8J2 W5N8J2 PTHR43461:SF1 TRANSMEMBRANE PROTEIN 256 TRANSMEMBRANE PROTEIN 256 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016765.1|UniProtKB=W5NJB4 W5NJB4 PTHR10807:SF56 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 9 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009465.1|UniProtKB=W5MT47 W5MT47 DCSTAMP PTHR21041:SF2 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN LEPOC|Ensembl=ENSLOCG00000016568.1|UniProtKB=W5NIK6 W5NIK6 PTHR16262:SF2 PEROXISOME ASSEMBLY PROTEIN 26 PEROXISOME ASSEMBLY PROTEIN 26 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016592.1|UniProtKB=W5NIN5 W5NIN5 PTHR13037:SF16 FORMIN FORMIN-2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000015581.1|UniProtKB=W5NEX3 W5NEX3 PTHR31283:SF5 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT LAGE3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;tRNA threonylcarbamoyladenosine metabolic process#GO:0070525;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000010830.1|UniProtKB=W5MY15 W5MY15 PTHR11153:SF8 SIDEROFLEXIN SIDEROFLEXIN-1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012891.1|UniProtKB=W5N5H3 W5N5H3 PTHR48099:SF1 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016491.1|UniProtKB=W5NIB1 W5NIB1 PTHR10159:SF343 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 16 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000014895.1|UniProtKB=W5NCI2 W5NCI2 PTHR14564:SF3 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC27 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000016522.1|UniProtKB=W5NIE9 W5NIE9 PTHR15537:SF2 F-BOX ONLY PROTEIN 7 F-BOX ONLY PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000009447.1|UniProtKB=W5MT26 W5MT26 PTHR11647:SF50 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 LEPOC|Ensembl=ENSLOCG00000003338.1|UniProtKB=W5M6D4 W5M6D4 PTHR16070:SF1 PROTEIN FAM222A-RELATED PROTEIN FAM222B LEPOC|Ensembl=ENSLOCG00000010694.1|UniProtKB=W5MXI9 W5MXI9 PTHR11890:SF3 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013654.1|UniProtKB=W5N876 W5N876 PTHR24231:SF52 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000238.1|UniProtKB=W5LVV5 W5LVV5 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014413.1|UniProtKB=W5NAT3 W5NAT3 PTHR12400:SF47 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000781.1|UniProtKB=W5LXK8 W5LXK8 PTHR11599:SF53 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-8 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006983.1|UniProtKB=W5MJ93 W5MJ93 PTHR45829:SF5 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 33 nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial genome maintenance#GO:0000002;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;nucleobase-containing compound transport#GO:0015931;mitochondrion organization#GO:0007005;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004973.1|UniProtKB=W5MC77 W5MC77 PTHR19212:SF5 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008732.1|UniProtKB=W5MQH7 W5MQH7 PTHR43806:SF60 PEPTIDASE S8 PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 9 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010364.1|UniProtKB=W5MWE9 W5MWE9 PTHR23023:SF210 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010956.1|UniProtKB=W5MYI6 W5MYI6 PTHR22847:SF637 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B LEPOC|Ensembl=ENSLOCG00000004082.1|UniProtKB=W5M949 W5M949 PTHR19432:SF6 SUGAR TRANSPORTER PROTON-ASSOCIATED SUGAR TRANSPORTER A solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;carbohydrate transmembrane transporter activity#GO:0015144;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009882.1|UniProtKB=W5MUQ9 W5MUQ9 PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;post-translational protein modification#GO:0043687;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 LEPOC|Ensembl=ENSLOCG00000002056.1|UniProtKB=W5M1X6 W5M1X6 PTHR21469:SF4 EXOPHILIN-5 EXOPHILIN-5 LEPOC|Ensembl=ENSLOCG00000005768.1|UniProtKB=W5MF21 W5MF21 PTHR10226:SF3 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 11 protein kinase A binding#GO:0051018;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016981.1|UniProtKB=W5NK34 W5NK34 PTHR11588:SF13 TUBULIN TUBULIN EPSILON CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002903.1|UniProtKB=W5M4V2 W5M4V2 PTHR13460:SF0 FAMILY NOT NAMED MALECTIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003113.1|UniProtKB=W5M5K4 W5M5K4 PTHR45869:SF2 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000006712.1|UniProtKB=W5MI96 W5MI96 PTHR23067:SF12 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385D membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003643.1|UniProtKB=W5M7H3 W5M7H3 PTHR14949:SF56 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EGF-LIKE-DOMAIN, MULTIPLE 7 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015801.1|UniProtKB=W5NFP4 W5NFP4 PTHR12106:SF46 SORTILIN RELATED SORTILIN ISOFORM X1 Golgi to endosome transport#GO:0006895;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016771.1|UniProtKB=W5NJC0 W5NJC0 PTHR24023:SF1047 COLLAGEN ALPHA SCAVENGER RECEPTOR CLASS A MEMBER 3 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000015370.1|UniProtKB=W5NE56 W5NE56 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000013399.1|UniProtKB=W5N7A6 W5N7A6 PTHR21559:SF22 DYSTROGLYCAN-RELATED DYSTROGLYCAN 1 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;muscle organ development#GO:0007517;neurogenesis#GO:0022008;cell projection organization#GO:0030030;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 membrane protein complex#GO:0098796;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604;plasma membrane protein complex#GO:0098797;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009170.1|UniProtKB=W5MS37 W5MS37 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 LEPOC|Ensembl=ENSLOCG00000015006.1|UniProtKB=W5NCW9 W5NCW9 PTHR12103:SF11 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012448.1|UniProtKB=W5N3W3 W5N3W3 PTHR13820:SF10 SYNUCLEIN GAMMA-SYNUCLEIN cation binding#GO:0043169;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cell-cell signaling#GO:0007267;signaling#GO:0023052;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;cell body#GO:0044297;distal axon#GO:0150034;cell projection#GO:0042995 membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>gamma-Synuclein#P01231 LEPOC|Ensembl=ENSLOCG00000009679.1|UniProtKB=W5MTW4 W5MTW4 GPA33 PTHR44969:SF1 CELL SURFACE A33 ANTIGEN CELL SURFACE A33 ANTIGEN LEPOC|Ensembl=ENSLOCG00000007179.1|UniProtKB=W5MJX7 W5MJX7 PTHR46294:SF1 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000005.1|UniProtKB=W5LV48 W5LV48 PTHR23326:SF1 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000010610.1|UniProtKB=W5MX90 W5MX90 PTHR10528:SF15 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 4 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010331.1|UniProtKB=W5MW98 W5MW98 PTHR11949:SF3 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000017775.1|UniProtKB=W5NMM0 W5NMM0 PTHR24232:SF1 G-PROTEIN COUPLED RECEPTOR N-ARACHIDONYL GLYCINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000814.1|UniProtKB=W5LXP6 W5LXP6 PTHR23351:SF23 FOS TRANSCRIPTION FACTOR-RELATED CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06902;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#P06821;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06689 LEPOC|Ensembl=ENSLOCG00000008290.1|UniProtKB=W5MNW2 W5MNW2 PTHR12069:SF0 DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000016678.1|UniProtKB=W5NIZ7 W5NIZ7 PTHR14343:SF4 VWFA DOMAIN-CONTAINING PROTEIN DUF4537 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011741.1|UniProtKB=W5N1C9 W5N1C9 ATG14 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;organelle localization#GO:0051640;macroautophagy#GO:0016236;mitophagy#GO:0000423;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;intracellular organelle#GO:0043229;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013211.1|UniProtKB=W5N6L8 W5N6L8 PTHR45620:SF16 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE RELEASING HORMONE RECEPTOR 2 PRECURSOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005082.1|UniProtKB=W5MCL0 W5MCL0 PTHR14879:SF3 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF34 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;protein catabolic process#GO:0030163;regulation of apoptotic signaling pathway#GO:2001233;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;proteasomal protein catabolic process#GO:0010498;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;negative regulation of signaling#GO:0023057;negative regulation of endopeptidase activity#GO:0010951;regulation of extrinsic apoptotic signaling pathway#GO:2001236;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;post-translational protein modification#GO:0043687;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015641.1|UniProtKB=W5NF45 W5NF45 PTHR12067:SF5 PODOCALYXIN PODOCALYXIN negative regulation of biological process#GO:0048519;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;negative regulation of cell adhesion#GO:0007162;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785;regulation of cell adhesion#GO:0030155;cell migration#GO:0016477;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of cell-cell adhesion#GO:0022409;regulation of cell adhesion mediated by integrin#GO:0033628 microvillus#GO:0005902;plasma membrane region#GO:0098590;actin-based cell projection#GO:0098858;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008619.1|UniProtKB=W5MQ20 W5MQ20 PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 LEPOC|Ensembl=ENSLOCG00000017403.1|UniProtKB=W5NLJ9 W5NLJ9 PTHR35073:SF1 OTOSPIRALIN OTOSPIRALIN multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;sensory perception of sound#GO:0007605;system process#GO:0003008 LEPOC|Ensembl=ENSLOCG00000017585.1|UniProtKB=W5NM31 W5NM31 PTHR46675:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF182 E3 UBIQUITIN-PROTEIN LIGASE RNF182 LEPOC|Ensembl=ENSLOCG00000005658.1|UniProtKB=W5MEM1 W5MEM1 PTHR23235:SF141 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002715.1|UniProtKB=W5M4B2 W5M4B2 PTHR45807:SF3 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK3 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;kinase activity#GO:0016301;cytokine receptor binding#GO:0005126;protein kinase activity#GO:0004672 signal transduction#GO:0007165;response to cytokine#GO:0034097;response to peptide hormone#GO:0043434;developmental process#GO:0032502;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor tyrosine protein kinase#PC00168 PDGF signaling pathway#P00047>Jak#P01155;Interleukin signaling pathway#P00036>Jak#P00978;JAK/STAT signaling pathway#P00038>Jak#P01034 LEPOC|Ensembl=ENSLOCG00000009241.1|UniProtKB=W5MSC2 W5MSC2 PTHR23316:SF6 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-4 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007781.1|UniProtKB=W5MM52 W5MM52 PTHR45954:SF3 LD33695P G-PROTEIN-SIGNALING MODULATOR 2 nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;binding#GO:0005488;molecular function regulator activity#GO:0098772 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 LEPOC|Ensembl=ENSLOCG00000000345.1|UniProtKB=W5LW70 W5LW70 PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 TCA cycle#P00051>Succinate Dehydrogenase#P01273 LEPOC|Ensembl=ENSLOCG00000017586.1|UniProtKB=W5NM32 W5NM32 PTHR23334:SF5 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000005454.1|UniProtKB=W5MDX4 W5MDX4 SLC25A30 PTHR45618:SF11 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED KIDNEY MITOCHONDRIAL CARRIER PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003387.1|UniProtKB=W5M6J7 W5M6J7 EDN3 PTHR13874:SF11 ENDOTHELIN ENDOTHELIN-3 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;positive regulation of catalytic activity#GO:0043085;system process#GO:0003008;positive regulation of molecular function#GO:0044093;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;regulation of systemic arterial blood pressure#GO:0003073;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;circulatory system process#GO:0003013;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of blood pressure#GO:0008217;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular monoatomic ion homeostasis#GO:0006873;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Big ET1-4#P00574 LEPOC|Ensembl=ENSLOCG00000005321.1|UniProtKB=W5MDF6 W5MDF6 PTHR46117:SF2 FI24210P1 UPSTREAM STIMULATORY FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 PDGF signaling pathway#P00047>c-fos#P01145 LEPOC|Ensembl=ENSLOCG00000006912.1|UniProtKB=W5MIZ9 W5MIZ9 PTHR12300:SF39 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996 supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;microtubule#GO:0005874;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006048.1|UniProtKB=W5MFZ3 W5MFZ3 PTHR22168:SF7 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26-LIKE LEPOC|Ensembl=ENSLOCG00000004445.1|UniProtKB=W5MAA1 W5MAA1 PTHR47385:SF10 CALPONIN TRANSGELIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012802.1|UniProtKB=W5N547 W5N547 PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005007.1|UniProtKB=W5MCB8 W5MCB8 PTHR46252:SF4 BRORIN FAMILY MEMBER BRORIN regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;monoatomic ion channel complex#GO:0034702;extracellular region#GO:0005576;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002122.1|UniProtKB=W5M2C5 W5M2C5 PTHR47958:SF32 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000007002.1|UniProtKB=W5MJB0 W5MJB0 PTHR12245:SF8 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006470.1|UniProtKB=W5MHI4 W5MHI4 PTHR22624:SF39 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4B cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;mitophagy#GO:0000423;protein modification process#GO:0036211;gene expression#GO:0010467;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009819.1|UniProtKB=W5MUD9 W5MUD9 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED LEPOC|Ensembl=ENSLOCG00000011229.1|UniProtKB=W5MZI6 W5MZI6 PTHR24028:SF288 CADHERIN-87A PROTOCADHERIN ALPHA-C2-LIKE-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000006271.1|UniProtKB=W5MGR5 W5MGR5 PTHR15127:SF33 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D protein binding#GO:0005515;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000005850.1|UniProtKB=W5MFA8 W5MFA8 PTHR44535:SF4 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK8 LEPOC|Ensembl=ENSLOCG00000002010.1|UniProtKB=W5M1T5 W5M1T5 PTHR15696:SF5 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG7 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002648.1|UniProtKB=W5M3Z9 W5M3Z9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010190.1|UniProtKB=W5MVT0 W5MVT0 PTHR12106:SF9 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015784.1|UniProtKB=W5NFM2 W5NFM2 PTHR23039:SF3 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 1 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000003897.1|UniProtKB=W5M8E3 W5M8E3 METTL1 PTHR23417:SF16 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001729.1|UniProtKB=W5M0U1 W5M0U1 PTHR14198:SF15 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016362.1|UniProtKB=W5NHU9 W5NHU9 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 LEPOC|Ensembl=ENSLOCG00000016415.1|UniProtKB=W5NI15 W5NI15 PTHR22950:SF207 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 2 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006344.1|UniProtKB=W5MGZ8 W5MGZ8 PTHR11654:SF509 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004651.1|UniProtKB=W5MB11 W5MB11 PTHR23048:SF3 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 1_3, SKELETAL MUSCLE ISOFORM supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007083.1|UniProtKB=W5MJL6 W5MJL6 PTHR23036:SF191 CYTOKINE RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006253.1|UniProtKB=W5MGQ0 W5MGQ0 PRRC2B PTHR14038:SF4 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2B cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005395.1|UniProtKB=W5MDP5 W5MDP5 PTHR11723:SF16 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-3 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id3#P06711 LEPOC|Ensembl=ENSLOCG00000015690.1|UniProtKB=W5NFB0 W5NFB0 CELF2 PTHR24012:SF699 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA splice site recognition#GO:0006376;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008609.1|UniProtKB=W5MQ11 W5MQ11 PTHR15128:SF0 TAL1 SCL INTERRUPTING LOCUS SCL-INTERRUPTING LOCUS PROTEIN cellular localization#GO:0051641;signal transduction#GO:0007165;mitotic spindle organization#GO:0007052;macromolecule localization#GO:0033036;smoothened signaling pathway#GO:0007224;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;protein localization#GO:0008104;localization#GO:0051179;response to stimulus#GO:0050896;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014817.1|UniProtKB=W5NC86 W5NC86 DNAJA4 PTHR43888:SF9 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 4 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012527.1|UniProtKB=W5N478 W5N478 PTHR11801:SF39 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;defense response#GO:0006952;signaling#GO:0023052;receptor signaling pathway via JAK-STAT#GO:0007259;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;regulation of macromolecule metabolic process#GO:0060255;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 LEPOC|Ensembl=ENSLOCG00000005653.1|UniProtKB=W5MEL6 W5MEL6 PTHR21381:SF3 ZGC:162297 SGC REGION PROTEIN SGCQ-RELATED LEPOC|Ensembl=ENSLOCG00000000031.1|UniProtKB=W5LV81 W5LV81 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009078.1|UniProtKB=W5MRQ7 W5MRQ7 PTHR46145:SF1 HEPARANASE INACTIVE HEPARANASE-2 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012335.1|UniProtKB=W5N3H2 W5N3H2 FAM187A PTHR32178:SF7 FAM187 IG-LIKE V-TYPE DOMAIN-CONTAINING PROTEIN FAM187A immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000017600.1|UniProtKB=W5NM46 W5NM46 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014871.1|UniProtKB=W5NCF4 W5NCF4 PTHR17490:SF10 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004279.1|UniProtKB=W5M9Q8 W5M9Q8 PTHR47972:SF43 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005545.1|UniProtKB=W5ME83 W5ME83 MYG1 PTHR11215:SF1 METAL DEPENDENT HYDROLASE - RELATED MYG1 EXONUCLEASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014661.1|UniProtKB=W5NBN4 W5NBN4 PTHR10501:SF63 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U1#P01479 LEPOC|Ensembl=ENSLOCG00000005279.1|UniProtKB=W5MDD0 W5MDD0 PTHR16220:SF0 WD REPEAT PROTEIN 8-RELATED WD REPEAT-CONTAINING PROTEIN WRAP73 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;mitotic sister chromatid segregation#GO:0000070;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002812.1|UniProtKB=W5M4R4 W5M4R4 PTHR46141:SF1 SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN SODIUM LEAK CHANNEL NALCN monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010412.1|UniProtKB=W5MWK9 W5MWK9 PTHR24390:SF162 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017359.1|UniProtKB=W5NLF5 W5NLF5 PTHR13447:SF2 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000213.1|UniProtKB=W5LVT5 W5LVT5 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014844.1|UniProtKB=W5NCC6 W5NCC6 PTHR13817:SF123 TITIN NEURAL CELL ADHESION MOLECULE L1.1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009496.1|UniProtKB=W5MT91 W5MT91 PTHR23048:SF44 MYOSIN LIGHT CHAIN 1, 3 ATRIAL MYOSIN LIGHT CHAIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015508.1|UniProtKB=W5NEM4 W5NEM4 PTHR11213:SF5 GLUCAGON-FAMILY NEUROPEPTIDE VIP PEPTIDES neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transport#GO:0006810;regulation of localization#GO:0032879;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;secretion#GO:0046903;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of protein localization#GO:0032880 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 neuropeptide#PC00162;intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000007806.1|UniProtKB=W5MM70 W5MM70 PTHR13531:SF14 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 17 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000012535.1|UniProtKB=W5N480 W5N480 PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011823.1|UniProtKB=W5N1N5 W5N1N5 PTHR23121:SF10 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 4A transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008654.1|UniProtKB=W5MQ64 W5MQ64 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016893.1|UniProtKB=W5NJS3 W5NJS3 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000006153.1|UniProtKB=W5MGC3 W5MGC3 PTHR46147:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 SET-BINDING PROTEIN N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;histone H3K4 methyltransferase activity#GO:0042800;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000003429.1|UniProtKB=W5M6Q3 W5M6Q3 C18orf54 PTHR35079:SF1 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015643.1|UniProtKB=W5NF48 W5NF48 PTHR12563:SF15 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 2, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 negative regulation of gene expression#GO:0010629;phospholipid biosynthetic process#GO:0008654;regulatory ncRNA processing#GO:0070918;gene expression#GO:0010467;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;triglyceride biosynthetic process#GO:0019432;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;piRNA processing#GO:0034587;regulation of cellular process#GO:0050794;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;fatty acid metabolic process#GO:0006631;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;glycerol-3-phosphate metabolic process#GO:0006072;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013272.1|UniProtKB=W5N6X6 W5N6X6 PTPRD PTHR19134:SF430 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE DELTA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cell junction organization#GO:0034330;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010144.1|UniProtKB=W5MVK8 W5MVK8 PTHR45882:SF1 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 LEPOC|Ensembl=ENSLOCG00000005040.1|UniProtKB=W5MCG5 W5MCG5 PTHR23157:SF24 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GOLGIN SUBFAMILY A MEMBER 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009952.1|UniProtKB=W5MUW1 W5MUW1 PTHR46791:SF13 EXPRESSED PROTEIN CLR5 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013785.1|UniProtKB=W5N8P7 W5N8P7 PTHR15876:SF8 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008827.1|UniProtKB=W5MQU3 W5MQU3 PTHR22504:SF4 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000005435.1|UniProtKB=W5MDV5 W5MDV5 PTHR45854:SF1 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000005839.1|UniProtKB=W5MF89 W5MF89 PTHR24409:SF438 ZINC FINGER PROTEIN 142 PLAG1 LIKE ZINC FINGER 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002414.1|UniProtKB=W5M373 W5M373 PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glucosidase#PC00108;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008993.1|UniProtKB=W5MRE7 W5MRE7 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 deacetylase#PC00087;hydrolase#PC00121 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 LEPOC|Ensembl=ENSLOCG00000003262.1|UniProtKB=W5M649 W5M649 PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI TRANSAMIDASE COMPONENT PIG-T lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000006643.1|UniProtKB=W5MI34 W5MI34 PTHR11811:SF25 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070 LEPOC|Ensembl=ENSLOCG00000012718.1|UniProtKB=W5N4U3 W5N4U3 PTHR47966:SF66 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSINOGEN C hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000142.1|UniProtKB=W5LVJ9 W5LVJ9 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000009813.1|UniProtKB=W5MUE4 W5MUE4 PTHR13817:SF84 TITIN CONTACTIN 3 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004976.1|UniProtKB=W5MC81 W5MC81 LLGL1 PTHR10241:SF21 LETHAL 2 GIANT LARVAE PROTEIN LETHAL(2) GIANT LARVAE PROTEIN HOMOLOG 1 nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;myosin binding#GO:0017022;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;binding#GO:0005488;syntaxin binding#GO:0019905;protein binding#GO:0005515;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;SNARE binding#GO:0000149 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of spindle orientation#GO:0051294;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of Notch signaling pathway#GO:0008593;Golgi to plasma membrane transport#GO:0006893;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;secretion by cell#GO:0032940;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015786.1|UniProtKB=W5NFM3 W5NFM3 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 cell division#GO:0051301;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;developmental process#GO:0032502;multicellular organism development#GO:0007275;activation of GTPase activity#GO:0090630;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;nervous system development#GO:0007399;mitotic cell cycle process#GO:1903047;positive regulation of hydrolase activity#GO:0051345;system development#GO:0048731;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;anatomical structure development#GO:0048856;biological regulation#GO:0065007;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;regulation of hydrolase activity#GO:0051336;cytokinesis#GO:0000910 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014023.1|UniProtKB=W5N9H6 W5N9H6 CEP135 PTHR23159:SF18 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN OF 135 KDA cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;centriole assembly#GO:0098534;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014812.1|UniProtKB=W5NC79 W5NC79 HIPK4 PTHR24058:SF46 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 4 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010409.1|UniProtKB=W5MWL6 W5MWL6 ITPA PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 Thiamin metabolism#P02780>Nucleoside triphosphatase#P03180 LEPOC|Ensembl=ENSLOCG00000008124.1|UniProtKB=W5MNB1 W5MNB1 PTHR10161:SF29 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 tissue remodeling#GO:0048771;bone remodeling#GO:0046849;tissue homeostasis#GO:0001894;bone resorption#GO:0045453;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;anatomical structure homeostasis#GO:0060249 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017924.1|UniProtKB=W5NN18 W5NN18 PTHR24072:SF306 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOH GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 small GTPase#PC00208 Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;FGF signaling pathway#P00021>Rac#P00645 LEPOC|Ensembl=ENSLOCG00000006239.1|UniProtKB=W5MGM6 W5MGM6 PTHR24173:SF16 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 24 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012546.1|UniProtKB=W5N491 W5N491 PTHR10336:SF85 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN PHOSPHOINOSITIDE PHOSPHOLIPASE C hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000017487.1|UniProtKB=W5NLT3 W5NLT3 PTHR24231:SF45 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008364.1|UniProtKB=W5MP49 W5MP49 PTHR28578:SF2 MITOTIC-SPINDLE ORGANIZING PROTEIN 2A-RELATED MITOTIC-SPINDLE ORGANIZING PROTEIN 2 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000004079.1|UniProtKB=W5M953 W5M953 PTHR10684:SF2 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;nuclear receptor binding#GO:0016922;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000000385.1|UniProtKB=W5LWB3 W5LWB3 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012401.1|UniProtKB=W5N3Q9 W5N3Q9 GPX2 PTHR11592:SF36 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 2 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016847.1|UniProtKB=W5NJL5 W5NJL5 PTHR45689:SF4 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;regulation of membrane depolarization#GO:0003254;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005689.1|UniProtKB=W5MEQ9 W5MEQ9 PTHR33767:SF2 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of gene expression#GO:0010628;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cytokine production#GO:0001819;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cytokine production#GO:0001817;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000010753.1|UniProtKB=W5MXR6 W5MXR6 PTHR45701:SF12 SYNAPTOBREVIN FAMILY MEMBER SI:CH73-234B20.5 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;regulation of body fluid levels#GO:0050878;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;vesicle organization#GO:0016050;multicellular organismal process#GO:0032501;organelle fusion#GO:0048284 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001913.1|UniProtKB=W5M1K5 W5M1K5 PTHR15720:SF12 GREB1-RELATED GREB1-LIKE PROTEIN system development#GO:0048731;multicellular organismal process#GO:0032501;kidney development#GO:0001822;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000005472.1|UniProtKB=W5MDZ0 W5MDZ0 PTHR24347:SF394 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 LEPOC|Ensembl=ENSLOCG00000018243.1|UniProtKB=W5NNY5 W5NNY5 NANOS1 PTHR12887:SF11 NANOS PROTEIN NANOS HOMOLOG 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;oogenesis#GO:0048477;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001770.1|UniProtKB=W5M100 W5M100 PTHR43788:SF10 DNA2/NAM7 HELICASE FAMILY MEMBER HELICASE WITH ZINC FINGER 2, TRANSCRIPTIONAL COACTIVATOR catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008258.1|UniProtKB=W5MNT4 W5MNT4 PTHR24416:SF533 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002347.1|UniProtKB=W5M2Z2 W5M2Z2 PTHR25465:SF32 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011774.1|UniProtKB=W5N1H5 W5N1H5 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008662.1|UniProtKB=W5MQ81 W5MQ81 PTHR46035:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 4 TETRATRICOPEPTIDE REPEAT PROTEIN 4 protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;Hsp90 protein binding#GO:0051879 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005756.1|UniProtKB=W5MEZ5 W5MEZ5 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006376.1|UniProtKB=W5MH38 W5MH38 PTHR19871:SF29 BETA TRANSDUCIN-RELATED PROTEIN NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2-LIKE LEPOC|Ensembl=ENSLOCG00000015368.1|UniProtKB=W5NE52 W5NE52 PTHR12114:SF1 PARVIN GAMMA-PARVIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;substrate adhesion-dependent cell spreading#GO:0034446;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012976.1|UniProtKB=W5N5S6 W5N5S6 PTHR24347:SF379 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE FAMILY MEMBER 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010927.1|UniProtKB=W5MYE1 W5MYE1 PTHR11690:SF298 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003157.1|UniProtKB=W5M5R9 W5M5R9 PTHR19143:SF156 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-1 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-1#P00248 LEPOC|Ensembl=ENSLOCG00000006282.1|UniProtKB=W5MGT0 W5MGT0 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;mitotic DNA replication checkpoint signaling#GO:0033314;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of mitotic cell cycle#GO:0045930;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000001644.1|UniProtKB=W5M0J3 W5M0J3 PTHR31333:SF6 PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER MUM1 LIKE 1 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015101.1|UniProtKB=W5ND82 W5ND82 SLC9A6 PTHR10110:SF94 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 6 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018057.1|UniProtKB=W5NNE9 W5NNE9 PTHR15478:SF12 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 3 positive regulation of apoptotic process#GO:0043065;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 LEPOC|Ensembl=ENSLOCG00000002201.1|UniProtKB=W5M2J0 W5M2J0 PTHR10218:SF233 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF) SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;system process#GO:0003008;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;dopamine receptor signaling pathway#GO:0007212;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;response to organic substance#GO:0010033;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;nervous system process#GO:0050877;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gsalpha#P00705 LEPOC|Ensembl=ENSLOCG00000008846.1|UniProtKB=W5MQX0 W5MQX0 PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011136.1|UniProtKB=W5MZ62 W5MZ62 PTHR31454:SF2 ACTIVE REGULATOR OF SIRT1 ACTIVE REGULATOR OF SIRT1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009658.1|UniProtKB=W5MTU4 W5MTU4 PTHR46134:SF3 DRONGO, ISOFORM F ARFGAP WITH FG REPEATS 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011343.1|UniProtKB=W5MZY7 W5MZY7 PTHR10117:SF9 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 7 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;fertilization#GO:0009566;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;single fertilization#GO:0007338;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;reproduction#GO:0000003;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;sexual reproduction#GO:0019953;reproductive process#GO:0022414;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000012356.1|UniProtKB=W5N3J7 W5N3J7 ARL10 PTHR46724:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED ADP RIBOSYLATION FACTOR LIKE GTPASE 10 LEPOC|Ensembl=ENSLOCG00000005936.1|UniProtKB=W5MFK9 W5MFK9 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013808.1|UniProtKB=W5N8S0 W5N8S0 PTHR13016:SF0 AMMECR1 HOMOLOG AMME SYNDROME CANDIDATE GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000012639.1|UniProtKB=W5N4K0 W5N4K0 PTHR24050:SF19 PA14 DOMAIN-CONTAINING PROTEIN NEPHRONECTIN LEPOC|Ensembl=ENSLOCG00000005195.1|UniProtKB=W5MD19 W5MD19 PTHR24027:SF89 CADHERIN-23 CADHERIN-5 cell adhesion molecule binding#GO:0050839;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;tight junction#GO:0070160;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;bicellular tight junction#GO:0005923;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000003188.1|UniProtKB=W5M5W3 W5M5W3 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL lipid binding#GO:0008289;binding#GO:0005488 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005468.1|UniProtKB=W5MDZ9 W5MDZ9 PTHR24418:SF42 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LYN protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;neurogenesis#GO:0022008;activation of immune response#GO:0002253;cell projection organization#GO:0030030;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;regulation of signaling#GO:0023051;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;positive regulation of immune response#GO:0050778;cell differentiation#GO:0030154;DNA damage response#GO:0006974;response to biotic stimulus#GO:0009607;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;immune system development#GO:0002520;multicellular organism development#GO:0007275;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;defense response to other organism#GO:0098542;leukocyte differentiation#GO:0002521;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;generation of neurons#GO:0048699;cellular response to stress#GO:0033554;immune response-activating signaling pathway#GO:0002757 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Yes#P00476;Parkinson disease#P00049>Src kinase#P01230;B cell activation#P00010>Lyn#P00374;CCKR signaling map#P06959>LYN#P07141 LEPOC|Ensembl=ENSLOCG00000011688.1|UniProtKB=W5N154 W5N154 SPOP PTHR24413:SF97 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;regulation of protein metabolic process#GO:0051246;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000960.1|UniProtKB=W5LY63 W5LY63 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006247.1|UniProtKB=W5MGN7 W5MGN7 PTHR24089:SF196 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A23 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007760.1|UniProtKB=W5MM19 W5MM19 PTHR45655:SF10 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 88E lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000002353.1|UniProtKB=W5M306 W5M306 PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002532.1|UniProtKB=W5M3L1 W5M3L1 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005960.1|UniProtKB=W5MFN7 W5MFN7 PTHR12011:SF435 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009699.1|UniProtKB=W5MTY4 W5MTY4 PTHR45617:SF175 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000906.1|UniProtKB=W5LXZ7 W5LXZ7 PTHR15088:SF0 NUCLEAR FACTOR RIP140 NUCLEAR RECEPTOR-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003134.1|UniProtKB=W5M5P3 W5M5P3 PTHR46054:SF2 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;RNA localization#GO:0006403;axo-dendritic transport#GO:0008088;cell differentiation#GO:0030154;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;reproductive process#GO:0022414;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;protein localization to synapse#GO:0035418;multicellular organism reproduction#GO:0032504;cellular process#GO:0009987;transport along microtubule#GO:0010970;protein localization#GO:0008104;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;localization#GO:0051179;microtubule-based transport#GO:0099111;reproduction#GO:0000003;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;sexual reproduction#GO:0019953;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;cell body#GO:0044297;neuron projection#GO:0043005;cytoplasmic stress granule#GO:0010494;cell projection#GO:0042995;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011302.1|UniProtKB=W5MZT1 W5MZT1 ST6GALNAC2 PTHR45941:SF5 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000000174.1|UniProtKB=W5LVN8 W5LVN8 C1orf232 PTHR35663:SF3 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED GENE, 30191-RELATED LEPOC|Ensembl=ENSLOCG00000001701.1|UniProtKB=W5M0S6 W5M0S6 PTHR21422:SF9 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000006659.1|UniProtKB=W5MI33 W5MI33 PTHR22770:SF35 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein binding#GO:0032182;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010047.1|UniProtKB=W5MV90 W5MV90 PTHR24046:SF2 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010678.1|UniProtKB=W5MXH2 W5MXH2 PTHR15508:SF4 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-LIKE 1 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000010939.1|UniProtKB=W5MYF4 W5MYF4 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000004223.1|UniProtKB=W5M9J0 W5M9J0 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007133.1|UniProtKB=W5MJS3 W5MJS3 PTHR46092:SF2 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-D11 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011166.1|UniProtKB=W5MZB6 W5MZB6 PTHR47634:SF4 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;protein-containing complex assembly#GO:0065003;RNA processing#GO:0006396;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;regulation of mRNA processing#GO:0050684;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;peptidyl-serine modification#GO:0018209;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005329.1|UniProtKB=W5MDG3 W5MDG3 PTHR12411:SF965 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L.1 cysteine-type peptidase activity#GO:0008234;peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;positive regulation of apoptotic signaling pathway#GO:2001235;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016928.1|UniProtKB=W5NJW8 W5NJW8 RARS2 PTHR11956:SF11 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015752.1|UniProtKB=W5NFI5 W5NFI5 PTHR15989:SF5 VEZATIN VEZATIN cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002263.1|UniProtKB=W5M2P4 W5M2P4 SYT8 PTHR10024:SF249 SYNAPTOTAGMIN SYNAPTOTAGMIN-8 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000006289.1|UniProtKB=W5MGT8 W5MGT8 PTHR10972:SF215 OXYSTEROL-BINDING PROTEIN-RELATED PH DOMAIN-CONTAINING PROTEIN binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015796.1|UniProtKB=W5NFP2 W5NFP2 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;catalytic step 2 spliceosome#GO:0071013;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000008807.1|UniProtKB=W5MQQ9 W5MQQ9 PTHR45767:SF1 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CCKR signaling map#P06959>FOXO1#P07167;PI3 kinase pathway#P00048>FOXO#P01198;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 LEPOC|Ensembl=ENSLOCG00000016683.1|UniProtKB=W5NJ05 W5NJ05 DENND2A PTHR15288:SF3 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2A localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007356.1|UniProtKB=W5MKK2 W5MKK2 PTHR33776:SF3 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN PHD-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006724.1|UniProtKB=W5MIC1 W5MIC1 PTHR11036:SF10 SEMAPHORIN SEMAPHORIN-6B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;axon guidance#GO:0007411;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell communication#GO:0007154;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015008.1|UniProtKB=W5NCX1 W5NCX1 PTHR11782:SF29 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 4 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000012632.1|UniProtKB=W5N4J3 W5N4J3 PTHR11100:SF20 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-2, MEMBRANE-BOUND ISOFORM protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000000187.1|UniProtKB=W5LVQ1 W5LVQ1 PTHR48112:SF12 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B1-LIKE 1-RELATED regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HMG box transcription factor#PC00024 p53 pathway#P00059>HMG1#P04619 LEPOC|Ensembl=ENSLOCG00000006820.1|UniProtKB=W5MIQ3 W5MIQ3 PTHR11537:SF184 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;presynaptic membrane#GO:0042734;cell leading edge#GO:0031252;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;distal axon#GO:0150034;postsynapse#GO:0098794;cell projection#GO:0042995;membrane protein complex#GO:0098796;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell projection membrane#GO:0031253;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016207.1|UniProtKB=W5NH68 W5NH68 PTHR15919:SF13 DAPPER-RELATED DAPPER HOMOLOG 2 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010671.1|UniProtKB=W5MXG2 W5MXG2 PTHR23192:SF7 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014238.1|UniProtKB=W5NA73 W5NA73 PTHR10174:SF200 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINALDEHYDE-BINDING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008622.1|UniProtKB=W5MQ26 W5MQ26 PTHR24012:SF702 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016883.1|UniProtKB=W5NJR0 W5NJR0 GCM1 PTHR12414:SF6 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008045.1|UniProtKB=W5MN08 W5MN08 PTHR22779:SF2 SD17342P TRANSMEMBRANE PROTEIN 170A endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017052.1|UniProtKB=W5NKB5 W5NKB5 PTHR16121:SF0 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004182.1|UniProtKB=W5M9D0 W5M9D0 GBGT1 PTHR10462:SF49 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015591.1|UniProtKB=W5NEY7 W5NEY7 PTHR12745:SF12 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000016414.1|UniProtKB=W5NI12 W5NI12 PTHR23032:SF13 BRO1 DOMAIN-CONTAINING PROTEIN BROX BRO1 DOMAIN-CONTAINING PROTEIN BROX LEPOC|Ensembl=ENSLOCG00000012231.1|UniProtKB=W5N334 W5N334 PTHR11814:SF31 SULFATE TRANSPORTER SULFATE ANION TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002097.1|UniProtKB=W5M264 W5M264 PTHR13265:SF2 THO COMPLEX SUBUNIT 1 THO COMPLEX SUBUNIT 1 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016357.1|UniProtKB=W5NHT8 W5NHT8 PTHR10983:SF2 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED ACYL-COA:LYSOPHOSPHATIDYLGLYCEROL ACYLTRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000001085.1|UniProtKB=W5LYL7 W5LYL7 UBN1 PTHR21669:SF12 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007665.1|UniProtKB=W5MLP9 W5MLP9 PTHR11347:SF91 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000002002.1|UniProtKB=W5M1S0 W5M1S0 PTHR22804:SF6 AGGRECAN/VERSICAN PROTEOGLYCAN VERSICAN CORE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000012269.1|UniProtKB=W5N390 W5N390 PTHR14002:SF13 ENDOGLIN/TGF-BETA RECEPTOR TYPE III BETA-TECTORIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010034.1|UniProtKB=W5MV68 W5MV68 NSMCE2 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014698.1|UniProtKB=W5NBT5 W5NBT5 PTHR12673:SF79 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;filopodium assembly#GO:0046847;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015444.1|UniProtKB=W5NEF3 W5NEF3 PTHR10183:SF385 CALPAIN CALPAIN-9 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000009651.1|UniProtKB=W5MTT4 W5MTT4 PTHR11003:SF346 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008990.1|UniProtKB=W5MRE3 W5MRE3 PTHR10671:SF106 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS INTRINSIC MEMBRANE PROTEIN 2.2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016813.1|UniProtKB=W5NJI4 W5NJI4 PTHR24351:SF213 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000004413.1|UniProtKB=W5MA79 W5MA79 PTHR24040:SF7 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 3 LEPOC|Ensembl=ENSLOCG00000005160.1|UniProtKB=W5MCV0 W5MCV0 PTHR31296:SF1 UPF0565 PROTEIN C2ORF69 MITOCHONDRIAL PROTEIN C2ORF69 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001873.1|UniProtKB=W5M1B2 W5M1B2 PTHR13624:SF3 RE42071P TRANSMEMBRANE PROTEIN 161B LEPOC|Ensembl=ENSLOCG00000009436.1|UniProtKB=W5MT22 W5MT22 PTHR31859:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39A LEPOC|Ensembl=ENSLOCG00000006749.1|UniProtKB=W5MIF3 W5MIF3 PTHR13703:SF68 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013569.1|UniProtKB=W5N7X0 W5N7X0 PTHR24215:SF29 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE RICH PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012959.1|UniProtKB=W5N5U0 W5N5U0 PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 Ionotropic glutamate receptor pathway#P00037>NSF#P01020;Synaptic vesicle trafficking#P05734>NSF#P05774 LEPOC|Ensembl=ENSLOCG00000011036.1|UniProtKB=W5MYV5 W5MYV5 PTHR46806:SF2 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 synapse#GO:0045202;postsynaptic membrane#GO:0045211;neuron projection#GO:0043005;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;axon#GO:0030424;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003989.1|UniProtKB=W5M8R6 W5M8R6 PTHR10684:SF3 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;nuclear receptor binding#GO:0016922;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Gonadotropin-releasing hormone receptor pathway#P06664>Ncoa3#P06719 LEPOC|Ensembl=ENSLOCG00000014920.1|UniProtKB=W5NCL3 W5NCL3 PTHR43243:SF20 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 3 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015985.1|UniProtKB=W5NGC3 W5NGC3 PTHR11106:SF104 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;cellular response to stimulus#GO:0051716;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;glycosyl compound metabolic process#GO:1901657;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006732.1|UniProtKB=W5MIC5 W5MIC5 PTHR11932:SF76 CULLIN CULLIN-5 enzyme binding#GO:0019899;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007464.1|UniProtKB=W5ML02 W5ML02 PTHR11709:SF233 MULTI-COPPER OXIDASE FERROXIDASE HEPHL1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005761.1|UniProtKB=W5MEZ9 W5MEZ9 PTHR46770:SF1 HOMEOBOX PROTEIN ORTHOPEDIA HOMEOBOX PROTEIN ORTHOPEDIA nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001620.1|UniProtKB=W5M0F9 W5M0F9 PTHR27001:SF931 OS01G0253100 PROTEIN OS11G0664100 PROTEIN macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016517.1|UniProtKB=W5NIE3 W5NIE3 PTHR34832:SF1 CENTROMERE PROTEIN W CENTROMERE PROTEIN W cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;kinetochore organization#GO:0051383;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;non-membrane-bounded organelle assembly#GO:0140694;kinetochore assembly#GO:0051382 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nucleoplasm#GO:0005654;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000005944.1|UniProtKB=W5MFM4 W5MFM4 PTHR11629:SF22 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 2 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018041.1|UniProtKB=W5NND3 W5NND3 SERTM1 PTHR35660:SF1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000044.1|UniProtKB=W5LV95 W5LV95 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003791.1|UniProtKB=W5M834 W5M834 PTHR23235:SF154 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002336.1|UniProtKB=W5M2X4 W5M2X4 PTHR31004:SF3 TRANSMEMBRANE PROTEIN 79 TRANSMEMBRANE PROTEIN 79 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;vacuole#GO:0005773;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000011760.1|UniProtKB=W5N1F2 W5N1F2 PTHR11615:SF124 NITRATE, FORMATE, IRON DEHYDROGENASE NUCLEAR PRELAMIN A RECOGNITION FACTOR protein binding#GO:0005515;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intermediate filament#GO:0005882;intracellular organelle lumen#GO:0070013;intermediate filament cytoskeleton#GO:0045111;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;nuclear periphery#GO:0034399;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008728.1|UniProtKB=W5MQG0 W5MQG0 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010304.1|UniProtKB=W5MW63 W5MW63 PTHR28388:SF1 TRANSMEMBRANE PROTEIN 237 TRANSMEMBRANE PROTEIN 237 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000006829.1|UniProtKB=W5MIP6 W5MIP6 PTHR46205:SF2 LOQUACIOUS, ISOFORM B INTERFERON-INDUCIBLE DOUBLE-STRANDED RNA-DEPENDENT PROTEIN KINASE ACTIVATOR A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;endoribonuclease complex#GO:1902555;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>PACT#P00280 LEPOC|Ensembl=ENSLOCG00000007761.1|UniProtKB=W5MM14 W5MM14 PTHR11921:SF29 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL cellular respiration#GO:0045333;aerobic respiration#GO:0009060;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015361.1|UniProtKB=W5NE43 W5NE43 PTHR45701:SF8 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002889.1|UniProtKB=W5M4U4 W5M4U4 MUTYH PTHR42944:SF1 ADENINE DNA GLYCOSYLASE ADENINE DNA GLYCOSYLASE nucleic acid binding#GO:0003676;DNA N-glycosylase activity#GO:0019104;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;damaged DNA binding#GO:0003684;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;double-stranded DNA binding#GO:0003690 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000014100.1|UniProtKB=W5N9R3 W5N9R3 NDUFB1 PTHR15222:SF2 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013514.1|UniProtKB=W5N7R6 W5N7R6 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010505.1|UniProtKB=W5MWW7 W5MWW7 PTHR12450:SF14 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 GLYCOSAMINOGLYCAN XYLOSYLKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007967.1|UniProtKB=W5MMS0 W5MMS0 PTHR24117:SF8 AGAP007537-PB BCL-6 COREPRESSOR molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003092.1|UniProtKB=W5M5H8 W5M5H8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005512.1|UniProtKB=W5ME46 W5ME46 CCDC14 PTHR22367:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;centriolar satellite#GO:0034451;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010057.1|UniProtKB=W5MV91 W5MV91 PTHR16238:SF7 GEM-ASSOCIATED PROTEIN 8 GEM-ASSOCIATED PROTEIN 8 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006136.1|UniProtKB=W5MGA5 W5MGA5 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007523.1|UniProtKB=W5ML67 W5ML67 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010377.1|UniProtKB=W5MWF9 W5MWF9 PTHR18902:SF25 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004920.1|UniProtKB=W5MC10 W5MC10 PTHR11849:SF216 ETS TRANSCRIPTIONAL REGULATOR ERG transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000005565.1|UniProtKB=W5MEB1 W5MEB1 PTHR15742:SF1 GIRDIN PROTEIN SOGA1 LEPOC|Ensembl=ENSLOCG00000012195.1|UniProtKB=W5N2Y9 W5N2Y9 PTHR15528:SF12 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-BETA molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010565.1|UniProtKB=W5MX34 W5MX34 PTHR12439:SF32 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE B catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 LEPOC|Ensembl=ENSLOCG00000014921.1|UniProtKB=W5NCL6 W5NCL6 PTHR15653:SF1 STRIATIN STRIATIN-4 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;protein phosphatase binding#GO:0019903;binding#GO:0005488 dendrite#GO:0030425;dendritic tree#GO:0097447;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000015124.1|UniProtKB=W5NDA5 W5NDA5 PTHR11471:SF57 TUMOR NECROSIS FACTOR FAMILY MEMBER CD154 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015273.1|UniProtKB=W5NDT3 W5NDT3 PTHR12611:SF4 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015114.1|UniProtKB=W5ND99 W5ND99 PTHR11730:SF30 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE C inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013820.1|UniProtKB=W5N8T1 W5N8T1 PTHR10846:SF36 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of signaling#GO:0023051;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;negative regulation of signaling#GO:0023057;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009584.1|UniProtKB=W5MTJ9 W5MTJ9 PTHR28567:SF4 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53C cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000897.1|UniProtKB=W5LXY7 W5LXY7 PTHR10339:SF25 ADP-RIBOSYLTRANSFERASE SECRETED EXOENZYME S transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001656.1|UniProtKB=W5M0S1 W5M0S1 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5-RELATED cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000001980.1|UniProtKB=W5M1N2 W5M1N2 PTHR28611:SF1 NORRIN NORRIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000001154.1|UniProtKB=W5LYU2 W5LYU2 PTHR22599:SF10 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3A protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000007571.1|UniProtKB=W5MLE0 W5MLE0 MED13L PTHR48249:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13-LIKE transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006056.1|UniProtKB=W5MG01 W5MG01 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 21 binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;amide binding#GO:0033218 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000077.1|UniProtKB=W5LVD1 W5LVD1 PTHR24418:SF23 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRMS protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000005220.1|UniProtKB=W5MD23 W5MD23 PTHR12812:SF3 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012798.1|UniProtKB=W5N545 W5N545 PTHR46458:SF2 BLR2807 PROTEIN X GLOBIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004732.1|UniProtKB=W5MBB2 W5MBB2 PTHR31281:SF0 PROTEIN FAM219A PROTEIN FAM219A LEPOC|Ensembl=ENSLOCG00000003941.1|UniProtKB=W5M8N7 W5M8N7 PTHR10190:SF11 EYES ABSENT EYES ABSENT HOMOLOG 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of DNA repair#GO:0045739;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of DNA repair#GO:0006282;regulation of biological process#GO:0050789;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of response to stress#GO:0080134;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004065.1|UniProtKB=W5M904 W5M904 EARS2 PTHR43311:SF2 GLUTAMATE--TRNA LIGASE GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 LEPOC|Ensembl=ENSLOCG00000014833.1|UniProtKB=W5NCA8 W5NCA8 PTHR12283:SF3 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN cation binding#GO:0043169;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;aminoacyltransferase activity#GO:0016755;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000766.1|UniProtKB=W5LXN4 W5LXN4 EPHA8 PTHR46877:SF7 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 8 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011369.1|UniProtKB=W5N012 W5N012 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003115.1|UniProtKB=W5M5M9 W5M5M9 PTHR24269:SF26 KREMEN PROTEIN KRINGLE-CONTAINING PROTEIN MARKING THE EYE AND THE NOSE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005987.1|UniProtKB=W5MFT4 W5MFT4 PTHR24099:SF7 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED CARDIOMYOPATHY-ASSOCIATED PROTEIN 5 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011226.1|UniProtKB=W5MZI0 W5MZI0 PTHR24028:SF307 CADHERIN-87A PROTOCADHERIN BETA-15-LIKE ISOFORM X1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000008811.1|UniProtKB=W5MQR2 W5MQR2 PTHR45973:SF12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN REGULATORY COMPLEX SUBUNIT 3 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000004400.1|UniProtKB=W5MA71 W5MA71 PTHR21245:SF5 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000635.1|UniProtKB=W5LX45 W5LX45 PTHR12210:SF187 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013789.1|UniProtKB=W5N8P6 W5N8P6 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000010204.1|UniProtKB=W5MVT3 W5MVT3 PTHR15106:SF2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016316.1|UniProtKB=W5NHN4 W5NHN4 PTHR23083:SF475 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7A lipid metabolic process#GO:0006629;cellular localization#GO:0051641;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004944.1|UniProtKB=W5MC98 W5MC98 PTHR45623:SF6 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 5 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006550.1|UniProtKB=W5MHQ7 W5MHQ7 PTHR11267:SF204 T-BOX PROTEIN-RELATED SPADETAIL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000007972.1|UniProtKB=W5MMS9 W5MMS9 AMY1C PTHR43447:SF49 ALPHA-AMYLASE ALPHA-AMYLASE amylase#PC00048;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006083.1|UniProtKB=W5MG44 W5MG44 PTHR11952:SF6 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE-LIKE PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000001267.1|UniProtKB=W5LZA5 W5LZA5 PTHR12702:SF3 SEC15 EXOCYST COMPLEX COMPONENT 6B localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006654.1|UniProtKB=W5MI23 W5MI23 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000015805.1|UniProtKB=W5NFP7 W5NFP7 PTHR11814:SF19 SULFATE TRANSPORTER CHLORIDE ANION EXCHANGER inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004124.1|UniProtKB=W5M970 W5M970 PTHR24056:SF243 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 8 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002348.1|UniProtKB=W5M2Z9 W5M2Z9 PTHR35083:SF3 RGD1565685 PROTEIN SI:CH211-91P5.3 LEPOC|Ensembl=ENSLOCG00000000107.1|UniProtKB=W5LVF7 W5LVF7 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012944.1|UniProtKB=W5N5M8 W5N5M8 RAMAC PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED LEPOC|Ensembl=ENSLOCG00000011577.1|UniProtKB=W5N0R7 W5N0R7 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002763.1|UniProtKB=W5M4E2 W5M4E2 QPRT PTHR32179:SF3 NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;dicarboxylic acid metabolic process#GO:0043648;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008872.1|UniProtKB=W5MQZ7 W5MQZ7 PTHR11036:SF12 SEMAPHORIN SEMAPHORIN-6A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;axon guidance#GO:0007411;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell communication#GO:0007154;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010206.1|UniProtKB=W5MVT7 W5MVT7 PTHR13793:SF84 PHD FINGER PROTEINS E3 UBIQUITIN-PROTEIN LIGASE JADE-2 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005725.1|UniProtKB=W5MEV6 W5MEV6 PTHR12706:SF8 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 1 nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003172.1|UniProtKB=W5M5U3 W5M5U3 PTHR15301:SF10 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 2 PROTEIN sterol metabolic process#GO:0016125;cellular localization#GO:0051641;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;cholesterol metabolic process#GO:0008203;lipid biosynthetic process#GO:0008610;regulation of biological process#GO:0050789;steroid metabolic process#GO:0008202;regulation of cellular response to stress#GO:0080135;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;protein localization to endoplasmic reticulum#GO:0070972;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;alcohol metabolic process#GO:0006066;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;primary metabolic process#GO:0044238;protein localization#GO:0008104;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;negative regulation of signal transduction#GO:0009968;small molecule biosynthetic process#GO:0044283;cellular response to stress#GO:0033554;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;cellular response to lipid#GO:0071396;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;cellular response to organic cyclic compound#GO:0071407;cellular response to insulin stimulus#GO:0032869;protein localization to organelle#GO:0033365;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;SREBP signaling pathway#GO:0032933;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;sterol biosynthetic process#GO:0016126 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000015428.1|UniProtKB=W5NEC5 W5NEC5 PTHR20859:SF87 INTERFERON/INTERLEUKIN RECEPTOR CYTOKINE RECEPTOR FAMILY MEMBER B13-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011219.1|UniProtKB=W5MZH4 W5MZH4 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;spliceosomal tri-snRNP complex#GO:0097526;U4/U6 x U5 tri-snRNP complex#GO:0046540;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002830.1|UniProtKB=W5M4N0 W5M4N0 PTHR24061:SF0 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCT1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009363.1|UniProtKB=W5MSS1 W5MSS1 PTHR10352:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 4 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000014559.1|UniProtKB=W5NBA7 W5NBA7 PTHR43836:SF10 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE B methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;catecholamine metabolic process#GO:0006584;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007000.1|UniProtKB=W5MJB5 W5MJB5 PTHR12289:SF38 METAXIN RELATED METAXIN-2 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003899.1|UniProtKB=W5M8F5 W5M8F5 PTHR12097:SF0 SPLICING FACTOR 3B, SUBUNIT 1-RELATED SPLICING FACTOR 3B SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010844.1|UniProtKB=W5MY35 W5MY35 PTHR10663:SF337 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012692.1|UniProtKB=W5N4Q8 W5N4Q8 PTHR31940:SF2 SMALL KINETOCHORE-ASSOCIATED PROTEIN SMALL KINETOCHORE-ASSOCIATED PROTEIN nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;spindle organization#GO:0007051;mitotic sister chromatid segregation#GO:0000070 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;centriolar satellite#GO:0034451;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000002217.1|UniProtKB=W5M2H3 W5M2H3 PTHR13947:SF11 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLASPARTATE SYNTHETASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000012559.1|UniProtKB=W5N4A4 W5N4A4 PTHR12478:SF18 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 REGULATED IN DEVELOPMENT AND DNA DAMAGE RESPONSE 2 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006 LEPOC|Ensembl=ENSLOCG00000001203.1|UniProtKB=W5LZ14 W5LZ14 PTHR12801:SF62 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 1 HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000018286.1|UniProtKB=W5NP28 W5NP28 PTHR12002:SF182 CLAUDIN CLAUDIN-23-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000007328.1|UniProtKB=W5MKG6 W5MKG6 PTHR10845:SF32 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 13 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 LEPOC|Ensembl=ENSLOCG00000014566.1|UniProtKB=W5NBC0 W5NBC0 PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000009624.1|UniProtKB=W5MTQ6 W5MTQ6 ALDH1A1 PTHR11699:SF140 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE 1A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000006797.1|UniProtKB=W5MIK2 W5MIK2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004858.1|UniProtKB=W5MBS3 W5MBS3 PTHR19411:SF0 PROTEIN BUD31-RELATED PROTEIN BUD31 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016148.1|UniProtKB=W5NGY7 W5NGY7 PTHR24073:SF1221 DRAB5-RELATED RAS-RELATED PROTEIN RAB GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000004901.1|UniProtKB=W5MBY3 W5MBY3 PTHR11909:SF7 CASEIN KINASE-RELATED CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001279.1|UniProtKB=W5LZC0 W5LZC0 PTHR24346:SF47 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK2-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002043.1|UniProtKB=W5M1W2 W5M1W2 PTHR46061:SF1 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 LEPOC|Ensembl=ENSLOCG00000005955.1|UniProtKB=W5MFN2 W5MFN2 PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011738.1|UniProtKB=W5N1C3 W5N1C3 PTHR12532:SF0 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 LEPOC|Ensembl=ENSLOCG00000014624.1|UniProtKB=W5NBI8 W5NBI8 PTHR23257:SF755 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011771.1|UniProtKB=W5N1G8 W5N1G8 PTHR46513:SF5 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED PRO-EPIDERMAL GROWTH FACTOR signaling receptor activity#GO:0038023;molecular function activator activity#GO:0140677;Wnt-protein binding#GO:0017147;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGF#P00549;Gonadotropin-releasing hormone receptor pathway#P06664>EGF#P06745 LEPOC|Ensembl=ENSLOCG00000009320.1|UniProtKB=W5MSL4 W5MSL4 PTHR15721:SF2 KIAA0586 PROTEIN PROTEIN TALPID3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003628.1|UniProtKB=W5M7H1 W5M7H1 PTHR23281:SF23 MERLIN/MOESIN/EZRIN/RADIXIN NEUROFIBROMIN 2 cytoskeletal protein binding#GO:0008092;integrin binding#GO:0005178;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;actin binding#GO:0003779 negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of intracellular signal transduction#GO:1902531;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;regulation of organelle assembly#GO:1902115;negative regulation of cell population proliferation#GO:0008285;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;regulation of cell development#GO:0060284;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829 filopodium#GO:0030175;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;actin-based cell projection#GO:0098858;adherens junction#GO:0005912;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002032.1|UniProtKB=W5M1X2 W5M1X2 PTHR24223:SF187 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003640.1|UniProtKB=W5M7G1 W5M7G1 PTHR13874:SF9 ENDOTHELIN ENDOTHELIN-2 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;positive regulation of catalytic activity#GO:0043085;system process#GO:0003008;positive regulation of molecular function#GO:0044093;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;regulation of systemic arterial blood pressure#GO:0003073;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;circulatory system process#GO:0003013;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of blood pressure#GO:0008217;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular monoatomic ion homeostasis#GO:0006873;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576;Endothelin signaling pathway#P00019>Big ET1-4#P00574 LEPOC|Ensembl=ENSLOCG00000017942.1|UniProtKB=W5NN36 W5NN36 PTHR24368:SF1 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 1 head development#GO:0060322;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005804.1|UniProtKB=W5MF57 W5MF57 SLC5A10 PTHR11819:SF128 SOLUTE CARRIER FAMILY 5 SODIUM_MANNOSE COTRANSPORTER SLC5A10 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008490.1|UniProtKB=W5MPM1 W5MPM1 FYTTD1 PTHR21038:SF2 40-2-3 PROTEIN-RELATED UAP56-INTERACTING FACTOR nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010799.1|UniProtKB=W5MXY2 W5MXY2 PTHR13055:SF11 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000305.1|UniProtKB=W5LW35 W5LW35 PTHR11958:SF102 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012601.1|UniProtKB=W5N4G3 W5N4G3 PTHR11616:SF277 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007773.1|UniProtKB=W5MM29 W5MM29 PTHR12025:SF11 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR D molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;response to abiotic stimulus#GO:0009628;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to hypoxia#GO:0001666;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;positive regulation of leukocyte migration#GO:0002687;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of immune system process#GO:0002682;signaling#GO:0023052;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of response to external stimulus#GO:0032101;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of leukocyte chemotaxis#GO:0002690 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000007298.1|UniProtKB=W5MKD0 W5MKD0 PTHR10985:SF136 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000000127.1|UniProtKB=W5LVI2 W5LVI2 PTHR19143:SF425 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010993.1|UniProtKB=W5MYN7 W5MYN7 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015283.1|UniProtKB=W5NDU4 W5NDU4 PTHR15852:SF49 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG LEPOC|Ensembl=ENSLOCG00000005161.1|UniProtKB=W5MCV7 W5MCV7 PTHR10985:SF5 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009303.1|UniProtKB=W5MSJ1 W5MSJ1 AOPEP PTHR46627:SF1 AMINOPEPTIDASE O AMINOPEPTIDASE O intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001855.1|UniProtKB=W5M1B0 W5M1B0 PTHR45620:SF7 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE 2 RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012825.1|UniProtKB=W5N578 W5N578 PTHR45636:SF20 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010543.1|UniProtKB=W5MX08 W5MX08 FGF1 PTHR11486:SF86 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of kinase activity#GO:0033674;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000014606.1|UniProtKB=W5NBG9 W5NBG9 SAMD4B PTHR12515:SF9 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 LEPOC|Ensembl=ENSLOCG00000012582.1|UniProtKB=W5N4D3 W5N4D3 PTHR14074:SF7 HELICASE WITH DEATH DOMAIN-RELATED ATP-DEPENDENT RNA HELICASE DHX58 cation binding#GO:0043169;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;double-stranded RNA binding#GO:0003725 response to external biotic stimulus#GO:0043207;response to virus#GO:0009615;immune response-regulating signaling pathway#GO:0002764;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of signaling#GO:0023051;pattern recognition receptor signaling pathway#GO:0002221;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;regulation of immune system process#GO:0002682;defense response to virus#GO:0051607;intracellular receptor signaling pathway#GO:0030522;defense response#GO:0006952;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;defense response to other organism#GO:0098542;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010330.1|UniProtKB=W5MWA7 W5MWA7 PTHR11532:SF63 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE Z metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013594.1|UniProtKB=W5N807 W5N807 PTHR15633:SF2 NUCLEOLAR PROTEIN 11 NUCLEOLAR PROTEIN 11 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007804.1|UniProtKB=W5MM62 W5MM62 PTHR12027:SF76 WNT RELATED PROTEIN WNT-10B molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000009109.1|UniProtKB=W5MRY2 W5MRY2 PTHR24092:SF33 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IH ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013856.1|UniProtKB=W5N8Y0 W5N8Y0 PTHR45712:SF3 AGAP008170-PA OSTEOMODULIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000000516.1|UniProtKB=W5LWR4 W5LWR4 PTHR45013:SF1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011900.1|UniProtKB=W5N1Z9 W5N1Z9 PTHR18905:SF11 NINEIN NINEIN cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;centrosome localization#GO:0051642;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;microtubule nucleation#GO:0007020 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ciliary transition fiber#GO:0097539;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 PDGF signaling pathway#P00047>GSK3#P01153 LEPOC|Ensembl=ENSLOCG00000010166.1|UniProtKB=W5MVP1 W5MVP1 PTHR23255:SF63 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 signaling receptor activity#GO:0038023;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 LEPOC|Ensembl=ENSLOCG00000015293.1|UniProtKB=W5NDV5 W5NDV5 PTHR46343:SF3 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of multicellular organismal process#GO:0051239;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cell-cell adhesion#GO:0098609;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell adhesion#GO:0007155;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of synapse assembly#GO:0051965;regulation of cell migration#GO:0030334;positive regulation of cell migration#GO:0030335;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;positive regulation of cell motility#GO:2000147;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000012216.1|UniProtKB=W5N325 W5N325 PTHR20854:SF26 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 1 inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;organic hydroxy compound metabolic process#GO:1901615;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;signaling#GO:0023052;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003351.1|UniProtKB=W5M6E6 W5M6E6 PTHR10252:SF79 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DNA POLYMERASE EPSILON SUBUNIT 4 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular protein-containing complex#GO:0140535;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009850.1|UniProtKB=W5MUI2 W5MUI2 PTHR22591:SF2 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;actomyosin#GO:0042641;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002227.1|UniProtKB=W5M2K6 W5M2K6 PTHR24006:SF925 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016637.1|UniProtKB=W5NIU7 W5NIU7 PTHR24115:SF344 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF28P pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001129.1|UniProtKB=W5LYS3 W5LYS3 PTHR24418:SF369 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ZAP-70 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 T cell activation#P00053>ZAP-70#P01308 LEPOC|Ensembl=ENSLOCG00000007774.1|UniProtKB=W5MM31 W5MM31 INSYN2A PTHR28682:SF1 INHIBITORY SYNAPTIC FACTOR 2A-RELATED INHIBITORY SYNAPTIC FACTOR 2A signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of postsynaptic membrane potential#GO:0060078;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279 LEPOC|Ensembl=ENSLOCG00000017992.1|UniProtKB=W5NN84 W5NN84 PTHR15035:SF11 CORTICOLIBERIN/UROCORTIN UROCORTIN peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000003243.1|UniProtKB=W5M620 W5M620 PTHR12419:SF101 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010626.1|UniProtKB=W5MXA2 W5MXA2 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000002312.1|UniProtKB=W5M2V3 W5M2V3 PTHR46676:SF1 PROTEIN AMBP PROTEIN AMBP LEPOC|Ensembl=ENSLOCG00000012456.1|UniProtKB=W5N3X6 W5N3X6 PTHR22752:SF1 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 176 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005525.1|UniProtKB=W5ME59 W5ME59 PTHR11818:SF21 BETA/GAMMA CRYSTALLIN CRYSTALLIN, BETA B1, LIKE 3 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002780.1|UniProtKB=W5M4H0 W5M4H0 BCKDK PTHR11947:SF20 PYRUVATE DEHYDROGENASE KINASE [3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017308.1|UniProtKB=W5NLA4 W5NLA4 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008825.1|UniProtKB=W5MQS6 W5MQS6 PTHR11636:SF41 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002832.1|UniProtKB=W5M4P2 W5M4P2 PTHR11037:SF6 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 3 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009206.1|UniProtKB=W5MS75 W5MS75 PTHR22594:SF5 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006406.1|UniProtKB=W5MH75 W5MH75 PTHR10570:SF8 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;lymphocyte activation#GO:0046649;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;T cell differentiation#GO:0030217;cell activation#GO:0001775;regulation of biological process#GO:0050789;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;cell differentiation#GO:0030154;lymphocyte differentiation#GO:0030098;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;signaling#GO:0023052;leukocyte activation#GO:0045321 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 gamma#P01317 LEPOC|Ensembl=ENSLOCG00000007089.1|UniProtKB=W5MJM4 W5MJM4 PTHR22802:SF459 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN CONTAINING 19A membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016009.1|UniProtKB=W5NGG0 W5NGG0 FBXO48 PTHR12874:SF9 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 48 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007701.1|UniProtKB=W5MLU1 W5MLU1 PTHR40141:SF2 3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED 3',5'-CYCLIC-AMP PHOSPHODIESTERASE LEPOC|Ensembl=ENSLOCG00000014509.1|UniProtKB=W5NB47 W5NB47 PTHR45624:SF11 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1-LIKE L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000370.1|UniProtKB=W5LW96 W5LW96 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017423.1|UniProtKB=W5NLL9 W5NLL9 PTHR17149:SF3 NUCLEAR PROTEIN 1 AND 2 NUCLEAR PROTEIN 2 negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;negative regulation of cell cycle#GO:0045786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of cell population proliferation#GO:0008285;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012842.1|UniProtKB=W5N595 W5N595 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015485.1|UniProtKB=W5NEK0 W5NEK0 PTHR12497:SF0 TAZ PROTEIN TAFAZZIN TAFAZZIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009812.1|UniProtKB=W5MUD5 W5MUD5 PTHR11521:SF5 TROPONIN T TROPONIN T, CARDIAC MUSCLE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;circulatory system process#GO:0003013;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle contraction#GO:0006941;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000004810.1|UniProtKB=W5MBL5 W5MBL5 PTHR12313:SF13 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF185 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001317.1|UniProtKB=W5LZH0 W5LZH0 TERF2 PTHR46833:SF1 TELOMERIC REPEAT-BINDING FACTOR 2 TERF2 TELOMERIC REPEAT-BINDING FACTOR 2 LEPOC|Ensembl=ENSLOCG00000010423.1|UniProtKB=W5MWM4 W5MWM4 PTHR11377:SF14 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003455.1|UniProtKB=W5M6U4 W5M6U4 PTHR16320:SF8 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELIN PHOSPHODIESTERASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014210.1|UniProtKB=W5NA44 W5NA44 PTHR24390:SF227 ZINC FINGER PROTEIN KRUEPPEL HOMOLOG 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011066.1|UniProtKB=W5MYX8 W5MYX8 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016348.1|UniProtKB=W5NHT1 W5NHT1 PTHR11730:SF32 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE A inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006453.1|UniProtKB=W5MHD3 W5MHD3 PTHR14882:SF5 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN CONTAINING 74A LEPOC|Ensembl=ENSLOCG00000013268.1|UniProtKB=W5N6U2 W5N6U2 PTHR23320:SF143 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A-LIKE ISOFORM X1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006026.1|UniProtKB=W5MFX4 W5MFX4 PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008371.1|UniProtKB=W5MP58 W5MP58 PTHR14102:SF3 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG GAMMA establishment or maintenance of cell polarity#GO:0007163;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular anatomical structure#GO:0005622 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000015080.1|UniProtKB=W5ND52 W5ND52 PTHR12947:SF8 AMSH-LIKE PROTEASE STAM-BINDING PROTEIN hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein K63-linked deubiquitination#GO:0070536;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell division site#GO:0032153;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006113.1|UniProtKB=W5MG81 W5MG81 PTHR45638:SF16 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-1 monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;ligand-gated monoatomic cation channel activity#GO:0099094;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;tissue homeostasis#GO:0001894;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592;retina homeostasis#GO:0001895;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;anatomical structure homeostasis#GO:0060249;monoatomic cation transmembrane transport#GO:0098655 9+0 non-motile cilium#GO:0097731;membrane protein complex#GO:0098796;non-motile cilium#GO:0097730;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000004628.1|UniProtKB=W5MAY9 W5MAY9 PTHR18875:SF8 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO COILED-COIL DOMAIN-CONTAINING PROTEIN 18 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000014363.1|UniProtKB=W5NAM4 W5NAM4 PTHR46839:SF3 SUSHI DOMAIN-CONTAINING PROTEIN 6 SUSHI DOMAIN-CONTAINING PROTEIN 6 response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 LEPOC|Ensembl=ENSLOCG00000004572.1|UniProtKB=W5MAR2 W5MAR2 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000012098.1|UniProtKB=W5N2M8 W5N2M8 PTHR12191:SF2 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP8 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011422.1|UniProtKB=W5N078 W5N078 PTHR15603:SF1 SH3 DOMAIN-CONTAINING PROTEIN METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006557.1|UniProtKB=W5MHR3 W5MHR3 PTHR11732:SF402 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1-A oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003029.1|UniProtKB=W5M5B0 W5M5B0 PTHR14102:SF4 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG BETA establishment or maintenance of cell polarity#GO:0007163;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular anatomical structure#GO:0005622 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000015432.1|UniProtKB=W5NED1 W5NED1 PTHR34253:SF1 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA binding#GO:0003723;protein binding#GO:0005515;basal transcription machinery binding#GO:0001098;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;neurogenesis#GO:0022008;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;growth#GO:0040007;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;cell growth#GO:0016049;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell differentiation#GO:0030154;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015590.1|UniProtKB=W5NEY5 W5NEY5 PTHR12027:SF86 WNT RELATED PROTEIN WNT-2 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000000915.1|UniProtKB=W5LY15 W5LY15 PTHR45810:SF12 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009639.1|UniProtKB=W5MTS0 W5MTS0 PTHR11723:SF6 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-4 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013238.1|UniProtKB=W5N6P8 W5N6P8 PTHR11848:SF137 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 6 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000009922.1|UniProtKB=W5MUS1 W5MUS1 PTHR37984:SF15 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003669.1|UniProtKB=W5M7Q3 W5M7Q3 PTHR12844:SF21 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015373.1|UniProtKB=W5NE58 W5NE58 PTHR24034:SF102 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000007295.1|UniProtKB=W5MKC8 W5MKC8 PTHR19944:SF105 MHC CLASS II-RELATED RLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP ALPHA-1 CHAIN major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000005133.1|UniProtKB=W5MCR9 W5MCR9 PTHR13356:SF5 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B2 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;double-strand break repair#GO:0006302;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of mitotic cell cycle#GO:0045930;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000002387.1|UniProtKB=W5M354 W5M354 TNN PTHR19143:SF348 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-N cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;cell-substrate adhesion#GO:0031589;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell-matrix adhesion#GO:0007160;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004125.1|UniProtKB=W5M977 W5M977 PTHR11616:SF129 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;small molecule binding#GO:0036094;binding#GO:0005488;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation binding#GO:0043169;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic cyclic compound binding#GO:0097159;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;heterocyclic compound binding#GO:1901363;monoatomic anion transmembrane transporter activity#GO:0008509;ion binding#GO:0043167;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;neurotransmitter transport#GO:0006836;monoatomic cation transport#GO:0006812;establishment of localization in cell#GO:0051649;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016880.1|UniProtKB=W5NJR1 W5NJR1 PTHR10516:SF25 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007260.1|UniProtKB=W5MK74 W5MK74 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003867.1|UniProtKB=W5M8B4 W5M8B4 PTHR10281:SF1 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004403.1|UniProtKB=W5MA53 W5MA53 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002479.1|UniProtKB=W5M3E7 W5M3E7 PTHR11256:SF32 BCL-2 RELATED BCL2-LIKE 16 ISOFORM X1 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000014138.1|UniProtKB=W5N9W3 W5N9W3 PTHR11679:SF1 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000005008.1|UniProtKB=W5MCB9 W5MCB9 PTHR12002:SF177 CLAUDIN CLAUDIN-10-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000005053.1|UniProtKB=W5MCH3 W5MCH3 PTHR13084:SF5 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 4 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959 LEPOC|Ensembl=ENSLOCG00000002475.1|UniProtKB=W5M3F9 W5M3F9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008441.1|UniProtKB=W5MPF8 W5MPF8 GCA PTHR46735:SF5 CALPAIN, SMALL SUBUNIT 1 A-RELATED GRANCALCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000007392.1|UniProtKB=W5MKR1 W5MKR1 PTHR13105:SF4 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015178.1|UniProtKB=W5NDG8 W5NDG8 PMCH1 PTHR12091:SF0 MELANIN-CONCENTRATING HORMONE PRO-MCH protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 multicellular organismal process#GO:0032501;behavior#GO:0007610 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000006548.1|UniProtKB=W5MHQ2 W5MHQ2 PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015540.1|UniProtKB=W5NER9 W5NER9 PTHR11724:SF1 LEPTIN LEPTIN peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000014135.1|UniProtKB=W5N9V2 W5N9V2 PTHR47266:SF33 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012076.1|UniProtKB=W5N2L0 W5N2L0 PTHR46145:SF3 HEPARANASE HEPARANASE circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;cell adhesion#GO:0007155;wound healing#GO:0042060;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;anatomical structure formation involved in morphogenesis#GO:0048646;system development#GO:0048731;response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;cell-matrix adhesion#GO:0007160;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004882.1|UniProtKB=W5MBY1 W5MBY1 PTHR22635:SF0 RING FINGER PROTEIN 207 RING FINGER PROTEIN 207 protein binding#GO:0005515;heat shock protein binding#GO:0031072;transmembrane transporter binding#GO:0044325;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;positive regulation of molecular function#GO:0044093;regulation of localization#GO:0032879;positive regulation of transport#GO:0051050;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;positive regulation of transporter activity#GO:0032411;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014145.1|UniProtKB=W5N9W7 W5N9W7 PTHR47421:SF1 GS HOMEOBOX 2 GS HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003291.1|UniProtKB=W5M684 W5M684 PTHR12751:SF7 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000002185.1|UniProtKB=W5M2D8 W5M2D8 PTHR23039:SF6 NANCE-HORAN SYNDROME PROTEIN SIMILAR TO MKIAA1522 PROTEIN cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000012580.1|UniProtKB=W5N4C9 W5N4C9 GALNT11 PTHR11675:SF63 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cell communication#GO:0010646;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009808.1|UniProtKB=W5MUB9 W5MUB9 PTHR12392:SF0 LADININ 1 LADININ-1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002716.1|UniProtKB=W5M4A2 W5M4A2 PTHR10125:SF9 P2X PURINOCEPTOR P2X PURINOCEPTOR 1 monoatomic cation channel activity#GO:0005261;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017685.1|UniProtKB=W5NMD1 W5NMD1 PTHR40472:SF10 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 5 LEPOC|Ensembl=ENSLOCG00000006913.1|UniProtKB=W5MJ02 W5MJ02 PTHR15185:SF5 BCL9 B-CELL CLL_LYMPHOMA 9 PROTEIN protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>Bcl9#P01450 LEPOC|Ensembl=ENSLOCG00000010308.1|UniProtKB=W5MW72 W5MW72 PTHR21634:SF12 RE13835P FOLLICULIN-INTERACTING PROTEIN 1 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002943.1|UniProtKB=W5M519 W5M519 PTHR23101:SF98 RAB GDP/GTP EXCHANGE FACTOR VPS9 DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010445.1|UniProtKB=W5MWP1 W5MWP1 PTHR15710:SF243 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012037.1|UniProtKB=W5N2E6 W5N2E6 PTHR12429:SF10 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1B transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;protein localization to organelle#GO:0033365;import into cell#GO:0098657 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010169.1|UniProtKB=W5MVP0 W5MVP0 PTHR24031:SF25 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX46-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000007100.1|UniProtKB=W5MJN8 W5MJN8 PTHR10024:SF348 SYNAPTOTAGMIN SYNAPTOTAGMIN-17 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007631.1|UniProtKB=W5MLJ6 W5MLJ6 PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011682.1|UniProtKB=W5N147 W5N147 PTHR24416:SF279 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;phagocytosis#GO:0006909;endocytosis#GO:0006897;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;import into cell#GO:0098657;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005521.1|UniProtKB=W5ME55 W5ME55 PTHR24248:SF140 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE RECEPTOR H3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012532.1|UniProtKB=W5N474 W5N474 PTHR19143:SF422 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000006585.1|UniProtKB=W5MHU6 W5MHU6 ARNT PTHR23042:SF50 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Hypoxia response via HIF activation#P00030>HIF-1beta#P00820 LEPOC|Ensembl=ENSLOCG00000016713.1|UniProtKB=W5NJ41 W5NJ41 PTHR46380:SF2 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009194.1|UniProtKB=W5MS60 W5MS60 PTHR24020:SF15 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIV) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000005519.1|UniProtKB=W5ME65 W5ME65 PTHR22753:SF14 TRANSMEMBRANE PROTEIN 68 MONOACYLGLYCEROL_DIACYLGLYCEROL O-ACYLTRANSFERASE cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016740.1|UniProtKB=W5NJ82 W5NJ82 DNPH1 PTHR15364:SF0 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;nucleoside monophosphate metabolic process#GO:0009123;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011840.1|UniProtKB=W5N1P9 W5N1P9 PTHR32261:SF3 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 2 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000009308.1|UniProtKB=W5MSJ3 W5MSJ3 PTHR24243:SF3 G-PROTEIN COUPLED RECEPTOR MOTILIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014081.1|UniProtKB=W5N9R1 W5N9R1 PTHR13280:SF15 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 2 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 LEPOC|Ensembl=ENSLOCG00000003498.1|UniProtKB=W5M6Z0 W5M6Z0 PTHR47977:SF33 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 positive regulation of secretion#GO:0051047;transport#GO:0006810;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;export from cell#GO:0140352;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010983.1|UniProtKB=W5MYL1 W5MYL1 PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006353.1|UniProtKB=W5MH09 W5MH09 PTHR11461:SF20 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-2-ANTIPLASMIN peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>alpha2-antiplasmin#P00428;Plasminogen activating cascade#P00050>alpha2 antiplasmin#P01264 LEPOC|Ensembl=ENSLOCG00000013104.1|UniProtKB=W5N682 W5N682 PTHR35539:SF1 CDNA SEQUENCE BC048562 CDNA SEQUENCE BC048562 LEPOC|Ensembl=ENSLOCG00000003590.1|UniProtKB=W5M7C7 W5M7C7 PTHR15735:SF13 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000016693.1|UniProtKB=W5NJ14 W5NJ14 PTHR11537:SF274 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;calmodulin binding#GO:0005516;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000010399.1|UniProtKB=W5MWJ4 W5MWJ4 PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017966.1|UniProtKB=W5NN60 W5NN60 PTHR14790:SF15 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;response to stress#GO:0006950;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000002542.1|UniProtKB=W5M3R8 W5M3R8 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010222.1|UniProtKB=W5MVW0 W5MVW0 PTHR10257:SF92 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000015230.1|UniProtKB=W5NDN5 W5NDN5 PTHR10372:SF25 PLAKOPHILLIN-RELATED PLAKOPHILIN-2 protein localization to plasma membrane#GO:0072659;cellular component assembly#GO:0022607;localization within membrane#GO:0051668;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;heart development#GO:0007507;circulatory system development#GO:0072359;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intercalated disc#GO:0014704;membrane-bounded organelle#GO:0043227;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000001937.1|UniProtKB=W5M1M2 W5M1M2 PTHR23280:SF15 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 5 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000013258.1|UniProtKB=W5N6S1 W5N6S1 PTHR15907:SF30 DUF614 FAMILY PROTEIN-RELATED CORNIFELIN HOMOLOG B-RELATED LEPOC|Ensembl=ENSLOCG00000010724.1|UniProtKB=W5MXN8 W5MXN8 PTHR13116:SF10 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000012010.1|UniProtKB=W5N2C9 W5N2C9 PTHR45615:SF16 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-9 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000009070.1|UniProtKB=W5MRP1 W5MRP1 CNNM1 PTHR12064:SF28 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004208.1|UniProtKB=W5M9H2 W5M9H2 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017061.1|UniProtKB=W5NKC6 W5NKC6 PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of sister chromatid segregation#GO:0033046;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of mitotic sister chromatid segregation#GO:0033047;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;cellular macromolecule localization#GO:0070727;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;negative regulation of cell cycle process#GO:0010948;peptidyl-serine phosphorylation#GO:0018105;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of mitotic cell cycle phase transition#GO:1901991;protein localization to kinetochore#GO:0034501;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;protein localization to organelle#GO:0033365;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;negative regulation of mitotic cell cycle#GO:0045930;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;regulation of meiotic cell cycle#GO:0051445;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;peptidyl-serine modification#GO:0018209;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004146.1|UniProtKB=W5M9A8 W5M9A8 PTHR24006:SF647 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000854.1|UniProtKB=W5LXU1 W5LXU1 PTHR13452:SF10 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000002577.1|UniProtKB=W5M3S1 W5M3S1 PTHR16019:SF5 SYNAPSE-ASSOCIATED PROTEIN BSD DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018017.1|UniProtKB=W5NNA9 W5NNA9 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010043.1|UniProtKB=W5MV78 W5MV78 PTHR12447:SF25 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016140.1|UniProtKB=W5NGY4 W5NGY4 PTHR46298:SF1 ANDROGLOBIN ANDROGLOBIN LEPOC|Ensembl=ENSLOCG00000017749.1|UniProtKB=W5NMJ4 W5NMJ4 PTHR24230:SF53 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001293.1|UniProtKB=W5LZB7 W5LZB7 HCRTR1 PTHR24241:SF30 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN_HYPOCRETIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016620.1|UniProtKB=W5NIS1 W5NIS1 PTHR11328:SF30 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SPHINGOSINE-1-PHOSPHATE TRANSPORTER MFSD2B transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid transport#GO:0006869;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012352.1|UniProtKB=W5N3K5 W5N3K5 PTHR45888:SF10 HL01030P-RELATED ZINC FINGER PROTEIN DPF3 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005517.1|UniProtKB=W5ME56 W5ME56 PTHR13020:SF28 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6A PROTEIN negative regulation of gene expression#GO:0010629;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006648.1|UniProtKB=W5MI32 W5MI32 PTHR12093:SF11 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1 cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699;cell migration#GO:0016477;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008186.1|UniProtKB=W5MNH9 W5MNH9 PTHR23320:SF129 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 15 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003862.1|UniProtKB=W5M8G1 W5M8G1 PTHR23317:SF71 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 10 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;developmental process#GO:0032502;dendrite development#GO:0016358;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;neuron differentiation#GO:0030182;regulation of hydrolase activity#GO:0051336;plasma membrane bounded cell projection morphogenesis#GO:0120039;postsynapse organization#GO:0099173;cellular developmental process#GO:0048869;regulation of cell motility#GO:2000145;regulation of GTPase activity#GO:0043087;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;dendrite morphogenesis#GO:0048813;dendritic spine morphogenesis#GO:0060997;positive regulation of hydrolase activity#GO:0051345;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000005984.1|UniProtKB=W5MFS5 W5MFS5 PTHR47236:SF5 GENE, 32742-RELATED-RELATED GENE, 32742-RELATED LEPOC|Ensembl=ENSLOCG00000013105.1|UniProtKB=W5N684 W5N684 PTHR12271:SF127 POLY A POLYMERASE CID PAP -RELATED SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000000458.1|UniProtKB=W5LWJ9 W5LWJ9 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 1 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015466.1|UniProtKB=W5NEI2 W5NEI2 PTHR11736:SF14 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011128.1|UniProtKB=W5MZ76 W5MZ76 PTHR45626:SF50 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 LEPOC|Ensembl=ENSLOCG00000011425.1|UniProtKB=W5N097 W5N097 PTHR22692:SF16 MYOSIN VII, XV MYOSIN XVB actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000006959.1|UniProtKB=W5MJ68 W5MJ68 AP2A2 PTHR22780:SF30 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;plasma membrane protein complex#GO:0098797;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 LEPOC|Ensembl=ENSLOCG00000015656.1|UniProtKB=W5NF62 W5NF62 PROSC PTHR10146:SF14 PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011266.1|UniProtKB=W5MZM9 W5MZM9 PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009642.1|UniProtKB=W5MTS5 W5MTS5 PTHR13798:SF11 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA-BINDING PROTEIN 7-RELATED RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000518.1|UniProtKB=W5LWR3 W5LWR3 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011271.1|UniProtKB=W5MZP3 W5MZP3 PTHR11085:SF9 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>SIRT-1#P04632 LEPOC|Ensembl=ENSLOCG00000015270.1|UniProtKB=W5NDT1 W5NDT1 PTHR48069:SF5 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;carboxylic acid metabolic process#GO:0019752;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005440.1|UniProtKB=W5MDU4 W5MDU4 C1orf52 PTHR31833:SF2 UPF0690 PROTEIN C1ORF52 UPF0690 PROTEIN C1ORF52 LEPOC|Ensembl=ENSLOCG00000005606.1|UniProtKB=W5MEH5 W5MEH5 PTHR45754:SF3 METHYLENETETRAHYDROFOLATE REDUCTASE METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH) nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013359.1|UniProtKB=W5N760 W5N760 CXCL8 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A PLATELET BASIC PROTEIN cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005693.1|UniProtKB=W5MER9 W5MER9 ANKMY1 PTHR15897:SF2 ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006206.1|UniProtKB=W5MGI8 W5MGI8 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000000448.1|UniProtKB=W5LWL9 W5LWL9 PTHR22796:SF6 URG4-RELATED INTERFERON-INDUCED VERY LARGE GTPASE 1-RELATED LEPOC|Ensembl=ENSLOCG00000004874.1|UniProtKB=W5MBU7 W5MBU7 PTHR14387:SF0 THADA/DEATH RECEPTOR INTERACTING PROTEIN DUF2428 DOMAIN-CONTAINING PROTEIN cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017316.1|UniProtKB=W5NLB2 W5NLB2 PTHR24369:SF8 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of axonogenesis#GO:0050770;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005272.1|UniProtKB=W5MD96 W5MD96 PTHR13723:SF167 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006339.1|UniProtKB=W5MH07 W5MH07 PTHR45858:SF4 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 LEPOC|Ensembl=ENSLOCG00000012182.1|UniProtKB=W5N2X0 W5N2X0 PTHR11814:SF16 SULFATE TRANSPORTER SULFATE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009415.1|UniProtKB=W5MSY6 W5MSY6 PTHR11141:SF7 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23A nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009518.1|UniProtKB=W5MTC0 W5MTC0 PTHR21357:SF5 FAM172 FAMILY PROTEIN HOMOLOG CG10038 SI:CH73-41E3.7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008004.1|UniProtKB=W5MMW1 W5MMW1 PTHR11639:SF131 S100 CALCIUM-BINDING PROTEIN PROTEIN S100 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017507.1|UniProtKB=W5NLV3 W5NLV3 PTHR19290:SF168 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012683.1|UniProtKB=W5N4Q4 W5N4Q4 AFMID PTHR23024:SF574 ARYLACETAMIDE DEACETYLASE KYNURENINE FORMAMIDASE deacetylase#PC00087;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011934.1|UniProtKB=W5N217 W5N217 PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;cation channel complex#GO:0034703;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000002838.1|UniProtKB=W5M4N2 W5M4N2 PTHR46485:SF6 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002985.1|UniProtKB=W5M557 W5M557 PTHR15326:SF7 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2-LIKE PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005227.1|UniProtKB=W5MD59 W5MD59 PTHR13084:SF4 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959 LEPOC|Ensembl=ENSLOCG00000006533.1|UniProtKB=W5MHN5 W5MHN5 PTHR12358:SF26 SPHINGOSINE KINASE CERAMIDE KINASE-LIKE PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000006195.1|UniProtKB=W5MGH4 W5MGH4 PTHR45644:SF2 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED OUTER MITOCHONDRIAL TRANSMEMBRANE HELIX TRANSLOCASE localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein localization to membrane#GO:0072657;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000013311.1|UniProtKB=W5N707 W5N707 PTHR21229:SF81 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87A localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005997.1|UniProtKB=W5MFU6 W5MFU6 PTHR11785:SF398 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 2 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011006.1|UniProtKB=W5MYQ2 W5MYQ2 PTHR21501:SF4 PROTEIN FAM-161 PROTEIN FAM161B cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006058.1|UniProtKB=W5MG05 W5MG05 PTHR14471:SF1 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF7 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003982.1|UniProtKB=W5M8Q7 W5M8Q7 PTHR24061:SF435 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;sensory perception of taste#GO:0050909;system process#GO:0003008 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011172.1|UniProtKB=W5MZB7 W5MZB7 PTHR16356:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000014846.1|UniProtKB=W5NCC2 W5NCC2 PTHR21347:SF14 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000012486.1|UniProtKB=W5N410 W5N410 PTHR24342:SF16 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE KINASE 17A-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006768.1|UniProtKB=W5MIH0 W5MIH0 PTHR13869:SF14 MYELIN P0 RELATED SODIUM CHANNEL SUBUNIT BETA-4 protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;channel regulator activity#GO:0016247;binding#GO:0005488;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;blood circulation#GO:0008015;regulation of sodium ion transport#GO:0002028;actin filament-based movement#GO:0030048;regulation of metal ion transport#GO:0010959;system process#GO:0003008;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;heart process#GO:0003015;muscle contraction#GO:0006936 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004663.1|UniProtKB=W5MB23 W5MB23 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 SMALL RIBOSOMAL SUBUNIT PROTEIN MS23 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001817.1|UniProtKB=W5M142 W5M142 PTHR11042:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE_THREONINE-PROTEIN KINASE 35 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;negative regulation of cell cycle process#GO:0010948;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008435.1|UniProtKB=W5MPE8 W5MPE8 USP42 PTHR24006:SF727 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 42 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001007.1|UniProtKB=W5LYC7 W5LYC7 PTHR23277:SF11 NECTIN-RELATED NECTIN-4 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008247.1|UniProtKB=W5MNP8 W5MNP8 TDO2 PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;dioxygenase activity#GO:0051213;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008997.1|UniProtKB=W5MRF5 W5MRF5 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;double-stranded DNA binding#GO:0003690;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000105.1|UniProtKB=W5LVH2 W5LVH2 PTHR10694:SF7 LYSINE-SPECIFIC DEMETHYLASE [HISTONE H3]-TRIMETHYL-L-LYSINE(9) DEMETHYLASE histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000003841.1|UniProtKB=W5M881 W5M881 PTHR15352:SF2 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cGMP-mediated signaling#GO:0019934;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001472.1|UniProtKB=W5LZY4 W5LZY4 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4-LIKE ISOFORM X1 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000005453.1|UniProtKB=W5MDX1 W5MDX1 PTHR23065:SF18 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002093.1|UniProtKB=W5M230 W5M230 PTHR21677:SF1 CRAMPED PROTEIN PROTEIN CRAMPED-LIKE protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007099.1|UniProtKB=W5MJP8 W5MJP8 PTHR11639:SF115 S100 CALCIUM-BINDING PROTEIN S100 CALCIUM-BINDING PROTEIN U-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000004646.1|UniProtKB=W5MB09 W5MB09 PTHR15829:SF2 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 2 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010529.1|UniProtKB=W5MWY8 W5MWY8 PTHR44068:SF1 ZGC:194242 HYPOTHETICAL LOC100005854 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004593.1|UniProtKB=W5MAU0 W5MAU0 PTHR46708:SF10 TENASCIN RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA-LIKE extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000004851.1|UniProtKB=W5MBR9 W5MBR9 PTHR10073:SF12 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003994.1|UniProtKB=W5M8Q8 W5M8Q8 PTHR45817:SF10 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000332.1|UniProtKB=W5LW53 W5LW53 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000018086.1|UniProtKB=W5NNH8 W5NNH8 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000000267.1|UniProtKB=W5LVZ4 W5LVZ4 PTHR10459:SF60 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000004388.1|UniProtKB=W5MA34 W5MA34 PTHR11545:SF3 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006583.1|UniProtKB=W5MHU5 W5MHU5 PTHR10856:SF23 CORONIN CORONIN-6 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007211.1|UniProtKB=W5MK15 W5MK15 PTHR10031:SF59 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C3, MITOCHONDRIAL cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000758.1|UniProtKB=W5LXI3 W5LXI3 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE INACTIVE ADP-RIBOSYLTRANSFERASE ARH2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009671.1|UniProtKB=W5MTV7 W5MTV7 PTHR18860:SF154 14-3-3 PROTEIN TYROSINE 3-MONOOXYGENASE_TRYPTOPHAN 5-MONOOXYGENASE ACTIVATION PROTEIN, BETA POLYPEPTIDE LIKE ISOFORM X1-RELATED localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017830.1|UniProtKB=W5NMS4 W5NMS4 PTHR20889:SF1 PHOSPHATASE, ORPHAN 1, 2 PYRIDOXAL PHOSPHATE PHOSPHATASE PHOSPHO2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004972.1|UniProtKB=W5MC96 W5MC96 PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010695.1|UniProtKB=W5MXJ5 W5MXJ5 PTHR23510:SF3 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000018135.1|UniProtKB=W5NNM7 W5NNM7 PTHR10903:SF168 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001357.1|UniProtKB=W5LZI0 W5LZI0 PTHR22930:SF236 FAMILY NOT NAMED PROTEIN ALP1-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000008638.1|UniProtKB=W5MQ38 W5MQ38 PTHR16655:SF3 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT CH11 LEPOC|Ensembl=ENSLOCG00000014724.1|UniProtKB=W5NBX1 W5NBX1 PTHR12027:SF34 WNT RELATED PROTEIN WNT molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000007652.1|UniProtKB=W5MLM1 W5MLM1 PTHR13780:SF38 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000014153.1|UniProtKB=W5N9X5 W5N9X5 PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of biological quality#GO:0065008;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;negative regulation of cellular process#GO:0048523;negative regulation of apoptotic process#GO:0043066;protein stabilization#GO:0050821;regulation of programmed cell death#GO:0043067 LEPOC|Ensembl=ENSLOCG00000012813.1|UniProtKB=W5N559 W5N559 PTHR46171:SF1 GH10160P E3 UBIQUITIN-PROTEIN LIGASE RNF38 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000016210.1|UniProtKB=W5NH73 W5NH73 PTHR28592:SF2 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000013370.1|UniProtKB=W5N773 W5N773 PTHR15572:SF4 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 PROTEIN-LIKE ISOFORM X1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000001797.1|UniProtKB=W5M125 W5M125 PTHR12888:SF0 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005022.1|UniProtKB=W5MCE2 W5MCE2 PTHR19229:SF113 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 13 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001340.1|UniProtKB=W5LZG2 W5LZG2 PTHR15545:SF6 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 PDZ DOMAIN-CONTAINING RING FINGER PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000013376.1|UniProtKB=W5N778 W5N778 PTHR13620:SF104 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017773.1|UniProtKB=W5NML8 W5NML8 PTHR24237:SF38 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013313.1|UniProtKB=W5N700 W5N700 PTHR10877:SF145 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005011.1|UniProtKB=W5MCE3 W5MCE3 PTHR46489:SF2 STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL START DOMAIN-CONTAINING PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;intracellular sterol transport#GO:0032366;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;intracellular cholesterol transport#GO:0032367;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of lipid metabolic process#GO:0019216;intracellular transport#GO:0046907;lipid localization#GO:0010876;regulation of lipid biosynthetic process#GO:0046890;regulation of metabolic process#GO:0019222;intracellular lipid transport#GO:0032365 LEPOC|Ensembl=ENSLOCG00000009861.1|UniProtKB=W5MUJ3 W5MUJ3 PTHR13580:SF10 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009381.1|UniProtKB=W5MST7 W5MST7 PTHR48408:SF1 FAMILY NOT NAMED XYLOSE ISOMERASE LEPOC|Ensembl=ENSLOCG00000005649.1|UniProtKB=W5MEL5 W5MEL5 PLK1 PTHR24345:SF93 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002560.1|UniProtKB=W5M3P9 W5M3P9 PTHR13968:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1_C2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014178.1|UniProtKB=W5NA07 W5NA07 PTHR14211:SF7 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010070.1|UniProtKB=W5MVB2 W5MVB2 PTHR47992:SF121 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004661.1|UniProtKB=W5MB17 W5MB17 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007010.1|UniProtKB=W5MJC9 W5MJC9 PTHR45704:SF7 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11B LEPOC|Ensembl=ENSLOCG00000002004.1|UniProtKB=W5M1Q9 W5M1Q9 PTHR45652:SF4 GLIAL FIBRILLARY ACIDIC PROTEIN INTERMEDIATE FILAMENT PROTEIN-LIKE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;synapse#GO:0045202;intermediate filament#GO:0005882;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;postsynapse#GO:0098794;cytoskeleton#GO:0005856;cell projection#GO:0042995 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000017841.1|UniProtKB=W5NMT5 W5NMT5 PTHR24366:SF159 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS CD180 MOLECULE cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015596.1|UniProtKB=W5NEZ4 W5NEZ4 PTHR24064:SF33 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 7 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001359.1|UniProtKB=W5LZJ1 W5LZJ1 PTHR23423:SF59 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184A localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012728.1|UniProtKB=W5N4V4 W5N4V4 PTHR19282:SF63 TETRASPANIN TETRASPANIN-5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005683.1|UniProtKB=W5MEQ5 W5MEQ5 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002745.1|UniProtKB=W5M4C5 W5M4C5 PTHR24343:SF569 SERINE/THREONINE KINASE CALCIUM_CALMODULIN DEPENDENT PROTEIN KINASE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001507.1|UniProtKB=W5M095 W5M095 ADAMTS20 PTHR13723:SF165 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 20 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010828.1|UniProtKB=W5MY09 W5MY09 PTHR44668:SF2 FAMILY NOT NAMED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7C LEPOC|Ensembl=ENSLOCG00000005261.1|UniProtKB=W5MD78 W5MD78 PTHR24390:SF94 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR E4F1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011208.1|UniProtKB=W5MZH1 W5MZH1 PTHR45688:SF1 FAMILY NOT NAMED ETHANOLAMINE-PHOSPHATE PHOSPHO-LYASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005350.1|UniProtKB=W5MDK8 W5MDK8 PTHR24085:SF2 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005903.1|UniProtKB=W5MFH9 W5MFH9 PTHR15463:SF2 AP1 GAMMA SUBUNIT BINDING PROTEIN 1 SYNERGIN GAMMA bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;Golgi-associated vesicle membrane#GO:0030660;clathrin-coated vesicle#GO:0030136;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140 LEPOC|Ensembl=ENSLOCG00000013275.1|UniProtKB=W5N6V1 W5N6V1 PTHR31626:SF3 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A2 LEPOC|Ensembl=ENSLOCG00000013405.1|UniProtKB=W5N7B8 W5N7B8 PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization within membrane#GO:0051668;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;post-translational protein targeting to membrane, translocation#GO:0031204;protein localization to membrane#GO:0072657;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017478.1|UniProtKB=W5NLS4 W5NLS4 PTHR33064:SF37 POL PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000012501.1|UniProtKB=W5N431 W5N431 PTHR10513:SF48 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000017873.1|UniProtKB=W5NMW7 W5NMW7 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 53 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000000793.1|UniProtKB=W5LXM2 W5LXM2 PTHR31193:SF1 TRANSMEMBRANE PROTEIN C9ORF91 TRANSMEMBRANE PROTEIN 268 LEPOC|Ensembl=ENSLOCG00000017479.1|UniProtKB=W5NLS5 W5NLS5 PTHR10614:SF2 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 4 protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 LEPOC|Ensembl=ENSLOCG00000015593.1|UniProtKB=W5NEY9 W5NEY9 PTHR10653:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000014262.1|UniProtKB=W5NAA1 W5NAA1 PTHR31553:SF3 NF-KAPPA-B ESSENTIAL MODULATOR NF-KAPPA-B ESSENTIAL MODULATOR protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006295.1|UniProtKB=W5MGU3 W5MGU3 PTHR45804:SF5 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-C13 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012773.1|UniProtKB=W5N509 W5N509 UGT3A2 PTHR48043:SF24 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 3A2 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000001903.1|UniProtKB=W5M1F4 W5M1F4 PTHR32123:SF11 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 2-RELATED vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000009919.1|UniProtKB=W5MUS0 W5MUS0 PTHR11492:SF6 NUCLEAR FACTOR I NUCLEAR FACTOR 1 A-TYPE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007953.1|UniProtKB=W5MMR3 W5MMR3 PTHR45742:SF2 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C7 activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000003109.1|UniProtKB=W5M5K6 W5M5K6 PTHR24103:SF688 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014939.1|UniProtKB=W5NCN5 W5NCN5 PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 LEPOC|Ensembl=ENSLOCG00000008808.1|UniProtKB=W5MQS0 W5MQS0 PTHR13723:SF140 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 16 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013847.1|UniProtKB=W5N8W9 W5N8W9 PTHR46389:SF1 POLYCOMB GROUP PROTEIN PC CHROMOBOX PROTEIN HOMOLOG 8 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000553.1|UniProtKB=W5LWV3 W5LWV3 CCDC39 PTHR18962:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000002924.1|UniProtKB=W5M4X9 W5M4X9 PTHR10993:SF12 OCTANOYLTRANSFERASE OCTANOYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017488.1|UniProtKB=W5NLT4 W5NLT4 PTHR24232:SF41 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010703.1|UniProtKB=W5MXL7 W5MXL7 PTHR13743:SF115 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005949.1|UniProtKB=W5MFM8 W5MFM8 PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018331.1|UniProtKB=W5NP73 W5NP73 PTHR14581:SF4 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000002748.1|UniProtKB=W5M4F2 W5M4F2 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER C2 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009913.1|UniProtKB=W5MUQ5 W5MUQ5 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016535.1|UniProtKB=W5NIG2 W5NIG2 PTHR12101:SF18 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;muscle organ development#GO:0007517;heart development#GO:0007507;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;skeletal muscle tissue development#GO:0007519 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008261.1|UniProtKB=W5MNS2 W5MNS2 PTHR22957:SF215 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10A nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000006501.1|UniProtKB=W5MHJ5 W5MHJ5 PTHR22957:SF337 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 5 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000018081.1|UniProtKB=W5NNH3 W5NNH3 PTHR24237:SF37 G-PROTEIN COUPLED RECEPTOR COAGULATION FACTOR II (THROMBIN) RECEPTOR-LIKE 2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018317.1|UniProtKB=W5NP59 W5NP59 PTHR12611:SF2 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017973.1|UniProtKB=W5NN65 W5NN65 PTHR10489:SF635 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 7 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000010420.1|UniProtKB=W5MWL8 W5MWL8 PTHR11636:SF43 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003872.1|UniProtKB=W5M8B7 W5M8B7 PTHR18945:SF196 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017844.1|UniProtKB=W5NMT8 W5NMT8 PTHR46648:SF1 HIT FAMILY PROTEIN 1 ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1 LEPOC|Ensembl=ENSLOCG00000014177.1|UniProtKB=W5NA14 W5NA14 PTHR24416:SF625 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;positive regulation of cellular metabolic process#GO:0031325;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of angiogenesis#GO:0045765;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell motility#GO:0048870;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011399.1|UniProtKB=W5N055 W5N055 POLR1F PTHR12709:SF5 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;rRNA transcription#GO:0009303;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;transcription elongation by RNA polymerase I#GO:0006362;heterocycle metabolic process#GO:0046483;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000010446.1|UniProtKB=W5MWR5 W5MWR5 PTHR24355:SF14 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 LEPOC|Ensembl=ENSLOCG00000005250.1|UniProtKB=W5MD64 W5MD64 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008220.1|UniProtKB=W5MNM3 W5MNM3 PTHR13388:SF29 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000012309.1|UniProtKB=W5N3E3 W5N3E3 PTHR12106:SF44 SORTILIN RELATED SORTILIN 1B Golgi to endosome transport#GO:0006895;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006663.1|UniProtKB=W5MI36 W5MI36 PTHR15348:SF2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3C nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014105.1|UniProtKB=W5N9S1 W5N9S1 PTHR15913:SF0 ACID CLUSTER PROTEIN 33 MASPARDIN LEPOC|Ensembl=ENSLOCG00000009362.1|UniProtKB=W5MSR1 W5MSR1 PTHR22647:SF2 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of ERBB signaling pathway#GO:1901184;regulation of cellular localization#GO:0060341;regulation of protein transport#GO:0051223;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001273.1|UniProtKB=W5LZ88 W5LZ88 PTHR23176:SF108 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 15 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000001936.1|UniProtKB=W5M1K4 W5M1K4 PTHR43778:SF2 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;glucose metabolic process#GO:0006006;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 LEPOC|Ensembl=ENSLOCG00000016325.1|UniProtKB=W5NHP3 W5NHP3 PTHR24329:SF547 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN PROPHET OF PIT-1-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010581.1|UniProtKB=W5MX55 W5MX55 PTHR11849:SF10 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000017982.1|UniProtKB=W5NN74 W5NN74 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000012704.1|UniProtKB=W5N4U2 W5N4U2 PTHR21704:SF18 NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED NIPPED-B-LIKE PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular localization#GO:0051641;double-strand break repair#GO:0006302;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;establishment of protein localization#GO:0045184;sister chromatid cohesion#GO:0007062;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;protein localization to organelle#GO:0033365;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic sister chromatid cohesion#GO:0007064;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;protein localization#GO:0008104;primary metabolic process#GO:0044238;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010076.1|UniProtKB=W5MVB8 W5MVB8 PTHR23185:SF0 PROTEIN VIRILIZER HOMOLOG PROTEIN VIRILIZER HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;mRNA modification#GO:0016556;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000017182.1|UniProtKB=W5NKS8 W5NKS8 PTHR12933:SF0 ORF PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016511.1|UniProtKB=W5NID6 W5NID6 ECHDC1 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydratase#PC00120 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 LEPOC|Ensembl=ENSLOCG00000006285.1|UniProtKB=W5MGT1 W5MGT1 PTHR13097:SF7 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEalpha#P00669;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398 LEPOC|Ensembl=ENSLOCG00000014360.1|UniProtKB=W5NAM3 W5NAM3 PTHR24241:SF69 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE II RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000003721.1|UniProtKB=W5M7R3 W5M7R3 IL12A PTHR48485:SF1 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT ALPHA Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 LEPOC|Ensembl=ENSLOCG00000001043.1|UniProtKB=W5LYG3 W5LYG3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015842.1|UniProtKB=W5NFU3 W5NFU3 ATXN7L1 PTHR15117:SF9 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017282.1|UniProtKB=W5NL69 W5NL69 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER LEPOC|Ensembl=ENSLOCG00000009918.1|UniProtKB=W5MUS5 W5MUS5 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013300.1|UniProtKB=W5N6Y3 W5N6Y3 PTHR24198:SF176 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND SOCS BOX CONTAINING 14 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009560.1|UniProtKB=W5MTH9 W5MTH9 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA negative regulation of biological process#GO:0048519;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of organelle assembly#GO:1902115;negative regulation of organelle organization#GO:0010639;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000015730.1|UniProtKB=W5NFF4 W5NFF4 PTHR11849:SF172 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>ELK#P00962 LEPOC|Ensembl=ENSLOCG00000014836.1|UniProtKB=W5NCB4 W5NCB4 PTHR14388:SF6 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 7 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008550.1|UniProtKB=W5MPU7 W5MPU7 PTHR24291:SF201 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007244.1|UniProtKB=W5MK55 W5MK55 PTHR24369:SF213 ANTIGEN BSP, PUTATIVE-RELATED INSULIN LIKE GROWTH FACTOR BINDING PROTEIN ACID LABILE SUBUNIT cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006345.1|UniProtKB=W5MH04 W5MH04 PTHR10165:SF25 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008974.1|UniProtKB=W5MRC6 W5MRC6 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 amylase#PC00048;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003339.1|UniProtKB=W5M6D7 W5M6D7 MANEAL PTHR13572:SF2 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000006397.1|UniProtKB=W5MH83 W5MH83 PTHR23273:SF172 REPLICATION FACTOR A 1, RFA1 REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded telomeric DNA binding#GO:0043047;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;telomeric DNA binding#GO:0042162 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;telomere maintenance via telomere lengthening#GO:0010833;double-strand break repair#GO:0006302;telomere organization#GO:0032200;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;reproductive process#GO:0022414;telomere maintenance via telomerase#GO:0007004;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;sexual reproduction#GO:0019953;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear replication fork#GO:0043596;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006223.1|UniProtKB=W5MGK5 W5MGK5 PTHR24082:SF112 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014771.1|UniProtKB=W5NC29 W5NC29 PTHR46030:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012997.1|UniProtKB=W5N5V2 W5N5V2 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000012180.1|UniProtKB=W5N2Z9 W5N2Z9 PTHR14166:SF6 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of locomotion#GO:0040013;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000011224.1|UniProtKB=W5MZI2 W5MZI2 PTHR11977:SF78 VILLIN SCINDERIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;cellular component biogenesis#GO:0044085;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;central nervous system development#GO:0007417;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;cell projection assembly#GO:0030031;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000014642.1|UniProtKB=W5NBL1 W5NBL1 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000012133.1|UniProtKB=W5N2S0 W5N2S0 PTHR23063:SF10 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000020975.1|UniProtKB=Q8HQN2 Q8HQN2 ND2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013131.1|UniProtKB=W5N6C0 W5N6C0 PTHR19960:SF11 TEKTIN TEKTIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000017470.1|UniProtKB=W5NLR6 W5NLR6 PTHR13947:SF60 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000002413.1|UniProtKB=W5M374 W5M374 PTHR24230:SF78 G-PROTEIN COUPLED RECEPTOR KISS-1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012398.1|UniProtKB=W5N3Q7 W5N3Q7 PTHR13501:SF8 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006716.1|UniProtKB=W5MIA2 W5MIA2 PTHR10395:SF12 URICASE AND TRANSTHYRETIN-RELATED TRANSTHYRETIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005590.1|UniProtKB=W5MEE8 W5MEE8 SETD2 PTHR46711:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000003432.1|UniProtKB=W5M6Q8 W5M6Q8 WDR49 PTHR44324:SF1 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 49 LEPOC|Ensembl=ENSLOCG00000006091.1|UniProtKB=W5MG49 W5MG49 PTHR10707:SF13 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006531.1|UniProtKB=W5MHN4 W5MHN4 PTHR21705:SF4 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1B lysosome organization#GO:0007040;endosomal transport#GO:0016197;cellular localization#GO:0051641;vacuolar transport#GO:0007034;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vacuole organization#GO:0007033;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;early endosome to late endosome transport#GO:0045022 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008721.1|UniProtKB=W5MQJ6 W5MQJ6 PTHR12552:SF5 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 10 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>GRAF#P00926;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000018185.1|UniProtKB=W5NNS7 W5NNS7 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017755.1|UniProtKB=W5NMK0 W5NMK0 PTHR24229:SF6 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;response to estradiol#GO:0032355;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to steroid hormone#GO:0048545 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000002313.1|UniProtKB=W5M2W2 W5M2W2 PCSK4 PTHR42884:SF3 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 1, ISOFORMS 1_1-X_2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Activin beta signaling pathway#P06210>FUR1#P06238;Endothelin signaling pathway#P00019>furin#P00575;GBB signaling pathway#P06214>FUR1#P06298;SCW signaling pathway#P06216>FUR1#P06333;DPP-SCW signaling pathway#P06212>FUR1#P06263;DPP signaling pathway#P06213>FUR1#P06290;ALP23B signaling pathway#P06209>FUR1#P06227;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;BMP/activin signaling pathway-drosophila#P06211>Furin#P06244;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;MYO signaling pathway#P06215>FUR1#P06318 LEPOC|Ensembl=ENSLOCG00000017889.1|UniProtKB=W5NMY3 W5NMY3 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002675.1|UniProtKB=W5M430 W5M430 PTHR22750:SF22 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;system development#GO:0048731;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002391.1|UniProtKB=W5M368 W5M368 PTHR24257:SF19 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003363.1|UniProtKB=W5M6G8 W5M6G8 PTHR11042:SF58 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE_THREONINE-PROTEIN KINASE PDIK1L transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;negative regulation of cell cycle process#GO:0010948;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012340.1|UniProtKB=W5N3J0 W5N3J0 PTHR10159:SF40 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;endoderm formation#GO:0001706;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;regulation of cellular process#GO:0050794;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;embryonic morphogenesis#GO:0048598 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000004477.1|UniProtKB=W5MAE6 W5MAE6 SPATA13 PTHR45834:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 13 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;filopodium assembly#GO:0046847;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012909.1|UniProtKB=W5N5I9 W5N5I9 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004193.1|UniProtKB=W5M9E7 W5M9E7 PTHR12015:SF193 SMALL INDUCIBLE CYTOKINE A STROMAL CELL-DERIVED FACTOR 1 cytokine#PC00083;intercellular signal molecule#PC00207 Axon guidance mediated by Slit/Robo#P00008>Sdf1#P00346 LEPOC|Ensembl=ENSLOCG00000000588.1|UniProtKB=W5LWZ3 W5LWZ3 PTHR33488:SF2 ZGC:162509 EARLY ENDOSOME ANTIGEN 1-LIKE LEPOC|Ensembl=ENSLOCG00000013395.1|UniProtKB=W5N7A4 W5N7A4 PTHR31239:SF2 NICOLIN 1 NICOLIN-1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007847.1|UniProtKB=W5MMB8 W5MMB8 PTHR31796:SF2 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017217.1|UniProtKB=W5NKX8 W5NKX8 PTHR11475:SF75 OXIDASE/PEROXIDASE PEROXIDASIN HOMOLOG oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006375.1|UniProtKB=W5MH40 W5MH40 PTHR23107:SF2 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN PROTEIN SSXT transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010355.1|UniProtKB=W5MWE5 W5MWE5 PTHR24210:SF13 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1 regulation of cell communication#GO:0010646;cell-cell junction organization#GO:0045216;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785;positive regulation of signaling#GO:0023056;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810 cytoplasm#GO:0005737;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 LEPOC|Ensembl=ENSLOCG00000005640.1|UniProtKB=W5MEK3 W5MEK3 PTHR45639:SF3 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000006917.1|UniProtKB=W5MJ01 W5MJ01 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000008292.1|UniProtKB=W5MNW5 W5MNW5 PTHR22939:SF13 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004085.1|UniProtKB=W5M919 W5M919 CTRL PTHR24250:SF66 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-LIKE PROTEASE CTRL-1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003697.1|UniProtKB=W5M7P1 W5M7P1 PTHR24068:SF153 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 W ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015333.1|UniProtKB=W5NE11 W5NE11 PTHR18945:SF211 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-4 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;chloride transmembrane transporter activity#GO:0015108;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010866.1|UniProtKB=W5MY54 W5MY54 PTHR26451:SF470 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012213.1|UniProtKB=W5N313 W5N313 PTHR31586:SF1 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011662.1|UniProtKB=W5N127 W5N127 PTHR46605:SF3 TUMOR NECROSIS FACTOR RECEPTOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 growth factor binding#GO:0019838;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008414.1|UniProtKB=W5MPB7 W5MPB7 PTHR11214:SF361 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000004592.1|UniProtKB=W5MAU1 W5MAU1 PTHR24064:SF196 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 31-RELATED secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012355.1|UniProtKB=W5N3J6 W5N3J6 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000002824.1|UniProtKB=W5M4M5 W5M4M5 PTHR15741:SF41 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR CARBOHYDRATE-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009996.1|UniProtKB=W5MV13 W5MV13 TMEM38B PTHR12454:SF5 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE B ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010916.1|UniProtKB=W5MYC8 W5MYC8 PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016820.1|UniProtKB=W5NJI0 W5NJI0 PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic hydroxy compound metabolic process#GO:1901615;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;alcohol metabolic process#GO:0006066;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010665.1|UniProtKB=W5MXF6 W5MXF6 PTHR10855:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 COP9 SIGNALOSOME COMPLEX SUBUNIT 4 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011360.1|UniProtKB=W5N019 W5N019 PTHR22957:SF195 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 4 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001941.1|UniProtKB=W5M1I8 W5M1I8 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;non-membrane-bounded organelle assembly#GO:0140694 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007765.1|UniProtKB=W5MM25 W5MM25 PTHR34093:SF1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017925.1|UniProtKB=W5NN19 W5NN19 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007672.1|UniProtKB=W5MLQ1 W5MLQ1 PTHR11183:SF164 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;glucan biosynthetic process#GO:0009250;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017612.1|UniProtKB=W5NM58 W5NM58 PTHR45134:SF5 OS08G0543275 PROTEIN OS08G0543275 PROTEIN LEPOC|Ensembl=ENSLOCG00000004684.1|UniProtKB=W5MB50 W5MB50 PTHR14759:SF29 STOP PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;transport#GO:0006810;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;microtubule cytoskeleton#GO:0015630;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000005387.1|UniProtKB=W5MDN4 W5MDN4 PTHR42757:SF9 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEUROTRIMIN defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003665.1|UniProtKB=W5M7K5 W5M7K5 PTHR13281:SF0 TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017001.1|UniProtKB=W5NK61 W5NK61 PTHR10694:SF17 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5A histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000018255.1|UniProtKB=W5NNZ7 W5NNZ7 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010563.1|UniProtKB=W5MX38 W5MX38 PTHR12241:SF145 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL5 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000013133.1|UniProtKB=W5N6B7 W5N6B7 ELOVL2 PTHR11157:SF16 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000002171.1|UniProtKB=W5M2D0 W5M2D0 UBQLN1 PTHR10677:SF16 UBIQUILIN UBIQUILIN-1 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013606.1|UniProtKB=W5N816 W5N816 PTHR11188:SF49 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011666.1|UniProtKB=W5N131 W5N131 PTHR13866:SF26 SPARC OSTEONECTIN SPARC cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000015455.1|UniProtKB=W5NEG2 W5NEG2 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014674.1|UniProtKB=W5NBR2 W5NBR2 PTHR46513:SF44 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LDL RECEPTOR RELATED PROTEIN 4 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000059.1|UniProtKB=W5LVB2 W5LVB2 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001646.1|UniProtKB=W5M0I7 W5M0I7 PTHR10390:SF73 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;sensory system development#GO:0048880;visual system development#GO:0150063;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009953.1|UniProtKB=W5MUX2 W5MUX2 PTHR24040:SF14 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN GROWTH ARREST-SPECIFIC PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000018097.1|UniProtKB=W5NNI9 W5NNI9 PTHR25462:SF229 BONUS, ISOFORM C-RELATED TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000778.1|UniProtKB=W5LXL3 W5LXL3 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 LEPOC|Ensembl=ENSLOCG00000011562.1|UniProtKB=W5N0Q5 W5N0Q5 PTHR31220:SF4 HYCCIN RELATED HYCCIN lipid metabolic process#GO:0006629;cellular localization#GO:0051641;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016028.1|UniProtKB=W5NGI5 W5NGI5 PTHR11202:SF11 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006916.1|UniProtKB=W5MJ11 W5MJ11 PTHR14516:SF2 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER NON-HOMOLOGOUS END JOINING FACTOR IFFO1 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006925.1|UniProtKB=W5MJ17 W5MJ17 PTHR10125:SF13 P2X PURINOCEPTOR P2X PURINOCEPTOR 7 monoatomic cation channel activity#GO:0005261;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002208.1|UniProtKB=W5M2G1 W5M2G1 PTHR13085:SF0 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal peptide processing#GO:0006465 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 protease#PC00190;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Signal Peptidase#P04589 LEPOC|Ensembl=ENSLOCG00000006343.1|UniProtKB=W5MH00 W5MH00 PTHR10356:SF5 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1-LIKE cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;actin filament binding#GO:0051015;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;actin binding#GO:0003779 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 supramolecular complex#GO:0099080;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;ruffle membrane#GO:0032587;actin cytoskeleton#GO:0015629;ruffle#GO:0001726;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014311.1|UniProtKB=W5NAG4 W5NAG4 PTHR15592:SF20 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006212.1|UniProtKB=W5MGJ3 W5MGJ3 PTHR35088:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 LEPOC|Ensembl=ENSLOCG00000012439.1|UniProtKB=W5N3V6 W5N3V6 PTHR42693:SF42 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE G hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010884.1|UniProtKB=W5MY83 W5MY83 PTHR32387:SF0 WU:FJ29H11 PROTEIN NO VEIN LEPOC|Ensembl=ENSLOCG00000000986.1|UniProtKB=W5LYA3 W5LYA3 PTHR45948:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED TYROSINE-PROTEIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005090.1|UniProtKB=W5MCM2 W5MCM2 PTHR16322:SF1 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000003718.1|UniProtKB=W5M7R0 W5M7R0 PTHR22776:SF28 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004842.1|UniProtKB=W5MBQ6 W5MBQ6 PTHR24410:SF21 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003954.1|UniProtKB=W5M8L1 W5M8L1 PTHR10772:SF0 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL cation binding#GO:0043169;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;chaperone cofactor-dependent protein refolding#GO:0051085;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000010577.1|UniProtKB=W5MX54 W5MX54 PTHR13134:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003842.1|UniProtKB=W5M886 W5M886 PTHR43557:SF8 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 3 oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016558.1|UniProtKB=W5NIJ4 W5NIJ4 PTHR20856:SF5 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000006915.1|UniProtKB=W5MJ31 W5MJ31 PTHR11347:SF139 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000000265.1|UniProtKB=W5LVY3 W5LVY3 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000001379.1|UniProtKB=W5LZK7 W5LZK7 PTHR23415:SF4 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000735.1|UniProtKB=W5LXF6 W5LXF6 PTHR12281:SF10 RP42 RELATED DCN1-LIKE PROTEIN 1 cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016283.1|UniProtKB=W5NHI2 W5NHI2 PTHR10024:SF239 SYNAPTOTAGMIN SYNAPTOTAGMIN-1 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000003562.1|UniProtKB=W5M757 W5M757 PTHR13044:SF3 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002386.1|UniProtKB=W5M342 W5M342 PTHR31179:SF5 RAB GTPASE-BINDING EFFECTOR PROTEIN RAB GTPASE-BINDING EFFECTOR PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014282.1|UniProtKB=W5NAC6 W5NAC6 PTHR13318:SF186 PARTNER OF PAIRED, ISOFORM B-RELATED DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;mitochondrial respiratory chain complex assembly#GO:0033108;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000016788.1|UniProtKB=W5NJE3 W5NJE3 PTHR24323:SF3 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009310.1|UniProtKB=W5MSL5 W5MSL5 PTHR45655:SF17 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 LEPOC|Ensembl=ENSLOCG00000004720.1|UniProtKB=W5MB99 W5MB99 PTHR46199:SF5 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular component biogenesis#GO:0044085;cell division#GO:0051301;signal transduction#GO:0007165;mitotic spindle organization#GO:0007052;small GTPase-mediated signal transduction#GO:0007264;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;spindle elongation#GO:0051231;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;cytoskeleton-dependent cytokinesis#GO:0061640;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;non-membrane-bounded organelle assembly#GO:0140694;cytokinesis#GO:0000910;signaling#GO:0023052;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;cellular response to stimulus#GO:0051716;sister chromatid segregation#GO:0000819;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285 spindle midzone#GO:0051233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell division site#GO:0032153;cytoskeleton#GO:0005856;spindle#GO:0005819;plasma membrane#GO:0005886 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004660.1|UniProtKB=W5MB19 W5MB19 PTHR45652:SF10 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT MEDIUM POLYPEPTIDE ISOFORM X1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;synapse#GO:0045202;intermediate filament#GO:0005882;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;postsynapse#GO:0098794;cytoskeleton#GO:0005856;cell projection#GO:0042995 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000003417.1|UniProtKB=W5M6P8 W5M6P8 GBP6 PTHR10751:SF105 GUANYLATE BINDING PROTEIN CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8 ISOFORM X1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000003263.1|UniProtKB=W5M644 W5M644 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000012745.1|UniProtKB=W5N4X0 W5N4X0 PTHR24118:SF99 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER 3C-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016215.1|UniProtKB=W5NH83 W5NH83 PTHR44499:SF1 JOUBERIN JOUBERIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016554.1|UniProtKB=W5NII5 W5NII5 RHNO1 PTHR35541:SF1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015359.1|UniProtKB=W5NE42 W5NE42 PTHR15710:SF160 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010058.1|UniProtKB=W5MV93 W5MV93 PTHR45776:SF4 MIP04163P MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000005714.1|UniProtKB=W5MEW3 W5MEW3 PTHR15154:SF2 HAMARTIN HAMARTIN regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 LEPOC|Ensembl=ENSLOCG00000003851.1|UniProtKB=W5M888 W5M888 PTHR11003:SF75 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 9 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413;Opioid proenkephalin pathway#P05915>K+ channel#P05990;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425 LEPOC|Ensembl=ENSLOCG00000011179.1|UniProtKB=W5MZD1 W5MZD1 PTHR18945:SF786 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A-LIKE-RELATED monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012147.1|UniProtKB=W5N2U1 W5N2U1 PTHR18934:SF85 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000017129.1|UniProtKB=W5NKL2 W5NKL2 PTHR24061:SF5 CALCIUM-SENSING RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001330.1|UniProtKB=W5LZF6 W5LZF6 PTHR10671:SF8 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011004.1|UniProtKB=W5MYP0 W5MYP0 PTHR16771:SF0 26 PROTEASOME COMPLEX SUBUNIT DSS1 26S PROTEASOME COMPLEX SUBUNIT SEM1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011282.1|UniProtKB=W5MZR6 W5MZR6 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014890.1|UniProtKB=W5NCI4 W5NCI4 PTHR46017:SF1 ALPHA-MANNOSIDASE 2C1 ALPHA-MANNOSIDASE 2C1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000007368.1|UniProtKB=W5MKN5 W5MKN5 PTHR13742:SF20 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;developmental process#GO:0032502;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle process#GO:0010948;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 LEPOC|Ensembl=ENSLOCG00000007242.1|UniProtKB=W5MK59 W5MK59 PTHR46983:SF4 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017988.1|UniProtKB=W5NN80 W5NN80 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000004932.1|UniProtKB=W5MC23 W5MC23 PTHR12357:SF9 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 3 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of mRNA metabolic process#GO:1903313;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;mRNA destabilization#GO:0061157;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002331.1|UniProtKB=W5M2X6 W5M2X6 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;protein kinase binding#GO:0019901;molecular function inhibitor activity#GO:0140678;double-stranded RNA binding#GO:0003725;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013075.1|UniProtKB=W5N653 W5N653 MCM7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009248.1|UniProtKB=W5MSB8 W5MSB8 PTHR24023:SF1002 COLLAGEN ALPHA OTOLIN-1-LIKE structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000006909.1|UniProtKB=W5MJ00 W5MJ00 PTHR10169:SF36 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-BETA cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 LEPOC|Ensembl=ENSLOCG00000013997.1|UniProtKB=W5N9E3 W5N9E3 NKX2-8 PTHR24340:SF27 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017440.1|UniProtKB=W5NLN6 W5NLN6 PTHR24231:SF38 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011541.1|UniProtKB=W5N0N5 W5N0N5 PTHR11453:SF10 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010741.1|UniProtKB=W5MXP7 W5MXP7 PTHR36466:SF1 BCL-2-LIKE PROTEIN 15 BCL-2-LIKE PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000000278.1|UniProtKB=W5LVZ8 W5LVZ8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007800.1|UniProtKB=W5MM56 W5MM56 PTHR10252:SF54 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008935.1|UniProtKB=W5MR73 W5MR73 PTHR23320:SF125 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED TRANSMEMBRANE PROTEIN 176L.1-RELATED transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008061.1|UniProtKB=W5MN25 W5MN25 TPPP PTHR12932:SF18 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000016205.1|UniProtKB=W5NH65 W5NH65 PTHR15073:SF4 MICROTUBULE-ASSOCIATED PROTEIN ENSCONSIN microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000008298.1|UniProtKB=W5MNW9 W5MNW9 PTHR21245:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 46-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006705.1|UniProtKB=W5MI91 W5MI91 PTHR14024:SF11 PERILIPIN PERILIPIN-3 localization#GO:0051179;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016480.1|UniProtKB=W5NI98 W5NI98 PTHR23055:SF101 CALCIUM BINDING PROTEINS VISININ-LIKE PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003559.1|UniProtKB=W5M775 W5M775 PTHR46070:SF2 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5A nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007786.1|UniProtKB=W5MM44 W5MM44 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000014549.1|UniProtKB=W5NB99 W5NB99 PTHR13604:SF0 DC12-RELATED ABASIC SITE PROCESSING PROTEIN HMCES LEPOC|Ensembl=ENSLOCG00000013935.1|UniProtKB=W5N976 W5N976 PTHR47130:SF6 SI:DKEY-19B23.11-RELATED EGG ENVELOPE GLYCOPROTEIN-LIKE PRECURSOR LEPOC|Ensembl=ENSLOCG00000015107.1|UniProtKB=W5NDA2 W5NDA2 PTHR12582:SF5 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000002426.1|UniProtKB=W5M391 W5M391 PTHR11085:SF5 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003199.1|UniProtKB=W5M5X3 W5M5X3 PTHR46789:SF2 FORKHEAD BOX PROTEIN R1 FORKHEAD BOX PROTEIN R2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000008431.1|UniProtKB=W5MPG4 W5MPG4 PTHR24223:SF196 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 5 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013120.1|UniProtKB=W5N6A2 W5N6A2 PTHR21646:SF74 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014314.1|UniProtKB=W5NAG6 W5NAG6 PTHR23147:SF52 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 7A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011131.1|UniProtKB=W5MZ66 W5MZ66 PTHR15885:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009773.1|UniProtKB=W5MU82 W5MU82 PTHR48033:SF1 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A_B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015561.1|UniProtKB=W5NEV4 W5NEV4 CCDC88A PTHR18947:SF30 HOOK PROTEINS GIRDIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005215.1|UniProtKB=W5MD20 W5MD20 PTHR31204:SF1 SIGMA INTRACELLULAR RECEPTOR 2 SIGMA INTRACELLULAR RECEPTOR 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003502.1|UniProtKB=W5M6Z3 W5M6Z3 PTHR23220:SF84 INTEGRIN ALPHA INTEGRIN ALPHA-L cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 LEPOC|Ensembl=ENSLOCG00000004470.1|UniProtKB=W5MAD5 W5MAD5 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;BRCA1-A complex#GO:0070531;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011716.1|UniProtKB=W5N1A4 W5N1A4 PTHR11347:SF191 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000000664.1|UniProtKB=W5LX77 W5LX77 C1orf216 PTHR35673:SF1 UPF0500 PROTEIN C1ORF216 UPF0500 PROTEIN C1ORF216 LEPOC|Ensembl=ENSLOCG00000012845.1|UniProtKB=W5N5A1 W5N5A1 BUB1B PTHR14030:SF25 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;catalytic activity#GO:0003824;protein kinase activity#GO:0004672 meiotic sister chromatid cohesion#GO:0051177;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;sister chromatid cohesion#GO:0007062;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010432.1|UniProtKB=W5MWN5 W5MWN5 PTHR11607:SF69 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008979.1|UniProtKB=W5MRD4 W5MRD4 FTSJ3 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016955.1|UniProtKB=W5NK01 W5NK01 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008696.1|UniProtKB=W5MQC2 W5MQC2 PTHR10264:SF87 BAND 7 PROTEIN-RELATED STOMATIN (EPB72)-LIKE 3A cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011607.1|UniProtKB=W5N0W0 W5N0W0 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lyase#PC00144;hydratase#PC00120 TCA cycle#P00051>Aconitase#P01268 LEPOC|Ensembl=ENSLOCG00000018367.1|UniProtKB=W5NPA9 W5NPA9 PTHR13259:SF1 BLADDER CANCER 10 KD PROTEIN HOMOLOG BLADDER CANCER-ASSOCIATED PROTEIN LEPOC|Ensembl=ENSLOCG00000016096.1|UniProtKB=W5NGS3 W5NGS3 PTHR11384:SF68 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 2-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;intracellular lipid transport#GO:0032365;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006594.1|UniProtKB=W5MHV6 W5MHV6 PTHR28574:SF1 RIKEN CDNA 6820408C15 RIKEN CDNA 6820408C15 GENE LEPOC|Ensembl=ENSLOCG00000016747.1|UniProtKB=W5NJ90 W5NJ90 PTHR14470:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 4 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001632.1|UniProtKB=W5M0G9 W5M0G9 PTHR10395:SF11 URICASE AND TRANSTHYRETIN-RELATED 5-HYDROXYISOURATE HYDROLASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010688.1|UniProtKB=W5MXI0 W5MXI0 PTHR20957:SF0 RNA-BINDING PROTEIN 48 RNA-BINDING PROTEIN 48 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016340.1|UniProtKB=W5NHR4 W5NHR4 PTHR10552:SF6 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004690.1|UniProtKB=W5MB61 W5MB61 PTHR10093:SF8 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME cation binding#GO:0043169;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008408.1|UniProtKB=W5MPB0 W5MPB0 PTHR10290:SF1 DNA TOPOISOMERASE I DNA TOPOISOMERASE I, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cell cycle#GO:0007049;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA topoisomerase#PC00017 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470;DNA replication#P00017>DNA Topisomerase#P00536 LEPOC|Ensembl=ENSLOCG00000010159.1|UniProtKB=W5MVN7 W5MVN7 DHX29 PTHR18934:SF264 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX29 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010086.1|UniProtKB=W5MVC7 W5MVC7 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 muscle organ development#GO:0007517;muscle cell differentiation#GO:0042692;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;cell development#GO:0048468;muscle cell development#GO:0055001;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000015879.1|UniProtKB=W5NFZ5 W5NFZ5 PTHR11220:SF24 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 LEPOC|Ensembl=ENSLOCG00000004171.1|UniProtKB=W5M9C6 W5M9C6 PTHR20981:SF6 60S RIBOSOMAL PROTEIN L21 60S RIBOSOMAL PROTEIN L21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005213.1|UniProtKB=W5MD16 W5MD16 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000015498.1|UniProtKB=W5NEL6 W5NEL6 PTHR13832:SF803 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1G macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016240.1|UniProtKB=W5NHB4 W5NHB4 PTHR12232:SF4 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008756.1|UniProtKB=W5MQL2 W5MQL2 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009781.1|UniProtKB=W5MUA4 W5MUA4 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000002760.1|UniProtKB=W5M4E5 W5M4E5 PTHR13459:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000015069.1|UniProtKB=W5ND35 W5ND35 PTHR10822:SF25 GLYPICAN GLYPICAN-4 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;regulation of cellular localization#GO:0060341;regulation of protein localization#GO:0032880 cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006940.1|UniProtKB=W5MJ39 W5MJ39 PTHR12143:SF19 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 LEPOC|Ensembl=ENSLOCG00000002351.1|UniProtKB=W5M332 W5M332 PTHR24257:SF19 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009976.1|UniProtKB=W5MUZ1 W5MUZ1 PTHR10621:SF13 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG B proteasome binding#GO:0070628;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011203.1|UniProtKB=W5MZF7 W5MZF7 PTHR14096:SF57 APOLIPOPROTEIN L APOLIPOPROTEIN L4 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000017405.1|UniProtKB=W5NLK1 W5NLK1 PTHR22911:SF137 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G2-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017144.1|UniProtKB=W5NKM8 W5NKM8 PTHR11949:SF1 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Toll receptor signaling pathway#P00054>IRF3#P01374 LEPOC|Ensembl=ENSLOCG00000009800.1|UniProtKB=W5MUB7 W5MUB7 PTHR14911:SF13 THUMP DOMAIN-CONTAINING TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000011587.1|UniProtKB=W5N0S8 W5N0S8 PTHR15592:SF41 MATRIN 3/NUCLEAR PROTEIN 220-RELATED MATRIN 3-LIKE ISOFORM X1 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016640.1|UniProtKB=W5NIU9 W5NIU9 PTHR21236:SF7 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF4 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;Golgi organization#GO:0007030;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001442.1|UniProtKB=W5LZT7 W5LZT7 PTHR23003:SF52 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 6 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006435.1|UniProtKB=W5MHB7 W5MHB7 PTHR24103:SF654 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN_ISG15 LIGASE TRIM25 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007458.1|UniProtKB=W5MKY9 W5MKY9 PTHR14983:SF1 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 LEPOC|Ensembl=ENSLOCG00000009377.1|UniProtKB=W5MSS8 W5MSS8 PTHR22089:SF2 MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000017786.1|UniProtKB=W5NMN1 W5NMN1 PTHR14499:SF29 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD12 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277 presynapse#GO:0098793;receptor complex#GO:0043235;synapse#GO:0045202;protein-containing complex#GO:0032991;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002871.1|UniProtKB=W5M4R3 W5M4R3 PTHR33618:SF1 39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML53 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011268.1|UniProtKB=W5MZN7 W5MZN7 PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;binding#GO:0005488;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000292.1|UniProtKB=W5LW13 W5LW13 PTHR46838:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of lymphocyte migration#GO:2000401;positive regulation of protein modification process#GO:0031401;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;positive regulation of cytokine production#GO:0001819;defense response#GO:0006952;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;defense response to Gram-positive bacterium#GO:0050830;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;defense response to Gram-negative bacterium#GO:0050829;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of leukocyte migration#GO:0002687;negative regulation of multicellular organismal process#GO:0051241;positive regulation of biosynthetic process#GO:0009891;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of leukocyte activation#GO:0002694;regulation of cellular biosynthetic process#GO:0031326;positive regulation of cell migration#GO:0030335;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002273.1|UniProtKB=W5M2Q5 W5M2Q5 PTHR11208:SF30 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014810.1|UniProtKB=W5NC75 W5NC75 PTHR10185:SF16 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD3 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000005337.1|UniProtKB=W5MDH3 W5MDH3 PTHR13844:SF1 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000016779.1|UniProtKB=W5NJD2 W5NJD2 PTHR23112:SF36 G PROTEIN-COUPLED RECEPTOR 157-RELATED SI:DKEY-30C15.2 PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011473.1|UniProtKB=W5N0E3 W5N0E3 PTHR22957:SF225 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9B nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002909.1|UniProtKB=W5M4W7 W5M4W7 FANCA PTHR12047:SF2 FANCONI ANEMIA GROUP A PROTEIN FANCONI ANEMIA GROUP A PROTEIN protein-containing complex#GO:0032991;Fanconi anaemia nuclear complex#GO:0043240;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016347.1|UniProtKB=W5NHS7 W5NHS7 PTHR12062:SF14 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE C acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012327.1|UniProtKB=W5N3G0 W5N3G0 PRR7 PTHR16209:SF3 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 PROLINE-RICH PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000010664.1|UniProtKB=W5MXG3 W5MXG3 PTHR11588:SF75 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015275.1|UniProtKB=W5NDU0 W5NDU0 PTHR46071:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006488.1|UniProtKB=W5MHH7 W5MHH7 PTHR14296:SF16 REMODELING AND SPACING FACTOR 1 REMODELING AND SPACING FACTOR 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000003552.1|UniProtKB=W5M744 W5M744 PTHR19855:SF16 WD40 REPEAT PROTEIN 12, 37 F-BOX AND WD REPEAT DOMAIN CONTAINING 8 LEPOC|Ensembl=ENSLOCG00000010966.1|UniProtKB=W5MYK1 W5MYK1 PTHR11947:SF22 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 4, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006566.1|UniProtKB=W5MHS3 W5MHS3 PTHR21737:SF6 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 SPLICING FACTOR CACTIN cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;negative regulation of innate immune response#GO:0045824;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;negative regulation of defense response#GO:0031348;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of immune system process#GO:0002682;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of defense response#GO:0031347;biological regulation#GO:0065007;mRNA processing#GO:0006397;negative regulation of response to external stimulus#GO:0032102;negative regulation of immune system process#GO:0002683;RNA splicing, via transesterification reactions#GO:0000375 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012256.1|UniProtKB=W5N374 W5N374 PTHR44305:SF24 SI:DKEY-192D15.2-RELATED TYROSINE-PROTEIN KINASE C03B1.5-RELATED LEPOC|Ensembl=ENSLOCG00000001813.1|UniProtKB=W5M132 W5M132 PTHR12080:SF134 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014443.1|UniProtKB=W5NAW8 W5NAW8 PTHR11875:SF108 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 3-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009552.1|UniProtKB=W5MTG8 W5MTG8 PTHR42961:SF2 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR PROTEIN NUBPL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000014302.1|UniProtKB=W5NAF0 W5NAF0 PTHR13710:SF153 DNA HELICASE RECQ FAMILY MEMBER RECQ-LIKE DNA HELICASE BLM ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015599.1|UniProtKB=W5NEZ6 W5NEZ6 PTHR21603:SF16 ANTIGEN KI-67-LIKE PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 2 regulation of biological process#GO:0050789;regulation of mitotic nuclear division#GO:0007088;regulation of nuclear division#GO:0051783;regulation of chromosome segregation#GO:0051983;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle process#GO:0010564 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009380.1|UniProtKB=W5MST4 W5MST4 PTHR24247:SF211 5-HYDROXYTRYPTAMINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002461.1|UniProtKB=W5M3D4 W5M3D4 PTHR46061:SF5 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 LEPOC|Ensembl=ENSLOCG00000011753.1|UniProtKB=W5N1F4 W5N1F4 SEMA4D PTHR11036:SF18 SEMAPHORIN SEMAPHORIN-4D molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of GTPase activity#GO:0043087;ossification#GO:0001503;positive regulation of locomotion#GO:0040017;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of hydrolase activity#GO:0051345;negative regulation of nitrogen compound metabolic process#GO:0051172;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;bone development#GO:0060348;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;regulation of biosynthetic process#GO:0009889;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular biosynthetic process#GO:0031326;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Axon guidance mediated by semaphorins#P00007>Sema4D#P00329 LEPOC|Ensembl=ENSLOCG00000009389.1|UniProtKB=W5MSV0 W5MSV0 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002646.1|UniProtKB=W5M402 W5M402 PTHR24168:SF23 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 3 regulation of anatomical structure size#GO:0090066;negative regulation of protein polymerization#GO:0032272;negative regulation of biological process#GO:0048519;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000006855.1|UniProtKB=W5MIT4 W5MIT4 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015098.1|UniProtKB=W5ND72 W5ND72 PTHR13924:SF12 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 1 head development#GO:0060322;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;animal organ development#GO:0048513;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;brain development#GO:0007420;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;forebrain development#GO:0030900;system development#GO:0048731;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016959.1|UniProtKB=W5NK06 W5NK06 PTHR13572:SF1 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005414.1|UniProtKB=W5MDS2 W5MDS2 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN 12 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015981.1|UniProtKB=W5NGB8 W5NGB8 PTHR13090:SF1 ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000007983.1|UniProtKB=W5MMT3 W5MMT3 PTHR13874:SF10 ENDOTHELIN ENDOTHELIN-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;positive regulation of catalytic activity#GO:0043085;system process#GO:0003008;positive regulation of molecular function#GO:0044093;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;regulation of systemic arterial blood pressure#GO:0003073;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;circulatory system process#GO:0003013;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of blood pressure#GO:0008217;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular monoatomic ion homeostasis#GO:0006873;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576 LEPOC|Ensembl=ENSLOCG00000016017.1|UniProtKB=W5NGH1 W5NGH1 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004642.1|UniProtKB=W5MB01 W5MB01 PTHR45652:SF10 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT MEDIUM POLYPEPTIDE ISOFORM X1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;synapse#GO:0045202;intermediate filament#GO:0005882;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;postsynapse#GO:0098794;cytoskeleton#GO:0005856;cell projection#GO:0042995 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000018189.1|UniProtKB=W5NNT1 W5NNT1 PTHR22750:SF8 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014052.1|UniProtKB=W5N9L2 W5N9L2 PTHR17130:SF14 MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013978.1|UniProtKB=W5N9B9 W5N9B9 PTHR21281:SF0 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008149.1|UniProtKB=W5MND6 W5MND6 PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000001184.1|UniProtKB=W5LYY4 W5LYY4 PTHR16007:SF59 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B LEPOC|Ensembl=ENSLOCG00000003834.1|UniProtKB=W5M891 W5M891 CCDC158 PTHR47615:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 LEPOC|Ensembl=ENSLOCG00000003734.1|UniProtKB=W5M7V1 W5M7V1 KHDRBS3 PTHR11208:SF29 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008768.1|UniProtKB=W5MQM0 W5MQM0 PTHR44170:SF40 PROTEIN SIDEKICK IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 3 ISOFORM X1-RELATED cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000624.1|UniProtKB=W5LX33 W5LX33 PTHR12763:SF56 FAMILY NOT NAMED MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM14 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000015133.1|UniProtKB=W5NDC2 W5NDC2 PTHR21328:SF23 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP6 protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;pentosyltransferase activity#GO:0016763;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;protein serine/threonine kinase activator activity#GO:0043539;protein binding#GO:0005515 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 envelope#GO:0031975;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000008823.1|UniProtKB=W5MQS9 W5MQS9 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008236.1|UniProtKB=W5MNP1 W5MNP1 PTHR14499:SF10 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD6 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001033.1|UniProtKB=W5LYI6 W5LYI6 PTHR23169:SF10 ENVOPLAKIN PERIPLAKIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;wound healing#GO:0042060;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000001900.1|UniProtKB=W5M1E2 W5M1E2 PTHR11636:SF128 POU DOMAIN POU DOMAIN PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006963.1|UniProtKB=W5MJ62 W5MJ62 PTHR10812:SF9 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2 GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016294.1|UniProtKB=W5NHK2 W5NHK2 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003749.1|UniProtKB=W5M7V5 W5M7V5 PTHR24369:SF174 ANTIGEN BSP, PUTATIVE-RELATED RETICULON-4 RECEPTOR carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013598.1|UniProtKB=W5N813 W5N813 PTHR11610:SF2 LIPASE HEPATIC TRIACYLGLYCEROL LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 LEPOC|Ensembl=ENSLOCG00000012419.1|UniProtKB=W5N3T4 W5N3T4 PTHR46106:SF5 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE N2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;regulation of localization#GO:0032879;peptide secretion#GO:0002790;cellular homeostasis#GO:0019725;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular response to oxygen-containing compound#GO:1901701;hormone secretion#GO:0046879;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;peptide hormone secretion#GO:0030072;signal release#GO:0023061;insulin secretion#GO:0030073;hormone transport#GO:0009914;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;cell communication#GO:0007154;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;regulation of hormone levels#GO:0010817;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;response to stimulus#GO:0050896;intracellular glucose homeostasis#GO:0001678;response to glucose#GO:0009749;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;carbohydrate homeostasis#GO:0033500 cytoplasm#GO:0005737;synapse#GO:0045202;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014064.1|UniProtKB=W5N9N5 W5N9N5 PTHR15976:SF14 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000579.1|UniProtKB=W5LWY4 W5LWY4 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mediator complex#GO:0016592;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013491.1|UniProtKB=W5N7P3 W5N7P3 PTHR11915:SF248 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, ERYTHROCYTIC cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006803.1|UniProtKB=W5MIK9 W5MIK9 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 LEPOC|Ensembl=ENSLOCG00000005486.1|UniProtKB=W5ME11 W5ME11 PTHR15169:SF0 DAMAGE-SPECIFIC DNA BINDING PROTEIN 2 DNA DAMAGE-BINDING PROTEIN 2 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to UV#GO:0009411;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 p53 pathway#P00059>p48#G04705 LEPOC|Ensembl=ENSLOCG00000009943.1|UniProtKB=W5MUV5 W5MUV5 PTHR19964:SF11 MULTIPLE PDZ DOMAIN PROTEIN INAD-LIKE PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;apical junction complex#GO:0043296 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017852.1|UniProtKB=W5NMU6 W5NMU6 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000007261.1|UniProtKB=W5MK75 W5MK75 PTHR10686:SF37 FOLATE TRANSPORTER THIAMINE TRANSPORTER 2 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003512.1|UniProtKB=W5M6Z7 W5M6Z7 PTHR10417:SF3 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011021.1|UniProtKB=W5MYR7 W5MYR7 PTHR46528:SF1 PROTEIN SON PROTEIN SON RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011419.1|UniProtKB=W5N077 W5N077 TMEM150B PTHR21324:SF3 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED MODULATOR OF MACROAUTOPHAGY TMEM150B cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015403.1|UniProtKB=W5NE93 W5NE93 PTHR10528:SF18 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001823.1|UniProtKB=W5M154 W5M154 PTHR14392:SF3 NIBAN FAMILY MEMBER PROTEIN NIBAN 1 LEPOC|Ensembl=ENSLOCG00000012047.1|UniProtKB=W5N2F9 W5N2F9 PTHR46269:SF4 EPIPHYCAN-RELATED OPTICIN system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;skeletal system development#GO:0001501;tissue development#GO:0009888;bone development#GO:0060348 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005077.1|UniProtKB=W5MCL1 W5MCL1 PTHR24356:SF322 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;PDGF signaling pathway#P00047>PKC#P01150 LEPOC|Ensembl=ENSLOCG00000018262.1|UniProtKB=W5NP04 W5NP04 GP9 PTHR22650:SF6 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IX Blood coagulation#P00011>GP IX#P00455 LEPOC|Ensembl=ENSLOCG00000006368.1|UniProtKB=W5MH47 W5MH47 PTHR11533:SF239 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004800.1|UniProtKB=W5MBK0 W5MBK0 PTHR13080:SF17 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;oxidative phosphorylation#GO:0006119;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012788.1|UniProtKB=W5N525 W5N525 PTHR10551:SF9 FASCIN FASCIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament bundle assembly#GO:0051017;cell motility#GO:0048870;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004416.1|UniProtKB=W5MA64 W5MA64 HPR PTHR24256:SF524 TRYPTASE-RELATED HAPTOGLOBIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017434.1|UniProtKB=W5NLN0 W5NLN0 PTHR12002:SF89 CLAUDIN CLAUDIN-4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000007961.1|UniProtKB=W5MMR0 W5MMR0 PTHR45917:SF4 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 4 transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012245.1|UniProtKB=W5N353 W5N353 PTHR24349:SF63 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein kinase binding#GO:0019901;mitogen-activated protein kinase binding#GO:0051019;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;activation of immune response#GO:0002253;response to cytokine#GO:0034097;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;vascular endothelial growth factor receptor signaling pathway#GO:0048010;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;signal transduction#GO:0007165;response to growth factor#GO:0070848;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;pattern recognition receptor signaling pathway#GO:0002221;peptidyl-serine phosphorylation#GO:0018105;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of response to biotic stimulus#GO:0002833 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Ras Pathway#P04393>MAPKAP#P04564;Interleukin signaling pathway#P00036>MAPKAPK2#P00979;PDGF signaling pathway#P00047>MAPKAPK2#P01157;p38 MAPK pathway#P05918>MAPKAP-K2#P05920;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Angiogenesis#P00005>MAPKAPK2/3#P00244 LEPOC|Ensembl=ENSLOCG00000003061.1|UniProtKB=W5M5D8 W5M5D8 PTHR10969:SF4 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014152.1|UniProtKB=W5N9Y7 W5N9Y7 PTHR24416:SF52 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;skeletal system development#GO:0001501;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;chordate embryonic development#GO:0043009;response to stimulus#GO:0050896;embryonic organ development#GO:0048568;enzyme-linked receptor protein signaling pathway#GO:0007167;embryo development#GO:0009790;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor A#P01158;Angiogenesis#P00005>PDGFR#P00230 LEPOC|Ensembl=ENSLOCG00000015127.1|UniProtKB=W5NDC3 W5NDC3 PTHR46026:SF2 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;cellular component organization#GO:0016043;plasma membrane bounded cell projection assembly#GO:0120031;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cell leading edge#GO:0031252;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017544.1|UniProtKB=W5NLZ0 W5NLZ0 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015171.1|UniProtKB=W5NDG1 W5NDG1 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271 DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 LEPOC|Ensembl=ENSLOCG00000015447.1|UniProtKB=W5NEF4 W5NEF4 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;phosphate ion transport#GO:0006817;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transport#GO:0015698 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010807.1|UniProtKB=W5MY00 W5MY00 PTHR11905:SF13 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 23 presynapse#GO:0098793;synapse#GO:0045202;cell junction#GO:0030054;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009337.1|UniProtKB=W5MSN0 W5MSN0 PTHR15317:SF1 T-CELL SURFACE PROTEIN TACTILE T-CELL SURFACE PROTEIN TACTILE response to stimulus#GO:0050896;response to stress#GO:0006950;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;defense response#GO:0006952;cellular process#GO:0009987;inflammatory response#GO:0006954 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004326.1|UniProtKB=W5M9V8 W5M9V8 PTHR23007:SF13 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;aminoacyltransferase activity#GO:0016755;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;SH3 domain binding#GO:0017124;transferase activity#GO:0016740;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of protein kinase activity#GO:0006469;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of kinase activity#GO:0043549;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of ERBB signaling pathway#GO:1901184;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016974.1|UniProtKB=W5NK22 W5NK22 KICS2 PTHR31581:SF1 KICSTOR COMPLEX PROTEIN C12ORF66 KICSTOR SUBUNIT 2 cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;protein localization to vacuole#GO:0072665;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;negative regulation of TORC1 signaling#GO:1904262 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000003166.1|UniProtKB=W5M5U6 W5M5U6 PTHR24248:SF154 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(3) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;regulation of metal ion transport#GO:0010959;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;negative regulation of lyase activity#GO:0051350;negative regulation of cell communication#GO:0010648;regulation of monoatomic ion transmembrane transport#GO:0034765;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;response to nitrogen compound#GO:1901698;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;negative regulation of monoatomic ion transport#GO:0043271;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;negative regulation of cyclase activity#GO:0031280;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of adenylate cyclase activity#GO:0007194;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965 LEPOC|Ensembl=ENSLOCG00000002999.1|UniProtKB=W5M578 W5M578 PTHR11097:SF14 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP45 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;snRNA processing#GO:0016180;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;exosome (RNase complex)#GO:0000178 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000005904.1|UniProtKB=W5MFG7 W5MFG7 PTHR47978:SF4 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33B-LIKE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;regulation of transport#GO:0051049;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;autophagy#GO:0006914;regulation of exocytosis#GO:0017157;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012624.1|UniProtKB=W5N4H9 W5N4H9 LEMD2 PTHR13428:SF8 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN LEM DOMAIN-CONTAINING PROTEIN 2 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;membrane organization#GO:0061024;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular component organization or biogenesis#GO:0071840;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;nuclear envelope organization#GO:0006998;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000001856.1|UniProtKB=W5M192 W5M192 PTHR12080:SF80 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000740.1|UniProtKB=W5LXG9 W5LXG9 ABHD1 PTHR10794:SF60 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015970.1|UniProtKB=W5NGA4 W5NGA4 PTHR24348:SF73 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SI:CH211-63O20.7 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;neuron projection extension#GO:1990138;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;reticulophagy#GO:0061709;response to stress#GO:0006950;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of catabolic process#GO:0009896;autophagosome assembly#GO:0000045;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;macromolecule modification#GO:0043412;positive regulation of cellular catabolic process#GO:0031331;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell projection morphogenesis#GO:0048858;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;system development#GO:0048731;cell differentiation#GO:0030154;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;axon extension#GO:0048675;neuron differentiation#GO:0030182;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;regulation of autophagy#GO:0010506;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell morphogenesis#GO:0000902;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;cell growth#GO:0016049;organelle disassembly#GO:1903008;cell development#GO:0048468;organelle assembly#GO:0070925;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;response to starvation#GO:0042594;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;generation of neurons#GO:0048699 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003118.1|UniProtKB=W5M5K9 W5M5K9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013955.1|UniProtKB=W5N990 W5N990 PTHR46456:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;double-stranded DNA binding#GO:0003690;four-way junction DNA binding#GO:0000400 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005404.1|UniProtKB=W5MDQ8 W5MDQ8 DDAH1 PTHR12737:SF17 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE N(G),N(G)-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 positive regulation of nitrogen compound metabolic process#GO:0051173;oxoacid metabolic process#GO:0043436;regulation of nitrogen compound metabolic process#GO:0051171;arginine metabolic process#GO:0006525;positive regulation of cellular metabolic process#GO:0031325;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;alpha-amino acid metabolic process#GO:1901605;carboxylic acid metabolic process#GO:0019752;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;amino acid metabolic process#GO:0006520;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009564.1|UniProtKB=W5MTI5 W5MTI5 PTHR10288:SF93 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;mRNA stabilization#GO:0048255;multicellular organism development#GO:0007275;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003803.1|UniProtKB=W5M826 W5M826 PTHR12109:SF3 RING FINGER PROTEIN 141-RELATED RING FINGER PROTEIN 141 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000014018.1|UniProtKB=W5N9H9 W5N9H9 PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase#PC00079;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000017564.1|UniProtKB=W5NM10 W5NM10 PTHR15344:SF2 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;small GTPase-mediated signal transduction#GO:0007264;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of anatomical structure size#GO:0090066;cellular response to stimulus#GO:0051716;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005528.1|UniProtKB=W5ME66 W5ME66 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009004.1|UniProtKB=W5MRH3 W5MRH3 ANO7 PTHR12308:SF22 ANOCTAMIN ANOCTAMIN-7 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;membrane organization#GO:0061024;monoatomic anion transmembrane transport#GO:0098656;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;chloride transmembrane transport#GO:1902476;chloride transport#GO:0006821;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014670.1|UniProtKB=W5NBQ5 W5NBQ5 PTHR24351:SF192 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015891.1|UniProtKB=W5NG11 W5NG11 PTHR10684:SF1 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;nuclear receptor binding#GO:0016922;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000018061.1|UniProtKB=W5NNF3 W5NNF3 PTHR24228:SF9 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR 25-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003808.1|UniProtKB=W5M832 W5M832 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008412.1|UniProtKB=W5MPB5 W5MPB5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017862.1|UniProtKB=W5NMV6 W5NMV6 PTHR36542:SF7 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREO cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008614.1|UniProtKB=W5MQ10 W5MQ10 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001162.1|UniProtKB=W5LYU9 W5LYU9 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000003839.1|UniProtKB=W5M876 W5M876 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010207.1|UniProtKB=W5MVU0 W5MVU0 PTHR14338:SF8 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;SH3 domain binding#GO:0017124;binding#GO:0005488 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000536.1|UniProtKB=W5LWX7 W5LWX7 PTHR15286:SF11 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000320.1|UniProtKB=W5LW39 W5LW39 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015023.1|UniProtKB=W5NCY4 W5NCY4 PTHR12901:SF14 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015714.1|UniProtKB=W5NFD5 W5NFD5 PTHR15323:SF6 D123 PROTEIN CELL DIVISION CYCLE PROTEIN 123 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014385.1|UniProtKB=W5NAQ2 W5NAQ2 PTHR24026:SF38 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000013212.1|UniProtKB=W5N6L4 W5N6L4 PTHR43798:SF5 MONOACYLGLYCEROL LIPASE MONOACYLGLYCEROL LIPASE ABHD6 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;membrane#GO:0016020 lipase#PC00143 LEPOC|Ensembl=ENSLOCG00000013579.1|UniProtKB=W5N7Y4 W5N7Y4 PTHR15594:SF1 PODOCALYXIN-LIKE PROTEIN 2 PODOCALYXIN-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000008321.1|UniProtKB=W5MP02 W5MP02 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000015128.1|UniProtKB=W5NDA7 W5NDA7 PTHR42681:SF1 MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000013511.1|UniProtKB=W5N7Q3 W5N7Q3 PTHR16021:SF25 MANSC DOMAIN CONTAINING PROTEIN 1 MANSC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012526.1|UniProtKB=W5N467 W5N467 PTHR47977:SF102 RAS-RELATED PROTEIN RAB RAB44, MEMBER RAS ONCOGENE FAMILY GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005811.1|UniProtKB=W5MF60 W5MF60 PTHR11873:SF2 RETINOL-BINDING PROTEIN 4 RETINOL-BINDING PROTEIN 4 lipid binding#GO:0008289;small molecule binding#GO:0036094;alcohol binding#GO:0043178;binding#GO:0005488 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014583.1|UniProtKB=W5NBD7 W5NBD7 PTHR10231:SF106 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSLOCATOR transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009880.1|UniProtKB=W5MUP4 W5MUP4 PTHR22754:SF34 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG A cell surface#GO:0009986;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013770.1|UniProtKB=W5N8N1 W5N8N1 MAOA PTHR43563:SF23 AMINE OXIDASE AMINE OXIDASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016666.1|UniProtKB=W5NIY2 W5NIY2 PTHR22988:SF28 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;macromolecule modification#GO:0043412;developmental process#GO:0032502;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;protein metabolic process#GO:0019538;cytokinesis#GO:0000910;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;embryo development#GO:0009790;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;actin cytoskeleton organization#GO:0030036;embryonic morphogenesis#GO:0048598;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 LEPOC|Ensembl=ENSLOCG00000013873.1|UniProtKB=W5N903 W5N903 PTHR15995:SF1 PROTEIN ZWILCH HOMOLOG PROTEIN ZWILCH HOMOLOG negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;macromolecule localization#GO:0033036;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;protein localization to kinetochore#GO:0034501;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;protein localization to organelle#GO:0033365;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;negative regulation of chromosome separation#GO:1905819;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008304.1|UniProtKB=W5MNY3 W5MNY3 GALNT3 PTHR11675:SF33 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005719.1|UniProtKB=W5MEU2 W5MEU2 PTHR45925:SF2 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 536 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007323.1|UniProtKB=W5MKH0 W5MKH0 PTHR22829:SF5 DEP DOMAIN PROTEIN INTEGRAL MEMBRANE PROTEIN GPR155 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007511.1|UniProtKB=W5ML56 W5ML56 PTHR48122:SF1 CENTROMERE PROTEIN H CENTROMERE PROTEIN H binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687 LEPOC|Ensembl=ENSLOCG00000004560.1|UniProtKB=W5MAQ0 W5MAQ0 NABP2 PTHR13356:SF3 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B1 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;double-strand break repair#GO:0006302;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of mitotic cell cycle#GO:0045930;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000003910.1|UniProtKB=W5M8F8 W5M8F8 PTHR35085:SF1 KERATINOCYTE DIFFERENTIATION FACTOR 1 KERATINOCYTE DIFFERENTIATION FACTOR 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell division#GO:0051302;regulation of cellular process#GO:0050794 cell junction#GO:0030054;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003711.1|UniProtKB=W5M7V3 W5M7V3 PTHR11557:SF0 PORPHOBILINOGEN DEAMINASE PORPHOBILINOGEN DEAMINASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983 LEPOC|Ensembl=ENSLOCG00000009925.1|UniProtKB=W5MUT0 W5MUT0 PTHR12259:SF4 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011090.1|UniProtKB=W5MZ13 W5MZ13 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002647.1|UniProtKB=W5M404 W5M404 PTHR13723:SF147 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007763.1|UniProtKB=W5MM18 W5MM18 EIF6 PTHR10784:SF0 TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;maturation of 5.8S rRNA#GO:0000460;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of LSU-rRNA#GO:0000470 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000015459.1|UniProtKB=W5NEG7 W5NEG7 PTHR19302:SF70 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000004571.1|UniProtKB=W5MAR8 W5MAR8 PTHR43294:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007064.1|UniProtKB=W5MJJ4 W5MJJ4 PTHR28638:SF1 CELL CYCLE PROGRESSION PROTEIN 1 PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-INTERACTING PROTEIN 1 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004879.1|UniProtKB=W5MBW0 W5MBW0 PTHR13339:SF0 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003396.1|UniProtKB=W5M6M0 W5M6M0 PTHR11461:SF50 SERINE PROTEASE INHIBITOR, SERPIN NEUROSERPIN peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000017469.1|UniProtKB=W5NLR5 W5NLR5 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003759.1|UniProtKB=W5M7X0 W5M7X0 PTHR14021:SF15 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005230.1|UniProtKB=W5MD38 W5MD38 PTHR31978:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;ciliary base#GO:0097546;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000004588.1|UniProtKB=W5MAV3 W5MAV3 PTHR21207:SF2 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PARKIN COREGULATED GENE PROTEIN heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;Hsp90 protein binding#GO:0051879 LEPOC|Ensembl=ENSLOCG00000012394.1|UniProtKB=W5N3R1 W5N3R1 PTHR12450:SF12 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 PSEUDOKINASE FAM20A protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;transferase activity#GO:0016740;molecular function activator activity#GO:0140677;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 odontogenesis of dentin-containing tooth#GO:0042475;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;odontogenesis#GO:0042476;anatomical structure morphogenesis#GO:0009653;amelogenesis#GO:0097186;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;biomineral tissue development#GO:0031214;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016016.1|UniProtKB=W5NGH0 W5NGH0 GNAI1 PTHR10218:SF359 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Gonadotropin-releasing hormone receptor pathway#P06664>gnai/o#P06773;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid prodynorphin pathway#P05916>G-protein#P06002;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proenkephalin pathway#P05915>G-protein#P05994;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873 LEPOC|Ensembl=ENSLOCG00000014605.1|UniProtKB=W5NBG4 W5NBG4 GAB3 PTHR45960:SF3 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 3 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000009278.1|UniProtKB=W5MSF8 W5MSF8 ZHX1 PTHR15467:SF4 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000015530.1|UniProtKB=W5NER0 W5NER0 PTHR24261:SF8 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of programmed cell death#GO:0043067;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017643.1|UniProtKB=W5NM89 W5NM89 PTHR22750:SF16 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013793.1|UniProtKB=W5N8Q1 W5N8Q1 PTHR23064:SF47 TROPONIN TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001199.1|UniProtKB=W5LYZ4 W5LYZ4 TUBB3 PTHR11588:SF43 TUBULIN TUBULIN BETA-3 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 LEPOC|Ensembl=ENSLOCG00000003972.1|UniProtKB=W5M8N9 W5M8N9 PTHR23103:SF13 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;central nervous system development#GO:0007417;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000005618.1|UniProtKB=W5MEH2 W5MEH2 PHF21A PTHR24102:SF6 PHD FINGER PROTEIN PHD FINGER PROTEIN 21A protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000016900.1|UniProtKB=W5NJT1 W5NJT1 PTHR31514:SF1 MUSCULAR LMNA-INTERACTING PROTEIN MLIP MUSCULAR LMNA-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000000512.1|UniProtKB=W5LWQ7 W5LWQ7 PTHR47980:SF23 LD44762P RAB10, MEMBER RAS ONCOGENE FAMILY cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 LEPOC|Ensembl=ENSLOCG00000014119.1|UniProtKB=W5N9T5 W5N9T5 PTHR45704:SF6 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11B LEPOC|Ensembl=ENSLOCG00000000243.1|UniProtKB=W5LVW2 W5LVW2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012695.1|UniProtKB=W5N4R1 W5N4R1 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotide phosphatase#PC00173;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005692.1|UniProtKB=W5MES9 W5MES9 PTHR23323:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle localization#GO:0051640;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vacuole organization#GO:0007033;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;organelle fusion#GO:0048284;secretion by cell#GO:0032940 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015531.1|UniProtKB=W5NEQ5 W5NEQ5 PTHR15205:SF2 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017245.1|UniProtKB=W5NL21 W5NL21 PTHR31075:SF2 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA-LIKE intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000015144.1|UniProtKB=W5NDC9 W5NDC9 PTHR13516:SF5 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;endoribonuclease complex#GO:1902555;ribonuclease MRP complex#GO:0000172;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011319.1|UniProtKB=W5MZV9 W5MZV9 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;exosome (RNase complex)#GO:0000178 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000013302.1|UniProtKB=W5N6Y4 W5N6Y4 PTHR11360:SF19 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001370.1|UniProtKB=W5LZN3 W5LZN3 PTHR12920:SF2 RYBP AND YAF2-RELATED YY1-ASSOCIATED FACTOR 2 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000005452.1|UniProtKB=W5MDW9 W5MDW9 SYDE2 PTHR46150:SF1 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 synapse#GO:0045202;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009462.1|UniProtKB=W5MT43 W5MT43 PTHR28635:SF1 TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN LEPOC|Ensembl=ENSLOCG00000003946.1|UniProtKB=W5M8K1 W5M8K1 PYURF PTHR33505:SF4 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000007145.1|UniProtKB=W5MJT9 W5MJT9 PTHR24353:SF24 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 LEPOC|Ensembl=ENSLOCG00000011804.1|UniProtKB=W5N1K7 W5N1K7 PTHR11592:SF32 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 3 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003390.1|UniProtKB=W5M6K4 W5M6K4 AKIP1 PTHR14330:SF2 A-KINASE-INTERACTING PROTEIN 1 A-KINASE-INTERACTING PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012833.1|UniProtKB=W5N583 W5N583 PTHR12128:SF66 DIHYDRODIPICOLINATE SYNTHASE 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 lyase#PC00144 Lysine biosynthesis#P02751>Dihydrodipicolinate synthase#P03008 LEPOC|Ensembl=ENSLOCG00000005744.1|UniProtKB=W5MEZ0 W5MEZ0 PTHR24351:SF241 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016624.1|UniProtKB=W5NIS8 W5NIS8 PTHR10516:SF455 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYLPROLYL ISOMERASE peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 LEPOC|Ensembl=ENSLOCG00000004986.1|UniProtKB=W5MC93 W5MC93 NKAIN3 PTHR13084:SF2 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 3 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959 LEPOC|Ensembl=ENSLOCG00000001334.1|UniProtKB=W5LZG1 W5LZG1 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;enzyme regulator activity#GO:0030234 response to external biotic stimulus#GO:0043207;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;detection of stimulus#GO:0051606;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;negative regulation of nitrogen compound metabolic process#GO:0051172;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000005251.1|UniProtKB=W5MD63 W5MD63 PTHR47620:SF1 CHROMOSOME 2 OPEN READING FRAME 66 GENE, 34066-RELATED LEPOC|Ensembl=ENSLOCG00000000041.1|UniProtKB=W5LV91 W5LV91 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016342.1|UniProtKB=W5NHR8 W5NHR8 PTHR10334:SF568 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE RICH SECRETORY PROTEIN 3 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014368.1|UniProtKB=W5NAR8 W5NAR8 COL4A5 PTHR24023:SF1019 COLLAGEN ALPHA COLLAGEN ALPHA-5(IV) CHAIN ISOFORM X1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000005608.1|UniProtKB=W5MEF8 W5MEF8 PTHR11346:SF32 GALECTIN GALECTIN-4 carbohydrate binding#GO:0030246;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017634.1|UniProtKB=W5NM80 W5NM80 PTHR24156:SF7 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34B-LIKE LEPOC|Ensembl=ENSLOCG00000006284.1|UniProtKB=W5MGS9 W5MGS9 PTHR10464:SF4 UREA TRANSPORTER UREA TRANSPORTER transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010395.1|UniProtKB=W5MWI2 W5MWI2 PTHR21252:SF2 TB1 PROTEIN-RELATED MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fission#GO:0000266 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000007986.1|UniProtKB=W5MMU1 W5MMU1 PTHR16105:SF0 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING REGION-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;U12-type spliceosomal complex#GO:0005689 LEPOC|Ensembl=ENSLOCG00000016048.1|UniProtKB=W5NGL0 W5NGL0 PTHR31878:SF0 CHEMOKINE-LIKE PROTEIN TAFA-5-RELATED CHEMOKINE-LIKE PROTEIN TAFA-5 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000003124.1|UniProtKB=W5M5M3 W5M5M3 PTHR21600:SF83 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012990.1|UniProtKB=W5N5T8 W5N5T8 PTHR11829:SF385 FORKHEAD BOX PROTEIN FORKHEAD BOX Q1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016829.1|UniProtKB=W5NJJ1 W5NJJ1 PTHR46708:SF10 TENASCIN RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA-LIKE extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010977.1|UniProtKB=W5MYL2 W5MYL2 PTHR12546:SF37 FER-1-LIKE FER-1-LIKE 6 (C. ELEGANS) endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012127.1|UniProtKB=W5N2R1 W5N2R1 PTHR48013:SF15 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>Jnk#P00951;FAS signaling pathway#P00020>MKK4#P00610;p38 MAPK pathway#P05918>MKK4#P06034;Huntington disease#P00029>MAPKK4#P00787;Ras Pathway#P04393>MKK4/7#P04565;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;Huntington disease#P00029>SEK-1#P00792;Apoptosis signaling pathway#P00006>SEK1#P00266;Angiogenesis#P00005>JNKK1#P00199;Toll receptor signaling pathway#P00054>MKK4#P01366;FGF signaling pathway#P00021>MKK4,7#P00637;Integrin signalling pathway#P00034>MEK#P00925;EGF receptor signaling pathway#P00018>MKK4,7#P00555;Oxidative stress response#P00046>MKK4#P01138;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 LEPOC|Ensembl=ENSLOCG00000016670.1|UniProtKB=W5NIY4 W5NIY4 PTHR11486:SF150 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000007039.1|UniProtKB=W5MJG1 W5MJG1 PTHR24086:SF42 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NR5A5 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011383.1|UniProtKB=W5N050 W5N050 HDAC9 PTHR10625:SF41 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 9 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000007898.1|UniProtKB=W5MMI0 W5MMI0 PTHR36877:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 13 SMALL INTEGRAL MEMBRANE PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000008726.1|UniProtKB=W5MQF7 W5MQF7 PTHR28399:SF1 BARTTIN BARTTIN transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 localization#GO:0051179;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006407.1|UniProtKB=W5MH80 W5MH80 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000786.1|UniProtKB=W5LXL9 W5LXL9 SNTA1 PTHR10554:SF6 SYNTROPHIN ALPHA-1-SYNTROPHIN membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886;sarcolemma#GO:0042383;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016927.1|UniProtKB=W5NJW5 W5NJW5 PTHR10231:SF66 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER CMP-SIALIC ACID TRANSPORTER carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014709.1|UniProtKB=W5NBV0 W5NBV0 PTHR46458:SF2 BLR2807 PROTEIN X GLOBIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010389.1|UniProtKB=W5MWH8 W5MWH8 PTHR21228:SF1 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA processing#GO:0000963;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000015807.1|UniProtKB=W5NFQ0 W5NFQ0 PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003418.1|UniProtKB=W5M6N5 W5M6N5 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006131.1|UniProtKB=W5MG99 W5MG99 PTHR47189:SF1 MHC CLASS II TRANSACTIVATOR MHC CLASS II TRANSACTIVATOR positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000013037.1|UniProtKB=W5N608 W5N608 RHO PTHR24240:SF15 OPSIN RHODOPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 LEPOC|Ensembl=ENSLOCG00000016077.1|UniProtKB=W5NGQ2 W5NGQ2 PTHR23358:SF4 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET3 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;DNA modification#GO:0006304;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;DNA demethylation#GO:0080111;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005975.1|UniProtKB=W5MFR0 W5MFR0 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017794.1|UniProtKB=W5NMN9 W5NMN9 PTHR14315:SF19 SPOT14 FAMILY MEMBER MID1-INTERACTING PROTEIN 1-B-RELATED biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007923.1|UniProtKB=W5MML6 W5MML6 PTHR24390:SF83 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN CONTAINING 17 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013098.1|UniProtKB=W5N691 W5N691 PTHR11199:SF10 STROMAL ANTIGEN COHESIN SUBUNIT SA protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cohesin complex#GO:0008278;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003009.1|UniProtKB=W5M592 W5M592 SCMH1 PTHR12247:SF68 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCMH1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014537.1|UniProtKB=W5NB87 W5NB87 PTHR19328:SF58 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000290.1|UniProtKB=W5LW25 W5LW25 PTHR11984:SF1 CONNEXIN GAP JUNCTION EPSILON-1 PROTEIN-RELATED wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000010865.1|UniProtKB=W5MY55 W5MY55 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012012.1|UniProtKB=W5N2B8 W5N2B8 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009398.1|UniProtKB=W5MSV5 W5MSV5 PTHR23227:SF67 BUCENTAUR RELATED CRANIOFACIAL DEVELOPMENT PROTEIN 2-LIKE LEPOC|Ensembl=ENSLOCG00000001076.1|UniProtKB=W5LYK2 W5LYK2 PTHR24241:SF74 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ARGININE VASOPRESSIN RECEPTOR 2 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;response to organic substance#GO:0010033;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004928.1|UniProtKB=W5MC19 W5MC19 PTHR43157:SF44 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 13 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016686.1|UniProtKB=W5NJ08 W5NJ08 PTHR24034:SF140 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000006363.1|UniProtKB=W5MH35 W5MH35 MX1 PTHR11566:SF199 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MXC-RELATED pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 response to external biotic stimulus#GO:0043207;response to virus#GO:0009615;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;receptor internalization#GO:0031623;membrane organization#GO:0061024;transport#GO:0006810;synaptic vesicle recycling#GO:0036465;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;defense response to virus#GO:0051607;defense response#GO:0006952;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;defense response to symbiont#GO:0140546;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;vesicle budding from membrane#GO:0006900;defense response to other organism#GO:0098542;organelle organization#GO:0006996;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 supramolecular complex#GO:0099080;synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004716.1|UniProtKB=W5MBC0 W5MBC0 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000000837.1|UniProtKB=W5LXS8 W5LXS8 PTHR23227:SF67 BUCENTAUR RELATED CRANIOFACIAL DEVELOPMENT PROTEIN 2-LIKE LEPOC|Ensembl=ENSLOCG00000007082.1|UniProtKB=W5MJL4 W5MJL4 PTHR11639:SF130 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A11 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000007558.1|UniProtKB=W5MLC3 W5MLC3 TCERG1L PTHR15377:SF5 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1-LIKE PROTEIN molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;RNA polymerase binding#GO:0070063;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;enzyme binding#GO:0019899 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000002533.1|UniProtKB=W5M3L4 W5M3L4 PTHR46756:SF2 TRANSGELIN CALPONIN cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008086.1|UniProtKB=W5MN68 W5MN68 DXO PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007144.1|UniProtKB=W5MJT7 W5MJT7 PTHR19969:SF8 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Crk#P00933;CCKR signaling map#P06959>CRK#P07125;Angiogenesis#P00005>Crk#P00207 LEPOC|Ensembl=ENSLOCG00000012238.1|UniProtKB=W5N364 W5N364 PTHR11347:SF73 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;retina development in camera-type eye#GO:0060041;eye development#GO:0001654;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 LEPOC|Ensembl=ENSLOCG00000004149.1|UniProtKB=W5M9A3 W5M9A3 PTHR24406:SF8 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED FI01110P-RELATED nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012945.1|UniProtKB=W5N5P7 W5N5P7 UBR1 PTHR21497:SF27 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000203.1|UniProtKB=W5LVR9 W5LVR9 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004259.1|UniProtKB=W5M9N5 W5M9N5 PTHR35480:SF1 MATERNAL EFFECT EMBRYO ARREST 22 MATERNAL EFFECT EMBRYO ARREST 22 LEPOC|Ensembl=ENSLOCG00000009375.1|UniProtKB=W5MSS4 W5MSS4 PTHR11685:SF104 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144B ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;mitochondrial membrane#GO:0031966;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007857.1|UniProtKB=W5MMD8 W5MMD8 PTHR24092:SF50 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIB-RELATED ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;import into cell#GO:0098657;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011878.1|UniProtKB=W5N1U3 W5N1U3 PTHR24026:SF133 FAT ATYPICAL CADHERIN-RELATED CADHERIN-RELATED FAMILY MEMBER 2 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000008072.1|UniProtKB=W5MN44 W5MN44 PTHR22883:SF22 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC11-RELATED palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003591.1|UniProtKB=W5M797 W5M797 PTHR15268:SF17 THRAP3/BCLAF1 BCLAF1 AND THRAP3 FAMILY MEMBER 3 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006828.1|UniProtKB=W5MIP8 W5MIP8 PTHR16461:SF5 TOLL-INTERACTING PROTEIN TOLL-INTERACTING PROTEIN enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Toll receptor signaling pathway#P00054>Tollip#P01379 LEPOC|Ensembl=ENSLOCG00000004670.1|UniProtKB=W5MB37 W5MB37 UMODL1 PTHR24034:SF43 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488;transforming growth factor beta binding#GO:0050431;cytokine binding#GO:0019955 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000014483.1|UniProtKB=W5NB15 W5NB15 PTHR10015:SF336 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004092.1|UniProtKB=W5M925 W5M925 PTHR10075:SF103 BASIGIN RELATED ROUNDABOUT HOMOLOG 4 cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006041.1|UniProtKB=W5MFY5 W5MFY5 PTHR12011:SF285 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012811.1|UniProtKB=W5N554 W5N554 PTHR11824:SF17 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;neuromuscular junction development#GO:0007528;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 LEPOC|Ensembl=ENSLOCG00000013428.1|UniProtKB=W5N7I7 W5N7I7 PTHR10183:SF329 CALPAIN CALPAIN-3 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000009210.1|UniProtKB=W5MS71 W5MS71 PTHR11545:SF2 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005541.1|UniProtKB=W5ME84 W5ME84 PTHR10264:SF115 BAND 7 PROTEIN-RELATED STOMATIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010576.1|UniProtKB=W5MX48 W5MX48 PTHR12406:SF46 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;triglyceride catabolic process#GO:0019433;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000011675.1|UniProtKB=W5N137 W5N137 PTHR45752:SF196 LEUCINE-RICH REPEAT-CONTAINING GH17740P scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008260.1|UniProtKB=W5MNR8 W5MNR8 PTHR13502:SF4 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009366.1|UniProtKB=W5MSR3 W5MSR3 PTHR28032:SF1 FI02826P FI02826P proteasome binding#GO:0070628;protein-containing complex binding#GO:0044877;binding#GO:0005488 protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;response to topologically incorrect protein#GO:0035966;cellular response to stress#GO:0033554;protein-containing complex localization#GO:0031503 envelope#GO:0031975;nuclear membrane#GO:0031965;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012219.1|UniProtKB=W5N326 W5N326 PTHR43880:SF21 ALCOHOL DEHYDROGENASE S-(HYDROXYMETHYL)GLUTATHIONE DEHYDROGENASE cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;cellular process#GO:0009987;response to stimulus#GO:0050896;detoxification#GO:0098754;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016098.1|UniProtKB=W5NGS7 W5NGS7 PTHR48020:SF12 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001182.1|UniProtKB=W5LZ70 W5LZ70 MACF1 PTHR23169:SF25 ENVOPLAKIN MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1_2_3_4_5 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 regulation of cell-matrix adhesion#GO:0001952;regulation of microtubule-based process#GO:0032886;regulation of cellular component organization#GO:0051128;wound healing#GO:0042060;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell junction assembly#GO:1901888;regulation of cell adhesion#GO:0030155;intermediate filament cytoskeleton organization#GO:0045104;regulation of cell-substrate adhesion#GO:0010810;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000012857.1|UniProtKB=W5N5C8 W5N5C8 PTHR23406:SF27 MALIC ENZYME-RELATED NAD-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;dicarboxylic acid metabolic process#GO:0043648;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012861.1|UniProtKB=W5N5C7 W5N5C7 C5orf22 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 LEPOC|Ensembl=ENSLOCG00000012603.1|UniProtKB=W5N4G0 W5N4G0 ASPSCR1 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007267.1|UniProtKB=W5MK86 W5MK86 PTHR15856:SF26 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20-LIKE PROTEIN 1 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000000025.1|UniProtKB=W5LV72 W5LV72 PTHR24247:SF116 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000006214.1|UniProtKB=W5MGJ5 W5MGJ5 PTHR10285:SF66 URIDINE KINASE URIDINE-CYTIDINE KINASE 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 LEPOC|Ensembl=ENSLOCG00000009181.1|UniProtKB=W5MS44 W5MS44 PTHR23339:SF74 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;microtubule cytoskeleton organization#GO:0000226;positive regulation of cell cycle#GO:0045787;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell division#GO:0051302;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;positive regulation of cell division#GO:0051781;organelle assembly#GO:0070925;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;positive regulation of cell cycle process#GO:0090068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;organelle lumen#GO:0043233;cluster of actin-based cell projections#GO:0098862;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;kinocilium#GO:0060091;stereocilium bundle#GO:0032421;mitotic spindle#GO:0072686;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007514.1|UniProtKB=W5ML60 W5ML60 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 445 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000685.1|UniProtKB=W5LX98 W5LX98 PTHR23198:SF26 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP96 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012066.1|UniProtKB=W5N2I8 W5N2I8 PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004536.1|UniProtKB=W5MAL4 W5MAL4 PTHR10709:SF10 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Huntington disease#P00029>Arp2/3 complex#P00811 LEPOC|Ensembl=ENSLOCG00000004591.1|UniProtKB=W5MAT8 W5MAT8 PTHR12191:SF17 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP5 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013962.1|UniProtKB=W5N9A4 W5N9A4 PTHR11486:SF72 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 20 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000017418.1|UniProtKB=W5NLL4 W5NLL4 PTHR24247:SF34 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1F signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 LEPOC|Ensembl=ENSLOCG00000017706.1|UniProtKB=W5NMF2 W5NMF2 PTHR12871:SF5 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000016267.1|UniProtKB=W5NHF3 W5NHF3 PTHR28580:SF1 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000012027.1|UniProtKB=W5N2D2 W5N2D2 PTHR10984:SF36 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000000534.1|UniProtKB=W5LWT2 W5LWT2 PTHR25465:SF5 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003728.1|UniProtKB=W5M7U4 W5M7U4 PTHR15724:SF0 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000007057.1|UniProtKB=W5MJI0 W5MJI0 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000011618.1|UniProtKB=W5N0X7 W5N0X7 PTHR16705:SF9 COMPLEXIN COMPLEXIN-2 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;SNARE complex#GO:0031201;cell junction#GO:0030054;terminal bouton#GO:0043195;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000014608.1|UniProtKB=W5NBG5 W5NBG5 PTHR45834:SF6 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle assembly#GO:1902115;regulation of organelle organization#GO:0033043 cytoplasm#GO:0005737;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;cytosol#GO:0005829;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014062.1|UniProtKB=W5N9L9 W5N9L9 PTHR24330:SF5 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 1B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009574.1|UniProtKB=W5MTJ1 W5MTJ1 PNLIPRP2 PTHR11610:SF165 LIPASE PANCREATIC LIPASE-RELATED PROTEIN 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010113.1|UniProtKB=W5MVG5 W5MVG5 UBA3 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000005190.1|UniProtKB=W5MD08 W5MD08 PTHR45814:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1B N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;histone H3K4 methyltransferase activity#GO:0042800;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004102.1|UniProtKB=W5M950 W5M950 PTHR23167:SF39 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001150.1|UniProtKB=W5LZ04 W5LZ04 PTHR12546:SF44 FER-1-LIKE DYSFERLIN vesicle fusion#GO:0006906;negative regulation of biological process#GO:0048519;muscle cell differentiation#GO:0042692;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;macrophage activation#GO:0042116;regulation of cellular component organization#GO:0051128;wound healing#GO:0042060;regulation of vesicle-mediated transport#GO:0060627;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;macrophage activation involved in immune response#GO:0002281;regulation of transport#GO:0051049;establishment of localization#GO:0051234;vesicle organization#GO:0016050;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;leukocyte activation#GO:0045321;organelle fusion#GO:0048284;cellular developmental process#GO:0048869;regulation of endocytosis#GO:0030100;immune response#GO:0006955;vesicle-mediated transport#GO:0016192;negative regulation of transport#GO:0051051;cellular component organization#GO:0016043;cellular process#GO:0009987;cell activation involved in immune response#GO:0002263;myeloid leukocyte activation#GO:0002274;localization#GO:0051179;cell activation#GO:0001775;muscle cell development#GO:0055001;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;membrane fusion#GO:0061025;response to wounding#GO:0009611;leukocyte activation involved in immune response#GO:0002366;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of endocytosis#GO:0045806 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;sarcolemma#GO:0042383 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007258.1|UniProtKB=W5MK80 W5MK80 PHC3 PTHR12247:SF88 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017527.1|UniProtKB=W5NLX3 W5NLX3 PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of coagulation#GO:0050818;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of wound healing#GO:0061041;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;regulation of body fluid levels#GO:0050878;cell communication#GO:0007154;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of response to wounding#GO:1903034;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-1#P00404;Angiogenesis#P00005>PAR#P00192 LEPOC|Ensembl=ENSLOCG00000017543.1|UniProtKB=W5NLY9 W5NLY9 PTHR24410:SF5 HL07962P-RELATED ECTODERM-NEURAL CORTEX PROTEIN 1 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002434.1|UniProtKB=W5M3A0 W5M3A0 PTHR44145:SF3 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010854.1|UniProtKB=W5MY56 W5MY56 PTHR17271:SF12 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN ISOFORM X1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017798.1|UniProtKB=W5NMP3 W5NMP3 PTHR10614:SF7 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 2 protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Interleukin signaling pathway#P00036>IRS1/2#P00980;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 LEPOC|Ensembl=ENSLOCG00000013465.1|UniProtKB=W5N7J8 W5N7J8 PTHR28638:SF2 CELL CYCLE PROGRESSION PROTEIN 1 CELL CYCLE PROGRESSION PROTEIN 1 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002230.1|UniProtKB=W5M2I5 W5M2I5 PTHR11880:SF2 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005441.1|UniProtKB=W5MDU9 W5MDU9 PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 LEPOC|Ensembl=ENSLOCG00000000117.1|UniProtKB=W5LVH4 W5LVH4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003722.1|UniProtKB=W5M7T0 W5M7T0 PTHR11073:SF3 CALRETICULIN AND CALNEXIN CALRETICULIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;ERAD pathway#GO:0036503;cellular biosynthetic process#GO:0044249;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012451.1|UniProtKB=W5N3W8 W5N3W8 PTHR44229:SF5 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011945.1|UniProtKB=W5N231 W5N231 PTHR12375:SF52 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000001834.1|UniProtKB=W5M177 W5M177 PTHR11473:SF15 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;perikaryon#GO:0043204;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Dopamine receptor mediated signaling pathway#P05912>TH#P05970;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062 LEPOC|Ensembl=ENSLOCG00000004478.1|UniProtKB=W5MAF6 W5MAF6 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;transport#GO:0006810;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;vesicle-mediated transport#GO:0016192;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002755.1|UniProtKB=W5M4D4 W5M4D4 PTHR23147:SF231 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4.1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000981.1|UniProtKB=W5LYC1 W5LYC1 PTHR46881:SF1 PALMDELPHIN PALMDELPHIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013643.1|UniProtKB=W5N859 W5N859 PTHR45931:SF4 SI:CH211-59O9.10 E3 UBIQUITIN-PROTEIN LIGASE RLIM transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;heterochromatin formation#GO:0031507;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;negative regulation of biosynthetic process#GO:0009890;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007344.1|UniProtKB=W5MKJ4 W5MKJ4 PTHR46257:SF2 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007304.1|UniProtKB=W5MKD4 W5MKD4 PTHR10064:SF1 60S RIBOSOMAL PROTEIN L22 RIBOSOMAL PROTEIN EL22-LIKE structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011488.1|UniProtKB=W5N0F9 W5N0F9 PTHR21017:SF19 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 3B cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007224.1|UniProtKB=W5MK32 W5MK32 PTHR46771:SF2 DETERIN BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5.1 Angiogenesis#P00005>Survivin#P00198 LEPOC|Ensembl=ENSLOCG00000013518.1|UniProtKB=W5N7R0 W5N7R0 PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002976.1|UniProtKB=W5M547 W5M547 PTHR11937:SF175 ACTIN ACTIN-RELATED PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006112.1|UniProtKB=W5MG74 W5MG74 PTHR11256:SF12 BCL-2 RELATED BCL-2-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bcl-xS#P00323;Apoptosis signaling pathway#P00006>Bcl-xL#P00257;CCKR signaling map#P06959>BCL2L1#P07117 LEPOC|Ensembl=ENSLOCG00000006042.1|UniProtKB=W5MFY8 W5MFY8 PTHR46874:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;death receptor activity#GO:0005035;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;neuron apoptotic process#GO:0051402;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 p53 pathway#P00059>FAS#G01571;Apoptosis signaling pathway#P00006>FAS#P00289;FAS signaling pathway#P00020>Fas#P00612 LEPOC|Ensembl=ENSLOCG00000004488.1|UniProtKB=W5MAF5 W5MAF5 PTHR24278:SF38 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 4 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006933.1|UniProtKB=W5MJ25 W5MJ25 PTHR12015:SF190 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008989.1|UniProtKB=W5MRE5 W5MRE5 PTHR10153:SF43 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;calmodulin binding#GO:0005516;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;protein binding#GO:0005515;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000009456.1|UniProtKB=W5MT38 W5MT38 PTHR20955:SF1 PROTEIN JAGUNAL HOMOLOG 1 PROTEIN JAGUNAL HOMOLOG 1 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012548.1|UniProtKB=W5N493 W5N493 PTHR24201:SF7 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR D membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574;p53 pathway#P00059>ARF#P01482 LEPOC|Ensembl=ENSLOCG00000013904.1|UniProtKB=W5N941 W5N941 PTHR11616:SF124 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015853.1|UniProtKB=W5NFW0 W5NFW0 PTHR14513:SF0 PROTECTION OF TELOMERES 1 PROTECTION OF TELOMERES PROTEIN 1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded telomeric DNA binding#GO:0043047;molecular function regulator activity#GO:0098772;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092;DNA metabolic process#GO:0006259 nuclear telomere cap complex#GO:0000783;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002852.1|UniProtKB=W5M4P8 W5M4P8 PTHR15092:SF37 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 TARGET OF EGR1 PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;snRNA binding#GO:0017069;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000002864.1|UniProtKB=W5M4S1 W5M4S1 PTHR19957:SF334 SYNTAXIN SYNTAXIN-1B protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034;membrane traffic protein#PC00150 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000013871.1|UniProtKB=W5N915 W5N915 PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012117.1|UniProtKB=W5N2Q0 W5N2Q0 PTHR16509:SF1 FAMILY NOT NAMED MANGANESE-DEPENDENT ADP-RIBOSE_CDP-ALCOHOL DIPHOSPHATASE LEPOC|Ensembl=ENSLOCG00000014321.1|UniProtKB=W5NAH8 W5NAH8 PTHR43157:SF26 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE-LIKE glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006975.1|UniProtKB=W5MJ88 W5MJ88 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000006978.1|UniProtKB=W5MJ96 W5MJ96 PTHR23338:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011097.1|UniProtKB=W5MZ28 W5MZ28 PTHR24416:SF53 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR BETA signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;regulation of cell migration#GO:0030334;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;positive regulation of cell motility#GO:2000147;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;signaling#GO:0023052;chemotaxis#GO:0006935;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of cell motility#GO:2000145;blood vessel morphogenesis#GO:0048514;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell chemotaxis#GO:0060326;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cell migration#GO:0030335;positive regulation of phosphate metabolic process#GO:0045937;response to chemical#GO:0042221;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;blood vessel development#GO:0001568;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>PDGFR#P00230 LEPOC|Ensembl=ENSLOCG00000004640.1|UniProtKB=W5MAZ7 W5MAZ7 PTHR15617:SF1 TRANSCRIPTION FACTOR GIBBIN TRANSCRIPTION FACTOR GIBBIN LEPOC|Ensembl=ENSLOCG00000011513.1|UniProtKB=W5N0J1 W5N0J1 PTHR11377:SF7 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002238.1|UniProtKB=W5M2J6 W5M2J6 PTHR12682:SF11 ARCHEASE PROTEIN ARCHEASE LEPOC|Ensembl=ENSLOCG00000004753.1|UniProtKB=W5MBE1 W5MBE1 PTHR12398:SF20 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2 phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;molecular function inhibitor activity#GO:0140678;protein phosphatase inhibitor activity#GO:0004864;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of phosphoprotein phosphatase activity#GO:0043666;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 phosphatase modulator#PC00184;phosphatase inhibitor#PC00183 LEPOC|Ensembl=ENSLOCG00000011250.1|UniProtKB=W5MZL0 W5MZL0 PTHR10656:SF30 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 3 transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015430.1|UniProtKB=W5NED3 W5NED3 PTHR11905:SF32 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010482.1|UniProtKB=W5MWX6 W5MWX6 PTHR11908:SF129 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE_OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012071.1|UniProtKB=W5N2J3 W5N2J3 PTHR23239:SF32 INTERMEDIATE FILAMENT PHAKININ cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015116.1|UniProtKB=W5ND93 W5ND93 PTHR10984:SF30 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005563.1|UniProtKB=W5MEA6 W5MEA6 PTHR23343:SF31 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000016389.1|UniProtKB=W5NHY3 W5NHY3 MTARC2 PTHR14237:SF19 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1 LEPOC|Ensembl=ENSLOCG00000016735.1|UniProtKB=W5NJ75 W5NJ75 PTHR12431:SF16 SORTING NEXIN 17 AND 27 SORTING NEXIN-17 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005803.1|UniProtKB=W5MF51 W5MF51 RALGDS PTHR23113:SF35 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Ras Pathway#P04393>RalGDS#P04551 LEPOC|Ensembl=ENSLOCG00000000598.1|UniProtKB=W5LX00 W5LX00 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000006434.1|UniProtKB=W5MHB8 W5MHB8 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000004198.1|UniProtKB=W5M9F6 W5M9F6 PTHR46037:SF7 PROTEIN ENHANCER OF SEVENLESS 2B SLAP2 PROTEIN growth factor receptor binding#GO:0070851;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007467.1|UniProtKB=W5ML08 W5ML08 PTHR47194:SF3 SORTING NEXIN-29-RELATED SORTING NEXIN 29 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015628.1|UniProtKB=W5NF30 W5NF30 PTHR23117:SF18 GUANYLATE KINASE-RELATED LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011863.1|UniProtKB=W5N1T1 W5N1T1 PSIP1 PTHR12550:SF42 HEPATOMA-DERIVED GROWTH FACTOR-RELATED PC4 AND SFRS1-INTERACTING PROTEIN transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004341.1|UniProtKB=W5M9X2 W5M9X2 PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007016.1|UniProtKB=W5MJE1 W5MJE1 PTHR10658:SF28 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN ALPHA ISOFORM cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017338.1|UniProtKB=W5NLD4 W5NLD4 PTHR24203:SF75 ANKYRIN REPEAT FAMILY PROTEIN NOTCH-REGULATED ANKYRIN REPEAT-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004399.1|UniProtKB=W5MA63 W5MA63 PTHR13140:SF353 MYOSIN UNCONVENTIONAL MYOSIN-IH microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 actin filament-based movement#GO:0030048;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000016625.1|UniProtKB=W5NIS9 W5NIS9 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005847.1|UniProtKB=W5MFD8 W5MFD8 ST18 PTHR10816:SF9 MYELIN TRANSCRIPTION FACTOR 1-RELATED SUPPRESSION OF TUMORIGENICITY 18 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002803.1|UniProtKB=W5M4L7 W5M4L7 PTHR19307:SF12 TUMOR PROTEIN D52 TUMOR PROTEIN D52 cellular developmental process#GO:0048869;lymphocyte activation#GO:0046649;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;cellular process#GO:0009987;cell development#GO:0048468;cell activation#GO:0001775;immune system process#GO:0002376;B cell differentiation#GO:0030183;cell differentiation#GO:0030154;lymphocyte differentiation#GO:0030098;leukocyte differentiation#GO:0002521;anatomical structure development#GO:0048856;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;B cell activation#GO:0042113;leukocyte activation#GO:0045321 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016127.1|UniProtKB=W5NGW5 W5NGW5 PTHR24169:SF4 NUCLEAR FACTOR NF-KAPPA-B PROTEIN PROTO-ONCOGENE C-REL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;innate immune response#GO:0045087;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;canonical NF-kappaB signal transduction#GO:0007249;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;defense response to symbiont#GO:0140546;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;non-canonical NF-kappaB signal transduction#GO:0038061;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;defense response to other organism#GO:0098542;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 LEPOC|Ensembl=ENSLOCG00000003466.1|UniProtKB=W5M6V4 W5M6V4 PTHR31501:SF6 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004189.1|UniProtKB=W5M9E3 W5M9E3 PTHR45636:SF17 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000714.1|UniProtKB=W5LXD6 W5LXD6 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000156.1|UniProtKB=W5LVM5 W5LVM5 PTHR14187:SF5 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A LEPOC|Ensembl=ENSLOCG00000004278.1|UniProtKB=W5M9Q3 W5M9Q3 CDX2 PTHR24332:SF16 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009470.1|UniProtKB=W5MT63 W5MT63 PTHR47161:SF1 LYMPHOID-SPECIFIC HELICASE LYMPHOID-SPECIFIC HELICASE protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;DNA methylation#GO:0006306;protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;DNA modification#GO:0006304;heterochromatin formation#GO:0031507;DNA alkylation#GO:0006305;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;leukocyte proliferation#GO:0070661;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mononuclear cell proliferation#GO:0032943;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;lymphocyte activation#GO:0046649;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;lymphocyte proliferation#GO:0046651;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;primary metabolic process#GO:0044238;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;DNA methylation-dependent heterochromatin formation#GO:0006346;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;chromosome, centromeric region#GO:0000775;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000014092.1|UniProtKB=W5N9Q2 W5N9Q2 PTHR12650:SF15 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI RIBOSOMAL PROTEIN S30, ISOFORM A cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007372.1|UniProtKB=W5MKN3 W5MKN3 PTHR24072:SF23 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHO6 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 LEPOC|Ensembl=ENSLOCG00000005950.1|UniProtKB=W5MFN3 W5MFN3 PTHR13067:SF2 CASPASE-ACTIVATED DNASE CASPASE-ACTIVATED DNASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;nuclease activity#GO:0004518;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;execution phase of apoptosis#GO:0097194;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;cellular component disassembly#GO:0022411;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>CAD#P00618 LEPOC|Ensembl=ENSLOCG00000007074.1|UniProtKB=W5MJK2 W5MJK2 PTHR45771:SF5 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-D4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009593.1|UniProtKB=W5MTL1 W5MTL1 TMC1 PTHR23302:SF18 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 1 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of sound#GO:0007605;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;response to abiotic stimulus#GO:0009628;sensory perception of mechanical stimulus#GO:0050954 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011148.1|UniProtKB=W5MZ85 W5MZ85 PTHR17103:SF13 NEUREXOPHILIN NEUREXOPHILIN-1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001094.1|UniProtKB=W5LYS5 W5LYS5 PTHR10201:SF165 MATRIX METALLOPROTEINASE COLLAGENASE 3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Plasminogen activating cascade#P00050>MMP-13#P01250;Plasminogen activating cascade#P00050>pro-MMP-13#P01254;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000020987.1|UniProtKB=Q8HQM8 Q8HQM8 ATP 6 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE SUBUNIT A monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;ATPase complex#GO:1904949;cellular anatomical entity#GO:0110165;membrane#GO:0016020;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>ATP synthetase F0#P02797 LEPOC|Ensembl=ENSLOCG00000017068.1|UniProtKB=W5NKD4 W5NKD4 PTHR22957:SF601 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 30 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009073.1|UniProtKB=W5MRP9 W5MRP9 PTHR13367:SF8 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7B cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;protein K63-linked deubiquitination#GO:0070536;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018219.1|UniProtKB=W5NNW1 W5NNW1 PTHR15357:SF0 OLFACTORY MARKER PROTEIN OLFACTORY MARKER PROTEIN LEPOC|Ensembl=ENSLOCG00000002138.1|UniProtKB=W5M276 W5M276 PTHR22750:SF20 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003347.1|UniProtKB=W5M6E2 W5M6E2 PTHR24409:SF313 ZINC FINGER PROTEIN 142 C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007606.1|UniProtKB=W5MLH1 W5MLH1 ABI1 PTHR10460:SF2 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;SH3 domain binding#GO:0017124;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell motility#GO:0048870;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477 cytoplasm#GO:0005737;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;actin-based cell projection#GO:0098858;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002224.1|UniProtKB=W5M2I0 W5M2I0 PTHR31056:SF1 TRANSMEMBRANE PROTEIN 179B TRANSMEMBRANE PROTEIN 179B LEPOC|Ensembl=ENSLOCG00000002403.1|UniProtKB=W5M358 W5M358 PTHR11009:SF5 DER1-LIKE PROTEIN, DERLIN DERLIN-2 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001332.1|UniProtKB=W5LZK6 W5LZK6 PTHR11139:SF72 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE-PROTEIN KINASE ATM transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;telomere organization#GO:0032200;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;cell cycle checkpoint signaling#GO:0000075;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>ATM#P04669;p53 pathway#P00059>ATM/ATR#P01481 LEPOC|Ensembl=ENSLOCG00000001063.1|UniProtKB=W5LYJ3 W5LYJ3 TBL1XR1 PTHR22846:SF40 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1XR1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Ebi#P01453 LEPOC|Ensembl=ENSLOCG00000004135.1|UniProtKB=W5M982 W5M982 PTHR12902:SF7 WASP-1 ACTIN-BINDING PROTEIN WASF3 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 cell leading edge#GO:0031252;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008752.1|UniProtKB=W5MQK3 W5MQK3 PTHR24416:SF130 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 LEPOC|Ensembl=ENSLOCG00000002977.1|UniProtKB=W5M552 W5M552 PTHR21091:SF169 METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED UROPORPHYRINOGEN DECARBOXYLASE methyltransferase#PC00155 Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975 LEPOC|Ensembl=ENSLOCG00000014821.1|UniProtKB=W5NC93 W5NC93 PTHR15468:SF2 ZNF185 ZINC FINGER PROTEIN 185 LEPOC|Ensembl=ENSLOCG00000004034.1|UniProtKB=W5M8W2 W5M8W2 RSPH1 PTHR43215:SF14 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000013834.1|UniProtKB=W5N8V2 W5N8V2 PTHR28593:SF4 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013032.1|UniProtKB=W5N5Z2 W5N5Z2 FAM181A PTHR33766:SF1 PROTEIN FAM181B PROTEIN FAM181A LEPOC|Ensembl=ENSLOCG00000006192.1|UniProtKB=W5MGL3 W5MGL3 PTHR24023:SF539 COLLAGEN ALPHA COLLAGEN ALPHA-2(V) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;supramolecular fiber#GO:0099512 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000015815.1|UniProtKB=W5NFR1 W5NFR1 PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007206.1|UniProtKB=W5MK09 W5MK09 PTHR10845:SF184 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 4 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 LEPOC|Ensembl=ENSLOCG00000005925.1|UniProtKB=W5MFK1 W5MFK1 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012157.1|UniProtKB=W5N2V6 W5N2V6 PTHR45796:SF7 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P4 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000002437.1|UniProtKB=W5M399 W5M399 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006592.1|UniProtKB=W5MHV4 W5MHV4 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002546.1|UniProtKB=W5M3P7 W5M3P7 PTHR12634:SF12 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 3 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of phosphoprotein phosphatase activity#GO:0043666;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000010901.1|UniProtKB=W5MYB8 W5MYB8 PTHR10132:SF17 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER EPSILON-SARCOGLYCAN membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000005665.1|UniProtKB=W5MEM8 W5MEM8 PTHR28640:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000016674.1|UniProtKB=W5NIY9 W5NIY9 PTHR10177:SF66 CYCLINS G1_S-SPECIFIC CYCLIN-D2 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 PI3 kinase pathway#P00048>Cyclin d#G01546;Cell cycle#P00013>Cyclin D#P00484 LEPOC|Ensembl=ENSLOCG00000015229.1|UniProtKB=W5NDN2 W5NDN2 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000006981.1|UniProtKB=W5MJA2 W5MJA2 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000011129.1|UniProtKB=W5MZ69 W5MZ69 PTHR24055:SF110 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 14 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>p38#P01352;p38 MAPK pathway#P05918>p38alpha#P06031;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>p38#P00562;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Parkinson disease#P00049>p38 MAPK#P01212;Oxidative stress response#P00046>p38#P01135;FGF signaling pathway#P00021>p38#P00644;CCKR signaling map#P06959>p38MAPK#P07079;CCKR signaling map#P06959>MAPKAP-K2#P07217;VEGF signaling pathway#P00056>p38MAPK#P01423;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;JAK/STAT signaling pathway#P00038>Serine kinase#P01029;TGF-beta signaling pathway#P00052>P38#P01275;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Angiogenesis#P00005>p38MAPK#P00182;Ras Pathway#P04393>p38#P04558;B cell activation#P00010>p38#P00384 LEPOC|Ensembl=ENSLOCG00000007941.1|UniProtKB=W5MMP4 W5MMP4 PTHR11573:SF6 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 LEPOC|Ensembl=ENSLOCG00000004734.1|UniProtKB=W5MBB4 W5MBB4 PTHR46282:SF2 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN pigmentation#GO:0043473;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000017704.1|UniProtKB=W5NMF0 W5NMF0 PTHR16081:SF0 VERTNIN VERTNIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002298.1|UniProtKB=W5M2S8 W5M2S8 PTHR17598:SF13 DNA POLYMERASE DELTA SUBUNIT 3 DNA POLYMERASE DELTA SUBUNIT 3 DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to light stimulus#GO:0071482;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;response to UV#GO:0009411;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear replication fork#GO:0043596;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010314.1|UniProtKB=W5MW81 W5MW81 PTHR12607:SF11 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;beta-catenin binding#GO:0008013 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;regulation of signal transduction#GO:0009966;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cellular component organization#GO:0051129;pattern specification process#GO:0007389;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;cell motility#GO:0048870;regulation of protein-containing complex disassembly#GO:0043244;cell fate commitment#GO:0045165;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of supramolecular fiber organization#GO:1902904;regulation of response to stimulus#GO:0048583;regulation of supramolecular fiber organization#GO:1902903;regulation of protein depolymerization#GO:1901879;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell migration#GO:0016477;negative regulation of cytoskeleton organization#GO:0051494 supramolecular complex#GO:0099080;membrane protein complex#GO:0098796;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 LEPOC|Ensembl=ENSLOCG00000009635.1|UniProtKB=W5MTS6 W5MTS6 PTHR21686:SF12 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002657.1|UniProtKB=W5M443 W5M443 PTHR22928:SF3 TELOMERE-ASSOCIATED PROTEIN RIF1 TELOMERE-ASSOCIATED PROTEIN RIF1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;telomere organization#GO:0032200;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;chromosome organization#GO:0051276;organelle organization#GO:0006996;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007285.1|UniProtKB=W5MKA9 W5MKA9 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015902.1|UniProtKB=W5NG23 W5NG23 PTHR23236:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H RNA-BINDING PROTEIN 34 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000017750.1|UniProtKB=W5NMJ5 W5NMJ5 PIRT PTHR16100:SF4 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER PHOSPHOINOSITIDE-INTERACTING PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;transmembrane transporter binding#GO:0044325;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;positive regulation of molecular function#GO:0044093;regulation of localization#GO:0032879;positive regulation of transport#GO:0051050;positive regulation of cation channel activity#GO:2001259;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of transporter activity#GO:0032411;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017696.1|UniProtKB=W5NME2 W5NME2 BDKRB2 PTHR24228:SF25 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B2 BRADYKININ RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000005140.1|UniProtKB=W5MCS8 W5MCS8 PTHR15326:SF9 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012967.1|UniProtKB=W5N5R1 W5N5R1 PTHR11461:SF180 SERINE PROTEASE INHIBITOR, SERPIN LEUKOCYTE ELASTASE INHIBITOR peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000006875.1|UniProtKB=W5MIW1 W5MIW1 PTHR24112:SF32 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2_3 AND MYOSIN-I LINKER PROTEIN 2 regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell leading edge#GO:0031252;lamellipodium#GO:0030027;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001910.1|UniProtKB=W5M1G1 W5M1G1 PTHR24111:SF4 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000012077.1|UniProtKB=W5N2K1 W5N2K1 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208 LEPOC|Ensembl=ENSLOCG00000007272.1|UniProtKB=W5MK93 W5MK93 PTHR15564:SF10 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 ISOFORM X1 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of cell cycle#GO:0045786;developmental process#GO:0032502;multicellular organism development#GO:0007275;response to lipid#GO:0033993;negative regulation of mitotic cell cycle#GO:0045930;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;dendrite#GO:0030425;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008382.1|UniProtKB=W5MP77 W5MP77 NEFH PTHR23214:SF1 NEUROFILAMENT TRIPLET H PROTEIN NEUROFILAMENT HEAVY POLYPEPTIDE LEPOC|Ensembl=ENSLOCG00000013864.1|UniProtKB=W5N8Y8 W5N8Y8 PTHR48029:SF1 NUCLEOLAR PROTEIN 8 NUCLEOLAR PROTEIN 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 LEPOC|Ensembl=ENSLOCG00000013072.1|UniProtKB=W5N641 W5N641 PTHR18945:SF912 NEUROTRANSMITTER GATED ION CHANNEL ZINC-ACTIVATED LIGAND-GATED ION CHANNEL monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013829.1|UniProtKB=W5N8U1 W5N8U1 PTHR31997:SF2 AGAP003710-PA PROTEIN FAM149A LEPOC|Ensembl=ENSLOCG00000005361.1|UniProtKB=W5MDP0 W5MDP0 PTHR12027:SF89 WNT RELATED PROTEIN WNT-10A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000007121.1|UniProtKB=W5MJT8 W5MJT8 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005990.1|UniProtKB=W5MFT7 W5MFT7 PTHR12345:SF17 SYNTENIN RELATED SDCBP PROTEIN cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016650.1|UniProtKB=W5NIV7 W5NIV7 PTHR21608:SF8 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26B LEPOC|Ensembl=ENSLOCG00000010234.1|UniProtKB=W5MVX3 W5MVX3 PTHR11183:SF167 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-2 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014620.1|UniProtKB=W5NBI5 W5NBI5 PTHR35256:SF1 CHROMOSOME 8 OPEN READING FRAME 48 EXPRESSED SEQUENCE AI429214 LEPOC|Ensembl=ENSLOCG00000004914.1|UniProtKB=W5MC58 W5MC58 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003158.1|UniProtKB=W5M5R6 W5M5R6 PTHR10378:SF8 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000017327.1|UniProtKB=W5NLC3 W5NLC3 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005784.1|UniProtKB=W5MF30 W5MF30 MAST2 PTHR24356:SF136 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002135.1|UniProtKB=W5M283 W5M283 PTHR34930:SF5 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000011837.1|UniProtKB=W5N1Q4 W5N1Q4 PTHR31859:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39B LEPOC|Ensembl=ENSLOCG00000018105.1|UniProtKB=W5NNJ7 W5NNJ7 PTHR10155:SF4 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 JAK/STAT signaling pathway#P00038>SOCS#P01030 LEPOC|Ensembl=ENSLOCG00000015705.1|UniProtKB=W5NFC4 W5NFC4 C1orf198 PTHR34394:SF1 SIMILAR TO RIKEN CDNA 2310022B05 SIMILAR TO RIKEN CDNA 2310022B05 LEPOC|Ensembl=ENSLOCG00000004450.1|UniProtKB=W5MAB1 W5MAB1 PTHR13199:SF12 GH03947P ATOS HOMOLOG PROTEIN B LEPOC|Ensembl=ENSLOCG00000000550.1|UniProtKB=W5LWV0 W5LWV0 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000007896.1|UniProtKB=W5MMI2 W5MMI2 SPEN PTHR23189:SF48 RNA RECOGNITION MOTIF-CONTAINING MSX2-INTERACTING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009336.1|UniProtKB=W5MSP5 W5MSP5 PTHR24023:SF714 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;kidney development#GO:0001822;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000010553.1|UniProtKB=W5MX25 W5MX25 ERG28 PTHR15451:SF19 ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009847.1|UniProtKB=W5MUI1 W5MUI1 PTHR22988:SF34 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012277.1|UniProtKB=W5N397 W5N397 PTHR12027:SF84 WNT RELATED PROTEIN WNT-9B molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000015546.1|UniProtKB=W5NET3 W5NET3 CLHC1 PTHR10292:SF11 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN LINKER DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;membrane coat#GO:0030117;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000001323.1|UniProtKB=W5LZE6 W5LZE6 PTHR15315:SF112 RING FINGER PROTEIN 41, 151 PDZ DOMAIN CONTAINING RING FINGER 3 LEPOC|Ensembl=ENSLOCG00000001736.1|UniProtKB=W5M0U8 W5M0U8 PTHR11984:SF39 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000010952.1|UniProtKB=W5MYI3 W5MYI3 PTHR45689:SF8 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 2-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;regulation of membrane depolarization#GO:0003254;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005434.1|UniProtKB=W5MDV0 W5MDV0 PTHR24115:SF408 KINESIN-RELATED KINESIN-LIKE PROTEIN pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004650.1|UniProtKB=W5MB12 W5MB12 ACSF3 PTHR24096:SF267 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000002912.1|UniProtKB=W5M4Z2 W5M4Z2 SIDT1 PTHR12185:SF15 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transmembrane transporter activity#GO:0022857;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleobase-containing compound transmembrane transporter activity#GO:0015932;double-stranded RNA binding#GO:0003725;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;RNA localization#GO:0006403 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007068.1|UniProtKB=W5MJJ7 W5MJJ7 PTHR13924:SF4 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3 head development#GO:0060322;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;animal organ development#GO:0048513;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;brain development#GO:0007420;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;forebrain development#GO:0030900;system development#GO:0048731;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005778.1|UniProtKB=W5MF20 W5MF20 PTHR11259:SF6 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN C GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013556.1|UniProtKB=W5N7V4 W5N7V4 GALNTL6 PTHR11675:SF129 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE-LIKE 6 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005362.1|UniProtKB=W5MDK4 W5MDK4 PTHR12357:SF8 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 2 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of mRNA metabolic process#GO:1903313;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;mRNA destabilization#GO:0061157;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002674.1|UniProtKB=W5M477 W5M477 PTHR11616:SF263 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005205.1|UniProtKB=W5MD05 W5MD05 PTHR32178:SF8 FAM187 PROTEIN FAM187B immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000008009.1|UniProtKB=W5MMX2 W5MMX2 PTHR10229:SF0 GTP-BINDING PROTEIN HFLX GTP-BINDING PROTEIN 6-RELATED ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016934.1|UniProtKB=W5NJX3 W5NJX3 PTHR13293:SF8 AKIRIN-RELATED AKIRIN-2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;regulation of DNA-templated transcription#GO:0006355;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002584.1|UniProtKB=W5M3T0 W5M3T0 GAN PTHR24412:SF232 KELCH PROTEIN GIGAXONIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007198.1|UniProtKB=W5MK20 W5MK20 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008248.1|UniProtKB=W5MNQ2 W5MNQ2 PTHR45864:SF4 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 3 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 LEPOC|Ensembl=ENSLOCG00000002163.1|UniProtKB=W5M2A8 W5M2A8 PTHR10219:SF20 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001815.1|UniProtKB=W5M136 W5M136 PTHR31501:SF5 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013830.1|UniProtKB=W5N8U6 W5N8U6 PTHR24103:SF668 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN_ISG15 LIGASE TRIM25 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014296.1|UniProtKB=W5NAE1 W5NAE1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010824.1|UniProtKB=W5MY11 W5MY11 PTHR11100:SF7 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-1, MEMBRANE-BOUND ISOFORM protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;signaling receptor binding#GO:0005102;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;protein-containing complex assembly#GO:0065003;activation of protein kinase activity#GO:0032147;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000007634.1|UniProtKB=W5MLK6 W5MLK6 PTHR23255:SF22 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Gonadotropin-releasing hormone receptor pathway#P06664>Alk4#P06845 LEPOC|Ensembl=ENSLOCG00000001468.1|UniProtKB=W5M029 W5M029 KIF5C PTHR24115:SF380 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5C cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515 neuron projection guidance#GO:0097485;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;synaptic vesicle transport#GO:0048489;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;microtubule-based transport#GO:0099111;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;generation of neurons#GO:0048699;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004715.1|UniProtKB=W5MB89 W5MB89 PTHR12317:SF74 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000017465.1|UniProtKB=W5NLR1 W5NLR1 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007240.1|UniProtKB=W5MK53 W5MK53 PTHR10657:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017868.1|UniProtKB=W5NMW2 W5NMW2 PTHR26451:SF869 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 530-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014795.1|UniProtKB=W5NC60 W5NC60 PTHR32003:SF1 PROTEIN FAM199X PROTEIN FAM199X LEPOC|Ensembl=ENSLOCG00000010534.1|UniProtKB=W5MWZ4 W5MWZ4 PTHR44068:SF1 ZGC:194242 HYPOTHETICAL LOC100005854 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008038.1|UniProtKB=W5MN03 W5MN03 PTHR24355:SF12 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK7 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 LEPOC|Ensembl=ENSLOCG00000015723.1|UniProtKB=W5NFE7 W5NFE7 PTHR21308:SF1 PHYTANOYL-COA ALPHA-HYDROXYLASE PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000001849.1|UniProtKB=W5M186 W5M186 PTHR12555:SF13 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000007698.1|UniProtKB=W5MLU8 W5MLU8 PTHR23426:SF65 FERREDOXIN/ADRENODOXIN FERREDOXIN-2, MITOCHONDRIAL cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 LEPOC|Ensembl=ENSLOCG00000009418.1|UniProtKB=W5MSY1 W5MSY1 PTHR12297:SF3 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008562.1|UniProtKB=W5MPV3 W5MPV3 PTHR13077:SF7 SELENOPROTEIN F SELENOPROTEIN M oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001378.1|UniProtKB=W5LZK3 W5LZK3 PTHR10225:SF6 HYALURONAN RECEPTOR CD44 ANTIGEN carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of ERK1 and ERK2 cascade#GO:0070374;defense response#GO:0006952;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 basal plasma membrane#GO:0009925;receptor complex#GO:0043235;protein-containing complex#GO:0032991;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>CD44 intracellular fragment#P00121;Alzheimer disease-presenilin pathway#P00004>CD44 N-terminal fragment#P00174;Alzheimer disease-presenilin pathway#P00004>CD44#P00145;Alzheimer disease-presenilin pathway#P00004>CD44 C-terminal fragment#P00123;Alzheimer disease-presenilin pathway#P00004>CD44 transmembrane fragment#P00167 LEPOC|Ensembl=ENSLOCG00000008996.1|UniProtKB=W5MRF2 W5MRF2 PTHR45960:SF5 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000015774.1|UniProtKB=W5NFL1 W5NFL1 PTHR18934:SF145 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX57-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000007435.1|UniProtKB=W5MKW4 W5MKW4 PTHR13266:SF1 PROTEASOME INHIBITOR PROTEASOME INHIBITOR PI31 SUBUNIT macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000017073.1|UniProtKB=W5NKE1 W5NKE1 PTHR22951:SF4 CLATHRIN ASSEMBLY PROTEIN CLATHRIN COAT ASSEMBLY PROTEIN AP180 phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;establishment of organelle localization#GO:0051656;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000010775.1|UniProtKB=W5MXU1 W5MXU1 PTHR38490:SF1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002631.1|UniProtKB=W5M408 W5M408 PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000014433.1|UniProtKB=W5NAV8 W5NAV8 PTHR12635:SF13 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 6 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009854.1|UniProtKB=W5MUI6 W5MUI6 PTHR14987:SF3 PROTEIN LBH-RELATED LBH DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000001522.1|UniProtKB=W5M044 W5M044 PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010869.1|UniProtKB=W5MY62 W5MY62 PTHR11889:SF39 HEDGEHOG INDIAN HEDGEHOG PROTEIN cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;developmental process#GO:0032502;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000798.1|UniProtKB=W5LXN2 W5LXN2 PTHR22957:SF360 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 17 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003692.1|UniProtKB=W5M7N1 W5M7N1 PTHR21093:SF3 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1B LEPOC|Ensembl=ENSLOCG00000002548.1|UniProtKB=W5M3N9 W5M3N9 APBA3 PTHR12345:SF9 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 3 amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 LEPOC|Ensembl=ENSLOCG00000007105.1|UniProtKB=W5MJP3 W5MJP3 PTHR11211:SF17 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010353.1|UniProtKB=W5MWC8 W5MWC8 PTHR11537:SF182 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic membrane#GO:0045211;neuronal cell body#GO:0043025;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000018136.1|UniProtKB=W5NNM8 W5NNM8 OPN4 PTHR24240:SF72 OPSIN MELANOPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009428.1|UniProtKB=W5MSZ8 W5MSZ8 PTHR12654:SF0 BILE ACID BETA-GLUCOSIDASE-RELATED NON-LYSOSOMAL GLUCOSYLCERAMIDASE glucosidase#PC00108;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007388.1|UniProtKB=W5MKQ6 W5MKQ6 PTHR46026:SF4 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F PH DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;cellular component organization#GO:0016043;plasma membrane bounded cell projection assembly#GO:0120031;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cell leading edge#GO:0031252;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002702.1|UniProtKB=W5M467 W5M467 PTHR13180:SF0 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A endosomal transport#GO:0016197;establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;late endosome to vacuole transport#GO:0045324;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 LEPOC|Ensembl=ENSLOCG00000013198.1|UniProtKB=W5N6K7 W5N6K7 PTHR33862:SF3 OROFACIAL CLEFT 1 CANDIDATE GENE 1 PROTEIN OROFACIAL CLEFT 1 CANDIDATE GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000012584.1|UniProtKB=W5N4D1 W5N4D1 CAAP1 PTHR14740:SF3 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of apoptotic signaling pathway#GO:2001233;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of apoptotic process#GO:0043066;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 LEPOC|Ensembl=ENSLOCG00000011552.1|UniProtKB=W5N0N6 W5N0N6 PTHR32510:SF3 TRANSMEMBRANE PROTEIN 98 TRANSMEMBRANE PROTEIN 98 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007115.1|UniProtKB=W5MJQ3 W5MJQ3 PTHR21562:SF10 NOTUM-RELATED CARBOXYLESTERASE NOTUM2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;lipoprotein metabolic process#GO:0042157 LEPOC|Ensembl=ENSLOCG00000006774.1|UniProtKB=W5MIH4 W5MIH4 PTHR11324:SF16 IL16-RELATED PDZ DOMAIN-CONTAINING PROTEIN 2 cytokine#PC00083;interleukin superfamily#PC00128 LEPOC|Ensembl=ENSLOCG00000010053.1|UniProtKB=W5MV94 W5MV94 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015883.1|UniProtKB=W5NG01 W5NG01 PTHR24304:SF2 CYTOCHROME P450 FAMILY 7 24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001297.1|UniProtKB=W5LZB3 W5LZB3 PTHR35543:SF1 PROTEIN C11ORF74 INTRAFLAGELLAR TRANSPORT-ASSOCIATED PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;fertilization#GO:0009566;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609;acrosome reaction#GO:0007340 9+0 non-motile cilium#GO:0097731;cytoplasm#GO:0005737;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005941.1|UniProtKB=W5MFL8 W5MFL8 PTHR14360:SF14 PROTEIN FMP32, MITOCHONDRIAL COILED-COIL DOMAIN-CONTAINING PROTEIN 90B, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005556.1|UniProtKB=W5ME98 W5ME98 PTHR28650:SF1 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN LEPOC|Ensembl=ENSLOCG00000005176.1|UniProtKB=W5MCX4 W5MCX4 PTHR10915:SF7 SYNDECAN SYNDECAN-3 cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015415.1|UniProtKB=W5NEB5 W5NEB5 PTHR11347:SF104 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000001091.1|UniProtKB=W5LYM4 W5LYM4 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003787.1|UniProtKB=W5M808 W5M808 PTHR24124:SF7 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR DELTA regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003446.1|UniProtKB=W5M6U6 W5M6U6 PTHR13064:SF2 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9B positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000013974.1|UniProtKB=W5N9C6 W5N9C6 PTHR23257:SF763 SERINE-THREONINE PROTEIN KINASE RAF PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016784.1|UniProtKB=W5NJE2 W5NJE2 PTHR11782:SF99 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;nucleotide phosphatase#PC00173;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004101.1|UniProtKB=W5M943 W5M943 PTHR23504:SF34 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003620.1|UniProtKB=W5M7D5 W5M7D5 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010778.1|UniProtKB=W5MXU5 W5MXU5 PTHR10454:SF240 CASPASE CASPASE 20, APOPTOSIS-RELATED CYSTEINE PEPTIDASE-RELATED cysteine-type peptidase activity#GO:0008234;binding#GO:0005488;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;protein binding#GO:0005515;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase8#P00594;Apoptosis signaling pathway#P00006>Caspase 8#P00299;Huntington disease#P00029>Pro-caspase 8#P00767;FAS signaling pathway#P00020>Pro-Caspase8#P00604;Huntington disease#P00029>Caspase 8#P00808 LEPOC|Ensembl=ENSLOCG00000015810.1|UniProtKB=W5NFQ3 W5NFQ3 PTHR24392:SF40 ZINC FINGER PROTEIN ZINC FINGER Y-CHROMOSOMAL PROTEIN 1 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007666.1|UniProtKB=W5MLQ7 W5MLQ7 ARAP1 PTHR45899:SF3 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004634.1|UniProtKB=W5MAZ5 W5MAZ5 PTHR12736:SF5 LANC-LIKE PROTEIN GLUTATHIONE S-TRANSFERASE LANCL1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013664.1|UniProtKB=W5N895 W5N895 PTHR45976:SF3 ARMADILLO SEGMENT POLARITY PROTEIN JUNCTION PLAKOGLOBIN phosphatase binding#GO:0019902;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;cell adhesion molecule binding#GO:0050839;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;plasma membrane#GO:0005886 Alzheimer disease-presenilin pathway#P00004>gammacatenin#P00153 LEPOC|Ensembl=ENSLOCG00000011073.1|UniProtKB=W5MYY5 W5MYY5 PTHR22883:SF213 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC22 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010278.1|UniProtKB=W5MW25 W5MW25 PTHR14491:SF4 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHC LEPOC|Ensembl=ENSLOCG00000002503.1|UniProtKB=W5M3I1 W5M3I1 MAP3K11 PTHR23257:SF757 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005426.1|UniProtKB=W5MDT5 W5MDT5 PTHR11751:SF311 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 2 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015601.1|UniProtKB=W5NEZ9 W5NEZ9 PTHR11909:SF297 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;peptidyl-tyrosine modification#GO:0018212;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013223.1|UniProtKB=W5N6N5 W5N6N5 PTHR31784:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000010037.1|UniProtKB=W5MV80 W5MV80 EVC2 PTHR16795:SF14 LIMBIN/ELLIS-VAN CREVELD PROTEIN LIMBIN bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ciliary membrane#GO:0060170;plasma membrane protein complex#GO:0098797;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002422.1|UniProtKB=W5M385 W5M385 PTHR23235:SF155 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE 4-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008326.1|UniProtKB=W5MP08 W5MP08 PTHR42904:SF1 NUDIX HYDROLASE, NUDC SUBFAMILY NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 17 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009567.1|UniProtKB=W5MTI2 W5MTI2 PTHR16514:SF4 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 4 SMAD binding#GO:0046332;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;Golgi membrane#GO:0000139 LEPOC|Ensembl=ENSLOCG00000017838.1|UniProtKB=W5NMT2 W5NMT2 PTHR45617:SF168 LEUCINE RICH REPEAT FAMILY PROTEIN RETICULON 4 RECEPTOR LIKE 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001892.1|UniProtKB=W5M1D7 W5M1D7 PTHR23352:SF2 NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEIN NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011930.1|UniProtKB=W5N220 W5N220 PTHR12582:SF4 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000005938.1|UniProtKB=W5MFL7 W5MFL7 PTHR45718:SF2 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLI1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cell communication#GO:0007154;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 LEPOC|Ensembl=ENSLOCG00000008955.1|UniProtKB=W5MR99 W5MR99 CCDC112 PTHR21549:SF0 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 112 LEPOC|Ensembl=ENSLOCG00000011089.1|UniProtKB=W5MZ12 W5MZ12 PTHR34340:SF3 MELANOREGULIN MELANOREGULIN cellular developmental process#GO:0048869;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;developmental process#GO:0032502;pigmentation#GO:0043473;cellular process#GO:0009987;localization#GO:0051179;cell differentiation#GO:0030154;developmental pigmentation#GO:0048066;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;melanocyte differentiation#GO:0030318;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013866.1|UniProtKB=W5N8Z9 W5N8Z9 PTHR22762:SF92 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lysosome organization#GO:0007040;glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;polysaccharide metabolic process#GO:0005976;vacuole organization#GO:0007033;organelle organization#GO:0006996;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lytic vacuole organization#GO:0080171;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007556.1|UniProtKB=W5MLB2 W5MLB2 PTHR13196:SF24 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1B lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000010788.1|UniProtKB=W5MXV7 W5MXV7 PTHR19325:SF570 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT COMPONENT 4 BINDING PROTEIN, MEMBRANE complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000001618.1|UniProtKB=W5M0F8 W5M0F8 PTHR32123:SF12 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 1 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008333.1|UniProtKB=W5MP14 W5MP14 PTHR47708:SF2 FAMILY NOT NAMED SI:CH73-132F6.5 LEPOC|Ensembl=ENSLOCG00000009271.1|UniProtKB=W5MSF1 W5MSF1 PTHR12276:SF45 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002130.1|UniProtKB=W5M280 W5M280 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013897.1|UniProtKB=W5N932 W5N932 PTHR13703:SF53 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;activin receptor signaling pathway#GO:0032924;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 LEPOC|Ensembl=ENSLOCG00000006950.1|UniProtKB=W5MJ50 W5MJ50 PTHR28646:SF1 TRANSMEMBRANE PROTEIN 201 TRANSMEMBRANE PROTEIN 201 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656 envelope#GO:0031975;nuclear membrane#GO:0031965;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015014.1|UniProtKB=W5NCX4 W5NCX4 PTHR23087:SF10 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOMAL-BINDING DOMAIN 7-RELATED protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013547.1|UniProtKB=W5N7V2 W5N7V2 PTHR46349:SF2 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN-LIKE PROTEIN 1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to cell junction#GO:1902414;protein localization#GO:0008104 cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000012175.1|UniProtKB=W5N2W7 W5N2W7 PTHR10127:SF814 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT BETA hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017935.1|UniProtKB=W5NN29 W5NN29 PTHR24062:SF158 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006254.1|UniProtKB=W5MGP7 W5MGP7 PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C_D nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012477.1|UniProtKB=W5N404 W5N404 PTHR14991:SF0 RING FINGER PROTEIN 32 RING FINGER PROTEIN 32 LEPOC|Ensembl=ENSLOCG00000004596.1|UniProtKB=W5MAU5 W5MAU5 PTHR15467:SF6 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011626.1|UniProtKB=W5N0Y0 W5N0Y0 YY1 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY YY2 TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016075.1|UniProtKB=W5NGQ0 W5NGQ0 PTHR23167:SF43 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007022.1|UniProtKB=W5MJE4 W5MJE4 PTHR21595:SF2 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein depolymerization#GO:1901879;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016645.1|UniProtKB=W5NIV1 W5NIV1 PTHR28581:SF1 CONSORTIN CONSORTIN protein binding#GO:0005515;binding#GO:0005488 positive regulation of establishment of protein localization#GO:1904951;regulation of protein localization to membrane#GO:1905475;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of protein transport#GO:0051222;positive regulation of protein localization#GO:1903829;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009856.1|UniProtKB=W5MUJ1 W5MUJ1 PTHR12195:SF5 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nervous system development#GO:0007399;positive regulation of proteolysis#GO:0045862;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;zymogen activation#GO:0031638;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of translation#GO:0006417;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;regulation of amide metabolic process#GO:0034248;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;protein processing#GO:0016485;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;regulation of biosynthetic process#GO:0009889;cell death#GO:0008219;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule biosynthetic process#GO:0009059;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cell projection assembly#GO:0030031;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;generation of neurons#GO:0048699 cytoplasm#GO:0005737;synapse#GO:0045202;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 LEPOC|Ensembl=ENSLOCG00000003099.1|UniProtKB=W5M5J9 W5M5J9 PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014876.1|UniProtKB=W5NCG4 W5NCG4 PTHR47992:SF217 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010870.1|UniProtKB=W5MY59 W5MY59 PTHR14768:SF4 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1-LIKE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006927.1|UniProtKB=W5MJ27 W5MJ27 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006839.1|UniProtKB=W5MIR0 W5MIR0 PTHR14102:SF9 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG ALPHA establishment or maintenance of cell polarity#GO:0007163;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular anatomical structure#GO:0005622 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000010229.1|UniProtKB=W5MVW7 W5MVW7 PTHR46815:SF1 PROTEIN KISH-B PROTEIN KISH-B LEPOC|Ensembl=ENSLOCG00000016786.1|UniProtKB=W5NJE0 W5NJE0 PTHR11216:SF67 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;plasma membrane bounded cell projection organization#GO:0120036;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization#GO:0008104;organelle assembly#GO:0070925;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018025.1|UniProtKB=W5NNB7 W5NNB7 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012919.1|UniProtKB=W5N5J9 W5N5J9 PTHR21608:SF6 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26A LEPOC|Ensembl=ENSLOCG00000001459.1|UniProtKB=W5LZX1 W5LZX1 PTHR46571:SF1 SORTING NEXIN-8 SORTING NEXIN-8 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009988.1|UniProtKB=W5MV07 W5MV07 PTHR20930:SF0 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN LEPOC|Ensembl=ENSLOCG00000017166.1|UniProtKB=W5NKQ9 W5NKQ9 PTHR14965:SF2 SI:CH73-248E21.1 BCL-2-LIKE PROTEIN 12 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of apoptotic signaling pathway#GO:2001233;regulation of programmed cell death#GO:0043067 LEPOC|Ensembl=ENSLOCG00000002259.1|UniProtKB=W5M2M8 W5M2M8 PTHR12929:SF4 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3 transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009064.1|UniProtKB=W5MRN3 W5MRN3 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008741.1|UniProtKB=W5MQI6 W5MQI6 HHIPL1 PTHR19328:SF32 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012634.1|UniProtKB=W5N4K2 W5N4K2 PTHR23302:SF4 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010631.1|UniProtKB=W5MXA8 W5MXA8 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010252.1|UniProtKB=W5MVZ9 W5MVZ9 PTHR10373:SF33 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;regulation of metabolic process#GO:0019222;Wnt signaling pathway#GO:0016055;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Angiogenesis#P00005>TCF#P00242;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143 LEPOC|Ensembl=ENSLOCG00000008183.1|UniProtKB=W5MNI6 W5MNI6 PTHR10194:SF3 RAS GTPASE-ACTIVATING PROTEINS RASGAP-ACTIVATING-LIKE PROTEIN 1 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 LEPOC|Ensembl=ENSLOCG00000012293.1|UniProtKB=W5N3C2 W5N3C2 PTHR24416:SF343 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of lipid biosynthetic process#GO:0046890;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of lipid metabolic process#GO:0019216;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 LEPOC|Ensembl=ENSLOCG00000000990.1|UniProtKB=W5LYA8 W5LYA8 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006929.1|UniProtKB=W5MJ29 W5MJ29 PTHR11909:SF99 CASEIN KINASE-RELATED INACTIVE SERINE_THREONINE-PROTEIN KINASE VRK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004759.1|UniProtKB=W5MBF0 W5MBF0 PTHR45964:SF7 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 2 LEPOC|Ensembl=ENSLOCG00000005298.1|UniProtKB=W5MDC6 W5MDC6 PTHR24049:SF19 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 2 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;establishment or maintenance of bipolar cell polarity#GO:0061245 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011654.1|UniProtKB=W5N111 W5N111 PTHR23122:SF33 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 3 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014134.1|UniProtKB=W5N9V1 W5N9V1 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000907.1|UniProtKB=W5LY03 W5LY03 PTHR23115:SF271 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008759.1|UniProtKB=W5MQK2 W5MQK2 PTHR42883:SF2 GLUCOSE-1-PHOSPHATE THYMIDYLTRANSFERASE THYMIDYLYLTRANSFERASE nucleotidyltransferase#PC00174 O-antigen biosynthesis#P02757>dTDP-glucose pyrophosphorylase#P03046 LEPOC|Ensembl=ENSLOCG00000000753.1|UniProtKB=W5LXI2 W5LXI2 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000018103.1|UniProtKB=W5NNJ5 W5NNJ5 PTHR24230:SF84 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011579.1|UniProtKB=W5N0R5 W5N0R5 DLK1 PTHR24044:SF507 NOTCH LIGAND FAMILY MEMBER NOTCH HOMOLOG 2 N-TERMINAL-LIKE PROTEIN B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008753.1|UniProtKB=W5MQK1 W5MQK1 PTHR11596:SF90 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006971.1|UniProtKB=W5MJ74 W5MJ74 PTHR12167:SF4 C-TYPE NATRIURETIC PEPTIDE NATRIURETIC PEPTIDE C-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000004255.1|UniProtKB=W5M9N3 W5M9N3 PTHR24251:SF50 OVOCHYMASE-RELATED ATTRACTIN-LIKE 1A serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014129.1|UniProtKB=W5N9U5 W5N9U5 PTHR35076:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000004546.1|UniProtKB=W5MAP7 W5MAP7 PTHR15591:SF14 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018325.1|UniProtKB=W5NP67 W5NP67 PTHR48051:SF55 FAMILY NOT NAMED MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001816.1|UniProtKB=W5M155 W5M155 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018164.1|UniProtKB=W5NNQ6 W5NNQ6 PTHR10489:SF730 CELL ADHESION MOLECULE CHEMOKINE XC RECEPTOR 1 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000007785.1|UniProtKB=W5MM55 W5MM55 PTHR14049:SF15 LEPRECAN 1 PROCOLLAGEN-PROLINE 3-DIOXYGENASE 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000016477.1|UniProtKB=W5NI95 W5NI95 PTHR15572:SF2 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN-LIKE positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000003284.1|UniProtKB=W5M694 W5M694 PTHR48015:SF14 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE TAO3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000052.1|UniProtKB=W5LVA5 W5LVA5 PTHR24241:SF20 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V2 RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;response to organic substance#GO:0010033;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002777.1|UniProtKB=W5M4L5 W5M4L5 PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015348.1|UniProtKB=W5NE27 W5NE27 PTHR14064:SF3 CHONDROMODULIN-RELATED TENOMODULIN regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;negative regulation of angiogenesis#GO:0016525;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;negative regulation of cellular process#GO:0048523 LEPOC|Ensembl=ENSLOCG00000003858.1|UniProtKB=W5M898 W5M898 PTHR14390:SF2 G PATCH DOMAIN CONTAINING PROTEIN 3 G PATCH DOMAIN-CONTAINING PROTEIN 3 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000009152.1|UniProtKB=W5MS00 W5MS00 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] cation binding#GO:0043169;antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;response to reactive oxygen species#GO:0000302;cellular response to stress#GO:0033554;metabolic process#GO:0008152 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004664.1|UniProtKB=W5MB29 W5MB29 PTHR11785:SF517 AMINO ACID TRANSPORTER SI:DKEYP-120H9.1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;basic amino acid transmembrane transporter activity#GO:0015174;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;regulation of nitrogen compound metabolic process#GO:0051171;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organic acid transmembrane transport#GO:1903825;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016798.1|UniProtKB=W5NJF4 W5NJF4 PTHR10426:SF130 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000002019.1|UniProtKB=W5M1T3 W5M1T3 PTHR11848:SF29 TGF-BETA FAMILY INHIBIN BETA B CHAIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700 LEPOC|Ensembl=ENSLOCG00000016440.1|UniProtKB=W5NI46 W5NI46 PTHR10578:SF107 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 1 oxidoreductase#PC00176 ATP synthesis#P02721>FMN FeS#P02792 LEPOC|Ensembl=ENSLOCG00000015474.1|UniProtKB=W5NEI7 W5NEI7 RELN PTHR11841:SF1 REELIN REELIN extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000011686.1|UniProtKB=W5N165 W5N165 PTHR11590:SF42 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE COAGULATION FACTOR XIII A CHAIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of body fluid levels#GO:0050878;cellular metabolic process#GO:0044237;wound healing#GO:0042060;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein activation cascade#GO:0072376;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 transferase#PC00220;metabolite interconversion enzyme#PC00262 Blood coagulation#P00011>FXIII#P00453;Blood coagulation#P00011>FXIIIa#P00419 LEPOC|Ensembl=ENSLOCG00000017806.1|UniProtKB=W5NMQ1 W5NMQ1 PTHR12974:SF34 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5C adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000018155.1|UniProtKB=W5NNP7 W5NNP7 PTHR11309:SF86 FRIZZLED FRIZZLED-10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000014947.1|UniProtKB=W5NCP9 W5NCP9 PTHR45930:SF1 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A2 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of Wnt signaling pathway#GO:0030177;nervous system development#GO:0007399;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;central nervous system development#GO:0007417;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009957.1|UniProtKB=W5MUW6 W5MUW6 PTHR47266:SF33 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015004.1|UniProtKB=W5NCW5 W5NCW5 PTHR10555:SF129 SORTING NEXIN SORTING NEXIN-1 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009477.1|UniProtKB=W5MT58 W5MT58 PTHR18945:SF883 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A-LIKE ISOFORM X1 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009437.1|UniProtKB=W5MT08 W5MT08 PTHR11955:SF69 FATTY ACID BINDING PROTEIN GASTROTROPIN fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001369.1|UniProtKB=W5LZL4 W5LZL4 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000016673.1|UniProtKB=W5NIZ1 W5NIZ1 PTHR12181:SF10 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;lipid catabolic process#GO:0016042;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;response to insulin#GO:0032868;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;positive regulation of biosynthetic process#GO:0009891;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;glycerolipid biosynthetic process#GO:0045017;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;fatty acid catabolic process#GO:0009062;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000007017.1|UniProtKB=W5MJD6 W5MJD6 RPS15A PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A 40S RIBOSOMAL PROTEIN S15A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001311.1|UniProtKB=W5LZD8 W5LZD8 PTHR11292:SF7 T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN-RELATED cell surface#GO:0009986;cellular anatomical entity#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004363.1|UniProtKB=W5MA06 W5MA06 PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007555.1|UniProtKB=W5MLD5 W5MLD5 PTHR23220:SF9 INTEGRIN ALPHA INTEGRIN ALPHA-6 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;response to stimulus#GO:0050896;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000016085.1|UniProtKB=W5NGR0 W5NGR0 PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000003844.1|UniProtKB=W5M880 W5M880 PTHR13958:SF3 CENTROSOME-ASSOCIATED PROTEIN 350 CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000007223.1|UniProtKB=W5MK30 W5MK30 PTHR14098:SF3 SH2 DOMAIN CONTAINING PROTEIN B-CELL LINKER PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 B cell activation#P00010>BLNK#P00394 LEPOC|Ensembl=ENSLOCG00000017271.1|UniProtKB=W5NL54 W5NL54 SLC35D3 PTHR11132:SF515 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER D3 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010600.1|UniProtKB=W5MX73 W5MX73 PTHR24028:SF9 CADHERIN-87A PROTOCADHERIN-18 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000002794.1|UniProtKB=W5M4H7 W5M4H7 PTHR10204:SF34 NAD P H OXIDOREDUCTASE-RELATED NAD(P)H DEHYDROGENASE [QUINONE] 1 ISOFORM 1 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010174.1|UniProtKB=W5MVP6 W5MVP6 SYT16 PTHR46129:SF4 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-16 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017807.1|UniProtKB=W5NMQ2 W5NMQ2 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004504.1|UniProtKB=W5MAH5 W5MAH5 PTHR24085:SF1 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#P06713;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06893;CCKR signaling map#P06959>NR4A1#G07289;CCKR signaling map#P06959>NR4A1#G06995;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06679 LEPOC|Ensembl=ENSLOCG00000003988.1|UniProtKB=W5M8Q4 W5M8Q4 PTHR17601:SF1 RAFTLIN-RELATED RAFTLIN-2 LEPOC|Ensembl=ENSLOCG00000018194.1|UniProtKB=W5NNT6 W5NNT6 PTHR28649:SF5 PROTEIN REPRIMO-RELATED REPRIMO, TP53-DEPENDENT G2 ARREST MEDIATOR HOMOLOG 3 LEPOC|Ensembl=ENSLOCG00000002892.1|UniProtKB=W5M4U0 W5M4U0 PTHR24061:SF504 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR ISOFORM X2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004521.1|UniProtKB=W5MAJ7 W5MAJ7 PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014560.1|UniProtKB=W5NBB5 W5NBB5 PTHR11851:SF116 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;protein processing involved in protein targeting to mitochondrion#GO:0006627;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein maturation#GO:0051604;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007626.1|UniProtKB=W5MLJ8 W5MLJ8 PTHR22996:SF2 MAHOGUNIN E3 UBIQUITIN-PROTEIN LIGASE MGRN1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;endosome to lysosome transport#GO:0008333;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of cAMP-mediated signaling#GO:0043949;post-translational protein modification#GO:0043687;regulation of intracellular signal transduction#GO:1902531;lysosomal transport#GO:0007041;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;protein ubiquitination#GO:0016567;negative regulation of response to stimulus#GO:0048585;protein modification by small protein conjugation or removal#GO:0070647;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of response to stimulus#GO:0048583;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014547.1|UniProtKB=W5NB94 W5NB94 PTHR47981:SF13 RAB FAMILY RAS-RELATED PROTEIN RAB-7A lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017409.1|UniProtKB=W5NLK5 W5NLK5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012729.1|UniProtKB=W5N4V5 W5N4V5 INF2 PTHR46345:SF5 INVERTED FORMIN-2 INVERTED FORMIN-2 LEPOC|Ensembl=ENSLOCG00000009286.1|UniProtKB=W5MSH8 W5MSH8 PTHR47633:SF3 IMMUNOGLOBULIN STRIATED MUSCLE PREFERENTIALLY EXPRESSED PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 LEPOC|Ensembl=ENSLOCG00000013750.1|UniProtKB=W5N8J7 W5N8J7 PTHR10656:SF48 CELL FATE DETERMINING PROTEIN MAB21-RELATED TRANSMEMBRANE PROTEIN 102 transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000012466.1|UniProtKB=W5N400 W5N400 PTHR23255:SF50 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000007813.1|UniProtKB=W5MM86 W5MM86 PTHR10658:SF27 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN BETA ISOFORM cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007165.1|UniProtKB=W5MK01 W5MK01 PTHR42861:SF18 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 2 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890 inorganic ion homeostasis#GO:0098771;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;regulation of muscle contraction#GO:0006937;calcium-mediated signaling#GO:0019722;macroautophagy#GO:0016236;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of system process#GO:0044057;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of heart contraction#GO:0008016;calcium ion transmembrane transport#GO:0070588;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;autophagy#GO:0006914 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015697.1|UniProtKB=W5NFB2 W5NFB2 PTHR16095:SF9 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER PROLINE AND SERINE-RICH PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000008429.1|UniProtKB=W5MPD7 W5MPD7 PTHR19424:SF0 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR BINDING PROTEIN 1 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008469.1|UniProtKB=W5MPK0 W5MPK0 PTHR31997:SF0 AGAP003710-PA PRIMARY CILIUM ASSEMBLY PROTEIN FAM149B1 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 LEPOC|Ensembl=ENSLOCG00000005586.1|UniProtKB=W5MED8 W5MED8 PTHR11920:SF506 GUANYLYL CYCLASE GUANYLATE CYCLASE adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000017447.1|UniProtKB=W5NLP3 W5NLP3 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003809.1|UniProtKB=W5M858 W5M858 PTHR15012:SF33 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011460.1|UniProtKB=W5N0D1 W5N0D1 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;snRNA binding#GO:0017069;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;translational elongation#GO:0006414 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytosol#GO:0005829;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000016663.1|UniProtKB=W5NIX5 W5NIX5 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014218.1|UniProtKB=W5NA53 W5NA53 PTHR22804:SF42 AGGRECAN/VERSICAN PROTEOGLYCAN AGGRECAN CORE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000011153.1|UniProtKB=W5MZ95 W5MZ95 PTHR21228:SF9 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA processing#GO:0000963;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012298.1|UniProtKB=W5N3C5 W5N3C5 PTHR13563:SF13 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG A RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000015557.1|UniProtKB=W5NEU0 W5NEU0 PTHR12316:SF26 NINJURIN-RELATED NINJURIN-2 cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003491.1|UniProtKB=W5M6Y6 W5M6Y6 PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1L cellular anatomical entity#GO:0110165;membrane#GO:0016020;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000017384.1|UniProtKB=W5NLI0 W5NLI0 PTHR45773:SF6 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 3 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of synapse assembly#GO:0051965;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008211.1|UniProtKB=W5MNL8 W5MNL8 PTHR43884:SF1 ACYL-COA DEHYDROGENASE SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016700.1|UniProtKB=W5NJ27 W5NJ27 PTHR12197:SF193 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD N-LYSINE METHYLTRANSFERASE SMYD2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000016821.1|UniProtKB=W5NJI5 W5NJI5 PTHR14463:SF5 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 2 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016391.1|UniProtKB=W5NHY2 W5NHY2 PTHR45712:SF14 AGAP008170-PA DECORIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000017972.1|UniProtKB=W5NN64 W5NN64 PTHR11711:SF427 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012517.1|UniProtKB=W5N456 W5N456 PTHR23196:SF1 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007376.1|UniProtKB=W5MKR8 W5MKR8 PTHR45627:SF9 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 7 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Opioid proopiomelanocortin pathway#P05917>AC#P06011;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;GABA-B receptor II signaling#P05731>AC#P05760;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;Enkephalin release#P05913>AC#P05978;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;Opioid proenkephalin pathway#P05915>AC#P05993;Opioid prodynorphin pathway#P05916>AC#P06001;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439 LEPOC|Ensembl=ENSLOCG00000016385.1|UniProtKB=W5NHY0 W5NHY0 PTHR13146:SF0 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 35 MEMBER F6 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003335.1|UniProtKB=W5M6D3 W5M6D3 PTHR12015:SF155 SMALL INDUCIBLE CYTOKINE A CHEMOKINE (C-C MOTIF) LIGAND 44 cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002983.1|UniProtKB=W5M559 W5M559 PTHR42886:SF83 RE40534P-RELATED PROTEIN ABHD8 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;lipid homeostasis#GO:0055088;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013006.1|UniProtKB=W5N5W1 W5N5W1 PTHR11655:SF16 60S/50S RIBOSOMAL PROTEIN L6/L9 60S RIBOSOMAL PROTEIN L9 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001349.1|UniProtKB=W5LZI4 W5LZI4 KCNQ4 PTHR47735:SF7 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004729.1|UniProtKB=W5MBB3 W5MBB3 PTHR12317:SF14 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000002034.1|UniProtKB=W5M1U8 W5M1U8 PTHR16002:SF5 TRANSMEMBRANE PROTEIN 248-LIKE TRANSMEMBRANE PROTEIN 248 LEPOC|Ensembl=ENSLOCG00000014344.1|UniProtKB=W5NAK2 W5NAK2 PTHR46512:SF10 PEPTIDYLPROLYL ISOMERASE FK506-BINDING PROTEIN-LIKE chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017431.1|UniProtKB=W5NLM7 W5NLM7 PTHR12002:SF89 CLAUDIN CLAUDIN-4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000009510.1|UniProtKB=W5MTB6 W5MTB6 PTHR24353:SF155 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011024.1|UniProtKB=W5MYR9 W5MYR9 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012303.1|UniProtKB=W5N3D6 W5N3D6 SRCIN1 PTHR22741:SF5 P140CAP/SNIP-RELATED SRC KINASE SIGNALING INHIBITOR 1 regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of synapse structure or activity#GO:0050803;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of postsynapse organization#GO:0099175;regulation of neuron projection development#GO:0010975 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;asymmetric synapse#GO:0032279;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;postsynapse#GO:0098794;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000004140.1|UniProtKB=W5M9A5 W5M9A5 PTHR12447:SF4 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008700.1|UniProtKB=W5MQC7 W5MQC7 PTHR31626:SF2 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171B LEPOC|Ensembl=ENSLOCG00000010842.1|UniProtKB=W5MY45 W5MY45 PTHR45736:SF6 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 2 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002612.1|UniProtKB=W5M3W1 W5M3W1 PTHR19818:SF84 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN GLIS2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015885.1|UniProtKB=W5NG05 W5NG05 PTHR24390:SF70 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009757.1|UniProtKB=W5MU66 W5MU66 DLEC1 PTHR46348:SF1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015159.1|UniProtKB=W5NDF1 W5NDF1 PTHR24278:SF31 COAGULATION FACTOR COAGULATION FACTOR IX extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 Blood coagulation#P00011>FXIa#P00434;Blood coagulation#P00011>FIX#P00444;Blood coagulation#P00011>FIXa#P00422;Blood coagulation#P00011>FXI#P00460 LEPOC|Ensembl=ENSLOCG00000009334.1|UniProtKB=W5MSN2 W5MSN2 PTHR11960:SF29 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E FAMILY MEMBER 1C nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016265.1|UniProtKB=W5NHF6 W5NHF6 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011134.1|UniProtKB=W5MZ67 W5MZ67 PTHR21393:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN MS27 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014319.1|UniProtKB=W5NAH1 W5NAH1 PTHR12352:SF13 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 1 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;extracellular matrix binding#GO:0050840;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604;extracellular region#GO:0005576;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000012142.1|UniProtKB=W5N2S7 W5N2S7 PTHR24340:SF31 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014911.1|UniProtKB=W5NCK4 W5NCK4 PTHR12474:SF1 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN 3 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of metabolic process#GO:0009893;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;positive regulation of macroautophagy#GO:0016239;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003302.1|UniProtKB=W5M6A3 W5M6A3 PTHR42698:SF1 GTPASE ERA GTPASE ERA, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;rRNA binding#GO:0019843 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;non-membrane-bounded organelle assembly#GO:0140694;ribosomal small subunit biogenesis#GO:0042274 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007192.1|UniProtKB=W5MJZ5 W5MJZ5 PTHR11232:SF76 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014254.1|UniProtKB=W5NA89 W5NA89 PTHR15036:SF17 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010320.1|UniProtKB=W5MWB2 W5MWB2 PTHR11905:SF14 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 22 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000999.1|UniProtKB=W5LYB5 W5LYB5 PTHR47229:SF1 TRANSMEMBRANE PROTEIN 141 TRANSMEMBRANE PROTEIN 141 LEPOC|Ensembl=ENSLOCG00000007248.1|UniProtKB=W5MK61 W5MK61 PTHR15431:SF19 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20-RELATED organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000016015.1|UniProtKB=W5NGG7 W5NGG7 PTHR45942:SF1 PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1 PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B, ALPHA phosphatase binding#GO:0019902;phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;protein binding#GO:0005515;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;calcineurin-mediated signaling#GO:0097720;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 Wnt signaling pathway#P00057>Calcineurin#P01446 LEPOC|Ensembl=ENSLOCG00000004907.1|UniProtKB=W5MBZ8 W5MBZ8 PTHR12544:SF33 GLUTAMINASE GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 dicarboxylic acid metabolic process#GO:0043648;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015482.1|UniProtKB=W5NEJ7 W5NEJ7 PTHR45624:SF23 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN ISOFORM X1 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic cation transport#GO:0015695;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 envelope#GO:0031975;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006286.1|UniProtKB=W5MGT5 W5MGT5 PTHR15744:SF1 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008909.1|UniProtKB=W5MR45 W5MR45 TSHR PTHR24372:SF0 GLYCOPROTEIN HORMONE RECEPTOR THYROTROPIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004795.1|UniProtKB=W5MBJ7 W5MBJ7 PTHR11346:SF80 GALECTIN GALECTIN-9C carbohydrate derivative binding#GO:0097367;carbohydrate binding#GO:0030246;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of cellular metabolic process#GO:0031325;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of biosynthetic process#GO:0009891;negative regulation of multicellular organismal process#GO:0051241;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;regulation of cytokine production#GO:0001817;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;regulation of T cell proliferation#GO:0042129;positive regulation of cellular process#GO:0048522;negative regulation of cell adhesion#GO:0007162;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of leukocyte activation#GO:0002694;regulation of cellular biosynthetic process#GO:0031326;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000015488.1|UniProtKB=W5NEK7 W5NEK7 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 ATPase complex#GO:1904949;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013581.1|UniProtKB=W5N7Z0 W5N7Z0 PTHR23349:SF41 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012856.1|UniProtKB=W5N5C3 W5N5C3 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;outer dynein arm#GO:0036157;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000001743.1|UniProtKB=W5M0Z8 W5M0Z8 PTHR24020:SF18 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000009118.1|UniProtKB=W5MRW4 W5MRW4 PTHR12750:SF10 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008496.1|UniProtKB=W5MPN1 W5MPN1 PTHR33538:SF1 PROTEIN GAMETE EXPRESSED 1 PROTEIN BRAMBLEBERRY LEPOC|Ensembl=ENSLOCG00000003036.1|UniProtKB=W5M5C7 W5M5C7 PTGS1 PTHR11903:SF6 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 1 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 LEPOC|Ensembl=ENSLOCG00000016840.1|UniProtKB=W5NJK4 W5NJK4 PTHR11346:SF22 GALECTIN GALECTIN-8 carbohydrate binding#GO:0030246;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002611.1|UniProtKB=W5M3X2 W5M3X2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009528.1|UniProtKB=W5MTE3 W5MTE3 PTHR22633:SF1 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2 signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;intracellular signal transduction#GO:0035556;plasma membrane bounded cell projection morphogenesis#GO:0120039;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015682.1|UniProtKB=W5NF98 W5NF98 PTHR18939:SF4 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007663.1|UniProtKB=W5MLP2 W5MLP2 PTHR46257:SF1 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>SHP2#P00647;Angiogenesis#P00005>SHP2#P00181;Interferon-gamma signaling pathway#P00035>PTP#P00960 LEPOC|Ensembl=ENSLOCG00000016007.1|UniProtKB=W5NGG2 W5NGG2 PTHR12680:SF2 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF2 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011582.1|UniProtKB=W5N0R9 W5N0R9 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 cellular localization#GO:0051641;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;transport#GO:0006810;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;localization#GO:0051179;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of hydrolase activity#GO:0051336;intracellular transport#GO:0046907;nuclear transport#GO:0051169 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003563.1|UniProtKB=W5M759 W5M759 PTHR24363:SF0 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE KINASE LIKE DOMAIN CONTAINING 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005752.1|UniProtKB=W5MF05 W5MF05 PTHR24377:SF964 IP01015P-RELATED ZINC FINGER PROTEIN 408 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001037.1|UniProtKB=W5LYF2 W5LYF2 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002466.1|UniProtKB=W5M3G6 W5M3G6 PPP2R3B PTHR14095:SF1 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT BETA phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000401.1|UniProtKB=W5LWD1 W5LWD1 PTHR23050:SF536 CALCIUM BINDING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 LEPOC|Ensembl=ENSLOCG00000013045.1|UniProtKB=W5N618 W5N618 PTHR24412:SF135 KELCH PROTEIN KELCH-LIKE PROTEIN 5 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001475.1|UniProtKB=W5LZY8 W5LZY8 PTHR10878:SF22 SEGMENT POLARITY PROTEIN DISHEVELLED DIXIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012391.1|UniProtKB=W5N3P9 W5N3P9 PTHR10334:SF461 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001188.1|UniProtKB=W5LYZ1 W5LYZ1 PTHR11216:SF63 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012799.1|UniProtKB=W5N539 W5N539 PTHR24243:SF207 G-PROTEIN COUPLED RECEPTOR PYROKININ-1 RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008342.1|UniProtKB=W5MP26 W5MP26 PTHR45849:SF1 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000000650.1|UniProtKB=W5LX62 W5LX62 PTHR23043:SF24 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014447.1|UniProtKB=W5NAX3 W5NAX3 SEC61A1 PTHR10906:SF19 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1 signal sequence binding#GO:0005048;transmembrane transporter activity#GO:0022857;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein transmembrane transporter activity#GO:0008320;protein-containing complex binding#GO:0044877;transporter activity#GO:0005215 cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;post-translational protein targeting to membrane, translocation#GO:0031204;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012072.1|UniProtKB=W5N2J1 W5N2J1 FCHSD1 PTHR15735:SF4 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 1 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;trans-synaptic signaling#GO:0099537;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of protein polymerization#GO:0032271;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;neuromuscular junction#GO:0031594 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003811.1|UniProtKB=W5M855 W5M855 PTHR10796:SF36 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;system process#GO:0003008;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002613.1|UniProtKB=W5M3W7 W5M3W7 PTHR22738:SF3 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 6 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004239.1|UniProtKB=W5M9K9 W5M9K9 PTHR45829:SF2 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 36 nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial genome maintenance#GO:0000002;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;nucleobase-containing compound transport#GO:0015931;mitochondrion organization#GO:0007005;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015291.1|UniProtKB=W5NDV3 W5NDV3 PTHR45716:SF4 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000006403.1|UniProtKB=W5MH77 W5MH77 ACTR5 PTHR11937:SF16 ACTIN ACTIN-RELATED PROTEIN 5 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016492.1|UniProtKB=W5NIB2 W5NIB2 PTHR31634:SF2 BLOC-1-RELATED COMPLEX SUBUNIT 5 BLOC-1-RELATED COMPLEX SUBUNIT 5 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;microtubule-based movement#GO:0007018;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;transport along microtubule#GO:0010970;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;lysosome localization#GO:0032418;microtubule-based transport#GO:0099111;regulation of transport#GO:0051049;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;positive regulation of biological process#GO:0048518;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;lysosome#GO:0005764;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;cell junction#GO:0030054;membrane#GO:0016020;lytic vacuole#GO:0000323;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000000741.1|UniProtKB=W5LXG5 W5LXG5 PTHR10462:SF49 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014802.1|UniProtKB=W5NC66 W5NC66 LONRF3 PTHR23327:SF41 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005159.1|UniProtKB=W5MCV2 W5MCV2 PTHR15710:SF21 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF126 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002001.1|UniProtKB=W5M1U2 W5M1U2 PTHR18966:SF171 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 4 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;sodium channel activity#GO:0005272;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA4#P01001;Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796 LEPOC|Ensembl=ENSLOCG00000017562.1|UniProtKB=W5NM08 W5NM08 PTHR11214:SF87 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 8 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000011850.1|UniProtKB=W5N1Q7 W5N1Q7 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001642.1|UniProtKB=W5M0I3 W5M0I3 PTHR12644:SF1 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Huntington disease#P00029>Arp2/3 complex#P00811 LEPOC|Ensembl=ENSLOCG00000006307.1|UniProtKB=W5MGW1 W5MGW1 PTHR13388:SF23 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C LEPOC|Ensembl=ENSLOCG00000018139.1|UniProtKB=W5NNN1 W5NNN1 PTHR12002:SF35 CLAUDIN CLAUDIN-5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000012381.1|UniProtKB=W5N3N4 W5N3N4 PTHR10868:SF1 SIGMA 1-TYPE OPIOID RECEPTOR-RELATED SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008920.1|UniProtKB=W5MR68 W5MR68 PTHR11566:SF23 DYNAMIN DYNAMIN-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;receptor internalization#GO:0031623;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of organelle localization#GO:0051656;vesicle-mediated transport in synapse#GO:0099003 supramolecular complex#GO:0099080;synapse#GO:0045202;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005496.1|UniProtKB=W5ME23 W5ME23 PTHR45973:SF36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTRIOLIN phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000005242.1|UniProtKB=W5MD56 W5MD56 PTHR14002:SF21 ENDOGLIN/TGF-BETA RECEPTOR TYPE III SI:CH211-103F14.3-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010171.1|UniProtKB=W5MVN9 W5MVN9 TRABD2B PTHR31120:SF8 METALLOPROTEASE TIKI METALLOPROTEASE TIKI2 metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014351.1|UniProtKB=W5NAL1 W5NAL1 DMWD PTHR14107:SF15 WD REPEAT PROTEIN DYSTROPHIA MYOTONICA WD REPEAT-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007881.1|UniProtKB=W5MMG0 W5MMG0 LRRC70 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011593.1|UniProtKB=W5N0T7 W5N0T7 WDR25 PTHR44566:SF1 TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN WD REPEAT-CONTAINING PROTEIN 25 LEPOC|Ensembl=ENSLOCG00000001462.1|UniProtKB=W5LZX8 W5LZX8 LDLRAD3 PTHR24270:SF24 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000008040.1|UniProtKB=W5MN04 W5MN04 PTHR24412:SF146 KELCH PROTEIN KELCH-LIKE PROTEIN 41 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008280.1|UniProtKB=W5MNU8 W5MNU8 PTHR14002:SF38 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012099.1|UniProtKB=W5N2N2 W5N2N2 PTHR47961:SF12 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED HELICASE POLQ-LIKE DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008347.1|UniProtKB=W5MP41 W5MP41 PTHR10037:SF278 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014556.1|UniProtKB=W5NBB1 W5NBB1 SHKBP1 PTHR15859:SF5 SETA BINDING PROTEIN 1 SH3KBP1-BINDING PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003314.1|UniProtKB=W5M6B5 W5M6B5 PTHR10026:SF64 CYCLIN CYCLIN-L1 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000003826.1|UniProtKB=W5M854 W5M854 RSRC1 PTHR31968:SF4 SERINE/ARGININE-RELATED PROTEIN 53 SERINE_ARGININE-RELATED PROTEIN 53 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011657.1|UniProtKB=W5N117 W5N117 PTHR10693:SF21 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001196.1|UniProtKB=W5LYY8 W5LYY8 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004026.1|UniProtKB=W5M8U9 W5M8U9 PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE SUBUNIT G 2, MITOCHONDRIAL-RELATED monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014874.1|UniProtKB=W5NCG0 W5NCG0 PTHR11486:SF71 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 17 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000016327.1|UniProtKB=W5NHP7 W5NHP7 PTHR12496:SF9 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000000693.1|UniProtKB=W5LXB6 W5LXB6 PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 LEPOC|Ensembl=ENSLOCG00000015997.1|UniProtKB=W5NGE4 W5NGE4 PTHR13630:SF1 GAMMA-SECRETASE-ACTIVATING PROTEIN GAMMA-SECRETASE-ACTIVATING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014047.1|UniProtKB=W5N9L0 W5N9L0 PTHR11461:SF49 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 1 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of gene expression#GO:0010629;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of wound healing#GO:0061041;regulation of vasculature development#GO:1901342;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;regulation of response to stress#GO:0080134;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to wounding#GO:1903034;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of angiogenesis#GO:0016525;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 CCKR signaling map#P06959>PAI1#G07281;Plasminogen activating cascade#P00050>PAI-1#P01245;Blood coagulation#P00011>PAI-1#P00411;CCKR signaling map#P06959>PAI1#G06987;p53 pathway#P00059>PAI#G04700 LEPOC|Ensembl=ENSLOCG00000009267.1|UniProtKB=W5MSE2 W5MSE2 PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1_MAPK8-ASSOCIATED MEMBRANE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002695.1|UniProtKB=W5M458 W5M458 PTHR46908:SF4 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN LEPOC|Ensembl=ENSLOCG00000002272.1|UniProtKB=W5M2P7 W5M2P7 PTHR46104:SF1 GENE 9195-RELATED-RELATED GENE 9195-RELATED LEPOC|Ensembl=ENSLOCG00000002095.1|UniProtKB=W5M223 W5M223 PTHR44436:SF1 F-BOX/WD REPEAT-CONTAINING PROTEIN 2 F-BOX_WD REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016687.1|UniProtKB=W5NJ07 W5NJ07 PTHR45827:SF2 SORTING NEXIN SORTING NEXIN-9 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cell division#GO:0051301;cellular localization#GO:0051641;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;cell cycle process#GO:0022402;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytokinesis#GO:0000910;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008850.1|UniProtKB=W5MQW8 W5MQW8 PTHR46526:SF1 CHORDIN CHORDIN protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regionalization#GO:0003002;developmental process#GO:0032502;dorsal/ventral pattern formation#GO:0009953;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 DPP-SCW signaling pathway#P06212>SOG#P06266;BMP/activin signaling pathway-drosophila#P06211>SOG#P06252;SCW signaling pathway#P06216>SOG#P06335;DPP signaling pathway#P06213>SOG#P06293 LEPOC|Ensembl=ENSLOCG00000003869.1|UniProtKB=W5M8A8 W5M8A8 EEF1AKMT3 PTHR14614:SF5 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN EEF1A LYSINE METHYLTRANSFERASE 3 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005827.1|UniProtKB=W5MF77 W5MF77 PTHR28676:SF1 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 1 protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;enzyme regulator activity#GO:0030234;signaling receptor binding#GO:0005102;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;protein binding#GO:0005515;protein kinase binding#GO:0019901 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000004758.1|UniProtKB=W5MBF1 W5MBF1 PTHR15622:SF12 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 1 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000009945.1|UniProtKB=W5MUU9 W5MUU9 PTHR10155:SF7 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 LEPOC|Ensembl=ENSLOCG00000014783.1|UniProtKB=W5NC43 W5NC43 PTHR14633:SF3 LITTLE ELONGATION COMPLEX SUBUNIT 2 LITTLE ELONGATION COMPLEX SUBUNIT 2 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;ncRNA transcription#GO:0098781;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000001077.1|UniProtKB=W5LYK7 W5LYK7 PTHR28584:SF1 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228B LEPOC|Ensembl=ENSLOCG00000003366.1|UniProtKB=W5M6I1 W5M6I1 PTHR15288:SF5 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2B regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009640.1|UniProtKB=W5MTS3 W5MTS3 PTHR31037:SF1 RELT-LIKE PROTEIN 1-RELATED RELT-LIKE PROTEIN 1 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015367.1|UniProtKB=W5NE53 W5NE53 PTHR46925:SF4 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-P RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;positive regulation of locomotion#GO:0040017;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;sperm flagellum#GO:0036126;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CCKR signaling map#P06959>TACR1#G06985;CCKR signaling map#P06959>TACR1#G07279 LEPOC|Ensembl=ENSLOCG00000012396.1|UniProtKB=W5N3Q6 W5N3Q6 PTHR35259:SF1 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 LEPOC|Ensembl=ENSLOCG00000001829.1|UniProtKB=W5M165 W5M165 PTHR10507:SF0 CDC45-RELATED PROTEIN CELL DIVISION CONTROL PROTEIN 45 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;protein-containing complex organization#GO:0043933;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000015539.1|UniProtKB=W5NES4 W5NES4 EML6 PTHR13720:SF52 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018263.1|UniProtKB=W5NP05 W5NP05 PTHR13538:SF4 N-ACETYLTRANSFERASE 6 N-ALPHA-ACETYLTRANSFERASE 80 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;N-acyltransferase activity#GO:0016410;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein acylation#GO:0043543;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014869.1|UniProtKB=W5NCF8 W5NCF8 PTHR21646:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 3 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005247.1|UniProtKB=W5MD61 W5MD61 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000003637.1|UniProtKB=W5M7F9 W5M7F9 PTHR35249:SF2 DYNEIN REGULATORY COMPLEX SUBUNIT 7 DYNEIN REGULATORY COMPLEX SUBUNIT 7 cell motility#GO:0048870;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004368.1|UniProtKB=W5MA13 W5MA13 PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015795.1|UniProtKB=W5NFN5 W5NFN5 PTHR14776:SF1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006202.1|UniProtKB=W5MGI3 W5MGI3 PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010948.1|UniProtKB=W5MYG5 W5MYG5 PTHR22811:SF3 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 11 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000013454.1|UniProtKB=W5N7J0 W5N7J0 PTHR22760:SF4 GLYCOSYLTRANSFERASE GPI MANNOSYLTRANSFERASE 3 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015996.1|UniProtKB=W5NGD8 W5NGD8 PTHR19143:SF189 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBROLEUKIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001691.1|UniProtKB=W5M0P1 W5M0P1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012106.1|UniProtKB=W5N2P7 W5N2P7 PTHR12515:SF8 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 LEPOC|Ensembl=ENSLOCG00000007270.1|UniProtKB=W5MK85 W5MK85 PTHR28525:SF1 REACTIVE OXYGEN SPECIES MODULATOR 1 REACTIVE OXYGEN SPECIES MODULATOR 1 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization within membrane#GO:0051668;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000001591.1|UniProtKB=W5M0C3 W5M0C3 GET1 PTHR42650:SF1 TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003570.1|UniProtKB=W5M776 W5M776 PTHR11785:SF515 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013103.1|UniProtKB=W5N681 W5N681 PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007428.1|UniProtKB=W5MKY4 W5MKY4 PTHR45703:SF12 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 11 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016799.1|UniProtKB=W5NJF5 W5NJF5 PTHR31535:SF3 FAMILY NOT NAMED REGULATORY PROTEIN ZESTE LEPOC|Ensembl=ENSLOCG00000018342.1|UniProtKB=W5NP84 W5NP84 PTHR46341:SF2 PROTEIN FAM84B-RELATED PROTEIN LRATD2 LEPOC|Ensembl=ENSLOCG00000012783.1|UniProtKB=W5N527 W5N527 PTHR23042:SF6 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000018221.1|UniProtKB=W5NNW3 W5NNW3 MYADM PTHR17068:SF3 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER LEPOC|Ensembl=ENSLOCG00000014380.1|UniProtKB=W5NAP5 W5NAP5 PTHR13119:SF23 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013661.1|UniProtKB=W5N883 W5N883 PTHR24203:SF45 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN 6 LEPOC|Ensembl=ENSLOCG00000003572.1|UniProtKB=W5M770 W5M770 PTHR14948:SF46 NG5 DISPANIN SUBFAMILY A MEMBER 2B-LIKE-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005953.1|UniProtKB=W5MFN0 W5MFN0 PTHR24412:SF23 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007160.1|UniProtKB=W5MJV7 W5MJV7 PTHR14898:SF6 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008450.1|UniProtKB=W5MPG9 W5MPG9 C8orf82 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 LEPOC|Ensembl=ENSLOCG00000010737.1|UniProtKB=W5MXQ3 W5MXQ3 RDX PTHR23281:SF14 MERLIN/MOESIN/EZRIN/RADIXIN RADIXIN cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 microvillus#GO:0005902;filopodium#GO:0030175;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;actin-based cell projection#GO:0098858;adherens junction#GO:0005912;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008690.1|UniProtKB=W5MQB2 W5MQB2 PTHR21540:SF3 RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2 E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008487.1|UniProtKB=W5MPL6 W5MPL6 C5orf63 PTHR33558:SF1 GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003388.1|UniProtKB=W5M6K0 W5M6K0 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003538.1|UniProtKB=W5M758 W5M758 TCF4 PTHR11793:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>TCF7L2#P07126 LEPOC|Ensembl=ENSLOCG00000002553.1|UniProtKB=W5M3Q4 W5M3Q4 PTHR20991:SF0 PARATHYROID HORMONE-RESPONSIVE B1 GENE PROTEIN PTHB1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;BBSome#GO:0034464;membrane#GO:0016020;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000018174.1|UniProtKB=W5NNR6 W5NNR6 PTHR24249:SF376 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016533.1|UniProtKB=W5NIG0 W5NIG0 PTHR23138:SF141 RAN BINDING PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP50 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008325.1|UniProtKB=W5MP10 W5MP10 PTHR18945:SF23 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009914.1|UniProtKB=W5MUR5 W5MUR5 PTHR10037:SF208 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 10 SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000012734.1|UniProtKB=W5N4Y2 W5N4Y2 DNAH17 PTHR45703:SF4 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 17 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016922.1|UniProtKB=W5NJW3 W5NJW3 PTHR21590:SF4 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549 LEPOC|Ensembl=ENSLOCG00000009750.1|UniProtKB=W5MU56 W5MU56 PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017422.1|UniProtKB=W5NLL8 W5NLL8 PTHR23226:SF419 ZINC FINGER AND SCAN DOMAIN-CONTAINING FI21258P1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002404.1|UniProtKB=W5M365 W5M365 PTHR10809:SF155 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;cell projection organization#GO:0030030;membrane organization#GO:0061024;developmental process#GO:0032502;multicellular organism development#GO:0007275;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002172.1|UniProtKB=W5M2C2 W5M2C2 PTHR11347:SF209 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;heterocycle catabolic process#GO:0046700;cyclic nucleotide metabolic process#GO:0009187;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;nucleotide catabolic process#GO:0009166;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;response to stimulus#GO:0050896;aromatic compound catabolic process#GO:0019439;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000009074.1|UniProtKB=W5MRP7 W5MRP7 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 regulation of microtubule-based process#GO:0032886;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000014581.1|UniProtKB=W5NBE5 W5NBE5 PTHR11219:SF7 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-1 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000018171.1|UniProtKB=W5NNR3 W5NNR3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004252.1|UniProtKB=W5M9M3 W5M9M3 PTHR13523:SF3 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;mitochondrion organization#GO:0007005;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003130.1|UniProtKB=W5M5N6 W5M5N6 PTHR10336:SF51 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000001227.1|UniProtKB=W5LZ33 W5LZ33 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009740.1|UniProtKB=W5MU40 W5MU40 PTHR11485:SF34 TRANSFERRIN SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein targeting#GO:0006605;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000006555.1|UniProtKB=W5MHR1 W5MHR1 PTHR45832:SF10 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000015662.1|UniProtKB=W5NF71 W5NF71 PTHR10553:SF2 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;small nuclear ribonucleoprotein complex#GO:0030532;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;U12-type spliceosomal complex#GO:0005689;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U4 snRNP#GO:0005687;intracellular anatomical structure#GO:0005622;U5 snRNP#GO:0005682;cytoplasmic ribonucleoprotein granule#GO:0036464;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;spliceosomal tri-snRNP complex#GO:0097526;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004344.1|UniProtKB=W5M9Y2 W5M9Y2 PTHR21354:SF0 ZINC FINGER PROTEIN 511 ZINC FINGER PROTEIN 511 LEPOC|Ensembl=ENSLOCG00000014374.1|UniProtKB=W5NAP3 W5NAP3 PTHR11388:SF86 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005449.1|UniProtKB=W5MDW1 W5MDW1 PTHR11592:SF81 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006062.1|UniProtKB=W5MG18 W5MG18 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000018043.1|UniProtKB=W5NND5 W5NND5 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009818.1|UniProtKB=W5MUD4 W5MUD4 CD38 PTHR10912:SF9 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;positive regulation of immune system process#GO:0002684;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of immune system process#GO:0002682;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell activation#GO:0050867;regulation of lymphocyte activation#GO:0051249;positive regulation of biological process#GO:0048518;regulation of B cell proliferation#GO:0030888;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000011126.1|UniProtKB=W5MZ64 W5MZ64 PTHR12296:SF17 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4C regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013609.1|UniProtKB=W5N829 W5N829 PTHR45702:SF4 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 10 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 synapse#GO:0045202;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 LEPOC|Ensembl=ENSLOCG00000008723.1|UniProtKB=W5MQG4 W5MQG4 PTHR12450:SF11 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 EXTRACELLULAR SERINE_THREONINE PROTEIN KINASE FAM20C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 odontogenesis of dentin-containing tooth#GO:0042475;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;odontogenesis#GO:0042476;anatomical structure morphogenesis#GO:0009653;amelogenesis#GO:0097186;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;biomineral tissue development#GO:0031214;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012855.1|UniProtKB=W5N5B4 W5N5B4 ZBTB5 PTHR24394:SF17 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 5 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000099.1|UniProtKB=W5LVF3 W5LVF3 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008074.1|UniProtKB=W5MN48 W5MN48 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014300.1|UniProtKB=W5NAE6 W5NAE6 PTHR23101:SF72 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010008.1|UniProtKB=W5MV26 W5MV26 MSX1 PTHR24338:SF8 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012691.1|UniProtKB=W5N4Q9 W5N4Q9 PTHR17613:SF9 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 2 organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000013140.1|UniProtKB=W5N6C2 W5N6C2 PTHR10671:SF7 EPITHELIAL MEMBRANE PROTEIN-RELATED PERIPHERAL MYELIN PROTEIN 22 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004541.1|UniProtKB=W5MAM1 W5MAM1 BRD3 PTHR22880:SF246 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014420.1|UniProtKB=W5NAU2 W5NAU2 PTHR46223:SF4 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;histone methyltransferase activity#GO:0042054;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000005854.1|UniProtKB=W5MFA6 W5MFA6 PTHR15009:SF4 MUELLERIAN-INHIBITING FACTOR MUELLERIAN-INHIBITING FACTOR Gonadotropin-releasing hormone receptor pathway#P06664>MIS#P06750 LEPOC|Ensembl=ENSLOCG00000003499.1|UniProtKB=W5M6Y2 W5M6Y2 PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 deacetylase#PC00087;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017011.1|UniProtKB=W5NK66 W5NK66 AKR1D1 PTHR43827:SF14 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013429.1|UniProtKB=W5N7G0 W5N7G0 PTHR32059:SF0 RAB11-BINDING PROTEIN RELCH RAB11-BINDING PROTEIN RELCH trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000010803.1|UniProtKB=W5MXY3 W5MXY3 PTHR11842:SF11 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nucleoplasm#GO:0005654;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000016744.1|UniProtKB=W5NJ92 W5NJ92 PTHR22589:SF69 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, MUSCLE ISOFORM palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;organonitrogen compound metabolic process#GO:1901564;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010532.1|UniProtKB=W5MWZ6 W5MWZ6 PTHR14208:SF0 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000009281.1|UniProtKB=W5MSG3 W5MSG3 PTHR46402:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 5 HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000003723.1|UniProtKB=W5M7R6 W5M7R6 SS18L1 PTHR23107:SF21 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN CALCIUM-RESPONSIVE TRANSACTIVATOR transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of dendrite development#GO:0050773;positive regulation of RNA biosynthetic process#GO:1902680;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of DNA-templated transcription#GO:0006355;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010675.1|UniProtKB=W5MXH0 W5MXH0 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015245.1|UniProtKB=W5NDQ3 W5NDQ3 CNNM3 PTHR12064:SF27 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008832.1|UniProtKB=W5MQT9 W5MQT9 PTHR18640:SF5 SOLUTE CARRIER FAMILY 10 MEMBER 7 SODIUM_BILE ACID COTRANSPORTER 7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011298.1|UniProtKB=W5MZS5 W5MZS5 PTHR46759:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEPOC|Ensembl=ENSLOCG00000006150.1|UniProtKB=W5MGB8 W5MGB8 PTHR24347:SF373 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 2, SKELETAL_CARDIAC MUSCLE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 LEPOC|Ensembl=ENSLOCG00000004369.1|UniProtKB=W5MA23 W5MA23 PTHR24198:SF175 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004712.1|UniProtKB=W5MB98 W5MB98 PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002474.1|UniProtKB=W5M3F1 W5M3F1 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000676.1|UniProtKB=W5LX89 W5LX89 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014946.1|UniProtKB=W5NCP2 W5NCP2 PTHR24214:SF1 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008925.1|UniProtKB=W5MR65 W5MR65 PTHR13466:SF4 TEX2 PROTEIN-RELATED SMP-LTD DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;binding#GO:0005488 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004685.1|UniProtKB=W5MB55 W5MB55 PTHR46016:SF3 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF114 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000010986.1|UniProtKB=W5MYL7 W5MYL7 PTHR24366:SF64 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000011962.1|UniProtKB=W5N272 W5N272 PTHR13817:SF81 TITIN CONTACTIN 2 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010649.1|UniProtKB=W5MXD8 W5MXD8 PTHR12121:SF28 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL HOMOLOG 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000000773.1|UniProtKB=W5LXK1 W5LXK1 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011382.1|UniProtKB=W5N052 W5N052 PTHR21444:SF17 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 STIMULATED BY RETINOIC ACID GENE 6 PROTEIN-LIKE localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;transmembrane transport#GO:0055085;transport#GO:0006810;vitamin transport#GO:0051180;lipid localization#GO:0010876;cellular process#GO:0009987;import into cell#GO:0098657;lipid transport#GO:0006869 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004918.1|UniProtKB=W5MC05 W5MC05 PTHR45709:SF2 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016590.1|UniProtKB=W5NIN1 W5NIN1 PTHR35447:SF1 BH3-INTERACTING DOMAIN DEATH AGONIST BH3-INTERACTING DOMAIN DEATH AGONIST positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of mitochondrion organization#GO:0010821;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;regulation of organelle organization#GO:0033043;regulation of extrinsic apoptotic signaling pathway#GO:2001236;programmed cell death#GO:0012501;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of organelle organization#GO:0010638;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;mitochondrion organization#GO:0007005;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016216.1|UniProtKB=W5NH84 W5NH84 PTHR23326:SF3 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000002494.1|UniProtKB=W5M3H4 W5M3H4 PTHR46258:SF3 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22A localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000014773.1|UniProtKB=W5NC40 W5NC40 PTHR18916:SF77 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004782.1|UniProtKB=W5MBH6 W5MBH6 PTHR15427:SF2 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-3 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016689.1|UniProtKB=W5NJ20 W5NJ20 PTHR23113:SF178 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 LEPOC|Ensembl=ENSLOCG00000004175.1|UniProtKB=W5M9E4 W5M9E4 PTHR12247:SF130 POLYCOMB GROUP PROTEIN SAM DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009461.1|UniProtKB=W5MT44 W5MT44 PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008762.1|UniProtKB=W5MQK6 W5MQK6 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014892.1|UniProtKB=W5NCH7 W5NCH7 PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000005605.1|UniProtKB=W5MEG5 W5MEG5 PTHR12610:SF30 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 4 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004370.1|UniProtKB=W5MA12 W5MA12 PTHR44665:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002645.1|UniProtKB=W5M3Z5 W5M3Z5 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000018125.1|UniProtKB=W5NNL7 W5NNL7 PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 LEPOC|Ensembl=ENSLOCG00000008739.1|UniProtKB=W5MQH6 W5MQH6 FOXL3 PTHR11829:SF211 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000014587.1|UniProtKB=W5NBE1 W5NBE1 PTHR12547:SF130 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012886.1|UniProtKB=W5N5G2 W5N5G2 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000003611.1|UniProtKB=W5M7B9 W5M7B9 CNFN PTHR15907:SF26 DUF614 FAMILY PROTEIN-RELATED CORNIFELIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005613.1|UniProtKB=W5MEI6 W5MEI6 PTHR11863:SF106 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE-LIKE PROTEIN 2 steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;steroid biosynthetic process#GO:0006694;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013416.1|UniProtKB=W5N7J5 W5N7J5 PTHR45653:SF4 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000688.1|UniProtKB=W5LXA3 W5LXA3 BFAR PTHR15898:SF13 BIFUNCTIONAL APOPTOSIS REGULATOR BIFUNCTIONAL APOPTOSIS REGULATOR transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000013807.1|UniProtKB=W5N8R8 W5N8R8 PTHR15726:SF5 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 4 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of cell division#GO:0051302;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of cytokinesis#GO:0032465 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;midbody#GO:0030496;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell division site#GO:0032153;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011116.1|UniProtKB=W5MZ52 W5MZ52 SLC6A7 PTHR11616:SF231 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT PROLINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011704.1|UniProtKB=W5N179 W5N179 PTHR11360:SF14 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 5 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012764.1|UniProtKB=W5N4Z5 W5N4Z5 PTHR48097:SF9 L-THREONINE ALDOLASE-RELATED L-THREONINE ALDOLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aldolase#PC00044;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000013984.1|UniProtKB=W5N9C8 W5N9C8 PTHR44140:SF1 LD25575P DNAJ (HSP40) HOMOLOG, SUBFAMILY C, MEMBER 3B PRECURSOR protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011965.1|UniProtKB=W5N259 W5N259 PTHR15109:SF3 AGAP004327-PA PROTEIN FAM193B cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015188.1|UniProtKB=W5NDI3 W5NDI3 PTHR13817:SF27 TITIN MYOSIN-BINDING PROTEIN C, SLOW-TYPE sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001385.1|UniProtKB=W5LZP1 W5LZP1 PTHR10199:SF88 THROMBOSPONDIN CARTILAGE OLIGOMERIC MATRIX PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016319.1|UniProtKB=W5NHN6 W5NHN6 PTHR13578:SF11 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL2-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005781.1|UniProtKB=W5MF25 W5MF25 PTHR10183:SF30 CALPAIN CALPAIN-10 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000010727.1|UniProtKB=W5MXP8 W5MXP8 PTHR44663:SF2 JUNCTIONAL ADHESION MOLECULE B JUNCTIONAL ADHESION MOLECULE B cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017498.1|UniProtKB=W5NLU4 W5NLU4 PTHR45773:SF3 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 4 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005023.1|UniProtKB=W5MCE0 W5MCE0 PTHR14087:SF7 THYMOCYTE NUCLEAR PROTEIN 1 THYMOCYTE NUCLEAR PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013152.1|UniProtKB=W5N6E4 W5N6E4 PTHR22802:SF463 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014673.1|UniProtKB=W5NBQ6 W5NBQ6 PTHR10806:SF6 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 serine protease#PC00203;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 LEPOC|Ensembl=ENSLOCG00000002369.1|UniProtKB=W5M324 W5M324 PTHR44783:SF1 CXADR-LIKE MEMBRANE PROTEIN CXADR-LIKE MEMBRANE PROTEIN cell surface#GO:0009986;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000006.1|UniProtKB=W5LV49 W5LV49 PTHR10683:SF18 TRANSALDOLASE TRANSALDOLASE cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aldolase#PC00044;lyase#PC00144 Pentose phosphate pathway#P02762>Transaldolase#P03081 LEPOC|Ensembl=ENSLOCG00000000528.1|UniProtKB=W5LWS5 W5LWS5 PTHR16675:SF191 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, F10 ALPHA CHAIN-LIKE-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000006066.1|UniProtKB=W5MG15 W5MG15 PTHR10127:SF899 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ASTACIN-LIKE METALLOENDOPEPTIDASE-RELATED hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008956.1|UniProtKB=W5MRA7 W5MRA7 PTHR18947:SF36 HOOK PROTEINS PROTEIN HOOK HOMOLOG 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005391.1|UniProtKB=W5MDN7 W5MDN7 PTHR46484:SF1 SI:CH211-171H4.5-RELATED SCHWANN CELL MYELIN PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000013233.1|UniProtKB=W5N6P2 W5N6P2 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016538.1|UniProtKB=W5NIG7 W5NIG7 ARHGAP8 PTHR45808:SF4 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 8 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of localization#GO:0032879;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000017961.1|UniProtKB=W5NN55 W5NN55 GDPGP1 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006802.1|UniProtKB=W5MIL6 W5MIL6 PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN BLOC-2 COMPLEX MEMBER HPS5 pigmentation#GO:0043473;developmental pigmentation#GO:0048066 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008828.1|UniProtKB=W5MQT2 W5MQT2 PTHR24240:SF73 OPSIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002213.1|UniProtKB=W5M2I1 W5M2I1 PTHR22850:SF90 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000017427.1|UniProtKB=W5NLM3 W5NLM3 PTHR12002:SF112 CLAUDIN CLAUDIN-3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000010065.1|UniProtKB=W5MVB3 W5MVB3 PTHR46079:SF1 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4B cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;bicellular tight junction#GO:0005923;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000007459.1|UniProtKB=W5MKZ3 W5MKZ3 PTHR19143:SF31 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-4 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003833.1|UniProtKB=W5M866 W5M866 PTHR13609:SF11 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 1 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000111.1|UniProtKB=W5LVG7 W5LVG7 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013007.1|UniProtKB=W5N5X1 W5N5X1 PTHR12710:SF0 NUCLEAR PROTEIN LOCALIZATION 4 NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010062.1|UniProtKB=W5MV97 W5MV97 KIAA2026 PTHR31095:SF3 RIKEN CDNA 9930021J03 GENE RIKEN CDNA 9930021J03 GENE LEPOC|Ensembl=ENSLOCG00000014011.1|UniProtKB=W5N9G2 W5N9G2 PTHR10183:SF405 CALPAIN CALPAIN-5 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014600.1|UniProtKB=W5NBF7 W5NBF7 PTHR21016:SF7 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000016072.1|UniProtKB=W5NGP6 W5NGP6 PTHR12669:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 p53 pathway by glucose deprivation#P04397>4E-BP1#P04637;CCKR signaling map#P06959>4E-BP1#P07230;p38 MAPK pathway#P05918>4E-BP1#P06042 LEPOC|Ensembl=ENSLOCG00000007216.1|UniProtKB=W5MK25 W5MK25 PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 Wnt signaling pathway#P00057>alpha-catenin#P01471 LEPOC|Ensembl=ENSLOCG00000008266.1|UniProtKB=W5MNS4 W5MNS4 PTHR23235:SF145 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001113.1|UniProtKB=W5LYP4 W5LYP4 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011340.1|UniProtKB=W5MZX6 W5MZX6 PTHR22883:SF11 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC21 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010123.1|UniProtKB=W5MVJ2 W5MVJ2 PTHR10694:SF3 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5B histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000016128.1|UniProtKB=W5NGW3 W5NGW3 SAMD5 PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000002827.1|UniProtKB=W5M4M3 W5M4M3 PTHR10153:SF38 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;calmodulin binding#GO:0005516;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;protein binding#GO:0005515;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000017259.1|UniProtKB=W5NL38 W5NL38 PTHR10174:SF73 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-2 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;organelle organization#GO:0006996 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005211.1|UniProtKB=W5MD11 W5MD11 PTHR24061:SF441 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011397.1|UniProtKB=W5N056 W5N056 PTHR10589:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005378.1|UniProtKB=W5MDM8 W5MDM8 ASS1 PTHR11587:SF2 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;amide metabolic process#GO:0043603;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;alpha-amino acid biosynthetic process#GO:1901607;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 LEPOC|Ensembl=ENSLOCG00000003295.1|UniProtKB=W5M677 W5M677 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000012878.1|UniProtKB=W5N5H5 W5N5H5 ABCA5 PTHR19229:SF209 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006477.1|UniProtKB=W5MHG7 W5MHG7 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008674.1|UniProtKB=W5MQ87 W5MQ87 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007450.1|UniProtKB=W5MKX7 W5MKX7 PTHR18952:SF275 CARBONIC ANHYDRASE CARBONIC ANHYDRASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001295.1|UniProtKB=W5LZD9 W5LZD9 PTHR12181:SF62 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;lipid catabolic process#GO:0016042;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;response to insulin#GO:0032868;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;positive regulation of biosynthetic process#GO:0009891;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;glycerolipid biosynthetic process#GO:0045017;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;fatty acid catabolic process#GO:0009062;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004396.1|UniProtKB=W5MA49 W5MA49 PTHR10404:SF50 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE AMINOPEPTIDASE NAALADL1 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014126.1|UniProtKB=W5N9U3 W5N9U3 PTHR19282:SF380 TETRASPANIN TETRASPANIN-8 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007412.1|UniProtKB=W5MKT9 W5MKT9 PTHR22850:SF82 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP7 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005507.1|UniProtKB=W5ME35 W5ME35 PTHR12951:SF5 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG A lipid binding#GO:0008289;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;visual perception#GO:0007601;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;cytoskeleton-dependent cytokinesis#GO:0061640;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;cilium assembly#GO:0060271;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;positive regulation of macromolecule metabolic process#GO:0010604;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of endocytosis#GO:0045806;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cilium organization#GO:0044782;cell division#GO:0051301;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;developmental process#GO:0032502;transport#GO:0006810;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;organic substance transport#GO:0071702;mitotic cytokinesis#GO:0000281;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;negative regulation of cellular process#GO:0048523;cytokinesis#GO:0000910;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;multicellular organism development#GO:0007275;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;nervous system process#GO:0050877;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;positive regulation of protein metabolic process#GO:0051247;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of kinase activity#GO:0033674;sensory perception#GO:0007600;regulation of transferase activity#GO:0051338 spindle pole#GO:0000922;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;spindle#GO:0005819 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003760.1|UniProtKB=W5M7Z2 W5M7Z2 PTHR21119:SF8 C2 DOMAIN-CONTAINING PROTEIN PHOSPHOLIPID TRANSFER PROTEIN C2CD2L lipid transfer activity#GO:0120013;binding#GO:0005488;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 positive regulation of protein secretion#GO:0050714;regulation of signaling#GO:0023051;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;positive regulation of insulin secretion#GO:0032024;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;positive regulation of protein transport#GO:0051222;regulation of protein transport#GO:0051223;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;positive regulation of establishment of protein localization#GO:1904951;positive regulation of secretion#GO:0051047;positive regulation of transport#GO:0051050;regulation of cellular localization#GO:0060341;regulation of hormone levels#GO:0010817;positive regulation of cellular process#GO:0048522;positive regulation of hormone secretion#GO:0046887;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829;positive regulation of secretion by cell#GO:1903532;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177 LEPOC|Ensembl=ENSLOCG00000007700.1|UniProtKB=W5MLU2 W5MLU2 PTHR19308:SF7 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000014680.1|UniProtKB=W5NBR5 W5NBR5 PTHR48092:SF13 KNIRPS-RELATED PROTEIN-RELATED ANDROGEN RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;reproductive system development#GO:0061458;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;male sex differentiation#GO:0046661;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;developmental process involved in reproduction#GO:0003006;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>AR#P06774 LEPOC|Ensembl=ENSLOCG00000009259.1|UniProtKB=W5MSD4 W5MSD4 FAM83A PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83A-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000001363.1|UniProtKB=W5LZI5 W5LZI5 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001538.1|UniProtKB=W5M060 W5M060 ZMYND12 PTHR46533:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 LEPOC|Ensembl=ENSLOCG00000002048.1|UniProtKB=W5M1Y4 W5M1Y4 PTHR43740:SF2 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012671.1|UniProtKB=W5N4P5 W5N4P5 PTHR12444:SF1 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG A protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016508.1|UniProtKB=W5NID2 W5NID2 PTHR24240:SF0 OPSIN OPSIN-5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010974.1|UniProtKB=W5MYK5 W5MYK5 PTHR45655:SF10 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 88E lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000003138.1|UniProtKB=W5M5P8 W5M5P8 PTHR13317:SF4 TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006998.1|UniProtKB=W5MJC4 W5MJC4 PTHR46025:SF2 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-xylosyltransferase activity#GO:0035252;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017963.1|UniProtKB=W5NN57 W5NN57 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016896.1|UniProtKB=W5NJS6 W5NJS6 PTHR45632:SF29 LD33804P KELCH-LIKE PROTEIN 31 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011730.1|UniProtKB=W5N1B3 W5N1B3 PTHR11938:SF91 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FdxR#P04604 LEPOC|Ensembl=ENSLOCG00000006845.1|UniProtKB=W5MIT2 W5MIT2 PTHR23220:SF22 INTEGRIN ALPHA INTEGRIN ALPHA-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000003425.1|UniProtKB=W5M6P4 W5M6P4 PTHR24243:SF205 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN U RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001032.1|UniProtKB=W5LYF8 W5LYF8 PTHR12968:SF4 B9 DOMAIN-CONTAINING TECTONIC-LIKE COMPLEX MEMBER MKS1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013243.1|UniProtKB=W5N6Q7 W5N6Q7 PTHR43802:SF1 ENOYL-COA HYDRATASE IP11341P-RELATED lyase#PC00144;hydratase#PC00120 LEPOC|Ensembl=ENSLOCG00000007738.1|UniProtKB=W5MLZ7 W5MLZ7 PTHR10130:SF2 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008478.1|UniProtKB=W5MPK7 W5MPK7 PTHR13703:SF41 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 9 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 LEPOC|Ensembl=ENSLOCG00000014463.1|UniProtKB=W5NAZ1 W5NAZ1 PTHR10270:SF283 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-19A-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;head development#GO:0060322;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000015256.1|UniProtKB=W5NDR6 W5NDR6 PTHR45697:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017656.1|UniProtKB=W5NMA2 W5NMA2 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004946.1|UniProtKB=W5MC49 W5MC49 PTHR42881:SF4 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013172.1|UniProtKB=W5N6G4 W5N6G4 PTHR11691:SF62 TYPE I INTERFERON INTERFERON PHI 2-RELATED cytokine#PC00083;interferon superfamily#PC00127 LEPOC|Ensembl=ENSLOCG00000013790.1|UniProtKB=W5N8P8 W5N8P8 PTHR44554:SF1 LRP2-BINDING PROTEIN LRP2-BINDING PROTEIN LEPOC|Ensembl=ENSLOCG00000014725.1|UniProtKB=W5NBX2 W5NBX2 PTHR15074:SF6 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING PROTEIN 2 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007757.1|UniProtKB=W5MM17 W5MM17 PTHR13903:SF8 PIRIN-RELATED PIRIN transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012484.1|UniProtKB=W5N407 W5N407 PTHR24214:SF9 PDZ AND LIM DOMAIN PROTEIN ZASP LIM DOMAIN-BINDING PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006327.1|UniProtKB=W5MGX8 W5MGX8 PTHR12111:SF2 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2B-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003686.1|UniProtKB=W5M7L8 W5M7L8 PTHR13531:SF4 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 17B organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000004819.1|UniProtKB=W5MBM5 W5MBM5 PTHR12167:SF2 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>CNP#P06824;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06905;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06690 LEPOC|Ensembl=ENSLOCG00000013409.1|UniProtKB=W5N7C4 W5N7C4 PTHR23189:SF40 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15B-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014754.1|UniProtKB=W5NC08 W5NC08 PTHR19305:SF22 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000004090.1|UniProtKB=W5M945 W5M945 PTHR12207:SF8 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016518.1|UniProtKB=W5NIE4 W5NIE4 C6orf118 PTHR34916:SF1 GI:13385330 GI:13385330 LEPOC|Ensembl=ENSLOCG00000014985.1|UniProtKB=W5NCV1 W5NCV1 PTHR24416:SF131 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636;Angiogenesis#P00005>FGFR-1#P00186 LEPOC|Ensembl=ENSLOCG00000014201.1|UniProtKB=W5NA37 W5NA37 PTHR14383:SF1 SWAP-70 RECOMBINASE PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY D MEMBER 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007011.1|UniProtKB=W5MJE5 W5MJE5 PTHR12702:SF2 SEC15 EXOCYST COMPLEX COMPONENT 6 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018261.1|UniProtKB=W5NP03 W5NP03 PTHR22650:SF6 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IX Blood coagulation#P00011>GP IX#P00455 LEPOC|Ensembl=ENSLOCG00000002514.1|UniProtKB=W5M3I8 W5M3I8 MCIDAS PTHR13372:SF3 GEMININ MULTICILIN negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cell cycle#GO:0045786;regulation of DNA metabolic process#GO:0051052;negative regulation of metabolic process#GO:0009892;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018209.1|UniProtKB=W5NNV1 W5NNV1 PTHR26451:SF866 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010486.1|UniProtKB=W5MWU3 W5MWU3 FAM107A PTHR16768:SF3 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A ACTIN-ASSOCIATED PROTEIN FAM107A cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;synapse#GO:0045202;actin filament bundle#GO:0032432;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;cytoskeleton#GO:0005856;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000017194.1|UniProtKB=W5NKU2 W5NKU2 PTHR12479:SF5 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4A bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000604.1|UniProtKB=W5LX06 W5LX06 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016912.1|UniProtKB=W5NJV0 W5NJV0 PTHR12199:SF3 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 1 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014669.1|UniProtKB=W5NBQ0 W5NBQ0 PTHR12120:SF1 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of JNK cascade#GO:0046330;regulation of JNK cascade#GO:0046328;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008611.1|UniProtKB=W5MQ21 W5MQ21 PTHR23359:SF105 NUCLEOTIDE KINASE ADENYLATE KINASE 7 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000323.1|UniProtKB=W5LW42 W5LW42 PTHR24394:SF33 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8B transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009038.1|UniProtKB=W5MRK2 W5MRK2 PTHR47027:SF25 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000494.1|UniProtKB=W5LWN1 W5LWN1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007836.1|UniProtKB=W5MMA4 W5MMA4 PTHR12847:SF16 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;protein-containing complex#GO:0032991;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005347.1|UniProtKB=W5MDJ3 W5MDJ3 PTHR13412:SF0 T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG T-CELL IMMUNOMODULATORY PROTEIN LEPOC|Ensembl=ENSLOCG00000016854.1|UniProtKB=W5NJM6 W5NJM6 CSMD1 PTHR45656:SF3 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000004672.1|UniProtKB=W5MB35 W5MB35 PTHR10271:SF25 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 8 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;defense response to symbiont#GO:0140546 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001270.1|UniProtKB=W5LZ85 W5LZ85 PTHR31547:SF1 MULTIVESICULAR BODY SUBUNIT 12B MULTIVESICULAR BODY SUBUNIT 12B regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of ERBB signaling pathway#GO:1901184 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000004964.1|UniProtKB=W5MC61 W5MC61 PTHR16219:SF1 AUGMIN SUBUNIT 4 FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012288.1|UniProtKB=W5N3A9 W5N3A9 PTHR43561:SF3 FAMILY NOT NAMED HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000000328.1|UniProtKB=W5LW48 W5LW48 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014026.1|UniProtKB=W5N9I3 W5N9I3 PTHR10663:SF327 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007876.1|UniProtKB=W5MMG6 W5MMG6 PTHR15350:SF10 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 CONSTITUTIVE PHOTOMORPHOGENIC HOMOLOG SUBUNIT 7A protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017394.1|UniProtKB=W5NLJ0 W5NLJ0 GP5 PTHR24366:SF15 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN 2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000000398.1|UniProtKB=W5LWC6 W5LWC6 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000000451.1|UniProtKB=W5LWI5 W5LWI5 PTHR24208:SF118 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010044.1|UniProtKB=W5MV77 W5MV77 PTHR46939:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000010117.1|UniProtKB=W5MVG6 W5MVG6 PTHR46040:SF4 HIGH MOBILITY GROUP PROTEIN 2 HMG BOX DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010642.1|UniProtKB=W5MXC1 W5MXC1 PTHR35970:SF1 SODIUM CHANNEL AND CLATHRIN LINKER 1 SODIUM CHANNEL AND CLATHRIN LINKER 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006503.1|UniProtKB=W5MHJ6 W5MHJ6 PTHR15494:SF0 CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;sperm flagellum#GO:0036126 LEPOC|Ensembl=ENSLOCG00000004827.1|UniProtKB=W5MBP9 W5MBP9 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000008091.1|UniProtKB=W5MN74 W5MN74 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005576.1|UniProtKB=W5MEC9 W5MEC9 PTHR24095:SF126 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 LEPOC|Ensembl=ENSLOCG00000018326.1|UniProtKB=W5NP68 W5NP68 PTHR24369:SF213 ANTIGEN BSP, PUTATIVE-RELATED INSULIN LIKE GROWTH FACTOR BINDING PROTEIN ACID LABILE SUBUNIT cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010175.1|UniProtKB=W5MVP8 W5MVP8 PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006484.1|UniProtKB=W5MHH2 W5MHH2 PTHR24123:SF92 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN 50-LIKE scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004895.1|UniProtKB=W5MC04 W5MC04 PTHR24304:SF0 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7B1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001803.1|UniProtKB=W5M140 W5M140 PTHR16089:SF12 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016626.1|UniProtKB=W5NIT4 W5NIT4 PTHR48101:SF4 METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED METHYLMALONYL-COA MUTASE, MITOCHONDRIAL small molecule binding#GO:0036094;intramolecular transferase activity#GO:0016866;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;isomerase activity#GO:0016853 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 Methylmalonyl pathway#P02755>Methylmalonyl-CoA mutase#P03034;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA mutase#P03161 LEPOC|Ensembl=ENSLOCG00000016252.1|UniProtKB=W5NHD4 W5NHD4 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016668.1|UniProtKB=W5NIY3 W5NIY3 PTHR19432:SF35 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011072.1|UniProtKB=W5MZ08 W5MZ08 PTHR24020:SF49 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVIII) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000015904.1|UniProtKB=W5NG25 W5NG25 PTHR12430:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20 signal sequence binding#GO:0005048;protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001606.1|UniProtKB=W5M0E5 W5M0E5 DNAAF5 PTHR16216:SF2 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 5 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011125.1|UniProtKB=W5MZ59 W5MZ59 PTHR19346:SF2 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F4 LEPOC|Ensembl=ENSLOCG00000009969.1|UniProtKB=W5MUY1 W5MUY1 PTHR23065:SF16 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of dendrite development#GO:0050773;neurogenesis#GO:0022008;cell projection organization#GO:0030030;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;developmental process#GO:0032502;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of vesicle-mediated transport#GO:0060627;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of transport#GO:0051049;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of endocytosis#GO:0030100;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>PACSIN-1#P00802 LEPOC|Ensembl=ENSLOCG00000012675.1|UniProtKB=W5N4N6 W5N4N6 PTHR12113:SF12 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 2 signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000004602.1|UniProtKB=W5MAV6 W5MAV6 PTHR11743:SF12 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 2 voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000015955.1|UniProtKB=W5NG87 W5NG87 PTHR10104:SF6 STATHMIN STATHMIN-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 LEPOC|Ensembl=ENSLOCG00000007770.1|UniProtKB=W5MM27 W5MM27 PTHR11442:SF97 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA-D antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000004254.1|UniProtKB=W5M9M7 W5M9M7 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000015942.1|UniProtKB=W5NG69 W5NG69 PTHR24127:SF1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005598.1|UniProtKB=W5MEF6 W5MEF6 PTHR10288:SF97 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012779.1|UniProtKB=W5N513 W5N513 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003863.1|UniProtKB=W5M8B8 W5M8B8 PTHR47300:SF1 PROTEIN KASH5 PROTEIN KASH5 protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;meiosis I cell cycle process#GO:0061982;actin filament organization#GO:0007015;reproductive process#GO:0022414;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;spindle localization#GO:0051653;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;telomere localization#GO:0034397;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;actin cytoskeleton organization#GO:0030036;chromosome localization#GO:0050000 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;condensed chromosome#GO:0000793;organelle membrane#GO:0031090;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;nuclear membrane#GO:0031965;non-membrane-bounded organelle#GO:0043228;organelle outer membrane#GO:0031968;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;spindle#GO:0005819;envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle lumen#GO:0070013;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;outer membrane#GO:0019867;nuclear protein-containing complex#GO:0140513;synaptonemal complex#GO:0000795 LEPOC|Ensembl=ENSLOCG00000010560.1|UniProtKB=W5MX29 W5MX29 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000000368.1|UniProtKB=W5LW95 W5LW95 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009581.1|UniProtKB=W5MTK4 W5MTK4 PTHR16029:SF11 CENTROSOMAL PROTEIN OF 192 KDA CENTROSOMAL PROTEIN OF 192 KDA enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;macromolecule localization#GO:0033036;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;non-membrane-bounded organelle assembly#GO:0140694;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;protein localization to cytoskeleton#GO:0044380;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011884.1|UniProtKB=W5N1V0 W5N1V0 PTHR46171:SF2 GH10160P RING FINGER PROTEIN 44 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000010283.1|UniProtKB=W5MW60 W5MW60 PTHR18934:SF257 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX30 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000003299.1|UniProtKB=W5M683 W5M683 PTHR24346:SF44 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SET DOMAIN CONTAINING 6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002099.1|UniProtKB=W5M222 W5M222 PTHR23226:SF377 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014192.1|UniProtKB=W5NA24 W5NA24 PTHR11778:SF23 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, MITOCHONDRIAL cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010342.1|UniProtKB=W5MWC0 W5MWC0 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 HOMOLOG mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009081.1|UniProtKB=W5MRR0 W5MRR0 ERFE PTHR24019:SF13 ADIPOLIN ERYTHROFERRONE molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000006866.1|UniProtKB=W5MIU5 W5MIU5 PTHR11339:SF384 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006308.1|UniProtKB=W5MGV4 W5MGV4 PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;oxidative phosphorylation#GO:0006119;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013501.1|UniProtKB=W5N7P8 W5N7P8 PTHR11937:SF196 ACTIN ACTIN-LIKE PROTEIN 6B protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular protein-containing complex#GO:0140535;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006257.1|UniProtKB=W5MGP6 W5MGP6 PTHR23292:SF28 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR-LIKE cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013839.1|UniProtKB=W5N8V7 W5N8V7 PTHR28593:SF4 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000011560.1|UniProtKB=W5N0P0 W5N0P0 NEUROG1 PTHR19290:SF171 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;forebrain development#GO:0030900;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017915.1|UniProtKB=W5NN09 W5NN09 PTHR15503:SF39 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000009650.1|UniProtKB=W5MTT8 W5MTT8 PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 sulfur compound metabolic process#GO:0006790;positive regulation of catalytic activity#GO:0043085;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of molecular function#GO:0044093;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014061.1|UniProtKB=W5N9L8 W5N9L8 PTHR47403:SF2 LOC100145250 PROTEIN N-ACETYLTRANSFERASE 16,-LIKE LEPOC|Ensembl=ENSLOCG00000004637.1|UniProtKB=W5MAZ4 W5MAZ4 PTHR11254:SF293 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 SMAD binding#GO:0046332;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of BMP signaling pathway#GO:0030514;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of cellular response to growth factor stimulus#GO:0090287;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;TGF-beta signaling pathway#P00052>Smurfs#P01279 LEPOC|Ensembl=ENSLOCG00000007612.1|UniProtKB=W5MLH6 W5MLH6 PTHR19336:SF11 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN OF 57 KDA cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000009967.1|UniProtKB=W5MUX7 W5MUX7 PTHR23235:SF117 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CCKR signaling map#P06959>KLF4#P07227 LEPOC|Ensembl=ENSLOCG00000009225.1|UniProtKB=W5MSB4 W5MSB4 PTHR45622:SF11 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000479.1|UniProtKB=W5LWL8 W5LWL8 PTHR45134:SF5 OS08G0543275 PROTEIN OS08G0543275 PROTEIN LEPOC|Ensembl=ENSLOCG00000017286.1|UniProtKB=W5NL75 W5NL75 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016680.1|UniProtKB=W5NJ02 W5NJ02 PTHR16193:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 27 TETRATRICOPEPTIDE REPEAT PROTEIN 27 LEPOC|Ensembl=ENSLOCG00000009459.1|UniProtKB=W5MT39 W5MT39 PTHR18945:SF52 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422;Gonadotropin-releasing hormone receptor pathway#P06664>5-HT3AR#P06833 LEPOC|Ensembl=ENSLOCG00000003597.1|UniProtKB=W5M7E6 W5M7E6 PTHR11412:SF160 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-LIKE PROTEIN 1 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000005824.1|UniProtKB=W5MF76 W5MF76 PTHR21420:SF3 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cell communication#GO:0010646;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neurotic#P01115 LEPOC|Ensembl=ENSLOCG00000008504.1|UniProtKB=W5MPN8 W5MPN8 PTHR11866:SF3 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 LEPOC|Ensembl=ENSLOCG00000007811.1|UniProtKB=W5MM87 W5MM87 PTHR10901:SF9 TROPOMODULIN TROPOMODULIN-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006921.1|UniProtKB=W5MJ07 W5MJ07 PTHR38706:SF3 SI:CH211-198C19.1-RELATED SI:CH211-198C19.1 LEPOC|Ensembl=ENSLOCG00000006867.1|UniProtKB=W5MIU4 W5MIU4 PTHR21329:SF3 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001627.1|UniProtKB=W5M0I8 W5M0I8 PTHR10972:SF213 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 5 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;cortical endoplasmic reticulum#GO:0032541 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008218.1|UniProtKB=W5MNL9 W5MNL9 PTHR45710:SF31 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009660.1|UniProtKB=W5MTV3 W5MTV3 PTHR15923:SF0 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 2 anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005644.1|UniProtKB=W5MEL9 W5MEL9 PTHR10822:SF19 GLYPICAN GLYPICAN-5 regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of protein localization to membrane#GO:1905475;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;regulation of cellular localization#GO:0060341;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003467.1|UniProtKB=W5M6V1 W5M6V1 PTHR47977:SF16 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-39B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014738.1|UniProtKB=W5NBY8 W5NBY8 PTHR12400:SF55 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE A transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000014498.1|UniProtKB=W5NB33 W5NB33 PTHR10338:SF119 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013752.1|UniProtKB=W5N8J9 W5N8J9 PTHR15896:SF7 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED PROTEIN GOLM2 LEPOC|Ensembl=ENSLOCG00000015583.1|UniProtKB=W5NEY1 W5NEY1 PTHR24353:SF68 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>cGK 1#P07149;Endothelin signaling pathway#P00019>PKG#P00567 LEPOC|Ensembl=ENSLOCG00000005423.1|UniProtKB=W5MDW3 W5MDW3 PTHR42757:SF41 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEUROTRIMIN ISOFORM X1 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002997.1|UniProtKB=W5M574 W5M574 PTHR14503:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014151.1|UniProtKB=W5N9X6 W5N9X6 PTHR23122:SF14 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS1 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000200.1|UniProtKB=W5LVR6 W5LVR6 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007880.1|UniProtKB=W5MMG3 W5MMG3 PTHR12854:SF11 ATAXIN 2-RELATED ATAXIN-2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;non-membrane-bounded organelle assembly#GO:0140694;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017085.1|UniProtKB=W5NKF4 W5NKF4 PTHR45652:SF11 GLIAL FIBRILLARY ACIDIC PROTEIN NOTOCHORD GRANULAR SURFACE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000012844.1|UniProtKB=W5N5A2 W5N5A2 PTHR10996:SF230 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE B oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004888.1|UniProtKB=W5MBX8 W5MBX8 ZMIZ1 PTHR10782:SF7 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;ubiquitin-like protein ligase activity#GO:0061659;SUMO ligase activity#GO:0061665;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein sumoylation#GO:0016925;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007036.1|UniProtKB=W5MJG9 W5MJG9 PTHR11616:SF320 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NORADRENALINE TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>NET#P00064 LEPOC|Ensembl=ENSLOCG00000007085.1|UniProtKB=W5MJM0 W5MJM0 PTHR46166:SF1 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-D8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016386.1|UniProtKB=W5NHX6 W5NHX6 PTHR47992:SF105 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013801.1|UniProtKB=W5N8R1 W5N8R1 PTHR44019:SF2 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG A organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000018187.1|UniProtKB=W5NNS9 W5NNS9 OR56B1 PTHR26450:SF87 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009221.1|UniProtKB=W5MS93 W5MS93 PTHR12794:SF0 GEMIN2 GEM-ASSOCIATED PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015592.1|UniProtKB=W5NEZ0 W5NEZ0 PTHR24064:SF449 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 7-LIKE-RELATED secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013102.1|UniProtKB=W5N679 W5N679 PTHR10583:SF1 CHROMOGRANIN CHROMOGRANIN-A response to external biotic stimulus#GO:0043207;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;defense response#GO:0006952;regulation of protein transport#GO:0051223;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;regulation of hormone levels#GO:0010817;circulatory system process#GO:0003013;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;regulation of establishment of protein localization#GO:0070201;muscle system process#GO:0003012;heart process#GO:0003015;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CCKR signaling map#P06959>CHGA#G07271;CCKR signaling map#P06959>CHGA#G06978 LEPOC|Ensembl=ENSLOCG00000001335.1|UniProtKB=W5LZF8 W5LZF8 DOHH PTHR12697:SF5 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000020992.1|UniProtKB=Q8HQM5 Q8HQM5 ND4L PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010959.1|UniProtKB=W5MYI5 W5MYI5 PTHR24182:SF13 ANKYRIN REPEAT AND SOCS BOX CONTAINING 4 LD18443P LEPOC|Ensembl=ENSLOCG00000012587.1|UniProtKB=W5N4E0 W5N4E0 PTHR13037:SF11 FORMIN FORMIN-1 LEPOC|Ensembl=ENSLOCG00000012618.1|UniProtKB=W5N4H6 W5N4H6 PTHR15670:SF4 RHO GTPASE ACTIVATING PROTEIN 11A RHO GTPASE-ACTIVATING PROTEIN 11A nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000000048.1|UniProtKB=W5LVA0 W5LVA0 PTHR14519:SF8 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011890.1|UniProtKB=W5N1W3 W5N1W3 PTHR16228:SF23 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005765.1|UniProtKB=W5MF04 W5MF04 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 ZINC FINGER TRAF-TYPE-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001738.1|UniProtKB=W5M0V0 W5M0V0 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000009513.1|UniProtKB=W5MTC8 W5MTC8 PTHR13800:SF7 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 3 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013915.1|UniProtKB=W5N949 W5N949 PTHR11616:SF138 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell surface#GO:0009986;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004688.1|UniProtKB=W5MB64 W5MB64 PTHR11731:SF97 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10-LIKE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;regulation of metal ion transport#GO:0010959;organonitrogen compound metabolic process#GO:1901564;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011615.1|UniProtKB=W5N0W8 W5N0W8 PTHR48034:SF14 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG ALPHA nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017226.1|UniProtKB=W5NKZ7 W5NKZ7 PTHR35663:SF1 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED TESTIS DEVELOPMENT-RELATED PROTEIN developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004402.1|UniProtKB=W5MA50 W5MA50 PTHR11783:SF212 SULFOTRANSFERASE SULT SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003075.1|UniProtKB=W5M5I3 W5M5I3 PTHR23280:SF20 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 3 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 LEPOC|Ensembl=ENSLOCG00000004384.1|UniProtKB=W5MA27 W5MA27 PTHR20883:SF15 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014427.1|UniProtKB=W5NAV2 W5NAV2 PTHR45796:SF2 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX P3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000007329.1|UniProtKB=W5MKH4 W5MKH4 PTHR10913:SF78 FOLLISTATIN-RELATED AGRIN multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000008963.1|UniProtKB=W5MRB5 W5MRB5 PTHR12546:SF36 FER-1-LIKE FER-1-LIKE PROTEIN 4 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000006677.1|UniProtKB=W5MI74 W5MI74 PTHR10183:SF402 CALPAIN CALPAIN-5 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000014226.1|UniProtKB=W5NA59 W5NA59 PTHR13159:SF0 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD 6 HOMOLOG A cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001895.1|UniProtKB=W5M1F0 W5M1F0 PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015988.1|UniProtKB=W5NGC5 W5NGC5 PTHR15712:SF23 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT CONTAINING 10 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012766.1|UniProtKB=W5N4Z8 W5N4Z8 PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000847.1|UniProtKB=W5LXU4 W5LXU4 PTHR24031:SF762 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-II nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010097.1|UniProtKB=W5MVE6 W5MVE6 ASB9 PTHR24136:SF17 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 9 positive regulation of nitrogen compound metabolic process#GO:0051173;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000016375.1|UniProtKB=W5NHV9 W5NHV9 PTHR45716:SF1 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000003866.1|UniProtKB=W5M8A3 W5M8A3 PTHR14132:SF23 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transporter activity#GO:0032409 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009292.1|UniProtKB=W5MSH3 W5MSH3 PTHR24056:SF46 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;p53 pathway#P00059>Cdc2#P04634;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951 LEPOC|Ensembl=ENSLOCG00000015712.1|UniProtKB=W5NFD2 W5NFD2 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000014787.1|UniProtKB=W5NC51 W5NC51 PTHR10502:SF18 ANNEXIN ANNEXIN A2-RELATED lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000007551.1|UniProtKB=W5ML98 W5ML98 PTHR33524:SF2 C5ORF35 SET DOMAIN-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000009592.1|UniProtKB=W5MTK9 W5MTK9 PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to light stimulus#GO:0071482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;response to UV#GO:0009411;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006895.1|UniProtKB=W5MIX9 W5MIX9 PTHR24409:SF435 ZINC FINGER PROTEIN 142 CCCTC-BINDING FACTOR-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008558.1|UniProtKB=W5MPW8 W5MPW8 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003647.1|UniProtKB=W5M7I7 W5M7I7 PTHR46032:SF6 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosphingolipid biosynthetic process#GO:0006688;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008829.1|UniProtKB=W5MQT4 W5MQT4 GID4 PTHR15898:SF18 BIFUNCTIONAL APOPTOSIS REGULATOR GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006598.1|UniProtKB=W5MHX2 W5MHX2 PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 LEPOC|Ensembl=ENSLOCG00000006025.1|UniProtKB=W5MFW6 W5MFW6 PTHR24376:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 770 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009256.1|UniProtKB=W5MSD0 W5MSD0 PTHR10206:SF0 CATHELICIDIN CATHELICIDIN B1-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 LEPOC|Ensembl=ENSLOCG00000016657.1|UniProtKB=W5NIW7 W5NIW7 PTHR23055:SF79 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001095.1|UniProtKB=W5LYM8 W5LYM8 PTHR12207:SF31 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001800.1|UniProtKB=W5M164 W5M164 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014514.1|UniProtKB=W5NB57 W5NB57 PTHR43272:SF22 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 4 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;neurogenesis#GO:0022008;sulfur compound metabolic process#GO:0006790;developmental process#GO:0032502;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;neuron differentiation#GO:0030182;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;generation of neurons#GO:0048699;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000853.1|UniProtKB=W5LXU0 W5LXU0 PTHR24247:SF244 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012629.1|UniProtKB=W5N4I8 W5N4I8 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN ML43 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004707.1|UniProtKB=W5MB84 W5MB84 PTHR10985:SF150 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT 5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009621.1|UniProtKB=W5MTQ4 W5MTQ4 PTHR24223:SF166 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1-LIKE transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018045.1|UniProtKB=W5NND7 W5NND7 PTHR24232:SF95 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012450.1|UniProtKB=W5N3W7 W5N3W7 PTHR11849:SF13 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000015972.1|UniProtKB=W5NGA8 W5NGA8 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000010585.1|UniProtKB=W5MX72 W5MX72 PTHR11827:SF47 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;monoatomic cation transport#GO:0006812;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cell communication#GO:0007154;cellular component organization#GO:0016043;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;potassium ion import across plasma membrane#GO:1990573 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008582.1|UniProtKB=W5MPX9 W5MPX9 PTHR23291:SF16 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 LEPOC|Ensembl=ENSLOCG00000004678.1|UniProtKB=W5MB45 W5MB45 PTHR14568:SF9 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 2 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;lipid homeostasis#GO:0055088;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of lipid metabolic process#GO:0019216;chemical homeostasis#GO:0048878;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000004330.1|UniProtKB=W5M9W7 W5M9W7 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005417.1|UniProtKB=W5MDS9 W5MDS9 RPS20 PTHR11700:SF8 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER 40S RIBOSOMAL PROTEIN S20 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016789.1|UniProtKB=W5NJF8 W5NJF8 PTHR12634:SF15 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 2 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of phosphoprotein phosphatase activity#GO:0043666;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000015214.1|UniProtKB=W5NDL2 W5NDL2 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003950.1|UniProtKB=W5M8K7 W5M8K7 PTHR10605:SF11 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001294.1|UniProtKB=W5LZB0 W5LZB0 PTHR13809:SF11 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-3 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 LEPOC|Ensembl=ENSLOCG00000007077.1|UniProtKB=W5MJL7 W5MJL7 PTHR47970:SF12 KINESIN-LIKE PROTEIN KIF11 KINESIN FAMILY MEMBER 11 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;plus-end-directed microtubule motor activity#GO:0008574;ATP-dependent activity#GO:0140657 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;spindle elongation#GO:0051231;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011841.1|UniProtKB=W5N1Q1 W5N1Q1 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000003968.1|UniProtKB=W5M8N6 W5M8N6 PTHR24055:SF222 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 8 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;JNK cascade#GO:0007254;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>Jnk#P00951;TGF-beta signaling pathway#P00052>JNK#P01284;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>JNK1#P00221;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>JNK1-3#P00545;CCKR signaling map#P06959>MAPK8-10#P07090;FGF signaling pathway#P00021>JNK1-3#P00628;FAS signaling pathway#P00020>JNK#P00615;Oxidative stress response#P00046>JNK1/2#P01129;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>JNK#P00274;Toll receptor signaling pathway#P00054>JNK#P01375;B cell activation#P00010>Jnk#P00402;Parkinson disease#P00049>SAPK#P01219;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847;T cell activation#P00053>Jnk#P01336 LEPOC|Ensembl=ENSLOCG00000002602.1|UniProtKB=W5M3V4 W5M3V4 PTHR24133:SF33 ANKYRIN DOMAIN-CONTAINING ANKYRIN, ISOFORM B cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005439.1|UniProtKB=W5MDV3 W5MDV3 PTHR16056:SF2 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TESTIS-EXPRESSED PROTEIN 10 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000706.1|UniProtKB=W5LXC5 W5LXC5 PTHR11079:SF149 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;tRNA-specific adenosine deaminase activity#GO:0008251;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;adenosine to inosine editing#GO:0006382;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920 LEPOC|Ensembl=ENSLOCG00000001551.1|UniProtKB=W5M072 W5M072 PDPR PTHR13847:SF193 SARCOSINE DEHYDROGENASE-RELATED PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014429.1|UniProtKB=W5NAV0 W5NAV0 PTHR47136:SF1 SYNEMIN SYNEMIN structural constituent of muscle#GO:0008307;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488 multicellular organismal process#GO:0032501;nervous system process#GO:0050877;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;system process#GO:0003008;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;myofibril#GO:0030016;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008513.1|UniProtKB=W5MPS8 W5MPS8 PTHR16305:SF28 TESTICULAR SOLUBLE ADENYLYL CYCLASE GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Metabotropic glutamate receptor group III pathway#P00039>AC#P01043;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AC#P01082 LEPOC|Ensembl=ENSLOCG00000003140.1|UniProtKB=W5M5N9 W5M5N9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014265.1|UniProtKB=W5NAA2 W5NAA2 PTHR10687:SF5 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 5 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cytoplasmic vesicle membrane#GO:0030659 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002398.1|UniProtKB=W5M357 W5M357 PTHR11267:SF13 T-BOX PROTEIN-RELATED EOMESODERMIN HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;mononuclear cell differentiation#GO:1903131;mesoderm formation#GO:0001707;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;cell differentiation#GO:0030154;endoderm formation#GO:0001706;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;hemopoiesis#GO:0030097;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;immune effector process#GO:0002252;leukocyte activation#GO:0045321;gastrulation#GO:0007369;endoderm development#GO:0007492;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;lymphocyte activation#GO:0046649;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cell fate commitment#GO:0045165;cellular process#GO:0009987;cell activation involved in immune response#GO:0002263;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;T cell differentiation#GO:0030217;cell activation#GO:0001775;regulation of primary metabolic process#GO:0080090;mesoderm development#GO:0007498;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;lymphocyte differentiation#GO:0030098;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000014705.1|UniProtKB=W5NBU3 W5NBU3 STEEP1 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 STING ER EXIT PROTEIN endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 LEPOC|Ensembl=ENSLOCG00000016950.1|UniProtKB=W5NJZ9 W5NJZ9 PTHR11119:SF22 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 4 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007453.1|UniProtKB=W5MKY5 W5MKY5 PTHR45897:SF5 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;organic cation transport#GO:0015695;transport#GO:0006810;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010965.1|UniProtKB=W5MYJ6 W5MYJ6 PTHR45697:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011757.1|UniProtKB=W5N1E6 W5N1E6 PTHR16271:SF11 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000009563.1|UniProtKB=W5MTH7 W5MTH7 PTHR10472:SF1 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 2 catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001065.1|UniProtKB=W5LYJ0 W5LYJ0 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002526.1|UniProtKB=W5M3N4 W5M3N4 PTHR11849:SF209 ETS ETS TRANSLOCATION VARIANT 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167;Ras Pathway#P04393>Ets#P04563;VEGF signaling pathway#P00056>Ets#P01419;Angiogenesis#P00005>Ets#P00188 LEPOC|Ensembl=ENSLOCG00000006646.1|UniProtKB=W5MI38 W5MI38 PTHR24133:SF33 ANKYRIN DOMAIN-CONTAINING ANKYRIN, ISOFORM B cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015165.1|UniProtKB=W5NDF4 W5NDF4 PTHR12771:SF2 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015252.1|UniProtKB=W5NDQ9 W5NDQ9 PTHR12223:SF20 VESICULAR MANNOSE-BINDING LECTIN VIP36-LIKE PROTEIN carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488;monosaccharide binding#GO:0048029 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009066.1|UniProtKB=W5MRN7 W5MRN7 FAM174A PTHR28607:SF1 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174A LEPOC|Ensembl=ENSLOCG00000017224.1|UniProtKB=W5NKZ3 W5NKZ3 PTHR12353:SF3 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 2 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of system process#GO:0044057 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013882.1|UniProtKB=W5N917 W5N917 PTHR14164:SF12 PERICENTRIOLAR MATERIAL 1-RELATED PERICENTRIOLAR MATERIAL 1 PROTEIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009863.1|UniProtKB=W5MUJ7 W5MUJ7 PTHR48169:SF3 DED DOMAIN-CONTAINING PROTEIN CASP8 AND FADD LIKE APOPTOSIS REGULATOR LEPOC|Ensembl=ENSLOCG00000004155.1|UniProtKB=W5M9G3 W5M9G3 PTHR11733:SF141 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED MEMBRANE METALLO-ENDOPEPTIDASE-LIKE 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004903.1|UniProtKB=W5MBY5 W5MBY5 ETS2 PTHR11849:SF188 ETS PROTEIN C-ETS-2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003655.1|UniProtKB=W5M7J5 W5M7J5 PTHR24115:SF576 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF17 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012724.1|UniProtKB=W5N4V6 W5N4V6 PTHR11958:SF24 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 LEPOC|Ensembl=ENSLOCG00000013181.1|UniProtKB=W5N6H8 W5N6H8 PTHR24039:SF48 FIBRILLIN-RELATED FIBRILLIN-2 ISOFORM X1-RELATED extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000005819.1|UniProtKB=W5MF71 W5MF71 PTHR46838:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of lymphocyte migration#GO:2000401;positive regulation of protein modification process#GO:0031401;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;positive regulation of cytokine production#GO:0001819;defense response#GO:0006952;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;defense response to Gram-positive bacterium#GO:0050830;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;defense response to Gram-negative bacterium#GO:0050829;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of leukocyte migration#GO:0002687;negative regulation of multicellular organismal process#GO:0051241;positive regulation of biosynthetic process#GO:0009891;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of leukocyte activation#GO:0002694;regulation of cellular biosynthetic process#GO:0031326;positive regulation of cell migration#GO:0030335;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012102.1|UniProtKB=W5N2P3 W5N2P3 PTHR10048:SF30 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 LEPOC|Ensembl=ENSLOCG00000016528.1|UniProtKB=W5NIF7 W5NIF7 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;cellular response to stress#GO:0033554;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;mitochondria-associated endoplasmic reticulum membrane#GO:0044233;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003600.1|UniProtKB=W5M7B5 W5M7B5 PTHR15832:SF1 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;heterochromatin organization#GO:0070828;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014381.1|UniProtKB=W5NAP6 W5NAP6 PTHR11987:SF30 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8B transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003459.1|UniProtKB=W5M6V0 W5M6V0 PTHR46731:SF1 F-BOX ONLY PROTEIN 15 F-BOX ONLY PROTEIN 15 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000004395.1|UniProtKB=W5MA40 W5MA40 PTHR17550:SF7 E3 UBIQUITIN-PROTEIN LIGASE TTC3 RNA-BINDING PROTEIN 44 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009817.1|UniProtKB=W5MUE7 W5MUE7 POP1 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoribonuclease complex#GO:1902555;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;ribonuclease MRP complex#GO:0000172;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017404.1|UniProtKB=W5NLK0 W5NLK0 PTHR15573:SF0 G-PROTEIN COUPLED RECEPTOR 160-RELATED G-PROTEIN COUPLED RECEPTOR 160-RELATED receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004190.1|UniProtKB=W5M9E6 W5M9E6 PTHR24409:SF414 ZINC FINGER PROTEIN 142 WORNIU sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001601.1|UniProtKB=W5M0D4 W5M0D4 PTHR46677:SF1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 localization#GO:0051179;response to stimulus#GO:0050896;cellular localization#GO:0051641;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;cellular process#GO:0009987;cellular response to stress#GO:0033554;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018328.1|UniProtKB=W5NP70 W5NP70 PTHR23074:SF75 AAA DOMAIN-CONTAINING DYNEIN REGULATORY COMPLEX PROTEIN 11-RELATED pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000016526.1|UniProtKB=W5NIF4 W5NIF4 PTHR11267:SF83 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR T sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;mesoderm formation#GO:0001707;epithelium development#GO:0060429;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;gastrulation#GO:0007369;cellular developmental process#GO:0048869;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;mesoderm development#GO:0007498;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000010766.1|UniProtKB=W5MXT2 W5MXT2 PTHR15706:SF26 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008281.1|UniProtKB=W5MNU9 W5MNU9 PTHR23113:SF220 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017415.1|UniProtKB=W5NLL1 W5NLL1 ZBED1 PTHR46169:SF2 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A E3 SUMO-PROTEIN LIGASE ZBED1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007918.1|UniProtKB=W5MMK8 W5MMK8 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 transferase activity#GO:0016740;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000011706.1|UniProtKB=W5N181 W5N181 PTHR11276:SF28 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE LAMBDA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000010755.1|UniProtKB=W5MXR8 W5MXR8 PTHR14958:SF22 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD2 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001345.1|UniProtKB=W5LZH1 W5LZH1 PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002486.1|UniProtKB=W5M3G1 W5M3G1 PTHR16839:SF1 GALANIN GALANIN PEPTIDES LEPOC|Ensembl=ENSLOCG00000008774.1|UniProtKB=W5MQL7 W5MQL7 PTHR24068:SF72 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q-LIKE PROTEIN 1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010173.1|UniProtKB=W5MVP5 W5MVP5 PTHR18901:SF38 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000017237.1|UniProtKB=W5NL10 W5NL10 GEN1 PTHR11081:SF70 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE GEN HOMOLOG 1 DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000015209.1|UniProtKB=W5NDK9 W5NDK9 PTHR12639:SF6 VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000005830.1|UniProtKB=W5MFA0 W5MFA0 PTHR46182:SF1 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell motility#GO:0048870;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015569.1|UniProtKB=W5NEW0 W5NEW0 PTHR11547:SF52 ARGININE OR CREATINE KINASE CREATINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000010335.1|UniProtKB=W5MWB1 W5MWB1 PTHR11254:SF299 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000010685.1|UniProtKB=W5MXH8 W5MXH8 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017213.1|UniProtKB=W5NKX2 W5NKX2 ADI1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015260.1|UniProtKB=W5NDR9 W5NDR9 PTHR45476:SF3 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017878.1|UniProtKB=W5NMX2 W5NMX2 PTHR20937:SF4 IP14615P MESOGENIN-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 mesoderm formation#GO:0001707;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;gastrulation#GO:0007369;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;mesoderm development#GO:0007498;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001775.1|UniProtKB=W5M0Z4 W5M0Z4 PTHR10071:SF23 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;epithelium development#GO:0060429;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000277.1|UniProtKB=W5LVZ6 W5LVZ6 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED SI:CH211-113E8.5 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001831.1|UniProtKB=W5M163 W5M163 PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 LEPOC|Ensembl=ENSLOCG00000006660.1|UniProtKB=W5MI39 W5MI39 PTHR12127:SF6 MUCOLIPIN MUCOLIPIN-1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007049.1|UniProtKB=W5MJH2 W5MJH2 PTHR20952:SF0 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000014857.1|UniProtKB=W5NCD6 W5NCD6 PTHR24112:SF9 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001786.1|UniProtKB=W5M116 W5M116 PTHR43053:SF6 GLYCOSIDASE FAMILY 31 SITS-BINDING PROTEIN glucosidase#PC00108 LEPOC|Ensembl=ENSLOCG00000013474.1|UniProtKB=W5N7K3 W5N7K3 PTHR46492:SF1 DYNEIN ASSEMBLY FACTOR 4, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 4 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;protein-containing complex assembly#GO:0065003;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001100.1|UniProtKB=W5LYN0 W5LYN0 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000881.1|UniProtKB=W5LXX8 W5LXX8 PTHR43675:SF7 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 oxoacid metabolic process#GO:0043436;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;secondary metabolic process#GO:0019748;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014143.1|UniProtKB=W5N9W4 W5N9W4 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000014534.1|UniProtKB=W5NB78 W5NB78 PTHR11003:SF28 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 6 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008790.1|UniProtKB=W5MQP2 W5MQP2 PTHR15736:SF4 PROTEIN FAM131B-RELATED PROTEIN FAM131A LEPOC|Ensembl=ENSLOCG00000014526.1|UniProtKB=W5NB66 W5NB66 PTHR24180:SF39 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED PROTEASOME 26S SUBUNIT, NON-ATPASE 10 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;positive regulation of Wnt signaling pathway#GO:0030177;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of chromosome organization#GO:0033044;regulation of cell communication#GO:0010646;regulation of organelle organization#GO:0033043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000007889.1|UniProtKB=W5MMH9 W5MMH9 PTHR10117:SF56 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000012920.1|UniProtKB=W5N5K0 W5N5K0 BTBD1 PTHR24410:SF18 HL07962P-RELATED BTB DOMAIN CONTAINING 1 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010653.1|UniProtKB=W5MXE2 W5MXE2 PTHR45168:SF3 DNAJ HOMOLOG SUBFAMILY B MEMBER 2 DNAJ HEAT SHOCK PROTEIN FAMILY (HSP40) MEMBER B2 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017827.1|UniProtKB=W5NMS1 W5NMS1 PTHR23401:SF3 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 2 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209 neuron projection guidance#GO:0097485;head development#GO:0060322;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;distal axon#GO:0150034;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000009559.1|UniProtKB=W5MTI0 W5MTI0 PTHR16206:SF12 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006500.1|UniProtKB=W5MHJ8 W5MHJ8 PTHR10627:SF78 SCP160 PROTEIN BICAUDAL C HOMOLOG 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010275.1|UniProtKB=W5MW34 W5MW34 PTHR24020:SF37 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 2 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000015617.1|UniProtKB=W5NF20 W5NF20 PTHR24023:SF714 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;kidney development#GO:0001822;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000005505.1|UniProtKB=W5ME34 W5ME34 PTHR24412:SF398 KELCH PROTEIN KELCH-LIKE PROTEIN 30 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016229.1|UniProtKB=W5NHA2 W5NHA2 PTHR19282:SF51 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012190.1|UniProtKB=W5N2Y0 W5N2Y0 PTHR10638:SF4 COPPER AMINE OXIDASE RETINA-SPECIFIC COPPER AMINE OXIDASE cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 organonitrogen compound metabolic process#GO:1901564;amine metabolic process#GO:0009308;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 LEPOC|Ensembl=ENSLOCG00000018173.1|UniProtKB=W5NNR5 W5NNR5 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005477.1|UniProtKB=W5MDZ8 W5MDZ8 PTHR11076:SF33 DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER DNA POLYMERASE KAPPA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000651.1|UniProtKB=W5LX63 W5LX63 PTHR11716:SF4 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP 10 SECRETORY PHOSPHOLIPASE A2 cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000011512.1|UniProtKB=W5N0I9 W5N0I9 PTHR13723:SF158 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006270.1|UniProtKB=W5MGS0 W5MGS0 PTHR18929:SF58 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001061.1|UniProtKB=W5LYK4 W5LYK4 CDC25B PTHR10828:SF76 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle#GO:0045787;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001765.1|UniProtKB=W5M111 W5M111 PTHR46160:SF3 ALPHA-TECTORIN-RELATED ALPHA-TECTORIN LEPOC|Ensembl=ENSLOCG00000008644.1|UniProtKB=W5MQ48 W5MQ48 PTHR24112:SF9 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015281.1|UniProtKB=W5NDU7 W5NDU7 PTHR12301:SF5 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000000033.1|UniProtKB=W5LV80 W5LV80 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000359.1|UniProtKB=W5LW86 W5LW86 PTHR45134:SF5 OS08G0543275 PROTEIN OS08G0543275 PROTEIN LEPOC|Ensembl=ENSLOCG00000018296.1|UniProtKB=W5NP38 W5NP38 PTHR22750:SF20 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012830.1|UniProtKB=W5N582 W5N582 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;motile cilium#GO:0031514;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014469.1|UniProtKB=W5NB00 W5NB00 PTHR24166:SF28 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 46 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012306.1|UniProtKB=W5N3E0 W5N3E0 PTHR13024:SF1 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;lipid homeostasis#GO:0055088;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;basolateral plasma membrane#GO:0016323;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;basal plasma membrane#GO:0009925;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;basal part of cell#GO:0045178;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011261.1|UniProtKB=W5MZN0 W5MZN0 PTHR12422:SF3 GH09096P CYFIP-RELATED RAC1 INTERACTOR B regulation of multicellular organismal process#GO:0051239;regulation of cell-cell adhesion#GO:0022407;positive regulation of immune system process#GO:0002684;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of cellular process#GO:0050794;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 LEPOC|Ensembl=ENSLOCG00000011139.1|UniProtKB=W5MZ73 W5MZ73 PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000013304.1|UniProtKB=W5N6Y7 W5N6Y7 PTHR24229:SF90 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012666.1|UniProtKB=W5N4M8 W5N4M8 ACTR1A PTHR11937:SF370 ACTIN ALPHA-CENTRACTIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 LEPOC|Ensembl=ENSLOCG00000014058.1|UniProtKB=W5N9L7 W5N9L7 PTHR23339:SF123 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004774.1|UniProtKB=W5MBH5 W5MBH5 PTHR45716:SF3 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013738.1|UniProtKB=W5N8I0 W5N8I0 PTHR11949:SF22 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000008528.1|UniProtKB=W5MPS1 W5MPS1 PTHR43157:SF54 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 12-LIKE ISOFORM X1-RELATED glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003032.1|UniProtKB=W5M5B1 W5M5B1 TMEM200C PTHR31815:SF2 AGAP005329-PA TRANSMEMBRANE PROTEIN 200C LEPOC|Ensembl=ENSLOCG00000015149.1|UniProtKB=W5NDD3 W5NDD3 LSM1 PTHR15588:SF8 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000008542.1|UniProtKB=W5MPT4 W5MPT4 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014849.1|UniProtKB=W5NCC3 W5NCC3 PTHR24169:SF18 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR RELB sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;innate immune response#GO:0045087;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;canonical NF-kappaB signal transduction#GO:0007249;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;defense response to symbiont#GO:0140546;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;non-canonical NF-kappaB signal transduction#GO:0038061;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;defense response to other organism#GO:0098542;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297 LEPOC|Ensembl=ENSLOCG00000008181.1|UniProtKB=W5MNH4 W5MNH4 PTHR23503:SF99 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006177.1|UniProtKB=W5MGF5 W5MGF5 NOL4 PTHR12449:SF17 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000011782.1|UniProtKB=W5N1I0 W5N1I0 PTHR45652:SF18 GLIAL FIBRILLARY ACIDIC PROTEIN ALPHA-INTERNEXIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;synapse#GO:0045202;intermediate filament#GO:0005882;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;postsynapse#GO:0098794;cytoskeleton#GO:0005856 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000012650.1|UniProtKB=W5N4L7 W5N4L7 PTHR46049:SF2 AGAP003327-PA UNCONVENTIONAL MYOSIN-X microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;actin binding#GO:0003779 cellular localization#GO:0051641;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of anatomical structure morphogenesis#GO:0022603;transport#GO:0006810;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;regulation of filopodium assembly#GO:0051489;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 actin-based cell projection#GO:0098858;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;filopodium#GO:0030175 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000009382.1|UniProtKB=W5MST8 W5MST8 PTHR11829:SF195 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000012415.1|UniProtKB=W5N3S7 W5N3S7 PTHR13857:SF4 MRNA EDITING ENZYME C-U-EDITING ENZYME APOBEC-2 nucleic acid binding#GO:0003676;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;DNA modification#GO:0006304;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA demethylation#GO:0080111;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007996.1|UniProtKB=W5MMV1 W5MMV1 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;glycerol-3-phosphate metabolic process#GO:0006072;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 LEPOC|Ensembl=ENSLOCG00000012575.1|UniProtKB=W5N4C7 W5N4C7 PTHR10352:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 2 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000014044.1|UniProtKB=W5N9K2 W5N9K2 PTHR23257:SF717 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003978.1|UniProtKB=W5M8S6 W5M8S6 PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA-directed DNA polymerase activity#GO:0003887;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;exonuclease activity#GO:0004527;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000860.1|UniProtKB=W5LXV4 W5LXV4 PTHR11931:SF11 PHOSPHOGLYCERATE MUTASE BISPHOSPHOGLYCERATE MUTASE mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 LEPOC|Ensembl=ENSLOCG00000016688.1|UniProtKB=W5NJ10 W5NJ10 PTHR11834:SF2 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;embryonic organ development#GO:0048568;hippo signaling#GO:0035329;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003992.1|UniProtKB=W5M8S1 W5M8S1 PTHR12156:SF21 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 2 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;intracellular anatomical structure#GO:0005622 EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000015600.1|UniProtKB=W5NEZ7 W5NEZ7 PTHR10844:SF3 CAVEOLIN CAVEOLIN-2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 inorganic ion homeostasis#GO:0098771;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;response to insulin#GO:0032868;membrane organization#GO:0061024;response to peptide hormone#GO:0043434;plasma membrane organization#GO:0007009;developmental process#GO:0032502;endomembrane system organization#GO:0010256;cellular homeostasis#GO:0019725;cellular response to nitrogen compound#GO:1901699;intracellular calcium ion homeostasis#GO:0006874;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;membrane assembly#GO:0071709;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;negative regulation of cell population proliferation#GO:0008285;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;regulation of cell population proliferation#GO:0042127;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;intracellular chemical homeostasis#GO:0055082;regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;intracellular monoatomic cation homeostasis#GO:0030003;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873 plasma membrane raft#GO:0044853;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;Golgi apparatus#GO:0005794;cell junction#GO:0030054;caveola#GO:0005901;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;membrane raft#GO:0045121;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007028.1|UniProtKB=W5MJF0 W5MJF0 PTHR45664:SF3 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-A2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006690.1|UniProtKB=W5MI75 W5MI75 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;protein modification process#GO:0036211;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634 LEPOC|Ensembl=ENSLOCG00000017549.1|UniProtKB=W5NLZ5 W5NLZ5 RXFP3 PTHR10489:SF951 CELL ADHESION MOLECULE RELAXIN FAMILY PEPTIDE_INSL5 RECEPTOR 4 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016476.1|UniProtKB=W5NI94 W5NI94 PTHR45851:SF2 MYC PROTO-ONCOGENE N-MYC PROTO-ONCOGENE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000012778.1|UniProtKB=W5N518 W5N518 PTHR13318:SF47 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 20 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000003296.1|UniProtKB=W5M6F8 W5M6F8 PTHR23175:SF16 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 21 LEPOC|Ensembl=ENSLOCG00000002330.1|UniProtKB=W5M2Y7 W5M2Y7 PTHR47765:SF2 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN EXONUCLEASE MUT-7 HOMOLOG LEPOC|Ensembl=ENSLOCG00000007943.1|UniProtKB=W5MMN7 W5MMN7 PTHR10736:SF1 BESTROPHIN BESTROPHIN-2 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017597.1|UniProtKB=W5NM43 W5NM43 PTHR11953:SF2 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT MTR3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000009122.1|UniProtKB=W5MRX1 W5MRX1 WDR33 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015413.1|UniProtKB=W5NEB0 W5NEB0 COX20 PTHR31586:SF1 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002464.1|UniProtKB=W5M3E2 W5M3E2 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 motile cilium#GO:0031514;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226;vesicle#GO:0031982 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014389.1|UniProtKB=W5NAQ4 W5NAQ4 PTHR16043:SF1 DALRD3 PROTEIN DALR ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 3 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000002947.1|UniProtKB=W5M515 W5M515 PTHR10117:SF8 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;fertilization#GO:0009566;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;single fertilization#GO:0007338;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;reproduction#GO:0000003;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;sexual reproduction#GO:0019953;reproductive process#GO:0022414;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000007448.1|UniProtKB=W5MKX4 W5MKX4 PTHR46987:SF6 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-4 LEPOC|Ensembl=ENSLOCG00000000833.1|UniProtKB=W5LXS6 W5LXS6 PTHR19848:SF0 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004304.1|UniProtKB=W5M9T6 W5M9T6 PTHR47220:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001419.1|UniProtKB=W5LZR3 W5LZR3 PTHR45705:SF4 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005240.1|UniProtKB=W5MD52 W5MD52 PTHR11486:SF41 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000008851.1|UniProtKB=W5MQV9 W5MQV9 PTHR10165:SF94 LIPID PHOSPHATE PHOSPHATASE PHOSPHATIDIC ACID PHOSPHATASE TYPE 2D hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000886.1|UniProtKB=W5LXZ0 W5LXZ0 PTHR12002:SF27 CLAUDIN CLAUDIN-19 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000013309.1|UniProtKB=W5N704 W5N704 PTHR23180:SF197 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006561.1|UniProtKB=W5MHV0 W5MHV0 PTHR23317:SF78 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 7 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;neuron differentiation#GO:0030182;regulation of hydrolase activity#GO:0051336;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;regulation of GTPase activity#GO:0043087;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000008137.1|UniProtKB=W5MNC6 W5MNC6 PTHR24250:SF65 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000388.1|UniProtKB=W5LWB6 W5LWB6 PTHR13531:SF5 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 216 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000006360.1|UniProtKB=W5MH39 W5MH39 PTHR24028:SF11 CADHERIN-87A PROTOCADHERIN-15 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000009403.1|UniProtKB=W5MSW4 W5MSW4 FILIP1L PTHR23166:SF4 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN A-INTERACTING PROTEIN 1-LIKE LEPOC|Ensembl=ENSLOCG00000005637.1|UniProtKB=W5MEJ7 W5MEJ7 PTHR30616:SF2 UNCHARACTERIZED PROTEIN YFIH PURINE NUCLEOSIDE PHOSPHORYLASE LACC1 copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 LEPOC|Ensembl=ENSLOCG00000012479.1|UniProtKB=W5N412 W5N412 PTHR13414:SF9 HUEL-CATION TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003183.1|UniProtKB=W5M5V2 W5M5V2 PTHR11537:SF63 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000009387.1|UniProtKB=W5MSU3 W5MSU3 PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013338.1|UniProtKB=W5N738 W5N738 PTHR43977:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN LEPOC|Ensembl=ENSLOCG00000003234.1|UniProtKB=W5M626 W5M626 PTHR31198:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 84 CENTROSOMAL AT-AC SPLICING FACTOR LEPOC|Ensembl=ENSLOCG00000001073.1|UniProtKB=W5LYK5 W5LYK5 PTHR24072:SF136 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;postsynapse#GO:0098794;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane bounded cell projection#GO:0120025 small GTPase#PC00208 CCKR signaling map#P06959>CDC42-GTP#P07155;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Ras Pathway#P04393>Cdc42#P04569;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364;Integrin signalling pathway#P00034>Cdc42#P00938;Gonadotropin-releasing hormone receptor pathway#P06664>Cdc42#P06743;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;CCKR signaling map#P06959>CDC42-GDP#P07044;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;T cell activation#P00053>cdc42#P01333 LEPOC|Ensembl=ENSLOCG00000006682.1|UniProtKB=W5MI61 W5MI61 PTHR12550:SF18 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 2 protein binding#GO:0005515;methylated histone binding#GO:0035064;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004980.1|UniProtKB=W5MC82 W5MC82 PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Ubiquitin proteasome pathway#P00060>19S proteasome#P01494 LEPOC|Ensembl=ENSLOCG00000016259.1|UniProtKB=W5NHE4 W5NHE4 PTHR21723:SF2 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 N-TERMINAL DOMAIN-CONTAINING PROTEIN localization#GO:0051179;regulation of biological process#GO:0050789;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;chemical synaptic transmission#GO:0007268;macromolecule localization#GO:0033036;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267;protein localization#GO:0008104 somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008864.1|UniProtKB=W5MQY1 W5MQY1 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015936.1|UniProtKB=W5NG64 W5NG64 PTHR45796:SF1 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000017339.1|UniProtKB=W5NLD5 W5NLD5 PTHR10760:SF1 TORSIN TORSIN-4A envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004794.1|UniProtKB=W5MBJ0 W5MBJ0 PTHR24347:SF427 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK3 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013040.1|UniProtKB=W5N603 W5N603 PTHR21646:SF11 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 50 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013802.1|UniProtKB=W5N8R4 W5N8R4 TMEM164 PTHR20948:SF2 TRANSMEMBRANE PROTEIN 164 TRANSMEMBRANE PROTEIN 164 LEPOC|Ensembl=ENSLOCG00000005738.1|UniProtKB=W5MEX3 W5MEX3 PTHR24085:SF0 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003548.1|UniProtKB=W5M743 W5M743 PTHR48021:SF59 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 6 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009397.1|UniProtKB=W5MSW9 W5MSW9 PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;macroautophagy#GO:0016236;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;autophagy#GO:0006914;import into cell#GO:0098657 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;vesicle#GO:0031982;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;endomembrane system#GO:0012505;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;Ras Pathway#P04393>PI3K#P04567;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 LEPOC|Ensembl=ENSLOCG00000010082.1|UniProtKB=W5MVC1 W5MVC1 PTHR10485:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-A protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008462.1|UniProtKB=W5MPI8 W5MPI8 IQCG PTHR14871:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 9 DYNEIN REGULATORY COMPLEX PROTEIN 9 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 cytoplasm#GO:0005737;motile cilium#GO:0031514;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000010465.1|UniProtKB=W5MWS3 W5MWS3 PTHR46090:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;localization within membrane#GO:0051668;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 bounding membrane of organelle#GO:0098588;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001545.1|UniProtKB=W5M066 W5M066 PTHR43671:SF98 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK11 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002063.1|UniProtKB=W5M1Y5 W5M1Y5 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004053.1|UniProtKB=W5M8Y4 W5M8Y4 GGA2 PTHR45905:SF6 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015302.1|UniProtKB=W5NDZ4 W5NDZ4 PTHR45816:SF3 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR LEPOC|Ensembl=ENSLOCG00000013149.1|UniProtKB=W5N6D7 W5N6D7 MED11 PTHR22890:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mediator complex#GO:0016592;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007926.1|UniProtKB=W5MML4 W5MML4 PTHR22779:SF4 SD17342P TRANSMEMBRANE PROTEIN 170B regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011495.1|UniProtKB=W5N0G7 W5N0G7 PTHR23235:SF17 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000372.1|UniProtKB=W5LWA0 W5LWA0 VSTM2A PTHR12207:SF23 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2A cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004752.1|UniProtKB=W5MBE8 W5MBE8 KCNMA1 PTHR10027:SF33 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1-RELATED monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004519.1|UniProtKB=W5MAJ5 W5MAJ5 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005736.1|UniProtKB=W5MEX2 W5MEX2 PTHR45840:SF6 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 LEPOC|Ensembl=ENSLOCG00000009230.1|UniProtKB=W5MSA7 W5MSA7 PTHR11200:SF257 INOSITOL 5-PHOSPHATASE PHOSPHOINOSITIDE 5-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 Huntington disease#P00029>Synaptojanin#P00804 LEPOC|Ensembl=ENSLOCG00000011111.1|UniProtKB=W5MZ44 W5MZ44 PTHR15160:SF10 VON HIPPEL-LINDAU PROTEIN ZGC:158722 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004380.1|UniProtKB=W5MA29 W5MA29 PTHR24058:SF45 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 3 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;PML body#GO:0016605;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011067.1|UniProtKB=W5MYY1 W5MYY1 PTHR45850:SF2 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5-LIKE scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000989.1|UniProtKB=W5LYA7 W5LYA7 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000011.1|UniProtKB=W5LV55 W5LV55 PTHR14206:SF6 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015931.1|UniProtKB=W5NG62 W5NG62 PTHR22838:SF0 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 26 LEPOC|Ensembl=ENSLOCG00000011988.1|UniProtKB=W5N282 W5N282 PTHR12106:SF10 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS3 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011608.1|UniProtKB=W5N0V9 W5N0V9 PTHR22792:SF62 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015549.1|UniProtKB=W5NET4 W5NET4 PTHR10827:SF76 RETICULOCALBIN CALUMENIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010170.1|UniProtKB=W5MVN8 W5MVN8 PTHR45752:SF1 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 69 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014500.1|UniProtKB=W5NB41 W5NB41 PTHR23511:SF2 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000016715.1|UniProtKB=W5NJ47 W5NJ47 PTHR43762:SF8 L-GULONOLACTONE OXIDASE L-GULONOLACTONE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012041.1|UniProtKB=W5N2F6 W5N2F6 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 LEPOC|Ensembl=ENSLOCG00000004170.1|UniProtKB=W5M9C4 W5M9C4 PTHR12730:SF0 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;establishment of organelle localization#GO:0051656;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017112.1|UniProtKB=W5NKI6 W5NKI6 PTHR32261:SF4 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016816.1|UniProtKB=W5NJH3 W5NJH3 PTHR13906:SF7 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010421.1|UniProtKB=W5MWN7 W5MWN7 PTHR10170:SF10 HUNTINGTON DISEASE PROTEIN HUNTINGTIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Huntington disease#P00029>Htt#P00766;Huntington disease#P00029>PolyQ Htt#P00800;Huntington disease#P00029>PolyQ HTT#G01532;Huntington disease#P00029>Truncated Htt#P00761;Huntington disease#P00029>HTT#G01530 LEPOC|Ensembl=ENSLOCG00000007239.1|UniProtKB=W5MK51 W5MK51 PTHR24391:SF17 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06670;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06884;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#P06783 LEPOC|Ensembl=ENSLOCG00000005252.1|UniProtKB=W5MD67 W5MD67 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006813.1|UniProtKB=W5MIL9 W5MIL9 PTHR24253:SF159 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 42 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009125.1|UniProtKB=W5MRW8 W5MRW8 PTHR10151:SF107 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 3 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004849.1|UniProtKB=W5MBS6 W5MBS6 PTHR12784:SF6 STEERIN NEURON NAVIGATOR 2 system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000004002.1|UniProtKB=W5M8T6 W5M8T6 PTHR42918:SF9 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006591.1|UniProtKB=W5MHV3 W5MHV3 PTHR24073:SF1129 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 regulation of cell communication#GO:0010646;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;regulation of synaptic plasticity#GO:0048167;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;regulation of trans-synaptic signaling#GO:0099177;regulation of neuronal synaptic plasticity#GO:0048168;intracellular transport#GO:0046907;import into cell#GO:0098657 synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;endocytic vesicle#GO:0030139;cell projection#GO:0042995;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017936.1|UniProtKB=W5NN30 W5NN30 PTHR31366:SF2 UPF0739 PROTEIN C1ORF74 UPF0739 PROTEIN C1ORF74 LEPOC|Ensembl=ENSLOCG00000004030.1|UniProtKB=W5M8V6 W5M8V6 PTHR46189:SF2 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 regulation of cell communication#GO:0010646;regulation of response to external stimulus#GO:0032101;positive regulation of signal transduction#GO:0009967;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of defense response#GO:0031347;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;positive regulation of defense response#GO:0031349;positive regulation of signaling#GO:0023056;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010575.1|UniProtKB=W5MX47 W5MX47 PTHR35250:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 4 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 5 LEPOC|Ensembl=ENSLOCG00000013753.1|UniProtKB=W5N8K9 W5N8K9 PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001223.1|UniProtKB=W5LZ28 W5LZ28 PTHR13425:SF3 HEADCASE PROTEIN HEADCASE PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000006615.1|UniProtKB=W5MHY3 W5MHY3 PTHR11360:SF158 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 9 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002215.1|UniProtKB=W5M2H7 W5M2H7 PTHR11728:SF7 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;glycerol-3-phosphate metabolic process#GO:0006072;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009859.1|UniProtKB=W5MUJ2 W5MUJ2 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007403.1|UniProtKB=W5MKT6 W5MKT6 PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 regulation of transcription elongation by RNA polymerase II#GO:0034243;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA 3'-end processing#GO:0031124;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010882.1|UniProtKB=W5MY82 W5MY82 PTHR11384:SF59 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015986.1|UniProtKB=W5NGC4 W5NGC4 PTHR15032:SF4 N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000015568.1|UniProtKB=W5NEV5 W5NEV5 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003925.1|UniProtKB=W5M8H7 W5M8H7 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 53 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000010316.1|UniProtKB=W5MW83 W5MW83 PTHR21210:SF0 TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000002978.1|UniProtKB=W5M550 W5M550 PTHR14167:SF115 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 21 ISOFORM X1 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005045.1|UniProtKB=W5MCG1 W5MCG1 PTHR36876:SF1 UROTENSIN-2B UROTENSIN-2B LEPOC|Ensembl=ENSLOCG00000014519.1|UniProtKB=W5NB64 W5NB64 PTHR12612:SF9 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2-RELATED poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011386.1|UniProtKB=W5N039 W5N039 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000005236.1|UniProtKB=W5MD53 W5MD53 PTHR10816:SF10 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012593.1|UniProtKB=W5N4E4 W5N4E4 PTHR24169:SF9 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;B cell activation#P00010>NFkappaB#P00370;T cell activation#P00053>NFkappaB#P01298;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 LEPOC|Ensembl=ENSLOCG00000003228.1|UniProtKB=W5M602 W5M602 PTHR22923:SF69 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002579.1|UniProtKB=W5M3S7 W5M3S7 SUCLG1 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 LEPOC|Ensembl=ENSLOCG00000001649.1|UniProtKB=W5M0J8 W5M0J8 TNFRSF19 PTHR12120:SF1 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of JNK cascade#GO:0046330;regulation of JNK cascade#GO:0046328;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000018281.1|UniProtKB=W5NP23 W5NP23 PTHR24247:SF17 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1D signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 LEPOC|Ensembl=ENSLOCG00000009694.1|UniProtKB=W5MTY0 W5MTY0 PTHR24246:SF52 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013732.1|UniProtKB=W5N8H4 W5N8H4 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000016142.1|UniProtKB=W5NGY0 W5NGY0 PTHR13546:SF13 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85A LEPOC|Ensembl=ENSLOCG00000009110.1|UniProtKB=W5MRV3 W5MRV3 PTHR24126:SF3 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016452.1|UniProtKB=W5NI62 W5NI62 PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B LEPOC|Ensembl=ENSLOCG00000006483.1|UniProtKB=W5MHG9 W5MHG9 PTHR31185:SF0 FIN BUD INITIATION FACTOR FIBIN FIN BUD INITIATION FACTOR HOMOLOG LEPOC|Ensembl=ENSLOCG00000007390.1|UniProtKB=W5MKR4 W5MKR4 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000003626.1|UniProtKB=W5M7F3 W5M7F3 PTHR44188:SF3 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1 mitochondrial fusion#GO:0008053;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000003779.1|UniProtKB=W5M800 W5M800 PTHR10177:SF187 CYCLINS CYCLIN-I protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000014634.1|UniProtKB=W5NBK3 W5NBK3 PTHR24034:SF175 EGF-LIKE DOMAIN-CONTAINING PROTEIN COLLAGEN AND CALCIUM-BINDING EGF DOMAIN-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003360.1|UniProtKB=W5M6G3 W5M6G3 VSIG10 PTHR12231:SF222 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015918.1|UniProtKB=W5NG41 W5NG41 PTHR12290:SF12 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 3 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;regulation of cell communication#GO:0010646;regulation of transmembrane transport#GO:0034762;cellular localization#GO:0051641;transport#GO:0006810;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;intracellular transport#GO:0046907;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409 synapse#GO:0045202;somatodendritic compartment#GO:0036477;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell junction#GO:0030054;dendrite#GO:0030425;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;organelle#GO:0043226;coated vesicle#GO:0030135;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003483.1|UniProtKB=W5M6X9 W5M6X9 PTHR24124:SF7 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR DELTA regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002788.1|UniProtKB=W5M4H1 W5M4H1 PTHR15599:SF1 RTDR1 RADIAL SPOKE HEAD 14 HOMOLOG LEPOC|Ensembl=ENSLOCG00000002539.1|UniProtKB=W5M3N5 W5M3N5 PTHR10625:SF37 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 LEPOC|Ensembl=ENSLOCG00000009242.1|UniProtKB=W5MSB1 W5MSB1 PTHR24366:SF29 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 5 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000017953.1|UniProtKB=W5NN47 W5NN47 PTHR16840:SF8 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 1-LIKE LEPOC|Ensembl=ENSLOCG00000008090.1|UniProtKB=W5MN67 W5MN67 ATP5F1B PTHR15184:SF71 ATP SYNTHASE ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>F1 beta#P02794 LEPOC|Ensembl=ENSLOCG00000004212.1|UniProtKB=W5M9I1 W5M9I1 PTHR23136:SF10 TAX1-BINDING PROTEIN 3-RELATED ST6 N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 6 LEPOC|Ensembl=ENSLOCG00000016751.1|UniProtKB=W5NJ97 W5NJ97 PTHR24418:SF390 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000002818.1|UniProtKB=W5M4K7 W5M4K7 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 3 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000017204.1|UniProtKB=W5NKW1 W5NKW1 PTHR13769:SF1 APOLIPOPROTEIN B APOLIPOPROTEIN B-100 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000004529.1|UniProtKB=W5MAN3 W5MAN3 PTHR24416:SF90 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basal plasma membrane#GO:0009925;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466;Alzheimer disease-presenilin pathway#P00004>Erb-B4 N-terminal fragment#P00148;Alzheimer disease-presenilin pathway#P00004>Erb-B4#P00128;Alzheimer disease-presenilin pathway#P00004>Erb-B4 C-terminal fragment#P00163;Alzheimer disease-presenilin pathway#P00004>Erb-B4 transmembrane fragment#P00113 LEPOC|Ensembl=ENSLOCG00000008324.1|UniProtKB=W5MP03 W5MP03 PTHR10858:SF2 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-BETA hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;execution phase of apoptosis#GO:0097194;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;cellular component disassembly#GO:0022411;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000008133.1|UniProtKB=W5MNB7 W5MNB7 PTHR24372:SF72 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002652.1|UniProtKB=W5M414 W5M414 PTHR47464:SF3 MACOILIN MACOILIN-2 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000016849.1|UniProtKB=W5NJL6 W5NJL6 NOX3 PTHR11972:SF12 NADPH OXIDASE NADPH OXIDASE 3 oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009214.1|UniProtKB=W5MS83 W5MS83 PTHR14382:SF1 MDM2-BINDING PROTEIN MDM2-BINDING PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;cellular macromolecule localization#GO:0070727;protein localization to kinetochore#GO:0034501;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;protein localization to organelle#GO:0033365;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006159.1|UniProtKB=W5MGC9 W5MGC9 PTHR26451:SF905 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 2G3-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014607.1|UniProtKB=W5NBG8 W5NBG8 PTHR11451:SF51 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011671.1|UniProtKB=W5N134 W5N134 PTHR23503:SF25 SOLUTE CARRIER FAMILY 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009026.1|UniProtKB=W5MRI9 W5MRI9 PTHR24073:SF941 DRAB5-RELATED RAS-RELATED PROTEIN RAB-20 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000004911.1|UniProtKB=W5MBZ6 W5MBZ6 PTHR33443:SF30 ZGC:112980 SARCOSINE DEHYDROGENASE-2C PROTEIN LEPOC|Ensembl=ENSLOCG00000014711.1|UniProtKB=W5NBV8 W5NBV8 PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001302.1|UniProtKB=W5LZC3 W5LZC3 PTHR11850:SF97 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 3 head development#GO:0060322;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;embryonic organ development#GO:0048568;cell differentiation#GO:0030154;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;visual system development#GO:0150063;sensory system development#GO:0048880;generation of neurons#GO:0048699;sensory organ development#GO:0007423 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007108.1|UniProtKB=W5MJP9 W5MJP9 PTHR13409:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L51 LARGE RIBOSOMAL SUBUNIT PROTEIN ML51 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008936.1|UniProtKB=W5MR75 W5MR75 PTHR22811:SF117 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 7 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000001600.1|UniProtKB=W5M0D5 W5M0D5 AHSG PTHR13814:SF6 FETUIN ALPHA-2-HS-GLYCOPROTEIN peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000000573.1|UniProtKB=W5LWX5 W5LWX5 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005578.1|UniProtKB=W5MEC2 W5MEC2 PTHR10876:SF0 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007271.1|UniProtKB=W5MKA5 W5MKA5 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1 BETA CHAIN major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000016189.1|UniProtKB=W5NH51 W5NH51 PTHR10188:SF41 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;aspartate family amino acid metabolic process#GO:0009066;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012680.1|UniProtKB=W5N4P4 W5N4P4 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015496.1|UniProtKB=W5NEL3 W5NEL3 PTHR24055:SF146 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 12 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;p38 MAPK pathway#P05918>p38gamma#P06015;TGF-beta signaling pathway#P00052>P38#P01275;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>p38#P00562;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;B cell activation#P00010>p38#P00384;Oxidative stress response#P00046>p38#P01135;FGF signaling pathway#P00021>p38#P00644;Parkinson disease#P00049>SAPK#P01219 LEPOC|Ensembl=ENSLOCG00000016982.1|UniProtKB=W5NK33 W5NK33 PTHR24241:SF17 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1A RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;response to organic substance#GO:0010033;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013975.1|UniProtKB=W5N9C3 W5N9C3 PTHR11972:SF58 NADPH OXIDASE NADPH OXIDASE 5 oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010735.1|UniProtKB=W5MXP2 W5MXP2 PTHR21707:SF42 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016807.1|UniProtKB=W5NJG5 W5NJG5 PTHR10344:SF4 THYMIDYLATE KINASE UMP-CMP KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 LEPOC|Ensembl=ENSLOCG00000015777.1|UniProtKB=W5NFL4 W5NFL4 PTHR14710:SF2 GEM-ASSOCIATED PROTEIN 6 GEM-ASSOCIATED PROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000657.1|UniProtKB=W5LX75 W5LX75 PTHR11458:SF0 DELTA-AMINOLEVULINIC ACID DEHYDRATASE DELTA-AMINOLEVULINIC ACID DEHYDRATASE cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;hydro-lyase activity#GO:0016836;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 Heme biosynthesis#P02746>porphobilinogen synthase#P02979 LEPOC|Ensembl=ENSLOCG00000003492.1|UniProtKB=W5M6X8 W5M6X8 PTHR21017:SF11 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004000.1|UniProtKB=W5M8R3 W5M8R3 PTHR11767:SF100 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002364.1|UniProtKB=W5M327 W5M327 PTHR24289:SF19 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2 lyase activity#GO:0016829;steroid hydroxylase activity#GO:0008395;carbon-carbon lyase activity#GO:0016830;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;hormone metabolic process#GO:0042445;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000009245.1|UniProtKB=W5MSB5 W5MSB5 PTHR24208:SF116 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005232.1|UniProtKB=W5MD44 W5MD44 PTHR12035:SF107 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN MYELIN-ASSOCIATED GLYCOPROTEIN carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007042.1|UniProtKB=W5MJI2 W5MJI2 PTHR24416:SF505 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 LEPOC|Ensembl=ENSLOCG00000004301.1|UniProtKB=W5M9S9 W5M9S9 PTHR19338:SF0 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM13 LEPOC|Ensembl=ENSLOCG00000004978.1|UniProtKB=W5MCB0 W5MCB0 PTHR16515:SF64 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012829.1|UniProtKB=W5N579 W5N579 PTHR31183:SF1 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 53 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017934.1|UniProtKB=W5NN28 W5NN28 COA4 PTHR13639:SF2 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009121.1|UniProtKB=W5MRW3 W5MRW3 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007191.1|UniProtKB=W5MJZ3 W5MJZ3 PTHR24230:SF59 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 84 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015472.1|UniProtKB=W5NEI4 W5NEI4 PTHR31022:SF4 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of mitotic spindle organization#GO:0060236;regulation of cell cycle process#GO:0010564 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000014497.1|UniProtKB=W5NB36 W5NB36 PTHR46624:SF2 AGAP002036-PA SI:CH211-11N16.2-RELATED phosphatidylinositol-3-phosphate binding#GO:0032266;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;maintenance of location#GO:0051235;organelle organization#GO:0006996;cellular component organization#GO:0016043;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular process#GO:0009987;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008401.1|UniProtKB=W5MPA3 W5MPA3 PTHR13375:SF3 FMS INTERACTING PROTEIN THO COMPLEX SUBUNIT 5 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011870.1|UniProtKB=W5N1T4 W5N1T4 PTHR47091:SF2 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 2 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014983.1|UniProtKB=W5NCT6 W5NCT6 PTHR10522:SF0 GONADOLIBERIN PROGONADOLIBERIN-1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>GnRH#P06704 LEPOC|Ensembl=ENSLOCG00000000507.1|UniProtKB=W5LWQ0 W5LWQ0 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000017178.1|UniProtKB=W5NKS2 W5NKS2 PTHR11003:SF241 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 5 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008444.1|UniProtKB=W5MPG1 W5MPG1 PTHR16736:SF1 CORTEXIN-1-RELATED CORTEXIN-3 LEPOC|Ensembl=ENSLOCG00000017060.1|UniProtKB=W5NKC2 W5NKC2 ELOVL4 PTHR11157:SF12 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000016370.1|UniProtKB=W5NHV3 W5NHV3 PTHR21648:SF0 FLAGELLAR RADIAL SPOKE PROTEIN 3 RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000000295.1|UniProtKB=W5LW55 W5LW55 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000008629.1|UniProtKB=W5MQ31 W5MQ31 PTHR15503:SF39 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000000921.1|UniProtKB=W5LY52 W5LY52 PTHR12619:SF17 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000006096.1|UniProtKB=W5MG55 W5MG55 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000008135.1|UniProtKB=W5MNB5 W5MNB5 PTHR16119:SF17 TRANSMEMBRANE PROTEIN 144 TRANSMEMBRANE PROTEIN 144 LEPOC|Ensembl=ENSLOCG00000013957.1|UniProtKB=W5N9A0 W5N9A0 PTHR12547:SF177 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001408.1|UniProtKB=W5LZR6 W5LZR6 PTHR11566:SF225 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX-RELATED pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 response to external biotic stimulus#GO:0043207;response to virus#GO:0009615;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;receptor internalization#GO:0031623;membrane organization#GO:0061024;transport#GO:0006810;synaptic vesicle recycling#GO:0036465;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;defense response to virus#GO:0051607;defense response#GO:0006952;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;defense response to symbiont#GO:0140546;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;vesicle budding from membrane#GO:0006900;defense response to other organism#GO:0098542;organelle organization#GO:0006996;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 supramolecular complex#GO:0099080;synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003438.1|UniProtKB=W5M6R4 W5M6R4 PTHR11318:SF4 GUANYLIN FAMILY MEMBER GUANYLATE CYCLASE ACTIVATOR 2B molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014645.1|UniProtKB=W5NBM5 W5NBM5 PTHR10663:SF314 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006291.1|UniProtKB=W5MGU0 W5MGU0 PTHR15901:SF16 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN TESTICULAR HAPLOID EXPRESSED GENE PROTEIN LEPOC|Ensembl=ENSLOCG00000001867.1|UniProtKB=W5M1A7 W5M1A7 PTHR15175:SF4 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NADPH OXIDASE ACTIVATOR 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010262.1|UniProtKB=W5MW00 W5MW00 PTHR46253:SF3 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 3 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000008279.1|UniProtKB=W5MNU7 W5MNU7 PTHR24071:SF17 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;ribosome biogenesis#GO:0042254;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;protein-containing complex localization#GO:0031503;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012791.1|UniProtKB=W5N532 W5N532 PTHR11937:SF526 ACTIN ACTIN, CYTOPLASMIC 1-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000011418.1|UniProtKB=W5N075 W5N075 PTHR12329:SF12 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-folding chaperone binding#GO:0051087 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of biological quality#GO:0065008;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;negative regulation of cellular process#GO:0048523;negative regulation of apoptotic process#GO:0043066;protein stabilization#GO:0050821;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 LEPOC|Ensembl=ENSLOCG00000008631.1|UniProtKB=W5MQ32 W5MQ32 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001585.1|UniProtKB=W5M0B1 W5M0B1 PTHR46052:SF3 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Phosducin#P00758 LEPOC|Ensembl=ENSLOCG00000016978.1|UniProtKB=W5NK27 W5NK27 PTHR14353:SF9 MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE MARCKS MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014977.1|UniProtKB=W5NCT8 W5NCT8 PTHR46184:SF3 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXA microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 establishment or maintenance of cell polarity#GO:0007163;cellular developmental process#GO:0048869;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;epithelium development#GO:0060429;developmental process#GO:0032502;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;cell differentiation#GO:0030154;establishment of cell polarity#GO:0030010;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;establishment or maintenance of apical/basal cell polarity#GO:0035088;morphogenesis of an epithelium#GO:0002009;establishment or maintenance of bipolar cell polarity#GO:0061245 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;axonal growth cone#GO:0044295;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;distal axon#GO:0150034;cytoskeleton#GO:0005856;cell projection#GO:0042995;growth cone#GO:0030426;site of polarized growth#GO:0030427 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000013483.1|UniProtKB=W5N7M2 W5N7M2 FBF1 PTHR33689:SF1 FAS-BINDING FACTOR 1 FAS-BINDING FACTOR 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008101.1|UniProtKB=W5MN85 W5MN85 PTHR22804:SF41 AGGRECAN/VERSICAN PROTEOGLYCAN BREVICAN CORE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000016951.1|UniProtKB=W5NJZ6 W5NJZ6 PTHR11984:SF9 CONNEXIN GAP JUNCTION ALPHA-10 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000008798.1|UniProtKB=W5MQP9 W5MQP9 PTHR13231:SF3 MITOCHONDRIAL RIBOSOMAL PROTEIN S31 SMALL RIBOSOMAL SUBUNIT PROTEIN MS31 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016802.1|UniProtKB=W5NJF9 W5NJF9 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000018021.1|UniProtKB=W5NNB3 W5NNB3 FUT4 PTHR11929:SF132 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 4 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001163.1|UniProtKB=W5LYW3 W5LYW3 PTHR24103:SF573 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM62 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of NF-kappaB transcription factor activity#GO:0051092;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;defense response#GO:0006952;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of RNA metabolic process#GO:0051252;defense response to symbiont#GO:0140546;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008822.1|UniProtKB=W5MQU2 W5MQU2 PTHR45742:SF5 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 BETA CHAIN activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000013274.1|UniProtKB=W5N6V0 W5N6V0 GIYD1 PTHR20208:SF10 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 endodeoxyribonuclease#PC00093 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000007034.1|UniProtKB=W5MJK1 W5MJK1 DYNC2H1 PTHR45703:SF22 DYNEIN HEAVY CHAIN DYNEIN CYTOPLASMIC 2 HEAVY CHAIN 1 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005758.1|UniProtKB=W5MEZ2 W5MEZ2 PTHR13168:SF0 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 PDGF signaling pathway#P00047>c-Myc#P01172 LEPOC|Ensembl=ENSLOCG00000014628.1|UniProtKB=W5NBK2 W5NBK2 PTHR24299:SF8 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016020.1|UniProtKB=W5NGH3 W5NGH3 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 DYNEIN AXONEMAL ASSEMBLY FACTOR 10 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015720.1|UniProtKB=W5NFE3 W5NFE3 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011339.1|UniProtKB=W5MZX4 W5MZX4 PTHR13681:SF27 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL MOTOR NEURON PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;spliceosomal snRNP assembly#GO:0000387;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016087.1|UniProtKB=W5NGS1 W5NGS1 PTHR24115:SF398 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001844.1|UniProtKB=W5M171 W5M171 PTHR12080:SF134 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014118.1|UniProtKB=W5N9T6 W5N9T6 PTHR14944:SF3 RPA-RELATED PROTEIN RADX SI:CH73-71D17.2 LEPOC|Ensembl=ENSLOCG00000000135.1|UniProtKB=W5LVJ1 W5LVJ1 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 HOMOLOG mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016949.1|UniProtKB=W5NJZ3 W5NJZ3 PTHR15489:SF2 CASPASE 8 ASSOCIATED PROTEIN 2 CASP8-ASSOCIATED PROTEIN 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;PML body#GO:0016605 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006843.1|UniProtKB=W5MIS8 W5MIS8 PTHR11339:SF371 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006547.1|UniProtKB=W5MHP8 W5MHP8 PTHR12962:SF3 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED CALCIUM-REGULATED HEAT-STABLE PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011487.1|UniProtKB=W5N0F8 W5N0F8 PTHR12322:SF122 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sex differentiation#GO:0007548;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007973.1|UniProtKB=W5MMS6 W5MMS6 PTHR42938:SF22 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 LEPOC|Ensembl=ENSLOCG00000003680.1|UniProtKB=W5M7P3 W5M7P3 PTHR21646:SF32 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 33 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009883.1|UniProtKB=W5MUM7 W5MUM7 PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR LEPOC|Ensembl=ENSLOCG00000018301.1|UniProtKB=W5NP43 W5NP43 PTHR11214:SF361 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017214.1|UniProtKB=W5NKX4 W5NKX4 PTHR21581:SF6 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000005596.1|UniProtKB=W5MEE7 W5MEE7 PTHR36855:SF1 CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE PEROXISOME MEMBRANE ANCHOR PROTEIN PEX14P N-TERMINAL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017944.1|UniProtKB=W5NN38 W5NN38 PTHR11984:SF106 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000011108.1|UniProtKB=W5MZ39 W5MZ39 PTHR11502:SF6 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014333.1|UniProtKB=W5NAJ4 W5NAJ4 PTHR11036:SF14 SEMAPHORIN SEMAPHORIN-4B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009453.1|UniProtKB=W5MT32 W5MT32 PTHR11216:SF54 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;plasma membrane protein complex#GO:0098797;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;clathrin-coated pit#GO:0005905;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017291.1|UniProtKB=W5NL87 W5NL87 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006796.1|UniProtKB=W5MIK5 W5MIK5 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000011943.1|UniProtKB=W5N230 W5N230 PTHR46538:SF1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000009365.1|UniProtKB=W5MSR0 W5MSR0 PTHR31958:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 LEPOC|Ensembl=ENSLOCG00000017804.1|UniProtKB=W5NMP9 W5NMP9 PTHR23430:SF137 HISTONE H2A HISTONE H2A TYPE 1-A nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009872.1|UniProtKB=W5MUK8 W5MUK8 PTHR23409:SF19 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 LEPOC|Ensembl=ENSLOCG00000005460.1|UniProtKB=W5MDX6 W5MDX6 PTHR24418:SF438 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>Abl#P00946;Axon guidance mediated by Slit/Robo#P00008>Abl#P00347 LEPOC|Ensembl=ENSLOCG00000002148.1|UniProtKB=W5M291 W5M291 PTHR24100:SF145 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000018190.1|UniProtKB=W5NNT2 W5NNT2 PTHR19372:SF7 SULFITE REDUCTASE SULFITE OXIDASE, MITOCHONDRIAL tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015220.1|UniProtKB=W5NDM5 W5NDM5 PTHR11475:SF63 OXIDASE/PEROXIDASE EOSINOPHIL PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016079.1|UniProtKB=W5NGQ4 W5NGQ4 PTHR12989:SF10 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003142.1|UniProtKB=W5M5P5 W5M5P5 PTHR28593:SF2 METEORIN-LIKE PROTEIN METEORIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;gliogenesis#GO:0042063;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003627.1|UniProtKB=W5M7E8 W5M7E8 PTHR10760:SF14 TORSIN TORSIN-1B kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;nuclear envelope organization#GO:0006998;nuclear membrane organization#GO:0071763 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011862.1|UniProtKB=W5N1V6 W5N1V6 PTHR45857:SF2 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cell shape#GO:0008360;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012019.1|UniProtKB=W5N2C3 W5N2C3 PTHR46925:SF1 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED NEUROMEDIN-K RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;positive regulation of locomotion#GO:0040017;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;sperm flagellum#GO:0036126;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003083.1|UniProtKB=W5M5H5 W5M5H5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006743.1|UniProtKB=W5MID9 W5MID9 PTHR10807:SF37 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 12 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000002927.1|UniProtKB=W5M4Y6 W5M4Y6 GMPR PTHR43170:SF3 GMP REDUCTASE GMP REDUCTASE 1 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001921.1|UniProtKB=W5M1G8 W5M1G8 PTHR11486:SF30 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;dorsal/ventral pattern formation#GO:0009953;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;regionalization#GO:0003002;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;generation of neurons#GO:0048699;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000013649.1|UniProtKB=W5N892 W5N892 TENM3 PTHR11219:SF65 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-3 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000009037.1|UniProtKB=W5MRK8 W5MRK8 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular catabolic process#GO:0031330;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;heterochromatin organization#GO:0070828;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008532.1|UniProtKB=W5MPS3 W5MPS3 PTHR11383:SF3 NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13 NAD(P)H PYROPHOSPHATASE NUDT13, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000008316.1|UniProtKB=W5MNZ3 W5MNZ3 GABRG3 PTHR18945:SF195 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007404.1|UniProtKB=W5MKS8 W5MKS8 EIF3G PTHR10352:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000015623.1|UniProtKB=W5NF23 W5NF23 PTHR12113:SF10 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 4 signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010893.1|UniProtKB=W5MY94 W5MY94 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005171.1|UniProtKB=W5MCW9 W5MCW9 PTHR45781:SF4 AGAP000281-PA THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000007391.1|UniProtKB=W5MKQ7 W5MKQ7 PTHR23235:SF26 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000629.1|UniProtKB=W5LX39 W5LX39 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014576.1|UniProtKB=W5NBD6 W5NBD6 THSD4 PTHR13723:SF319 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE THROMBOSPONDIN TYPE 1 DOMAIN CONTAINING 4 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009611.1|UniProtKB=W5MTN4 W5MTN4 PTHR11753:SF4 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX SUBUNIT SIGMA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000014185.1|UniProtKB=W5NA12 W5NA12 PTHR46680:SF1 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR ALPHA NF-kappaB binding#GO:0051059;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 immune response-regulating signaling pathway#GO:0002764;cellular localization#GO:0051641;activation of immune response#GO:0002253;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;cell communication#GO:0007154;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;macromolecule localization#GO:0033036;pattern recognition receptor signaling pathway#GO:0002221;toll-like receptor 4 signaling pathway#GO:0034142;positive regulation of response to stimulus#GO:0048584;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833;negative regulation of DNA-binding transcription factor activity#GO:0043433;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;T cell activation#P00053>I kappa B#P01323;CCKR signaling map#P06959>IKBalpha#P07053;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IkappaB#P00857;Toll receptor signaling pathway#P00054>IkappaB#P01338;Apoptosis signaling pathway#P00006>IkappaB#P00292;B cell activation#P00010>I kappa B#P00392 LEPOC|Ensembl=ENSLOCG00000017096.1|UniProtKB=W5NKG7 W5NKG7 COQ3 PTHR43464:SF19 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013400.1|UniProtKB=W5N7B1 W5N7B1 PTHR13622:SF8 THIAMIN PYROPHOSPHOKINASE THIAMIN PYROPHOSPHOKINASE 1 kinase#PC00137 Thiamin metabolism#P02780>Thiamine kinase#P03176 LEPOC|Ensembl=ENSLOCG00000001971.1|UniProtKB=W5M1M8 W5M1M8 PTHR11644:SF24 CYTIDINE DEAMINASE CYTIDINE DEAMINASE cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;deaminase activity#GO:0019239;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011505.1|UniProtKB=W5N0H6 W5N0H6 PTHR32337:SF2 NUCLEOLAR PROTEIN 7 NUCLEOLAR PROTEIN 7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014355.1|UniProtKB=W5NAL9 W5NAL9 PTHR23288:SF12 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL2 ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011060.1|UniProtKB=W5MYX2 W5MYX2 PTHR17609:SF2 HMG DOMAIN-CONTAINING PROTEIN 3 HMG DOMAIN-CONTAINING PROTEIN 3 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000013736.1|UniProtKB=W5N8I3 W5N8I3 PTHR10155:SF5 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 7 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 LEPOC|Ensembl=ENSLOCG00000004024.1|UniProtKB=W5M8V0 W5M8V0 PTHR11266:SF80 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PEROXISOMAL MEMBRANE PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013860.1|UniProtKB=W5N8Y4 W5N8Y4 PTHR46269:SF1 EPIPHYCAN-RELATED MIMECAN system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;skeletal system development#GO:0001501;tissue development#GO:0009888;bone development#GO:0060348 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013806.1|UniProtKB=W5N8S1 W5N8S1 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015952.1|UniProtKB=W5NG89 W5NG89 PTHR13239:SF6 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012512.1|UniProtKB=W5N451 W5N451 PTHR14682:SF1 KATNB1-LIKE PROTEIN 1 KATNB1-LIKE PROTEIN 1 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011039.1|UniProtKB=W5MYT5 W5MYT5 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009759.1|UniProtKB=W5MU62 W5MU62 PTHR11153:SF3 SIDEROFLEXIN SIDEROFLEXIN-4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016250.1|UniProtKB=W5NHE8 W5NHE8 PTHR32170:SF3 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 peptidase activator activity#GO:0016504;proteasome binding#GO:0070628;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001211.1|UniProtKB=W5LZ06 W5LZ06 PTHR46334:SF1 COSTARS FAMILY PROTEIN ABRACL COSTARS FAMILY PROTEIN ABRACL biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000006490.1|UniProtKB=W5MHI2 W5MHI2 PTHR24068:SF63 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000010848.1|UniProtKB=W5MY38 W5MY38 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014742.1|UniProtKB=W5NBZ1 W5NBZ1 PTHR24073:SF315 DRAB5-RELATED RAS-RELATED PROTEIN RAB-7L1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014805.1|UniProtKB=W5NC69 W5NC69 PTHR10237:SF14 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN MYND-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004803.1|UniProtKB=W5MBK2 W5MBK2 PTHR24334:SF3 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013716.1|UniProtKB=W5N8F4 W5N8F4 PTHR23235:SF44 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004297.1|UniProtKB=W5M9S5 W5M9S5 PTHR24006:SF687 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002915.1|UniProtKB=W5M4X3 W5M4X3 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009595.1|UniProtKB=W5MTL9 W5MTL9 PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003179.1|UniProtKB=W5M5U7 W5M5U7 PTHR12173:SF3 GDNF SUBFAMILY OF TGF-BETA FAMILY NEURTURIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neurotrophic factor#PC00163;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000010341.1|UniProtKB=W5MWD4 W5MWD4 PTHR23023:SF204 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003211.1|UniProtKB=W5M5Y7 W5M5Y7 PTHR11414:SF21 CYSTATIN FAMILY MEMBER CYSTATIN 14A, TANDEM DUPLICATE 1-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002457.1|UniProtKB=W5M3D5 W5M3D5 PTHR24345:SF42 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;mitotic spindle organization#GO:0007052;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;microtubule cytoskeleton organization involved in mitosis#GO:1902850;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;intracellular signal transduction#GO:0035556;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;cellular response to stimulus#GO:0051716;Golgi organization#GO:0007030;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cell communication#GO:0007154;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003167.1|UniProtKB=W5M5T3 W5M5T3 PTHR22106:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001599.1|UniProtKB=W5M0F6 W5M0F6 PTHR47735:SF4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>K+ channel#P01070 LEPOC|Ensembl=ENSLOCG00000017616.1|UniProtKB=W5NM62 W5NM62 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003034.1|UniProtKB=W5M5C4 W5M5C4 PTHR10502:SF26 ANNEXIN ANNEXIN A5 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06684;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#P06814;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06897 LEPOC|Ensembl=ENSLOCG00000007143.1|UniProtKB=W5MJT6 W5MJT6 PTHR31463:SF4 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;defense response#GO:0006952 LEPOC|Ensembl=ENSLOCG00000016823.1|UniProtKB=W5NJI7 W5NJI7 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012284.1|UniProtKB=W5N3B1 W5N3B1 PTHR13246:SF1 ENDO BETA N-ACETYLGLUCOSAMINIDASE CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010481.1|UniProtKB=W5MWU0 W5MWU0 PTHR22923:SF96 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012693.1|UniProtKB=W5N4R0 W5N4R0 ARL3 PTHR45697:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008648.1|UniProtKB=W5MQ59 W5MQ59 PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB mitotic cytokinesis#GO:0000281;cell division#GO:0051301;mitotic cell cycle#GO:0000278;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cytokinesis#GO:0000910 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010503.1|UniProtKB=W5MWW5 W5MWW5 PTHR23192:SF8 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001947.1|UniProtKB=W5M1K9 W5M1K9 PTHR31131:SF2 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000005896.1|UniProtKB=W5MFG5 W5MFG5 PTHR23267:SF189 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 3 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009276.1|UniProtKB=W5MSF5 W5MSF5 PTHR11848:SF117 TGF-BETA FAMILY INHIBIN ALPHA CHAIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inha#P06855 LEPOC|Ensembl=ENSLOCG00000008536.1|UniProtKB=W5MPS9 W5MPS9 PTHR13056:SF0 VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008059.1|UniProtKB=W5MN40 W5MN40 PTHR13593:SF131 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 LEPOC|Ensembl=ENSLOCG00000014206.1|UniProtKB=W5NA47 W5NA47 PTHR42776:SF16 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008392.1|UniProtKB=W5MP94 W5MP94 PTHR45720:SF4 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 1 voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003081.1|UniProtKB=W5M5G9 W5M5G9 PTHR46061:SF2 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 LEPOC|Ensembl=ENSLOCG00000004700.1|UniProtKB=W5MB76 W5MB76 PTHR24058:SF12 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006103.1|UniProtKB=W5MG62 W5MG62 PTHR23267:SF189 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 3 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000408.1|UniProtKB=W5LWE4 W5LWE4 PTHR24416:SF370 TYROSINE-PROTEIN KINASE RECEPTOR HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to endogenous stimulus#GO:0009719;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018324.1|UniProtKB=W5NP66 W5NP66 TMEM74 PTHR16125:SF3 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74 LEPOC|Ensembl=ENSLOCG00000002857.1|UniProtKB=W5M4R9 W5M4R9 PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014540.1|UniProtKB=W5NB91 W5NB91 PTHR24115:SF445 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF7 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000010752.1|UniProtKB=W5MXR3 W5MXR3 PTHR21555:SF0 SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN LEPOC|Ensembl=ENSLOCG00000011791.1|UniProtKB=W5N1I4 W5N1I4 PTHR24366:SF57 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT, IG-LIKE AND TRANSMEMBRANE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000003568.1|UniProtKB=W5M768 W5M768 PTHR23136:SF11 TAX1-BINDING PROTEIN 3-RELATED ST6 N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 5 LEPOC|Ensembl=ENSLOCG00000010502.1|UniProtKB=W5MWW8 W5MWW8 PTHR24347:SF197 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016551.1|UniProtKB=W5NII2 W5NII2 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001202.1|UniProtKB=W5LYZ8 W5LYZ8 PTHR11955:SF96 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000012018.1|UniProtKB=W5N2C6 W5N2C6 PTHR15228:SF19 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 24 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 negative regulation of biological process#GO:0048519;regulation of plasma membrane bounded cell projection assembly#GO:0120032;epithelium development#GO:0060429;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;activation of GTPase activity#GO:0090630;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;wound healing#GO:0042060;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;negative regulation of small GTPase mediated signal transduction#GO:0051058;regulation of hydrolase activity#GO:0051336;negative regulation of cellular component organization#GO:0051129;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;negative regulation of signaling#GO:0023057;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;negative regulation of signal transduction#GO:0009968;cell migration#GO:0016477 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000010612.1|UniProtKB=W5MX97 W5MX97 PTHR45678:SF13 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER: GLUTAMATE), MEMBER 22-RELATED L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;acidic amino acid transmembrane transporter activity#GO:0015172 cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;respiratory electron transport chain#GO:0022904;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007637.1|UniProtKB=W5MLK8 W5MLK8 PTHR12001:SF69 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;cellular lipid metabolic process#GO:0044255;isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 LEPOC|Ensembl=ENSLOCG00000000327.1|UniProtKB=W5LW44 W5LW44 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001540.1|UniProtKB=W5M058 W5M058 PTHR46940:SF1 NKAP DOMAIN-CONTAINING 1 NKAP DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000015317.1|UniProtKB=W5NDY8 W5NDY8 PTHR12228:SF0 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000013387.1|UniProtKB=W5N798 W5N798 PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE oxidase#PC00175;oxidoreductase#PC00176 Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120 LEPOC|Ensembl=ENSLOCG00000011944.1|UniProtKB=W5N228 W5N228 PTHR19290:SF150 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED ATONAL BHLH TRANSCRIPTION FACTOR 1B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003852.1|UniProtKB=W5M894 W5M894 PTHR15337:SF10 ANTERIOR GRADIENT PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 12 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001160.1|UniProtKB=W5LYX3 W5LYX3 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC-CHELATE REDUCTASE 1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013779.1|UniProtKB=W5N8N6 W5N8N6 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008897.1|UniProtKB=W5MR24 W5MR24 UBQLN4 PTHR10677:SF21 UBIQUILIN UBIQUILIN-4 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010493.1|UniProtKB=W5MWV2 W5MWV2 PTHR31663:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING 3B LEPOC|Ensembl=ENSLOCG00000014087.1|UniProtKB=W5N9P9 W5N9P9 NINJ1 PTHR12316:SF19 NINJURIN-RELATED NINJURIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000669.1|UniProtKB=W5LXD2 W5LXD2 PTHR24394:SF0 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 40 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007928.1|UniProtKB=W5MML8 W5MML8 PTHR45753:SF3 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846 LEPOC|Ensembl=ENSLOCG00000008268.1|UniProtKB=W5MNT5 W5MNT5 PTHR23123:SF3 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2A histone modifying activity#GO:0140993;molecular adaptor activity#GO:0060090;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000011430.1|UniProtKB=W5N085 W5N085 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000012167.1|UniProtKB=W5N2V7 W5N2V7 PTHR11630:SF71 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;mitotic DNA replication initiation#GO:1902975;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002384.1|UniProtKB=W5M339 W5M339 PTHR15348:SF1 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016372.1|UniProtKB=W5NHV7 W5NHV7 PTHR23281:SF13 MERLIN/MOESIN/EZRIN/RADIXIN EZRIN cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 microvillus#GO:0005902;filopodium#GO:0030175;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;actin-based cell projection#GO:0098858;adherens junction#GO:0005912;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006075.1|UniProtKB=W5MG41 W5MG41 PTHR45620:SF21 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014159.1|UniProtKB=W5N9Y3 W5N9Y3 PTHR11671:SF1 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D ATPase complex#GO:1904949;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013879.1|UniProtKB=W5N908 W5N908 PTHR19965:SF82 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015976.1|UniProtKB=W5NGD5 W5NGD5 PTHR24115:SF978 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017382.1|UniProtKB=W5NLH8 W5NLH8 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008264.1|UniProtKB=W5MNT3 W5MNT3 PTHR10110:SF56 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 5 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004750.1|UniProtKB=W5MBD7 W5MBD7 PTHR19300:SF45 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 5 UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014708.1|UniProtKB=W5NBU6 W5NBU6 PTHR11304:SF17 EPHRIN EPHRIN-B1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Angiogenesis#P00005>Eph#P00239 LEPOC|Ensembl=ENSLOCG00000016177.1|UniProtKB=W5NH29 W5NH29 PTHR32078:SF1 NUCLEAR PROTEIN MDM1 NUCLEAR PROTEIN MDM1 LEPOC|Ensembl=ENSLOCG00000010704.1|UniProtKB=W5MXK1 W5MXK1 PTHR15503:SF39 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000001967.1|UniProtKB=W5M1L8 W5M1L8 PTHR42748:SF7 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA LIKE REDOX SENSOR 1-RELATED LEPOC|Ensembl=ENSLOCG00000004755.1|UniProtKB=W5MBE3 W5MBE3 PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 LEPOC|Ensembl=ENSLOCG00000015152.1|UniProtKB=W5NDD7 W5NDD7 PTHR15348:SF30 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009772.1|UniProtKB=W5MUA8 W5MUA8 PTHR14166:SF8 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 3 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of locomotion#GO:0040013;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000000762.1|UniProtKB=W5LXJ1 W5LXJ1 PTHR10030:SF45 ALPHA-L-FUCOSIDASE PLASMA ALPHA-L-FUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016916.1|UniProtKB=W5NJV3 W5NJV3 PTHR11575:SF24 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 LEPOC|Ensembl=ENSLOCG00000008971.1|UniProtKB=W5MRC2 W5MRC2 PTHR10574:SF292 NETRIN/LAMININ-RELATED NETRIN-3 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 LEPOC|Ensembl=ENSLOCG00000013614.1|UniProtKB=W5N823 W5N823 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000000054.1|UniProtKB=W5LVA7 W5LVA7 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010524.1|UniProtKB=W5MWY7 W5MWY7 PTHR23320:SF170 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE SPANNING 4-DOMAINS A12 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009973.1|UniProtKB=W5MUY6 W5MUY6 PTHR19957:SF104 SYNTAXIN SYNTAXIN-6 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 SNARE protein#PC00034;membrane traffic protein#PC00150 Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074 LEPOC|Ensembl=ENSLOCG00000011889.1|UniProtKB=W5N1W2 W5N1W2 PTHR23322:SF1 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005031.1|UniProtKB=W5MCE8 W5MCE8 CIRBP PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015757.1|UniProtKB=W5NFI9 W5NFI9 PTHR24083:SF49 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011763.1|UniProtKB=W5N1G7 W5N1G7 PTHR13793:SF93 PHD FINGER PROTEINS PROTEIN AF-10 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018313.1|UniProtKB=W5NP55 W5NP55 PTHR15718:SF7 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004179.1|UniProtKB=W5M9H7 W5M9H7 PTHR24416:SF535 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;cell communication#GO:0007154;chemical homeostasis#GO:0048878;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;carbohydrate homeostasis#GO:0033500;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;plasma membrane signaling receptor complex#GO:0098802;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;axon#GO:0030424;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>IR#P06802;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 LEPOC|Ensembl=ENSLOCG00000013350.1|UniProtKB=W5N741 W5N741 CXCL8 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A PLATELET BASIC PROTEIN cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004141.1|UniProtKB=W5M992 W5M992 PTHR15193:SF1 CD83 ANTIGEN CD83 ANTIGEN LEPOC|Ensembl=ENSLOCG00000014328.1|UniProtKB=W5NAJ1 W5NAJ1 PTHR10183:SF434 CALPAIN CALPAIN-3 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003519.1|UniProtKB=W5M714 W5M714 PTHR11849:SF160 ETS ETS TRANSLOCATION VARIANT 5 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000009875.1|UniProtKB=W5MUL0 W5MUL0 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA LEPOC|Ensembl=ENSLOCG00000014660.1|UniProtKB=W5NBQ4 W5NBQ4 PTHR22625:SF69 PLEXIN PLEXIN-B3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;regulation of GTPase activity#GO:0043087;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of nervous system development#GO:0051962;positive regulation of developmental process#GO:0051094;regulation of neuron projection development#GO:0010975;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of multicellular organismal process#GO:0051240 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013248.1|UniProtKB=W5N6R2 W5N6R2 PTHR15593:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 6 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Endothelin signaling pathway#P00019>PI3K#P00577;EGF receptor signaling pathway#P00018>PI3K#P00557 LEPOC|Ensembl=ENSLOCG00000001857.1|UniProtKB=W5M1B3 W5M1B3 PTHR22750:SF49 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000404.1|UniProtKB=W5LWD9 W5LWD9 PTHR43570:SF7 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017584.1|UniProtKB=W5NM30 W5NM30 RGS9BP PTHR21029:SF1 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 9-BINDING PROTEIN signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;cell communication#GO:0007154;nervous system process#GO:0050877;visual perception#GO:0007601;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to radiation#GO:0009314;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;response to abiotic stimulus#GO:0009628;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000014887.1|UniProtKB=W5NCH4 W5NCH4 PTHR22406:SF5 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN-LIKE regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;cytoplasmic microtubule organization#GO:0031122;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;microtubule nucleation#GO:0007020 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016312.1|UniProtKB=W5NHN2 W5NHN2 PTHR12587:SF6 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-2 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012414.1|UniProtKB=W5N3S3 W5N3S3 YIPF7 PTHR21236:SF5 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF7 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;Golgi organization#GO:0007030;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017688.1|UniProtKB=W5NMD4 W5NMD4 PTHR40472:SF8 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 2 LEPOC|Ensembl=ENSLOCG00000008173.1|UniProtKB=W5MNG2 W5MNG2 PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000009551.1|UniProtKB=W5MTG7 W5MTG7 PTHR12549:SF8 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3B histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;histone demethylase activity#GO:0032452;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;demethylase activity#GO:0032451;molecular adaptor activity#GO:0060090;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014688.1|UniProtKB=W5NBS6 W5NBS6 PTHR12659:SF3 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 8 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000005047.1|UniProtKB=W5MCK4 W5MCK4 NCKAP1L PTHR12093:SF9 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1-LIKE cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699;cell migration#GO:0016477;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011240.1|UniProtKB=W5MZL7 W5MZL7 PTHR16212:SF4 FOCADHESIN FAMILY MEMBER FOCADHESIN LEPOC|Ensembl=ENSLOCG00000015327.1|UniProtKB=W5NE00 W5NE00 PTHR10985:SF76 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of multicellular organismal process#GO:0051239;circadian rhythm#GO:0007623;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;circadian regulation of gene expression#GO:0032922;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008138.1|UniProtKB=W5MNB6 W5MNB6 PTHR43856:SF1 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000006067.1|UniProtKB=W5MG16 W5MG16 PTHR12645:SF0 ALR/ERV FAD-LINKED SULFHYDRYL OXIDASE ALR nucleotide binding#GO:0000166;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;disulfide oxidoreductase activity#GO:0015036;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009213.1|UniProtKB=W5MS78 W5MS78 PTHR11086:SF14 DEOXYCYTIDYLATE DEAMINASE-RELATED CYTIDINE AND DCMP DEAMINASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012330.1|UniProtKB=W5N3H6 W5N3H6 PTHR24355:SF15 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK6#P05939;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 LEPOC|Ensembl=ENSLOCG00000005372.1|UniProtKB=W5MDM1 W5MDM1 PTHR24348:SF18 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;macroautophagy#GO:0016236;regulation of catabolic process#GO:0009894;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component organization#GO:0051129;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;reticulophagy#GO:0061709;response to stress#GO:0006950;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;positive regulation of catabolic process#GO:0009896;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;autophagosome assembly#GO:0000045;positive regulation of autophagy#GO:0010508;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule modification#GO:0043412;developmental process#GO:0032502;positive regulation of cellular catabolic process#GO:0031331;protein modification process#GO:0036211;growth#GO:0040007;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;axon extension#GO:0048675;neuron differentiation#GO:0030182;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;regulation of cell development#GO:0060284;developmental growth#GO:0048589;regulation of autophagy#GO:0010506;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;cell growth#GO:0016049;organelle disassembly#GO:1903008;regulation of cellular component size#GO:0032535;organelle assembly#GO:0070925;cell development#GO:0048468;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of cell size#GO:0008361;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;response to starvation#GO:0042594;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;generation of neurons#GO:0048699 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000459.1|UniProtKB=W5LWJ4 W5LWJ4 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR ODORANT RECEPTOR-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012472.1|UniProtKB=W5N3Z6 W5N3Z6 BEND4 PTHR35082:SF1 BEN DOMAIN-CONTAINING PROTEIN 4 BEN DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005212.1|UniProtKB=W5MD15 W5MD15 PTHR24394:SF36 ZINC FINGER PROTEIN B-CELL LYMPHOMA 6 PROTEIN ISOFORM X1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015077.1|UniProtKB=W5ND48 W5ND48 PTHR21556:SF2 TRESLIN TRESLIN protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 DNA damage checkpoint signaling#GO:0000077;regulation of nitrogen compound metabolic process#GO:0051171;mitotic cell cycle checkpoint signaling#GO:0007093;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;organic cyclic compound metabolic process#GO:1901360;signal transduction in response to DNA damage#GO:0042770;mitotic DNA replication checkpoint signaling#GO:0033314;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;DNA replication checkpoint signaling#GO:0000076;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;DNA replication#GO:0006260;regulation of mitotic cell cycle#GO:0007346;mitotic DNA damage checkpoint signaling#GO:0044773;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001090.1|UniProtKB=W5LYM3 W5LYM3 PTHR11604:SF2 PROFILIN PROFILIN-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 negative regulation of protein polymerization#GO:0032272;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007772.1|UniProtKB=W5MM34 W5MM34 PTHR19850:SF31 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443 LEPOC|Ensembl=ENSLOCG00000009185.1|UniProtKB=W5MS42 W5MS42 PTHR10489:SF930 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;neutrophil migration#GO:1990266;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;granulocyte migration#GO:0097530;neutrophil chemotaxis#GO:0030593;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;myeloid leukocyte migration#GO:0097529;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;leukocyte chemotaxis#GO:0030595;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009090.1|UniProtKB=W5MRS3 W5MRS3 PTHR31914:SF2 PROTEIN FAM163A PROTEIN FAM163A LEPOC|Ensembl=ENSLOCG00000011553.1|UniProtKB=W5N0P2 W5N0P2 PTHR24103:SF590 E3 UBIQUITIN-PROTEIN LIGASE TRIM BUTYROPHILIN SUBFAMILY 3 MEMBER A1-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009942.1|UniProtKB=W5MUV0 W5MUV0 PTHR16487:SF0 PPP4R2-RELATED PROTEIN PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000003424.1|UniProtKB=W5M6T9 W5M6T9 PTHR11654:SF89 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 1 amide transmembrane transporter activity#GO:0042887;oligopeptide transmembrane transporter activity#GO:0035673;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;oligopeptide transport#GO:0006857;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;nitrogen compound transport#GO:0071705;dipeptide transport#GO:0042938;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;import into cell#GO:0098657 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004500.1|UniProtKB=W5MAI7 W5MAI7 PTHR13439:SF2 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane assembly#GO:0071709;regulation of biological quality#GO:0065008;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011623.1|UniProtKB=W5N0X8 W5N0X8 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010855.1|UniProtKB=W5MY46 W5MY46 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012081.1|UniProtKB=W5N2K4 W5N2K4 PTHR13355:SF11 GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000015594.1|UniProtKB=W5NEZ2 W5NEZ2 PTHR11036:SF16 SEMAPHORIN SEMAPHORIN-4C molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 bounding membrane of organelle#GO:0098588;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014744.1|UniProtKB=W5NBZ2 W5NBZ2 PTHR37948:SF1 ZGC:113208 BLL5189 PROTEIN LEPOC|Ensembl=ENSLOCG00000006824.1|UniProtKB=W5MIN5 W5MIN5 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 KERATINOCYTE-ASSOCIATED PROTEIN 2 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000000711.1|UniProtKB=W5LXD1 W5LXD1 PTHR23266:SF390 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003348.1|UniProtKB=W5M6E5 W5M6E5 PTHR22768:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 cellular aromatic compound metabolic process#GO:0006725;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle#GO:0000278;mitotic DNA replication initiation#GO:1902975;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic DNA replication#GO:1902969;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cell cycle DNA replication#GO:0044786 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000001718.1|UniProtKB=W5M0T3 W5M0T3 PTHR11532:SF43 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE X1-RELATED metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009332.1|UniProtKB=W5MSM8 W5MSM8 PTHR14628:SF1 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000014721.1|UniProtKB=W5NBW6 W5NBW6 PTHR24240:SF19 OPSIN BLUE SENSITIVE CONE OPSIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013112.1|UniProtKB=W5N693 W5N693 PTHR24161:SF110 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED USHER SYNDROME TYPE-1G PROTEIN protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003378.1|UniProtKB=W5M6J2 W5M6J2 CPQ PTHR12053:SF3 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012679.1|UniProtKB=W5N4N8 W5N4N8 GIMD1 PTHR10903:SF103 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER GIMD1 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010260.1|UniProtKB=W5MW03 W5MW03 PTHR22647:SF3 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000369.1|UniProtKB=W5LW94 W5LW94 PTHR47027:SF29 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008275.1|UniProtKB=W5MNU5 W5MNU5 PTHR45949:SF3 SORTING NEXIN-4 SORTING NEXIN-7 endosomal transport#GO:0016197;microautophagy#GO:0016237;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;autophagy of mitochondrion#GO:0000422;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 cytoplasm#GO:0005737;endosome#GO:0005768;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000085.1|UniProtKB=W5LVE3 W5LVE3 PTHR12346:SF1 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 LEPOC|Ensembl=ENSLOCG00000012523.1|UniProtKB=W5N462 W5N462 PTHR46778:SF1 CYCLIN-DEPENDENT KINASE INHIBITOR 1-RELATED CYCLIN-DEPENDENT KINASE INHIBITOR 1 protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;enzyme regulator activity#GO:0030234 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;DNA damage response#GO:0006974;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;negative regulation of phosphorus metabolic process#GO:0010563;regulation of cell cycle phase transition#GO:1901987;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase inhibitor#PC00139 p53 pathway#P00059>P21#P04631;p53 pathway feedback loops 2#P04398>P21#G04712;p53 pathway feedback loops 2#P04398>p21#P04667;Interleukin signaling pathway#P00036>p21CIP1#P00993;p53 pathway#P00059>p21#G01580 LEPOC|Ensembl=ENSLOCG00000013039.1|UniProtKB=W5N602 W5N602 PTHR33559:SF1 PROTEASOME ASSEMBLY CHAPERONE 4 PROTEASOME ASSEMBLY CHAPERONE 4 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017678.1|UniProtKB=W5NMC4 W5NMC4 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017694.1|UniProtKB=W5NME0 W5NME0 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012506.1|UniProtKB=W5N437 W5N437 PTHR15240:SF3 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;plasma membrane raft#GO:0044853;caveola#GO:0005901;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 General transcription by RNA polymerase I#P00022>PTRF#P00656 LEPOC|Ensembl=ENSLOCG00000015387.1|UniProtKB=W5NE74 W5NE74 PTHR10176:SF1 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, LIVER UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;glucan biosynthetic process#GO:0009250;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 LEPOC|Ensembl=ENSLOCG00000016314.1|UniProtKB=W5NHM9 W5NHM9 PTHR11647:SF58 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125;Axon guidance mediated by semaphorins#P00007>CRAM#P00330 LEPOC|Ensembl=ENSLOCG00000008541.1|UniProtKB=W5MPU4 W5MPU4 PTHR10336:SF79 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;positive regulation of cell motility#GO:2000147;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;regulation of multicellular organismal process#GO:0051239;transmembrane transport#GO:0055085;regulation of cell motility#GO:2000145;calcium ion transmembrane transport#GO:0070588;positive regulation of locomotion#GO:0040017;release of sequestered calcium ion into cytosol#GO:0051209;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000012987.1|UniProtKB=W5N5T3 W5N5T3 PTHR46262:SF3 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000000675.1|UniProtKB=W5LX90 W5LX90 PTHR10989:SF11 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-INDUCED GENE 1 PROTEIN cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000001774.1|UniProtKB=W5M104 W5M104 PTHR22765:SF34 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF13 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010410.1|UniProtKB=W5MWK3 W5MWK3 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 LEPOC|Ensembl=ENSLOCG00000001254.1|UniProtKB=W5LZ72 W5LZ72 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015231.1|UniProtKB=W5NDN3 W5NDN3 PTHR24067:SF243 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 A ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;protein-DNA complex#GO:0032993;chromosome#GO:0005694;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000006217.1|UniProtKB=W5MGJ7 W5MGJ7 SHISAL2A PTHR31395:SF3 SHISA PROTEIN SHISA-LIKE-2A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004331.1|UniProtKB=W5M9W1 W5M9W1 PTHR24338:SF9 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015933.1|UniProtKB=W5NG57 W5NG57 PTHR14437:SF2 TRANSMEMBRANE PROTEIN 168 TRANSMEMBRANE PROTEIN 168 LEPOC|Ensembl=ENSLOCG00000009445.1|UniProtKB=W5MT19 W5MT19 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000014299.1|UniProtKB=W5NAE7 W5NAE7 PTHR10117:SF76 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 5 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000018062.1|UniProtKB=W5NNF4 W5NNF4 PTHR10003:SF77 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN] cation binding#GO:0043169;antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;response to reactive oxygen species#GO:0000302;cellular response to stress#GO:0033554;metabolic process#GO:0008152 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016531.1|UniProtKB=W5NIF8 W5NIF8 PTHR16515:SF68 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017856.1|UniProtKB=W5NMV0 W5NMV0 PTHR22750:SF10 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009280.1|UniProtKB=W5MSG0 W5MSG0 PTHR10613:SF0 LEUKOCYTE SURFACE ANTIGEN CD47 LEUKOCYTE SURFACE ANTIGEN CD47 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015624.1|UniProtKB=W5NF34 W5NF34 PTHR13018:SF38 PROBABLE MEMBRANE PROTEIN DUF221-RELATED CSC1-LIKE PROTEIN 2 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002842.1|UniProtKB=W5M4N3 W5M4N3 PTHR48051:SF13 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 30 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002517.1|UniProtKB=W5M3K3 W5M3K3 PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016278.1|UniProtKB=W5NHH1 W5NHH1 PTHR24215:SF3 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 2 structural constituent of muscle#GO:0008307;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000018279.1|UniProtKB=W5NP21 W5NP21 PTHR20855:SF96 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER VII, A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;response to steroid hormone#GO:0048545 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013038.1|UniProtKB=W5N5Z9 W5N5Z9 PTHR47501:SF6 TRANSPOSASE-RELATED SUBFAMILY NOT NAMED viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000016542.1|UniProtKB=W5NIH9 W5NIH9 GRIK2 PTHR18966:SF38 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;sodium channel activity#GO:0005272;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796;Ionotropic glutamate receptor pathway#P00037>KA2#P01003 LEPOC|Ensembl=ENSLOCG00000007226.1|UniProtKB=W5MK31 W5MK31 PTHR16516:SF7 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;multicellular organism development#GO:0007275;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;oligodendrocyte differentiation#GO:0048709;regulation of RNA metabolic process#GO:0051252;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013354.1|UniProtKB=W5N787 W5N787 PTHR10972:SF146 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 envelope#GO:0031975;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015665.1|UniProtKB=W5NF74 W5NF74 PTHR10740:SF1 TRANSFORMING GROWTH FACTOR ALPHA PROTRANSFORMING GROWTH FACTOR ALPHA molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of mitotic nuclear division#GO:0007088;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of organelle organization#GO:0010638;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of mitotic cell cycle#GO:0007346;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000003343.1|UniProtKB=W5M6I7 W5M6I7 PTHR23007:SF5 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;aminoacyltransferase activity#GO:0016755;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;SH3 domain binding#GO:0017124;transferase activity#GO:0016740;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of protein kinase activity#GO:0006469;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of kinase activity#GO:0043549;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of ERBB signaling pathway#GO:1901184;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 ligase#PC00142;metabolite interconversion enzyme#PC00262 EGF receptor signaling pathway#P00018>c-Cbl#P00544 LEPOC|Ensembl=ENSLOCG00000010457.1|UniProtKB=W5MWQ8 W5MWQ8 PTHR14649:SF1 ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C LEPOC|Ensembl=ENSLOCG00000012726.1|UniProtKB=W5N4V1 W5N4V1 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 LEPOC|Ensembl=ENSLOCG00000003911.1|UniProtKB=W5M8G5 W5M8G5 PTHR23253:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001511.1|UniProtKB=W5M016 W5M016 PTHR45632:SF15 LD33804P BTB DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013928.1|UniProtKB=W5N966 W5N966 PTHR12845:SF7 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 15 positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008800.1|UniProtKB=W5MQQ3 W5MQQ3 PTHR16557:SF2 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;catalytic activity, acting on a nucleic acid#GO:0140640;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;cation binding#GO:0043169;catalytic activity, acting on RNA#GO:0140098;demethylase activity#GO:0032451;iron ion binding#GO:0005506;dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;DNA modification#GO:0006304;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA demethylation#GO:0080111;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007205.1|UniProtKB=W5MK10 W5MK10 PTHR23001:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;translation regulator activity, nucleic acid binding#GO:0090079;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation factor activity, RNA binding#GO:0008135 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000018055.1|UniProtKB=W5NNE7 W5NNE7 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000016045.1|UniProtKB=W5NGK5 W5NGK5 PTHR22760:SF1 GLYCOSYLTRANSFERASE DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001452.1|UniProtKB=W5LZU9 W5LZU9 PTHR15892:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013402.1|UniProtKB=W5N7B7 W5N7B7 PTHR10288:SF279 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 4 ISOFORM X1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311;negative regulation of cellular biosynthetic process#GO:0031327 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014202.1|UniProtKB=W5NA34 W5NA34 PTHR47410:SF4 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;activation of immune response#GO:0002253;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;canonical NF-kappaB signal transduction#GO:0007249;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;positive regulation of macromolecule metabolic process#GO:0010604;defense response to symbiont#GO:0140546;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;signal transduction#GO:0007165;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cytokine production#GO:0001817;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007312.1|UniProtKB=W5MKF2 W5MKF2 PTHR11830:SF15 40S RIBOSOMAL PROTEIN S3A UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;protein K63-linked deubiquitination#GO:0070536;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of extrinsic apoptotic signaling pathway#GO:2001236;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of DNA-binding transcription factor activity#GO:0043433;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003716.1|UniProtKB=W5M7R5 W5M7R5 PTHR11477:SF50 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 3 ISOFORM X1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016524.1|UniProtKB=W5NIF3 W5NIF3 NCOA7 PTHR23354:SF68 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED NUCLEAR RECEPTOR COACTIVATOR 7 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;response to oxidative stress#GO:0006979;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010463.1|UniProtKB=W5MWR3 W5MWR3 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013397.1|UniProtKB=W5N7A2 W5N7A2 PTHR23268:SF124 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017252.1|UniProtKB=W5NL31 W5NL31 PTHR44889:SF1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013597.1|UniProtKB=W5N808 W5N808 PTHR44229:SF2 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006251.1|UniProtKB=W5MGP1 W5MGP1 PTHR19957:SF36 SYNTAXIN SYNTAXIN-2 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000008962.1|UniProtKB=W5MRA9 W5MRA9 PTHR15075:SF7 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002360.1|UniProtKB=W5M309 W5M309 PTHR10237:SF1 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014893.1|UniProtKB=W5NCI1 W5NCI1 PTHR46005:SF1 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 35 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of anatomical structure size#GO:0090066;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;regulation of cellular component size#GO:0032535;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of axonogenesis#GO:0050770;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003892.1|UniProtKB=W5M8E5 W5M8E5 PTHR10292:SF7 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;cell cycle#GO:0007049;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;microtubule cytoskeleton#GO:0015630;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;cytoskeleton#GO:0005856;spindle#GO:0005819 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 LEPOC|Ensembl=ENSLOCG00000013079.1|UniProtKB=W5N650 W5N650 PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 LEPOC|Ensembl=ENSLOCG00000004673.1|UniProtKB=W5MB34 W5MB34 PTHR10129:SF10 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFB sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000010487.1|UniProtKB=W5MWV1 W5MWV1 PTHR45971:SF2 PHOX (PX) DOMAIN-CONTAINING PROTEIN PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 vesicle fusion#GO:0006906;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagosome maturation#GO:0097352;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003022.1|UniProtKB=W5M599 W5M599 PTHR11818:SF11 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B2 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005080.1|UniProtKB=W5MCK8 W5MCK8 PTHR24390:SF227 ZINC FINGER PROTEIN KRUEPPEL HOMOLOG 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007346.1|UniProtKB=W5MKJ3 W5MKJ3 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated channel activity#GO:0022832;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000018101.1|UniProtKB=W5NNJ3 W5NNJ3 PTHR12137:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 12 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017050.1|UniProtKB=W5NKB1 W5NKB1 PTHR42757:SF30 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007023.1|UniProtKB=W5MJE3 W5MJE3 PTHR46059:SF2 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008253.1|UniProtKB=W5MNR9 W5MNR9 PTHR43073:SF2 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] dehydrogenase#PC00092;oxidoreductase#PC00176 Pyrimidine Metabolism#P02771>Dihydrouracil Dehydrogenase#P03128 LEPOC|Ensembl=ENSLOCG00000005464.1|UniProtKB=W5MDX9 W5MDX9 PTHR13318:SF179 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 15 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006047.1|UniProtKB=W5MG04 W5MG04 PTHR24356:SF230 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013659.1|UniProtKB=W5N881 W5N881 PTHR22883:SF270 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC15 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000538.1|UniProtKB=W5LWU2 W5LWU2 RPL7A PTHR23105:SF1 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013455.1|UniProtKB=W5N7H8 W5N7H8 PTHR45874:SF6 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-B10A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017156.1|UniProtKB=W5NKP4 W5NKP4 PTHR23359:SF148 NUCLEOTIDE KINASE ADENYLATE KINASE 9 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleoside diphosphate kinase activity#GO:0004550;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000011393.1|UniProtKB=W5N046 W5N046 PTHR45752:SF153 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003579.1|UniProtKB=W5M782 W5M782 PTHR25466:SF2 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 LEPOC|Ensembl=ENSLOCG00000000297.1|UniProtKB=W5LW16 W5LW16 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015570.1|UniProtKB=W5NEW1 W5NEW1 PTHR24248:SF145 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR D4 RELATED SEQUENCE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;regulation of metal ion transport#GO:0010959;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;negative regulation of lyase activity#GO:0051350;negative regulation of cell communication#GO:0010648;regulation of monoatomic ion transmembrane transport#GO:0034765;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;response to nitrogen compound#GO:1901698;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;negative regulation of monoatomic ion transport#GO:0043271;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;negative regulation of cyclase activity#GO:0031280;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of adenylate cyclase activity#GO:0007194;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004726.1|UniProtKB=W5MBA7 W5MBA7 PTHR14732:SF0 RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012423.1|UniProtKB=W5N3T9 W5N3T9 PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Oxidative stress response#P00046>Max#P01133 LEPOC|Ensembl=ENSLOCG00000016681.1|UniProtKB=W5NIZ9 W5NIZ9 PTHR45890:SF1 AARF DOMAIN CONTAINING KINASE 2 (PREDICTED) AARF DOMAIN CONTAINING KINASE 2 LEPOC|Ensembl=ENSLOCG00000012489.1|UniProtKB=W5N414 W5N414 SLC39A11 PTHR11040:SF211 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005597.1|UniProtKB=W5MEE9 W5MEE9 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;endoribonuclease complex#GO:1902555;ribonuclease MRP complex#GO:0000172;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012859.1|UniProtKB=W5N5C2 W5N5C2 PTHR14440:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;rRNA transcription#GO:0009303;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;transcription elongation by RNA polymerase I#GO:0006362;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000002923.1|UniProtKB=W5M4X6 W5M4X6 LYPD1 PTHR10036:SF7 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 1 signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 LEPOC|Ensembl=ENSLOCG00000011563.1|UniProtKB=W5N0P9 W5N0P9 PAIP2 PTHR13154:SF2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 translation regulator activity#GO:0045182 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002706.1|UniProtKB=W5M488 W5M488 PTHR10082:SF26 INTEGRIN BETA SUBUNIT INTEGRIN BETA-5 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;response to growth factor#GO:0070848;contractile actin filament bundle assembly#GO:0030038;cell adhesion mediated by integrin#GO:0033627;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to endogenous stimulus#GO:0009719;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;integrin-mediated signaling pathway#GO:0007229;cytoskeleton organization#GO:0007010;signaling#GO:0023052;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;stress fiber assembly#GO:0043149;actin filament bundle assembly#GO:0051017;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;actomyosin structure organization#GO:0031032;cell motility#GO:0048870;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cell-matrix adhesion#GO:0007160;organelle organization#GO:0006996;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 membrane protein complex#GO:0098796;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000005940.1|UniProtKB=W5MFL4 W5MFL4 KCNV1 PTHR11537:SF38 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000005858.1|UniProtKB=W5MFB4 W5MFB4 PTHR13847:SF187 SARCOSINE DEHYDROGENASE-RELATED DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011967.1|UniProtKB=W5N254 W5N254 PTHR22446:SF3 M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000012508.1|UniProtKB=W5N448 W5N448 PTHR10516:SF26 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016056.1|UniProtKB=W5NGM2 W5NGM2 PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014196.1|UniProtKB=W5NA28 W5NA28 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 LEPOC|Ensembl=ENSLOCG00000016307.1|UniProtKB=W5NHM0 W5NHM0 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013262.1|UniProtKB=W5N6S7 W5N6S7 LURAP1L PTHR33767:SF1 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1-LIKE regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000013617.1|UniProtKB=W5N835 W5N835 PTHR10887:SF365 DNA2/NAM7 HELICASE FAMILY HELICASE WITH ZINC FINGER DOMAIN-RELATED negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000001558.1|UniProtKB=W5M076 W5M076 PTHR11633:SF3 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT A growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 PDGF signaling pathway#P00047>PDGF#P01170;Angiogenesis#P00005>PDGF#P00224 LEPOC|Ensembl=ENSLOCG00000000709.1|UniProtKB=W5LXD0 W5LXD0 PTHR46664:SF1 ATM INTERACTOR ATM INTERACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012644.1|UniProtKB=W5N4L5 W5N4L5 PTHR22957:SF168 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015762.1|UniProtKB=W5NFJ5 W5NFJ5 PTHR46949:SF3 LEUCINE REPEAT ADAPTER PROTEIN 25 PROTEIN FAM89A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003880.1|UniProtKB=W5M8B6 W5M8B6 LHX3 PTHR24208:SF91 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017385.1|UniProtKB=W5NLI1 W5NLI1 SPTSSB PTHR28612:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012461.1|UniProtKB=W5N3Y4 W5N3Y4 PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 LEPOC|Ensembl=ENSLOCG00000009018.1|UniProtKB=W5MRK1 W5MRK1 PTHR23511:SF11 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2A synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000012013.1|UniProtKB=W5N2B9 W5N2B9 PTHR24270:SF2 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000013378.1|UniProtKB=W5N779 W5N779 PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 telomere maintenance via telomere lengthening#GO:0010833;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;telomere capping#GO:0016233;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nuclear telomere cap complex#GO:0000783;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear protein-containing complex#GO:0140513 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002833.1|UniProtKB=W5M4P4 W5M4P4 PTHR19957:SF97 SYNTAXIN SYNTAXIN-4 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;export from cell#GO:0140352;secretion by cell#GO:0032940;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000011012.1|UniProtKB=W5MYQ6 W5MYQ6 PTHR24327:SF31 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004896.1|UniProtKB=W5MBY0 W5MBY0 PTHR24020:SF13 COLLAGEN ALPHA COLLAGEN ALPHA-3(VI) CHAIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000009532.1|UniProtKB=W5MTE1 W5MTE1 PTHR22750:SF3 G-PROTEIN COUPLED RECEPTOR ADRENOCORTICOTROPIC HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007128.1|UniProtKB=W5MJS0 W5MJS0 PTHR23113:SF197 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1B nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017116.1|UniProtKB=W5NKJ4 W5NKJ4 PTHR14015:SF0 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR-LIKE PROTEIN 1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016224.1|UniProtKB=W5NHA0 W5NHA0 PTHR46198:SF2 PROTEIN-TYROSINE-PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cell junction#GO:0030054;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015789.1|UniProtKB=W5NFM9 W5NFM9 PTHR11537:SF265 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic membrane#GO:0045211;neuronal cell body#GO:0043025;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000003221.1|UniProtKB=W5M605 W5M605 PTHR11963:SF23 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012524.1|UniProtKB=W5N464 W5N464 PTHR10740:SF4 TRANSFORMING GROWTH FACTOR ALPHA PROHEPARIN-BINDING EGF-LIKE GROWTH FACTOR molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of mitotic nuclear division#GO:0007088;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of organelle organization#GO:0010638;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of mitotic cell cycle#GO:0007346;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 CCKR signaling map#P06959>HBEGF#G07261;EGF receptor signaling pathway#P00018>EGF#P00549;CCKR signaling map#P06959>HBEGF#G06968;CCKR signaling map#P06959>Pro HBEGF#P07182;CCKR signaling map#P06959>HBEGF#P07025 LEPOC|Ensembl=ENSLOCG00000018227.1|UniProtKB=W5NNW9 W5NNW9 PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000016464.1|UniProtKB=W5NI79 W5NI79 RERG PTHR24070:SF373 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 PDGF signaling pathway#P00047>Ras#P01154 LEPOC|Ensembl=ENSLOCG00000000450.1|UniProtKB=W5LWI6 W5LWI6 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000015344.1|UniProtKB=W5NE25 W5NE25 PTHR11825:SF70 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, CYTOSOLIC transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;leucine biosynthetic process#GO:0009098;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994 LEPOC|Ensembl=ENSLOCG00000013203.1|UniProtKB=W5N6N9 W5N6N9 PTHR45615:SF24 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-10 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cell division#GO:0051301;regulation of anatomical structure morphogenesis#GO:0022603;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;regulation of cell shape#GO:0008360;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000010774.1|UniProtKB=W5MXU3 W5MXU3 PTHR13948:SF21 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003931.1|UniProtKB=W5M8I6 W5M8I6 PTHR11848:SF145 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 10 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000006040.1|UniProtKB=W5MFY3 W5MFY3 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 21 binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;amide binding#GO:0033218 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014828.1|UniProtKB=W5NC99 W5NC99 PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 5 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003002.1|UniProtKB=W5M579 W5M579 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006276.1|UniProtKB=W5MGS1 W5MGS1 PTHR46222:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010515.1|UniProtKB=W5MWY3 W5MWY3 PTHR23113:SF357 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002219.1|UniProtKB=W5M2H6 W5M2H6 PTHR23349:SF4 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000011029.1|UniProtKB=W5MYS7 W5MYS7 PTHR46458:SF19 BLR2807 PROTEIN NEUROGLOBIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005150.1|UniProtKB=W5MCU2 W5MCU2 PTHR21433:SF2 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120B cellular developmental process#GO:0048869;cell differentiation#GO:0030154;fat cell differentiation#GO:0045444;cellular process#GO:0009987;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005416.1|UniProtKB=W5MDS5 W5MDS5 PTHR16040:SF10 AUSTRALIN, ISOFORM A-RELATED BOREALIN-2 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;spindle midzone#GO:0051233;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000654.1|UniProtKB=W5LX67 W5LX67 PTHR21344:SF1 RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 LEPOC|Ensembl=ENSLOCG00000012435.1|UniProtKB=W5N3X0 W5N3X0 PTHR24092:SF221 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IA ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011616.1|UniProtKB=W5N0W6 W5N0W6 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011669.1|UniProtKB=W5N130 W5N130 PTHR16039:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;spindle assembly#GO:0051225;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000003066.1|UniProtKB=W5M5H1 W5M5H1 PTHR43157:SF64 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 14 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016879.1|UniProtKB=W5NJQ7 W5NJQ7 PTHR12874:SF29 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013554.1|UniProtKB=W5N7W2 W5N7W2 PTHR11254:SF300 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF2 SMAD binding#GO:0046332;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of BMP signaling pathway#GO:0030514;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of cellular response to growth factor stimulus#GO:0090287;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;TGF-beta signaling pathway#P00052>Smurfs#P01279 LEPOC|Ensembl=ENSLOCG00000006260.1|UniProtKB=W5MGQ4 W5MGQ4 PTHR15732:SF4 PROTEIN MOONRAKER PROTEIN MOONRAKER localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007091.1|UniProtKB=W5MJP2 W5MJP2 PTHR12771:SF23 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 1 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 LEPOC|Ensembl=ENSLOCG00000006931.1|UniProtKB=W5MJ23 W5MJ23 MOCS2 PTHR33359:SF1 MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000007265.1|UniProtKB=W5MK83 W5MK83 ARHGAP6 PTHR12635:SF14 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 6 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001762.1|UniProtKB=W5M0Y2 W5M0Y2 PTHR43294:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013637.1|UniProtKB=W5N861 W5N861 PTHR11902:SF5 ENOLASE BETA-ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000018347.1|UniProtKB=W5NP89 W5NP89 PTHR46948:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P38 RIBONUCLEASE P PROTEIN SUBUNIT P38 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006563.1|UniProtKB=W5MHS0 W5MHS0 PTHR15904:SF19 FAM13 PROTEIN FAM13C LEPOC|Ensembl=ENSLOCG00000007851.1|UniProtKB=W5MMC6 W5MMC6 PTHR18934:SF88 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX32-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000000012.1|UniProtKB=W5LV61 W5LV61 PTHR10644:SF3 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013021.1|UniProtKB=W5N5Y2 W5N5Y2 PTHR24173:SF33 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005622.1|UniProtKB=W5MEH8 W5MEH8 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009874.1|UniProtKB=W5MUK9 W5MUK9 PTHR21292:SF4 EXOCYST COMPLEX COMPONENT SEC6-RELATED TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008718.1|UniProtKB=W5MQF5 W5MQF5 PTHR13128:SF12 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013533.1|UniProtKB=W5N7S9 W5N7S9 PTHR11909:SF451 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;plasma membrane bounded cell projection organization#GO:0120036;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell projection assembly#GO:0030031;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000564.1|UniProtKB=W5LWW4 W5LWW4 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014060.1|UniProtKB=W5N9L6 W5N9L6 PTHR15159:SF2 NEUROSECRETORY PROTEIN VGF NEUROSECRETORY PROTEIN VGF intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004074.1|UniProtKB=W5M908 W5M908 PTHR12114:SF6 PARVIN ALPHA-PARVIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;substrate adhesion-dependent cell spreading#GO:0034446;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085 Integrin signalling pathway#P00034>Parvin#P00945 LEPOC|Ensembl=ENSLOCG00000011972.1|UniProtKB=W5N264 W5N264 PTHR48207:SF3 SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866 LEPOC|Ensembl=ENSLOCG00000018134.1|UniProtKB=W5NNM6 W5NNM6 PTHR10489:SF733 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 4 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002732.1|UniProtKB=W5M4A8 W5M4A8 PTHR24037:SF3 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 PROTEIN HEG HOMOLOG 1 LEPOC|Ensembl=ENSLOCG00000002767.1|UniProtKB=W5M4F8 W5M4F8 PTHR19282:SF44 TETRASPANIN CD82 ANTIGEN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 p53 pathway#P00059>KAI#G04704 LEPOC|Ensembl=ENSLOCG00000017788.1|UniProtKB=W5NMN3 W5NMN3 KCNE2 PTHR15282:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;molecular function regulator activity#GO:0098772;binding#GO:0005488;delayed rectifier potassium channel activity#GO:0005251;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;protein binding#GO:0005515;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 blood circulation#GO:0008015;negative regulation of biological process#GO:0048519;actin filament-based movement#GO:0030048;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;regulation of system process#GO:0044057;inorganic ion transmembrane transport#GO:0098660;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;actin filament-based process#GO:0030029;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;potassium ion transport#GO:0006813;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of heart contraction#GO:0008016;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cardiac muscle contraction#GO:0060048;negative regulation of transport#GO:0051051;cellular process#GO:0009987;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;localization#GO:0051179;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;muscle system process#GO:0003012;export from cell#GO:0140352;heart process#GO:0003015;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000009142.1|UniProtKB=W5MRY6 W5MRY6 PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN LEPOC|Ensembl=ENSLOCG00000012985.1|UniProtKB=W5N5T1 W5N5T1 PTHR16155:SF20 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008156.1|UniProtKB=W5MNE1 W5MNE1 PTHR26451:SF980 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GENE 7582-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006020.1|UniProtKB=W5MFW1 W5MFW1 PTHR47195:SF1 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000007901.1|UniProtKB=W5MMI6 W5MMI6 PTHR46343:SF1 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX lysosome organization#GO:0007040;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;establishment of localization#GO:0051234;phagolysosome assembly#GO:0001845;organelle organization#GO:0006996;vesicle organization#GO:0016050;lytic vacuole organization#GO:0080171;import into cell#GO:0098657 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000015167.1|UniProtKB=W5NDF8 W5NDF8 PTHR11532:SF48 PROTEASE M14 CARBOXYPEPTIDASE ADIPOCYTE ENHANCER-BINDING PROTEIN 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;peptidase activity#GO:0008233;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;protein processing#GO:0016485;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;proteolysis#GO:0006508;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003381.1|UniProtKB=W5M6J9 W5M6J9 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000004605.1|UniProtKB=W5MAX6 W5MAX6 PTHR18945:SF52 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422;Gonadotropin-releasing hormone receptor pathway#P06664>5-HT3AR#P06833 LEPOC|Ensembl=ENSLOCG00000008110.1|UniProtKB=W5MN92 W5MN92 PTHR23037:SF28 CYTOKINE RECEPTOR ERYTHROPOIETIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014635.1|UniProtKB=W5NBK5 W5NBK5 PTHR15002:SF0 RIBOSOMAL BIOGENESIS PROTEIN LAS1L RIBOSOMAL BIOGENESIS PROTEIN LAS1L cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000007381.1|UniProtKB=W5MKP2 W5MKP2 PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017958.1|UniProtKB=W5NN52 W5NN52 PTHR19297:SF81 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015979.1|UniProtKB=W5NGB6 W5NGB6 PTHR12202:SF0 ESF1 HOMOLOG ESF1 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000016825.1|UniProtKB=W5NJI6 W5NJI6 PTHR11783:SF107 SULFOTRANSFERASE SULT SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011865.1|UniProtKB=W5N1T0 W5N1T0 PTHR10656:SF8 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017776.1|UniProtKB=W5NMM1 W5NMM1 C21orf62 PTHR35658:SF1 RCG58666, ISOFORM CRA_A CHROMOSOME 21 OPEN READING FRAME 62 LEPOC|Ensembl=ENSLOCG00000011333.1|UniProtKB=W5MZW7 W5MZW7 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014022.1|UniProtKB=W5N9I0 W5N9I0 PTHR24173:SF23 ANKYRIN REPEAT CONTAINING UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;negative regulation of biological process#GO:0048519;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;negative regulation of signaling#GO:0023057;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013577.1|UniProtKB=W5N7Y1 W5N7Y1 PTHR46232:SF1 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;nuclear receptor binding#GO:0016922;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000017789.1|UniProtKB=W5NMN4 W5NMN4 PTHR11984:SF13 CONNEXIN GAP JUNCTION ALPHA-5 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 heart development#GO:0007507;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;regulation of heart contraction#GO:0008016;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;regulation of system process#GO:0044057;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000006814.1|UniProtKB=W5MIM3 W5MIM3 PTHR46708:SF10 TENASCIN RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA-LIKE extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000016874.1|UniProtKB=W5NJQ4 W5NJQ4 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 LEPOC|Ensembl=ENSLOCG00000010749.1|UniProtKB=W5MXR7 W5MXR7 LTBP2 PTHR24034:SF49 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 2 extracellular matrix binding#GO:0050840;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;supramolecular fiber organization#GO:0097435 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000010041.1|UniProtKB=W5MV70 W5MV70 PTHR42760:SF115 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007174.1|UniProtKB=W5MJX2 W5MJX2 PTHR11675:SF18 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 12 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006451.1|UniProtKB=W5MHE0 W5MHE0 PTHR22781:SF12 DELTA ADAPTIN-RELATED AP-3 COMPLEX SUBUNIT DELTA-1 cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015769.1|UniProtKB=W5NFK4 W5NFK4 PTHR46944:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014731.1|UniProtKB=W5NBX9 W5NBX9 PTHR21292:SF17 EXOCYST COMPLEX COMPONENT SEC6-RELATED TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 2 ISOFORM X1 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007518.1|UniProtKB=W5ML72 W5ML72 PTHR14095:SF3 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005527.1|UniProtKB=W5ME61 W5ME61 PTHR46160:SF9 ALPHA-TECTORIN-RELATED PROTEIN PRY2-RELATED LEPOC|Ensembl=ENSLOCG00000002949.1|UniProtKB=W5M517 W5M517 PTHR16208:SF4 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTABULIN cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;axo-dendritic transport#GO:0008088;synapse organization#GO:0050808;system development#GO:0048731;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000011015.1|UniProtKB=W5MYR3 W5MYR3 PTHR24408:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 672-RELATED sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010131.1|UniProtKB=W5MVI7 W5MVI7 PTHR20968:SF4 ILGF DOMAIN-CONTAINING PROTEIN RELAXIN 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 LEPOC|Ensembl=ENSLOCG00000008111.1|UniProtKB=W5MN93 W5MN93 PTHR24230:SF61 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001337.1|UniProtKB=W5LZG9 W5LZG9 PTHR45614:SF30 MYB PROTEIN-RELATED MYB-RELATED PROTEIN B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;mitotic cell cycle#GO:0000278;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003090.1|UniProtKB=W5M5I0 W5M5I0 NTHL1 PTHR43286:SF1 ENDONUCLEASE III-LIKE PROTEIN 1 ENDONUCLEASE III-LIKE PROTEIN 1 catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000015655.1|UniProtKB=W5NF63 W5NF63 PTHR11070:SF30 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER F-BOX DNA HELICASE 1 ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002006.1|UniProtKB=W5M1R5 W5M1R5 PTHR24070:SF199 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Ral#P04550 LEPOC|Ensembl=ENSLOCG00000005463.1|UniProtKB=W5MDY8 W5MDY8 PTHR23239:SF349 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;keratin filament#GO:0045095;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016168.1|UniProtKB=W5NH13 W5NH13 PTHR23115:SF302 TRANSLATION FACTOR TR-TYPE G DOMAIN-CONTAINING PROTEIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004139.1|UniProtKB=W5M994 W5M994 PTHR16515:SF19 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 14 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009188.1|UniProtKB=W5MS49 W5MS49 C1orf35 PTHR14580:SF0 MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000430.1|UniProtKB=W5LWG2 W5LWG2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016468.1|UniProtKB=W5NI83 W5NI83 PTHR22961:SF15 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010679.1|UniProtKB=W5MXG9 W5MXG9 PTHR10281:SF24 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015654.1|UniProtKB=W5NF58 W5NF58 PTHR24198:SF185 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN-3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004249.1|UniProtKB=W5M9L9 W5M9L9 AK6 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009768.1|UniProtKB=W5MU79 W5MU79 PTHR43853:SF8 3-KETOACYL-COA THIOLASE, PEROXISOMAL 3-KETOACYL-COA THIOLASE, PEROXISOMAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;organic cyclic compound metabolic process#GO:1901360;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;response to chemical#GO:0042221;organic cyclic compound catabolic process#GO:1901361;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000013817.1|UniProtKB=W5N8S9 W5N8S9 PTHR31395:SF14 SHISA PROTEIN SHISA-5 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008724.1|UniProtKB=W5MQF9 W5MQF9 PTHR11890:SF6 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR 1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007196.1|UniProtKB=W5MK26 W5MK26 PTHR24223:SF241 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 transmembrane transporter activity#GO:0022857;xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;amide transmembrane transporter activity#GO:0042887;oligopeptide transmembrane transporter activity#GO:0035673;peptide transmembrane transporter activity#GO:1904680;organic anion transmembrane transporter activity#GO:0008514;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;oligopeptide transport#GO:0006857;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;peptide transport#GO:0015833;cellular process#GO:0009987 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004003.1|UniProtKB=W5M8R7 W5M8R7 BOLL PTHR11176:SF10 BOULE-RELATED PROTEIN BOULE-LIKE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of translational initiation#GO:0006446;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017074.1|UniProtKB=W5NKE6 W5NKE6 PTHR23406:SF17 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;dicarboxylic acid metabolic process#GO:0043648;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Malic enzyme#P03136 LEPOC|Ensembl=ENSLOCG00000008500.1|UniProtKB=W5MPN9 W5MPN9 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010161.1|UniProtKB=W5MVN1 W5MVN1 PTHR24216:SF11 PAXILLIN-RELATED PAXILLIN signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;substrate adhesion-dependent cell spreading#GO:0034446;ameboidal-type cell migration#GO:0001667;cell adhesion#GO:0007155;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;endothelial cell migration#GO:0043542;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell migration#GO:0016477;signaling#GO:0023052 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CCKR signaling map#P06959>Paxillin#P07145;Angiogenesis#P00005>Paxillin#P00194;Gonadotropin-releasing hormone receptor pathway#P06664>Paxillin#P06784;VEGF signaling pathway#P00056>Paxillin#P01418;Integrin signalling pathway#P00034>Paxillin#P00950 LEPOC|Ensembl=ENSLOCG00000015399.1|UniProtKB=W5NE90 W5NE90 PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 LEPOC|Ensembl=ENSLOCG00000005158.1|UniProtKB=W5MCV5 W5MCV5 PTHR24086:SF48 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A FF1D-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002541.1|UniProtKB=W5M3M6 W5M3M6 PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 DPP signaling pathway#P06213>TSG#P06287;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258 LEPOC|Ensembl=ENSLOCG00000010856.1|UniProtKB=W5MY51 W5MY51 PTHR24347:SF18 SERINE/THREONINE-PROTEIN KINASE CAM KINASE-LIKE VESICLE-ASSOCIATED PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003208.1|UniProtKB=W5M5Y9 W5M5Y9 PTHR22382:SF7 RIKEN CDNA 4921504E06 GENE RIKEN CDNA 4921504E06 GENE LEPOC|Ensembl=ENSLOCG00000006766.1|UniProtKB=W5MIG7 W5MIG7 PTHR14233:SF12 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F2 LEPOC|Ensembl=ENSLOCG00000005088.1|UniProtKB=W5MCL7 W5MCL7 PTHR22776:SF3 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010972.1|UniProtKB=W5MYJ9 W5MYJ9 PTHR24390:SF265 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 239-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006792.1|UniProtKB=W5MIM1 W5MIM1 PTHR12039:SF21 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 1 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000010324.1|UniProtKB=W5MW92 W5MW92 PTHR34523:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 LEPOC|Ensembl=ENSLOCG00000009867.1|UniProtKB=W5MUK1 W5MUK1 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009896.1|UniProtKB=W5MUP5 W5MUP5 PTHR45739:SF3 MATRIX PROTEIN, PUTATIVE-RELATED FRAS-RELATED EXTRACELLULAR MATRIX PROTEIN 1B PRECURSOR anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002826.1|UniProtKB=W5M4M2 W5M4M2 PTHR10972:SF46 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 11 binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013615.1|UniProtKB=W5N824 W5N824 PTHR11683:SF4 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-A cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;filopodium#GO:0030175;neuronal cell body#GO:0043025;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axonal growth cone#GO:0044295;cell body#GO:0044297;neuron projection#GO:0043005;distal axon#GO:0150034;cell projection#GO:0042995;growth cone#GO:0030426;site of polarized growth#GO:0030427;plasma membrane#GO:0005886 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000018271.1|UniProtKB=W5NP13 W5NP13 PTHR11984:SF118 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000010107.1|UniProtKB=W5MVF9 W5MVF9 PTHR15177:SF2 G-PROTEIN COUPLED RECEPTOR 143 G-PROTEIN COUPLED RECEPTOR 143 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016482.1|UniProtKB=W5NIA3 W5NIA3 PTHR22948:SF15 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 6 negative regulation of gene expression#GO:0010629;male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;regulatory ncRNA processing#GO:0070918;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;piRNA processing#GO:0034587;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;multicellular organism development#GO:0007275;regionalization#GO:0003002;oogenesis#GO:0048477;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008485.1|UniProtKB=W5MPL9 W5MPL9 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000003106.1|UniProtKB=W5M5J8 W5M5J8 PTHR10114:SF0 60S RIBOSOMAL PROTEIN L36 LARGE RIBOSOMAL SUBUNIT PROTEIN EL36 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001451.1|UniProtKB=W5LZU6 W5LZU6 PTHR45640:SF5 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN B CHAIN protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 negative regulation of biological process#GO:0048519;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;protein folding#GO:0006457;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000004636.1|UniProtKB=W5MAZ9 W5MAZ9 PTHR24409:SF363 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN CONTAINING 32 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013456.1|UniProtKB=W5N7H9 W5N7H9 PTHR37558:SF1 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009309.1|UniProtKB=W5MSJ6 W5MSJ6 PTHR16435:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000017898.1|UniProtKB=W5NMZ2 W5NMZ2 PTHR22923:SF87 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011423.1|UniProtKB=W5N080 W5N080 PTHR24347:SF442 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016667.1|UniProtKB=W5NIX9 W5NIX9 C12orf4 PTHR16525:SF0 PROTEIN C12ORF4 PROTEIN C12ORF4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012627.1|UniProtKB=W5N4J4 W5N4J4 PTHR23036:SF95 CYTOKINE RECEPTOR ONCOSTATIN-M-SPECIFIC RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011969.1|UniProtKB=W5N258 W5N258 PTHR12429:SF13 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;neuron to neuron synapse#GO:0098984;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 LEPOC|Ensembl=ENSLOCG00000007795.1|UniProtKB=W5MM69 W5MM69 LDLR PTHR24270:SF21 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR protein-containing complex binding#GO:0044877;cargo receptor activity#GO:0038024;lipoprotein particle binding#GO:0071813;protein-lipid complex binding#GO:0071814;binding#GO:0005488;low-density lipoprotein particle receptor activity#GO:0005041 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;endocytosis#GO:0006897;intracellular sterol transport#GO:0032366;vesicle-mediated transport#GO:0016192;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cholesterol homeostasis#GO:0042632;lipid transport#GO:0006869;localization#GO:0051179;intracellular cholesterol transport#GO:0032367;organic substance transport#GO:0071702;cholesterol transport#GO:0030301;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;establishment of localization in cell#GO:0051649;lipid localization#GO:0010876;intracellular transport#GO:0046907;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;intracellular lipid transport#GO:0032365 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000012367.1|UniProtKB=W5N3L2 W5N3L2 PTHR45930:SF2 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017216.1|UniProtKB=W5NKX6 W5NKX6 PTHR10816:SF11 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007411.1|UniProtKB=W5MKU0 W5MKU0 HSF1 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005741.1|UniProtKB=W5MEX6 W5MEX6 PHLDB3 PTHR12156:SF22 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 3 LEPOC|Ensembl=ENSLOCG00000004854.1|UniProtKB=W5MBS0 W5MBS0 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000014141.1|UniProtKB=W5N9W1 W5N9W1 PTHR14198:SF4 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 5 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013633.1|UniProtKB=W5N847 W5N847 PTHR12107:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-4 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;channel regulator activity#GO:0016247;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;system process#GO:0003008;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;receptor-mediated endocytosis#GO:0006898;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;protein localization to organelle#GO:0033365;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;positive regulation of biological process#GO:0048518;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;vacuolar transport#GO:0007034;endocytosis#GO:0006897;protein localization to vacuole#GO:0072665;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;positive regulation of synaptic transmission#GO:0050806;import into cell#GO:0098657;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000012382.1|UniProtKB=W5N3N8 W5N3N8 PTHR14076:SF10 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RAMP2 PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;monoatomic cation transport#GO:0006812;vasculature development#GO:0001944;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;protein localization to plasma membrane#GO:0072659;response to organic substance#GO:0010033;localization within membrane#GO:0051668;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;multicellular organism development#GO:0007275;tube development#GO:0035295;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;import into cell#GO:0098657 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018274.1|UniProtKB=W5NP16 W5NP16 GJB3 PTHR11984:SF65 CONNEXIN GAP JUNCTION BETA-3 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000016742.1|UniProtKB=W5NJ81 W5NJ81 PTHR10256:SF2 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008116.1|UniProtKB=W5MN99 W5MN99 PTHR22804:SF8 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000003371.1|UniProtKB=W5M6H0 W5M6H0 PTHR21162:SF0 P53 AND DNA DAMAGE-REGULATED PROTEIN P53 AND DNA DAMAGE-REGULATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011329.1|UniProtKB=W5MZX3 W5MZX3 DIAPH1 PTHR45691:SF4 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 LEPOC|Ensembl=ENSLOCG00000006133.1|UniProtKB=W5MGA3 W5MGA3 PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003764.1|UniProtKB=W5M7Y1 W5M7Y1 PTHR10177:SF60 CYCLINS CYCLIN-G2 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000012023.1|UniProtKB=W5N2E4 W5N2E4 PTHR24093:SF435 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 4 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005499.1|UniProtKB=W5ME33 W5ME33 PTHR11567:SF180 ACID PHOSPHATASE-RELATED LYSOSOMAL ACID PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;lytic vacuole organization#GO:0080171;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013337.1|UniProtKB=W5N732 W5N732 VAMP2 PTHR45701:SF5 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 2 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Circadian clock system#P00015>Per#P00504;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Circadian clock system#P00015>per#G01503;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Circadian clock system#P00015>per#G01499;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000016450.1|UniProtKB=W5NI63 W5NI63 PTHR45740:SF15 POLY [ADP-RIBOSE] POLYMERASE ZINC FINGER CCCH TYPE DOMAIN CONTAINING 1-LIKE transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007195.1|UniProtKB=W5MK02 W5MK02 PTHR20837:SF2 CENTROSOMAL PROTEIN-RELATED PROTEIN CC2D2B cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000004379.1|UniProtKB=W5MA30 W5MA30 PTHR24416:SF390 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001322.1|UniProtKB=W5LZE5 W5LZE5 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014142.1|UniProtKB=W5N9W2 W5N9W2 PTHR13005:SF3 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000010426.1|UniProtKB=W5MWM6 W5MWM6 PTHR14398:SF1 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 27 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016489.1|UniProtKB=W5NIB3 W5NIB3 PTHR10127:SF824 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT ALPHA hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018046.1|UniProtKB=W5NND8 W5NND8 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009807.1|UniProtKB=W5MUD7 W5MUD7 PTHR18966:SF157 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 LEPOC|Ensembl=ENSLOCG00000010460.1|UniProtKB=W5MWR1 W5MWR1 PTHR22808:SF8 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE, MITOCHONDRIAL methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016776.1|UniProtKB=W5NJC6 W5NJC6 PTHR11711:SF459 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000014879.1|UniProtKB=W5NCG5 W5NCG5 PTHR31882:SF9 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER SI:CH211-153B23.7 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to lipopolysaccharide#GO:0071222;regulation of transcription by RNA polymerase II#GO:0006357;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;response to lipopolysaccharide#GO:0032496;cellular response to molecule of bacterial origin#GO:0071219;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000015894.1|UniProtKB=W5NG12 W5NG12 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN UL30-LIKE structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009596.1|UniProtKB=W5MTL2 W5MTL2 C3orf70 PTHR31785:SF2 UPF0524 PROTEIN C3ORF70 UPF0524 PROTEIN C3ORF70 system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000012862.1|UniProtKB=W5N5D0 W5N5D0 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000002900.1|UniProtKB=W5M4Y7 W5M4Y7 PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1 LEPOC|Ensembl=ENSLOCG00000006750.1|UniProtKB=W5MIF6 W5MIF6 PTHR10166:SF68 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VWFA AND CACHE DOMAIN-CONTAINING PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000000364.1|UniProtKB=W5LWA6 W5LWA6 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003885.1|UniProtKB=W5M8E0 W5M8E0 COL9A3 PTHR24023:SF1073 COLLAGEN ALPHA COLLAGEN ALPHA-3(IX) CHAIN PRECURSOR structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000017167.1|UniProtKB=W5NKR1 W5NKR1 PTHR15189:SF7 BRISC AND BRCA1-A COMPLEX MEMBER 2 BRISC AND BRCA1-A COMPLEX MEMBER 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;BRCA1-A complex#GO:0070531;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001220.1|UniProtKB=W5LZ20 W5LZ20 PTHR22750:SF2 G-PROTEIN COUPLED RECEPTOR MELANOCYTE-STIMULATING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004314.1|UniProtKB=W5M9U6 W5M9U6 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008407.1|UniProtKB=W5MPD0 W5MPD0 PTHR24212:SF1 ZYXIN/TRIP6 ZYXIN cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052 actomyosin#GO:0042641;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011667.1|UniProtKB=W5N129 W5N129 PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000001804.1|UniProtKB=W5M135 W5M135 PTHR14463:SF10 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 1 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008180.1|UniProtKB=W5MNJ1 W5MNJ1 PTHR12195:SF4 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;generation of neurons#GO:0048699;plasma membrane bounded cell projection assembly#GO:0120031;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;synapse#GO:0045202;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 LEPOC|Ensembl=ENSLOCG00000014441.1|UniProtKB=W5NAX6 W5NAX6 PTHR23182:SF6 BREAKPOINT CLUSTER REGION PROTEIN BCR ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN-LIKE cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000007.1|UniProtKB=W5LV51 W5LV51 PTHR13904:SF0 PRE-MRNA SPLICING FACTOR PRP31 U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013628.1|UniProtKB=W5N843 W5N843 PTHR15025:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;calcium channel complex#GO:0034704;cation channel complex#GO:0034703;sarcolemma#GO:0042383;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016426.1|UniProtKB=W5NI34 W5NI34 PTHR12308:SF21 ANOCTAMIN ANOCTAMIN-6 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;membrane organization#GO:0061024;monoatomic anion transmembrane transport#GO:0098656;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;chloride transmembrane transport#GO:1902476;chloride transport#GO:0006821;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014217.1|UniProtKB=W5NA50 W5NA50 PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 dehydrogenase#PC00092;oxidoreductase#PC00176 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 LEPOC|Ensembl=ENSLOCG00000001208.1|UniProtKB=W5LZ02 W5LZ02 PTHR12080:SF80 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014216.1|UniProtKB=W5NA51 W5NA51 PTHR14113:SF1 PICCOLO/BASSOON PROTEIN BASSOON structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to synapse#GO:0035418;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;cytoskeleton#GO:0005856;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000004168.1|UniProtKB=W5M9D1 W5M9D1 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016964.1|UniProtKB=W5NK18 W5NK18 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008398.1|UniProtKB=W5MPA6 W5MPA6 PTHR24347:SF401 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK1 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010892.1|UniProtKB=W5MY96 W5MY96 PTHR11783:SF64 SULFOTRANSFERASE SULT SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010325.1|UniProtKB=W5MW93 W5MW93 PTHR24280:SF4 CYTOCHROME P450 20A1 CYTOCHROME P450 20A1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000011096.1|UniProtKB=W5MZ19 W5MZ19 PTHR24241:SF133 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OXYTOCIN RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;response to organic substance#GO:0010033;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010464.1|UniProtKB=W5MWR4 W5MWR4 PTHR12982:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001838.1|UniProtKB=W5M172 W5M172 PTHR11852:SF1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001564.1|UniProtKB=W5M0C9 W5M0C9 PTHR22988:SF71 MYOTONIC DYSTROPHY S/T KINASE-RELATED CITRON RHO-INTERACTING KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005787.1|UniProtKB=W5MF27 W5MF27 PTHR24388:SF96 ZINC FINGER PROTEIN GENE, 32687-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005999.1|UniProtKB=W5MFU1 W5MFU1 PTHR46712:SF1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 LEPOC|Ensembl=ENSLOCG00000009601.1|UniProtKB=W5MTM9 W5MTM9 PTHR12616:SF8 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006812.1|UniProtKB=W5MIP4 W5MIP4 PTHR47968:SF75 CENTROMERE PROTEIN E CENTROMERE-ASSOCIATED PROTEIN E LEPOC|Ensembl=ENSLOCG00000002807.1|UniProtKB=W5M4J4 W5M4J4 CCP110 PTHR13594:SF3 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA-LIKE ISOFORM X3 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;centriole assembly#GO:0098534;cell projection organization#GO:0030030;negative regulation of cell cycle#GO:0045786;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;negative regulation of cell cycle process#GO:0010948;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;plasma membrane bounded cell projection organization#GO:0120036;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;non-membrane-bounded organelle assembly#GO:0140694;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001377.1|UniProtKB=W5LZK2 W5LZK2 PTHR23266:SF390 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013494.1|UniProtKB=W5N7N3 W5N7N3 PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 1 nucleotide binding#GO:0000166;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001577.1|UniProtKB=W5M0A1 W5M0A1 PTHR46198:SF1 PROTEIN-TYROSINE-PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 5 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cell junction#GO:0030054;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008297.1|UniProtKB=W5MNX3 W5MNX3 PTHR10686:SF38 FOLATE TRANSPORTER THIAMINE TRANSPORTER 2 ISOFORM X1 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006786.1|UniProtKB=W5MIJ1 W5MIJ1 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002639.1|UniProtKB=W5M3Z4 W5M3Z4 PTHR12977:SF4 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B LEPOC|Ensembl=ENSLOCG00000015618.1|UniProtKB=W5NF18 W5NF18 PTHR48277:SF1 MITOCHONDRIAL RIBOSOMAL PROTEIN S5 MITOCHONDRIAL RIBOSOMAL PROTEIN S5 LEPOC|Ensembl=ENSLOCG00000014071.1|UniProtKB=W5N9N4 W5N9N4 PTHR12378:SF41 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 2-LIKE ISOFORM X1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005899.1|UniProtKB=W5MFG9 W5MFG9 JMY PTHR23330:SF8 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED JUNCTION-MEDIATING AND -REGULATORY PROTEIN transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 signal transduction#GO:0007165;signal transduction by p53 class mediator#GO:0072331;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;apoptotic process#GO:0006915;cell death#GO:0008219;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;intrinsic apoptotic signaling pathway#GO:0097193;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009212.1|UniProtKB=W5MS76 W5MS76 PTHR11871:SF1 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000009987.1|UniProtKB=W5MV04 W5MV04 PTHR11158:SF23 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3A phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000016044.1|UniProtKB=W5NGL3 W5NGL3 PTHR10574:SF274 NETRIN/LAMININ-RELATED USHERIN animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000011683.1|UniProtKB=W5N174 W5N174 PTHR10972:SF15 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 3 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 envelope#GO:0031975;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000007015.1|UniProtKB=W5MJE0 W5MJE0 PTHR14009:SF8 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018177.1|UniProtKB=W5NNR9 W5NNR9 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003629.1|UniProtKB=W5M7F2 W5M7F2 SH2D5 PTHR15832:SF3 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG SH2 DOMAIN-CONTAINING PROTEIN 5 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;asymmetric synapse#GO:0032279 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010140.1|UniProtKB=W5MVK3 W5MVK3 PTHR11607:SF28 ALPHA-MANNOSIDASE EPIDIDYMIS-SPECIFIC ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003668.1|UniProtKB=W5M7M8 W5M7M8 PTHR11339:SF244 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED IGGFC-BINDING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000003337.1|UniProtKB=W5M6G9 W5M6G9 PTHR45761:SF4 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-3 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001814.1|UniProtKB=W5M150 W5M150 PTHR11905:SF38 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 33 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001931.1|UniProtKB=W5M1I0 W5M1I0 PTHR11576:SF15 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3-LIKE enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003790.1|UniProtKB=W5M830 W5M830 PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;heterocycle biosynthetic process#GO:0018130;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pyridine-containing compound metabolic process#GO:0072524;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122 LEPOC|Ensembl=ENSLOCG00000010477.1|UniProtKB=W5MWV0 W5MWV0 PTHR46877:SF12 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000005231.1|UniProtKB=W5MD39 W5MD39 PTHR31525:SF1 HEME TRANSPORTER HRG1 HEME TRANSPORTER HRG1 tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006190.1|UniProtKB=W5MGG8 W5MGG8 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002928.1|UniProtKB=W5M4Y9 W5M4Y9 ZNF276 PTHR24409:SF345 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN CONTAINING 41 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012344.1|UniProtKB=W5N3K0 W5N3K0 PTHR24166:SF21 ROLLING PEBBLES, ISOFORM B PROTEIN TANC2 regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of synapse structure or activity#GO:0050803;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of postsynapse organization#GO:0099175;regulation of neuron projection development#GO:0010975 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;dendritic spine#GO:0043197 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002203.1|UniProtKB=W5M2F3 W5M2F3 PTHR31195:SF2 GEO02494P1 GEO02494P1 LEPOC|Ensembl=ENSLOCG00000003370.1|UniProtKB=W5M6H9 W5M6H9 PTHR12396:SF5 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 2 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;heterochromatin formation#GO:0031507;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;DNA methylation-dependent heterochromatin formation#GO:0006346;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016758.1|UniProtKB=W5NJB0 W5NJB0 PTHR42693:SF11 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009933.1|UniProtKB=W5MUT5 W5MUT5 EXOG PTHR13966:SF19 ENDONUCLEASE RELATED NUCLEASE EXOG, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;execution phase of apoptosis#GO:0097194;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;cellular component disassembly#GO:0022411;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000559.1|UniProtKB=W5LWW3 W5LWW3 PTHR19282:SF168 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001519.1|UniProtKB=W5M050 W5M050 PTHR10155:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;response to insulin#GO:0032868;phosphatidylinositol biosynthetic process#GO:0006661;response to peptide hormone#GO:0043434;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;glycerophospholipid biosynthetic process#GO:0046474;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p85#P01202;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 LEPOC|Ensembl=ENSLOCG00000018030.1|UniProtKB=W5NNC2 W5NNC2 PTHR46890:SF29 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000003145.1|UniProtKB=W5M5P7 W5M5P7 PTHR33722:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT DELTA sperm capacitation#GO:0048240;germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cilium-dependent cell motility#GO:0060285;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;sperm flagellum#GO:0036126;voltage-gated calcium channel complex#GO:0005891;sperm principal piece#GO:0097228;CatSper complex#GO:0036128;motile cilium#GO:0031514;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;9+2 motile cilium#GO:0097729;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013344.1|UniProtKB=W5N754 W5N754 PTHR11269:SF8 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to abiotic stimulus#GO:0009628;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>Per#P00504;Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06895;Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06681;Circadian clock system#P00015>per#G01499 LEPOC|Ensembl=ENSLOCG00000000510.1|UniProtKB=W5LWS8 W5LWS8 PTHR12776:SF1 KAZRIN-RELATED KAZRIN LEPOC|Ensembl=ENSLOCG00000014918.1|UniProtKB=W5NCK8 W5NCK8 PTHR45963:SF3 RE52028P SORTING NEXIN-12 phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000002037.1|UniProtKB=W5M1V1 W5M1V1 PTHR12039:SF18 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 2 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000013784.1|UniProtKB=W5N8P5 W5N8P5 PTHR12002:SF78 CLAUDIN CLAUDIN-7 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000003070.1|UniProtKB=W5M5F8 W5M5F8 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009522.1|UniProtKB=W5MTD2 W5MTD2 PTHR22855:SF47 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014191.1|UniProtKB=W5NA22 W5NA22 PTHR12027:SF33 WNT RELATED PROTEIN WNT-5A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000017875.1|UniProtKB=W5NMW9 W5NMW9 PTHR11636:SF115 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003086.1|UniProtKB=W5M5I2 W5M5I2 PTHR45721:SF2 LAMIN DM0-RELATED LAMIN-B2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;nuclear migration#GO:0007097;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;establishment of organelle localization#GO:0051656;negative regulation of cellular process#GO:0048523;localization within membrane#GO:0051668;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular macromolecule localization#GO:0070727;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;chromatin organization#GO:0006325;intracellular transport#GO:0046907;nuclear envelope organization#GO:0006998;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;protein-containing complex localization#GO:0031503 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear periphery#GO:0034399;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 FAS signaling pathway#P00020>Nuclear Lamin#P00616 LEPOC|Ensembl=ENSLOCG00000016741.1|UniProtKB=W5NJ84 W5NJ84 PTHR11685:SF234 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING RBR-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006680.1|UniProtKB=W5MI52 W5MI52 PTHR20913:SF10 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE TBC1 DOMAIN FAMILY MEMBER 20 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000000325.1|UniProtKB=W5LW46 W5LW46 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005282.1|UniProtKB=W5MDA4 W5MDA4 PTHR31564:SF0 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 supramolecular complex#GO:0099080;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytosol#GO:0005829;anaphase-promoting complex#GO:0005680;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000015828.1|UniProtKB=W5NFS6 W5NFS6 PTHR12907:SF4 EGL NINE HOMOLOG-RELATED EGL NINE HOMOLOG 1 cation binding#GO:0043169;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 response to hypoxia#GO:0001666;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein hydroxylation#GO:0018126;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to oxygen levels#GO:0070482;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 LEPOC|Ensembl=ENSLOCG00000006221.1|UniProtKB=W5MGK3 W5MGK3 PTHR45996:SF1 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000002575.1|UniProtKB=W5M3T4 W5M3T4 PTHR12349:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC8 palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000008792.1|UniProtKB=W5MQP3 W5MQP3 PTHR31613:SF2 AUGURIN AUGURIN developmental process#GO:0032502;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;nervous system development#GO:0007399;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;central nervous system development#GO:0007417;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;anaphase-promoting complex-dependent catabolic process#GO:0031145;response to stress#GO:0006950;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005912.1|UniProtKB=W5MFI2 W5MFI2 PTHR15263:SF1 I-KAPPA-B-LIKE PROTEIN IKBL NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 B cell activation#P00010>I kappa B#P00392 LEPOC|Ensembl=ENSLOCG00000011157.1|UniProtKB=W5MZA2 W5MZA2 PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;inorganic molecular entity transmembrane transporter activity#GO:0015318;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;ATP binding#GO:0005524;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>F1 alpha#P02791 LEPOC|Ensembl=ENSLOCG00000017502.1|UniProtKB=W5NLU8 W5NLU8 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015316.1|UniProtKB=W5NDY9 W5NDY9 PTHR10672:SF6 ADDUCIN BETA-ADDUCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;postsynapse#GO:0098794;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003427.1|UniProtKB=W5M6Q2 W5M6Q2 PTHR10545:SF36 DIAMINE N-ACETYLTRANSFERASE DIAMINE ACETYLTRANSFERASE 1 cation binding#GO:0043169;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ion binding#GO:0043167;N-acyltransferase activity#GO:0016410 organonitrogen compound metabolic process#GO:1901564;amine metabolic process#GO:0009308;nitrogen compound metabolic process#GO:0006807;polyamine metabolic process#GO:0006595;biogenic amine metabolic process#GO:0006576;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000006095.1|UniProtKB=W5MG52 W5MG52 PTHR10083:SF377 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007063.1|UniProtKB=W5MJP0 W5MJP0 PTHR13140:SF255 MYOSIN UNCONVENTIONAL MYOSIN-IC microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 actin filament-based movement#GO:0030048;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000013769.1|UniProtKB=W5N8L9 W5N8L9 EIF3J PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000838.1|UniProtKB=W5LXU8 W5LXU8 PTHR24006:SF666 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 25 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004756.1|UniProtKB=W5MBE9 W5MBE9 PTHR12505:SF21 PHD FINGER TRANSCRIPTION FACTOR TRINUCLEOTIDE REPEAT-CONTAINING GENE 18 PROTEIN DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000000465.1|UniProtKB=W5LWK0 W5LWK0 USB1 PTHR13522:SF3 U6 SNRNA PHOSPHODIESTERASE 1 U6 SNRNA PHOSPHODIESTERASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007678.1|UniProtKB=W5MLS0 W5MLS0 PTHR24115:SF546 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF14 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016919.1|UniProtKB=W5NJV6 W5NJV6 PTHR21245:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015034.1|UniProtKB=W5NCZ4 W5NCZ4 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001036.1|UniProtKB=W5LYH1 W5LYH1 PTHR11590:SF80 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE TRANSGLUTAMINASE 5,-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007897.1|UniProtKB=W5MMI1 W5MMI1 PTHR21456:SF3 FAMILY WITH SEQUENCE SIMILARITY 102 EEIG FAMILY MEMBER 2 LEPOC|Ensembl=ENSLOCG00000010723.1|UniProtKB=W5MXN5 W5MXN5 PTHR15751:SF13 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;nervous system development#GO:0007399;establishment of protein localization#GO:0045184;axo-dendritic transport#GO:0008088;system development#GO:0048731;cell differentiation#GO:0030154;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;mitochondrion organization#GO:0007005;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;dendrite#GO:0030425;mitochondrion#GO:0005739;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012084.1|UniProtKB=W5N2L5 W5N2L5 PTHR12752:SF5 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6 LEPOC|Ensembl=ENSLOCG00000010020.1|UniProtKB=W5MV92 W5MV92 PTHR46708:SF8 TENASCIN FIBRONECTIN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;cell-substrate junction assembly#GO:0007044;system development#GO:0048731;cell-matrix adhesion#GO:0007160;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Fibronectin#P00939 LEPOC|Ensembl=ENSLOCG00000017763.1|UniProtKB=W5NMK8 W5NMK8 PTHR17068:SF3 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER LEPOC|Ensembl=ENSLOCG00000009797.1|UniProtKB=W5MUB4 W5MUB4 PTHR12021:SF5 THYMOSIN BETA THYMOSIN BETA 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 negative regulation of protein polymerization#GO:0032272;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell migration#GO:0030334;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005845.1|UniProtKB=W5MF98 W5MF98 PTHR19969:SF18 SH2-SH3 ADAPTOR PROTEIN-RELATED GRB2 RELATED ADAPTOR PROTEIN molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014174.1|UniProtKB=W5NA08 W5NA08 PTHR35478:SF1 ZINC FINGER FYVE DOMAIN PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 LEPOC|Ensembl=ENSLOCG00000006666.1|UniProtKB=W5MI43 W5MI43 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016367.1|UniProtKB=W5NHV1 W5NHV1 PTHR23179:SF26 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED T-CELL ACTIVATION RHO GTPASE-ACTIVATING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000013710.1|UniProtKB=W5N8E5 W5N8E5 PTHR10696:SF51 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000013097.1|UniProtKB=W5N675 W5N675 PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003896.1|UniProtKB=W5M8E4 W5M8E4 PTHR10543:SF110 BETA-CAROTENE DIOXYGENASE BETA-CAROTENE 15,15'-MONOOXYGENASE 1 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;isoprenoid catabolic process#GO:0008300;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;terpenoid metabolic process#GO:0006721 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011876.1|UniProtKB=W5N1W1 W5N1W1 PTHR22576:SF40 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006788.1|UniProtKB=W5MIK1 W5MIK1 PTHR11802:SF502 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE LYSOSOMAL PROTECTIVE PROTEIN hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002699.1|UniProtKB=W5M465 W5M465 PTHR16079:SF4 UBIQUITIN LIGASE PROTEIN CHFR E3 UBIQUITIN-PROTEIN LIGASE CHFR ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008898.1|UniProtKB=W5MR23 W5MR23 PTHR13094:SF1 NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011845.1|UniProtKB=W5N1R7 W5N1R7 PTHR18914:SF24 ALPHA CATENIN CATENIN ALPHA-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;beta-catenin binding#GO:0008013;actin filament binding#GO:0051015 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Wnt signaling pathway#P00057>alpha-catenin#P01471;Cadherin signaling pathway#P00012>alpha-catenin#P00467 LEPOC|Ensembl=ENSLOCG00000000732.1|UniProtKB=W5LXF7 W5LXF7 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016957.1|UniProtKB=W5NK04 W5NK04 PTHR24189:SF69 MYOTROPHIN MYOTROPHIN regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000815.1|UniProtKB=W5LXQ3 W5LXQ3 PTHR15185:SF3 BCL9 B-CELL CLL_LYMPHOMA 9-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006846.1|UniProtKB=W5MIT5 W5MIT5 PTHR24082:SF210 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;intracellular receptor signaling pathway#GO:0030522;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012684.1|UniProtKB=W5N4Q3 W5N4Q3 PTHR13986:SF4 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT ENDOPLASMIC RETICULUM PROTEIN SC65 collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;binding#GO:0005488 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;protein hydroxylation#GO:0018126;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011949.1|UniProtKB=W5N243 W5N243 PTHR11468:SF3 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, LIVER FORM transferase activity#GO:0016740;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 LEPOC|Ensembl=ENSLOCG00000004172.1|UniProtKB=W5M9D8 W5M9D8 PTHR15856:SF27 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000009458.1|UniProtKB=W5MT50 W5MT50 PTHR23421:SF50 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 galactosidase#PC00104;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017314.1|UniProtKB=W5NLB0 W5NLB0 C11orf96 PTHR40250:SF1 CHROMOSOME 11 OPEN READING FRAME 96 SI:CH1073-281M9.1 LEPOC|Ensembl=ENSLOCG00000006201.1|UniProtKB=W5MGI1 W5MGI1 PTHR23291:SF18 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 2 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008267.1|UniProtKB=W5MNS7 W5MNS7 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001114.1|UniProtKB=W5LYR5 W5LYR5 PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014244.1|UniProtKB=W5NA78 W5NA78 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000002008.1|UniProtKB=W5M1S8 W5M1S8 PTHR44188:SF2 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1-LIKE 1 mitochondrial fusion#GO:0008053;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000009274.1|UniProtKB=W5MSF4 W5MSF4 PTHR33442:SF1 TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000006337.1|UniProtKB=W5MGZ5 W5MGZ5 PTHR24350:SF5 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE A mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;spindle organization#GO:0007051;regulation of cytokinesis#GO:0032465 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008699.1|UniProtKB=W5MQC0 W5MQC0 PTHR11046:SF15 OLIGORIBONUCLEASE, MITOCHONDRIAL RIBOFLAVIN TRANSPORTER 1 ISOFORM X1 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004550.1|UniProtKB=W5MAN1 W5MAN1 PTHR15315:SF26 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 LEPOC|Ensembl=ENSLOCG00000006616.1|UniProtKB=W5MHZ7 W5MHZ7 PTHR12308:SF23 ANOCTAMIN ANOCTAMIN-5 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017490.1|UniProtKB=W5NLT6 W5NLT6 PTHR19957:SF72 SYNTAXIN SYNTAXIN-3-LIKE molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;export from cell#GO:0140352;secretion by cell#GO:0032940;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000010588.1|UniProtKB=W5MX69 W5MX69 PTHR11848:SF34 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-3 PROPROTEIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;regulation of cell population proliferation#GO:0042127;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000015385.1|UniProtKB=W5NE73 W5NE73 PTHR43128:SF2 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007486.1|UniProtKB=W5ML33 W5ML33 PTHR12157:SF26 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS 4 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006241.1|UniProtKB=W5MGM8 W5MGM8 PTHR20963:SF8 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000011813.1|UniProtKB=W5N1L9 W5N1L9 PTHR10671:SF40 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017014.1|UniProtKB=W5NK73 W5NK73 PTHR45915:SF4 TRANSCRIPTION INTERMEDIARY FACTOR TRANSCRIPTION INTERMEDIARY FACTOR 1-ALPHA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004064.1|UniProtKB=W5M905 W5M905 PTHR13026:SF0 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING 1B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005042.1|UniProtKB=W5MCG7 W5MCG7 PTHR13723:SF24 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 14 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017900.1|UniProtKB=W5NMZ4 W5NMZ4 PTHR19282:SF51 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017358.1|UniProtKB=W5NLF4 W5NLF4 PTHR33663:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 COILED-COIL DOMAIN-CONTAINING PROTEIN 185 LEPOC|Ensembl=ENSLOCG00000007713.1|UniProtKB=W5MLV6 W5MLV6 DEPDC1B PTHR16206:SF11 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1B scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002761.1|UniProtKB=W5M4D8 W5M4D8 PTHR45632:SF4 LD33804P KELCH-LIKE PROTEIN 36 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015861.1|UniProtKB=W5NFW9 W5NFW9 PTHR11769:SF9 HYALURONIDASE HYALURONIDASE glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008476.1|UniProtKB=W5MPP0 W5MPP0 PTHR23345:SF29 VITELLOGENIN-RELATED VITELLOGENIN 3, PHOSVITINLESS transporter activity#GO:0005215;lipid transporter activity#GO:0005319 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cellular process#GO:0009987;response to estradiol#GO:0032355 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000003780.1|UniProtKB=W5M818 W5M818 PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 LEPOC|Ensembl=ENSLOCG00000014412.1|UniProtKB=W5NAT2 W5NAT2 PTHR15907:SF34 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006175.1|UniProtKB=W5MGF0 W5MGF0 PAAF1 PTHR19879:SF7 TRANSCRIPTION INITIATION FACTOR TFIID PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010001.1|UniProtKB=W5MV19 W5MV19 PTHR11960:SF66 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007462.1|UniProtKB=W5MKZ8 W5MKZ8 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG PROTEIN HGH1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000013759.1|UniProtKB=W5N8L3 W5N8L3 PTHR18945:SF477 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000004463.1|UniProtKB=W5MAC3 W5MAC3 PTHR10985:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION COFACTOR HES-6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000011985.1|UniProtKB=W5N279 W5N279 NIPAL1 PTHR12570:SF13 FAMILY NOT NAMED MAGNESIUM TRANSPORTER NIPA3 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011455.1|UniProtKB=W5N0B5 W5N0B5 PTHR23509:SF4 PA-PL1 PHOSPHOLIPASE FAMILY SEC23-INTERACTING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014215.1|UniProtKB=W5NA90 W5NA90 PTHR23317:SF81 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 11 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of catalytic activity#GO:0050790;regulation of filopodium assembly#GO:0051489;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of hydrolase activity#GO:0051336;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000005981.1|UniProtKB=W5MFS0 W5MFS0 PTHR11886:SF113 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 2, CYTOPLASMIC protein binding#GO:0005515;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000005283.1|UniProtKB=W5MDC3 W5MDC3 ODF2L PTHR23162:SF7 OUTER DENSE FIBER OF SPERM TAILS 2 PROTEIN BCAP negative regulation of biological process#GO:0048519;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of organelle assembly#GO:1902115;negative regulation of organelle organization#GO:0010639;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011858.1|UniProtKB=W5N1S3 W5N1S3 PTHR12019:SF22 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN LAMINA-ASSOCIATED POLYPEPTIDE 2, ISOFORMS BETA_GAMMA peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000007849.1|UniProtKB=W5MMC1 W5MMC1 PTHR11972:SF60 NADPH OXIDASE CYTOCHROME B-245 HEAVY CHAIN oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013564.1|UniProtKB=W5N7W5 W5N7W5 PTHR11315:SF10 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE FOLATE GAMMA-GLUTAMYL HYDROLASE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015295.1|UniProtKB=W5NDV9 W5NDV9 PTHR13217:SF6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 LEPOC|Ensembl=ENSLOCG00000013767.1|UniProtKB=W5N8L8 W5N8L8 PTHR23412:SF19 STEREOCILIN RELATED STEREOCILIN 1 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007751.1|UniProtKB=W5MM04 W5MM04 PTHR19863:SF5 NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG WD REPEAT-CONTAINING PROTEIN 47 LEPOC|Ensembl=ENSLOCG00000003981.1|UniProtKB=W5M8P3 W5M8P3 PTHR13593:SF32 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 LEPOC|Ensembl=ENSLOCG00000001446.1|UniProtKB=W5LZU1 W5LZU1 PTHR23411:SF35 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT MU protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;humoral immune response#GO:0006959;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;antibacterial humoral response#GO:0019731;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;defense response to bacterium#GO:0042742;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;complement activation#GO:0006956 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 immunoglobulin receptor superfamily#PC00124 B cell activation#P00010>mIgM#P00389 LEPOC|Ensembl=ENSLOCG00000014736.1|UniProtKB=W5NBY4 W5NBY4 PTHR19269:SF81 TROPOMYOSIN TROPOMYOSIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000008615.1|UniProtKB=W5MQ13 W5MQ13 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG protein-containing complex binding#GO:0044877;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005353.1|UniProtKB=W5MDK9 W5MDK9 ELF1 PTHR11849:SF156 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000008565.1|UniProtKB=W5MPV7 W5MPV7 PLA2G12B PTHR12824:SF2 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIB SECRETORY PHOSPHOLIPASE A2-LIKE PROTEIN lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;triglyceride homeostasis#GO:0070328;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014703.1|UniProtKB=W5NBU2 W5NBU2 SUPT5H PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001380.1|UniProtKB=W5LZP8 W5LZP8 PTHR24103:SF672 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN_ISG15 LIGASE TRIM25 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015294.1|UniProtKB=W5NDV7 W5NDV7 PTHR19282:SF169 TETRASPANIN TETRASPANIN-6 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000153.1|UniProtKB=W5LVL4 W5LVL4 PTHR46333:SF4 CYTOKINESIS PROTEIN 3 TRANSGLUTAMINASE-LIKE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005219.1|UniProtKB=W5MD24 W5MD24 PTHR11579:SF2 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 2 transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000012530.1|UniProtKB=W5N476 W5N476 PTHR15941:SF11 MYOZENIN MYOZENIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 supramolecular complex#GO:0099080;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008362.1|UniProtKB=W5MP45 W5MP45 PTHR10996:SF257 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000627.1|UniProtKB=W5LX36 W5LX36 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013368.1|UniProtKB=W5N765 W5N765 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007799.1|UniProtKB=W5MM71 W5MM71 PTHR11905:SF112 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011924.1|UniProtKB=W5N203 W5N203 PTHR12881:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to organic substance#GO:0071310;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000003536.1|UniProtKB=W5M724 W5M724 CACFD1 PTHR13314:SF2 CALCIUM CHANNEL FLOWER HOMOLOG CALCIUM CHANNEL FLOWER HOMOLOG localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 LEPOC|Ensembl=ENSLOCG00000016131.1|UniProtKB=W5NGW7 W5NGW7 PTHR42909:SF1 ZGC:136858 CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013719.1|UniProtKB=W5N8G7 W5N8G7 PTHR11699:SF120 ALDEHYDE DEHYDROGENASE-RELATED CYTOSOLIC 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000008191.1|UniProtKB=W5MNI3 W5MNI3 PTHR46110:SF4 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011640.1|UniProtKB=W5N0Z4 W5N0Z4 PTHR16151:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000013200.1|UniProtKB=W5N6J9 W5N6J9 PTHR22999:SF40 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of monoatomic ion transport#GO:0043269;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;negative regulation of transport#GO:0051051;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;early endosome to late endosome transport#GO:0045022;negative regulation of molecular function#GO:0044092 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010598.1|UniProtKB=W5MX75 W5MX75 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002758.1|UniProtKB=W5M4E3 W5M4E3 PTHR28623:SF1 PROTEIN FAM118B PROTEIN FAM118B LEPOC|Ensembl=ENSLOCG00000000890.1|UniProtKB=W5LXY1 W5LXY1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011371.1|UniProtKB=W5N014 W5N014 DAB2 PTHR47695:SF5 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of biological process#GO:0048519;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of cell differentiation#GO:0045595;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;receptor-mediated endocytosis#GO:0006898;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;positive regulation of endocytosis#GO:0045807;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;import into cell#GO:0098657;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;clathrin-coated pit#GO:0005905;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015117.1|UniProtKB=W5ND94 W5ND94 BRS3 PTHR45695:SF6 LEUCOKININ RECEPTOR-RELATED BOMBESIN RECEPTOR SUBTYPE-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008695.1|UniProtKB=W5MQC1 W5MQC1 CRTC2 PTHR13589:SF6 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 2 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000007529.1|UniProtKB=W5ML78 W5ML78 PTHR22793:SF5 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR B transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;muscle cell differentiation#GO:0042692;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002935.1|UniProtKB=W5M501 W5M501 PTHR32035:SF3 AURORA KINASE A-INTERACTING PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN MS38 LEPOC|Ensembl=ENSLOCG00000004698.1|UniProtKB=W5MB83 W5MB83 PTHR12905:SF13 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE MPPED2 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000008468.1|UniProtKB=W5MPJ6 W5MPJ6 PTHR15110:SF2 REGULATORY FACTOR X-ASSOCIATED PROTEIN REGULATORY FACTOR X-ASSOCIATED PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016553.1|UniProtKB=W5NII3 W5NII3 PTHR16517:SF20 TUBBY-RELATED TUBBY PROTEIN HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014367.1|UniProtKB=W5NAN2 W5NAN2 PTHR12652:SF22 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11A cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;peroxisome organization#GO:0007031 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012611.1|UniProtKB=W5N4G9 W5N4G9 PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012197.1|UniProtKB=W5N302 W5N302 PTHR24381:SF453 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015242.1|UniProtKB=W5NDP6 W5NDP6 PTHR35075:SF1 A-KINASE ANCHOR PROTEIN 14 A-KINASE ANCHOR PROTEIN 14 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008914.1|UniProtKB=W5MR47 W5MR47 PTHR19248:SF16 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;iron ion binding#GO:0005506;nucleoside phosphate binding#GO:1901265;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 protein-containing complex disassembly#GO:0032984;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;translational termination#GO:0006415;peptide biosynthetic process#GO:0043043;cellular component disassembly#GO:0022411;protein-containing complex organization#GO:0043933;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000005049.1|UniProtKB=W5MCG8 W5MCG8 PTHR10605:SF62 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 6 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009128.1|UniProtKB=W5MRW6 W5MRW6 PTHR12002:SF220 CLAUDIN CLAUDIN 8-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000011276.1|UniProtKB=W5MZP6 W5MZP6 PTHR21845:SF2 TRANSMEMBRANE ANCHOR PROTEIN 1 MATRIX-REMODELING-ASSOCIATED PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000014696.1|UniProtKB=W5NBT2 W5NBT2 PTHR46002:SF6 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 2 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;positive regulation of molecular function#GO:0044093;regulation of localization#GO:0032879;positive regulation of transport#GO:0051050;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of transporter activity#GO:0032411;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014823.1|UniProtKB=W5NC92 W5NC92 PTHR11022:SF12 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 3 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016475.1|UniProtKB=W5NI93 W5NI93 PTHR46448:SF3 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN EXTRACELLULAR TYROSINE-PROTEIN KINASE PKDCC protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;skeletal system development#GO:0001501;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;peptidyl-tyrosine modification#GO:0018212;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013773.1|UniProtKB=W5N8M5 W5N8M5 PTHR45635:SF32 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 1 negative regulation of biological process#GO:0048519;membrane organization#GO:0061024;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;negative regulation of programmed cell death#GO:0043069;regulation of mitochondrion organization#GO:0010821;negative regulation of organelle organization#GO:0010639;regulation of signal transduction#GO:0009966;mitochondrion organization#GO:0007005;negative regulation of cellular component organization#GO:0051129;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;localization#GO:0051179;regulation of response to stimulus#GO:0048583;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;mitochondrial membrane organization#GO:0007006 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001420.1|UniProtKB=W5LZR7 W5LZR7 PTHR10131:SF21 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor binding#GO:0005164;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of NF-kappaB transcription factor activity#GO:0051092;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cell communication#GO:0010646;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306 LEPOC|Ensembl=ENSLOCG00000011320.1|UniProtKB=W5MZV8 W5MZV8 PTHR46021:SF3 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010594.1|UniProtKB=W5MX60 W5MX60 PTHR10250:SF26 MICROSOMAL GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012557.1|UniProtKB=W5N4A3 W5N4A3 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010059.1|UniProtKB=W5MVA5 W5MVA5 PTHR13976:SF37 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015821.1|UniProtKB=W5NFR7 W5NFR7 PTHR10151:SF125 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 5 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005532.1|UniProtKB=W5ME89 W5ME89 PTHR10407:SF10 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1-RELATED PROTEIN cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;actin binding#GO:0003779 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;cellular component biogenesis#GO:0044085;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;transport#GO:0006810;protein-containing complex assembly#GO:0065003;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;actin filament-based process#GO:0030029;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;regulation of proteolysis#GO:0030162;cellular component assembly#GO:0022607;positive regulation of catalytic activity#GO:0043085;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;actin cytoskeleton organization#GO:0030036;regulation of peptidase activity#GO:0052547;import into cell#GO:0098657;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 intracellular vesicle#GO:0097708;cortical cytoskeleton#GO:0030863;intracellular membrane-bounded organelle#GO:0043231;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-12#P00763 LEPOC|Ensembl=ENSLOCG00000000750.1|UniProtKB=W5LXI8 W5LXI8 PTHR11785:SF519 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003094.1|UniProtKB=W5M5I6 W5M5I6 PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016101.1|UniProtKB=W5NGU3 W5NGU3 USP34 PTHR24006:SF827 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008202.1|UniProtKB=W5MNK4 W5MNK4 PTHR11941:SF12 ENOYL-COA HYDRATASE-RELATED METHYLGLUTACONYL-COA HYDRATASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydratase#PC00120 LEPOC|Ensembl=ENSLOCG00000007952.1|UniProtKB=W5MMQ4 W5MMQ4 PTHR12992:SF11 NUDIX HYDROLASE MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004933.1|UniProtKB=W5MC40 W5MC40 PTHR10546:SF2 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL SUBUNIT BETA-1 protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;blood circulation#GO:0008015;regulation of sodium ion transport#GO:0002028;actin filament-based movement#GO:0030048;regulation of metal ion transport#GO:0010959;system process#GO:0003008;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016124.1|UniProtKB=W5NGV7 W5NGV7 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009178.1|UniProtKB=W5MS50 W5MS50 PTHR45622:SF18 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC3-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000180.1|UniProtKB=W5LVP4 W5LVP4 PTHR24068:SF70 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000008730.1|UniProtKB=W5MQG6 W5MQG6 PTHR48071:SF24 SRCR DOMAIN-CONTAINING PROTEIN DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-LIKE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004335.1|UniProtKB=W5M9W8 W5M9W8 PTHR44942:SF6 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN NOVEL PROTEIN LEPOC|Ensembl=ENSLOCG00000012953.1|UniProtKB=W5N5P2 W5N5P2 WHAMM PTHR23330:SF6 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES protein-containing complex binding#GO:0044877;binding#GO:0005488 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002179.1|UniProtKB=W5M2E5 W5M2E5 PTHR10628:SF23 SIALIDASE SIALIDASE-3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001153.1|UniProtKB=W5LYU3 W5LYU3 PTHR12080:SF56 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE NATURAL KILLER CELL RECEPTOR 2B4 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004996.1|UniProtKB=W5MCB4 W5MCB4 PTHR12270:SF23 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE2 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000013787.1|UniProtKB=W5N8P3 W5N8P3 PTHR23036:SF89 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 LEPOC|Ensembl=ENSLOCG00000005260.1|UniProtKB=W5MD87 W5MD87 PTHR22957:SF194 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000011102.1|UniProtKB=W5MZ42 W5MZ42 PTHR24055:SF107 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 13 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ERK#P00907;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;TGF-beta signaling pathway#P00052>P38#P01275;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>p38#P00562;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;B cell activation#P00010>p38#P00384;p38 MAPK pathway#P05918>p38delta#P06020;Oxidative stress response#P00046>p38#P01135;FGF signaling pathway#P00021>p38#P00644 LEPOC|Ensembl=ENSLOCG00000000908.1|UniProtKB=W5LY01 W5LY01 PTHR33664:SF1 RCG26366 DYNEIN AXONEMAL ASSEMBLY FACTOR 9 LEPOC|Ensembl=ENSLOCG00000005084.1|UniProtKB=W5MCN5 W5MCN5 DZIP1 PTHR21502:SF5 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000016759.1|UniProtKB=W5NJA2 W5NJA2 C8orf74 PTHR28457:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 SIMILAR TO 4930578I06RIK PROTEIN LEPOC|Ensembl=ENSLOCG00000007530.1|UniProtKB=W5ML77 W5ML77 PTHR16201:SF36 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED LYSOSOMAL AMINO ACID TRANSPORTER 1 HOMOLOG transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;basic amino acid transmembrane transporter activity#GO:0015174;organic acid transmembrane transporter activity#GO:0005342 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017933.1|UniProtKB=W5NN27 W5NN27 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005840.1|UniProtKB=W5MF90 W5MF90 PTHR46880:SF11 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN PR_SET DOMAIN 11 LEPOC|Ensembl=ENSLOCG00000010836.1|UniProtKB=W5MY23 W5MY23 PTHR11929:SF194 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 10 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004956.1|UniProtKB=W5MC63 W5MC63 PTHR44027:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016139.1|UniProtKB=W5NGX8 W5NGX8 PTHR36688:SF1 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007101.1|UniProtKB=W5MJN9 W5MJN9 PTHR47300:SF1 PROTEIN KASH5 PROTEIN KASH5 protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;meiosis I cell cycle process#GO:0061982;actin filament organization#GO:0007015;reproductive process#GO:0022414;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;spindle localization#GO:0051653;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;telomere localization#GO:0034397;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;actin cytoskeleton organization#GO:0030036;chromosome localization#GO:0050000 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;condensed chromosome#GO:0000793;organelle membrane#GO:0031090;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;nuclear membrane#GO:0031965;non-membrane-bounded organelle#GO:0043228;organelle outer membrane#GO:0031968;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;spindle#GO:0005819;envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle lumen#GO:0070013;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;outer membrane#GO:0019867;nuclear protein-containing complex#GO:0140513;synaptonemal complex#GO:0000795 LEPOC|Ensembl=ENSLOCG00000007659.1|UniProtKB=W5MLN7 W5MLN7 PTHR11216:SF64 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 2 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011650.1|UniProtKB=W5N107 W5N107 PTHR15396:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P40 RIBONUCLEASE P PROTEIN SUBUNIT P40 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;endoribonuclease complex#GO:1902555;ribonuclease MRP complex#GO:0000172;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004820.1|UniProtKB=W5MBM8 W5MBM8 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002576.1|UniProtKB=W5M3R9 W5M3R9 PTHR22923:SF3 CEREBELLIN-RELATED CEREBELLIN-4 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010372.1|UniProtKB=W5MWF7 W5MWF7 PTHR47958:SF89 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX20-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000007383.1|UniProtKB=W5MKP9 W5MKP9 PTHR24240:SF75 OPSIN VERTEBRATE ANCIENT LONG OPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003967.1|UniProtKB=W5M8N2 W5M8N2 PTHR12371:SF10 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016422.1|UniProtKB=W5NI31 W5NI31 PTHR22903:SF3 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of anatomical structure size#GO:0090066;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of biological quality#GO:0065008;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003340.1|UniProtKB=W5M6D9 W5M6D9 PTHR45915:SF7 TRANSCRIPTION INTERMEDIARY FACTOR TRIPARTITE MOTIF-CONTAINING PROTEIN 66 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010838.1|UniProtKB=W5MY25 W5MY25 PTHR36688:SF2 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013031.1|UniProtKB=W5N5Z4 W5N5Z4 PTHR21838:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017545.1|UniProtKB=W5NLZ1 W5NLZ1 PTHR16840:SF7 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC 1B LEPOC|Ensembl=ENSLOCG00000005604.1|UniProtKB=W5MEF5 W5MEF5 PTHR24014:SF4 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010441.1|UniProtKB=W5MWN8 W5MWN8 PTHR15603:SF3 SH3 DOMAIN-CONTAINING PROTEIN SH3 DOMAIN-BINDING PROTEIN 4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003996.1|UniProtKB=W5M8S0 W5M8S0 PTHR23086:SF35 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000009017.1|UniProtKB=W5MRJ1 W5MRJ1 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013539.1|UniProtKB=W5N7T8 W5N7T8 PTHR11793:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 12 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004567.1|UniProtKB=W5MAQ7 W5MAQ7 PTHR31848:SF2 FAMILY NOT NAMED REFILIN-B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;actin filament bundle organization#GO:0061572;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009736.1|UniProtKB=W5MU32 W5MU32 PTHR11834:SF7 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;embryonic organ development#GO:0048568;hippo signaling#GO:0035329;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003084.1|UniProtKB=W5M5J0 W5M5J0 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016911.1|UniProtKB=W5NJV8 W5NJV8 PTHR24058:SF53 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 2 SMAD binding#GO:0046332;protein tyrosine kinase activity#GO:0004713;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 smoothened signaling pathway#GO:0007224;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;signal transduction by p53 class mediator#GO:0072331;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;cell death#GO:0008219;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;peptidyl-threonine phosphorylation#GO:0018107;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;PML body#GO:0016605;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012836.1|UniProtKB=W5N589 W5N589 PTHR19282:SF120 TETRASPANIN TETRASPANIN-36 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010769.1|UniProtKB=W5MXU9 W5MXU9 PTHR13697:SF5 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate binding#GO:0030246;kinase activity#GO:0016301;cation binding#GO:0043169;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;monosaccharide binding#GO:0048029 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;small molecule catabolic process#GO:0044282;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;nucleoside diphosphate metabolic process#GO:0009132;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065 LEPOC|Ensembl=ENSLOCG00000014072.1|UniProtKB=W5N9N8 W5N9N8 PTHR43918:SF11 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 esterase#PC00097;hydrolase#PC00121 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 LEPOC|Ensembl=ENSLOCG00000000095.1|UniProtKB=W5LVE8 W5LVE8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000506.1|UniProtKB=W5LWP9 W5LWP9 PTHR23198:SF26 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP96 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012852.1|UniProtKB=W5N5B2 W5N5B2 PTHR11207:SF0 RIBONUCLEASE III RIBONUCLEASE 3 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;double-stranded RNA binding#GO:0003725;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015104.1|UniProtKB=W5ND79 W5ND79 PTHR22939:SF105 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA4 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015501.1|UniProtKB=W5NEL7 W5NEL7 PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013619.1|UniProtKB=W5N828 W5N828 TIMM21 PTHR13032:SF6 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000017547.1|UniProtKB=W5NLZ3 W5NLZ3 PTHR12307:SF13 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3B phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000002080.1|UniProtKB=W5M206 W5M206 PTHR21461:SF52 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017051.1|UniProtKB=W5NKB3 W5NKB3 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011701.1|UniProtKB=W5N171 W5N171 PTHR11909:SF428 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM EPSILON transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;import into cell#GO:0098657;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000010258.1|UniProtKB=W5MVZ7 W5MVZ7 PTHR12128:SF21 DIHYDRODIPICOLINATE SYNTHASE N-ACETYLNEURAMINATE LYASE lyase#PC00144 N-acetylglucosamine metabolism#P02756>N-acetylneuraminate lyase#P03040 LEPOC|Ensembl=ENSLOCG00000010408.1|UniProtKB=W5MWK5 W5MWK5 PTHR34098:SF1 F-BOX ONLY PROTEIN 47 F-BOX ONLY PROTEIN 47 LEPOC|Ensembl=ENSLOCG00000017220.1|UniProtKB=W5NKY5 W5NKY5 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002297.1|UniProtKB=W5M2V9 W5M2V9 PTHR47966:SF42 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN D hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002946.1|UniProtKB=W5M505 W5M505 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008929.1|UniProtKB=W5MR90 W5MR90 PTHR47335:SF1 UNCONVENTIONAL MYOSIN-XVI UNCONVENTIONAL MYOSIN-XVI Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000016587.1|UniProtKB=W5NIN0 W5NIN0 PTHR15758:SF2 BCL-2-LIKE PROTEIN 13 BCL-2-LIKE PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000013155.1|UniProtKB=W5N6F1 W5N6F1 PTHR11691:SF73 TYPE I INTERFERON INTERFERON BETA cytokine#PC00083;interferon superfamily#PC00127 Toll receptor signaling pathway#P00054>Gene trancription#G01550 LEPOC|Ensembl=ENSLOCG00000004902.1|UniProtKB=W5MBZ3 W5MBZ3 PTHR24027:SF319 CADHERIN-23 CADHERIN-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 cadherin#PC00057 CCKR signaling map#P06959>E-cadherin#G06981;Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Cadherin signaling pathway#P00012>Cadherin#P00471;CCKR signaling map#P06959>E-cadherin#P07171;CCKR signaling map#P06959>E-cadherin#G07274;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118 LEPOC|Ensembl=ENSLOCG00000006847.1|UniProtKB=W5MIS4 W5MIS4 PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008606.1|UniProtKB=W5MQ02 W5MQ02 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003091.1|UniProtKB=W5M5I5 W5M5I5 PTHR22603:SF68 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000017451.1|UniProtKB=W5NLP7 W5NLP7 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008150.1|UniProtKB=W5MNF4 W5MNF4 PTHR12295:SF29 FURRY-RELATED PROTEIN FURRY HOMOLOG cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007046.1|UniProtKB=W5MJH1 W5MJH1 PTHR31817:SF3 FAMILY NOT NAMED TYROSINE CARBOXYPEPTIDASE MATCAP2-RELATED LEPOC|Ensembl=ENSLOCG00000013358.1|UniProtKB=W5N757 W5N757 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>Sumo-1 ligase#P04635 LEPOC|Ensembl=ENSLOCG00000017682.1|UniProtKB=W5NMC8 W5NMC8 RXFP4 PTHR24228:SF52 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;defense response#GO:0006952;signaling#GO:0023052;inflammatory response#GO:0006954 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005074.1|UniProtKB=W5MCK5 W5MCK5 PTHR11267:SF82 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000010539.1|UniProtKB=W5MX06 W5MX06 PTHR22984:SF24 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011133.1|UniProtKB=W5MZ60 W5MZ60 PTHR12080:SF134 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000018075.1|UniProtKB=W5NNG7 W5NNG7 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016191.1|UniProtKB=W5NH48 W5NH48 PTHR15217:SF0 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mRNA modification#GO:0016556;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;RNA methylation#GO:0001510;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012918.1|UniProtKB=W5N5J7 W5N5J7 PTHR24329:SF301 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004498.1|UniProtKB=W5MAH6 W5MAH6 CFAP91 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 LEPOC|Ensembl=ENSLOCG00000005322.1|UniProtKB=W5MDF8 W5MDF8 PTHR11850:SF53 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX2 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010381.1|UniProtKB=W5MWG2 W5MWG2 PTHR24410:SF24 HL07962P-RELATED BTB DOMAIN CONTAINING 6 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010391.1|UniProtKB=W5MWH6 W5MWH6 PTHR23011:SF32 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010506.1|UniProtKB=W5MWW6 W5MWW6 PTHR15692:SF8 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 3 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;Notch signaling pathway#GO:0007219;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000003415.1|UniProtKB=W5M6Q0 W5M6Q0 PTHR11550:SF0 CTP SYNTHASE CTP SYNTHASE-RELATED identical protein binding#GO:0042802;ligase activity#GO:0016874;protein binding#GO:0005515;binding#GO:0005488;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 LEPOC|Ensembl=ENSLOCG00000015722.1|UniProtKB=W5NFE4 W5NFE4 PTHR28647:SF2 UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN chordate embryonic development#GO:0043009;system development#GO:0048731;embryo development#GO:0009790;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;skeletal system development#GO:0001501 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002240.1|UniProtKB=W5M2K1 W5M2K1 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014494.1|UniProtKB=W5NB31 W5NB31 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A INNER CENTROMERE PROTEIN A-LIKE ISOFORM X1-RELATED regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000867.1|UniProtKB=W5LXV9 W5LXV9 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC-CHELATE REDUCTASE 1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015626.1|UniProtKB=W5NF29 W5NF29 PTHR46538:SF4 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000002933.1|UniProtKB=W5M4Z1 W5M4Z1 PTHR19331:SF439 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING GROUP B PROTEIN serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015707.1|UniProtKB=W5NFE5 W5NFE5 PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;lysosomal transport#GO:0007041 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 LEPOC|Ensembl=ENSLOCG00000003125.1|UniProtKB=W5M5M5 W5M5M5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012558.1|UniProtKB=W5N4B0 W5N4B0 PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000014987.1|UniProtKB=W5NCU3 W5NCU3 PTHR24232:SF6 G-PROTEIN COUPLED RECEPTOR PURINERGIC RECEPTOR P2Y, G-PROTEIN COUPLED 10B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005461.1|UniProtKB=W5MDX5 W5MDX5 PTHR15933:SF1 PROTEIN CBG16327 F-BOX ONLY PROTEIN 40 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007602.1|UniProtKB=W5MLG3 W5MLG3 PTHR24168:SF0 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cellular component organization#GO:0051129;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cell communication#GO:0010648;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;regulation of cell cycle phase transition#GO:1901987;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;negative regulation of signal transduction#GO:0009968;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cytoskeleton organization#GO:0051494;regulation of metabolic process#GO:0019222;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of protein polymerization#GO:0032272;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;negative regulation of cell cycle process#GO:0010948;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of protein-containing complex assembly#GO:0043254;regulation of biosynthetic process#GO:0009889;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of cell population proliferation#GO:0008285;regulation of actin filament-based process#GO:0032970;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of protein polymerization#GO:0032271;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;regulation of response to external stimulus#GO:0032101;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of cell population proliferation#GO:0042127;regulation of actin filament length#GO:0030832;regulation of DNA-templated transcription#GO:0006355;negative regulation of cell cycle phase transition#GO:1901988;regulation of actin filament organization#GO:0110053;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of primary metabolic process#GO:0080090;regulation of supramolecular fiber organization#GO:1902903;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008736.1|UniProtKB=W5MQH2 W5MQH2 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003969.1|UniProtKB=W5M8P9 W5M8P9 PTHR22599:SF12 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3C protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000008788.1|UniProtKB=W5MQN8 W5MQN8 PTHR10165:SF79 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;cellular metabolic process#GO:0044237;cell adhesion#GO:0007155;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000947.1|UniProtKB=W5LY53 W5LY53 PTHR24388:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 341 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009035.1|UniProtKB=W5MRK6 W5MRK6 MTSS1 PTHR15708:SF10 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;positive regulation of organelle organization#GO:0010638;membrane organization#GO:0061024;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;positive regulation of actin filament bundle assembly#GO:0032233;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of actin filament bundle assembly#GO:0032231;adherens junction organization#GO:0034332 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005087.1|UniProtKB=W5MCM0 W5MCM0 MOCOS PTHR14237:SF80 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MOLYBDENUM COFACTOR SULFURASE LEPOC|Ensembl=ENSLOCG00000012787.1|UniProtKB=W5N524 W5N524 PTHR13968:SF21 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING RALY-LIKE PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015579.1|UniProtKB=W5NEX4 W5NEX4 PTHR10217:SF530 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013973.1|UniProtKB=W5N9B5 W5N9B5 PTHR28593:SF1 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010100.1|UniProtKB=W5MVF2 W5MVF2 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010495.1|UniProtKB=W5MWV8 W5MWV8 PTHR21614:SF4 SHORT COILED COIL PROTEIN SHORT COILED-COIL PROTEIN A cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003224.1|UniProtKB=W5M606 W5M606 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016145.1|UniProtKB=W5NGZ1 W5NGZ1 PTHR11141:SF10 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23B nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015160.1|UniProtKB=W5NDE9 W5NDE9 PTHR16078:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 LEPOC|Ensembl=ENSLOCG00000014144.1|UniProtKB=W5N9W5 W5N9W5 PTHR24377:SF929 IP01015P-RELATED ZINC FINGER PROTEIN 665 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008341.1|UniProtKB=W5MP23 W5MP23 PTHR24012:SF719 RNA BINDING PROTEIN RNA BINDING MOTIF PROTEIN 19 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010266.1|UniProtKB=W5MW20 W5MW20 PTHR11743:SF13 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1 voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016061.1|UniProtKB=W5NGN3 W5NGN3 PTHR24026:SF36 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 1 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000015588.1|UniProtKB=W5NEY8 W5NEY8 PTHR43272:SF36 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018247.1|UniProtKB=W5NNY9 W5NNY9 PTHR22752:SF11 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 62 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;receptor complex#GO:0043235;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003056.1|UniProtKB=W5M5D4 W5M5D4 PTHR46970:SF1 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 LEPOC|Ensembl=ENSLOCG00000006799.1|UniProtKB=W5MIK7 W5MIK7 PTHR12622:SF42 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016405.1|UniProtKB=W5NI08 W5NI08 PTHR48041:SF71 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8 cholesterol transfer activity#GO:0120020;transmembrane transporter activity#GO:0022857;sterol transfer activity#GO:0120015;primary active transmembrane transporter activity#GO:0015399;lipid transfer activity#GO:0120013;ATP-dependent activity#GO:0140657;sterol transporter activity#GO:0015248;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cholesterol homeostasis#GO:0042632;lipid transport#GO:0006869;localization#GO:0051179;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;lipid localization#GO:0010876;cholesterol efflux#GO:0033344 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005958.1|UniProtKB=W5MFN4 W5MFN4 PTHR12413:SF2 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015254.1|UniProtKB=W5NDR1 W5NDR1 PTHR16209:SF7 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN 1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000007540.1|UniProtKB=W5MLB6 W5MLB6 PTHR24255:SF25 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1R SUBCOMPONENT hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007170.1|UniProtKB=W5MJW7 W5MJW7 PTHR11952:SF4 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000016146.1|UniProtKB=W5NGY6 W5NGY6 SLC15A5 PTHR11654:SF91 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013156.1|UniProtKB=W5N6E9 W5N6E9 PTHR16277:SF16 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000017514.1|UniProtKB=W5NLW0 W5NLW0 PTHR31463:SF5 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000015386.1|UniProtKB=W5NE78 W5NE78 PTHR15715:SF17 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002651.1|UniProtKB=W5M405 W5M405 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L LEPOC|Ensembl=ENSLOCG00000009911.1|UniProtKB=W5MUR3 W5MUR3 ATP4B PTHR11523:SF11 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009392.1|UniProtKB=W5MSU2 W5MSU2 PTHR11829:SF383 FORKHEAD BOX PROTEIN FORKHEAD BOX I2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000007027.1|UniProtKB=W5MJE7 W5MJE7 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003509.1|UniProtKB=W5M705 W5M705 PTHR10127:SF860 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;dorsal/ventral pattern formation#GO:0009953;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;proteolysis#GO:0006508;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000013686.1|UniProtKB=W5N8B9 W5N8B9 PTHR12692:SF2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED MAGNESIUM TRANSPORTER PROTEIN 1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010026.1|UniProtKB=W5MV59 W5MV59 PTHR45752:SF58 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016848.1|UniProtKB=W5NJL8 W5NJL8 PTHR47977:SF104 RAS-RELATED PROTEIN RAB CALCIUM RELEASE-ACTIVATED CHANNEL REGULATOR 2AB-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000009865.1|UniProtKB=W5MUK3 W5MUK3 PTHR15427:SF24 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018079.1|UniProtKB=W5NNH1 W5NNH1 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007991.1|UniProtKB=W5MMU6 W5MMU6 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014189.1|UniProtKB=W5NA23 W5NA23 PTHR43782:SF4 ARGINASE ARGINASE-2, MITOCHONDRIAL cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;arginine metabolic process#GO:0006525;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017903.1|UniProtKB=W5NMZ7 W5NMZ7 PTHR12151:SF2 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER PROTEIN SCO2 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015073.1|UniProtKB=W5ND44 W5ND44 PTHR10182:SF18 CALCIUM-BINDING PROTEIN 39-RELATED CAB39 PROTEIN protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000015490.1|UniProtKB=W5NEK6 W5NEK6 PTHR15976:SF17 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013718.1|UniProtKB=W5N8F5 W5N8F5 PTHR35345:SF1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;telomere localization#GO:0034397;reproduction#GO:0000003;chromosome organization#GO:0051276;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;cell cycle#GO:0007049;chromosome localization#GO:0050000 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012590.1|UniProtKB=W5N4F0 W5N4F0 PTHR11153:SF20 SIDEROFLEXIN SIDEROFLEXIN-3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001441.1|UniProtKB=W5LZV4 W5LZV4 PTHR24023:SF1100 COLLAGEN ALPHA FIBRILLAR COLLAGEN NC1 DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003798.1|UniProtKB=W5M835 W5M835 PTHR12656:SF12 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1A nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000005497.1|UniProtKB=W5ME24 W5ME24 ROPN1 PTHR14952:SF12 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1B sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;spermatid differentiation#GO:0048515;cellular process#GO:0009987;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 cytoplasm#GO:0005737;motile cilium#GO:0031514;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016081.1|UniProtKB=W5NGQ9 W5NGQ9 CPNE8 PTHR10857:SF133 COPINE COPINE-8 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000012822.1|UniProtKB=W5N566 W5N566 PTHR24346:SF30 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000780.1|UniProtKB=W5LXL0 W5LXL0 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004564.1|UniProtKB=W5MAQ4 W5MAQ4 PTHR24232:SF101 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 35-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016510.1|UniProtKB=W5NID4 W5NID4 PTHR10796:SF15 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017462.1|UniProtKB=W5NLQ8 W5NLQ8 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007257.1|UniProtKB=W5MK72 W5MK72 PTHR45781:SF3 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000013125.1|UniProtKB=W5N6A7 W5N6A7 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000012126.1|UniProtKB=W5N2R8 W5N2R8 PTHR42737:SF2 GLUTATHIONE REDUCTASE GLUTATHIONE REDUCTASE nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;disulfide oxidoreductase activity#GO:0015036;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009758.1|UniProtKB=W5MU64 W5MU64 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;positive regulation of protein modification process#GO:0031401;translation#GO:0006412;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;translational elongation#GO:0006414;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001333.1|UniProtKB=W5LZG5 W5LZG5 PTHR36754:SF2 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;aminoacyltransferase activity#GO:0016755;ubiquitin protein ligase binding#GO:0031625;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;transferase activity#GO:0016740;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor binding#GO:0005164;cytokine receptor binding#GO:0005126 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006296.1|UniProtKB=W5MGW6 W5MGW6 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004298.1|UniProtKB=W5M9S6 W5M9S6 PTHR11081:SF49 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 HOMOLOG-RELATED hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;magnesium ion binding#GO:0000287;5'-3' exonuclease activity#GO:0008409;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;metal ion binding#GO:0046872;exonuclease activity#GO:0004527;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;cation binding#GO:0043169;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;ion binding#GO:0043167;RNA nuclease activity#GO:0004540 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000017184.1|UniProtKB=W5NKT0 W5NKT0 PTHR47130:SF3 SI:DKEY-19B23.11-RELATED ZONA PELLUCIDA PROTEIN LEPOC|Ensembl=ENSLOCG00000002089.1|UniProtKB=W5M234 W5M234 PTHR11328:SF29 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;phospholipid transporter activity#GO:0005548;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 monocarboxylic acid transport#GO:0015718;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;system process#GO:0003008;carboxylic acid transport#GO:0046942;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;circulatory system process#GO:0003013;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;multicellular organismal process#GO:0032501;lipid localization#GO:0010876;carbohydrate derivative transport#GO:1901264;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012892.1|UniProtKB=W5N5G3 W5N5G3 PTHR24257:SF10 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER ELASTASE-1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015372.1|UniProtKB=W5NE57 W5NE57 SHISAL1 PTHR31395:SF11 SHISA PROTEIN SHISA-LIKE-1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015536.1|UniProtKB=W5NER4 W5NER4 PTHR10026:SF70 CYCLIN CYCLIN-Q protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000003088.1|UniProtKB=W5M5I8 W5M5I8 PTHR23319:SF1 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-C cholesterol transfer activity#GO:0120020;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;cholesterol binding#GO:0015485 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;intracellular sterol transport#GO:0032366;establishment of localization in cell#GO:0051649;lipid localization#GO:0010876;intracellular transport#GO:0046907;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular lipid transport#GO:0032365 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014248.1|UniProtKB=W5NAB3 W5NAB3 PTHR46399:SF10 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 negative regulation of biological process#GO:0048519;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;regulation of sequestering of calcium ion#GO:0051282;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;release of sequestered calcium ion into cytosol#GO:0051209;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;striated muscle contraction#GO:0006941;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655;negative regulation of cellular process#GO:0048523;muscle system process#GO:0003012;muscle contraction#GO:0006936 bounding membrane of organelle#GO:0098588;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;sarcomere#GO:0030017;transmembrane transporter complex#GO:1902495;myofibril#GO:0030016;membrane protein complex#GO:0098796;sarcoplasmic reticulum#GO:0016529;Z disc#GO:0030018;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;contractile fiber#GO:0043292;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 LEPOC|Ensembl=ENSLOCG00000013466.1|UniProtKB=W5N7J9 W5N7J9 PTHR13475:SF5 NEUGRIN NEUGRIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001131.1|UniProtKB=W5LYS2 W5LYS2 FCN1 PTHR19143:SF433 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;complement activation#GO:0006956 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015262.1|UniProtKB=W5NDS2 W5NDS2 PTHR12425:SF2 SYNEMBRYN SYNEMBRYN-B nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;binding#GO:0005488;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017803.1|UniProtKB=W5NMP8 W5NMP8 PRSS23 PTHR15462:SF10 SERINE PROTEASE SERINE PROTEASE 23 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000001226.1|UniProtKB=W5LZ32 W5LZ32 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007445.1|UniProtKB=W5MKX1 W5MKX1 PTHR20996:SF1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;protein serine/threonine phosphatase complex#GO:0008287;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000017746.1|UniProtKB=W5NMJ1 W5NMJ1 PTHR15895:SF12 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5 PROTEIN LEPOC|Ensembl=ENSLOCG00000015513.1|UniProtKB=W5NEN3 W5NEN3 PTHR12019:SF5 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN EMERIN (EMERY-DREIFUSS MUSCULAR DYSTROPHY) peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000002380.1|UniProtKB=W5M337 W5M337 PTHR12461:SF43 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HSPB1-ASSOCIATED PROTEIN 1 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001239.1|UniProtKB=W5LZ44 W5LZ44 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006877.1|UniProtKB=W5MIV7 W5MIV7 PTHR46861:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A signaling receptor activity#GO:0038023;death receptor activity#GO:0005035;binding#GO:0005488;cytokine binding#GO:0019955;protein binding#GO:0005515;molecular transducer activity#GO:0060089;tumor necrosis factor binding#GO:0043120;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to stress#GO:0006950;defense response#GO:0006952;inflammatory response#GO:0006954 receptor complex#GO:0043235;membrane raft#GO:0045121;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane microdomain#GO:0098857 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TNFR1#P00288 LEPOC|Ensembl=ENSLOCG00000006960.1|UniProtKB=W5MJ55 W5MJ55 PTHR11712:SF336 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000011325.1|UniProtKB=W5MZW3 W5MZW3 NFIB PTHR11492:SF4 NUCLEAR FACTOR I NUCLEAR FACTOR 1 B-TYPE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004011.1|UniProtKB=W5M8T4 W5M8T4 PTHR11551:SF27 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 6A PRECURSOR-RELATED growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015716.1|UniProtKB=W5NFD6 W5NFD6 PTHR24347:SF252 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005661.1|UniProtKB=W5MEM3 W5MEM3 PTHR22930:SF253 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED LEPOC|Ensembl=ENSLOCG00000004050.1|UniProtKB=W5M8Z7 W5M8Z7 PTHR12371:SF3 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1 protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014028.1|UniProtKB=W5N9I1 W5N9I1 PTHR14198:SF23 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED SI:CH211-137I24.10 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014974.1|UniProtKB=W5NCT1 W5NCT1 PTHR16059:SF11 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001661.1|UniProtKB=W5M0L3 W5M0L3 PTHR24347:SF371 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010513.1|UniProtKB=W5MWZ2 W5MWZ2 PTHR19961:SF35 FIMBRIN/PLASTIN PLASTIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004689.1|UniProtKB=W5MB57 W5MB57 PTHR11422:SF3 T-CELL SURFACE GLYCOPROTEIN CD4 G6F-LIKE PROTEIN binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;MHC protein binding#GO:0042287;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;lymphocyte activation#GO:0046649;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001087.1|UniProtKB=W5LYL8 W5LYL8 PTHR14949:SF52 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 anatomical structure development#GO:0048856;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001304.1|UniProtKB=W5LZC7 W5LZC7 PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011105.1|UniProtKB=W5MZ34 W5MZ34 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001894.1|UniProtKB=W5M1D8 W5M1D8 PTHR46661:SF3 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008390.1|UniProtKB=W5MP84 W5MP84 PTHR12612:SF25 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000413.1|UniProtKB=W5LWE7 W5LWE7 PTHR23235:SF50 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014942.1|UniProtKB=W5NCN7 W5NCN7 PTHR45877:SF4 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>SIAH-1#P01433 LEPOC|Ensembl=ENSLOCG00000006092.1|UniProtKB=W5MG80 W5MG80 PTHR46459:SF1 E1A-BINDING PROTEIN P400-RELATED E1A-BINDING PROTEIN P400 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000014301.1|UniProtKB=W5NAF1 W5NAF1 PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;contractile actin filament bundle assembly#GO:0030038;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;stress fiber assembly#GO:0043149;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;Rho protein signal transduction#GO:0007266;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cytosol#GO:0005829;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell division site#GO:0032153;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;CCKR signaling map#P06959>RHOA-GTP#P07188;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GDP#P07019;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254 LEPOC|Ensembl=ENSLOCG00000002769.1|UniProtKB=W5M4F6 W5M4F6 PTHR24404:SF53 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 148 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007484.1|UniProtKB=W5ML39 W5ML39 PTHR11801:SF41 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to biotic stimulus#GO:0009607;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;defense response#GO:0006952;signaling#GO:0023052;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;defense response to symbiont#GO:0140546;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to hormone#GO:0009725;response to stress#GO:0006950;receptor signaling pathway via STAT#GO:0097696;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;type I interferon-mediated signaling pathway#GO:0060337;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 LEPOC|Ensembl=ENSLOCG00000010116.1|UniProtKB=W5MVH1 W5MVH1 PTHR22846:SF52 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1X molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Ebi#P01453 LEPOC|Ensembl=ENSLOCG00000003377.1|UniProtKB=W5M6J6 W5M6J6 PTHR14594:SF1 CENTROSOMAL PROTEIN OF 70 KDA CENTROSOMAL PROTEIN OF 70 KDA organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017730.1|UniProtKB=W5NMH5 W5NMH5 PTHR13627:SF31 FUKUTIN RELATED PROTEIN RIBITOL 5-PHOSPHATE TRANSFERASE FKRP LEPOC|Ensembl=ENSLOCG00000014959.1|UniProtKB=W5NCR1 W5NCR1 PTHR23336:SF22 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 4 protein binding#GO:0005515;methylated histone binding#GO:0035064;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013819.1|UniProtKB=W5N8T0 W5N8T0 YBX2 PTHR11544:SF61 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000005783.1|UniProtKB=W5MF26 W5MF26 PTHR10408:SF10 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;sterol binding#GO:0032934;O-acyltransferase activity#GO:0008374;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;lipid transport#GO:0006869;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;cholesterol transport#GO:0030301;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;cholesterol efflux#GO:0033344;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000002720.1|UniProtKB=W5M4B3 W5M4B3 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000565.1|UniProtKB=W5LWW6 W5LWW6 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011254.1|UniProtKB=W5MZL8 W5MZL8 SLC22A15 PTHR24064:SF170 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 15 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009712.1|UniProtKB=W5MU03 W5MU03 PTHR45805:SF6 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017588.1|UniProtKB=W5NM34 W5NM34 PTHR11786:SF8 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000015717.1|UniProtKB=W5NFD8 W5NFD8 CCDC3 PTHR31663:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003401.1|UniProtKB=W5M6M2 W5M6M2 PTHR10605:SF45 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018018.1|UniProtKB=W5NNB0 W5NNB0 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017799.1|UniProtKB=W5NMP4 W5NMP4 PTHR10270:SF328 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;head development#GO:0060322;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000006742.1|UniProtKB=W5MID5 W5MID5 PTHR17614:SF13 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002753.1|UniProtKB=W5M4D7 W5M4D7 PTHR21541:SF3 BTB POZ DOMAIN CONTAINING 12 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000000168.1|UniProtKB=W5LVN0 W5LVN0 PTHR45598:SF1 PROTEIN CBG11839-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002015.1|UniProtKB=W5M1S9 W5M1S9 PTHR31367:SF2 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;adenosine metabolic process#GO:0046085;purine-containing compound metabolic process#GO:0072521;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005304.1|UniProtKB=W5MDD6 W5MDD6 PTHR23055:SF168 CALCIUM BINDING PROTEINS GUANYLATE CYCLASE ACTIVATING PROTEIN 7 cation binding#GO:0043169;molecular function activator activity#GO:0140677;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;enzyme activator activity#GO:0008047;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 regulation of lyase activity#GO:0051339;regulation of phosphate metabolic process#GO:0019220;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cyclase activity#GO:0031279;system process#GO:0003008;nervous system process#GO:0050877;visual perception#GO:0007601;regulation of catalytic activity#GO:0050790;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;photoreceptor inner segment#GO:0001917;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000015346.1|UniProtKB=W5NE26 W5NE26 PTHR24028:SF40 CADHERIN-87A PROTOCADHERIN-19 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000017071.1|UniProtKB=W5NKD7 W5NKD7 PTHR14042:SF22 DOPEY-RELATED PROTEIN DOPEY-1 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000001785.1|UniProtKB=W5M112 W5M112 PTHR32073:SF8 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2B LEPOC|Ensembl=ENSLOCG00000016749.1|UniProtKB=W5NJ94 W5NJ94 PTHR45972:SF2 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH-LIKE PROTEIN 42 regulation of microtubule-based process#GO:0032886;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006502.1|UniProtKB=W5MHK2 W5MHK2 PTHR45805:SF7 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000659.1|UniProtKB=W5LXC7 W5LXC7 ATP11B PTHR24092:SF57 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IF ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001512.1|UniProtKB=W5M023 W5M023 PTHR43788:SF8 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001521.1|UniProtKB=W5M032 W5M032 PTHR13170:SF23 O-GLCNACASE PROTEIN O-GLCNACASE-LIKE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007565.1|UniProtKB=W5MLC1 W5MLC1 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009669.1|UniProtKB=W5MTV2 W5MTV2 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017732.1|UniProtKB=W5NMH7 W5NMH7 PTHR24365:SF17 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000009938.1|UniProtKB=W5MUU8 W5MUU8 PTHR10137:SF5 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015395.1|UniProtKB=W5NE84 W5NE84 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004220.1|UniProtKB=W5M9I7 W5M9I7 PTHR19964:SF33 MULTIPLE PDZ DOMAIN PROTEIN LIGAND OF NUMB PROTEIN X 2 aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 LEPOC|Ensembl=ENSLOCG00000012393.1|UniProtKB=W5N3Q8 W5N3Q8 EZH1 PTHR45747:SF20 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) [HISTONE H3]-LYSINE(27) N-TRIMETHYLTRANSFERASE N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;protein-containing complex binding#GO:0044877;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007731.1|UniProtKB=W5MLX8 W5MLX8 PTHR22142:SF2 FAMILY NOT NAMED KINETOCHORE PROTEIN SPC24 LEPOC|Ensembl=ENSLOCG00000013303.1|UniProtKB=W5N6Y6 W5N6Y6 HUS1 PTHR12900:SF0 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;telomere organization#GO:0032200;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;negative regulation of mitotic cell cycle phase transition#GO:1901991;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;mitotic DNA replication checkpoint signaling#GO:0033314;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;DNA replication checkpoint signaling#GO:0000076;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016093.1|UniProtKB=W5NGR8 W5NGR8 PTHR47970:SF12 KINESIN-LIKE PROTEIN KIF11 KINESIN FAMILY MEMBER 11 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;plus-end-directed microtubule motor activity#GO:0008574;ATP-dependent activity#GO:0140657 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;spindle elongation#GO:0051231;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003376.1|UniProtKB=W5M6K5 W5M6K5 PTHR23192:SF68 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005099.1|UniProtKB=W5MCP0 W5MCP0 PTHR11049:SF24 ACYL COENZYME A THIOESTER HYDROLASE CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;lipid catabolic process#GO:0016042;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000016374.1|UniProtKB=W5NHV8 W5NHV8 PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004232.1|UniProtKB=W5M9J8 W5M9J8 ARTN PTHR12173:SF8 GDNF SUBFAMILY OF TGF-BETA FAMILY PERSEPHIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neurotrophic factor#PC00163;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000016890.1|UniProtKB=W5NJS1 W5NJS1 PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000010607.1|UniProtKB=W5MX84 W5MX84 PTHR16007:SF21 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45A LEPOC|Ensembl=ENSLOCG00000004807.1|UniProtKB=W5MBK8 W5MBK8 PTHR28375:SF1 PROTEIN HINDERIN PROTEIN HINDERIN LEPOC|Ensembl=ENSLOCG00000017783.1|UniProtKB=W5NMM8 W5NMM8 PTHR10270:SF313 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-21 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;head development#GO:0060322;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000004206.1|UniProtKB=W5M9H1 W5M9H1 PTHR45891:SF4 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of neuron differentiation#GO:0045664;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000985.1|UniProtKB=W5LYA1 W5LYA1 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009416.1|UniProtKB=W5MSY0 W5MSY0 PTHR43139:SF52 SI:DKEY-122A22.2 SI:DKEY-122A22.2 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009474.1|UniProtKB=W5MT99 W5MT99 PTHR13817:SF69 TITIN ROUNDABOUT GUIDANCE RECEPTOR 2 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007104.1|UniProtKB=W5MJP6 W5MJP6 PTHR15492:SF1 CYCLIN D1-BINDING PROTEIN 1 CYCLIN-D1-BINDING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007704.1|UniProtKB=W5MLU9 W5MLU9 PTHR12112:SF21 BNIP - RELATED BCL-2_ADENOVIRUS E1B 19 KDA-INTERACTING PROTEIN 2-LIKE PROTEIN cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010599.1|UniProtKB=W5MX77 W5MX77 IFT43 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;plasma membrane bounded cell projection organization#GO:0120036;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000012036.1|UniProtKB=W5N2F0 W5N2F0 PTHR46900:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015565.1|UniProtKB=W5NEV3 W5NEV3 PTHR48071:SF26 SRCR DOMAIN-CONTAINING PROTEIN ANTIGEN WC1.1-LIKE LEPOC|Ensembl=ENSLOCG00000014271.1|UniProtKB=W5NAA9 W5NAA9 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012173.1|UniProtKB=W5N2X3 W5N2X3 PTHR24027:SF323 CADHERIN-23 CADHERIN-19 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000007527.1|UniProtKB=W5ML89 W5ML89 RS1 PTHR24543:SF295 MULTICOPPER OXIDASE-RELATED RETINOSCHISIN oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001607.1|UniProtKB=W5M0E7 W5M0E7 PTHR19134:SF553 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE 10D-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Axon guidance mediated by Slit/Robo#P00008>Ptp10D#P00343 LEPOC|Ensembl=ENSLOCG00000006454.1|UniProtKB=W5MHD6 W5MHD6 PTHR48112:SF36 HIGH MOBILITY GROUP PROTEIN DSP1 TRANSCRIPTION FACTOR A, MITOCHONDRIAL regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000006840.1|UniProtKB=W5MIR1 W5MIR1 PTHR15571:SF2 GEM-ASSOCIATED PROTEIN 4 GEM-ASSOCIATED PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000012933.1|UniProtKB=W5N5M3 W5N5M3 PTHR24214:SF32 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 5 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013602.1|UniProtKB=W5N811 W5N811 PTHR28632:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000012308.1|UniProtKB=W5N3F9 W5N3F9 PTHR22754:SF33 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG C LEPOC|Ensembl=ENSLOCG00000004719.1|UniProtKB=W5MB95 W5MB95 FAM76A PTHR46176:SF2 LD21662P PROTEIN FAM76A membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014239.1|UniProtKB=W5NA75 W5NA75 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR COMPLEX PROTEIN NPRL2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;regulation of cellular catabolic process#GO:0031329;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;negative regulation of TORC1 signaling#GO:1904262;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000010056.1|UniProtKB=W5MV95 W5MV95 EVC PTHR16795:SF13 LIMBIN/ELLIS-VAN CREVELD PROTEIN EVC COMPLEX MEMBER EVC bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ciliary membrane#GO:0060170;plasma membrane protein complex#GO:0098797;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013065.1|UniProtKB=W5N638 W5N638 TNS3 PTHR45734:SF5 TENSIN TENSIN-3 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004412.1|UniProtKB=W5MA81 W5MA81 PTHR24248:SF87 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(2) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;regulation of metal ion transport#GO:0010959;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;negative regulation of lyase activity#GO:0051350;negative regulation of cell communication#GO:0010648;regulation of monoatomic ion transmembrane transport#GO:0034765;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;response to nitrogen compound#GO:1901698;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;negative regulation of monoatomic ion transport#GO:0043271;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;negative regulation of cyclase activity#GO:0031280;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of adenylate cyclase activity#GO:0007194;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 presynapse#GO:0098793;synapse#GO:0045202;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Gonadotropin-releasing hormone receptor pathway#P06664>DRD2#P06758 LEPOC|Ensembl=ENSLOCG00000005620.1|UniProtKB=W5MEH7 W5MEH7 AMHR2 PTHR23255:SF49 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ANTI-MUELLERIAN HORMONE TYPE-2 RECEPTOR signaling receptor activity#GO:0038023;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>MISRII#P06792;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 LEPOC|Ensembl=ENSLOCG00000013470.1|UniProtKB=W5N7K8 W5N7K8 PTHR10693:SF10 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006311.1|UniProtKB=W5MGW5 W5MGW5 PTHR22619:SF4 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 4 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000002214.1|UniProtKB=W5M2G8 W5M2G8 PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000018191.1|UniProtKB=W5NNT3 W5NNT3 SMCO3 PTHR35972:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000004095.1|UniProtKB=W5M941 W5M941 PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE MINOR HISTOCOMPATIBILITY ANTIGEN H13 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;signal peptide processing#GO:0006465;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;side of membrane#GO:0098552;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011829.1|UniProtKB=W5N1P3 W5N1P3 PTHR10217:SF638 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL ERG K+ CHANNEL monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of heart contraction#GO:0008016;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;regulation of system process#GO:0044057;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009954.1|UniProtKB=W5MUW9 W5MUW9 PTHR12544:SF49 GLUTAMINASE GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 dicarboxylic acid metabolic process#GO:0043648;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009034.1|UniProtKB=W5MRK4 W5MRK4 PTHR12300:SF93 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 5 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013341.1|UniProtKB=W5N734 W5N734 PTHR47368:SF5 NUMB PROTEIN NUMB HOMOLOG regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;basal plasma membrane#GO:0009925;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;basal part of cell#GO:0045178;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Numb#P01118 LEPOC|Ensembl=ENSLOCG00000016710.1|UniProtKB=W5NJ36 W5NJ36 PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000007575.1|UniProtKB=W5MLE4 W5MLE4 PTHR11347:SF74 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000003042.1|UniProtKB=W5M5C0 W5M5C0 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000017147.1|UniProtKB=W5NKN2 W5NKN2 PTHR45617:SF166 LEUCINE RICH REPEAT FAMILY PROTEIN PODOCAN-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013319.1|UniProtKB=W5N710 W5N710 PTHR18929:SF210 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A4 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cell surface#GO:0009986;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013890.1|UniProtKB=W5N924 W5N924 PTHR24093:SF377 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014988.1|UniProtKB=W5NCU5 W5NCU5 PTHR46973:SF1 GRAM DOMAIN-CONTAINING PROTEIN 2A GRAM DOMAIN-CONTAINING PROTEIN 2A phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000008683.1|UniProtKB=W5MQB8 W5MQB8 PTHR12203:SF21 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000007283.1|UniProtKB=W5MKB2 W5MKB2 PTHR23233:SF51 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016119.1|UniProtKB=W5NGV4 W5NGV4 SANBR PTHR20946:SF0 SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION LEPOC|Ensembl=ENSLOCG00000013249.1|UniProtKB=W5N6R7 W5N6R7 PTHR46212:SF9 PEFLIN PROGRAMMED CELL DEATH PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000006734.1|UniProtKB=W5MIE1 W5MIE1 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000014470.1|UniProtKB=W5NB01 W5NB01 PTHR12606:SF16 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 3 hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017024.1|UniProtKB=W5NK82 W5NK82 PTHR10157:SF42 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 1 HOMOLOG cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 organic hydroxy compound metabolic process#GO:1901615;cellular aromatic compound metabolic process#GO:0006725;amine metabolic process#GO:0009308;alcohol biosynthetic process#GO:0046165;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;catecholamine metabolic process#GO:0006584;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;extracellular region#GO:0005576;secretory granule#GO:0030141;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000002860.1|UniProtKB=W5M4Q8 W5M4Q8 PTHR23288:SF6 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000017940.1|UniProtKB=W5NN34 W5NN34 PTHR23189:SF43 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012589.1|UniProtKB=W5N4E7 W5N4E7 PTHR23067:SF6 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385C membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005538.1|UniProtKB=W5ME76 W5ME76 PTHR48092:SF6 KNIRPS-RELATED PROTEIN-RELATED PROGESTERONE RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>PR#P06708 LEPOC|Ensembl=ENSLOCG00000007596.1|UniProtKB=W5MLF5 W5MLF5 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002778.1|UniProtKB=W5M4G1 W5M4G1 PTHR10760:SF4 TORSIN TORSIN-2A envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 LEPOC|Ensembl=ENSLOCG00000014544.1|UniProtKB=W5NB98 W5NB98 PTHR24034:SF194 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000005603.1|UniProtKB=W5MEF1 W5MEF1 PTHR23430:SF28 HISTONE H2A HISTONE H2A TYPE 1-C nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006297.1|UniProtKB=W5MGX4 W5MGX4 PTHR10283:SF109 SOLUTE CARRIER FAMILY 13 MEMBER NA(+)_CITRATE COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;citrate transmembrane transporter activity#GO:0015137;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic substance transport#GO:0071702;succinate transport#GO:0015744;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006727.1|UniProtKB=W5MIB9 W5MIB9 PTHR45762:SF21 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011009.1|UniProtKB=W5MYQ0 W5MYQ0 PTHR43766:SF1 TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008249.1|UniProtKB=W5MNR2 W5MNR2 PTHR24115:SF458 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007787.1|UniProtKB=W5MM40 W5MM40 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT EPSILON antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000018304.1|UniProtKB=W5NP46 W5NP46 PTHR31894:SF0 UPF0461 PROTEIN C5ORF24 UPF0461 PROTEIN C5ORF24 LEPOC|Ensembl=ENSLOCG00000008046.1|UniProtKB=W5MN13 W5MN13 PTHR15853:SF0 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004611.1|UniProtKB=W5MAW3 W5MAW3 TCF24 PTHR23349:SF48 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 24 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000005530.1|UniProtKB=W5ME67 W5ME67 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 peptidase activator activity#GO:0016504;proteasome binding#GO:0070628;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;protein-containing complex binding#GO:0044877;endopeptidase regulator activity#GO:0061135;enzyme regulator activity#GO:0030234 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012328.1|UniProtKB=W5N3G7 W5N3G7 PTHR21682:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 LEPOC|Ensembl=ENSLOCG00000006674.1|UniProtKB=W5MI49 W5MI49 APH1A PTHR12889:SF1 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;Notch signaling pathway#GO:0007219 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091 LEPOC|Ensembl=ENSLOCG00000017472.1|UniProtKB=W5NLR8 W5NLR8 PTHR22750:SF25 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 12-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013251.1|UniProtKB=W5N6S5 W5N6S5 PTHR15715:SF22 CENTROSOMAL PROTEIN OF 170 KDA SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN protein localization to plasma membrane#GO:0072659;regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of monoatomic ion transmembrane transport#GO:0034765;localization within membrane#GO:0051668;regulation of transmembrane transport#GO:0034762;cellular localization#GO:0051641;regulation of sodium ion transport#GO:0002028;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;regulation of metal ion transport#GO:0010959;regulation of membrane potential#GO:0042391;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;protein localization to cell periphery#GO:1990778;regulation of transport#GO:0051049;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;regulation of membrane depolarization#GO:0003254 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001126.1|UniProtKB=W5LYT1 W5LYT1 PTHR12027:SF105 WNT RELATED PROTEIN WNT-4A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000012520.1|UniProtKB=W5N468 W5N468 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000016755.1|UniProtKB=W5NJ98 W5NJ98 PTHR24418:SF181 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BLK protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;B cell activation#P00010>Blk#P00390 LEPOC|Ensembl=ENSLOCG00000015867.1|UniProtKB=W5NFY3 W5NFY3 PTHR13280:SF14 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 LEPOC|Ensembl=ENSLOCG00000015222.1|UniProtKB=W5NDM3 W5NDM3 PTHR13005:SF2 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016223.1|UniProtKB=W5NHA7 W5NHA7 MAP3K4 PTHR24348:SF64 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE DDB_G0278901-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016885.1|UniProtKB=W5NJR4 W5NJR4 ELOVL5 PTHR11157:SF18 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000004361.1|UniProtKB=W5MA03 W5MA03 ELP6 PTHR16184:SF6 ELONGATOR COMPLEX PROTEIN 6 ELONGATOR COMPLEX PROTEIN 6 elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000004375.1|UniProtKB=W5MA14 W5MA14 PTHR24412:SF490 KELCH PROTEIN BTB DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012460.1|UniProtKB=W5N3Y1 W5N3Y1 PTHR10218:SF85 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-13 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;dopamine receptor binding#GO:0050780;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052 membrane protein complex#GO:0098796;brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015899.1|UniProtKB=W5NG20 W5NG20 PTHR13964:SF24 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000000549.1|UniProtKB=W5LWY6 W5LWY6 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015205.1|UniProtKB=W5NDK2 W5NDK2 CIAO1 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000017379.1|UniProtKB=W5NLH5 W5NLH5 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012377.1|UniProtKB=W5N3N2 W5N3N2 PTHR10672:SF5 ADDUCIN GAMMA-ADDUCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;postsynapse#GO:0098794;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003277.1|UniProtKB=W5M656 W5M656 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN ML37 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016457.1|UniProtKB=W5NI75 W5NI75 PTHR22958:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;glycerophospholipid catabolic process#GO:0046475;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007693.1|UniProtKB=W5MLT6 W5MLT6 PTHR11889:SF84 HEDGEHOG HEDGEHOG PROTEIN cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;developmental process#GO:0032502;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000017949.1|UniProtKB=W5NN43 W5NN43 PTHR24156:SF6 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN 34C LEPOC|Ensembl=ENSLOCG00000010083.1|UniProtKB=W5MVC2 W5MVC2 LMOD3 PTHR10901:SF3 TROPOMODULIN LEIOMODIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003781.1|UniProtKB=W5M810 W5M810 PTHR24089:SF671 SOLUTE CARRIER FAMILY 25 DKFZP586G0123-LIKE carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017476.1|UniProtKB=W5NLS2 W5NLS2 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002684.1|UniProtKB=W5M463 W5M463 PTHR11455:SF9 CRYPTOCHROME CRYPTOCHROME CIRCADIAN CLOCK 5 ISOFORM X1 nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deoxyribodipyrimidine photo-lyase activity#GO:0003904;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;flavin adenine dinucleotide binding#GO:0050660;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 DNA metabolism protein#PC00009;DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501 LEPOC|Ensembl=ENSLOCG00000014393.1|UniProtKB=W5NAR2 W5NAR2 PTHR24103:SF692 E3 UBIQUITIN-PROTEIN LIGASE TRIM B30.2_SPRY DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001926.1|UniProtKB=W5M1H2 W5M1H2 PTHR20859:SF93 INTERFERON/INTERLEUKIN RECEPTOR CYTOKINE RECEPTOR FAMILY MEMBER B12-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012495.1|UniProtKB=W5N423 W5N423 PTHR10607:SF1 OSTEOPONTIN OSTEOPONTIN cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000003419.1|UniProtKB=W5M6R2 W5M6R2 PTHR24049:SF41 CRUMBS FAMILY MEMBER ATTRACTIN heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;establishment or maintenance of bipolar cell polarity#GO:0061245 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001524.1|UniProtKB=W5M036 W5M036 PTHR12290:SF2 CORNICHON-RELATED PHOSPHOPANTOTHENATE--CYSTEINE LIGASE membrane traffic protein#PC00150 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 LEPOC|Ensembl=ENSLOCG00000010496.1|UniProtKB=W5MWW2 W5MWW2 PTHR22811:SF184 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 10 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009191.1|UniProtKB=W5MS52 W5MS52 PTHR31206:SF5 LP10445P PROTEIN FAM177A1 LEPOC|Ensembl=ENSLOCG00000010603.1|UniProtKB=W5MX78 W5MX78 GFOD1 PTHR43818:SF2 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007989.1|UniProtKB=W5MMU0 W5MMU0 NAF1 PTHR31633:SF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000013640.1|UniProtKB=W5N863 W5N863 PTHR23239:SF180 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 17 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016819.1|UniProtKB=W5NJH8 W5NJH8 ADM2 PTHR23414:SF2 ADRENOMEDULLIN, ADM PROTEIN ADM2 blood circulation#GO:0008015;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000000961.1|UniProtKB=W5LY67 W5LY67 PTHR10707:SF12 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007810.1|UniProtKB=W5MM74 W5MM74 PTHR45695:SF7 LEUCOKININ RECEPTOR-RELATED GASTRIN-RELEASING PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006404.1|UniProtKB=W5MH81 W5MH81 PTHR13350:SF1 INTEGRATOR COMPLEX SUBUNIT 8 INTEGRATOR COMPLEX SUBUNIT 8 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 LEPOC|Ensembl=ENSLOCG00000013277.1|UniProtKB=W5N6U7 W5N6U7 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000015939.1|UniProtKB=W5NG73 W5NG73 SPAST PTHR23074:SF86 AAA DOMAIN-CONTAINING SPASTIN pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000017979.1|UniProtKB=W5NN71 W5NN71 PTHR15066:SF0 TRANSMEMBRANE PROTEIN 187 TRANSMEMBRANE PROTEIN 187 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003185.1|UniProtKB=W5M5X2 W5M5X2 PTHR43066:SF21 RHOMBOID-RELATED PROTEIN UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006590.1|UniProtKB=W5MHV2 W5MHV2 PTHR47238:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE HEMIPTEROUS non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555 LEPOC|Ensembl=ENSLOCG00000015477.1|UniProtKB=W5NEJ2 W5NEJ2 PTHR11787:SF3 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR ALPHA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015903.1|UniProtKB=W5NG24 W5NG24 PTHR12834:SF12 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003601.1|UniProtKB=W5M7A8 W5M7A8 PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 CHROMOSOME 7 OPEN READING FRAME 50 LEPOC|Ensembl=ENSLOCG00000017908.1|UniProtKB=W5NN02 W5NN02 PTHR46481:SF4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000004744.1|UniProtKB=W5MBF6 W5MBF6 PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011603.1|UniProtKB=W5N103 W5N103 PTHR24270:SF23 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;catabolic process#GO:0009056;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;multicellular organismal process#GO:0032501;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 LEPOC|Ensembl=ENSLOCG00000013728.1|UniProtKB=W5N8H0 W5N8H0 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008780.1|UniProtKB=W5MQN0 W5MQN0 PTHR19969:SF12 SH2-SH3 ADAPTOR PROTEIN-RELATED CYTOPLASMIC PROTEIN NCK2 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of translational initiation#GO:0006446;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;positive regulation of translation#GO:0045727;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to endoplasmic reticulum stress#GO:0034976;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of cell communication#GO:0010647;negative regulation of signal transduction#GO:0009968;regulation of translation#GO:0006417;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of amide metabolic process#GO:0034248;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cell migration#GO:0016477 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Nck#P00215;PDGF signaling pathway#P00047>Nck#P01147;T cell activation#P00053>nck#P01314 LEPOC|Ensembl=ENSLOCG00000016111.1|UniProtKB=W5NGU2 W5NGU2 PTHR35254:SF1 STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000005128.1|UniProtKB=W5MCR5 W5MCR5 PTHR24020:SF16 COLLAGEN ALPHA CARTILAGE MATRIX PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000002026.1|UniProtKB=W5M1T7 W5M1T7 PTHR28559:SF1 DNA REPAIR PROTEIN XRCC4 DNA REPAIR PROTEIN XRCC4 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;positive regulation of molecular function#GO:0044093;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;biological regulation#GO:0065007;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016384.1|UniProtKB=W5NHX7 W5NHX7 PTHR46269:SF3 EPIPHYCAN-RELATED EPIPHYCAN system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;skeletal system development#GO:0001501;tissue development#GO:0009888;bone development#GO:0060348 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005564.1|UniProtKB=W5MEB2 W5MEB2 PTHR46160:SF9 ALPHA-TECTORIN-RELATED PROTEIN PRY2-RELATED LEPOC|Ensembl=ENSLOCG00000018212.1|UniProtKB=W5NNV4 W5NNV4 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005138.1|UniProtKB=W5MCT0 W5MCT0 PTHR48092:SF18 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007454.1|UniProtKB=W5MKY3 W5MKY3 PTHR24343:SF301 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007187.1|UniProtKB=W5MJZ1 W5MJZ1 PTHR10519:SF74 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 LEPOC|Ensembl=ENSLOCG00000012168.1|UniProtKB=W5N2Y5 W5N2Y5 PTHR24180:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;positive regulation of Wnt signaling pathway#GO:0030177;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of chromosome organization#GO:0033044;regulation of cell communication#GO:0010646;regulation of organelle organization#GO:0033043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000016705.1|UniProtKB=W5NJ28 W5NJ28 PTPN14 PTHR45706:SF6 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 14 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 system development#GO:0048731;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;vasculature development#GO:0001944;multicellular organismal process#GO:0032501;anatomical structure formation involved in morphogenesis#GO:0048646 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000514.1|UniProtKB=W5LWR0 W5LWR0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017668.1|UniProtKB=W5NMB4 W5NMB4 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000001998.1|UniProtKB=W5M1P8 W5M1P8 PTHR23244:SF467 KELCH REPEAT DOMAIN EF-HAND DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015147.1|UniProtKB=W5NDD2 W5NDD2 PTHR14200:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012241.1|UniProtKB=W5N350 W5N350 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001106.1|UniProtKB=W5LYP0 W5LYP0 PTHR43580:SF2 OXIDOREDUCTASE GLYR1-RELATED CYTOKINE-LIKE NUCLEAR FACTOR N-PAC oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017500.1|UniProtKB=W5NLU6 W5NLU6 PTHR24237:SF7 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 183 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002891.1|UniProtKB=W5M4U3 W5M4U3 PTHR21345:SF5 SPIRE PROTEIN SPIRE HOMOLOG 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell division#GO:0051301;organelle localization#GO:0051640;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament organization#GO:0007015;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;spindle localization#GO:0051653;multicellular organismal reproductive process#GO:0048609;cellular component assembly#GO:0022607;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;vesicle-mediated transport#GO:0016192;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of spindle localization#GO:0051293;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015550.1|UniProtKB=W5NET6 W5NET6 PTHR14352:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000007524.1|UniProtKB=W5ML76 W5ML76 PTHR16154:SF26 NEURABIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 9 LIKE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 signal transduction#GO:0007165;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;cell projection organization#GO:0030030;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000007177.1|UniProtKB=W5MJX6 W5MJX6 PTHR12247:SF89 POLYCOMB GROUP PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008751.1|UniProtKB=W5MQK7 W5MQK7 PTHR45817:SF6 LYSYL OXIDASE-LIKE-RELATED PROTEIN-LYSINE 6-OXIDASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008405.1|UniProtKB=W5MPA5 W5MPA5 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015078.1|UniProtKB=W5ND46 W5ND46 PTHR10367:SF9 MRNA-CAPPING ENZYME DUAL-SPECIFICITY PHOSPHATASE 11 (RNA_RNP COMPLEX 1-INTERACTING) catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147;RNA metabolism protein#PC00031;mRNA capping factor#PC00145 LEPOC|Ensembl=ENSLOCG00000018302.1|UniProtKB=W5NP44 W5NP44 GPR151 PTHR24230:SF131 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 151 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003573.1|UniProtKB=W5M790 W5M790 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017867.1|UniProtKB=W5NMW1 W5NMW1 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000015148.1|UniProtKB=W5NDD1 W5NDD1 PTHR12329:SF10 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 4 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-folding chaperone binding#GO:0051087 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Apoptosis signaling pathway#P00006>SODD#P00320 LEPOC|Ensembl=ENSLOCG00000018363.1|UniProtKB=W5NPA5 W5NPA5 PTHR13976:SF87 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA BINDING MOTIF PROTEIN 12 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007844.1|UniProtKB=W5MMB9 W5MMB9 PTHR47135:SF3 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017305.1|UniProtKB=W5NLA1 W5NLA1 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016425.1|UniProtKB=W5NI28 W5NI28 PTHR10554:SF3 SYNTROPHIN GAMMA-2-SYNTROPHIN membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006011.1|UniProtKB=W5MFW0 W5MFW0 PTHR22938:SF0 ZINC FINGER PROTEIN 598 E3 UBIQUITIN-PROTEIN LIGASE ZNF598 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;peptide metabolic process#GO:0006518;protein modification process#GO:0036211;gene expression#GO:0010467;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;translation#GO:0006412;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;translational elongation#GO:0006414 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006507.1|UniProtKB=W5MHL5 W5MHL5 PTHR12546:SF36 FER-1-LIKE FER-1-LIKE PROTEIN 4 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016262.1|UniProtKB=W5NHE9 W5NHE9 PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011311.1|UniProtKB=W5MZU4 W5MZU4 PTHR19143:SF433 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;complement activation#GO:0006956 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009478.1|UniProtKB=W5MT59 W5MT59 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000015866.1|UniProtKB=W5NFX6 W5NFX6 PTHR24188:SF29 ANKYRIN REPEAT PROTEIN GH09064P LEPOC|Ensembl=ENSLOCG00000002381.1|UniProtKB=W5M338 W5M338 PTHR21373:SF0 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000013971.1|UniProtKB=W5N9B1 W5N9B1 PTHR12692:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED TUMOR SUPPRESSOR CANDIDATE 3 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017999.1|UniProtKB=W5NN91 W5NN91 PTHR24034:SF207 EGF-LIKE DOMAIN-CONTAINING PROTEIN CD248 MOLECULE extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000014590.1|UniProtKB=W5NBF5 W5NBF5 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 LEPOC|Ensembl=ENSLOCG00000014775.1|UniProtKB=W5NC33 W5NC33 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002332.1|UniProtKB=W5M2X5 W5M2X5 PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005043.1|UniProtKB=W5MCG3 W5MCG3 CLVS1 PTHR10174:SF72 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-1 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;organelle organization#GO:0006996 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000004037.1|UniProtKB=W5M8X6 W5M8X6 WDFY4 PTHR46108:SF3 BLUE CHEESE WD REPEAT- AND FYVE DOMAIN-CONTAINING PROTEIN 4 antigen processing and presentation#GO:0019882;immune system process#GO:0002376 LEPOC|Ensembl=ENSLOCG00000015875.1|UniProtKB=W5NG00 W5NG00 CADPS2 PTHR12166:SF7 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 2 positive regulation of secretion#GO:0051047;transport#GO:0006810;regulation of localization#GO:0032879;positive regulation of transport#GO:0051050;vesicle-mediated transport#GO:0016192;regulation of secretion by cell#GO:1903530;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157;export from cell#GO:0140352;secretion by cell#GO:0032940 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010825.1|UniProtKB=W5MY12 W5MY12 PTHR23282:SF150 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. SI:CH211-106H4.4 LEPOC|Ensembl=ENSLOCG00000007225.1|UniProtKB=W5MK45 W5MK45 PTHR46850:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010438.1|UniProtKB=W5MWN2 W5MWN2 PTHR24247:SF30 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;monoatomic cation transport#GO:0006812;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;transmembrane transport#GO:0055085;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;calcium ion transmembrane transport#GO:0070588;trans-synaptic signaling#GO:0099537;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000006872.1|UniProtKB=W5MIY8 W5MIY8 PTHR23220:SF23 INTEGRIN ALPHA INTEGRIN ALPHA-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000004177.1|UniProtKB=W5M9D3 W5M9D3 IL10RB PTHR20859:SF46 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interferon-gamma signaling pathway#P00035>IFNGR2#P00957;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interferon-gamma signaling pathway#P00035>IFNGR1#P00959 LEPOC|Ensembl=ENSLOCG00000014041.1|UniProtKB=W5N9J9 W5N9J9 PTHR46059:SF2 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015938.1|UniProtKB=W5NG65 W5NG65 PTHR19305:SF5 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 25 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000001376.1|UniProtKB=W5LZL1 W5LZL1 PTHR10252:SF8 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 LEPOC|Ensembl=ENSLOCG00000013043.1|UniProtKB=W5N611 W5N611 PTHR24064:SF192 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 23 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011357.1|UniProtKB=W5MZZ8 W5MZZ8 PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83A-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000014858.1|UniProtKB=W5NCD4 W5NCD4 PTHR23091:SF4 N-TERMINAL ACETYLTRANSFERASE N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000006074.1|UniProtKB=W5MG27 W5MG27 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification process#GO:0036211;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011436.1|UniProtKB=W5N096 W5N096 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003149.1|UniProtKB=W5M5Q5 W5M5Q5 C3orf33 PTHR28434:SF1 PROTEIN C3ORF33 PROTEIN C3ORF33 LEPOC|Ensembl=ENSLOCG00000001886.1|UniProtKB=W5M1C7 W5M1C7 PTHR24070:SF268 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN M-RAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 EGF receptor signaling pathway#P00018>Ras#P00552 LEPOC|Ensembl=ENSLOCG00000013426.1|UniProtKB=W5N7E8 W5N7E8 MTAP PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 LEPOC|Ensembl=ENSLOCG00000009941.1|UniProtKB=W5MUV2 W5MUV2 PTHR46221:SF4 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000017157.1|UniProtKB=W5NKP6 W5NKP6 PTHR23226:SF247 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN CONTAINING 24 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018359.1|UniProtKB=W5NPA1 W5NPA1 PTHR12307:SF4 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3D phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000004286.1|UniProtKB=W5M9R3 W5M9R3 PTHR23097:SF116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001000.1|UniProtKB=W5LYB7 W5LYB7 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005343.1|UniProtKB=W5MDH9 W5MDH9 PTHR34348:SF1 SURFEIT LOCUS PROTEIN 2 SURFEIT LOCUS PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000003121.1|UniProtKB=W5M5L3 W5M5L3 PTHR45972:SF1 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7A LEPOC|Ensembl=ENSLOCG00000003289.1|UniProtKB=W5M674 W5M674 PTHR12416:SF3 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN UTP23 HOMOLOG LEPOC|Ensembl=ENSLOCG00000012260.1|UniProtKB=W5N376 W5N376 PTHR10151:SF63 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009107.1|UniProtKB=W5MRU9 W5MRU9 PTHR10680:SF14 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE oxygenase#PC00177 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 LEPOC|Ensembl=ENSLOCG00000005427.1|UniProtKB=W5MDT9 W5MDT9 PTHR24178:SF2 MOLTING PROTEIN MLT-4 INVERSIN protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;regulation of heart contraction#GO:0008016;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;kidney development#GO:0001822;regulation of system process#GO:0044057;cellular process#GO:0009987;regulation of muscle system process#GO:0090257;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;protein localization to cell periphery#GO:1990778;system development#GO:0048731;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;sarcolemma#GO:0042383;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005826.1|UniProtKB=W5MF75 W5MF75 PTHR11639:SF114 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A14 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000000489.1|UniProtKB=W5LWM8 W5LWM8 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007866.1|UniProtKB=W5MMD9 W5MMD9 PTHR24251:SF31 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 2 peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;collagen binding#GO:0005518;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013700.1|UniProtKB=W5N8D8 W5N8D8 PIP4K2B PTHR23086:SF22 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000002796.1|UniProtKB=W5M4I2 W5M4I2 PTHR24414:SF27 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 10 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000002621.1|UniProtKB=W5M3X8 W5M3X8 PTHR10281:SF4 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUFERRICIN cellular anatomical entity#GO:0110165;membrane#GO:0016020;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007903.1|UniProtKB=W5MMJ2 W5MMJ2 PTHR10117:SF6 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;fertilization#GO:0009566;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;single fertilization#GO:0007338;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;reproduction#GO:0000003;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;sexual reproduction#GO:0019953;reproductive process#GO:0022414;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000001827.1|UniProtKB=W5M157 W5M157 PTHR11438:SF4 PROENKEPHALIN PROENKEPHALIN-B protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;cell body#GO:0044297;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 neuropeptide#PC00162;peptide hormone#PC00179 Enkephalin release#P05913>Enkephalin#P05976;Opioid prodynorphin pathway#P05916>dynorphin#P06003;Opioid prodynorphin pathway#P05916>preprodynorphin#G06047;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Opioid prodynorphin pathway#P05916>prodynorphin#P05997;Opioid prodynorphin pathway#P05916>preprodynorphin#G06049;Enkephalin release#P05913>preproenkephalin#G06045 LEPOC|Ensembl=ENSLOCG00000002012.1|UniProtKB=W5M1Z9 W5M1Z9 PTHR23122:SF40 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PERIPHERAL PLASMA MEMBRANE PROTEIN CASK protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 basal plasma membrane#GO:0009925;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>CASK#P01232;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847 LEPOC|Ensembl=ENSLOCG00000016943.1|UniProtKB=W5NJY5 W5NJY5 PTHR24203:SF45 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN 6 LEPOC|Ensembl=ENSLOCG00000017605.1|UniProtKB=W5NM51 W5NM51 PTHR13546:SF12 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85B negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011772.1|UniProtKB=W5N1G3 W5N1G3 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009803.1|UniProtKB=W5MUC2 W5MUC2 TNIP3 PTHR31882:SF2 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 3 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to lipopolysaccharide#GO:0071222;regulation of transcription by RNA polymerase II#GO:0006357;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;response to lipopolysaccharide#GO:0032496;cellular response to molecule of bacterial origin#GO:0071219;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000008313.1|UniProtKB=W5MNZ0 W5MNZ0 PLBD2 PTHR12370:SF3 PHOSPHOLIPASE B-RELATED PHOSPHOLIPASE B-LIKE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010658.1|UniProtKB=W5MXI5 W5MXI5 PTHR48015:SF2 SERINE/THREONINE-PROTEIN KINASE TAO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 LEPOC|Ensembl=ENSLOCG00000014397.1|UniProtKB=W5NAR7 W5NAR7 ARRDC4 PTHR11188:SF16 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 4 ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016381.1|UniProtKB=W5NHX5 W5NHX5 PTHR10357:SF179 ALPHA-AMYLASE FAMILY MEMBER NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 amylase#PC00048;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013246.1|UniProtKB=W5N6Q6 W5N6Q6 PTHR24225:SF72 CHEMOTACTIC RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006298.1|UniProtKB=W5MGW9 W5MGW9 PTHR47385:SF20 CALPONIN TRANSGELIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014039.1|UniProtKB=W5N9J8 W5N9J8 PTHR24034:SF158 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN 2 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013687.1|UniProtKB=W5N8B4 W5N8B4 PTHR45740:SF7 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011472.1|UniProtKB=W5N0D7 W5N0D7 PTHR12322:SF70 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sex differentiation#GO:0007548;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015210.1|UniProtKB=W5NDK8 W5NDK8 PTHR11662:SF207 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 3 L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;acidic amino acid transmembrane transporter activity#GO:0015172 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;regulation of synapse structure or activity#GO:0050803;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052;vesicle-mediated transport in synapse#GO:0099003 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 secondary carrier transporter#PC00258;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 LEPOC|Ensembl=ENSLOCG00000010593.1|UniProtKB=W5MX59 W5MX59 PTHR12121:SF45 CARBON CATABOLITE REPRESSOR PROTEIN 4 NOCTURNIN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000004770.1|UniProtKB=W5MBI9 W5MBI9 PTHR32341:SF10 INTERFERON-INDUCIBLE GTPASE INTERFERON-INDUCIBLE GTPASE 5 LEPOC|Ensembl=ENSLOCG00000012885.1|UniProtKB=W5N5G1 W5N5G1 PTHR45721:SF16 LAMIN DM0-RELATED LAMIN-L(III) structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;nuclear migration#GO:0007097;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;establishment of organelle localization#GO:0051656;negative regulation of cellular process#GO:0048523;localization within membrane#GO:0051668;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular macromolecule localization#GO:0070727;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;chromatin organization#GO:0006325;intracellular transport#GO:0046907;nuclear envelope organization#GO:0006998;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;protein-containing complex localization#GO:0031503 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear periphery#GO:0034399;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 FAS signaling pathway#P00020>Nuclear Lamin#P00616 LEPOC|Ensembl=ENSLOCG00000006992.1|UniProtKB=W5MJA1 W5MJA1 XAB2 PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000001597.1|UniProtKB=W5M0D8 W5M0D8 PTHR11903:SF8 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 2 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CCKR signaling map#P06959>COX2#G07292;Endothelin signaling pathway#P00019>COX-2#P00582;Toll receptor signaling pathway#P00054>Gene trancription#G01550;CCKR signaling map#P06959>COX2#P07080;CCKR signaling map#P06959>COX2#G06998;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 LEPOC|Ensembl=ENSLOCG00000015709.1|UniProtKB=W5NFC9 W5NFC9 SEC61A2 PTHR10906:SF10 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 2 signal sequence binding#GO:0005048;transmembrane transporter activity#GO:0022857;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein transmembrane transporter activity#GO:0008320;protein-containing complex binding#GO:0044877;transporter activity#GO:0005215 cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;post-translational protein targeting to membrane, translocation#GO:0031204;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008174.1|UniProtKB=W5MNG5 W5MNG5 PTHR23163:SF2 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1A transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001862.1|UniProtKB=W5M1A3 W5M1A3 PTHR22957:SF598 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 26 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000012113.1|UniProtKB=W5N2P0 W5N2P0 PTHR34262:SF1 TRANSMEMBRANE PROTEIN 220 TRANSMEMBRANE PROTEIN 220 LEPOC|Ensembl=ENSLOCG00000012181.1|UniProtKB=W5N2X4 W5N2X4 PTHR10660:SF4 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 3 peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of proteolysis#GO:0030162;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of catalytic activity#GO:0043085;regulation of cell cycle phase transition#GO:1901987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of mitotic cell cycle#GO:0007346;positive regulation of endopeptidase activity#GO:0010950;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000005996.1|UniProtKB=W5MFT9 W5MFT9 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014999.1|UniProtKB=W5NCW3 W5NCW3 PTHR24367:SF10 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 3 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of exocytosis#GO:0017157 presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000013865.1|UniProtKB=W5N8Z3 W5N8Z3 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;kinase activity#GO:0016301;ATP binding#GO:0005524 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;hexose biosynthetic process#GO:0019319;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 LEPOC|Ensembl=ENSLOCG00000006780.1|UniProtKB=W5MII4 W5MII4 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;establishment of localization#GO:0051234;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;chromosome localization#GO:0050000;establishment of organelle localization#GO:0051656;metaphase chromosome alignment#GO:0051310 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;outer kinetochore#GO:0000940;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011142.1|UniProtKB=W5MZ81 W5MZ81 PTHR12673:SF13 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008591.1|UniProtKB=W5MPY9 W5MPY9 PTHR45656:SF8 PROTEIN CBR-CLEC-78 SEIZURE 6-LIKE PROTEIN regulation of cell communication#GO:0010646;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cell body#GO:0044297;neuronal cell body#GO:0043025;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005015.1|UniProtKB=W5MCF1 W5MCF1 PTHR43829:SF7 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;amide transmembrane transporter activity#GO:0042887;channel activity#GO:0015267;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;water transport#GO:0006833;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;fluid transport#GO:0042044 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014777.1|UniProtKB=W5NC36 W5NC36 PTHR22765:SF405 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF128 PRECURSOR transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007885.1|UniProtKB=W5MMG8 W5MMG8 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000013781.1|UniProtKB=W5N8N8 W5N8N8 PTHR10410:SF2 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED BRCA1_BRCA2-CONTAINING COMPLEX SUBUNIT 3 metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;BRCA1-A complex#GO:0070531;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000005332.1|UniProtKB=W5MDG6 W5MDG6 PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016960.1|UniProtKB=W5NK08 W5NK08 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013560.1|UniProtKB=W5N7V8 W5N7V8 LSM3 PTHR13110:SF0 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 LSM3 HOMOLOG, U6 SMALL NUCLEAR RNA AND MRNA DEGRADATION ASSOCIATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;P-body assembly#GO:0033962;non-membrane-bounded organelle assembly#GO:0140694;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013264.1|UniProtKB=W5N6U1 W5N6U1 PTHR11474:SF3 TYROSINASE FAMILY MEMBER 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental pigmentation#GO:0048066;organelle organization#GO:0006996;melanosome organization#GO:0032438;developmental process#GO:0032502;pigmentation#GO:0043473;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;melanocyte differentiation#GO:0030318 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009860.1|UniProtKB=W5MUN0 W5MUN0 PTHR44170:SF45 PROTEIN SIDEKICK NEURAL CELL ADHESION MOLECULE L1-LIKE PROTEIN ISOFORM X1 cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;head development#GO:0060322;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014602.1|UniProtKB=W5NBG3 W5NBG3 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015525.1|UniProtKB=W5NEP9 W5NEP9 C2orf73 PTHR35087:SF1 SIMILAR TO HYPOTHETICAL PROTEIN FLJ40298 RIKEN CDNA 4930505A04 GENE LEPOC|Ensembl=ENSLOCG00000007209.1|UniProtKB=W5MK19 W5MK19 NOX4 PTHR11972:SF206 NADPH OXIDASE NADPH OXIDASE 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015421.1|UniProtKB=W5NEB7 W5NEB7 PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000016292.1|UniProtKB=W5NHJ7 W5NHJ7 PTHR13962:SF19 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000006717.1|UniProtKB=W5MIA5 W5MIA5 PTHR11022:SF66 PEPTIDOGLYCAN RECOGNITION PROTEIN N-ACETYLMURAMOYL-L-ALANINE AMIDASE defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002016.1|UniProtKB=W5M1T0 W5M1T0 PTHR11767:SF44 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 11 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014109.1|UniProtKB=W5N9S3 W5N9S3 PTHR21771:SF0 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000004166.1|UniProtKB=W5M9C3 W5M9C3 PTHR10153:SF41 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;calmodulin binding#GO:0005516;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;protein binding#GO:0005515;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000006930.1|UniProtKB=W5MJ22 W5MJ22 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014903.1|UniProtKB=W5NCJ2 W5NCJ2 PTHR16236:SF0 TRANSMEMBRANE PROTEIN 160 TRANSMEMBRANE PROTEIN 160 LEPOC|Ensembl=ENSLOCG00000018153.1|UniProtKB=W5NNP5 W5NNP5 HCAR1 PTHR46048:SF6 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004701.1|UniProtKB=W5MB88 W5MB88 PTHR22804:SF11 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 synapse#GO:0045202;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000012087.1|UniProtKB=W5N2L7 W5N2L7 PTHR10454:SF31 CASPASE CASPASE-7 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase7#P00595;Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605 LEPOC|Ensembl=ENSLOCG00000015290.1|UniProtKB=W5NDV1 W5NDV1 PTHR23245:SF25 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510;glycosyl compound metabolic process#GO:1901657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000010514.1|UniProtKB=W5MWX1 W5MWX1 PTHR10250:SF13 MICROSOMAL GLUTATHIONE S-TRANSFERASE MICROSOMAL GLUTATHIONE S-TRANSFERASE 2 glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010472.1|UniProtKB=W5MWT2 W5MWT2 PTHR12062:SF27 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007790.1|UniProtKB=W5MM46 W5MM46 PTHR20932:SF2 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 1-RELATED LEPOC|Ensembl=ENSLOCG00000001443.1|UniProtKB=W5LZU5 W5LZU5 PTHR12688:SF2 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000007419.1|UniProtKB=W5MKU4 W5MKU4 PTHR12080:SF93 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of multicellular organismal process#GO:0051239;cell projection organization#GO:0030030;filopodium assembly#GO:0046847;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;positive regulation of cellular component biogenesis#GO:0044089;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003207.1|UniProtKB=W5M5Y5 W5M5Y5 PTHR28652:SF3 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59 regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of autophagy#GO:0010508;regulation of cellular catabolic process#GO:0031329;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cellular metabolic process#GO:0031323 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000010541.1|UniProtKB=W5MX07 W5MX07 PTHR15191:SF8 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE 1 PROTEIN-INTERACTING PROTEIN-LIKE cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006667.1|UniProtKB=W5MI77 W5MI77 PTHR11216:SF68 EH DOMAIN INTERSECTIN-1 endosomal transport#GO:0016197;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;localization#GO:0051179;synaptic vesicle recycling#GO:0036465;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;vesicle#GO:0031982;presynaptic membrane#GO:0042734;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003810.1|UniProtKB=W5M850 W5M850 PTHR12891:SF0 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014101.1|UniProtKB=W5N9R5 W5N9R5 PTHR15871:SF2 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 2 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 LEPOC|Ensembl=ENSLOCG00000010528.1|UniProtKB=W5MWZ3 W5MWZ3 PTHR19143:SF25 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007377.1|UniProtKB=W5MKN8 W5MKN8 PTHR24054:SF28 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE 2 ALPHA 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 LEPOC|Ensembl=ENSLOCG00000007668.1|UniProtKB=W5MLQ4 W5MLQ4 PTHR12296:SF21 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 3 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000599.1|UniProtKB=W5LX01 W5LX01 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005390.1|UniProtKB=W5MDN6 W5MDN6 PTHR24271:SF55 KALLIKREIN-RELATED SERINE PROTEASE 57 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008489.1|UniProtKB=W5MPM4 W5MPM4 PTHR16171:SF13 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED BASIC IMMUNOGLOBULIN-LIKE VARIABLE MOTIF-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012941.1|UniProtKB=W5N5M6 W5N5M6 PTHR10388:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1B nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015532.1|UniProtKB=W5NEQ6 W5NEQ6 PTHR34639:SF1 PROTEIN FLATTOP PROTEIN FLATTOP cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002554.1|UniProtKB=W5M3N7 W5M3N7 PTHR11592:SF7 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 8-RELATED oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002388.1|UniProtKB=W5M336 W5M336 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006262.1|UniProtKB=W5MGQ8 W5MGQ8 PTHR23142:SF1 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38A ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010255.1|UniProtKB=W5MVZ4 W5MVZ4 PTHR11134:SF4 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-4 COMPLEX SUBUNIT BETA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018054.1|UniProtKB=W5NNE6 W5NNE6 PTHR11829:SF392 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000017837.1|UniProtKB=W5NMT1 W5NMT1 PTHR24373:SF394 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011279.1|UniProtKB=W5MZQ3 W5MZQ3 PTHR15715:SF21 CENTROSOMAL PROTEIN OF 170 KDA TRAF3-INTERACTING JNK-ACTIVATING MODULATOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000640.1|UniProtKB=W5LX50 W5LX50 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016914.1|UniProtKB=W5NJV2 W5NJV2 PTHR28575:SF1 MEIOSIS-SPECIFIC PROTEIN MEI4 MEIOSIS-SPECIFIC PROTEIN MEI4 cellular aromatic compound metabolic process#GO:0006725;male gamete generation#GO:0048232;homologous chromosome segregation#GO:0045143;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;cell differentiation#GO:0030154;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;germ cell development#GO:0007281;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;nuclear chromosome segregation#GO:0098813;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;oogenesis#GO:0048477;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;meiotic DNA double-strand break formation#GO:0042138;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;organelle fission#GO:0048285;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 LEPOC|Ensembl=ENSLOCG00000013521.1|UniProtKB=W5N7Q9 W5N7Q9 PTHR10519:SF20 GABA-B RECEPTOR G-PROTEIN COUPLED RECEPTOR 156-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013197.1|UniProtKB=W5N6L7 W5N6L7 FBN1 PTHR24040:SF8 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 1 LEPOC|Ensembl=ENSLOCG00000001092.1|UniProtKB=W5LYM9 W5LYM9 PTHR14586:SF1 THIAMINE-TRIPHOSPHATASE THIAMINE-TRIPHOSPHATASE cation binding#GO:0043169;pyrophosphatase activity#GO:0016462;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;metal ion binding#GO:0046872;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;sulfur compound metabolic process#GO:0006790;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181;hydrolase#PC00121 Thiamin metabolism#P02780>Thiamine triphosphatase#P03184 LEPOC|Ensembl=ENSLOCG00000011109.1|UniProtKB=W5MZ36 W5MZ36 PTHR24332:SF16 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012543.1|UniProtKB=W5N490 W5N490 PTHR11006:SF49 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007675.1|UniProtKB=W5MLQ2 W5MLQ2 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010813.1|UniProtKB=W5MXZ1 W5MXZ1 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011515.1|UniProtKB=W5N0I8 W5N0I8 PTHR31774:SF14 PROTEIN SHISA-9-RELATED PROTEIN SHISA-8 regulation of cell communication#GO:0010646;regulation of transmembrane transport#GO:0034762;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of neuronal synaptic plasticity#GO:0048168;regulation of transporter activity#GO:0032409 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;cell projection membrane#GO:0031253;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005191.1|UniProtKB=W5MCZ0 W5MCZ0 PTHR24418:SF265 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 6 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000004342.1|UniProtKB=W5M9X3 W5M9X3 PTHR24118:SF51 POTE ANKYRIN DOMAIN B-CELL LYMPHOMA 3 PROTEIN membrane traffic protein#PC00150 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 LEPOC|Ensembl=ENSLOCG00000015157.1|UniProtKB=W5NDE4 W5NDE4 PTHR11486:SF77 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 13 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of sodium ion transport#GO:0002028;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of metal ion transport#GO:0010959;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular developmental process#GO:0048869;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000002168.1|UniProtKB=W5M2D1 W5M2D1 ADAMTS13 PTHR13723:SF20 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 13 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006543.1|UniProtKB=W5MHP6 W5MHP6 PTHR15698:SF8 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008886.1|UniProtKB=W5MR03 W5MR03 PTHR15819:SF9 TRANSMEMBRANE PROTEIN FAM155 NALCN CHANNEL AUXILIARY FACTOR 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010725.1|UniProtKB=W5MXN2 W5MXN2 ENOPH1 PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017070.1|UniProtKB=W5NKD8 W5NKD8 PTHR43108:SF5 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-ACETYLGLUCOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005291.1|UniProtKB=W5MDC4 W5MDC4 PTHR13497:SF3 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000001123.1|UniProtKB=W5LZ27 W5LZ27 PTHR24270:SF20 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B ISOFORM X1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000014264.1|UniProtKB=W5NA99 W5NA99 PTHR23280:SF34 4.1 G PROTEIN FERM DOMAIN CONTAINING 7 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000018339.1|UniProtKB=W5NP81 W5NP81 PTHR15467:SF5 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000013316.1|UniProtKB=W5N703 W5N703 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic cation transport#GO:0015695;transport#GO:0006810;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011785.1|UniProtKB=W5N1K5 W5N1K5 PTHR12930:SF0 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113B cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017246.1|UniProtKB=W5NL22 W5NL22 PTHR11630:SF48 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM9 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001674.1|UniProtKB=W5M0L9 W5M0L9 PTHR15031:SF4 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016644.1|UniProtKB=W5NIZ3 W5NIZ3 PTHR46116:SF39 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015562.1|UniProtKB=W5NEV1 W5NEV1 PTHR43195:SF4 TRANSKETOLASE TRANSKETOLASE-LIKE PROTEIN 2 cation binding#GO:0043169;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 metabolite interconversion enzyme#PC00262;transketolase#PC00221 LEPOC|Ensembl=ENSLOCG00000004269.1|UniProtKB=W5M9Q1 W5M9Q1 PTHR24351:SF188 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016000.1|UniProtKB=W5NGE8 W5NGE8 PTPN12 PTHR45983:SF3 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Integrin signalling pathway#P00034>PTP-PEST#P00915 LEPOC|Ensembl=ENSLOCG00000003143.1|UniProtKB=W5M5P6 W5M5P6 PTHR16200:SF3 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013192.1|UniProtKB=W5N6I8 W5N6I8 PTHR14334:SF2 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN BETA CHAIN immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of immune response#GO:0050778;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;response to stimulus#GO:0050896;immune system process#GO:0002376;B cell differentiation#GO:0030183;lymphocyte differentiation#GO:0030098;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 B cell activation#P00010>Ig-beta#P00377 LEPOC|Ensembl=ENSLOCG00000007981.1|UniProtKB=W5MMV0 W5MMV0 PTHR22767:SF3 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000014182.1|UniProtKB=W5NA11 W5NA11 PTHR11984:SF107 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000010765.1|UniProtKB=W5MXT5 W5MXT5 PTHR11360:SF21 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 6 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002362.1|UniProtKB=W5M312 W5M312 PTHR24103:SF629 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM39 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013623.1|UniProtKB=W5N857 W5N857 PTHR22625:SF36 PLEXIN PLEXIN-B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;regulation of GTPase activity#GO:0043087;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of nervous system development#GO:0051962;positive regulation of developmental process#GO:0051094;regulation of neuron projection development#GO:0010975;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of multicellular organismal process#GO:0051240 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>plexinB1#P00328 LEPOC|Ensembl=ENSLOCG00000006779.1|UniProtKB=W5MII3 W5MII3 PTHR12864:SF19 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 10 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002087.1|UniProtKB=W5M261 W5M261 PTHR45674:SF9 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271 DNA ligase#PC00012 LEPOC|Ensembl=ENSLOCG00000013513.1|UniProtKB=W5N7Q6 W5N7Q6 PTHR12245:SF15 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2-LIKE ISOFORM X1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011968.1|UniProtKB=W5N275 W5N275 PTHR10082:SF25 INTEGRIN BETA SUBUNIT INTEGRIN BETA-3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;platelet activation#GO:0030168;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;regulation of body fluid levels#GO:0050878;homotypic cell-cell adhesion#GO:0034109;wound healing#GO:0042060;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;cell activation#GO:0001775;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611;platelet aggregation#GO:0070527;regulation of biological quality#GO:0065008;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Blood coagulation#P00011>GP IIIa#P00458;Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000014084.1|UniProtKB=W5N9P6 W5N9P6 PTHR10552:SF6 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011926.1|UniProtKB=W5N200 W5N200 PTHR16705:SF7 COMPLEXIN COMPLEXIN-4 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;SNARE complex#GO:0031201;cell junction#GO:0030054;terminal bouton#GO:0043195;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000017091.1|UniProtKB=W5NKG2 W5NKG2 PTHR13935:SF106 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE COMPLEX PROTEIN T5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010750.1|UniProtKB=W5MXR0 W5MXR0 FDX1 PTHR23426:SF75 FERREDOXIN/ADRENODOXIN ADRENODOXIN cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012771.1|UniProtKB=W5N506 W5N506 PTHR20516:SF1 TRANSMEMBRANE PROTEIN 114/235 FAMILY MEMBER TRANSMEMBRANE PROTEIN 235 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 LEPOC|Ensembl=ENSLOCG00000007288.1|UniProtKB=W5MKB5 W5MKB5 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER-RELATED transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010787.1|UniProtKB=W5MXV9 W5MXV9 PTHR45620:SF8 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 neuron projection#GO:0043005;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004574.1|UniProtKB=W5MAR7 W5MAR7 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B LEPOC|Ensembl=ENSLOCG00000017492.1|UniProtKB=W5NLT8 W5NLT8 PTHR24248:SF176 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 101-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000073.1|UniProtKB=W5LVC9 W5LVC9 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013279.1|UniProtKB=W5N6W0 W5N6W0 PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000015051.1|UniProtKB=W5ND19 W5ND19 PTHR12346:SF2 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771;p53 pathway#P00059>Sin3#P04622 LEPOC|Ensembl=ENSLOCG00000000585.1|UniProtKB=W5LWZ0 W5LWZ0 PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 LEPOC|Ensembl=ENSLOCG00000008833.1|UniProtKB=W5MQU4 W5MQU4 PTHR43176:SF3 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016183.1|UniProtKB=W5NH36 W5NH36 PTHR12546:SF32 FER-1-LIKE OTOFERLIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012789.1|UniProtKB=W5N528 W5N528 PTHR14919:SF0 KPL2-RELATED SPERM FLAGELLAR PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004389.1|UniProtKB=W5MAF0 W5MAF0 PTHR10663:SF137 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010684.1|UniProtKB=W5MXI4 W5MXI4 PTHR22792:SF50 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006519.1|UniProtKB=W5MHL2 W5MHL2 PTHR21399:SF0 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;pICln-Sm protein complex#GO:0034715;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006688.1|UniProtKB=W5MI71 W5MI71 PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;sulfur compound catabolic process#GO:0044273;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013188.1|UniProtKB=W5N6I6 W5N6I6 PTHR34035:SF1 TESTIS-EXPRESSED PROTEIN 47 TESTIS-EXPRESSED PROTEIN 47 LEPOC|Ensembl=ENSLOCG00000000718.1|UniProtKB=W5LXF2 W5LXF2 PTHR46199:SF2 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular component biogenesis#GO:0044085;cell division#GO:0051301;signal transduction#GO:0007165;mitotic spindle organization#GO:0007052;small GTPase-mediated signal transduction#GO:0007264;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;spindle elongation#GO:0051231;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;cytoskeleton-dependent cytokinesis#GO:0061640;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;non-membrane-bounded organelle assembly#GO:0140694;cytokinesis#GO:0000910;signaling#GO:0023052;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;cellular response to stimulus#GO:0051716;sister chromatid segregation#GO:0000819;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285 spindle midzone#GO:0051233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell division site#GO:0032153;cytoskeleton#GO:0005856;spindle#GO:0005819;plasma membrane#GO:0005886 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005560.1|UniProtKB=W5MEA3 W5MEA3 PTHR11588:SF6 TUBULIN TUBULIN_FTSZ GTPASE DOMAIN-CONTAINING PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017283.1|UniProtKB=W5NL70 W5NL70 PTHR19134:SF209 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005004.1|UniProtKB=W5MCC4 W5MCC4 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE 120 KDA PROTEIN, MITOCHONDRIAL GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 mitochondrial fusion#GO:0008053;organelle localization#GO:0051640;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;peroxisome organization#GO:0007031;import into cell#GO:0098657;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitochondrial envelope#GO:0005740;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;cytoskeleton#GO:0005856;microtubule#GO:0005874 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018129.1|UniProtKB=W5NNM1 W5NNM1 CYP8B1 PTHR24306:SF0 FAMILY NOT NAMED 7-ALPHA-HYDROXYCHOLEST-4-EN-3-ONE 12-ALPHA-HYDROXYLASE steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 LEPOC|Ensembl=ENSLOCG00000008368.1|UniProtKB=W5MP56 W5MP56 PTHR22950:SF458 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001083.1|UniProtKB=W5LYN8 W5LYN8 PTHR11835:SF42 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008048.1|UniProtKB=W5MN15 W5MN15 PTHR23311:SF5 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA LEPOC|Ensembl=ENSLOCG00000014336.1|UniProtKB=W5NAJ5 W5NAJ5 EIF3K PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;translation regulator activity, nucleic acid binding#GO:0090079;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002472.1|UniProtKB=W5M3E3 W5M3E3 TUT7 PTHR12271:SF34 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 7 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000015347.1|UniProtKB=W5NE28 W5NE28 PTHR45789:SF3 FI18025P1 TRANSCRIPTION FACTOR SOX-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004219.1|UniProtKB=W5M9I2 W5M9I2 PTHR14002:SF59 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005048.1|UniProtKB=W5MCH8 W5MCH8 PTHR46961:SF8 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 7 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012667.1|UniProtKB=W5N4N3 W5N4N3 PTHR11055:SF17 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 LEPOC|Ensembl=ENSLOCG00000013305.1|UniProtKB=W5N6Z3 W5N6Z3 PTHR24291:SF43 CYTOCHROME P450 FAMILY 4 AROMATASE oxygenase#PC00177;oxidoreductase#PC00176 Androgen/estrogene/progesterone biosynthesis#P02727>Aromatase#P02828 LEPOC|Ensembl=ENSLOCG00000010997.1|UniProtKB=W5MYN1 W5MYN1 PTHR11548:SF2 THYMIDYLATE SYNTHASE 1 THYMIDYLATE SYNTHASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Thymidylate synthase#P02954;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 LEPOC|Ensembl=ENSLOCG00000011913.1|UniProtKB=W5N1Y8 W5N1Y8 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016141.1|UniProtKB=W5NGY1 W5NGY1 PTHR45787:SF7 LD11652P LIM DOMAIN ONLY PROTEIN 3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006275.1|UniProtKB=W5MGS3 W5MGS3 MMP23B PTHR10201:SF7 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-23 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000000353.1|UniProtKB=W5LW78 W5LW78 PTHR46105:SF12 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010510.1|UniProtKB=W5MWX5 W5MWX5 PTHR10155:SF3 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;response to insulin#GO:0032868;phosphatidylinositol biosynthetic process#GO:0006661;response to peptide hormone#GO:0043434;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;glycerophospholipid biosynthetic process#GO:0046474;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p85#P01202;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;CCKR signaling map#P06959>p85#P07212;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936;Gonadotropin-releasing hormone receptor pathway#P06664>PI3K#P06766 LEPOC|Ensembl=ENSLOCG00000010990.1|UniProtKB=W5MYM1 W5MYM1 PTHR11950:SF40 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;ossification#GO:0001503;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Runt transcription factor#PC00254;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000006905.1|UniProtKB=W5MIZ3 W5MIZ3 PTHR12932:SF24 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012494.1|UniProtKB=W5N435 W5N435 UBA6 PTHR10953:SF186 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 6 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000001763.1|UniProtKB=W5M0Y8 W5M0Y8 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001410.1|UniProtKB=W5LZQ0 W5LZQ0 PTHR22776:SF89 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001044.1|UniProtKB=W5LYG6 W5LYG6 PTHR11127:SF2 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008148.1|UniProtKB=W5MND2 W5MND2 PTHR46916:SF2 TRANSMEMBRANE PROTEIN 205 TRANSMEMBRANE PROTEIN 205 LEPOC|Ensembl=ENSLOCG00000000149.1|UniProtKB=W5LVL0 W5LVL0 KATNAL1 PTHR23074:SF65 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012169.1|UniProtKB=W5N2W2 W5N2W2 PIGG PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013053.1|UniProtKB=W5N623 W5N623 PTHR11771:SF96 LIPOXYGENASE 12-LIPOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002202.1|UniProtKB=W5M2J5 W5M2J5 MME PTHR11733:SF114 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000877.1|UniProtKB=W5LXX5 W5LXX5 PTHR46102:SF3 AXIN AXIN-1 SMAD binding#GO:0046332;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;identical protein binding#GO:0042802;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;ubiquitin protein ligase binding#GO:0031625;beta-catenin binding#GO:0008013;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of protein modification process#GO:0031401;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;negative regulation of signaling#GO:0023057;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of protein catabolic process#GO:0045732;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of cellular process#GO:0048523;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of transferase activity#GO:0051338;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 LEPOC|Ensembl=ENSLOCG00000016086.1|UniProtKB=W5NGR1 W5NGR1 PTHR21199:SF1 COMM DOMAIN-CONTAINING PROTEIN 1 COMM DOMAIN-CONTAINING PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of sodium ion transport#GO:0002028;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of monoatomic ion transport#GO:0043269;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein localization#GO:0032880;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of proteolysis#GO:0030162;regulation of transmembrane transport#GO:0034762;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;negative regulation of transport#GO:0051051;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular localization#GO:0060341;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006516.1|UniProtKB=W5N893 W5N893 PTHR12190:SF4 A-KINASE ANCHOR PROTEIN AKAP 8 A-KINASE ANCHOR PROTEIN 8-LIKE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009304.1|UniProtKB=W5MSI8 W5MSI8 SPEGNB PTHR47633:SF8 IMMUNOGLOBULIN SPEG NEIGHBOR PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 LEPOC|Ensembl=ENSLOCG00000000584.1|UniProtKB=W5LWZ4 W5LWZ4 EIF2C4 PTHR22891:SF26 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-4 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;pre-miRNA processing#GO:0031054;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000005813.1|UniProtKB=W5MF64 W5MF64 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 LEPOC|Ensembl=ENSLOCG00000004622.1|UniProtKB=W5MAY0 W5MAY0 PTHR11636:SF46 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011807.1|UniProtKB=W5N1L1 W5N1L1 PTHR23235:SF141 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012196.1|UniProtKB=W5N2Z1 W5N2Z1 PTHR12591:SF5 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003958.1|UniProtKB=W5M8L8 W5M8L8 PTHR11232:SF80 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN ISOFORM X1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004722.1|UniProtKB=W5MBA5 W5MBA5 PTHR23180:SF241 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000013622.1|UniProtKB=W5N837 W5N837 PTHR24251:SF27 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;positive regulation of signal transduction#GO:0009967;regulation of membrane potential#GO:0042391;regulation of signaling#GO:0023051;regulation of system process#GO:0044057;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015219.1|UniProtKB=W5NDM4 W5NDM4 PTHR24356:SF160 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011124.1|UniProtKB=W5MZ54 W5MZ54 PTHR10424:SF81 VIRAL ENVELOPE PROTEIN ERVV2 PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000017669.1|UniProtKB=W5NMB5 W5NMB5 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012889.1|UniProtKB=W5N5F7 W5N5F7 PTHR36687:SF1 GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2-RELATED GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 LEPOC|Ensembl=ENSLOCG00000003508.1|UniProtKB=W5M6Z8 W5M6Z8 PTHR11516:SF60 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266;Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 LEPOC|Ensembl=ENSLOCG00000017832.1|UniProtKB=W5NMS6 W5NMS6 PTHR23074:SF14 AAA DOMAIN-CONTAINING FIDGETIN pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000006060.1|UniProtKB=W5MG30 W5MG30 PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007249.1|UniProtKB=W5MK65 W5MK65 PTHR10984:SF25 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;coated vesicle#GO:0030135;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001145.1|UniProtKB=W5LYT5 W5LYT5 PTHR12308:SF40 ANOCTAMIN ANOCTAMIN-10 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004652.1|UniProtKB=W5MB28 W5MB28 PTHR13681:SF24 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED TUDOR DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005639.1|UniProtKB=W5MEK0 W5MEK0 PTHR11370:SF5 DNA-REPAIR PROTEIN XRCC1 DNA REPAIR PROTEIN XRCC1 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008767.1|UniProtKB=W5MQM6 W5MQM6 PTHR11596:SF76 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008806.1|UniProtKB=W5MQS5 W5MQS5 PTHR45024:SF2 DEHYDROGENASES, SHORT CHAIN SCP2 DOMAIN-CONTAINING PROTEIN dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009762.1|UniProtKB=W5MU68 W5MU68 PTHR48129:SF1 60S RIBOSOMAL PROTEIN L37A LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000018348.1|UniProtKB=W5NP90 W5NP90 MTERF1 PTHR15437:SF2 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 1, MITOCHONDRIAL nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 LEPOC|Ensembl=ENSLOCG00000014953.1|UniProtKB=W5NCS2 W5NCS2 PTHR44170:SF14 PROTEIN SIDEKICK NEOGENIN cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017454.1|UniProtKB=W5NLQ0 W5NLQ0 PTHR26451:SF847 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012690.1|UniProtKB=W5N4Q6 W5N4Q6 PTHR33768:SF5 MIP11318P SPERM AXONEMAL MAINTENANCE PROTEIN CFAP97D1 LEPOC|Ensembl=ENSLOCG00000017541.1|UniProtKB=W5NLY7 W5NLY7 C3AR1 PTHR24225:SF29 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000013795.1|UniProtKB=W5N8Q3 W5N8Q3 PTHR48153:SF2 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000013647.1|UniProtKB=W5N873 W5N873 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013731.1|UniProtKB=W5N8H6 W5N8H6 SLC41A3 PTHR16228:SF22 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012588.1|UniProtKB=W5N4D8 W5N4D8 CDKN2B PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B protein kinase regulator activity#GO:0019887;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase binding#GO:0019900 negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of cell population proliferation#GO:0008285;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346;regulation of phosphorylation#GO:0042325;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574 LEPOC|Ensembl=ENSLOCG00000017753.1|UniProtKB=W5NMJ8 W5NMJ8 PTHR10494:SF5 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;ossification#GO:0001503;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;osteoblast differentiation#GO:0001649;dorsal/ventral pattern formation#GO:0009953;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003606.1|UniProtKB=W5M7B8 W5M7B8 PTHR10997:SF27 IMPORTIN-7, 8, 11 IMPORTIN-7 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001319.1|UniProtKB=W5LZH3 W5LZH3 PTHR10648:SF4 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000001909.1|UniProtKB=W5M1F6 W5M1F6 PTHR10758:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 COP9 SIGNALOSOME COMPLEX SUBUNIT 3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015282.1|UniProtKB=W5NDU9 W5NDU9 PTHR10782:SF38 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;ubiquitin-like protein ligase activity#GO:0061659;SUMO ligase activity#GO:0061665;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein sumoylation#GO:0016925;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005730.1|UniProtKB=W5MEW6 W5MEW6 PTHR24254:SF10 PROTHROMBIN PROTHROMBIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;platelet activation#GO:0030168;regulation of coagulation#GO:0050818;regulation of response to stress#GO:0080134;regulation of body fluid levels#GO:0050878;wound healing#GO:0042060;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;regulation of response to wounding#GO:1903034;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of wound healing#GO:0061041;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 Blood coagulation#P00011>Prothrombin#P00416;Blood coagulation#P00011>Thrombin#P00414 LEPOC|Ensembl=ENSLOCG00000009533.1|UniProtKB=W5MTE6 W5MTE6 GHRHR PTHR45620:SF14 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017828.1|UniProtKB=W5NMS2 W5NMS2 PTHR28649:SF2 PROTEIN REPRIMO-RELATED PROTEIN REPRIMO LEPOC|Ensembl=ENSLOCG00000000112.1|UniProtKB=W5LVG9 W5LVG9 PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008014.1|UniProtKB=W5MMX9 W5MMX9 PTHR13621:SF2 PROLINE-RICH PROTEIN PRCC PROLINE-RICH PROTEIN PRCC membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008787.1|UniProtKB=W5MQN7 W5MQN7 PTHR45624:SF22 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012442.1|UniProtKB=W5N3V5 W5N3V5 PTHR35453:SF1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013811.1|UniProtKB=W5N8S4 W5N8S4 PTHR24214:SF7 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001966.1|UniProtKB=W5M1M3 W5M1M3 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007667.1|UniProtKB=W5MLP3 W5MLP3 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009112.1|UniProtKB=W5MRV4 W5MRV4 PTHR45961:SF1 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 18 ISOFORM X1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012346.1|UniProtKB=W5N3J5 W5N3J5 PTHR45620:SF22 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011046.1|UniProtKB=W5MYV6 W5MYV6 PTHR10846:SF41 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of signaling#GO:0023051;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;negative regulation of signaling#GO:0023057;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008711.1|UniProtKB=W5MQE6 W5MQE6 PTHR10801:SF0 24-DEHYDROCHOLESTEROL REDUCTASE DELTA(24)-STEROL REDUCTASE reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005393.1|UniProtKB=W5MDP3 W5MDP3 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003648.1|UniProtKB=W5M7H9 W5M7H9 PTHR14493:SF37 UNKEMPT FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE UNKL-RELATED LEPOC|Ensembl=ENSLOCG00000002945.1|UniProtKB=W5M507 W5M507 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005270.1|UniProtKB=W5MDA9 W5MDA9 PTHR23113:SF187 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014432.1|UniProtKB=W5NAV5 W5NAV5 PTHR23402:SF1 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE I cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016396.1|UniProtKB=W5NHZ0 W5NHZ0 PTHR11528:SF79 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein stabilization#GO:0050821;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000013591.1|UniProtKB=W5N802 W5N802 PTHR47050:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 24 TETRATRICOPEPTIDE REPEAT PROTEIN 24-LIKE LEPOC|Ensembl=ENSLOCG00000008906.1|UniProtKB=W5MR36 W5MR36 PTHR13593:SF147 FAMILY NOT NAMED 1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE-LIKE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 LEPOC|Ensembl=ENSLOCG00000014122.1|UniProtKB=W5N9U1 W5N9U1 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000001955.1|UniProtKB=W5M1K1 W5M1K1 P2RY14 PTHR24233:SF3 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 14 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012104.1|UniProtKB=W5N2N7 W5N2N7 PTHR12151:SF4 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER PROTEIN SCO1 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016965.1|UniProtKB=W5NK12 W5NK12 PTHR12894:SF30 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1-LIKE vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagy#GO:0006914;organelle fusion#GO:0048284;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010211.1|UniProtKB=W5MVU8 W5MVU8 PTHR24366:SF75 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 1 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000013100.1|UniProtKB=W5N678 W5N678 OTOP3 PTHR21522:SF36 PROTON CHANNEL OTOP PROTON CHANNEL OTOP3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003706.1|UniProtKB=W5M7P8 W5M7P8 PTHR21472:SF18 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000008422.1|UniProtKB=W5MPD2 W5MPD2 PTHR22461:SF2 SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2-RELATED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011620.1|UniProtKB=W5N0W9 W5N0W9 LRRTM3 PTHR24366:SF150 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015791.1|UniProtKB=W5NFN0 W5NFN0 PTHR19282:SF462 TETRASPANIN TETRASPANIN-12 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009735.1|UniProtKB=W5MU29 W5MU29 PTHR13343:SF21 CREG1 PROTEIN PROTEIN CREG1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000016796.1|UniProtKB=W5NJF1 W5NJF1 PTHR24061:SF506 CALCIUM-SENSING RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A-LIKE PRECURSOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001216.1|UniProtKB=W5LZ17 W5LZ17 PTHR19850:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;GABA-B receptor II signaling#P05731>Gbeta#P05755;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753 LEPOC|Ensembl=ENSLOCG00000006763.1|UniProtKB=W5MII0 W5MII0 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001243.1|UniProtKB=W5LZ54 W5LZ54 PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002590.1|UniProtKB=W5M3U4 W5M3U4 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011169.1|UniProtKB=W5MZB4 W5MZB4 PTHR31570:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002152.1|UniProtKB=W5M2A0 W5M2A0 IDNK PTHR43442:SF3 GLUCONOKINASE-RELATED GLUCONOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015278.1|UniProtKB=W5NDU1 W5NDU1 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015811.1|UniProtKB=W5NFQ7 W5NFQ7 PTHR45885:SF1 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008284.1|UniProtKB=W5MNV1 W5MNV1 PTHR44156:SF6 SUPERNUMERARY LIMBS, ISOFORM B-RELATED DYNEIN ASSEMBLY FACTOR WITH WDR REPEAT DOMAINS 1 LEPOC|Ensembl=ENSLOCG00000005331.1|UniProtKB=W5MDG4 W5MDG4 PTHR46242:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015547.1|UniProtKB=W5NES8 W5NES8 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000697.1|UniProtKB=W5LXB4 W5LXB4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004950.1|UniProtKB=W5MC51 W5MC51 PTHR11616:SF241 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007917.1|UniProtKB=W5MMK6 W5MMK6 PTHR21029:SF12 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 7-BINDING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015950.1|UniProtKB=W5NG81 W5NG81 PTHR23420:SF2 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE 3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010346.1|UniProtKB=W5MWB9 W5MWB9 PTHR15375:SF22 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG A protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle#GO:0045787;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cell cycle process#GO:0090068;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000003213.1|UniProtKB=W5M5Z1 W5M5Z1 PTHR19331:SF471 SCAVENGER RECEPTOR DOMAIN-CONTAINING SRCR DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013960.1|UniProtKB=W5N999 W5N999 PTHR48421:SF1 MYCBP-ASSOCIATED PROTEIN MYCBP-ASSOCIATED PROTEIN LEPOC|Ensembl=ENSLOCG00000008779.1|UniProtKB=W5MQM9 W5MQM9 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004461.1|UniProtKB=W5MAC0 W5MAC0 PTHR16138:SF7 MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL PALMITOYL-PROTEIN THIOESTERASE ABHD10, MITOCHONDRIAL esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000006381.1|UniProtKB=W5MH45 W5MH45 PTHR42757:SF44 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 141 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011815.1|UniProtKB=W5N1M4 W5N1M4 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001390.1|UniProtKB=W5LZM1 W5LZM1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012315.1|UniProtKB=W5N3F1 W5N3F1 RBM20 PTHR15592:SF11 MATRIN 3/NUCLEAR PROTEIN 220-RELATED RNA-BINDING PROTEIN 20 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018077.1|UniProtKB=W5NNG9 W5NNG9 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000004846.1|UniProtKB=W5MBR2 W5MBR2 PTHR13318:SF169 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 9 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000010573.1|UniProtKB=W5MX45 W5MX45 PTHR36871:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 LEPOC|Ensembl=ENSLOCG00000015742.1|UniProtKB=W5NFG9 W5NFG9 CCDC38 PTHR21683:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA AND FLAGELLA ASSOCIATED PROTEIN 100 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015521.1|UniProtKB=W5NEQ3 W5NEQ3 PTHR10166:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;sarcolemma#GO:0042383;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>Ca2+ channel#P01081 LEPOC|Ensembl=ENSLOCG00000003313.1|UniProtKB=W5M6C6 W5M6C6 PTHR45704:SF2 RAS-LIKE FAMILY MEMBER 11 RERG_RAS-LIKE B LEPOC|Ensembl=ENSLOCG00000010074.1|UniProtKB=W5MVB4 W5MVB4 PTHR45726:SF1 LEUKOTRIENE A-4 HYDROLASE AMINOPEPTIDASE B metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloaminopeptidase activity#GO:0070006 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003712.1|UniProtKB=W5M7Q5 W5M7Q5 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009062.1|UniProtKB=W5MRN6 W5MRN6 CARMIL1 PTHR24112:SF39 LEUCINE-RICH REPEAT, ISOFORM F-RELATED F-ACTIN-UNCAPPING PROTEIN LRRC16A regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell leading edge#GO:0031252;lamellipodium#GO:0030027;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009446.1|UniProtKB=W5MT24 W5MT24 PTHR17615:SF8 PROTEIN FAM189A ENDOSOMAL TRANSMEMBRANE EPSIN INTERACTOR 1 LEPOC|Ensembl=ENSLOCG00000016291.1|UniProtKB=W5NHJ6 W5NHJ6 CCDC170 PTHR18863:SF4 TSEC-2-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 170 LEPOC|Ensembl=ENSLOCG00000004295.1|UniProtKB=W5M9S1 W5M9S1 PTHR43194:SF2 HYDROLASE ALPHA/BETA FOLD FAMILY PEROXISOMAL MEMBRANE PROTEIN LPX1 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007106.1|UniProtKB=W5MJP4 W5MJP4 PTHR45970:SF4 AGAP004664-PA HOMEOBOX PROTEIN HOX-D9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004788.1|UniProtKB=W5MBK9 W5MBK9 PTHR46289:SF13 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-RELATED LEPOC|Ensembl=ENSLOCG00000010064.1|UniProtKB=W5MVA2 W5MVA2 PTHR10649:SF17 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000013720.1|UniProtKB=W5N8F7 W5N8F7 PTHR48051:SF48 FAMILY NOT NAMED MULTIFUNCTIONAL ROCO FAMILY SIGNALING REGULATOR 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006630.1|UniProtKB=W5MI01 W5MI01 PTHR13002:SF1 C3ORF1 PROTEIN-RELATED COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014593.1|UniProtKB=W5NBE9 W5NBE9 PTHR22674:SF6 NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009820.1|UniProtKB=W5MUE1 W5MUE1 PTHR48012:SF1 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE OSR1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of metal ion transport#GO:0010959;regulation of lymphocyte migration#GO:2000401;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of transport#GO:0051051;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;regulation of potassium ion transmembrane transport#GO:1901379;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;peptidyl-threonine phosphorylation#GO:0018107;biological regulation#GO:0065007;positive regulation of leukocyte chemotaxis#GO:0002690;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013775.1|UniProtKB=W5N8M8 W5N8M8 PTHR21053:SF2 TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011047.1|UniProtKB=W5MYW9 W5MYW9 PTHR13018:SF21 PROBABLE MEMBRANE PROTEIN DUF221-RELATED CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011809.1|UniProtKB=W5N1L3 W5N1L3 PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE MEMBRANE SUBUNIT K, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014922.1|UniProtKB=W5NCL4 W5NCL4 CCDC33 PTHR21623:SF2 SPERIOLIN-BINDING FACTOR COILED-COIL DOMAIN-CONTAINING PROTEIN 33 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011586.1|UniProtKB=W5N0T3 W5N0T3 PTHR48083:SF13 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 11 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011213.1|UniProtKB=W5MZH2 W5MZH2 PTHR14949:SF53 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 anatomical structure development#GO:0048856;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000006476.1|UniProtKB=W5MHG4 W5MHG4 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005729.1|UniProtKB=W5MEV0 W5MEV0 PTHR11767:SF16 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;GABA-B receptor II signaling#P05731>K channel#P05758;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 LEPOC|Ensembl=ENSLOCG00000005450.1|UniProtKB=W5MDW5 W5MDW5 PTHR22896:SF3 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 2 LEPOC|Ensembl=ENSLOCG00000001476.1|UniProtKB=W5LZZ9 W5LZZ9 SEMA4F PTHR11036:SF72 SEMAPHORIN SEMAPHORIN-4F molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014325.1|UniProtKB=W5NAJ8 W5NAJ8 PTHR11036:SF37 SEMAPHORIN SEMAPHORIN-3B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000744.1|UniProtKB=W5LXJ4 W5LXJ4 PTHR22826:SF104 RHO GUANINE EXCHANGE FACTOR-RELATED TRIPLE FUNCTIONAL DOMAIN PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010430.1|UniProtKB=W5MWQ2 W5MWQ2 PTHR46877:SF10 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 6 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003725.1|UniProtKB=W5M7S1 W5M7S1 KLHL34 PTHR45632:SF8 LD33804P KELCH-LIKE PROTEIN 34 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016268.1|UniProtKB=W5NHF7 W5NHF7 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 LEPOC|Ensembl=ENSLOCG00000007254.1|UniProtKB=W5MK69 W5MK69 PTHR24409:SF319 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 438 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011330.1|UniProtKB=W5MZW6 W5MZW6 PTHR11385:SF14 SERUM ALBUMIN-RELATED AFAMIN small molecule binding#GO:0036094;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002886.1|UniProtKB=W5M4Y3 W5M4Y3 PTHR18896:SF198 PHOSPHOLIPASE D PHOSPHOLIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;lipid catabolic process#GO:0016042;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate catabolic process#GO:0046434;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;phospholipid catabolic process#GO:0009395;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular membrane-bounded organelle#GO:0043231;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000015749.1|UniProtKB=W5NFH9 W5NFH9 METAP2 PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011359.1|UniProtKB=W5N001 W5N001 PTHR47992:SF119 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1K, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014249.1|UniProtKB=W5NA84 W5NA84 PTHR46923:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 sperm capacitation#GO:0048240;germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cilium-dependent cell motility#GO:0060285;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;CatSper complex#GO:0036128;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005354.1|UniProtKB=W5MDJ9 W5MDJ9 PTHR43570:SF9 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000008455.1|UniProtKB=W5MPH8 W5MPH8 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003644.1|UniProtKB=W5M7H2 W5M7H2 PTHR11848:SF166 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 11 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000001637.1|UniProtKB=W5M0I2 W5M0I2 PTHR47977:SF26 RAS-RELATED PROTEIN RAB RAB1B, MEMBER RAS ONCO FAMILY GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014329.1|UniProtKB=W5NAI3 W5NAI3 PTHR45711:SF7 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 5 voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;Golgi apparatus#GO:0005794;cell junction#GO:0030054;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013273.1|UniProtKB=W5N6W9 W5N6W9 PTHR13950:SF13 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 2 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004556.1|UniProtKB=W5MAN6 W5MAN6 PTHR24232:SF100 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 35, TANDEM DUPLICATE 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012097.1|UniProtKB=W5N2M5 W5N2M5 PTHR21093:SF2 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1C LEPOC|Ensembl=ENSLOCG00000013573.1|UniProtKB=W5N7X5 W5N7X5 PTHR46231:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016143.1|UniProtKB=W5NGY2 W5NGY2 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000003574.1|UniProtKB=W5M777 W5M777 PTHR10036:SF7 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 1 signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 LEPOC|Ensembl=ENSLOCG00000012762.1|UniProtKB=W5N507 W5N507 PTHR24351:SF200 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Ras Pathway#P04393>AKT#P04570;Angiogenesis#P00005>Akt#P00223;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;p53 pathway#P00059>Akt#P01486;Interleukin signaling pathway#P00036>PKB#P00973;Huntington disease#P00029>Akt#P00805;Apoptosis signaling pathway#P00006>AKT#P00260;p53 pathway by glucose deprivation#P04397>Akt#P04641;FGF signaling pathway#P00021>Akt#P00632;VEGF signaling pathway#P00056>Akt/PKB#P01408;p53 pathway feedback loops 2#P04398>AKT#P04665;EGF receptor signaling pathway#P00018>Akt#P00551;Hypoxia response via HIF activation#P00030>AKT#P00819;T cell activation#P00053>Akt#P01332;PI3 kinase pathway#P00048>PKB#P01179;FAS signaling pathway#P00020>ASK1#P00614;Endothelin signaling pathway#P00019>Akt#P00589 LEPOC|Ensembl=ENSLOCG00000009881.1|UniProtKB=W5MUL8 W5MUL8 PTHR23001:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014149.1|UniProtKB=W5N9X0 W5N9X0 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014782.1|UniProtKB=W5NC48 W5NC48 PTHR48015:SF12 SERINE/THREONINE-PROTEIN KINASE TAO NIK RELATED KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001104.1|UniProtKB=W5LYQ8 W5LYQ8 PTHR11640:SF14 NEPHRIN KIN OF IRRE-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014484.1|UniProtKB=W5NB18 W5NB18 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001721.1|UniProtKB=W5M0U2 W5M0U2 PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B LEPOC|Ensembl=ENSLOCG00000014237.1|UniProtKB=W5NA72 W5NA72 PTHR13244:SF7 ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013183.1|UniProtKB=W5N6I9 W5N6I9 PTHR18947:SF31 HOOK PROTEINS PROTEIN DAPLE cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002895.1|UniProtKB=W5M4U7 W5M4U7 NCKAP5 PTHR21740:SF0 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule depolymerization#GO:0007019;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009463.1|UniProtKB=W5MT45 W5MT45 PTHR11913:SF53 COFILIN-RELATED COFILIN 2 (MUSCLE)-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;protein-containing complex disassembly#GO:0032984;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament depolymerization#GO:0030042 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000009000.1|UniProtKB=W5MRF4 W5MRF4 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000014623.1|UniProtKB=W5NBJ2 W5NBJ2 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000002029.1|UniProtKB=W5M1V0 W5M1V0 MAP2K3 PTHR48013:SF21 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p38 MAPK pathway#P05918>MKK3#P06036;Oxidative stress response#P00046>MKK3/6#P01121;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;FGF signaling pathway#P00021>MKK3,6#P00625;Toll receptor signaling pathway#P00054>MKK3#P01367;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Apoptosis signaling pathway#P00006>MKK3#P00314;Ras Pathway#P04393>MKK3/6#P04568;Integrin signalling pathway#P00034>MEK#P00925;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 LEPOC|Ensembl=ENSLOCG00000002293.1|UniProtKB=W5M2V6 W5M2V6 PTHR12995:SF2 FI21814P1 TRANSMEMBRANE PROTEIN 39B cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008003.1|UniProtKB=W5MMW3 W5MMW3 PTHR24366:SF70 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS RETICULON 4 RECEPTOR cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000017398.1|UniProtKB=W5NLJ4 W5NLJ4 PTHR46880:SF8 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE KIAA1586 LEPOC|Ensembl=ENSLOCG00000011277.1|UniProtKB=W5MZQ2 W5MZQ2 H2AZ1 PTHR23430:SF47 HISTONE H2A HISTONE H2A.Z nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011001.1|UniProtKB=W5MYN4 W5MYN4 PTHR11759:SF1 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 40S RIBOSOMAL PROTEIN S14 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011137.1|UniProtKB=W5MZ72 W5MZ72 CAMK2A PTHR24347:SF384 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 LEPOC|Ensembl=ENSLOCG00000003947.1|UniProtKB=W5M8L6 W5M8L6 PTHR14191:SF20 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF4 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012240.1|UniProtKB=W5N352 W5N352 IMPA1 PTHR20854:SF44 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;organic hydroxy compound metabolic process#GO:1901615;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;signaling#GO:0023052;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006087.1|UniProtKB=W5MG77 W5MG77 PTHR10480:SF1 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG A syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;transport#GO:0006810;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;establishment of organelle localization#GO:0051656;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;vesicle localization#GO:0051648;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;synaptic transmission, glutamatergic#GO:0035249;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;neuromuscular junction#GO:0031594;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002764.1|UniProtKB=W5M4F0 W5M4F0 PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;double-stranded RNA binding#GO:0003725 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000000690.1|UniProtKB=W5LXA6 W5LXA6 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000009944.1|UniProtKB=W5MUV4 W5MUV4 PTHR10556:SF31 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001449.1|UniProtKB=W5LZV8 W5LZV8 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006778.1|UniProtKB=W5MIH6 W5MIH6 PTHR11955:SF97 FATTY ACID BINDING PROTEIN RETINOID-BINDING PROTEIN 7 fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000000880.1|UniProtKB=W5LXW9 W5LXW9 PTHR13962:SF26 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000002998.1|UniProtKB=W5M582 W5M582 PKD1 PTHR46730:SF3 POLYCYSTIN-1 POLYCYSTIN-1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000486.1|UniProtKB=W5LWS6 W5LWS6 PTHR24320:SF282 RETINOL DEHYDROGENASE WW DOMAIN-CONTAINING OXIDOREDUCTASE dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015142.1|UniProtKB=W5NDC8 W5NDC8 PTHR48034:SF18 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X CHROMOSOME nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010674.1|UniProtKB=W5MXG5 W5MXG5 PTHR46272:SF5 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016500.1|UniProtKB=W5NIC2 W5NIC2 PTHR16021:SF25 MANSC DOMAIN CONTAINING PROTEIN 1 MANSC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015607.1|UniProtKB=W5NF05 W5NF05 CPA1 PTHR11705:SF94 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A1 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016505.1|UniProtKB=W5NIC8 W5NIC8 PTHR17223:SF0 PARATHYROID HORMONE-RELATED PARATHYROID HORMONE-RELATED PROTEIN peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000009158.1|UniProtKB=W5MS16 W5MS16 PTHR35971:SF5 SI:DKEY-31G6.6 OBSCURIN LIKE CYTOSKELETAL ADAPTOR 1 LEPOC|Ensembl=ENSLOCG00000003402.1|UniProtKB=W5M6N3 W5M6N3 PTHR13131:SF5 CYSTINOSIN CYSTINOSIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;L-amino acid transport#GO:0015807;establishment of localization#GO:0051234;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011462.1|UniProtKB=W5N0C3 W5N0C3 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;kinase binding#GO:0019900 macroautophagy#GO:0016236;mitophagy#GO:0000423;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011761.1|UniProtKB=W5N1F3 W5N1F3 PTHR10903:SF170 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017400.1|UniProtKB=W5NLJ6 W5NLJ6 PTHR26451:SF928 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 148-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017932.1|UniProtKB=W5NN26 W5NN26 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009886.1|UniProtKB=W5MUM2 W5MUM2 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000004287.1|UniProtKB=W5M9R5 W5M9R5 PTHR14215:SF3 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1-LIKE cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organelle organization#GO:0006996;generation of precursor metabolites and energy#GO:0006091;organelle fission#GO:0048285;cellular metabolic process#GO:0044237;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial fission#GO:0000266;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012406.1|UniProtKB=W5N3R4 W5N3R4 PTHR47977:SF58 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN-LIKE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010298.1|UniProtKB=W5MW51 W5MW51 FAM124A PTHR14715:SF4 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124A LEPOC|Ensembl=ENSLOCG00000002139.1|UniProtKB=W5M287 W5M287 PTHR20854:SF29 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 2 inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;organic hydroxy compound metabolic process#GO:1901615;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;signaling#GO:0023052;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002165.1|UniProtKB=W5M2B7 W5M2B7 PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012912.1|UniProtKB=W5N5J2 W5N5J2 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;endoplasmic reticulum tubular network organization#GO:0071786;membrane organization#GO:0061024;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016566.1|UniProtKB=W5NIK1 W5NIK1 PTHR24299:SF11 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016842.1|UniProtKB=W5NJK7 W5NJK7 PTHR22883:SF28 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC14 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002393.1|UniProtKB=W5M3B8 W5M3B8 PTHR11199:SF2 STROMAL ANTIGEN COHESIN SUBUNIT SA protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cohesin complex#GO:0008278;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006059.1|UniProtKB=W5MG14 W5MG14 PTHR11680:SF28 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 LEPOC|Ensembl=ENSLOCG00000016575.1|UniProtKB=W5NIL7 W5NIL7 PTHR11818:SF2 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013398.1|UniProtKB=W5N7A5 W5N7A5 PTHR23268:SF124 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007747.1|UniProtKB=W5MM00 W5MM00 PTHR10201:SF138 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-24 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000003011.1|UniProtKB=W5M5A4 W5M5A4 PTHR46654:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010217.1|UniProtKB=W5MVU9 W5MVU9 PTHR46762:SF1 NUCLEOREDOXIN-LIKE PROTEIN 2 NUCLEOREDOXIN-LIKE PROTEIN 2 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015668.1|UniProtKB=W5NF78 W5NF78 PTHR23231:SF17 GERM CELL-LESS PROTEIN BTB DOMAIN-CONTAINING PROTEIN ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013269.1|UniProtKB=W5N6U6 W5N6U6 PTHR10574:SF378 NETRIN/LAMININ-RELATED NETRIN-1 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 LEPOC|Ensembl=ENSLOCG00000003311.1|UniProtKB=W5M6B8 W5M6B8 PTHR11049:SF1 ACYL COENZYME A THIOESTER HYDROLASE ACYL-COENZYME A THIOESTERASE 11 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000016682.1|UniProtKB=W5NJ01 W5NJ01 PTHR12444:SF4 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG B protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012430.1|UniProtKB=W5N3U2 W5N3U2 SHLD2 PTHR14495:SF2 SHIELDIN COMPLEX SUBUNIT 2 SHIELDIN COMPLEX SUBUNIT 2 regulation of double-strand break repair#GO:2000779;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular response to stress#GO:0080135;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007330.1|UniProtKB=W5MKG5 W5MKG5 PTHR21713:SF3 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017604.1|UniProtKB=W5NM50 W5NM50 PTHR24031:SF421 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX28-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010367.1|UniProtKB=W5MWE4 W5MWE4 SYNPR PTHR10306:SF16 SYNAPTOPHYSIN SYNAPTOPORIN synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002307.1|UniProtKB=W5M2T8 W5M2T8 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001466.1|UniProtKB=W5LZX4 W5LZX4 PTHR19957:SF84 SYNTAXIN SYNTAXIN-1A molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;export from cell#GO:0140352;secretion by cell#GO:0032940;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000013639.1|UniProtKB=W5N878 W5N878 PTHR24356:SF193 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ALPHA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PKC#P00565;CCKR signaling map#P06959>PKCalpha#P07095;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PKC#P05942;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;PDGF signaling pathway#P00047>PKC#P01150;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 LEPOC|Ensembl=ENSLOCG00000017284.1|UniProtKB=W5NL72 W5NL72 PTHR15215:SF1 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007759.1|UniProtKB=W5MM13 W5MM13 PTHR16477:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 COILED-COIL DOMAIN-CONTAINING PROTEIN 106-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007717.1|UniProtKB=W5MLV7 W5MLV7 PTHR19818:SF167 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003225.1|UniProtKB=W5M629 W5M629 PTHR23138:SF142 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3B-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001866.1|UniProtKB=W5M1A1 W5M1A1 PTHR28052:SF1 UPF0545 PROTEIN C22ORF39 UPF0545 PROTEIN C22ORF39 LEPOC|Ensembl=ENSLOCG00000016720.1|UniProtKB=W5NJ54 W5NJ54 PTHR19375:SF438 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 14 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000002940.1|UniProtKB=W5M503 W5M503 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006189.1|UniProtKB=W5MGH0 W5MGH0 PTHR10671:SF32 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003282.1|UniProtKB=W5M671 W5M671 PTHR12015:SF203 SMALL INDUCIBLE CYTOKINE A CHEMOKINE INTERLEUKIN-8-LIKE DOMAIN-CONTAINING PROTEIN cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010918.1|UniProtKB=W5MYF8 W5MYF8 PTHR24223:SF405 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 3 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015199.1|UniProtKB=W5NDJ4 W5NDJ4 PTHR45899:SF5 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1-LIKE nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002942.1|UniProtKB=W5M513 W5M513 PTHR15592:SF17 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006834.1|UniProtKB=W5MIQ4 W5MIQ4 PTHR15739:SF2 ZINC FINGER PROTEIN PROTEIN ZNF365 cellular aromatic compound metabolic process#GO:0006725;regulation of double-strand break repair#GO:2000779;telomere organization#GO:0032200;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;regulation of cellular component organization#GO:0051128;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of double-strand break repair via homologous recombination#GO:0010569;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;chromosome organization#GO:0051276;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000009673.1|UniProtKB=W5MTV9 W5MTV9 PTHR46791:SF13 EXPRESSED PROTEIN CLR5 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009910.1|UniProtKB=W5MUR0 W5MUR0 PTHR24060:SF23 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000009204.1|UniProtKB=W5MS77 W5MS77 PTHR46780:SF4 PROTEIN EVA-1 PROTEIN EVA-1 HOMOLOG C heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000009409.1|UniProtKB=W5MSX2 W5MSX2 ACKR2 PTHR10489:SF942 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 2 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017997.1|UniProtKB=W5NN89 W5NN89 PTHR24034:SF43 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488;transforming growth factor beta binding#GO:0050431;cytokine binding#GO:0019955 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000008632.1|UniProtKB=W5MQ36 W5MQ36 PTHR10682:SF9 POLY A POLYMERASE POLY(A) POLYMERASE ALPHA adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001352.1|UniProtKB=W5LZL5 W5LZL5 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005185.1|UniProtKB=W5MCY4 W5MCY4 PTHR24342:SF5 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004497.1|UniProtKB=W5MAG7 W5MAG7 PTHR15427:SF21 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q AND TUMOR NECROSIS FACTOR-RELATED PROTEIN 9A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013226.1|UniProtKB=W5N6N6 W5N6N6 PTHR24034:SF107 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003171.1|UniProtKB=W5M5V1 W5M5V1 PTHR23024:SF603 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 4 deacetylase#PC00087;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011676.1|UniProtKB=W5N145 W5N145 PTHR24092:SF84 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VD ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017710.1|UniProtKB=W5NMF6 W5NMF6 PTHR24299:SF4 CYTOCHROME P450 FAMILY 1 CYP1C2 PROTEIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006238.1|UniProtKB=W5MGM2 W5MGM2 PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;ribosome biogenesis#GO:0042254;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;protein-containing complex localization#GO:0031503;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011054.1|UniProtKB=W5MYW1 W5MYW1 PTHR12829:SF4 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000001178.1|UniProtKB=W5LYW7 W5LYW7 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000014462.1|UniProtKB=W5NB03 W5NB03 PTHR11533:SF259 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005809.1|UniProtKB=W5MF61 W5MF61 PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000010897.1|UniProtKB=W5MYA1 W5MYA1 PTHR11394:SF72 TASTE RECEPTOR TYPE 2 OLFACTORY RECEPTOR CLASS A-LIKE PROTEIN 4 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001812.1|UniProtKB=W5M139 W5M139 PTHR31937:SF2 TRANSMEMBRANE PROTEIN 163 TRANSMEMBRANE PROTEIN 163 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004436.1|UniProtKB=W5MA93 W5MA93 PTHR22443:SF14 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000002276.1|UniProtKB=W5M2Q0 W5M2Q0 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016443.1|UniProtKB=W5NI50 W5NI50 PTHR11848:SF300 TGF-BETA FAMILY CVG1 PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000002556.1|UniProtKB=W5M3S0 W5M3S0 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN 12 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008771.1|UniProtKB=W5MQM5 W5MQM5 ATE1 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004625.1|UniProtKB=W5MB54 W5MB54 PTHR24023:SF387 COLLAGEN ALPHA COLLAGEN ALPHA-1(V) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000001520.1|UniProtKB=W5M024 W5M024 PTHR47743:SF1 KIAA1210 / KIAA1211 FAMILY MEMBER CRACD-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000013080.1|UniProtKB=W5N652 W5N652 PTHR11551:SF3 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 p53 pathway#P00059>IGF-BP3#G04691 LEPOC|Ensembl=ENSLOCG00000012741.1|UniProtKB=W5N4X5 W5N4X5 PTHR46121:SF2 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STAR-RELATED LIPID TRANSFER PROTEIN 3 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;sterol transport#GO:0015918;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;lipid localization#GO:0010876;establishment of organelle localization#GO:0051656 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;organelle membrane contact site#GO:0044232;vesicle#GO:0031982;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;lysosome#GO:0005764;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuolar membrane#GO:0005774;organelle subcompartment#GO:0031984;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000000997.1|UniProtKB=W5LYB6 W5LYB6 PTHR15141:SF75 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013712.1|UniProtKB=W5N8F9 W5N8F9 CAMTA2 PTHR23335:SF9 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004548.1|UniProtKB=W5MAM9 W5MAM9 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5-RELATED cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000004111.1|UniProtKB=W5M973 W5M973 MYO9B PTHR46184:SF2 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXB microfilament motor activity#GO:0000146;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;anion binding#GO:0043168;actin binding#GO:0003779;ATP binding#GO:0005524 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;actin filament-based movement#GO:0030048;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;ruffle#GO:0001726;cytoskeleton#GO:0005856;cell projection#GO:0042995 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000006504.1|UniProtKB=W5MHM2 W5MHM2 PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014181.1|UniProtKB=W5NA09 W5NA09 PTHR16148:SF11 NF-KAPPA-B-REPRESSING FACTOR-RELATED CDKN2A-INTERACTING PROTEIN membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013747.1|UniProtKB=W5N8J5 W5N8J5 PTHR31158:SF1 DUAL OXIDASE 2 DOXA1 FACTOR-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017192.1|UniProtKB=W5NKT8 W5NKT8 PTHR16517:SF1 TUBBY-RELATED WD REPEAT-CONTAINING PROTEIN 35 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006918.1|UniProtKB=W5MJ26 W5MJ26 PTHR12215:SF10 PHOSPHOPANTETHEINE TRANSFERASE L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;lysine biosynthetic process#GO:0009085;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016161.1|UniProtKB=W5NH04 W5NH04 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003762.1|UniProtKB=W5M7X2 W5M7X2 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014626.1|UniProtKB=W5NBJ4 W5NBJ4 PTHR11242:SF13 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9B chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011611.1|UniProtKB=W5N0W3 W5N0W3 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004563.1|UniProtKB=W5MAV4 W5MAV4 PTHR45615:SF50 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-16 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000002868.1|UniProtKB=W5M4R0 W5M4R0 PTHR36681:SF3 NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3 NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3 LEPOC|Ensembl=ENSLOCG00000012682.1|UniProtKB=W5N4P6 W5N4P6 PTHR11586:SF33 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003698.1|UniProtKB=W5M7P5 W5M7P5 SCARF2 PTHR24043:SF5 SCAVENGER RECEPTOR CLASS F SCAVENGER RECEPTOR CLASS F MEMBER 2 cargo receptor activity#GO:0038024 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001075.1|UniProtKB=W5LYK3 W5LYK3 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001858.1|UniProtKB=W5M196 W5M196 PTHR18763:SF0 WD-REPEAT PROTEIN 18 WD REPEAT-CONTAINING PROTEIN 18 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;DNA-templated DNA replication#GO:0006261;ribosome biogenesis#GO:0042254;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;endoribonuclease complex#GO:1902555;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear pre-replicative complex#GO:0005656;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010212.1|UniProtKB=W5MVU2 W5MVU2 PTHR46593:SF1 TRANSMEMBRANE PROTEIN 64 TRANSMEMBRANE PROTEIN 64 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;regulation of cytosolic calcium ion concentration#GO:0051480;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012141.1|UniProtKB=W5N2S4 W5N2S4 PTHR45712:SF8 AGAP008170-PA PROLARGIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014267.1|UniProtKB=W5NAB0 W5NAB0 PTHR24261:SF12 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;peptidase activity#GO:0008233;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016180.1|UniProtKB=W5NH34 W5NH34 PTHR24070:SF393 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1B-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;small GTPase-mediated signal transduction#GO:0007264;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;cellular response to nitrogen compound#GO:1901699;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of exocytosis#GO:0017157;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#P06803;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06881;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06668;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 LEPOC|Ensembl=ENSLOCG00000000949.1|UniProtKB=W5LY82 W5LY82 PTHR11566:SF39 DYNAMIN DYNAMIN-1-LIKE PROTEIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle localization#GO:0051640;apoptotic mitochondrial changes#GO:0008637;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;apoptotic process#GO:0006915;cell death#GO:0008219;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;peroxisome organization#GO:0007031;import into cell#GO:0098657;mitochondrial fission#GO:0000266 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005972.1|UniProtKB=W5MFS3 W5MFS3 PTHR24028:SF310 CADHERIN-87A NEURAL-CADHERIN-LIKE PROTEIN cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000004018.1|UniProtKB=W5M8T8 W5M8T8 PTHR12757:SF2 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008738.1|UniProtKB=W5MQH4 W5MQH4 PTHR46096:SF1 PERFORIN-1 PERFORIN 1.5 wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;cell recognition#GO:0008037;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;T cell mediated immunity#GO:0002456;cell killing#GO:0001906;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;defense response to symbiont#GO:0140546;cell-cell recognition#GO:0009988;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation#GO:0001775;leukocyte mediated cytotoxicity#GO:0001909;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;adaptive immune response#GO:0002250;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;multicellular organismal process#GO:0032501;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;leukocyte activation#GO:0045321 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005534.1|UniProtKB=W5ME78 W5ME78 PTHR11601:SF62 CYSTEINE DESULFURYLASE FAMILY MEMBER SELENOCYSTEINE LYASE lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000011705.1|UniProtKB=W5N182 W5N182 PTHR23423:SF28 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184B localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010507.1|UniProtKB=W5MWW9 W5MWW9 PTHR23351:SF4 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN C-FOS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Interleukin signaling pathway#P00036>c-fos#P00967;CCKR signaling map#P06959>FOS#P07035;PDGF signaling pathway#P00047>c-fos#P01145;Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06680;Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06894;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709;Angiogenesis#P00005>c-Fos#P00235;Apoptosis signaling pathway#P00006>Fos#P00317;CCKR signaling map#P06959>FOS#G06973;CCKR signaling map#P06959>FOS#G07266;Huntington disease#P00029>Fos protein#P00801;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>c-fos#P00884;B cell activation#P00010>fos#P00380;T cell activation#P00053>fos#P01309 LEPOC|Ensembl=ENSLOCG00000016728.1|UniProtKB=W5NJ61 W5NJ61 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000015940.1|UniProtKB=W5NG66 W5NG66 MDFIC PTHR15304:SF0 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012657.1|UniProtKB=W5N4M1 W5N4M1 PTHR28658:SF3 TRANSMEMBRANE PROTEIN 180 TRANSMEMBRANE PROTEIN 180 LEPOC|Ensembl=ENSLOCG00000013064.1|UniProtKB=W5N631 W5N631 PTHR11767:SF24 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 16 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018268.1|UniProtKB=W5NP10 W5NP10 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015007.1|UniProtKB=W5NCW7 W5NCW7 PTHR23511:SF34 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003321.1|UniProtKB=W5M6B9 W5M6B9 PTHR17490:SF10 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016299.1|UniProtKB=W5NHK6 W5NHK6 KCNK12 PTHR11003:SF11 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 12 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006417.1|UniProtKB=W5MH99 W5MH99 PTHR10570:SF9 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;lymphocyte activation#GO:0046649;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;T cell differentiation#GO:0030217;cell activation#GO:0001775;regulation of biological process#GO:0050789;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;cell differentiation#GO:0030154;lymphocyte differentiation#GO:0030098;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;signaling#GO:0023052;leukocyte activation#GO:0045321 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 eta#P01302 LEPOC|Ensembl=ENSLOCG00000013008.1|UniProtKB=W5N5W4 W5N5W4 PTHR11949:SF6 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000013892.1|UniProtKB=W5N921 W5N921 PTHR13703:SF28 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;molecular function regulator activity#GO:0098772;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular function inhibitor activity#GO:0140678 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>I-SMAD#G01548;TGF-beta signaling pathway#P00052>I-Smads#P01289 LEPOC|Ensembl=ENSLOCG00000005631.1|UniProtKB=W5MEI5 W5MEI5 PTHR45704:SF8 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE ESTROGEN-REGULATED GROWTH INHIBITOR LEPOC|Ensembl=ENSLOCG00000008634.1|UniProtKB=W5MQ35 W5MQ35 PTHR23216:SF1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002682.1|UniProtKB=W5M437 W5M437 PTHR37359:SF1 TRANSMEMBRANE PROTEIN 253 TRANSMEMBRANE PROTEIN 253 LEPOC|Ensembl=ENSLOCG00000004512.1|UniProtKB=W5MAJ3 W5MAJ3 PTHR44468:SF3 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 homotypic cell-cell adhesion#GO:0034109;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basal plasma membrane#GO:0009925;intercalated disc#GO:0014704;tight junction#GO:0070160;plasma membrane region#GO:0098590;cell-cell contact zone#GO:0044291;basal part of cell#GO:0045178;apical junction complex#GO:0043296;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014069.1|UniProtKB=W5N9M9 W5N9M9 PTHR15549:SF30 PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR MID2 DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002480.1|UniProtKB=W5M3F0 W5M3F0 PTHR12958:SF4 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM1 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;erythrocyte differentiation#GO:0030218;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008080.1|UniProtKB=W5MN53 W5MN53 CCDC152 PTHR35253:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 LEPOC|Ensembl=ENSLOCG00000002955.1|UniProtKB=W5M521 W5M521 SLC35F5 PTHR23051:SF0 SOLUTE CARRIER FAMILY 35, MEMBER F5 SOLUTE CARRIER FAMILY 35 MEMBER F5 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008053.1|UniProtKB=W5MN21 W5MN21 PTHR28567:SF1 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53B cellular localization#GO:0051641;macromolecule localization#GO:0033036;positive regulation of signal transduction#GO:0009967;transport#GO:0006810;regulation of signaling#GO:0023051;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;positive regulation of Wnt signaling pathway#GO:0030177;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;regulation of cell communication#GO:0010646;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014520.1|UniProtKB=W5NB62 W5NB62 PTHR15919:SF1 DAPPER-RELATED DAPPER HOMOLOG 3 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015184.1|UniProtKB=W5NDH4 W5NDH4 PTHR24045:SF0 FAMILY NOT NAMED N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA LEPOC|Ensembl=ENSLOCG00000003129.1|UniProtKB=W5M5M6 W5M5M6 PTHR24247:SF273 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004501.1|UniProtKB=W5MAH0 W5MAH0 PTHR24404:SF33 ZINC FINGER PROTEIN ZINC FINGER PROTEIN HELIOS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003453.1|UniProtKB=W5M6T4 W5M6T4 PTHR47979:SF5 DRAB11-RELATED RAS-RELATED PROTEIN RAB-42 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000012758.1|UniProtKB=W5N502 W5N502 PTHR21355:SF0 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002395.1|UniProtKB=W5M352 W5M352 PTHR12626:SF4 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011027.1|UniProtKB=W5MYS3 W5MYS3 PTHR17408:SF7 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;mRNA 3'-end processing#GO:0031124;organic substance transport#GO:0071702;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound transport#GO:0015931;mRNA processing#GO:0006397 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009898.1|UniProtKB=W5MUP1 W5MUP1 PTHR24073:SF572 DRAB5-RELATED RAS-RELATED PROTEIN RAB-28 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000227.1|UniProtKB=W5LVV2 W5LVV2 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005294.1|UniProtKB=W5MDC2 W5MDC2 PTHR18887:SF4 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1-LIKE LEPOC|Ensembl=ENSLOCG00000004852.1|UniProtKB=W5MBS1 W5MBS1 PTHR11849:SF275 ETS FLI-1 PROTO-ONCOGENE, ETS TRANSCRIPTION FACTOR B ISOFORM X1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001874.1|UniProtKB=W5M1C3 W5M1C3 PTHR10794:SF50 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHOLIPASE ABHD3 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007588.1|UniProtKB=W5MLF1 W5MLF1 ARHGEF25 PTHR22826:SF210 RHO GUANINE EXCHANGE FACTOR-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR (GEF) 25B-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009113.1|UniProtKB=W5MRV5 W5MRV5 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011986.1|UniProtKB=W5N281 W5N281 PTHR23210:SF26 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of chromosome organization#GO:0033044;positive regulation of organelle organization#GO:0010638;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular component biogenesis#GO:0044087;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of chromatin organization#GO:1902275;positive regulation of cellular component biogenesis#GO:0044089;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000017814.1|UniProtKB=W5NMQ9 W5NMQ9 PTHR19290:SF52 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 22 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004122.1|UniProtKB=W5M966 W5M966 PTHR43671:SF98 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK11 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012055.1|UniProtKB=W5N2G9 W5N2G9 HDAC3 PTHR10625:SF36 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 3 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Wnt signaling pathway#P00057>Histone deacetylase#P01472 LEPOC|Ensembl=ENSLOCG00000002718.1|UniProtKB=W5M496 W5M496 UBP1 PTHR11037:SF13 TRANSCRIPTION FACTOR CP2 UPSTREAM-BINDING PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016875.1|UniProtKB=W5NJQ6 W5NJQ6 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA duplex unwinding#GO:0032508;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;DNA geometric change#GO:0032392 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007780.1|UniProtKB=W5MM37 W5MM37 PTHR24113:SF15 RAN GTPASE-ACTIVATING PROTEIN 1 NACHT DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 cellular localization#GO:0051641;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;transport#GO:0006810;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;localization#GO:0051179;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of hydrolase activity#GO:0051336;intracellular transport#GO:0046907;nuclear transport#GO:0051169 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004067.1|UniProtKB=W5M907 W5M907 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG LEPOC|Ensembl=ENSLOCG00000007803.1|UniProtKB=W5MM58 W5MM58 PTHR11848:SF78 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 15 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000018084.1|UniProtKB=W5NNH6 W5NNH6 PTHR11937:SF566 ACTIN ACTIN, BETA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000013911.1|UniProtKB=W5N939 W5N939 PTHR34605:SF3 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN P CELL-TYPE AGGLUTINATION PROTEIN MAP4-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000001586.1|UniProtKB=W5M0B5 W5M0B5 PTHR13814:SF15 FETUIN SI:CH211-262H13.5 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000003923.1|UniProtKB=W5M8I1 W5M8I1 PTHR10543:SF86 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 15,15'-MONOOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;isoprenoid catabolic process#GO:0008300;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;terpenoid metabolic process#GO:0006721 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017482.1|UniProtKB=W5NLS8 W5NLS8 PTHR47981:SF17 RAB FAMILY RAS-RELATED PROTEIN RAB-9B lysosome organization#GO:0007040;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000007569.1|UniProtKB=W5MLC4 W5MLC4 STK4 PTHR48015:SF32 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010466.1|UniProtKB=W5MWS4 W5MWS4 GRXCR2 PTHR46926:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014164.1|UniProtKB=W5N9Z0 W5N9Z0 PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000010934.1|UniProtKB=W5MYG1 W5MYG1 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;branched-chain amino acid metabolic process#GO:0009081;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 LEPOC|Ensembl=ENSLOCG00000010124.1|UniProtKB=W5MVI0 W5MVI0 PTHR13411:SF6 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteolysis#GO:0045862;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000011617.1|UniProtKB=W5N0W4 W5N0W4 PTHR31516:SF17 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015177.1|UniProtKB=W5NDG6 W5NDG6 PTHR32121:SF0 PCNA-INTERACTING PARTNER PCNA-INTERACTING PARTNER negative regulation of cellular metabolic process#GO:0031324;regulation of double-strand break repair#GO:2000779;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;negative regulation of DNA repair#GO:0045738;regulation of response to stress#GO:0080134;negative regulation of metabolic process#GO:0009892;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular response to stress#GO:0080135;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of double-strand break repair via homologous recombination#GO:2000042;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA recombination#GO:0000018;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015163.1|UniProtKB=W5NDF3 W5NDF3 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014656.1|UniProtKB=W5NBM7 W5NBM7 PTHR31594:SF15 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN VERRUCOTOXIN SUBUNIT BETA ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000010155.1|UniProtKB=W5MVM6 W5MVM6 PTHR14399:SF3 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000014233.1|UniProtKB=W5NA68 W5NA68 PTHR12499:SF0 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010628.1|UniProtKB=W5MXA6 W5MXA6 PTHR11515:SF5 GLYCOPROTEIN HORMONE BETA CHAIN THYROTROPIN SUBUNIT BETA regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586 LEPOC|Ensembl=ENSLOCG00000004319.1|UniProtKB=W5M9U8 W5M9U8 PTHR28546:SF1 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURON-SPECIFIC VESICULAR PROTEIN CALCYON protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;transport#GO:0006810;protein-containing complex assembly#GO:0065003;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000755.1|UniProtKB=W5LXH9 W5LXH9 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008335.1|UniProtKB=W5MP17 W5MP17 PTHR10694:SF113 LYSINE-SPECIFIC DEMETHYLASE PROTEIN JUMONJI histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014168.1|UniProtKB=W5N9Z4 W5N9Z4 PTHR24056:SF503 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010018.1|UniProtKB=W5MV41 W5MV41 PTHR21737:SF21 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 MARVEL DOMAIN CONTAINING 3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006383.1|UniProtKB=W5MH57 W5MH57 PTHR48012:SF9 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 25 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007792.1|UniProtKB=W5MM63 W5MM63 PTHR43836:SF1 CATECHOL O-METHYLTRANSFERASE 1-RELATED TRANSMEMBRANE O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;catecholamine metabolic process#GO:0006584;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003632.1|UniProtKB=W5M7E9 W5M7E9 PTHR12460:SF2 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1A basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000006410.1|UniProtKB=W5MH85 W5MH85 PTHR22950:SF192 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 7 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;amide transmembrane transporter activity#GO:0042887;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009979.1|UniProtKB=W5MUZ3 W5MUZ3 SPDEF PTHR11849:SF182 ETS SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000012772.1|UniProtKB=W5N515 W5N515 PTHR19134:SF328 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 9B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010498.1|UniProtKB=W5MWW1 W5MWW1 PTHR21236:SF6 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF5 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;Golgi organization#GO:0007030;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005772.1|UniProtKB=W5MF22 W5MF22 PTHR22594:SF34 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004224.1|UniProtKB=W5M9I9 W5M9I9 PTHR23098:SF22 AGAP001331-PA-RELATED MYB-LIKE DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000491.1|UniProtKB=W5LWN5 W5LWN5 PTHR36681:SF3 NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3 NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3 LEPOC|Ensembl=ENSLOCG00000000581.1|UniProtKB=W5LWY9 W5LWY9 PTHR19846:SF0 WD40 REPEAT PROTEIN PRE-MRNA PROCESSING FACTOR 4 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 mRNA splicing#P00058>U4#P01476;mRNA splicing#P00058>U6#P01473 LEPOC|Ensembl=ENSLOCG00000013366.1|UniProtKB=W5N783 W5N783 PTHR19325:SF43 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000016084.1|UniProtKB=W5NGQ8 W5NGQ8 PTHR11214:SF25 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000011825.1|UniProtKB=W5N1N7 W5N1N7 PTHR23113:SF150 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 PI3 kinase pathway#P00048>SOS#P01185;T cell activation#P00053>SOS#P01307;Angiogenesis#P00005>SOS-1#P00193;Integrin signalling pathway#P00034>SOS#P00920;PDGF signaling pathway#P00047>SOS#P01159;B cell activation#P00010>SOS#P00379;Ras Pathway#P04393>SOS#P04552;Interleukin signaling pathway#P00036>SOS#P00981;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;FGF signaling pathway#P00021>SOS#P00641;EGF receptor signaling pathway#P00018>SOS#P00558;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883 LEPOC|Ensembl=ENSLOCG00000014713.1|UniProtKB=W5NBV5 W5NBV5 PTHR22691:SF1 YEAST SPT2-RELATED CENTROSOMAL PROTEIN CCDC61 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002742.1|UniProtKB=W5M4C1 W5M4C1 PTHR23235:SF175 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016498.1|UniProtKB=W5NIC1 W5NIC1 PTHR46921:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 neuron apoptotic process#GO:0051402;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;humoral immune response#GO:0006959;negative regulation of cell-cell adhesion#GO:0022408;regulation of system process#GO:0044057;regulation of multicellular organismal development#GO:2000026;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of multicellular organismal process#GO:0051241;adaptive immune response#GO:0002250;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;regulation of T cell proliferation#GO:0042129;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of leukocyte proliferation#GO:0070663;regulation of B cell proliferation#GO:0030888 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004524.1|UniProtKB=W5MAK9 W5MAK9 PTHR24092:SF52 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE FETA ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000913.1|UniProtKB=W5LY26 W5LY26 PTHR11521:SF20 TROPONIN T TROPONIN T2E, CARDIAC ISOFORM X1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;circulatory system process#GO:0003013;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle contraction#GO:0006941;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000013473.1|UniProtKB=W5N7L1 W5N7L1 PTHR31915:SF10 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN 2 LEPOC|Ensembl=ENSLOCG00000012654.1|UniProtKB=W5N4L6 W5N4L6 MED20 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003078.1|UniProtKB=W5M5G3 W5M5G3 PTHR13869:SF38 MYELIN P0 RELATED NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016891.1|UniProtKB=W5NJS0 W5NJS0 PTHR24365:SF539 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016783.1|UniProtKB=W5NJE1 W5NJE1 PTHR13677:SF2 LD41638P PROTEIN DENND6B cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008128.1|UniProtKB=W5MNA8 W5MNA8 PTHR15723:SF0 CARBOHYDRATE SULFOTRANSFERASE 15 CARBOHYDRATE SULFOTRANSFERASE 15 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 hexose biosynthetic process#GO:0019319;monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010327.1|UniProtKB=W5MWA2 W5MWA2 PTHR23280:SF4 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4A cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000016211.1|UniProtKB=W5NH75 W5NH75 PTHR14215:SF2 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 2 cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organelle organization#GO:0006996;generation of precursor metabolites and energy#GO:0006091;organelle fission#GO:0048285;cellular metabolic process#GO:0044237;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial fission#GO:0000266;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016632.1|UniProtKB=W5NIT6 W5NIT6 PTHR10746:SF6 50S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011819.1|UniProtKB=W5N1M1 W5N1M1 PTHR45659:SF10 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017412.1|UniProtKB=W5NLK8 W5NLK8 PTHR10614:SF11 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 1 protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>IRS1#P07106;Gonadotropin-releasing hormone receptor pathway#P06664>IRS-1#P06825;Interleukin signaling pathway#P00036>IRS1/2#P00980;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;PI3 kinase pathway#P00048>IRS#P01193;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 LEPOC|Ensembl=ENSLOCG00000012350.1|UniProtKB=W5N3J8 W5N3J8 PTHR15528:SF10 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011645.1|UniProtKB=W5N0Z7 W5N0Z7 PTHR11202:SF4 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER ENA_VASP-LIKE PROTEIN protein binding#GO:0005515;SH3 domain binding#GO:0017124;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516 LEPOC|Ensembl=ENSLOCG00000014551.1|UniProtKB=W5NBA3 W5NBA3 PTHR45689:SF4 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;regulation of membrane depolarization#GO:0003254;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003219.1|UniProtKB=W5M5Z5 W5M5Z5 PTHR34755:SF1 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;mRNA processing#GO:0006397;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004730.1|UniProtKB=W5MBC1 W5MBC1 PTHR46130:SF2 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013129.1|UniProtKB=W5N6E5 W5N6E5 PTHR10574:SF36 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-2 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000016756.1|UniProtKB=W5NJA1 W5NJA1 PTHR23005:SF3 RETINITIS PIGMENTOSA 1 PROTEIN RETINITIS PIGMENTOSA 1-LIKE 1 PROTEIN cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;retina development in camera-type eye#GO:0060041;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;visual system development#GO:0150063;sensory system development#GO:0048880;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;eye development#GO:0001654;neuron development#GO:0048666;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000017425.1|UniProtKB=W5NLM1 W5NLM1 PTHR20994:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macroautophagy#GO:0016236;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;protein metabolic process#GO:0019538;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000012572.1|UniProtKB=W5N4B7 W5N4B7 PTHR11085:SF1 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000926.1|UniProtKB=W5LY27 W5LY27 PTHR10656:SF35 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE nucleic acid binding#GO:0003676;transferase activity#GO:0016740;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;DNA binding#GO:0003677;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 positive regulation of gene expression#GO:0010628;regulation of double-strand break repair#GO:2000779;positive regulation of type I interferon production#GO:0032481;activation of immune response#GO:0002253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;DNA damage response#GO:0006974;regulation of cellular response to stress#GO:0080135;positive regulation of cytokine production#GO:0001819;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of defense response#GO:0031349;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;negative regulation of DNA repair#GO:0045738;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to organic cyclic compound#GO:0071407;regulation of immune system process#GO:0002682;negative regulation of DNA recombination#GO:0045910;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;positive regulation of response to biotic stimulus#GO:0002833 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013642.1|UniProtKB=W5N868 W5N868 PTHR16200:SF4 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ARKADIA SMAD binding#GO:0046332;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein binding#GO:0032182;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;SUMO binding#GO:0032183 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of cellular response to growth factor stimulus#GO:0090287;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cell communication#GO:0010646;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002793.1|UniProtKB=W5M4H6 W5M4H6 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010632.1|UniProtKB=W5MXB3 W5MXB3 PTHR23327:SF5 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007367.1|UniProtKB=W5MKM2 W5MKM2 PTHR23339:SF119 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011147.1|UniProtKB=W5MZ84 W5MZ84 CLPS PTHR10041:SF9 COLIPASE COLIPASE protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011632.1|UniProtKB=W5N0Y7 W5N0Y7 PTHR45624:SF7 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 48 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004513.1|UniProtKB=W5MAI9 W5MAI9 PTHR15963:SF3 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED PROTEIN TAMALIN LEPOC|Ensembl=ENSLOCG00000002836.1|UniProtKB=W5M4M7 W5M4M7 PTHR24390:SF228 ZINC FINGER PROTEIN PROTEIN KRUEPPEL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005186.1|UniProtKB=W5MCY7 W5MCY7 PTHR15923:SF1 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN LIPOLYSIS-STIMULATED LIPOPROTEIN RECEPTOR cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012591.1|UniProtKB=W5N4E5 W5N4E5 PTHR21562:SF7 NOTUM-RELATED PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;lipoprotein metabolic process#GO:0042157 LEPOC|Ensembl=ENSLOCG00000003175.1|UniProtKB=W5M5U2 W5M5U2 CCDC60 PTHR34754:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 LEPOC|Ensembl=ENSLOCG00000013902.1|UniProtKB=W5N934 W5N934 PTHR45928:SF2 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 35 LEPOC|Ensembl=ENSLOCG00000001744.1|UniProtKB=W5M0V4 W5M0V4 PTHR21107:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001655.1|UniProtKB=W5M0K2 W5M0K2 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001268.1|UniProtKB=W5LZ82 W5LZ82 PTHR19354:SF6 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 3-RELATED regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of synapse structure or activity#GO:0050803;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of postsynapse organization#GO:0099175;regulation of neuron projection development#GO:0010975 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;dendritic spine#GO:0043197 LEPOC|Ensembl=ENSLOCG00000010350.1|UniProtKB=W5MWC6 W5MWC6 PTHR36473:SF1 CHROMOSOME 3 OPEN READING FRAME 49 GENE 11100-RELATED LEPOC|Ensembl=ENSLOCG00000013987.1|UniProtKB=W5N9D4 W5N9D4 PTHR20855:SF38 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002685.1|UniProtKB=W5M444 W5M444 PTHR15929:SF0 STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR LEPOC|Ensembl=ENSLOCG00000004831.1|UniProtKB=W5MBP2 W5MBP2 PTHR12081:SF40 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004765.1|UniProtKB=W5MBG1 W5MBG1 PTHR12027:SF7 WNT RELATED PROTEIN WNT-11 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000006317.1|UniProtKB=W5MGY9 W5MGY9 PTHR13008:SF7 MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>MADD#P00267 LEPOC|Ensembl=ENSLOCG00000013082.1|UniProtKB=W5N655 W5N655 PTHR45869:SF7 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN LEPOC|Ensembl=ENSLOCG00000010492.1|UniProtKB=W5MWV5 W5MWV5 TADA1 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124 LEPOC|Ensembl=ENSLOCG00000002671.1|UniProtKB=W5M445 W5M445 PTHR11730:SF120 AMMONIUM TRANSPORTER RH BLOOD GROUP, D ANTIGEN inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007471.1|UniProtKB=W5ML12 W5ML12 PTHR11647:SF55 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 4 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 LEPOC|Ensembl=ENSLOCG00000015958.1|UniProtKB=W5NG98 W5NG98 JAG1 PTHR24044:SF448 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 LEPOC|Ensembl=ENSLOCG00000006116.1|UniProtKB=W5MG83 W5MG83 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 16 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014279.1|UniProtKB=W5NAB9 W5NAB9 PTHR12577:SF7 DACHSHUND DACHSHUND HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005237.1|UniProtKB=W5MD50 W5MD50 PTHR24028:SF41 CADHERIN-87A PROTOCADHERIN-17 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000013585.1|UniProtKB=W5N7Z6 W5N7Z6 PTHR13610:SF8 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;peptidyl-amino acid modification#GO:0018193;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;positive regulation of transporter activity#GO:0032411;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008079.1|UniProtKB=W5MN65 W5MN65 PTHR11134:SF31 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-1 COMPLEX SUBUNIT BETA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010591.1|UniProtKB=W5MX62 W5MX62 PTHR11711:SF163 ADP RIBOSYLATION FACTOR-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM23 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011177.1|UniProtKB=W5MZC3 W5MZC3 C18orf25 PTHR16200:SF5 RING ZINC FINGER PROTEIN ARK2N transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007173.1|UniProtKB=W5MJX1 W5MJX1 PTHR11848:SF144 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000005743.1|UniProtKB=W5MEX8 W5MEX8 PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002888.1|UniProtKB=W5M4T8 W5M4T8 PTHR31526:SF2 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006229.1|UniProtKB=W5MGL9 W5MGL9 PTHR10288:SF101 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013019.1|UniProtKB=W5N5X8 W5N5X8 PTHR19282:SF550 TETRASPANIN TETRASPANIN-10 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005481.1|UniProtKB=W5ME01 W5ME01 PTHR24012:SF728 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA splice site recognition#GO:0006376;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002956.1|UniProtKB=W5M528 W5M528 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009176.1|UniProtKB=W5MS32 W5MS32 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000018072.1|UniProtKB=W5NNG4 W5NNG4 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001617.1|UniProtKB=W5M0F4 W5M0F4 KIAA0825 PTHR33960:SF1 SIMILAR TO KIAA0825 PROTEIN SIMILAR TO KIAA0825 PROTEIN LEPOC|Ensembl=ENSLOCG00000006979.1|UniProtKB=W5MJ86 W5MJ86 PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN LEPOC|Ensembl=ENSLOCG00000011040.1|UniProtKB=W5MYT9 W5MYT9 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017782.1|UniProtKB=W5NMM7 W5NMM7 PTHR45773:SF5 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 5 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012846.1|UniProtKB=W5N5A0 W5N5A0 PTHR28573:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;cell division#GO:0051301;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cellular component organization#GO:0051128;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;outer kinetochore#GO:0000940;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000002896.1|UniProtKB=W5M4W5 W5M4W5 NAT10 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009516.1|UniProtKB=W5MTC1 W5MTC1 PTHR23235:SF42 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CCKR signaling map#P06959>EGR1#P07192;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06887;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06672;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#P06837;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>EGR#P05931 LEPOC|Ensembl=ENSLOCG00000013383.1|UniProtKB=W5N788 W5N788 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010287.1|UniProtKB=W5MW41 W5MW41 PTHR10913:SF9 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 4 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000004969.1|UniProtKB=W5MC69 W5MC69 PTHR15031:SF0 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000007457.1|UniProtKB=W5MKY8 W5MKY8 PTHR20437:SF3 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 BCMA TALL-1 BINDING DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016643.1|UniProtKB=W5NIV2 W5NIV2 PTHR20855:SF33 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 LEPOC|Ensembl=ENSLOCG00000012497.1|UniProtKB=W5N433 W5N433 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000007214.1|UniProtKB=W5MK37 W5MK37 PTHR23192:SF27 OLFACTOMEDIN-RELATED NOELIN-2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016005.1|UniProtKB=W5NGF3 W5NGF3 PTHR12025:SF5 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR A, LONG FORM molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;response to abiotic stimulus#GO:0009628;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to hypoxia#GO:0001666;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;positive regulation of leukocyte migration#GO:0002687;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of immune system process#GO:0002682;signaling#GO:0023052;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of response to external stimulus#GO:0032101;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of leukocyte chemotaxis#GO:0002690 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 VEGF signaling pathway#P00056>VEGF#P01406;Angiogenesis#P00005>VEGF#P00241 LEPOC|Ensembl=ENSLOCG00000015733.1|UniProtKB=W5NFG2 W5NFG2 XPO5 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017534.1|UniProtKB=W5NLY0 W5NLY0 PTHR24247:SF20 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1A cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 LEPOC|Ensembl=ENSLOCG00000000382.1|UniProtKB=W5LWA9 W5LWA9 PTHR11440:SF18 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000012203.1|UniProtKB=W5N305 W5N305 PTHR24240:SF55 OPSIN OPSIN 5-LIKE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013256.1|UniProtKB=W5N6S2 W5N6S2 PTHR12886:SF0 PIG-M MANNOSYLTRANSFERASE GPI MANNOSYLTRANSFERASE 1 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;mannosyltransferase complex#GO:0031501;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006144.1|UniProtKB=W5MGB3 W5MGB3 PTHR21456:SF2 FAMILY WITH SEQUENCE SIMILARITY 102 EARLY ESTROGEN-INDUCED GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000017013.1|UniProtKB=W5NK69 W5NK69 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000017310.1|UniProtKB=W5NLA6 W5NLA6 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015083.1|UniProtKB=W5ND59 W5ND59 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;transferase activity#GO:0016740;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;IMP metabolic process#GO:0046040;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247 LEPOC|Ensembl=ENSLOCG00000014405.1|UniProtKB=W5NAS4 W5NAS4 PTHR45911:SF2 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000009340.1|UniProtKB=W5MSN5 W5MSN5 PTHR13609:SF20 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011517.1|UniProtKB=W5N0J0 W5N0J0 PTHR12599:SF13 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000016613.1|UniProtKB=W5NIR2 W5NIR2 PTHR24412:SF10 KELCH PROTEIN KELCH-LIKE PROTEIN 29 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015886.1|UniProtKB=W5NG06 W5NG06 TP53I3 PTHR48106:SF18 QUINONE OXIDOREDUCTASE PIG3-RELATED QUINONE OXIDOREDUCTASE PIG3 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on NAD(P)H#GO:0016651;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000010809.1|UniProtKB=W5MXZ4 W5MXZ4 PTHR23282:SF140 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017735.1|UniProtKB=W5NMI0 W5NMI0 PTHR21255:SF61 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN CONTAINING 1 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000808.1|UniProtKB=W5LXP3 W5LXP3 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 TRANSMEMBRANE PROTEIN 199 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000015919.1|UniProtKB=W5NG43 W5NG43 PTHR21032:SF0 G PATCH DOMAIN-CONTAINING PROTEIN 11 G PATCH DOMAIN-CONTAINING PROTEIN 11 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005539.1|UniProtKB=W5ME92 W5ME92 SHCBP1 PTHR14695:SF8 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED SHC SH2 DOMAIN-BINDING PROTEIN 1 fibroblast growth factor receptor signaling pathway#GO:0008543;male gamete generation#GO:0048232;cell division#GO:0051301;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;response to growth factor#GO:0070848;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;response to fibroblast growth factor#GO:0071774;response to endogenous stimulus#GO:0009719;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;cytoskeleton-dependent cytokinesis#GO:0061640;reproductive process#GO:0022414;male meiotic nuclear division#GO:0007140;signaling#GO:0023052;cytokinesis#GO:0000910;multicellular organismal reproductive process#GO:0048609;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;cellular response to endogenous stimulus#GO:0071495;meiotic cell cycle#GO:0051321;multicellular organism reproduction#GO:0032504;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;sexual reproduction#GO:0019953;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;cellular response to fibroblast growth factor stimulus#GO:0044344 LEPOC|Ensembl=ENSLOCG00000007417.1|UniProtKB=W5MKW0 W5MKW0 PTHR14043:SF5 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014128.1|UniProtKB=W5N9U7 W5N9U7 PTHR42782:SF2 SI:CH73-314G15.3 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000008440.1|UniProtKB=W5MPF6 W5MPF6 PTHR11733:SF128 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED KELL BLOOD GROUP GLYCOPROTEIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003740.1|UniProtKB=W5M7V2 W5M7V2 PTHR10621:SF28 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 proteasome binding#GO:0070628;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001057.1|UniProtKB=W5LYI3 W5LYI3 PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000406.1|UniProtKB=W5LWD5 W5LWD5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017064.1|UniProtKB=W5NKD0 W5NKD0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000005664.1|UniProtKB=W5MEN9 W5MEN9 PTHR16001:SF6 ECTO-NOX DISULFIDE-THIOL EXCHANGER ECTO-NOX DISULFIDE-THIOL EXCHANGER 1 isomerase activity#GO:0016853;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017111.1|UniProtKB=W5NKI8 W5NKI8 PTHR11255:SF92 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE IOTA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007161.1|UniProtKB=W5MJV3 W5MJV3 HOXD13 PTHR45804:SF3 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-A13 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011764.1|UniProtKB=W5N1G2 W5N1G2 PTHR24031:SF125 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX42 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000017402.1|UniProtKB=W5NLJ8 W5NLJ8 PTHR10270:SF107 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;head development#GO:0060322;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000005330.1|UniProtKB=W5MDG7 W5MDG7 PTHR45862:SF1 PROTEIN SGT1 HOMOLOG PROTEIN SGT1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000013083.1|UniProtKB=W5N656 W5N656 PTHR13386:SF1 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stress#GO:0033554;regulation of catalytic activity#GO:0050790;regulation of transferase activity#GO:0051338 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000008598.1|UniProtKB=W5MPZ7 W5MPZ7 PTHR24055:SF79 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 15 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ERK#P00907;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Ras Pathway#P04393>ERK#P04542;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>ERK1-2#P00627;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Toll receptor signaling pathway#P00054>ERK1#P01358;Apoptosis signaling pathway#P00006>MAPK#P00269;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 LEPOC|Ensembl=ENSLOCG00000003908.1|UniProtKB=W5M8F4 W5M8F4 TCFL5 PTHR15402:SF2 TRANSCRIPTION FACTOR-LIKE 5 PROTEIN TRANSCRIPTION FACTOR LIKE 5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017244.1|UniProtKB=W5NL19 W5NL19 PTHR12874:SF9 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 48 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001676.1|UniProtKB=W5M0R7 W5M0R7 PTHR45656:SF6 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016289.1|UniProtKB=W5NHJ2 W5NHJ2 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S16 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015847.1|UniProtKB=W5NFV7 W5NFV7 PTHR24060:SF26 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000002693.1|UniProtKB=W5M453 W5M453 PTHR11537:SF65 VOLTAGE-GATED POTASSIUM CHANNEL BTB DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014179.1|UniProtKB=W5NA05 W5NA05 PTHR16655:SF2 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000005623.1|UniProtKB=W5MEH9 W5MEH9 PTHR15601:SF20 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 2 response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014387.1|UniProtKB=W5NAQ3 W5NAQ3 PTHR45623:SF19 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 2 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013207.1|UniProtKB=W5N6K9 W5N6K9 PTHR15441:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P PROTEIN SUBUNIT P14 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoribonuclease complex#GO:1902555;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014638.1|UniProtKB=W5NBK9 W5NBK9 PTHR10454:SF155 CASPASE CASPASE-14-LIKE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001771.1|UniProtKB=W5M0Y7 W5M0Y7 PTHR12483:SF8 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS PROTEIN SLC31A2 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018195.1|UniProtKB=W5NNT7 W5NNT7 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015360.1|UniProtKB=W5NE44 W5NE44 PTHR13544:SF6 SELENOPROTEIN T SELENOPROTEIN T2 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016257.1|UniProtKB=W5NHE0 W5NHE0 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018029.1|UniProtKB=W5NNC1 W5NNC1 PTHR26451:SF989 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005668.1|UniProtKB=W5MEN4 W5MEN4 PTHR11955:SF67 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER-RELATED fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000004316.1|UniProtKB=W5M9V6 W5M9V6 PTHR23030:SF30 PCD6 INTERACTING PROTEIN-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002725.1|UniProtKB=W5M497 W5M497 PTHR31954:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009733.1|UniProtKB=W5MU28 W5MU28 PTHR45834:SF8 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007111.1|UniProtKB=W5MJQ5 W5MJQ5 PTHR21229:SF11 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR108 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002000.1|UniProtKB=W5M1R4 W5M1R4 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692 LEPOC|Ensembl=ENSLOCG00000010733.1|UniProtKB=W5MXN6 W5MXN6 PTHR24246:SF1 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000007035.1|UniProtKB=W5MJG8 W5MJG8 PTHR24057:SF8 GLYCOGEN SYNTHASE KINASE-3 ALPHA GLYCOGEN SYNTHASE KINASE-3 BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;beta-catenin binding#GO:0008013;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular component organization#GO:0051128;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of protein catabolic process#GO:0042176;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;regulation of microtubule cytoskeleton organization#GO:0070507;cellular response to insulin stimulus#GO:0032869;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of TOR signaling#GO:0032006;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to hormone#GO:0009725;peptidyl-threonine phosphorylation#GO:0018107;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Glycogen Synthase Kinase-3Beta#P01441;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PI3 kinase pathway#P00048>GSK3#P01181;Interleukin signaling pathway#P00036>GSK3#P00976;Ras Pathway#P04393>GSK3#P04546;Angiogenesis#P00005>GSK3beta#P00211;Cadherin signaling pathway#P00012>GSK3beta#P00477;Hedgehog signaling pathway#P00025>GSK3#P00692;CCKR signaling map#P06959>GSK3beta#P07199;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GSK#P00714;Gonadotropin-releasing hormone receptor pathway#P06664>GSK3#P06827;PDGF signaling pathway#P00047>GSK3#P01153 LEPOC|Ensembl=ENSLOCG00000002314.1|UniProtKB=W5M2V0 W5M2V0 PTHR20920:SF6 RPE-SPONDIN SOMATOMEDIN B AND THROMBOSPONDIN TYPE 1 DOMAIN CONTAINING LEPOC|Ensembl=ENSLOCG00000016174.1|UniProtKB=W5NH21 W5NH21 PTHR24058:SF51 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016727.1|UniProtKB=W5NJ60 W5NJ60 PTHR16768:SF1 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B LEPOC|Ensembl=ENSLOCG00000006129.1|UniProtKB=W5MG94 W5MG94 PTHR14647:SF62 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011048.1|UniProtKB=W5MYV3 W5MYV3 PTHR11250:SF4 TACHYKININ PREPROTACHYKININ 1 LEPOC|Ensembl=ENSLOCG00000008839.1|UniProtKB=W5MQU8 W5MQU8 TNFAIP8 PTHR12757:SF3 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Huntington disease#P00029>FIP-2#P00772 LEPOC|Ensembl=ENSLOCG00000017432.1|UniProtKB=W5NLM8 W5NLM8 PTHR12002:SF89 CLAUDIN CLAUDIN-4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000005410.1|UniProtKB=W5MDR4 W5MDR4 PTHR11559:SF391 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004872.1|UniProtKB=W5MBV4 W5MBV4 PTHR14002:SF45 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZP DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001209.1|UniProtKB=W5LZ10 W5LZ10 PTHR23113:SF167 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008288.1|UniProtKB=W5MNV6 W5MNV6 PTHR12369:SF40 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 3 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006439.1|UniProtKB=W5MHC8 W5MHC8 PTHR11566:SF225 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX-RELATED pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 response to external biotic stimulus#GO:0043207;response to virus#GO:0009615;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;receptor internalization#GO:0031623;membrane organization#GO:0061024;transport#GO:0006810;synaptic vesicle recycling#GO:0036465;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;defense response to virus#GO:0051607;defense response#GO:0006952;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;defense response to symbiont#GO:0140546;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;vesicle budding from membrane#GO:0006900;defense response to other organism#GO:0098542;organelle organization#GO:0006996;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 supramolecular complex#GO:0099080;synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014097.1|UniProtKB=W5N9R0 W5N9R0 BICD2 PTHR31233:SF7 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006412.1|UniProtKB=W5MHB2 W5MHB2 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;organonitrogen compound catabolic process#GO:1901565;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;ceramide biosynthetic process#GO:0046513;phospholipid catabolic process#GO:0009395;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010373.1|UniProtKB=W5MWH5 W5MWH5 PTHR24222:SF76 ABC TRANSPORTER B FAMILY MYCOBACTIN IMPORT ATP-BINDING_PERMEASE PROTEIN IRTB transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006421.1|UniProtKB=W5MH98 W5MH98 PTHR11955:SF152 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 2 fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009612.1|UniProtKB=W5MTN6 W5MTN6 TMPRSS15 PTHR24253:SF71 TRANSMEMBRANE PROTEASE SERINE ENTEROPEPTIDASE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009298.1|UniProtKB=W5MSJ2 W5MSJ2 PTHR11690:SF252 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 1C monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014896.1|UniProtKB=W5NCI3 W5NCI3 PTHR14186:SF25 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PEPTIDASE INHIBITOR DOMAIN 3 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013626.1|UniProtKB=W5N840 W5N840 PTHR18063:SF8 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-2 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein K48-linked deubiquitination#GO:0071108;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017110.1|UniProtKB=W5NKI5 W5NKI5 PTHR10896:SF8 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 2 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008970.1|UniProtKB=W5MRF1 W5MRF1 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003456.1|UniProtKB=W5M6T6 W5M6T6 PTHR48024:SF28 GEO13361P1-RELATED RNA-BINDING PROTEIN 38 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015500.1|UniProtKB=W5NEL8 W5NEL8 PTHR11726:SF10 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011117.1|UniProtKB=W5MZ68 W5MZ68 PTHR13817:SF16 TITIN MYOMESIN-1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013931.1|UniProtKB=W5N972 W5N972 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cardiolipin biosynthetic process#GO:0032049;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016022.1|UniProtKB=W5NGH5 W5NGH5 PTHR44858:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 6 UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED LEPOC|Ensembl=ENSLOCG00000017506.1|UniProtKB=W5NLV2 W5NLV2 PTHR19290:SF32 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000015509.1|UniProtKB=W5NEN0 W5NEN0 PTHR17597:SF0 MEMBRANE PROTEIN MLC1 MEMBRANE PROTEIN MLC1 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001372.1|UniProtKB=W5LZL0 W5LZL0 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG LEPOC|Ensembl=ENSLOCG00000007429.1|UniProtKB=W5MKV8 W5MKV8 BOP1 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008271.1|UniProtKB=W5MNW1 W5MNW1 PTHR10199:SF89 THROMBOSPONDIN THROMBOSPONDIN-3 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006919.1|UniProtKB=W5MJ15 W5MJ15 PTHR10048:SF35 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900 LEPOC|Ensembl=ENSLOCG00000014813.1|UniProtKB=W5NC83 W5NC83 PTHR12879:SF22 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 DELTA 4-DESATURASE, SPHINGOLIPID 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000016135.1|UniProtKB=W5NGX2 W5NGX2 PTHR45993:SF5 B-CELL LYMPHOMA/LEUKEMIA 11 B-CELL LYMPHOMA_LEUKEMIA 11A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of dendrite development#GO:0050773;negative regulation of biological process#GO:0048519;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009930.1|UniProtKB=W5MUU4 W5MUU4 SLC2A9 PTHR23503:SF35 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 9 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001461.1|UniProtKB=W5LZW3 W5LZW3 PTHR46485:SF2 LIM DOMAIN KINASE 1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004088.1|UniProtKB=W5M927 W5M927 PTHR23281:SF20 MERLIN/MOESIN/EZRIN/RADIXIN NF2, MOESIN-EZRIN-RADIXIN-LIKE (MERLIN) TUMOR SUPPRESSOR B cytoskeletal protein binding#GO:0008092;integrin binding#GO:0005178;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;actin binding#GO:0003779 negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of intracellular signal transduction#GO:1902531;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;regulation of organelle assembly#GO:1902115;negative regulation of cell population proliferation#GO:0008285;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;regulation of cell development#GO:0060284;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829 filopodium#GO:0030175;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;actin-based cell projection#GO:0098858;adherens junction#GO:0005912;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017179.1|UniProtKB=W5NKS3 W5NKS3 PTHR16458:SF2 GLYCINE N-METHYLTRANSFERASE GLYCINE N-METHYLTRANSFERASE amino acid binding#GO:0016597;N-methyltransferase activity#GO:0008170;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;cation binding#GO:0043169;transferase activity#GO:0016740;carboxylic acid binding#GO:0031406;identical protein binding#GO:0042802;protein binding#GO:0005515;transferase activity, transferring one-carbon groups#GO:0016741;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;protein-containing complex assembly#GO:0065003;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;glycosyl compound metabolic process#GO:1901657;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;regulation of metabolic process#GO:0019222;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016300.1|UniProtKB=W5NHK7 W5NHK7 PTPRQ PTHR46957:SF1 CYTOKINE RECEPTOR PHOSPHATIDYLINOSITOL PHOSPHATASE PTPRQ negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003489.1|UniProtKB=W5M6Y0 W5M6Y0 PTHR13866:SF21 SPARC OSTEONECTIN TESTICAN-3 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000006926.1|UniProtKB=W5MJ14 W5MJ14 PTHR23167:SF87 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003422.1|UniProtKB=W5M6N9 W5M6N9 PTHR22957:SF207 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10B nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000000418.1|UniProtKB=W5LWF1 W5LWF1 PTHR12998:SF0 TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000012445.1|UniProtKB=W5N3W1 W5N3W1 PTHR24335:SF3 MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;central nervous system neuron differentiation#GO:0021953;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;cell fate commitment#GO:0045165;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cell fate specification#GO:0001708;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;central nervous system development#GO:0007417;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004393.1|UniProtKB=W5MA43 W5MA43 PTHR13598:SF4 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 1 envelope#GO:0031975;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012317.1|UniProtKB=W5N3G5 W5N3G5 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015802.1|UniProtKB=W5NFQ4 W5NFQ4 PTHR13743:SF86 BEIGE/BEACH-RELATED LYSOSOMAL-TRAFFICKING REGULATOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009059.1|UniProtKB=W5MRN0 W5MRN0 PTHR12369:SF14 CHONDROITIN SYNTHASE CHONDROITIN SULFATE GLUCURONYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000005266.1|UniProtKB=W5MD86 W5MD86 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004307.1|UniProtKB=W5M9U1 W5M9U1 OCLN PTHR23288:SF4 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell junction assembly#GO:0034329;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;cell-cell junction organization#GO:0045216;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;cell-cell junction assembly#GO:0007043;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;tight junction#GO:0070160;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;apical junction complex#GO:0043296;plasma membrane#GO:0005886 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007660.1|UniProtKB=W5MLN9 W5MLN9 PTHR46257:SF4 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 B cell activation#P00010>SHP-1#P00378;FGF signaling pathway#P00021>SHP2#P00647;Angiogenesis#P00005>SHP2#P00181;Interferon-gamma signaling pathway#P00035>PTP#P00960 LEPOC|Ensembl=ENSLOCG00000009069.1|UniProtKB=W5MRQ1 W5MRQ1 PTHR13844:SF5 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000007487.1|UniProtKB=W5ML30 W5ML30 PANX PTHR15759:SF5 PANNEXIN PANNEXIN-1 wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001156.1|UniProtKB=W5LYY3 W5LYY3 PTHR10201:SF151 MATRIX METALLOPROTEINASE INTERSTITIAL COLLAGENASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Plasminogen activating cascade#P00050>pro-MMP-1#P01263;Plasminogen activating cascade#P00050>MMP-1#P01252;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000001709.1|UniProtKB=W5M0R4 W5M0R4 PTHR47977:SF26 RAS-RELATED PROTEIN RAB RAB1B, MEMBER RAS ONCO FAMILY GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000003618.1|UniProtKB=W5M7D3 W5M7D3 PTHR13817:SF164 TITIN ZORMIN, ISOFORM J structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000018090.1|UniProtKB=W5NNI2 W5NNI2 PTHR11767:SF14 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 12-RELATED monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003929.1|UniProtKB=W5M8J0 W5M8J0 PTHR11923:SF94 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2 cargo receptor activity#GO:0038024 cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of catalytic activity#GO:0050790;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;endocytosis#GO:0006897;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015251.1|UniProtKB=W5NDQ8 W5NDQ8 PTHR11506:SF6 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 2 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003531.1|UniProtKB=W5M716 W5M716 PTHR45617:SF2 LEUCINE RICH REPEAT FAMILY PROTEIN INSULIN LIKE GROWTH FACTOR BINDING PROTEIN ACID LABILE SUBUNIT scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015887.1|UniProtKB=W5NG09 W5NG09 PTHR48019:SF168 SERUM RESPONSE FACTOR HOMOLOG SERUM RESPONSE FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 MADS box transcription factor#PC00250 CCKR signaling map#P06959>SRF#P07181;p38 MAPK pathway#P05918>SRF#P06025;PDGF signaling pathway#P00047>c-fos#P01145;Ras Pathway#P04393>SRF#P04561;Gonadotropin-releasing hormone receptor pathway#P06664>SRF#P06811;Interleukin signaling pathway#P00036>SRF#P00987;PDGF signaling pathway#P00047>SRF#P01165 LEPOC|Ensembl=ENSLOCG00000011946.1|UniProtKB=W5N234 W5N234 PTHR11177:SF248 CHITINASE CHITOTRIOSIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015768.1|UniProtKB=W5NFK3 W5NFK3 PTHR28366:SF1 CHROMOSOME 1 OPEN READING FRAME 131 CHROMOSOME 1 OPEN READING FRAME 131 LEPOC|Ensembl=ENSLOCG00000006600.1|UniProtKB=W5MHW0 W5MHW0 PTHR45646:SF6 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK2 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;peptidyl-tyrosine modification#GO:0018212;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015917.1|UniProtKB=W5NG40 W5NG40 PTHR24366:SF15 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN 2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007753.1|UniProtKB=W5MM08 W5MM08 PTHR46202:SF1 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014273.1|UniProtKB=W5NAB2 W5NAB2 PTHR23341:SF4 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMGI-C molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000002118.1|UniProtKB=W5M273 W5M273 PTHR47958:SF31 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010435.1|UniProtKB=W5MWN9 W5MWN9 PTHR11785:SF213 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 2 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004431.1|UniProtKB=W5MA90 W5MA90 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006506.1|UniProtKB=W5MHK8 W5MHK8 PTHR24270:SF3 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 8 multicellular organismal process#GO:0032501;system development#GO:0048731;central nervous system development#GO:0007417;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 plasma membrane raft#GO:0044853;caveola#GO:0005901;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000016255.1|UniProtKB=W5NHD5 W5NHD5 PTHR11537:SF172 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;presynaptic membrane#GO:0042734;cell leading edge#GO:0031252;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;distal axon#GO:0150034;postsynapse#GO:0098794;cell projection#GO:0042995;membrane protein complex#GO:0098796;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell projection membrane#GO:0031253;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013374.1|UniProtKB=W5N7A7 W5N7A7 PTHR13140:SF273 MYOSIN UNCONVENTIONAL MYOSIN-VA microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000008578.1|UniProtKB=W5MPX6 W5MPX6 PTHR11830:SF16 40S RIBOSOMAL PROTEIN S3A UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein K63-linked deubiquitination#GO:0070536;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000008602.1|UniProtKB=W5MPZ6 W5MPZ6 PTHR11866:SF33 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER THROMBOXANE A2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012351.1|UniProtKB=W5N3J3 W5N3J3 PTHR13628:SF1 TRANSMEMBRANE PROTEIN 267 TRANSMEMBRANE PROTEIN 267 LEPOC|Ensembl=ENSLOCG00000013846.1|UniProtKB=W5N8W8 W5N8W8 PTHR23355:SF30 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000006670.1|UniProtKB=W5MI45 W5MI45 PTHR22923:SF67 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006610.1|UniProtKB=W5MHX9 W5MHX9 PTHR19143:SF222 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3 lipid metabolic process#GO:0006629;negative regulation of hydrolase activity#GO:0051346;triglyceride homeostasis#GO:0070328;regulation of lipase activity#GO:0060191;regulation of phospholipase activity#GO:0010517;lipid catabolic process#GO:0016042;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of molecular function#GO:0065009;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phospholipid catabolic process#GO:0009395;lipid homeostasis#GO:0055088;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015785.1|UniProtKB=W5NFM4 W5NFM4 HNRNPLL PTHR15592:SF13 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009997.1|UniProtKB=W5MV14 W5MV14 PTHR12040:SF22 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1B protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008331.1|UniProtKB=W5MP09 W5MP09 PTHR46609:SF8 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010562.1|UniProtKB=W5MX33 W5MX33 PTHR34257:SF3 ADAPTER PROTEIN CIKS ADAPTER PROTEIN CIKS-RELATED positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;immune response#GO:0006955;humoral immune response#GO:0006959;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002859.1|UniProtKB=W5M4Q2 W5M4Q2 PTHR14356:SF2 INTERLEUKIN-15-RELATED INTERLEUKIN-21 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000001619.1|UniProtKB=W5M0G6 W5M0G6 PTHR10728:SF13 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 Oxidative stress response#P00046>cPLA2#P01134;Endothelin signaling pathway#P00019>cPLA2#P00583;Angiogenesis#P00005>PLA2#P00227;CCKR signaling map#P06959>PLA2#P07086;VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>cPLA2#P00251;Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855 LEPOC|Ensembl=ENSLOCG00000006856.1|UniProtKB=W5MIS6 W5MIS6 PTHR14487:SF3 ADRENOCORTICAL DYSPLASIA PROTEIN ACD ADRENOCORTICAL DYSPLASIA PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000012116.1|UniProtKB=W5N2P9 W5N2P9 PTHR12306:SF8 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEA biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 LEPOC|Ensembl=ENSLOCG00000014978.1|UniProtKB=W5NCT0 W5NCT0 PTHR46099:SF4 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN RECEPTOR TYPE B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;system process#GO:0003008;pigmentation#GO:0043473;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;developmental pigmentation#GO:0048066;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>ET-RA/B#P00580 LEPOC|Ensembl=ENSLOCG00000014338.1|UniProtKB=W5NAK3 W5NAK3 PTHR11533:SF156 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009165.1|UniProtKB=W5MS27 W5MS27 PTHR14445:SF38 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;dendrite#GO:0030425;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell body#GO:0044297;perikaryon#GO:0043204;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000009084.1|UniProtKB=W5MRT4 W5MRT4 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000000119.1|UniProtKB=W5LVI1 W5LVI1 PTHR11771:SF161 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15B oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012206.1|UniProtKB=W5N315 W5N315 PTHR43330:SF7 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloaminopeptidase activity#GO:0070006 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016994.1|UniProtKB=W5NK54 W5NK54 SLC6A13 PTHR11616:SF111 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004731.1|UniProtKB=W5MBA8 W5MBA8 PTHR13504:SF34 FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145 PROTEIN ADENYLYLTRANSFERASE FICD LEPOC|Ensembl=ENSLOCG00000015526.1|UniProtKB=W5NEP8 W5NEP8 PTHR48071:SF4 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN-RELATED LEPOC|Ensembl=ENSLOCG00000004359.1|UniProtKB=W5MA08 W5MA08 PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012432.1|UniProtKB=W5N3U4 W5N3U4 PTHR11588:SF7 TUBULIN TUBULIN GAMMA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;organelle organization#GO:0006996;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;cell cycle#GO:0007049;organelle fission#GO:0048285;microtubule nucleation#GO:0007020 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000010717.1|UniProtKB=W5MXL9 W5MXL9 PTHR12876:SF36 N4BP1-RELATED RIBONUCLEASE ZC3H12C-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016097.1|UniProtKB=W5NGS4 W5NGS4 PTHR15664:SF6 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000011808.1|UniProtKB=W5N1L4 W5N1L4 PTHR34529:SF1 AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN LEPOC|Ensembl=ENSLOCG00000011767.1|UniProtKB=W5N1G0 W5N1G0 PTHR11346:SF104 GALECTIN GALECTIN-2 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002252.1|UniProtKB=W5M2M6 W5M2M6 PTHR13872:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007268.1|UniProtKB=W5MK96 W5MK96 PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000003101.1|UniProtKB=W5M5K7 W5M5K7 PTHR11105:SF0 CITRATE LYASE SUBUNIT BETA-RELATED CITRAMALYL-COA LYASE, MITOCHONDRIAL lyase#PC00144 Pyruvate metabolism#P02772>Citrate Lyase#P03137 LEPOC|Ensembl=ENSLOCG00000016690.1|UniProtKB=W5NJ11 W5NJ11 MANSC4 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000004261.1|UniProtKB=W5M9N7 W5M9N7 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003117.1|UniProtKB=W5M5N5 W5M5N5 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000009324.1|UniProtKB=W5MSP2 W5MSP2 PTHR23317:SF74 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 8 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of locomotion#GO:0040012;regulation of cell-cell adhesion#GO:0022407;regulation of lymphocyte migration#GO:2000401;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte migration#GO:0002687;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of molecular function#GO:0065009;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;regulation of multicellular organismal process#GO:0051239;regulation of cell motility#GO:2000145;regulation of GTPase activity#GO:0043087;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;positive regulation of locomotion#GO:0040017;positive regulation of immune system process#GO:0002684;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of leukocyte activation#GO:0002694;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of multicellular organismal process#GO:0051240 cell leading edge#GO:0031252;cellular anatomical entity#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000010186.1|UniProtKB=W5MVR2 W5MVR2 PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000018184.1|UniProtKB=W5NNS6 W5NNS6 PTHR24226:SF0 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G-PROTEIN COUPLED RECEPTOR 182 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017523.1|UniProtKB=W5NLW9 W5NLW9 PTHR24156:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34B LEPOC|Ensembl=ENSLOCG00000014236.1|UniProtKB=W5NA76 W5NA76 HNRNPUL1 PTHR12381:SF41 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015951.1|UniProtKB=W5NG80 W5NG80 PTHR11060:SF0 PROTEIN MEMO1 PROTEIN MEMO1 LEPOC|Ensembl=ENSLOCG00000017985.1|UniProtKB=W5NN77 W5NN77 PTHR10502:SF210 ANNEXIN PRION PROTEIN 1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000011373.1|UniProtKB=W5N030 W5N030 PTHR22948:SF14 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 7 negative regulation of gene expression#GO:0010629;male gamete generation#GO:0048232;sensory organ morphogenesis#GO:0090596;cellular component biogenesis#GO:0044085;regulatory ncRNA processing#GO:0070918;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;eye morphogenesis#GO:0048592;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;anatomical structure morphogenesis#GO:0009653;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;reproductive process#GO:0022414;sensory system development#GO:0048880;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;piRNA processing#GO:0034587;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;anterior/posterior pattern specification#GO:0009952;lens development in camera-type eye#GO:0002088;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;animal organ development#GO:0048513;developmental process#GO:0032502;RNA processing#GO:0006396;biosynthetic process#GO:0009058;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;visual system development#GO:0150063;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;regionalization#GO:0003002;multicellular organism development#GO:0007275;oogenesis#GO:0048477;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;camera-type eye morphogenesis#GO:0048593;negative regulation of macromolecule metabolic process#GO:0010605;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;camera-type eye development#GO:0043010 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004963.1|UniProtKB=W5MC68 W5MC68 PTHR23319:SF8 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-A cholesterol transfer activity#GO:0120020;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;cholesterol binding#GO:0015485 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;intracellular sterol transport#GO:0032366;establishment of localization in cell#GO:0051649;lipid localization#GO:0010876;intracellular transport#GO:0046907;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular lipid transport#GO:0032365 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016724.1|UniProtKB=W5NJ53 W5NJ53 PTHR46956:SF1 NUCLEOSIDE DIPHOSPHATE KINASE 6 NUCLEOSIDE DIPHOSPHATE KINASE 6 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 LEPOC|Ensembl=ENSLOCG00000004666.1|UniProtKB=W5MB32 W5MB32 PTHR22770:SF47 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF216 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010790.1|UniProtKB=W5MXW0 W5MXW0 PTHR12268:SF18 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROTELIN biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003458.1|UniProtKB=W5M6T7 W5M6T7 PTHR35349:SF4 DYNACTIN-ASSOCIATED PROTEIN CUPIN TYPE-1 DOMAIN-CONTAINING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008641.1|UniProtKB=W5MQ47 W5MQ47 GTPBP8 PTHR46498:SF1 GTP-BINDING PROTEIN 8 GTP-BINDING PROTEIN 8 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015134.1|UniProtKB=W5NDB7 W5NDB7 PTHR45686:SF1 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 vesicle targeting, to, from or within Golgi#GO:0048199;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;establishment of vesicle localization#GO:0051650;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;establishment of organelle localization#GO:0051656 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001260.1|UniProtKB=W5LZ68 W5LZ68 PTHR24104:SF55 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM71 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017644.1|UniProtKB=W5NM90 W5NM90 PTHR26451:SF869 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 530-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017362.1|UniProtKB=W5NLF8 W5NLF8 PTHR24228:SF55 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR 75-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017727.1|UniProtKB=W5NMH2 W5NMH2 PTHR17503:SF0 SYNCOLLIN SYNCOLLIN LEPOC|Ensembl=ENSLOCG00000011002.1|UniProtKB=W5MYN8 W5MYN8 PTHR35842:SF1 SI:CH211-67E16.11 SI:CH211-67E16.11 LEPOC|Ensembl=ENSLOCG00000002875.1|UniProtKB=W5M4S4 W5M4S4 PTHR24061:SF511 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000101.1|UniProtKB=W5LVF9 W5LVF9 PTHR11339:SF408 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-5B external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000009748.1|UniProtKB=W5MU74 W5MU74 PTHR11915:SF448 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006273.1|UniProtKB=W5MGS5 W5MGS5 PTHR12670:SF1 CERAMIDASE NEUTRAL CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;monocarboxylic acid metabolic process#GO:0032787;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000002964.1|UniProtKB=W5M535 W5M535 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005184.1|UniProtKB=W5MCY6 W5MCY6 PTHR23007:SF3 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL-B acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;aminoacyltransferase activity#GO:0016755;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;SH3 domain binding#GO:0017124;transferase activity#GO:0016740;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of protein kinase activity#GO:0006469;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of kinase activity#GO:0043549;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of ERBB signaling pathway#GO:1901184;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 ligase#PC00142;metabolite interconversion enzyme#PC00262 EGF receptor signaling pathway#P00018>c-Cbl#P00544 LEPOC|Ensembl=ENSLOCG00000012689.1|UniProtKB=W5N4Q7 W5N4Q7 OC90 PTHR11716:SF1 PHOSPHOLIPASE A2 FAMILY MEMBER OTOCONIN-90 cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000005919.1|UniProtKB=W5MFJ0 W5MFJ0 PTHR24391:SF28 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007358.1|UniProtKB=W5MKL1 W5MKL1 PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 LEPOC|Ensembl=ENSLOCG00000015105.1|UniProtKB=W5ND84 W5ND84 PTHR45994:SF3 FI21225P1 PROTEIN UNC-45 HOMOLOG A protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;Hsp90 protein binding#GO:0051879 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014422.1|UniProtKB=W5NAU7 W5NAU7 PTHR14485:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23 LEPOC|Ensembl=ENSLOCG00000003287.1|UniProtKB=W5M685 W5M685 PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;condensed chromosome#GO:0000793;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007722.1|UniProtKB=W5MLW3 W5MLW3 BMX PTHR24418:SF91 TYROSINE-PROTEIN KINASE CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;adaptive immune response#GO:0002250;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000017677.1|UniProtKB=W5NMC3 W5NMC3 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016633.1|UniProtKB=W5NIT5 W5NIT5 PTHR24240:SF56 OPSIN OPSIN 5-LIKE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002151.1|UniProtKB=W5M297 W5M297 PANK2 PTHR12280:SF25 PANTOTHENATE KINASE PANTOTHENATE KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000015328.1|UniProtKB=W5NE01 W5NE01 C2orf42 PTHR13518:SF1 PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER C2ORF42 HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015452.1|UniProtKB=W5NEF9 W5NEF9 PTHR28576:SF2 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014067.1|UniProtKB=W5N9N2 W5N9N2 PTHR48051:SF30 FAMILY NOT NAMED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014146.1|UniProtKB=W5N9W8 W5N9W8 PTHR46246:SF1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009746.1|UniProtKB=W5MU48 W5MU48 PTHR12303:SF6 CARNOSINE N-METHYLTRANSFERASE CARNOSINE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 LEPOC|Ensembl=ENSLOCG00000016814.1|UniProtKB=W5NJH0 W5NJH0 PTHR11723:SF5 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-2 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id2#P06804 LEPOC|Ensembl=ENSLOCG00000003708.1|UniProtKB=W5M7U8 W5M7U8 PTHR13251:SF3 EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000014851.1|UniProtKB=W5NCE0 W5NCE0 PTHR22870:SF155 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010517.1|UniProtKB=W5MWY1 W5MWY1 PTHR23351:SF52 FOS TRANSCRIPTION FACTOR-RELATED PROTO-ONCOGENE C-FOS-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000013925.1|UniProtKB=W5N956 W5N956 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005643.1|UniProtKB=W5MEK6 W5MEK6 PTHR15496:SF2 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011450.1|UniProtKB=W5N0A9 W5N0A9 PTHR12062:SF1 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005774.1|UniProtKB=W5MF17 W5MF17 RILPL1 PTHR21502:SF6 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010973.1|UniProtKB=W5MYT2 W5MYT2 PTHR45816:SF2 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR LEPOC|Ensembl=ENSLOCG00000008026.1|UniProtKB=W5MMZ2 W5MMZ2 PTHR13593:SF24 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 LEPOC|Ensembl=ENSLOCG00000006794.1|UniProtKB=W5MIJ7 W5MIJ7 PTHR43818:SF8 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003745.1|UniProtKB=W5M7X8 W5M7X8 PTHR10288:SF99 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001280.1|UniProtKB=W5LZ92 W5LZ92 PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;macromolecule localization#GO:0033036;maintenance of location#GO:0051235;organelle organization#GO:0006996;cellular component organization#GO:0016043;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular process#GO:0009987 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003021.1|UniProtKB=W5M5A0 W5M5A0 PTHR20982:SF3 RIBOSOME RECYCLING FACTOR MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001576.1|UniProtKB=W5M094 W5M094 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005200.1|UniProtKB=W5MD01 W5MD01 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L LEPOC|Ensembl=ENSLOCG00000015663.1|UniProtKB=W5NF73 W5NF73 PTHR10606:SF41 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;sugar-phosphatase activity#GO:0050308;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014659.1|UniProtKB=W5NBN3 W5NBN3 HEPH PTHR11709:SF233 MULTI-COPPER OXIDASE FERROXIDASE HEPHL1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017037.1|UniProtKB=W5NKA1 W5NKA1 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007338.1|UniProtKB=W5MKJ0 W5MKJ0 PTHR18945:SF929 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT PI signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003462.1|UniProtKB=W5M6U8 W5M6U8 PTHR28634:SF1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012810.1|UniProtKB=W5N551 W5N551 PTHR18945:SF82 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-6 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotine pharmacodynamics pathway#P06587>CHRNA6#P06592;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000018161.1|UniProtKB=W5NNQ3 W5NNQ3 PTHR22750:SF6 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007591.1|UniProtKB=W5MLF2 W5MLF2 PTHR24327:SF23 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008309.1|UniProtKB=W5MNY7 W5MNY7 PTHR23280:SF13 4.1 G PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MYLIP transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;organic substance catabolic process#GO:1901575;actin cytoskeleton organization#GO:0030036;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011493.1|UniProtKB=W5N0G1 W5N0G1 F2RL3 PTHR24232:SF22 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-4#P00461 LEPOC|Ensembl=ENSLOCG00000005125.1|UniProtKB=W5MCR7 W5MCR7 PTHR45706:SF5 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013095.1|UniProtKB=W5N673 W5N673 PTHR14217:SF1 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014521.1|UniProtKB=W5NB70 W5NB70 PTHR24416:SF66 TYROSINE-PROTEIN KINASE RECEPTOR NT-3 GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to endogenous stimulus#GO:0009719;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005451.1|UniProtKB=W5MDW7 W5MDW7 PTHR19308:SF53 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN CERAMIDE TRANSFER PROTEIN amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular lipid transport#GO:0032365 LEPOC|Ensembl=ENSLOCG00000016073.1|UniProtKB=W5NGP9 W5NGP9 GTSE1 PTHR21584:SF10 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 G2 AND S PHASE-EXPRESSED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>B99#G04697;p53 pathway#P00059>B99#P04613 LEPOC|Ensembl=ENSLOCG00000009455.1|UniProtKB=W5MT34 W5MT34 PTHR12345:SF14 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1 amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 LEPOC|Ensembl=ENSLOCG00000014774.1|UniProtKB=W5NC32 W5NC32 PTHR10485:SF2 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-B protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000526.1|UniProtKB=W5LWS1 W5LWS1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007379.1|UniProtKB=W5MKN9 W5MKN9 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004510.1|UniProtKB=W5MAI6 W5MAI6 PTHR10962:SF5 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2C amyloid-beta binding#GO:0001540;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013153.1|UniProtKB=W5N6E8 W5N6E8 PTHR13493:SF3 ZINC FINGER CCHC DOMAIN-CONTAINING RRNA N6-ADENOSINE-METHYLTRANSFERASE ZCCHC4 catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000015451.1|UniProtKB=W5NEG1 W5NEG1 PTHR24343:SF350 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002068.1|UniProtKB=W5M1Z3 W5M1Z3 PTHR15486:SF96 ANCIENT UBIQUITOUS PROTEIN LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012994.1|UniProtKB=W5N5V7 W5N5V7 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Sec5#P04545 LEPOC|Ensembl=ENSLOCG00000011099.1|UniProtKB=W5MZ27 W5MZ27 PTHR25462:SF291 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM45 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005000.1|UniProtKB=W5MCB2 W5MCB2 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000004112.1|UniProtKB=W5M955 W5M955 PTHR32341:SF10 INTERFERON-INDUCIBLE GTPASE INTERFERON-INDUCIBLE GTPASE 5 LEPOC|Ensembl=ENSLOCG00000002249.1|UniProtKB=W5M2L4 W5M2L4 C9orf64 PTHR21314:SF0 QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000001875.1|UniProtKB=W5M1C6 W5M1C6 PTHR24342:SF18 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001055.1|UniProtKB=W5LYL3 W5LYL3 PTHR15905:SF5 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1A cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012178.1|UniProtKB=W5N2W6 W5N2W6 ACTC1 PTHR11937:SF567 ACTIN ACTIN ALPHA CARDIAC MUSCLE 1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000005965.1|UniProtKB=W5MFP6 W5MFP6 PTHR12585:SF54 SCC1 / RAD21 FAMILY MEMBER RAD21 COHESIN COMPLEX COMPONENT LIKE 1 ISOFORM X1 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;sister chromatid cohesion#GO:0007062;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cohesin complex#GO:0008278;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010618.1|UniProtKB=W5MX91 W5MX91 PTHR35667:SF1 LEUKEMIA NUP98 FUSION PARTNER 1 LEUKEMIA NUP98 FUSION PARTNER 1 LEPOC|Ensembl=ENSLOCG00000015841.1|UniProtKB=W5NFU1 W5NFU1 CDHR3 PTHR24028:SF262 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000009183.1|UniProtKB=W5MS43 W5MS43 PTHR22829:SF18 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of hydrolase activity#GO:0051336;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002408.1|UniProtKB=W5M383 W5M383 PTHR13798:SF11 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA-BINDING PROTEIN 7-RELATED RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006954.1|UniProtKB=W5MJ49 W5MJ49 PTHR33968:SF1 PROTEIN PET100 HOMOLOG, MITOCHONDRIAL PROTEIN PET100 HOMOLOG, MITOCHONDRIAL protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015054.1|UniProtKB=W5ND17 W5ND17 PTHR10122:SF20 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002155.1|UniProtKB=W5M2A4 W5M2A4 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010267.1|UniProtKB=W5MW19 W5MW19 PTHR23322:SF57 FAS-ASSOCIATED PROTEIN SI:CH73-173P19.1 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008241.1|UniProtKB=W5MNP4 W5MNP4 PTHR13308:SF5 NEDD4-BINDING PROTEIN 2-LIKE 1 NEDD4-BINDING PROTEIN 2-LIKE 1 LEPOC|Ensembl=ENSLOCG00000017268.1|UniProtKB=W5NL51 W5NL51 PTHR10985:SF88 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;signaling#GO:0023052;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000006852.1|UniProtKB=W5MIS9 W5MIS9 PTHR13439:SF20 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 3A lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005581.1|UniProtKB=W5MED1 W5MED1 PTHR23257:SF707 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016855.1|UniProtKB=W5NJM7 W5NJM7 PTHR11616:SF280 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018008.1|UniProtKB=W5NNA0 W5NNA0 PTHR10270:SF113 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-11 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 sensory organ morphogenesis#GO:0090596;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;eye morphogenesis#GO:0048592;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;central nervous system development#GO:0007417;negative regulation of DNA-templated transcription#GO:0045892;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;negative regulation of metabolic process#GO:0009892;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;camera-type eye morphogenesis#GO:0048593;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000002458.1|UniProtKB=W5M3C9 W5M3C9 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B LEPOC|Ensembl=ENSLOCG00000012738.1|UniProtKB=W5N4W8 W5N4W8 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000001781.1|UniProtKB=W5M106 W5M106 PTHR10631:SF1 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRMT1-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000000878.1|UniProtKB=W5LXX6 W5LXX6 PTHR11453:SF127 ANION EXCHANGE PROTEIN SOLUTE CARRIER FAMILY 4 MEMBER 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017019.1|UniProtKB=W5NK79 W5NK79 PTHR43407:SF1 GLUTAMINE SYNTHETASE LENGSIN ligase activity#GO:0016874;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;response to extracellular stimulus#GO:0009991;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;L-amino acid metabolic process#GO:0170033;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;response to nutrient levels#GO:0031667;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;alpha-amino acid biosynthetic process#GO:1901607;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 LEPOC|Ensembl=ENSLOCG00000010963.1|UniProtKB=W5MYJ2 W5MYJ2 PTHR19325:SF570 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT COMPONENT 4 BINDING PROTEIN, MEMBRANE complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000000848.1|UniProtKB=W5LXU3 W5LXU3 PTHR11247:SF8 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013122.1|UniProtKB=W5N6A5 W5N6A5 PTHR25465:SF10 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018198.1|UniProtKB=W5NNU0 W5NNU0 PTHR23349:SF66 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST HOMLOG 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000005874.1|UniProtKB=W5MFD2 W5MFD2 PTHR10279:SF8 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 1 enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;positive regulation of catabolic process#GO:0009896;biological regulation#GO:0065007;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009653.1|UniProtKB=W5MTT7 W5MTT7 PTHR19871:SF39 BETA TRANSDUCIN-RELATED PROTEIN NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004241.1|UniProtKB=W5M9N9 W5M9N9 PTHR13723:SF39 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 15 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010982.1|UniProtKB=W5MYL4 W5MYL4 PTHR12442:SF34 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000001639.1|UniProtKB=W5M0H7 W5M0H7 PTHR28627:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013190.1|UniProtKB=W5N6J2 W5N6J2 PTHR10812:SF8 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013921.1|UniProtKB=W5N952 W5N952 HRH1 PTHR24248:SF204 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006604.1|UniProtKB=W5MHW9 W5MHW9 PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013194.1|UniProtKB=W5N6J5 W5N6J5 PTHR11506:SF2 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN MACROSIALIN localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002898.1|UniProtKB=W5M4U6 W5M4U6 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 LEPOC|Ensembl=ENSLOCG00000015170.1|UniProtKB=W5NDF9 W5NDF9 PTHR45740:SF14 POLY [ADP-RIBOSE] POLYMERASE NOVEL PROTEIN transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001760.1|UniProtKB=W5M0Y0 W5M0Y0 PTHR22883:SF417 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC20 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008514.1|UniProtKB=W5MPQ4 W5MPQ4 PTHR18945:SF883 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A-LIKE ISOFORM X1 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016898.1|UniProtKB=W5NJS8 W5NJS8 PTHR23119:SF58 DISCS LARGE LEUCINE RICH REPEAT CONTAINING 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 endosomal transport#GO:0016197;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;plasma membrane region#GO:0098590;postsynapse#GO:0098794;adherens junction#GO:0005912;basal part of cell#GO:0045178;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017535.1|UniProtKB=W5NLY1 W5NLY1 DIRAS2 PTHR24070:SF178 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005797.1|UniProtKB=W5MF43 W5MF43 C1QB PTHR15427:SF43 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT COMPONENT 1, Q SUBCOMPONENT, B CHAIN PRECURSOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004614.1|UniProtKB=W5MAW6 W5MAW6 PTHR23505:SF79 SPINSTER PROTEIN SPINSTER cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010989.1|UniProtKB=W5MYL8 W5MYL8 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003729.1|UniProtKB=W5M7S4 W5M7S4 PTHR14350:SF2 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000015963.1|UniProtKB=W5NG97 W5NG97 PTHR15835:SF6 NUCLEAR-INTERACTING PARTNER OF ALK ZINC FINGER C3HC-TYPE PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001029.1|UniProtKB=W5LYE6 W5LYE6 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017373.1|UniProtKB=W5NLG9 W5NLG9 PTHR24233:SF11 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 14-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011794.1|UniProtKB=W5N1J9 W5N1J9 PTHR45905:SF4 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005113.1|UniProtKB=W5MCP6 W5MCP6 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016485.1|UniProtKB=W5NIA5 W5NIA5 PTHR10272:SF0 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004138.1|UniProtKB=W5M985 W5M985 PTHR24249:SF387 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H2 RECEPTOR G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012001.1|UniProtKB=W5N2A1 W5N2A1 PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000006204.1|UniProtKB=W5MGI6 W5MGI6 PTHR13505:SF7 TRANSMEMBRANE PROTEIN 208 TRANSMEMBRANE PROTEIN 208 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013060.1|UniProtKB=W5N634 W5N634 PTHR12135:SF0 DNA REPAIR PROTEIN XP-C / RAD4 DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003738.1|UniProtKB=W5M7U3 W5M7U3 PTHR24322:SF736 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012936.1|UniProtKB=W5N5N3 W5N5N3 MYO1D PTHR13140:SF417 MYOSIN UNCONVENTIONAL MYOSIN-ID microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 actin filament-based movement#GO:0030048;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000008905.1|UniProtKB=W5MR48 W5MR48 RPL3L PTHR11363:SF7 60S RIBOSOMAL PROTEIN L3-RELATED RIBOSOMAL PROTEIN UL3-LIKE structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011222.1|UniProtKB=W5MZI1 W5MZI1 PTHR24343:SF306 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000003501.1|UniProtKB=W5M6Y5 W5M6Y5 PTHR21521:SF0 AMUN, ISOFORM A AMUN, ISOFORM A LEPOC|Ensembl=ENSLOCG00000001221.1|UniProtKB=W5LZ23 W5LZ23 PTHR19143:SF24 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013253.1|UniProtKB=W5N6R8 W5N6R8 PTHR15907:SF107 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000007568.1|UniProtKB=W5MLF6 W5MLF6 PTHR11199:SF6 STROMAL ANTIGEN COHESIN SUBUNIT SA-1 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cohesin complex#GO:0008278;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005287.1|UniProtKB=W5MDB7 W5MDB7 PTHR24223:SF10 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 12 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000698.1|UniProtKB=W5LXB5 W5LXB5 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004285.1|UniProtKB=W5M9R2 W5M9R2 PTHR10574:SF27 NETRIN/LAMININ-RELATED NETRIN-G2 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 LEPOC|Ensembl=ENSLOCG00000005821.1|UniProtKB=W5MF70 W5MF70 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013324.1|UniProtKB=W5N726 W5N726 PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011394.1|UniProtKB=W5N059 W5N059 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017829.1|UniProtKB=W5NMS3 W5NMS3 PTHR19290:SF88 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014099.1|UniProtKB=W5N9R9 W5N9R9 PTHR43195:SF3 TRANSKETOLASE TRANSKETOLASE cation binding#GO:0043169;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transketolase#PC00221;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Transketolase#P03082 LEPOC|Ensembl=ENSLOCG00000001191.1|UniProtKB=W5LYY2 W5LYY2 PTHR12620:SF8 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012516.1|UniProtKB=W5N452 W5N452 PTHR22975:SF5 UBIQUITIN SPECIFIC PROTEINASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 54 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012503.1|UniProtKB=W5N446 W5N446 PTHR22605:SF18 RZ-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF213-ALPHA transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;sprouting angiogenesis#GO:0002040;vasculature development#GO:0001944;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;circulatory system development#GO:0072359;negative regulation of response to stimulus#GO:0048585;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;tube development#GO:0035295;organonitrogen compound metabolic process#GO:1901564;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000004988.1|UniProtKB=W5MC94 W5MC94 PTHR10985:SF153 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of neuron differentiation#GO:0045664;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000002712.1|UniProtKB=W5M472 W5M472 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001155.1|UniProtKB=W5LYY1 W5LYY1 PTHR10407:SF14 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;actin binding#GO:0003779 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;cellular component biogenesis#GO:0044085;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;transport#GO:0006810;protein-containing complex assembly#GO:0065003;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;actin filament-based process#GO:0030029;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;regulation of proteolysis#GO:0030162;cellular component assembly#GO:0022607;positive regulation of catalytic activity#GO:0043085;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;actin cytoskeleton organization#GO:0030036;regulation of peptidase activity#GO:0052547;import into cell#GO:0098657;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;cortical cytoskeleton#GO:0030863;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-1#P00765 LEPOC|Ensembl=ENSLOCG00000008704.1|UniProtKB=W5MQD7 W5MQD7 PTHR11890:SF23 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR ACCESSORY PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of NF-kappaB transcription factor activity#GO:0051092;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016831.1|UniProtKB=W5NJJ6 W5NJJ6 PTHR23167:SF51 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006885.1|UniProtKB=W5MIW9 W5MIW9 PTHR22880:SF245 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 4 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009493.1|UniProtKB=W5MTA0 W5MTA0 PTHR24023:SF714 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;kidney development#GO:0001822;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011209.1|UniProtKB=W5MZG6 W5MZG6 PTHR11987:SF4 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8E transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007931.1|UniProtKB=W5MMM6 W5MMM6 PTHR11699:SF302 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE 2-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000013235.1|UniProtKB=W5N6P7 W5N6P7 PTHR18921:SF2 MYOSIN HEAVY CHAIN - RELATED THYROID RECEPTOR-INTERACTING PROTEIN 11 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000005775.1|UniProtKB=W5MF15 W5MF15 PTHR21500:SF0 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000017632.1|UniProtKB=W5NM78 W5NM78 PTHR16736:SF3 CORTEXIN-1-RELATED CORTEXIN-1 LEPOC|Ensembl=ENSLOCG00000000020.1|UniProtKB=W5LV65 W5LV65 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001361.1|UniProtKB=W5LZI3 W5LZI3 TMED6 PTHR22811:SF45 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 6 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000002158.1|UniProtKB=W5M2C1 W5M2C1 PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000003123.1|UniProtKB=W5M5L9 W5M5L9 PTHR11640:SF158 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009756.1|UniProtKB=W5MU69 W5MU69 PTHR13817:SF49 TITIN MYOSIN-BINDING PROTEIN H sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008981.1|UniProtKB=W5MRD8 W5MRD8 PTHR21437:SF2 WIDE AWAKE ANKYRIN REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 1-LIKE establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000420.1|UniProtKB=W5LWF6 W5LWF6 PTHR18966:SF377 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1 signaling receptor activity#GO:0038023;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR1#P01010;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 LEPOC|Ensembl=ENSLOCG00000010318.1|UniProtKB=J3AMA0 J3AMA0 AgRP2 PTHR16551:SF5 AGOUTI RELATED AGOUTI-RELATED PEPTIDE 2 neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;behavior#GO:0007610;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013371.1|UniProtKB=W5N774 W5N774 PTHR18884:SF47 SEPTIN SEPTIN-9 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011016.1|UniProtKB=W5MYR5 W5MYR5 PTHR24418:SF90 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE YES protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Yes#P00476;CCKR signaling map#P06959>YES1#P07142;Parkinson disease#P00049>Src kinase#P01230 LEPOC|Ensembl=ENSLOCG00000015197.1|UniProtKB=W5NDJ6 W5NDJ6 PTHR17695:SF11 SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000002762.1|UniProtKB=W5M4E1 W5M4E1 PTHR45476:SF5 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL 4-RELATED ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011267.1|UniProtKB=W5MZN6 W5MZN6 PTHR23172:SF34 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED CYCLIN-G-ASSOCIATED KINASE protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;protein-containing complex organization#GO:0043933;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018138.1|UniProtKB=W5NNN0 W5NNN0 PTHR22650:SF7 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IB BETA CHAIN Blood coagulation#P00011>GP 1bbeta#P00436 LEPOC|Ensembl=ENSLOCG00000004927.1|UniProtKB=W5MC15 W5MC15 PTHR31334:SF1 SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8 guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000000630.1|UniProtKB=W5LX38 W5LX38 PTHR34766:SF1 UPF0449 PROTEIN C19ORF25 UPF0449 PROTEIN C19ORF25 LEPOC|Ensembl=ENSLOCG00000016722.1|UniProtKB=W5NJ50 W5NJ50 PTHR14731:SF1 BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN BAALC BINDER OF MAP3K1 AND KLF4 B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018229.1|UniProtKB=W5NNX1 W5NNX1 PTHR23506:SF13 GH10249P VESICULAR ACETYLCHOLINE TRANSPORTER transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;terminal bouton#GO:0043195;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;axon terminus#GO:0043679;membrane coat#GO:0030117;neuron projection terminus#GO:0044306;distal axon#GO:0150034;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;trans-Golgi network transport vesicle#GO:0030140;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell junction#GO:0030054;cell periphery#GO:0071944;coated vesicle#GO:0030135;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;vesicle coat#GO:0030120;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;neuron projection#GO:0043005;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065 LEPOC|Ensembl=ENSLOCG00000006491.1|UniProtKB=W5MHI7 W5MHI7 TSR1 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG snoRNA binding#GO:0030515;GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 preribosome, small subunit precursor#GO:0030688;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000001715.1|UniProtKB=W5M0S8 W5M0S8 PTHR22896:SF1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015412.1|UniProtKB=W5NEA6 W5NEA6 PTHR11515:SF11 GLYCOPROTEIN HORMONE BETA CHAIN LUTROPIN SUBUNIT BETA regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#P06751;Gonadotropin-releasing hormone receptor pathway#P06664>5' LHbeta#G06889;Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#G06688;Gonadotropin-releasing hormone receptor pathway#P06664>3' LHbeta#G06903 LEPOC|Ensembl=ENSLOCG00000006315.1|UniProtKB=W5MGW7 W5MGW7 PTHR23037:SF34 CYTOKINE RECEPTOR THROMBOPOIETIN RECEPTOR ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002746.1|UniProtKB=W5M4C6 W5M4C6 PTHR10730:SF9 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER INACTIVE GLYCOSYLTRANSFERASE 25 FAMILY MEMBER 3 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013612.1|UniProtKB=W5N822 W5N822 PTHR11371:SF26 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000011559.1|UniProtKB=W5N0P6 W5N0P6 PTHR11977:SF87 VILLIN SUPERVILLIN ISOFORM X1 cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000000791.1|UniProtKB=W5LXM3 W5LXM3 PTHR11626:SF2 FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE SQUALENE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;isoprenoid metabolic process#GO:0006720;phosphorus metabolic process#GO:0006793;terpenoid metabolic process#GO:0006721;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Farnesyl-diphosphate farnesyltransferase#P00499 LEPOC|Ensembl=ENSLOCG00000009323.1|UniProtKB=W5MSL9 W5MSL9 PTHR14690:SF10 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 IQ AND AAA DOMAIN-CONTAINING PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000013885.1|UniProtKB=W5N914 W5N914 PTHR10281:SF23 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012652.1|UniProtKB=W5N4L2 W5N4L2 PTHR12173:SF1 GDNF SUBFAMILY OF TGF-BETA FAMILY GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;multicellular organism development#GO:0007275;peripheral nervous system development#GO:0007422;nervous system development#GO:0007399;positive regulation of developmental process#GO:0051094;negative regulation of apoptotic process#GO:0043066;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240;regulation of programmed cell death#GO:0043067 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 neurotrophic factor#PC00163;growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000004248.1|UniProtKB=W5M9L7 W5M9L7 PTHR10219:SF97 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002209.1|UniProtKB=W5M2F7 W5M2F7 PTHR46006:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A DH DOMAIN-CONTAINING PROTEIN regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013451.1|UniProtKB=W5N7H2 W5N7H2 PTHR46166:SF2 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-B8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014640.1|UniProtKB=W5NBL6 W5NBL6 PTHR23281:SF26 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 microvillus#GO:0005902;filopodium#GO:0030175;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;actin-based cell projection#GO:0098858;adherens junction#GO:0005912;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008874.1|UniProtKB=W5MQZ4 W5MQZ4 PTHR10560:SF0 THROMBOPOIETIN THROMBOPOIETIN LEPOC|Ensembl=ENSLOCG00000006017.1|UniProtKB=W5MFW5 W5MFW5 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248 oxidase#PC00175;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000007477.1|UniProtKB=W5ML15 W5ML15 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015718.1|UniProtKB=W5NFD9 W5NFD9 PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009449.1|UniProtKB=W5MT25 W5MT25 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN BETA-MICROSEMINOPROTEIN intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015675.1|UniProtKB=W5NF85 W5NF85 PTHR10201:SF323 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000001881.1|UniProtKB=W5M1C4 W5M1C4 PTHR43128:SF33 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006380.1|UniProtKB=W5MH64 W5MH64 TMEM132C PTHR13388:SF4 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C LEPOC|Ensembl=ENSLOCG00000003153.1|UniProtKB=W5M5R5 W5M5R5 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009466.1|UniProtKB=W5MT48 W5MT48 ADGRG7 PTHR12011:SF305 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005168.1|UniProtKB=W5MCX0 W5MCX0 PTHR23280:SF18 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4B cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003801.1|UniProtKB=W5M833 W5M833 PTHR24391:SF26 HISTONE H4 TRANSCRIPTION FACTOR-RELATED HISTONE H4 TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007604.1|UniProtKB=W5MLG7 W5MLG7 PTHR32463:SF0 L-FUCOSE KINASE L-FUCOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000014722.1|UniProtKB=W5NBW5 W5NBW5 PTHR11984:SF20 CONNEXIN GAP JUNCTION BETA-1 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000002094.1|UniProtKB=W5M239 W5M239 PTHR47977:SF73 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002866.1|UniProtKB=W5M4R8 W5M4R8 PTHR10554:SF8 SYNTROPHIN BETA-2-SYNTROPHIN membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002059.1|UniProtKB=W5M1Y1 W5M1Y1 PTHR24256:SF570 TRYPTASE-RELATED CLIP-DOMAIN SERINE PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011689.1|UniProtKB=W5N159 W5N159 PTHR11267:SF32 T-BOX PROTEIN-RELATED MAX GENE-ASSOCIATED PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000002730.1|UniProtKB=W5M4A4 W5M4A4 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000399.1|UniProtKB=W5LWD0 W5LWD0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002210.1|UniProtKB=W5M2G9 W5M2G9 PTHR11142:SF0 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000006776.1|UniProtKB=W5MIH5 W5MIH5 PTHR23424:SF23 SERUM AMYLOID A PROTEIN SAAL1 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002680.1|UniProtKB=W5M436 W5M436 PTHR47980:SF35 LD44762P RAS-RELATED PROTEIN RAB-12 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015156.1|UniProtKB=W5NDE3 W5NDE3 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013690.1|UniProtKB=W5N8B7 W5N8B7 PTHR43048:SF3 METHYLMALONYL-COA EPIMERASE METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 epimerase/racemase#PC00096 Methylmalonyl pathway#P02755>Methylmalonyl-CoA epimerase#P03032 LEPOC|Ensembl=ENSLOCG00000003147.1|UniProtKB=W5M5S0 W5M5S0 PTHR13140:SF289 MYOSIN UNCONVENTIONAL MYOSIN-XIX microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000017810.1|UniProtKB=W5NMQ5 W5NMQ5 PTHR24390:SF256 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 711 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013776.1|UniProtKB=W5N8N3 W5N8N3 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015571.1|UniProtKB=W5NEW3 W5NEW3 PTHR11227:SF29 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006264.1|UniProtKB=W5MGR1 W5MGR1 PTHR14234:SF18 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 2 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;neuromuscular synaptic transmission#GO:0007274;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002109.1|UniProtKB=W5M245 W5M245 PTHR11636:SF81 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011156.1|UniProtKB=W5MZ99 W5MZ99 PTHR12207:SF21 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016293.1|UniProtKB=W5NHJ8 W5NHJ8 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000006169.1|UniProtKB=W5MGE2 W5MGE2 PTHR10224:SF5 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE LIKE CLASS 1 DOMAIN CONTAINING 3A-LIKE1-RELATED LEPOC|Ensembl=ENSLOCG00000004205.1|UniProtKB=W5M9G5 W5M9G5 MTIF3 PTHR10938:SF0 TRANSLATION INITIATION FACTOR IF-3 TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;cellular process#GO:0009987;organelle organization#GO:0006996;organelle disassembly#GO:1903008 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013953.1|UniProtKB=W5N994 W5N994 PTHR47130:SF1 SI:DKEY-19B23.11-RELATED ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004608.1|UniProtKB=W5MAW9 W5MAW9 PTHR24178:SF21 MOLTING PROTEIN MLT-4 ANKYRIN REPEAT DOMAIN 52-RELATED protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;regulation of multicellular organismal process#GO:0051239;macromolecule localization#GO:0033036;regulation of muscle contraction#GO:0006937;regulation of heart contraction#GO:0008016;protein localization to membrane#GO:0072657;regulation of system process#GO:0044057;cellular process#GO:0009987;protein localization#GO:0008104;regulation of muscle system process#GO:0090257;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of biological process#GO:0050789;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;biological regulation#GO:0065007;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000790.1|UniProtKB=W5LXN0 W5LXN0 PTHR46806:SF4 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;vascular endothelial growth factor receptor signaling pathway#GO:0048010;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;positive regulation of locomotion#GO:0040017;tube development#GO:0035295;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to wounding#GO:0009611;angiogenesis#GO:0001525;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;vasculogenesis#GO:0001570;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of filopodium assembly#GO:0051489;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;cell development#GO:0048468;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of cell projection assembly#GO:0060491;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;generation of neurons#GO:0048699;cell migration#GO:0016477 anchoring junction#GO:0070161;neuron projection#GO:0043005;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;plasma membrane#GO:0005886 Axon guidance mediated by semaphorins#P00007>Neuropilin 1#P00338 LEPOC|Ensembl=ENSLOCG00000005731.1|UniProtKB=W5MEW1 W5MEW1 PTHR21580:SF57 SHIPPO-1-RELATED OUTER DENSE FIBER OF SPERM TAILS 3-LIKE 2-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012877.1|UniProtKB=W5N5E3 W5N5E3 PTHR10511:SF2 GRANULOCYTE COLONY-STIMULATING FACTOR GRANULOCYTE COLONY-STIMULATING FACTOR LEPOC|Ensembl=ENSLOCG00000015827.1|UniProtKB=W5NFS3 W5NFS3 PRKAR2B PTHR11635:SF156 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT protein kinase A binding#GO:0051018;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570 LEPOC|Ensembl=ENSLOCG00000001987.1|UniProtKB=W5M1Q1 W5M1Q1 PTHR24271:SF47 KALLIKREIN-RELATED KALLIKREIN-1 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007995.1|UniProtKB=W5MMV8 W5MMV8 PTHR10110:SF90 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 3 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007156.1|UniProtKB=W5MJX0 W5MJX0 PTHR14240:SF1 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN PROTEIN FANTOM-RELATED organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018023.1|UniProtKB=W5NNB5 W5NNB5 PTHR24072:SF158 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;Rac protein signal transduction#GO:0016601;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of organelle organization#GO:0033043;cell communication#GO:0007154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;cell chemotaxis#GO:0060326;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Rac#P00564;Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834 LEPOC|Ensembl=ENSLOCG00000011364.1|UniProtKB=W5N007 W5N007 PTHR22929:SF0 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011868.1|UniProtKB=W5N1T2 W5N1T2 PTHR46260:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8A LEPOC|Ensembl=ENSLOCG00000014848.1|UniProtKB=W5NCC5 W5NCC5 PTHR24347:SF372 SERINE/THREONINE-PROTEIN KINASE DEATH ASSOCIATED PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015543.1|UniProtKB=W5NES3 W5NES3 PTHR35578:SF6 PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED PROLINE-RICH TRANSMEMBRANE PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000015928.1|UniProtKB=W5NG51 W5NG51 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007425.1|UniProtKB=W5MKV6 W5MKV6 PTHR10027:SF9 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion-gated channel activity#GO:0022839;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000692.1|UniProtKB=W5LXB2 W5LXB2 PTHR21685:SF1 TON-B BOX DOMAIN TAPERIN LEPOC|Ensembl=ENSLOCG00000009325.1|UniProtKB=W5MSM2 W5MSM2 PTHR35971:SF5 SI:DKEY-31G6.6 OBSCURIN LIKE CYTOSKELETAL ADAPTOR 1 LEPOC|Ensembl=ENSLOCG00000000061.1|UniProtKB=W5LVB4 W5LVB4 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005456.1|UniProtKB=W5MDX0 W5MDX0 PTHR46484:SF3 SI:CH211-171H4.5-RELATED MYELIN-ASSOCIATED GLYCOPROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000015247.1|UniProtKB=W5NDQ6 W5NDQ6 PTHR11523:SF12 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT PROTEIN ATP1B4 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;regulation of nitrogen compound metabolic process#GO:0051171;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;regulation of RNA biosynthetic process#GO:2001141;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;monoatomic cation transport#GO:0006812;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of DNA-templated transcription#GO:0006355;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;regulation of RNA metabolic process#GO:0051252;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;sodium ion transport#GO:0006814;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;regulation of metabolic process#GO:0019222;sodium ion transmembrane transport#GO:0035725;regulation of cellular metabolic process#GO:0031323;potassium ion import across plasma membrane#GO:1990573 envelope#GO:0031975;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear inner membrane#GO:0005637;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006728.1|UniProtKB=W5MIC2 W5MIC2 PTHR44461:SF1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011140.1|UniProtKB=W5MZ80 W5MZ80 PTHR18966:SF361 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2C transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated channel activity#GO:0022832;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 signal transduction#GO:0007165;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of postsynaptic membrane potential#GO:0060078;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 LEPOC|Ensembl=ENSLOCG00000013247.1|UniProtKB=W5N6R5 W5N6R5 MPDZ PTHR19964:SF10 MULTIPLE PDZ DOMAIN PROTEIN MULTIPLE PDZ DOMAIN PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;apical junction complex#GO:0043296 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010383.1|UniProtKB=W5MWH1 W5MWH1 PTHR14038:SF6 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2C cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006581.1|UniProtKB=W5MHT7 W5MHT7 PTHR13603:SF1 TRANSMEMBRANE PROTEIN 186 TRANSMEMBRANE PROTEIN 186 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003997.1|UniProtKB=A0A075B5H9 A0A075B5H9 PTHR46385:SF3 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>Prx2#P06731 LEPOC|Ensembl=ENSLOCG00000007872.1|UniProtKB=W5MMF1 W5MMF1 PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005645.1|UniProtKB=W5MEL2 W5MEL2 PTHR31078:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013515.1|UniProtKB=W5N7Q8 W5N7Q8 PTHR24173:SF1 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 33B scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010998.1|UniProtKB=W5MYN5 W5MYN5 COQ6 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012130.1|UniProtKB=W5N2R4 W5N2R4 PTHR24412:SF179 KELCH PROTEIN KELCH-LIKE PROTEIN 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010455.1|UniProtKB=W5MWS9 W5MWS9 PTHR11908:SF86 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002926.1|UniProtKB=W5M4Y8 W5M4Y8 PTHR11157:SF126 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000011334.1|UniProtKB=W5MZX5 W5MZX5 PTHR10877:SF196 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;sodium ion transmembrane transporter activity#GO:0015081;small molecule binding#GO:0036094;binding#GO:0005488;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;ligand-gated monoatomic cation channel activity#GO:0099094;ion binding#GO:0043167;sodium channel activity#GO:0005272;monoatomic ion transmembrane transporter activity#GO:0015075;calcium ion transmembrane transporter activity#GO:0015085;cytoskeletal protein binding#GO:0008092;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;metal ion binding#GO:0046872;channel activity#GO:0015267;transporter activity#GO:0005215;cation binding#GO:0043169;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;protein binding#GO:0005515;calcium ion binding#GO:0005509;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 detection of mechanical stimulus#GO:0050982;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;detection of stimulus#GO:0051606;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to mechanical stimulus#GO:0009612;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;response to abiotic stimulus#GO:0009628;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014431.1|UniProtKB=W5NAV3 W5NAV3 PTHR13440:SF7 BLOC-1 RELATED COMPLEX SUBUNIT 6 BLOC-1 RELATED COMPLEX SUBUNIT 6 lysosome localization#GO:0032418;localization#GO:0051179;organelle localization#GO:0051640 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000017464.1|UniProtKB=W5NLR0 W5NLR0 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014759.1|UniProtKB=W5NC15 W5NC15 PTHR10071:SF190 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ERYTHROID TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004736.1|UniProtKB=W5MBB5 W5MBB5 PTHR11767:SF106 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007643.1|UniProtKB=W5MLL1 W5MLL1 PTHR21603:SF17 ANTIGEN KI-67-LIKE PROTEIN PROLIFERATION MARKER PROTEIN KI-67 regulation of biological process#GO:0050789;regulation of mitotic nuclear division#GO:0007088;regulation of nuclear division#GO:0051783;regulation of chromosome segregation#GO:0051983;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle process#GO:0010564 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007828.1|UniProtKB=W5MMC5 W5MMC5 PTHR23140:SF10 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP DOMAIN-CONTAINING nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000015464.1|UniProtKB=W5NEH1 W5NEH1 PTHR19879:SF6 TRANSCRIPTION INITIATION FACTOR TFIID TAF5-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;DNA-directed RNA polymerase complex#GO:0000428;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005299.1|UniProtKB=W5MDC1 W5MDC1 PTHR11955:SF150 FATTY ACID BINDING PROTEIN ADIPOCYTE FATTY ACID-BINDING PROTEIN-RELATED fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015416.1|UniProtKB=W5NEB4 W5NEB4 PTHR12191:SF5 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP14 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009664.1|UniProtKB=W5MTV5 W5MTV5 PTHR11819:SF96 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009350.1|UniProtKB=W5MSP6 W5MSP6 PTHR24334:SF2 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007293.1|UniProtKB=W5MKC6 W5MKC6 MID1 PTHR24099:SF23 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013389.1|UniProtKB=W5N796 W5N796 PTHR25466:SF3 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 1 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014649.1|UniProtKB=W5NBM3 W5NBM3 PTHR23179:SF36 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO-GAP DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016503.1|UniProtKB=W5NIC9 W5NIC9 PTHR11685:SF448 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE PARKIN ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;autophagy of mitochondrion#GO:0000422;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of mitochondrion organization#GO:0010821;proteolysis#GO:0006508;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;cellular catabolic process#GO:0044248;regulation of apoptotic process#GO:0042981;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organelle disassembly#GO:1903008;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Parkin#P01216 LEPOC|Ensembl=ENSLOCG00000015706.1|UniProtKB=W5NFC6 W5NFC6 PTHR15298:SF19 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006787.1|UniProtKB=W5MIJ2 W5MIJ2 PTHR46152:SF1 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000012865.1|UniProtKB=W5N5C6 W5N5C6 PTHR22990:SF15 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 10 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002847.1|UniProtKB=W5M4P3 W5M4P3 PTHR23288:SF37 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN_ELL DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell junction assembly#GO:0034329;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;cell-cell junction organization#GO:0045216;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;cell-cell junction assembly#GO:0007043;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;tight junction#GO:0070160;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;apical junction complex#GO:0043296;plasma membrane#GO:0005886 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000000462.1|UniProtKB=W5LWJ7 W5LWJ7 PTHR23411:SF41 TAPASIN IG KAPPA-B4 CHAIN C REGION immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007318.1|UniProtKB=W5MKF6 W5MKF6 PTHR11673:SF6 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-RELATED nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012469.1|UniProtKB=W5N3Z7 W5N3Z7 PTHR43391:SF15 RETINOL DEHYDROGENASE-RELATED 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;estradiol 17-beta-dehydrogenase [NAD(P)] activity#GO:0004303;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid metabolic process#GO:0006629;hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 LEPOC|Ensembl=ENSLOCG00000011052.1|UniProtKB=W5MYW8 W5MYW8 PTHR19853:SF0 WD REPEAT CONTAINING PROTEIN 3 WDR3 WD REPEAT-CONTAINING PROTEIN 3 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000017275.1|UniProtKB=W5NL59 W5NL59 AKAP7 PTHR15934:SF6 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7 ISOFORM GAMMA protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008006.1|UniProtKB=W5MMW2 W5MMW2 PTHR11132:SF293 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E4 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013634.1|UniProtKB=W5N848 W5N848 PTHR12025:SF3 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR C molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;response to abiotic stimulus#GO:0009628;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to hypoxia#GO:0001666;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;positive regulation of leukocyte migration#GO:0002687;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of immune system process#GO:0002682;signaling#GO:0023052;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of response to external stimulus#GO:0032101;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of leukocyte chemotaxis#GO:0002690 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000011049.1|UniProtKB=W5MYW0 W5MYW0 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of transcription by RNA polymerase I#GO:0045943;cellular component biogenesis#GO:0044085;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;regulation of transcription by RNA polymerase I#GO:0006356;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004679.1|UniProtKB=W5MB43 W5MB43 PTHR10104:SF18 STATHMIN STATHMIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;distal axon#GO:0150034;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014108.1|UniProtKB=W5N9S2 W5N9S2 PTHR16290:SF4 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000010698.1|UniProtKB=W5MXJ8 W5MXJ8 PTHR18945:SF514 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008826.1|UniProtKB=W5MQS7 W5MQS7 PTHR11848:SF150 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 8 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000008959.1|UniProtKB=W5MRA2 W5MRA2 PTHR24409:SF298 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 142 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017081.1|UniProtKB=W5NKF0 W5NKF0 RWDD2A PTHR15955:SF3 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2A ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012803.1|UniProtKB=W5N546 W5N546 PTHR18945:SF75 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-3 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotine pharmacodynamics pathway#P06587>CHRNB3#P06612 LEPOC|Ensembl=ENSLOCG00000016261.1|UniProtKB=W5NHE5 W5NHE5 PTHR10334:SF220 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIPR1-LIKE PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014925.1|UniProtKB=W5NCM0 W5NCM0 PTHR24279:SF3 CYTOCHROME P450 CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, MITOCHONDRIAL sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;response to peptide hormone#GO:0043434;cholesterol metabolic process#GO:0008203;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699;steroid metabolic process#GO:0008202;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biological quality#GO:0065008;secondary alcohol metabolic process#GO:1902652;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;hormone biosynthetic process#GO:0042446;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular response to peptide#GO:1901653;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;hormone metabolic process#GO:0042445;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010823.1|UniProtKB=W5MY14 W5MY14 PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 LEPOC|Ensembl=ENSLOCG00000017883.1|UniProtKB=W5NMX7 W5NMX7 PTHR31815:SF0 AGAP005329-PA TRANSMEMBRANE PROTEIN 200A LEPOC|Ensembl=ENSLOCG00000012735.1|UniProtKB=W5N4W0 W5N4W0 PTHR13563:SF19 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG B tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000009986.1|UniProtKB=W5MV03 W5MV03 NSG1 PTHR28546:SF3 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;transport#GO:0006810;protein-containing complex assembly#GO:0065003;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012812.1|UniProtKB=W5N553 W5N553 PTHR21514:SF0 AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016423.1|UniProtKB=W5NI27 W5NI27 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000007054.1|UniProtKB=W5MJH7 W5MJH7 PTHR11132:SF247 SOLUTE CARRIER FAMILY 35 NUCLEOTIDE SUGAR TRANSPORTER SLC35D1 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007583.1|UniProtKB=W5MLE5 W5MLE5 PTHR12474:SF4 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-3 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of metabolic process#GO:0009893;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;positive regulation of macroautophagy#GO:0016239;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009900.1|UniProtKB=W5MUP0 W5MUP0 PTHR12893:SF2 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 1 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014973.1|UniProtKB=W5NCS8 W5NCS8 PTHR24083:SF4 NUCLEAR HORMONE RECEPTOR PHOTORECEPTOR-SPECIFIC NUCLEAR RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002513.1|UniProtKB=W5M3J6 W5M3J6 PTHR24291:SF5 CYTOCHROME P450 FAMILY 4 1,25-DIHYDROXYVITAMIN D(3) 24-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid catabolic process#GO:0006706;response to organic cyclic compound#GO:0014070;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to lipid#GO:0033993;response to nutrient levels#GO:0031667;lipid catabolic process#GO:0016042;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;small molecule catabolic process#GO:0044282;organic cyclic compound metabolic process#GO:1901360;response to chemical#GO:0042221;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>24-Hydroxylase#G04688;Vitamin D metabolism and pathway#P04396>24-Hydroxylase#P04608 LEPOC|Ensembl=ENSLOCG00000016032.1|UniProtKB=W5NGJ0 W5NGJ0 PTHR11937:SF37 ACTIN ACTIN-RELATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470 LEPOC|Ensembl=ENSLOCG00000011647.1|UniProtKB=W5N106 W5N106 PTHR11920:SF347 GUANYLYL CYCLASE GUANYLYL CYCLASE C adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000006341.1|UniProtKB=W5MGZ9 W5MGZ9 PTHR40446:SF2 N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE LEPOC|Ensembl=ENSLOCG00000015052.1|UniProtKB=W5ND14 W5ND14 PTHR28674:SF1 SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED NOP PROTEIN CHAPERONE 1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000016810.1|UniProtKB=W5NJG8 W5NJG8 PTHR21339:SF0 RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 S-ADENOSYLMETHIONINE-DEPENDENT NUCLEOTIDE DEHYDRATASE RSAD2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 LEPOC|Ensembl=ENSLOCG00000006071.1|UniProtKB=W5MG21 W5MG21 PTHR22883:SF301 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC12 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012100.1|UniProtKB=W5N2M6 W5N2M6 PTHR14235:SF0 OSTEOCALCIN OSTEOCALCIN structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;ossification#GO:0001503;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;osteoblast differentiation#GO:0001649;multicellular organismal process#GO:0032501;skeletal system development#GO:0001501;cellular process#GO:0009987;bone development#GO:0060348 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000016762.1|UniProtKB=W5NJB1 W5NJB1 PTHR42687:SF4 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;aspartate family amino acid metabolic process#GO:0009066;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008230.1|UniProtKB=W5MNM8 W5MNM8 PTHR13308:SF23 NEDD4-BINDING PROTEIN 2-LIKE 1 NEDD4-BINDING PROTEIN 2-LIKE 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001693.1|UniProtKB=W5M0Q6 W5M0Q6 PTHR10747:SF36 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000007332.1|UniProtKB=W5MKG9 W5MKG9 PTHR19446:SF479 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000006034.1|UniProtKB=W5MFX9 W5MFX9 PTHR11627:SF3 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE C lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aldolase#PC00044;lyase#PC00144 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 LEPOC|Ensembl=ENSLOCG00000000496.1|UniProtKB=W5LWP1 W5LWP1 PTHR24393:SF151 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009838.1|UniProtKB=W5MUG7 W5MUG7 AMN PTHR14995:SF2 AMNIONLESS PROTEIN AMNIONLESS localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657;protein localization#GO:0008104 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014840.1|UniProtKB=W5NCB5 W5NCB5 PTHR10390:SF65 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005657.1|UniProtKB=W5MEN0 W5MEN0 PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;nitrogen compound metabolic process#GO:0006807;synaptic signaling#GO:0099536;biological regulation#GO:0065007;neuromuscular synaptic transmission#GO:0007274;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 LEPOC|Ensembl=ENSLOCG00000003059.1|UniProtKB=W5M5E4 W5M5E4 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED SI:CH211-113E8.5 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000017657.1|UniProtKB=W5NMA3 W5NMA3 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014320.1|UniProtKB=W5NAI1 W5NAI1 PTHR11915:SF425 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 muscle structure development#GO:0061061;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;Z disc#GO:0030018;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cortical actin cytoskeleton#GO:0030864;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cell projection#GO:0042995;cytoskeleton#GO:0005856;myofibril#GO:0030016;plasma membrane#GO:0005886;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000007911.1|UniProtKB=W5MML0 W5MML0 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000012753.1|UniProtKB=W5N4Y8 W5N4Y8 PTHR23055:SF65 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 2 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017202.1|UniProtKB=W5NKV6 W5NKV6 PTHR13390:SF0 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE localization#GO:0051179;lipid localization#GO:0010876;lipid storage#GO:0019915;macromolecule localization#GO:0033036;maintenance of location#GO:0051235 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014791.1|UniProtKB=W5NC65 W5NC65 PTHR13720:SF50 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000957.1|UniProtKB=W5LY66 W5LY66 PTHR46831:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 cytoplasm#GO:0005737;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005224.1|UniProtKB=W5MD45 W5MD45 PTHR42840:SF3 NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010967.1|UniProtKB=W5MYM3 W5MYM3 PTHR11782:SF35 ADENOSINE/GUANOSINE DIPHOSPHATASE NUCLEOSIDE DIPHOSPHATE PHOSPHATASE ENTPD5 metabolite interconversion enzyme#PC00262;nucleotide phosphatase#PC00173;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000006612.1|UniProtKB=W5MI04 W5MI04 PTHR46377:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;regulation of MAP kinase activity#GO:0043405;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000008661.1|UniProtKB=W5MQ79 W5MQ79 PTHR10110:SF196 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012026.1|UniProtKB=W5N2D8 W5N2D8 PTHR22699:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005548.1|UniProtKB=W5ME85 W5ME85 PTHR11818:SF8 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A3 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003334.1|UniProtKB=W5M6D2 W5M6D2 PTHR46661:SF2 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013390.1|UniProtKB=W5N795 W5N795 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 19 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>TCR Beta#P01299 LEPOC|Ensembl=ENSLOCG00000009541.1|UniProtKB=W5MTF2 W5MTF2 PTHR45638:SF19 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;protein-containing complex binding#GO:0044877;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003358.1|UniProtKB=W5M6G7 W5M6G7 PTHR11034:SF21 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG4 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signaling#GO:0023056;signaling#GO:0023052;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006005.1|UniProtKB=W5MFV2 W5MFV2 PTHR10681:SF111 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-1 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cellular process#GO:0009987;cell activation#GO:0001775;immune system process#GO:0002376;response to stimulus#GO:0050896;detoxification#GO:0098754;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;response to toxic substance#GO:0009636;response to reactive oxygen species#GO:0000302;cellular response to stress#GO:0033554;leukocyte activation#GO:0045321;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002321.1|UniProtKB=W5M2W6 W5M2W6 PTHR10546:SF1 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL SUBUNIT BETA-3 protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;blood circulation#GO:0008015;regulation of sodium ion transport#GO:0002028;actin filament-based movement#GO:0030048;regulation of metal ion transport#GO:0010959;system process#GO:0003008;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000011275.1|UniProtKB=W5MZP5 W5MZP5 PTHR24328:SF1 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008087.1|UniProtKB=W5MN63 W5MN63 PTHR12533:SF6 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;calcineurin-mediated signaling#GO:0097720;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367 LEPOC|Ensembl=ENSLOCG00000011539.1|UniProtKB=W5N0L9 W5N0L9 PTHR22957:SF570 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2A nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000017557.1|UniProtKB=W5NM03 W5NM03 PTHR24237:SF36 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 3-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013898.1|UniProtKB=W5N927 W5N927 PTHR15837:SF0 RAN GUANINE NUCLEOTIDE RELEASE FACTOR RAN GUANINE NUCLEOTIDE RELEASE FACTOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001648.1|UniProtKB=W5M0L7 W5M0L7 PTHR11709:SF226 MULTI-COPPER OXIDASE CERULOPLASMIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005478.1|UniProtKB=W5ME17 W5ME17 PTHR31386:SF2 UNCHARACTERIZED PROTEIN KIAA2013 SIMILAR TO RIKEN CDNA 2510039O18 LEPOC|Ensembl=ENSLOCG00000003638.1|UniProtKB=W5M7H5 W5M7H5 PTHR24351:SF58 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;CCKR signaling map#P06959>RSK1/2#P07153;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000015318.1|UniProtKB=W5NDZ0 W5NDZ0 PTHR12570:SF10 FAMILY NOT NAMED NIPA MAGNESIUM TRANSPORTER 2 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011614.1|UniProtKB=W5N0W7 W5N0W7 PTHR31606:SF4 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009053.1|UniProtKB=W5MRS1 W5MRS1 MYH11 PTHR45615:SF23 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-11 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000010483.1|UniProtKB=W5MWU6 W5MWU6 PTHR11073:SF7 CALRETICULIN AND CALNEXIN CALMEGIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;ERAD pathway#GO:0036503;cellular biosynthetic process#GO:0044249;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012200.1|UniProtKB=W5N306 W5N306 PTHR12591:SF3 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE CATALYTIC SUBUNIT 1 hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 LEPOC|Ensembl=ENSLOCG00000000987.1|UniProtKB=W5LYA5 W5LYA5 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;external encapsulating structure organization#GO:0045229;regulation of molecular function#GO:0065009;supramolecular fiber organization#GO:0097435;regulation of hydrolase activity#GO:0051336;regulation of proteolysis#GO:0030162;collagen fibril organization#GO:0030199;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000001237.1|UniProtKB=W5LZ45 W5LZ45 PTHR31212:SF4 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000011069.1|UniProtKB=W5MYZ4 W5MYZ4 PTHR22640:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000014127.1|UniProtKB=W5N9V5 W5N9V5 PTHR13484:SF9 FIP1-LIKE 1 PROTEIN PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006388.1|UniProtKB=W5MH58 W5MH58 PTHR10177:SF70 CYCLINS G1_S-SPECIFIC CYCLIN-E2 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489 LEPOC|Ensembl=ENSLOCG00000008679.1|UniProtKB=W5MQA8 W5MQA8 BCL11B PTHR45993:SF4 B-CELL LYMPHOMA/LEUKEMIA 11 B-CELL LYMPHOMA_LEUKEMIA 11B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003323.1|UniProtKB=W5M6C0 W5M6C0 PTHR39313:SF1 IM:7138239 IM:7138239 LEPOC|Ensembl=ENSLOCG00000010821.1|UniProtKB=W5MY03 W5MY03 PTHR12791:SF28 GOLGI SNARE BET1-RELATED BET1 HOMOLOG SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000014596.1|UniProtKB=W5NBF3 W5NBF3 PTHR11409:SF42 ADENOSINE DEAMINASE ADENOSINE DEAMINASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;purine nucleoside catabolic process#GO:0006152;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;adenosine metabolic process#GO:0046085;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 LEPOC|Ensembl=ENSLOCG00000002207.1|UniProtKB=W5M2H2 W5M2H2 PTHR18949:SF1 CALDESMON LYMPHOCYTE-SPECIFIC PROTEIN 1 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000001890.1|UniProtKB=W5M1D5 W5M1D5 PTHR24336:SF12 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016006.1|UniProtKB=W5NGF1 W5NGF1 APLF PTHR21315:SF2 APRATAXIN AND PNK-LIKE FACTOR-RELATED APRATAXIN AND PNK-LIKE FACTOR catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011285.1|UniProtKB=W5MZR3 W5MZR3 PTHR18919:SF107 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000011387.1|UniProtKB=W5N041 W5N041 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005366.1|UniProtKB=W5MDL4 W5MDL4 PTHR12560:SF8 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 5 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016221.1|UniProtKB=W5NH94 W5NH94 PTHR23115:SF188 TRANSLATION FACTOR HBS1-LIKE PROTEIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010797.1|UniProtKB=W5MXZ0 W5MXZ0 PTHR11647:SF57 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;actin filament-based process#GO:0030029;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;actin cytoskeleton organization#GO:0030036;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 LEPOC|Ensembl=ENSLOCG00000014845.1|UniProtKB=W5NCC0 W5NCC0 PTHR45691:SF7 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008255.1|UniProtKB=W5MNQ7 W5MNQ7 PTHR12308:SF40 ANOCTAMIN ANOCTAMIN-10 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001952.1|UniProtKB=W5M1K8 W5M1K8 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;autophagy of mitochondrion#GO:0000422;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;regulation of mitochondrion organization#GO:0010821;catabolic process#GO:0009056;phosphorylation#GO:0016310;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;organelle disassembly#GO:1903008;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;autophagy#GO:0006914 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004069.1|UniProtKB=W5M903 W5M903 PTHR19957:SF88 SYNTAXIN SYNTAXIN-12 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;vacuole organization#GO:0007033;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;organelle fusion#GO:0048284;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;autophagosome assembly#GO:0000045;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 SNARE protein#PC00034;membrane traffic protein#PC00150 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Parkinson disease#P00049>Syntaxin#P01215;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000009614.1|UniProtKB=W5MTN2 W5MTN2 PCGF3 PTHR45893:SF3 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004156.1|UniProtKB=W5M9B5 W5M9B5 PTHR11388:SF142 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002843.1|UniProtKB=W5M4N8 W5M4N8 PTHR43884:SF12 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001069.1|UniProtKB=W5LYK0 W5LYK0 PTHR14978:SF0 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002779.1|UniProtKB=W5M4G8 W5M4G8 PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000016355.1|UniProtKB=W5NHT6 W5NHT6 PTHR45820:SF1 FI23527P1 PROTON-COUPLED ZINC ANTIPORTER SLC30A1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;response to stimulus#GO:0050896;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;response to toxic substance#GO:0009636;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001487.1|UniProtKB=W5LZY7 W5LZY7 PTHR23036:SF194 CYTOKINE RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000681.1|UniProtKB=W5LX96 W5LX96 PTHR46790:SF1 CENTROMERE PROTEIN N CENTROMERE PROTEIN N membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009717.1|UniProtKB=W5MU08 W5MU08 PTHR24246:SF52 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001611.1|UniProtKB=W5M0E4 W5M0E4 PTHR23339:SF65 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017175.1|UniProtKB=W5NKR8 W5NKR8 PTHR24115:SF194 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF6 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017273.1|UniProtKB=W5NL56 W5NL56 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014096.1|UniProtKB=W5N9Q7 W5N9Q7 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008394.1|UniProtKB=W5MP90 W5MP90 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004697.1|UniProtKB=W5MB69 W5MB69 PTHR14843:SF2 DEUBIQUITINATING PROTEIN VCIP135 DEUBIQUITINATING PROTEIN VCPIP1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;Golgi organization#GO:0007030;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;membrane organization#GO:0061024;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003608.1|UniProtKB=W5M7C0 W5M7C0 PTHR23316:SF7 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-3 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009015.1|UniProtKB=W5MRH9 W5MRH9 PTHR23073:SF24 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000017709.1|UniProtKB=W5NMF5 W5NMF5 PTHR24247:SF209 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M5 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000001904.1|UniProtKB=W5M1E3 W5M1E3 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005816.1|UniProtKB=W5MF66 W5MF66 PTHR23248:SF40 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007812.1|UniProtKB=W5MM75 W5MM75 PTHR11711:SF422 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000008269.1|UniProtKB=W5MNT2 W5MNT2 PTHR14787:SF1 C10ORF188 FAMILY MEMBER ATPASE PAAT LEPOC|Ensembl=ENSLOCG00000003802.1|UniProtKB=W5M828 W5M828 PTHR21538:SF26 ANILLIN/RHOTEKIN RTKN ANILLIN ISOFORM X1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring assembly#GO:0000915;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 actomyosin contractile ring#GO:0005826;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell division site#GO:0032153;contractile ring#GO:0070938;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000010930.1|UniProtKB=W5MYG6 W5MYG6 PTHR45929:SF2 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008835.1|UniProtKB=W5MQX3 W5MQX3 PTHR15036:SF57 PIKACHURIN-LIKE PROTEIN NEUREXIN-3 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001730.1|UniProtKB=W5M0T9 W5M0T9 FGF9 PTHR11486:SF28 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 9 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000015204.1|UniProtKB=W5NDK1 W5NDK1 GAS2L3 PTHR46756:SF7 TRANSGELIN GAS2-LIKE PROTEIN 3 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015172.1|UniProtKB=W5NDG0 W5NDG0 PTHR11473:SF24 AROMATIC AMINO ACID HYDROXYLASE PHENYLALANINE-4-HYDROXYLASE oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007314.1|UniProtKB=W5MKE6 W5MKE6 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007809.1|UniProtKB=W5MM78 W5MM78 PTHR12893:SF1 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 2 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000819.1|UniProtKB=W5LXV3 W5LXV3 PTHR10082:SF28 INTEGRIN BETA SUBUNIT INTEGRIN BETA-1 extracellular matrix binding#GO:0050840;integrin binding#GO:0005178;binding#GO:0005488;cytokine binding#GO:0019955;collagen binding#GO:0005518;cell adhesion molecule binding#GO:0050839;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 CCKR signaling map#P06959>ITGB1#G07277;CCKR signaling map#P06959>ITGB1#P07113;Integrin signalling pathway#P00034>Integrin beta#P00931;CCKR signaling map#P06959>ITGB1#G06984;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 LEPOC|Ensembl=ENSLOCG00000001180.1|UniProtKB=W5LYX1 W5LYX1 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007276.1|UniProtKB=W5MK95 W5MK95 PTHR24327:SF29 HOMEOBOX PROTEIN HOMEOBOX PROTEIN VENTX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013744.1|UniProtKB=W5N8I6 W5N8I6 PTHR45716:SF3 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016298.1|UniProtKB=W5NHK5 W5NHK5 PTHR11361:SF148 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007519.1|UniProtKB=W5ML68 W5ML68 PTHR24012:SF466 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1-LIKE nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005501.1|UniProtKB=W5ME29 W5ME29 PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001444.1|UniProtKB=W5LZU2 W5LZU2 PTHR28642:SF1 MEIOSIS 1 ARREST PROTEIN MEIOSIS 1 ARREST PROTEIN male gamete generation#GO:0048232;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;chromosome segregation#GO:0007059;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;male meiotic nuclear division#GO:0007140;multicellular organismal reproductive process#GO:0048609 LEPOC|Ensembl=ENSLOCG00000000114.1|UniProtKB=W5LVH1 W5LVH1 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 LEPOC|Ensembl=ENSLOCG00000016617.1|UniProtKB=W5NIS7 W5NIS7 PTHR45628:SF10 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Nicotine pharmacodynamics pathway#P06587>CACNA#P06600;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 LEPOC|Ensembl=ENSLOCG00000016286.1|UniProtKB=W5NHJ1 W5NHJ1 PTHR21448:SF0 SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011634.1|UniProtKB=W5N0Y5 W5N0Y5 PTHR31214:SF2 PROTEIN FAM221A-RELATED PROTEIN FAM221A LEPOC|Ensembl=ENSLOCG00000012782.1|UniProtKB=W5N522 W5N522 PTHR23037:SF27 CYTOKINE RECEPTOR INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;cytokine-mediated signaling pathway#GO:0019221;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004046.1|UniProtKB=W5M8X2 W5M8X2 PTHR24409:SF413 ZINC FINGER PROTEIN 142 DATILOGRAFO, ISOFORM A-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004378.1|UniProtKB=W5MA28 W5MA28 PTHR46485:SF7 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;positive regulation of actin filament bundle assembly#GO:0032233;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;actin cytoskeleton organization#GO:0030036;regulation of actin filament bundle assembly#GO:0032231;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Cytoskeletal regulation by Rho GTPase#P00016>LIMK#P00524 LEPOC|Ensembl=ENSLOCG00000004475.1|UniProtKB=W5MAF4 W5MAF4 PTHR10742:SF386 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011378.1|UniProtKB=W5N024 W5N024 PTHR35670:SF1 TRANSMEMBRANE PROTEIN 81 TRANSMEMBRANE PROTEIN 81 LEPOC|Ensembl=ENSLOCG00000002696.1|UniProtKB=W5M459 W5M459 PTHR45632:SF14 LD33804P KELCH-LIKE PROTEIN 33 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010879.1|UniProtKB=W5MY75 W5MY75 PTHR22950:SF244 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID TRANSPORTER 9 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009315.1|UniProtKB=W5MSK5 W5MSK5 PTHR12210:SF139 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005615.1|UniProtKB=W5MEG8 W5MEG8 PTHR46605:SF1 TUMOR NECROSIS FACTOR RECEPTOR DEATH DOMAIN-CONTAINING MEMBRANE PROTEIN NRADD growth factor binding#GO:0019838;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006395.1|UniProtKB=W5MH61 W5MH61 PTHR31428:SF5 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013534.1|UniProtKB=W5N7T2 W5N7T2 PTHR47958:SF90 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX5-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000012070.1|UniProtKB=W5N2J0 W5N2J0 PTHR10740:SF3 TRANSFORMING GROWTH FACTOR ALPHA PROBETACELLULIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of mitotic nuclear division#GO:0007088;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of organelle organization#GO:0010638;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of mitotic cell cycle#GO:0007346;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000002446.1|UniProtKB=W5M3B5 W5M3B5 PTHR42687:SF5 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL-LIKE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;aspartate family amino acid metabolic process#GO:0009066;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004144.1|UniProtKB=W5M9A2 W5M9A2 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011687.1|UniProtKB=W5N157 W5N157 PTHR14381:SF1 DACTYLIN F-BOX_WD REPEAT-CONTAINING PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000013234.1|UniProtKB=W5N6P0 W5N6P0 PTHR22802:SF402 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER E membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013992.1|UniProtKB=W5N9E0 W5N9E0 PTHR45636:SF13 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011404.1|UniProtKB=W5N060 W5N060 PTHR23419:SF1 DIVALENT CATION TOLERANCE CUTA-RELATED PROTEIN CUTA copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017831.1|UniProtKB=W5NMS5 W5NMS5 PTHR11214:SF20 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 1 UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001102.1|UniProtKB=W5LYP6 W5LYP6 PTHR24185:SF1 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003739.1|UniProtKB=W5M7U6 W5M7U6 PTHR12865:SF7 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;Golgi organization#GO:0007030;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;glycerolipid metabolic process#GO:0046486;organelle organization#GO:0006996;glycerophospholipid biosynthetic process#GO:0046474;vesicle organization#GO:0016050;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000018106.1|UniProtKB=W5NNJ8 W5NNJ8 PTHR17070:SF0 DEXAMETHASONE-INDUCED PROTEIN DEXAMETHASONE-INDUCED PROTEIN LEPOC|Ensembl=ENSLOCG00000011465.1|UniProtKB=W5N0D8 W5N0D8 PTHR11455:SF63 CRYPTOCHROME PHOTOLYASE_CRYPTOCHROME ALPHA_BETA DOMAIN-CONTAINING PROTEIN nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;deoxyribodipyrimidine photo-lyase activity#GO:0003904;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA photolyase#PC00014 LEPOC|Ensembl=ENSLOCG00000008502.1|UniProtKB=W5MPN6 W5MPN6 PTHR11418:SF0 GLUCAGON PRO-GLUCAGON CCKR signaling map#P06959>GCG#G07291;CCKR signaling map#P06959>GCG#G06997 LEPOC|Ensembl=ENSLOCG00000014950.1|UniProtKB=W5NCQ0 W5NCQ0 PTHR21208:SF0 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;glucose metabolic process#GO:0006006;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007590.1|UniProtKB=W5MLF0 W5MLF0 PTHR23310:SF54 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000016137.1|UniProtKB=W5NGX4 W5NGX4 PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015559.1|UniProtKB=W5NEU3 W5NEU3 PTHR31423:SF3 YBAK DOMAIN-CONTAINING PROTEIN PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED LEPOC|Ensembl=ENSLOCG00000005376.1|UniProtKB=W5MDM0 W5MDM0 ZNHIT6 PTHR13483:SF3 BOX C_D SNORNA PROTEIN 1-RELATED BOX C_D SNORNA PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of LSU-rRNA#GO:0000470 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001224.1|UniProtKB=W5LZ31 W5LZ31 PTHR46799:SF1 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010054.1|UniProtKB=W5MV87 W5MV87 RASGEF1C PTHR23113:SF186 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1C nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011639.1|UniProtKB=W5N0Z2 W5N0Z2 PTHR43684:SF5 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014027.1|UniProtKB=W5N9I7 W5N9I7 PTHR12372:SF2 PECANEX PECANEX-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016545.1|UniProtKB=W5NIH3 W5NIH3 PTHR24366:SF65 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000014503.1|UniProtKB=W5NB44 W5NB44 PTHR13027:SF13 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG B endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000015049.1|UniProtKB=W5ND15 W5ND15 PTHR46283:SF3 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012560.1|UniProtKB=W5N4A7 W5N4A7 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000004868.1|UniProtKB=W5MBU9 W5MBU9 PTHR14881:SF4 LISH DOMAIN-CONTAINING PROTEIN ARMC9 LISH DOMAIN-CONTAINING PROTEIN ARMC9 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005130.1|UniProtKB=W5MCR6 W5MCR6 PTHR24414:SF63 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 46 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000018020.1|UniProtKB=W5NNB2 W5NNB2 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006635.1|UniProtKB=W5MI02 W5MI02 PTHR31539:SF1 CENTROSOMAL PROTEIN OF 19K CEP19 CENTROSOMAL PROTEIN OF 19 KDA vesicle targeting, to, from or within Golgi#GO:0048199;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;organelle localization#GO:0051640;cell projection organization#GO:0030030;vesicle localization#GO:0051648;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;establishment of organelle localization#GO:0051656 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000015016.1|UniProtKB=W5NCX8 W5NCX8 PTHR12232:SF5 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN ADAPTER SH3BGRL cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015434.1|UniProtKB=W5NED9 W5NED9 PTHR12372:SF5 PECANEX PECANEX-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004714.1|UniProtKB=W5MBA3 W5MBA3 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of natural killer cell mediated immunity#GO:0002715;cell recognition#GO:0008037;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;regulation of immune response#GO:0050776;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;regulation of response to stress#GO:0080134;detection of stimulus#GO:0051606;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;regulation of cell killing#GO:0031341;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009239.1|UniProtKB=W5MSB6 W5MSB6 PTHR11453:SF15 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006346.1|UniProtKB=W5MH01 W5MH01 PTHR10224:SF16 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013076.1|UniProtKB=W5N658 W5N658 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003549.1|UniProtKB=W5M765 W5M765 PTHR23253:SF23 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012549.1|UniProtKB=W5N494 W5N494 PTHR15941:SF9 MYOZENIN MYOZENIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 supramolecular complex#GO:0099080;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008659.1|UniProtKB=W5MQ74 W5MQ74 PTHR12141:SF3 ARFAPTIN-RELATED ARFAPTIN-2 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of actin filament-based process#GO:0032970 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 Huntington disease#P00029>Arfaptin-2#P00793 LEPOC|Ensembl=ENSLOCG00000006115.1|UniProtKB=W5MG82 W5MG82 PTHR43191:SF2 RRNA METHYLTRANSFERASE 3, RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000011304.1|UniProtKB=W5MZT7 W5MZT7 PTHR18829:SF0 PROTEIN YAE1 HOMOLOG PROTEIN YAE1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000003306.1|UniProtKB=W5M6B1 W5M6B1 PTHR11430:SF121 LIPOCALIN COMPLEMENT C8 GAMMA CHAIN transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008222.1|UniProtKB=W5MNP0 W5MNP0 PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010714.1|UniProtKB=W5MXM1 W5MXM1 PTHR13617:SF14 PROTEIN ABHD18 PROTEIN ABHD18 LEPOC|Ensembl=ENSLOCG00000011802.1|UniProtKB=W5N1K3 W5N1K3 PTHR19432:SF37 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;carbohydrate transmembrane transporter activity#GO:0015144;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009143.1|UniProtKB=W5MRY7 W5MRY7 PTHR45961:SF7 IP21249P DUAL SPECIFICITY PHOSPHATASE 28 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000001939.1|UniProtKB=W5M1J3 W5M1J3 PTHR10802:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40B protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017996.1|UniProtKB=W5NN88 W5NN88 PTHR12871:SF3 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009710.1|UniProtKB=W5MU07 W5MU07 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 LEPOC|Ensembl=ENSLOCG00000003064.1|UniProtKB=W5M5E8 W5M5E8 PTHR42919:SF8 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000002050.1|UniProtKB=W5M1X0 W5M1X0 PTHR31435:SF9 PROTEIN NATD1 PROTEIN NATD1 LEPOC|Ensembl=ENSLOCG00000009609.1|UniProtKB=W5MTP0 W5MTP0 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;regulation of receptor signaling pathway via STAT#GO:1904892;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011702.1|UniProtKB=W5N178 W5N178 PTHR46451:SF1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001552.1|UniProtKB=W5M0B2 W5M0B2 PTHR22829:SF6 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 1 PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of hydrolase activity#GO:0051336;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 LEPOC|Ensembl=ENSLOCG00000001805.1|UniProtKB=W5M128 W5M128 FNDC11 PTHR14537:SF0 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000006744.1|UniProtKB=W5MID8 W5MID8 UBE2U PTHR24067:SF252 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 U ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;protein-DNA complex#GO:0032993;chromosome#GO:0005694;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002142.1|UniProtKB=W5M281 W5M281 PTHR11534:SF3 MYOGENIC FACTOR MYOGENIC FACTOR 5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 muscle organ development#GO:0007517;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012312.1|UniProtKB=W5N3D8 W5N3D8 PTHR12626:SF3 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010667.1|UniProtKB=W5MXG0 W5MXG0 PTHR10177:SF57 CYCLINS CYCLIN-I2 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000000303.1|UniProtKB=W5LW23 W5LW23 PTHR18884:SF128 SEPTIN SI:CH211-282J17.12-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000005121.1|UniProtKB=W5MCR4 W5MCR4 PTHR44549:SF1 ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000234.1|UniProtKB=W5LVV1 W5LVV1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013295.1|UniProtKB=W5N6X8 W5N6X8 PTHR21646:SF20 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 43 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003379.1|UniProtKB=W5M6I8 W5M6I8 PTHR20914:SF26 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 PHOSPHOLIPASE A2 INHIBITOR CNF-LIKE scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004783.1|UniProtKB=W5MBH8 W5MBH8 PTHR10822:SF12 GLYPICAN GLYPICAN-5 regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of protein localization to membrane#GO:1905475;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;regulation of cellular localization#GO:0060341;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002596.1|UniProtKB=W5M3U2 W5M3U2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016394.1|UniProtKB=W5NHY7 W5NHY7 PTHR10159:SF299 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 10 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of protein serine/threonine kinase activity#GO:0071900;protein metabolic process#GO:0019538;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131;p38 MAPK pathway#P05918>MKP5#P05921 LEPOC|Ensembl=ENSLOCG00000007874.1|UniProtKB=W5MMF2 W5MMF2 PTHR45716:SF6 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000005907.1|UniProtKB=W5MFH8 W5MFH8 PTHR46299:SF2 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2 LEPOC|Ensembl=ENSLOCG00000001479.1|UniProtKB=W5LZZ4 W5LZZ4 PTHR21222:SF1 MIT DOMAIN-CONTAINING PROTEIN 1 MIT DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005091.1|UniProtKB=W5MCM3 W5MCM3 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013583.1|UniProtKB=W5N7Z3 W5N7Z3 PTHR43829:SF29 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;amide transmembrane transporter activity#GO:0042887;channel activity#GO:0015267;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;water transport#GO:0006833;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;fluid transport#GO:0042044 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003864.1|UniProtKB=W5M8G9 W5M8G9 PTHR45636:SF26 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015400.1|UniProtKB=W5NE89 W5NE89 PTHR11388:SF133 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017739.1|UniProtKB=W5NMI4 W5NMI4 PTHR31416:SF1 TRANSMEMBRANE PROTEIN 125 TRANSMEMBRANE PROTEIN 125 LEPOC|Ensembl=ENSLOCG00000011792.1|UniProtKB=W5N1I6 W5N1I6 PTHR10825:SF74 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER 6 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007009.1|UniProtKB=W5MJC8 W5MJC8 PTHR23429:SF7 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GDH_6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;hexose metabolic process#GO:0019318;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013219.1|UniProtKB=W5N6M3 W5N6M3 PTHR21472:SF20 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000013704.1|UniProtKB=W5N8E3 W5N8E3 PTHR14374:SF0 FOIE GRAS TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 LEPOC|Ensembl=ENSLOCG00000004984.1|UniProtKB=W5MC97 W5MC97 CLDN10 PTHR12002:SF13 CLAUDIN CLAUDIN-10 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000004283.1|UniProtKB=W5M9R8 W5M9R8 PTHR22775:SF31 SORTING NEXIN SORTING NEXIN-19 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016811.1|UniProtKB=W5NJG7 W5NJG7 PTHR14154:SF3 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transmembrane transport#GO:1903825;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transmembrane transport#GO:1905039 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015750.1|UniProtKB=W5NFI3 W5NFI3 PTHR32005:SF4 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178A inorganic ion homeostasis#GO:0098771;regulation of myeloid cell differentiation#GO:0045637;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;regulation of multicellular organismal development#GO:2000026;cellular homeostasis#GO:0019725;regulation of cell differentiation#GO:0045595;chemical homeostasis#GO:0048878;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of hemopoiesis#GO:1903706;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;negative regulation of immune system process#GO:0002683;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002501.1|UniProtKB=W5M3I0 W5M3I0 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004033.1|UniProtKB=W5M8W1 W5M8W1 PTHR23037:SF42 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT GAMMA ISOFORM X1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immunoglobulin mediated immune response#GO:0016064;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;leukocyte mediated immunity#GO:0002443;cell communication#GO:0007154;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015896.1|UniProtKB=W5NG15 W5NG15 PTHR15140:SF31 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE E chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005656.1|UniProtKB=W5MEM0 W5MEM0 MPHOSPH9 PTHR14926:SF1 M-PHASE PHOSPHOPROTEIN 9 M-PHASE PHOSPHOPROTEIN 9 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007164.1|UniProtKB=W5MJW4 W5MJW4 PTHR24060:SF30 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061;Metabotropic glutamate receptor group III pathway#P00039>mGluR 5#P01037;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Endogenous cannabinoid signaling#P05730>mGluR#P05748 LEPOC|Ensembl=ENSLOCG00000017124.1|UniProtKB=W5NKK1 W5NKK1 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013621.1|UniProtKB=W5N836 W5N836 PTHR48051:SF14 FAMILY NOT NAMED LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 ISOFORM X1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002637.1|UniProtKB=W5M401 W5M401 PTHR11039:SF37 NEBULIN NEBULIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;I band#GO:0031674 LEPOC|Ensembl=ENSLOCG00000015994.1|UniProtKB=W5NGE1 W5NGE1 PTHR14618:SF4 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 ISOFORM X1-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011755.1|UniProtKB=W5N1E2 W5N1E2 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000018182.1|UniProtKB=W5NNS4 W5NNS4 PTHR15258:SF1 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 2 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 LEPOC|Ensembl=ENSLOCG00000009602.1|UniProtKB=W5MTM3 W5MTM3 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG cell division#GO:0051301;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of mitotic nuclear division#GO:0045840;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013666.1|UniProtKB=W5N891 W5N891 PTHR24416:SF296 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011023.1|UniProtKB=W5MYS1 W5MYS1 PTHR11267:SF98 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000006420.1|UniProtKB=W5MH96 W5MH96 PTHR23067:SF8 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006984.1|UniProtKB=W5MJ90 W5MJ90 PTHR24286:SF100 CYTOCHROME P450 26 CYTOCHROME P450 26C1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012361.1|UniProtKB=W5N3K8 W5N3K8 PTHR10811:SF1 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE RADICAL FRINGE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of Notch signaling pathway#GO:0008593 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 LEPOC|Ensembl=ENSLOCG00000002455.1|UniProtKB=W5M3C7 W5M3C7 PTHR10072:SF41 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015773.1|UniProtKB=W5NFK8 W5NFK8 PTHR10155:SF7 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 LEPOC|Ensembl=ENSLOCG00000005429.1|UniProtKB=W5MDT6 W5MDT6 PTHR16515:SF20 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 12 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012226.1|UniProtKB=W5N332 W5N332 PTHR19964:SF16 MULTIPLE PDZ DOMAIN PROTEIN SYNTAXIN-BINDING PROTEIN 4 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;regulation of peptide secretion#GO:0002791;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;response to peptide#GO:1901652;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;cellular response to insulin stimulus#GO:0032869;regulation of protein transport#GO:0051223;signaling#GO:0023052;regulation of protein localization#GO:0032880;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of peptide hormone secretion#GO:0090276;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular localization#GO:0060341;regulation of hormone levels#GO:0010817;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010597.1|UniProtKB=W5MX70 W5MX70 PTHR23137:SF1 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2B LEPOC|Ensembl=ENSLOCG00000009209.1|UniProtKB=W5MS73 W5MS73 PTHR24388:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 367 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002433.1|UniProtKB=W5M395 W5M395 EIF3I PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000002478.1|UniProtKB=W5M3F8 W5M3F8 PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;DNA-templated transcription#GO:0006351;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 histone acetyltransferase complex#GO:0000123;DNA-directed RNA polymerase complex#GO:0000428;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;SAGA complex#GO:0000124;membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007060.1|UniProtKB=W5MJI9 W5MJI9 PTHR23063:SF21 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 2 transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000008447.1|UniProtKB=W5MPG7 W5MPG7 PTHR11537:SF90 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004929.1|UniProtKB=W5MC28 W5MC28 PTHR10881:SF46 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000902.1|UniProtKB=W5LY20 W5LY20 PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007339.1|UniProtKB=W5MKI2 W5MKI2 PTHR11266:SF39 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;non-membrane-bounded organelle assembly#GO:0140694 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014915.1|UniProtKB=W5NCK7 W5NCK7 PTHR45767:SF3 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PI3 kinase pathway#P00048>FOXO#P01198 LEPOC|Ensembl=ENSLOCG00000011249.1|UniProtKB=W5MZL3 W5MZL3 PTHR12800:SF2 CDC37-RELATED HSP90 CO-CHAPERONE CDC37-LIKE 1 protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein stabilization#GO:0050821;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;biological regulation#GO:0065007;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002963.1|UniProtKB=W5M537 W5M537 PTHR10048:SF28 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 LEPOC|Ensembl=ENSLOCG00000011035.1|UniProtKB=W5MYT3 W5MYT3 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000010742.1|UniProtKB=W5MXQ8 W5MXQ8 PTHR25465:SF12 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25 ISOFORM X1 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015721.1|UniProtKB=W5NFE1 W5NFE1 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 LEPOC|Ensembl=ENSLOCG00000015934.1|UniProtKB=W5NG58 W5NG58 BMT2 PTHR21008:SF0 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000001052.1|UniProtKB=W5LYK6 W5LYK6 PTHR45828:SF3 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC-CHELATE REDUCTASE 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006576.1|UniProtKB=W5MHT5 W5MHT5 PTHR45677:SF8 GLUTAMATE DECARBOXYLASE-RELATED CYSTEINE SULFINIC ACID DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000011270.1|UniProtKB=W5MZP7 W5MZP7 PTHR45851:SF1 MYC PROTO-ONCOGENE MYC PROTO-ONCOGENE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>MYC#G07272;p53 pathway feedback loops 2#P04398>Myc#P04649;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Interleukin signaling pathway#P00036>c-Myc#P00995;Oxidative stress response#P00046>Myc#P01124;CCKR signaling map#P06959>MYC#G06979;PDGF signaling pathway#P00047>c-Myc#P01172 LEPOC|Ensembl=ENSLOCG00000012043.1|UniProtKB=W5N2F5 W5N2F5 PTHR13680:SF33 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000005277.1|UniProtKB=W5MD98 W5MD98 PTHR31626:SF2 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171B LEPOC|Ensembl=ENSLOCG00000017424.1|UniProtKB=W5NLM0 W5NLM0 PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012438.1|UniProtKB=W5N3V1 W5N3V1 PTHR23147:SF237 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014815.1|UniProtKB=W5NC84 W5NC84 RPS27L PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008507.1|UniProtKB=W5MPP1 W5MPP1 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003479.1|UniProtKB=W5M719 W5M719 PTHR11733:SF130 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 LEPOC|Ensembl=ENSLOCG00000016642.1|UniProtKB=W5NIV0 W5NIV0 PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008876.1|UniProtKB=W5MR02 W5MR02 PTHR23063:SF57 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000015678.1|UniProtKB=W5NF89 W5NF89 AARS PTHR11777:SF8 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016845.1|UniProtKB=W5NJL3 W5NJL3 PTHR12656:SF11 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000013178.1|UniProtKB=W5N6I2 W5N6I2 PTHR31061:SF37 LD22376P HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000012274.1|UniProtKB=W5N395 W5N395 PTHR24073:SF471 DRAB5-RELATED RAS-RELATED PROTEIN RAB-24 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001342.1|UniProtKB=W5LZJ4 W5LZJ4 PTHR13335:SF1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;TORC2 signaling#GO:0038203;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013271.1|UniProtKB=W5N6U9 W5N6U9 PTHR10649:SF3 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009169.1|UniProtKB=W5MS24 W5MS24 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural constituent of cytoskeleton#GO:0005200;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 LEPOC|Ensembl=ENSLOCG00000016834.1|UniProtKB=W5NJJ7 W5NJJ7 PTHR31576:SF2 TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;RNA polymerase I transcription regulatory region sequence-specific DNA binding#GO:0001163 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;rRNA transcription#GO:0009303;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 General transcription by RNA polymerase I#P00022>TAF-IB#P00650 LEPOC|Ensembl=ENSLOCG00000005696.1|UniProtKB=W5MER7 W5MER7 MAML2 PTHR15692:SF9 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 2 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;Notch signaling pathway#GO:0007219;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011555.1|UniProtKB=W5N0U1 W5N0U1 PTHR45628:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 LEPOC|Ensembl=ENSLOCG00000012273.1|UniProtKB=W5N391 W5N391 PTHR10885:SF0 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005798.1|UniProtKB=W5MF44 W5MF44 PTHR11960:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009080.1|UniProtKB=W5MRR1 W5MRR1 PTHR11388:SF86 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009962.1|UniProtKB=W5MUX4 W5MUX4 PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;monosaccharide metabolic process#GO:0005996;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849 LEPOC|Ensembl=ENSLOCG00000008069.1|UniProtKB=W5MN45 W5MN45 PTHR12496:SF2 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25B RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000013106.1|UniProtKB=W5N683 W5N683 PTHR11085:SF10 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 LEPOC|Ensembl=ENSLOCG00000014286.1|UniProtKB=W5NAD3 W5NAD3 PTHR15435:SF2 KICSTOR COMPLEX PROTEIN KAPTIN KICSTOR COMPLEX PROTEIN KAPTIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;negative regulation of TORC1 signaling#GO:1904262 cell leading edge#GO:0031252;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027 LEPOC|Ensembl=ENSLOCG00000012054.1|UniProtKB=W5N2H5 W5N2H5 PTHR24068:SF532 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2D N-TERMINAL LIKE 1-RELATED ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000011583.1|UniProtKB=W5N0S2 W5N0S2 PTHR11861:SF11 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE GLYCOPROTEIN NMB cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000014585.1|UniProtKB=W5NBE2 W5NBE2 PTHR12701:SF15 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 31 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004394.1|UniProtKB=W5MA56 W5MA56 PTHR12802:SF9 SWI/SNF COMPLEX-RELATED SWI_SNF COMPLEX SUBUNIT SMARCC1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000010328.1|UniProtKB=W5MW96 W5MW96 ATP6V0D2 PTHR11028:SF0 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 regulation of intracellular pH#GO:0051453;cellular localization#GO:0051641;vacuolar transport#GO:0007034;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010437.1|UniProtKB=W5MWN1 W5MWN1 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER X2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014997.1|UniProtKB=W5NCV9 W5NCV9 PTHR11909:SF156 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;import into cell#GO:0098657 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000002883.1|UniProtKB=W5M4V6 W5M4V6 PTHR24020:SF39 COLLAGEN ALPHA COLLAGEN ALPHA-1(XX) CHAIN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011351.1|UniProtKB=W5MZZ2 W5MZZ2 PTHR16124:SF3 MIS18-BINDING PROTEIN 1 MIS18-BINDING PROTEIN 1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014489.1|UniProtKB=W5NB24 W5NB24 PTHR10807:SF40 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 1 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000011549.1|UniProtKB=W5N0N3 W5N0N3 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 LEPOC|Ensembl=ENSLOCG00000017512.1|UniProtKB=W5NLV8 W5NLV8 PTHR28649:SF3 PROTEIN REPRIMO-RELATED REPRIMO-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000014702.1|UniProtKB=W5NBU7 W5NBU7 PTHR11089:SF33 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3-LIKE PROTEIN intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010401.1|UniProtKB=W5MWJ1 W5MWJ1 PTHR28651:SF1 TRANSMEMBRANE PROTEIN 232 TRANSMEMBRANE PROTEIN 232 LEPOC|Ensembl=ENSLOCG00000017419.1|UniProtKB=W5NLL5 W5NLL5 PTHR23428:SF344 HISTONE H2B HISTONE H2B TYPE 2-K1 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009472.1|UniProtKB=W5MT57 W5MT57 PTHR15335:SF7 PROTEIN TFG PROTEIN TFG localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015949.1|UniProtKB=W5NG82 W5NG82 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001026.1|UniProtKB=W5LYE5 W5LYE5 PTHR46139:SF2 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005061.1|UniProtKB=W5MCI4 W5MCI4 PTHR28597:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;regulation of secretion by cell#GO:1903530;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;negative regulation of transport#GO:0051051;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;regulation of exocytosis#GO:0017157;negative regulation of molecular function#GO:0044092 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007137.1|UniProtKB=W5MJT2 W5MJT2 PTHR11561:SF18 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP] cation binding#GO:0043169;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 dicarboxylic acid metabolic process#GO:0043648;liver development#GO:0001889;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;response to extracellular stimulus#GO:0009991;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;neutral lipid metabolic process#GO:0006638;cellular response to hormone stimulus#GO:0032870;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;alcohol metabolic process#GO:0006066;intracellular chemical homeostasis#GO:0055082;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;hexose biosynthetic process#GO:0019319;organic acid catabolic process#GO:0016054;response to glucose#GO:0009749;small molecule catabolic process#GO:0044282;response to stress#GO:0006950;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;small molecule biosynthetic process#GO:0044283;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;monosaccharide metabolic process#GO:0005996;lipid metabolic process#GO:0006629;response to organic cyclic compound#GO:0014070;response to insulin#GO:0032868;epithelium development#GO:0060429;response to peptide hormone#GO:0043434;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;developmental process#GO:0032502;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;cellular response to nitrogen compound#GO:1901699;cellular response to lipid#GO:0071396;system development#GO:0048731;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;cellular response to organic cyclic compound#GO:0071407;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;carbohydrate biosynthetic process#GO:0016051;cellular response to stimulus#GO:0051716;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;glycerolipid biosynthetic process#GO:0045017;multicellular organism development#GO:0007275;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;epithelial cell differentiation#GO:0030855;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;tissue development#GO:0009888;glucose metabolic process#GO:0006006;fatty acid catabolic process#GO:0009062;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;intracellular glucose homeostasis#GO:0001678;response to hormone#GO:0009725;response to chemical#GO:0042221;response to starvation#GO:0042594;hexose metabolic process#GO:0019318;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;response to steroid hormone#GO:0048545 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 LEPOC|Ensembl=ENSLOCG00000016019.1|UniProtKB=W5NGH4 W5NGH4 PTHR11923:SF12 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 PLATELET GLYCOPROTEIN 4 cargo receptor activity#GO:0038024 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008081.1|UniProtKB=W5MN57 W5MN57 PTHR10907:SF47 REGUCALCIN REGUCALCIN cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;heterocycle metabolic process#GO:0046483;carbohydrate biosynthetic process#GO:0016051;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000011680.1|UniProtKB=W5N146 W5N146 PTHR22950:SF188 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 1 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;glycine transmembrane transporter activity#GO:0015187;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;proton transmembrane transport#GO:1902600;organic acid transport#GO:0015849;alanine transport#GO:0032328;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;monoatomic cation transmembrane transport#GO:0098655 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011143.1|UniProtKB=W5MZ79 W5MZ79 PTHR11364:SF27 THIOSULFATE SULFERTANSFERASE SULFURTRANSFERASE thiosulfate sulfurtransferase activity#GO:0004792;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004991.1|UniProtKB=W5MCA8 W5MCA8 PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;organic substance transport#GO:0071702;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nuclear export#GO:0051168;rRNA metabolic process#GO:0016072;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018053.1|UniProtKB=W5NNE5 W5NNE5 PTHR12002:SF220 CLAUDIN CLAUDIN 8-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000017863.1|UniProtKB=W5NMV7 W5NMV7 PTHR11467:SF20 HISTONE H1 H15 DOMAIN-CONTAINING PROTEIN-RELATED nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;chromosome condensation#GO:0030261;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA recombination#GO:0000018;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016599.1|UniProtKB=W5NIP3 W5NIP3 PTHR22930:SF237 FAMILY NOT NAMED SI:CH73-257C13.2 LEPOC|Ensembl=ENSLOCG00000009372.1|UniProtKB=W5MSR7 W5MSR7 PTHR15143:SF0 TELETHONIN TELETHONIN structural constituent of muscle#GO:0008307;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;structural molecule activity#GO:0005198;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;detection of mechanical stimulus#GO:0050982;muscle organ development#GO:0007517;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;system process#GO:0003008;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;skeletal muscle contraction#GO:0003009;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;response to abiotic stimulus#GO:0009628;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;heart morphogenesis#GO:0003007;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle contraction#GO:0060048;cardiac muscle tissue development#GO:0048738;detection of stimulus#GO:0051606;cellular component organization#GO:0016043;nervous system process#GO:0050877;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to mechanical stimulus#GO:0009612;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;heart process#GO:0003015;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;sarcomere#GO:0030017;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;I band#GO:0031674;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001555.1|UniProtKB=W5M075 W5M075 PTHR47193:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 male gamete generation#GO:0048232;regulation of microtubule-based process#GO:0032886;regulation of locomotion#GO:0040012;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;cilium movement involved in cell motility#GO:0060294;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;spermatogenesis#GO:0007283;monoatomic cation transport#GO:0006812;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609;metal ion transport#GO:0030001;gamete generation#GO:0007276;regulation of cell motility#GO:2000145;multicellular organism reproduction#GO:0032504;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;CatSper complex#GO:0036128;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016884.1|UniProtKB=W5NJR2 W5NJR2 PTHR10063:SF2 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000014349.1|UniProtKB=W5NAL0 W5NAL0 PTHR13596:SF0 SMALL EDRK-RICH FACTOR 1 SI:CH211-39K3.2-RELATED LEPOC|Ensembl=ENSLOCG00000015392.1|UniProtKB=W5NE82 W5NE82 PTHR34343:SF1 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 establishment or maintenance of cell polarity#GO:0007163;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;tube development#GO:0035295;cell motility#GO:0048870;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;establishment of cell polarity#GO:0030010;system development#GO:0048731;microtubule-based process#GO:0007017;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;cell migration#GO:0016477 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000225.1|UniProtKB=W5LVU3 W5LVU3 PRADC1 PTHR22702:SF1 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007337.1|UniProtKB=W5MKH8 W5MKH8 PTHR14611:SF1 TECTONIC FAMILY MEMBER TECTONIC-1 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000009632.1|UniProtKB=W5MTR2 W5MTR2 PTHR11071:SF257 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NK-TUMOR RECOGNITION PROTEIN peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004274.1|UniProtKB=W5M9P9 W5M9P9 PTHR23288:SF3 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL MARVEL DOMAIN-CONTAINING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell junction assembly#GO:0034329;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;cell-cell junction organization#GO:0045216;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;cell-cell junction assembly#GO:0007043;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;tight junction#GO:0070160;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;apical junction complex#GO:0043296;plasma membrane#GO:0005886 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000014136.1|UniProtKB=W5N9W0 W5N9W0 PTHR10192:SF5 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN transferase activity#GO:0016740;catalytic activity#GO:0003824 heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004387.1|UniProtKB=W5MA33 W5MA33 PTHR18976:SF1 APOLIPOPROTEIN APOLIPOPROTEIN A-IV cholesterol transfer activity#GO:0120020;molecular function activator activity#GO:0140677;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;binding#GO:0005488;molecular function regulator activity#GO:0098772;sterol transporter activity#GO:0015248;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;phospholipid binding#GO:0005543;enzyme regulator activity#GO:0030234;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;cholesterol metabolic process#GO:0008203;homeostatic process#GO:0042592;alcohol metabolic process#GO:0006066;phospholipid transport#GO:0015914;chemical homeostasis#GO:0048878;lipid transport#GO:0006869;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;cholesterol transport#GO:0030301;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;cholesterol efflux#GO:0033344;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;high-density lipoprotein particle#GO:0034364;organelle#GO:0043226;vesicle#GO:0031982 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000000331.1|UniProtKB=W5LW49 W5LW49 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005249.1|UniProtKB=W5MD66 W5MD66 CDH8 PTHR24027:SF273 CADHERIN-23 CADHERIN-8 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;extracellular region#GO:0005576;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;adherens junction#GO:0005912;cell projection#GO:0042995;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000016836.1|UniProtKB=W5NJK2 W5NJK2 PTHR16263:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 38 TETRATRICOPEPTIDE REPEAT PROTEIN 38 LEPOC|Ensembl=ENSLOCG00000000730.1|UniProtKB=W5LXG4 W5LXG4 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015878.1|UniProtKB=W5NFZ6 W5NFZ6 PTHR15722:SF2 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000018345.1|UniProtKB=W5NP87 W5NP87 FAM237B PTHR36690:SF2 PROTEIN FAM237A PROTEIN FAM237A LEPOC|Ensembl=ENSLOCG00000005188.1|UniProtKB=W5MD28 W5MD28 PTHR13743:SF123 BEIGE/BEACH-RELATED PROTEIN FAN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000787.1|UniProtKB=W5LXL7 W5LXL7 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000002993.1|UniProtKB=W5M566 W5M566 PTHR16489:SF11 GH11727P PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;regulation of phosphoprotein phosphatase activity#GO:0043666;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;positive regulation of catalytic activity#GO:0043085;regulation of phosphatase activity#GO:0010921;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007572.1|UniProtKB=W5MLD0 W5MLD0 PTHR14942:SF0 U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN LEPOC|Ensembl=ENSLOCG00000000028.1|UniProtKB=W5LV75 W5LV75 PTHR24253:SF144 TRANSMEMBRANE PROTEASE SERINE CHYMOTRYPSIN-LIKE PROTEASE CTRL-1-RELATED serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008814.1|UniProtKB=W5MQT7 W5MQT7 PTHR45720:SF6 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 2 voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002775.1|UniProtKB=W5M4G0 W5M4G0 PTHR45744:SF2 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213 LEPOC|Ensembl=ENSLOCG00000010376.1|UniProtKB=W5MWF6 W5MWF6 PTHR21636:SF2 PROTEIN DOK-7 PROTEIN DOK-7 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;neuromuscular junction development#GO:0007528;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000016331.1|UniProtKB=W5NHQ4 W5NHQ4 PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002460.1|UniProtKB=W5M3I6 W5M3I6 PPP4R1 PTHR10648:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000014657.1|UniProtKB=W5NBN5 W5NBN5 PTHR47091:SF1 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 3 cellular developmental process#GO:0048869;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;circulatory system development#GO:0072359;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;developmental process#GO:0032502;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;muscle structure development#GO:0061061;muscle cell development#GO:0055001;cell development#GO:0048468;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;cell differentiation#GO:0030154;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007305.1|UniProtKB=W5MKD6 W5MKD6 PTHR34757:SF1 JUNCTIONAL PROTEIN ASSOCIATED WITH CORONARY ARTERY DISEASE JUNCTIONAL CADHERIN 5-ASSOCIATED PROTEIN regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell population proliferation#GO:0008284;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;leading edge membrane#GO:0031256;cell junction#GO:0030054;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell projection#GO:0042995;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002550.1|UniProtKB=W5M3Q3 W5M3Q3 DOK5 PTHR21258:SF45 DOCKING PROTEIN RELATED DOCKING PROTEIN 5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017256.1|UniProtKB=W5NL35 W5NL35 PTHR10383:SF15 SERINE INCORPORATOR SERINE INCORPORATOR 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006000.1|UniProtKB=W5MFU0 W5MFU0 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018299.1|UniProtKB=W5NP41 W5NP41 PTHR15284:SF4 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN E4 BINDING PROTEIN 4-2 circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000003162.1|UniProtKB=W5M5S8 W5M5S8 PTHR11850:SF59 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>TGIF1#P06725 LEPOC|Ensembl=ENSLOCG00000001119.1|UniProtKB=W5LYS0 W5LYS0 PTHR10048:SF107 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;p53 pathway feedback loops 2#P04398>P110ALPHA#G04707;PI3 kinase pathway#P00048>p110#P01192;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;p53 pathway#P00059>P110alpha#P04633;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway feedback loops 2#P04398>P110alpha#P04657;p53 pathway#P00059>p110alpha#G04694;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>P110alpha#P04498;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>p110alpha#G04676;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Interleukin signaling pathway#P00036>PI3K#P00990;PI3 kinase pathway#P00048>P110ACT#P01177 LEPOC|Ensembl=ENSLOCG00000013052.1|UniProtKB=W5N615 W5N615 PTHR24410:SF12 HL07962P-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 17 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008556.1|UniProtKB=W5MPV2 W5MPV2 PTHR11523:SF10 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011718.1|UniProtKB=W5N197 W5N197 PTHR12924:SF2 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008984.1|UniProtKB=W5MRE9 W5MRE9 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011958.1|UniProtKB=W5N250 W5N250 PTHR15706:SF2 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005994.1|UniProtKB=W5MFT3 W5MFT3 PTHR23147:SF44 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016504.1|UniProtKB=W5NIC6 W5NIC6 PTHR35072:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;lysosomal transport#GO:0007041 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014816.1|UniProtKB=W5NC85 W5NC85 PTHR24028:SF276 CADHERIN-87A PROTOCADHERIN 20 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000004305.1|UniProtKB=W5M9T7 W5M9T7 PTHR23354:SF120 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1-LIKE ISOFORM X1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;response to oxidative stress#GO:0006979;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005316.1|UniProtKB=W5MDE3 W5MDE3 PTHR43908:SF8 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 12 heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;chaperone cofactor-dependent protein refolding#GO:0051085;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003971.1|UniProtKB=W5M8N4 W5M8N4 PTHR10540:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 translation initiation factor#PC00224;translation factor#PC00223 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000008257.1|UniProtKB=W5MNR4 W5MNR4 PTHR12560:SF43 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 6 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008491.1|UniProtKB=W5MPM5 W5MPM5 GPR65 PTHR24234:SF15 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 65 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007706.1|UniProtKB=W5MLU3 W5MLU3 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018137.1|UniProtKB=W5NNM9 W5NNM9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014603.1|UniProtKB=W5NBH0 W5NBH0 PNCK PTHR24347:SF440 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013970.1|UniProtKB=W5N9B2 W5N9B2 PTHR11224:SF17 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005267.1|UniProtKB=W5MD90 W5MD90 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;transport#GO:0006810;glycolipid metabolic process#GO:0006664;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;Golgi vesicle transport#GO:0048193;GPI anchor metabolic process#GO:0006505;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;localization#GO:0051179;glycerolipid metabolic process#GO:0046486;membrane lipid metabolic process#GO:0006643;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;organophosphate metabolic process#GO:0019637;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011864.1|UniProtKB=W5N1S9 W5N1S9 PTHR34221:SF4 HYPOTHETICAL PROTEIN LOC691189 CHROMOSOME LG9 OPEN READING FRAME, HUMAN C17ORF98 LEPOC|Ensembl=ENSLOCG00000007823.1|UniProtKB=W5MM89 W5MM89 KIF2A PTHR24115:SF486 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012032.1|UniProtKB=W5N2E1 W5N2E1 RPSA PTHR11489:SF9 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000803.1|UniProtKB=W5LXS1 W5LXS1 PTHR13738:SF12 TROPONIN I TROPONIN 1-RELATED blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003246.1|UniProtKB=W5M646 W5M646 PTHR43150:SF7 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-1 binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;channel regulator activity#GO:0016247;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;main axon#GO:0044304;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008120.1|UniProtKB=W5MNA1 W5MNA1 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001563.1|UniProtKB=W5M0D3 W5M0D3 PTHR12011:SF41 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;developmental process#GO:0032502;peripheral nervous system development#GO:0007422;cell communication#GO:0007154;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 p53 pathway#P00059>BAI-1#G04699 LEPOC|Ensembl=ENSLOCG00000010877.1|UniProtKB=W5MY70 W5MY70 PTHR11119:SF57 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 3 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002687.1|UniProtKB=W5M447 W5M447 PTHR10701:SF24 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN N ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 Gonadotropin-releasing hormone receptor pathway#P06664>SNURF#P06808 LEPOC|Ensembl=ENSLOCG00000011130.1|UniProtKB=W5MZ70 W5MZ70 PTHR12231:SF231 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEURAL CELL ADHESION MOLECULE 2 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000003039.1|UniProtKB=W5M5B4 W5M5B4 PTHR10394:SF3 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000857.1|UniProtKB=W5LXW6 W5LXW6 PTHR13800:SF5 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 5 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014287.1|UniProtKB=W5NAD6 W5NAD6 PTHR12354:SF8 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 2 LEPOC|Ensembl=ENSLOCG00000002605.1|UniProtKB=W5M3X6 W5M3X6 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L LEPOC|Ensembl=ENSLOCG00000010802.1|UniProtKB=W5MXY5 W5MXY5 PTHR12680:SF8 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF1 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012234.1|UniProtKB=W5N338 W5N338 PTHR11873:SF1 RETINOL-BINDING PROTEIN 4 PURPURIN transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003189.1|UniProtKB=W5M5W1 W5M5W1 PTHR13601:SF2 GAMETOGENETIN-BINDING PROTEIN 2 GAMETOGENETIN-BINDING PROTEIN 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013225.1|UniProtKB=W5N6N2 W5N6N2 PTHR46096:SF3 PERFORIN-1 PERFORIN-1 wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;cell recognition#GO:0008037;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;T cell mediated immunity#GO:0002456;cell killing#GO:0001906;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;defense response to symbiont#GO:0140546;cell-cell recognition#GO:0009988;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation#GO:0001775;leukocyte mediated cytotoxicity#GO:0001909;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;adaptive immune response#GO:0002250;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;multicellular organismal process#GO:0032501;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;leukocyte activation#GO:0045321 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009556.1|UniProtKB=W5MTH1 W5MTH1 PTHR14058:SF5 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 1 amyloid-beta binding#GO:0001540;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Alzheimer disease-amyloid secretase pathway#P00003>Fe65#P00087;Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 LEPOC|Ensembl=ENSLOCG00000006130.1|UniProtKB=W5MGA2 W5MGA2 PTHR47972:SF5 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN KIFC3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000973.1|UniProtKB=W5LY85 W5LY85 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016196.1|UniProtKB=W5NH55 W5NH55 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000007333.1|UniProtKB=W5MKH2 W5MKH2 PTHR19143:SF225 FIBRINOGEN/TENASCIN/ANGIOPOEITIN MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009816.1|UniProtKB=W5MUD2 W5MUD2 PTHR24133:SF16 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013280.1|UniProtKB=W5N6V3 W5N6V3 PTHR12471:SF3 VACUOLAR ATP SYNTHASE SUBUNIT S1 ATPASE, H+ TRANSPORTING, LYSOSOMAL ACCESSORY PROTEIN 1-LIKE molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 ATPase complex#GO:1904949;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013221.1|UniProtKB=W5N6M8 W5N6M8 PTHR21472:SF16 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000011346.1|UniProtKB=W5MZY9 W5MZY9 PTHR19849:SF0 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A-2-ACTIVATING PROTEIN protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006821.1|UniProtKB=W5MIN7 W5MIN7 PTHR21538:SF21 ANILLIN/RHOTEKIN RTKN RHOTEKIN-2 cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring assembly#GO:0000915;developmental process#GO:0032502;cell cycle process#GO:0022402;positive regulation of cell population proliferation#GO:0008284;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;cytoskeleton-dependent cytokinesis#GO:0061640;hemopoiesis#GO:0030097;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;cytokinesis#GO:0000910;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;regulation of cell population proliferation#GO:0042127;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;actin cytoskeleton organization#GO:0030036;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 actomyosin contractile ring#GO:0005826;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell division site#GO:0032153;contractile ring#GO:0070938;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000014297.1|UniProtKB=W5NAE2 W5NAE2 PTHR18945:SF76 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-5 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotine pharmacodynamics pathway#P06587>CHRNA5#P06593;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000002476.1|UniProtKB=W5M3E8 W5M3E8 PTHR17985:SF8 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG LEPOC|Ensembl=ENSLOCG00000003073.1|UniProtKB=W5M5F9 W5M5F9 PTHR10544:SF0 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003707.1|UniProtKB=W5M7S9 W5M7S9 PTHR45999:SF1 UNC-13-4A, ISOFORM B BAI1-ASSOCIATED PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 regulation of cell communication#GO:0010646;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;positive regulation of secretion by cell#GO:1903532;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;late endosome membrane#GO:0031902;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001525.1|UniProtKB=W5M030 W5M030 TMEM233 PTHR14948:SF19 NG5 TRANSMEMBRANE PROTEIN 233 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008794.1|UniProtKB=W5MQP6 W5MQP6 PTHR12665:SF12 ORMDL PROTEINS ORM1-LIKE PROTEIN 1 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;intracellular chemical homeostasis#GO:0055082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007167.1|UniProtKB=W5MJW2 W5MJW2 PTHR24109:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 LEPOC|Ensembl=ENSLOCG00000012583.1|UniProtKB=W5N4D5 W5N4D5 PTHR11645:SF62 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;oxidoreductase#PC00176 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 LEPOC|Ensembl=ENSLOCG00000011077.1|UniProtKB=W5MYZ0 W5MYZ0 PTHR34648:SF6 CLOCK-INTERACTING PACEMAKER CLOCK-INTERACTING PACEMAKER-RELATED negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005842.1|UniProtKB=W5MF92 W5MF92 PTHR13476:SF0 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000000942.1|UniProtKB=W5LY42 W5LY42 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015323.1|UniProtKB=W5NDZ5 W5NDZ5 PTHR45652:SF13 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT LIGHT POLYPEPTIDE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000004540.1|UniProtKB=W5MAM5 W5MAM5 PTHR43655:SF8 ATP-DEPENDENT PROTEASE PARAPLEGIN mitochondrial protein processing#GO:0034982;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;peptidase complex#GO:1905368;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017243.1|UniProtKB=W5NL18 W5NL18 PTHR14233:SF10 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F1 LEPOC|Ensembl=ENSLOCG00000002363.1|UniProtKB=W5M310 W5M310 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006718.1|UniProtKB=W5MIB0 W5MIB0 PTHR23503:SF22 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 11 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012834.1|UniProtKB=W5N585 W5N585 PTHR46543:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010961.1|UniProtKB=W5MYJ0 W5MYJ0 PTHR11311:SF15 SPONDIN SPONDIN-2 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005245.1|UniProtKB=W5MD60 W5MD60 SDCBP PTHR12345:SF18 SYNTENIN RELATED SYNDECAN-BINDING PROTEIN (SYNTENIN) cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016105.1|UniProtKB=W5NGT3 W5NGT3 PTHR11871:SF2 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B ALPHA ISOFORM phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000016055.1|UniProtKB=W5NGM5 W5NGM5 PTHR37402:SF1 GRAM DOMAIN-CONTAINING PROTEIN 4 GRAM DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000013171.1|UniProtKB=W5N6H2 W5N6H2 PTHR10048:SF99 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000001622.1|UniProtKB=W5M0G4 W5M0G4 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;phosphatidylinositol 3-kinase complex, class III#GO:0035032;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000018193.1|UniProtKB=W5NNT5 W5NNT5 KCNJ15 PTHR11767:SF20 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 15 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007469.1|UniProtKB=W5ML07 W5ML07 PTHR31214:SF3 PROTEIN FAM221A-RELATED PROTEIN FAM221B LEPOC|Ensembl=ENSLOCG00000003751.1|UniProtKB=W5M7V9 W5M7V9 PTHR24368:SF62 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 3 head development#GO:0060322;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000018309.1|UniProtKB=W5NP51 W5NP51 PTHR24028:SF236 CADHERIN-87A PROTOCADHERIN GAMMA-C3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000005611.1|UniProtKB=W5MEG6 W5MEG6 PTHR46507:SF4 AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN SSX FAMILY MEMBER 2 INTERACTING PROTEIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;centriolar satellite#GO:0034451;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000014388.1|UniProtKB=W5NAQ5 W5NAQ5 PTHR45888:SF14 HL01030P-RELATED ZINC FINGER PROTEIN NEURO-D4 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000002160.1|UniProtKB=W5M2B4 W5M2B4 PTHR46947:SF1 WD REPEAT-CONTAINING PROTEIN 73 WD REPEAT-CONTAINING PROTEIN 73 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017158.1|UniProtKB=W5NKP8 W5NKP8 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008817.1|UniProtKB=W5MQT6 W5MQT6 PTHR23192:SF71 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L1-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004866.1|UniProtKB=W5MBT7 W5MBT7 ARMC6 PTHR22895:SF0 ARMADILLO REPEAT-CONTAINING PROTEIN 6 ARMADILLO REPEAT-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000015582.1|UniProtKB=W5NEX6 W5NEX6 PTHR24166:SF27 ROLLING PEBBLES, ISOFORM B CORTACTIN-BINDING PROTEIN 2 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005735.1|UniProtKB=W5MEX0 W5MEX0 PTHR17469:SF1 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN TESPA1 LEPOC|Ensembl=ENSLOCG00000008754.1|UniProtKB=W5MQJ7 W5MQJ7 PTHR14955:SF6 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 RETINOIC ACID-INDUCED PROTEIN 1 circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016258.1|UniProtKB=W5NHE3 W5NHE3 PTHR21255:SF19 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 1 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011758.1|UniProtKB=W5N1E8 W5N1E8 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012923.1|UniProtKB=W5N5K2 W5N5K2 PTHR19282:SF261 TETRASPANIN TETRASPANIN-14 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001787.1|UniProtKB=W5M120 W5M120 PTHR21240:SF27 2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE secondary metabolic process#GO:0019748;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005599.1|UniProtKB=W5MEF2 W5MEF2 PTHR46484:SF7 SI:CH211-171H4.5-RELATED MYELIN-ASSOCIATED GLYCOPROTEIN-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000008097.1|UniProtKB=W5MN78 W5MN78 PTHR45936:SF1 TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004119.1|UniProtKB=W5M984 W5M984 PTHR24412:SF480 KELCH PROTEIN KELCH-LIKE PROTEIN 8 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006349.1|UniProtKB=W5MH03 W5MH03 PTHR24082:SF509 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017631.1|UniProtKB=W5NM77 W5NM77 PTHR24410:SF8 HL07962P-RELATED PEROXISOMAL BIOSIS FACTOR 11 GAMMA defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014045.1|UniProtKB=W5N9K0 W5N9K0 PTHR24237:SF37 G-PROTEIN COUPLED RECEPTOR COAGULATION FACTOR II (THROMBIN) RECEPTOR-LIKE 2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000700.1|UniProtKB=W5LXC1 W5LXC1 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010380.1|UniProtKB=W5MWF8 W5MWF8 CTLA4 PTHR11494:SF8 CYTOTOXIC T-LYMPHOCYTE PROTEIN CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014304.1|UniProtKB=W5NAG1 W5NAG1 PTHR13948:SF4 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017676.1|UniProtKB=W5NMC2 W5NMC2 PTHR23267:SF507 IMMUNOGLOBULIN LIGHT CHAIN T-CELL RECEPTOR ALPHA_DELTA VARIABLE 22.0 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003879.1|UniProtKB=W5M8B9 W5M8B9 PTHR12356:SF3 NUCLEAR MOVEMENT PROTEIN NUDC NUCLEAR MIGRATION PROTEIN NUDC protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014807.1|UniProtKB=W5NC80 W5NC80 PTHR43903:SF4 NEUROLIGIN NEUROLIGIN-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;synaptic vesicle recycling#GO:0036465;membrane assembly#GO:0071709;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;cell-cell signaling#GO:0007267;signaling#GO:0023052;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 cell junction#GO:0030054;cell surface#GO:0009986;synapse#GO:0045202;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004391.1|UniProtKB=W5MA37 W5MA37 PTHR11145:SF14 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;negative regulation of small GTPase mediated signal transduction#GO:0051058;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;regulation of small GTPase mediated signal transduction#GO:0051056;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009306.1|UniProtKB=W5MSJ4 W5MSJ4 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000010178.1|UniProtKB=W5MVQ1 W5MVQ1 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007624.1|UniProtKB=W5MLJ0 W5MLJ0 PTHR43289:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE-PROTEIN KINASE NEK7 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013423.1|UniProtKB=W5N7E2 W5N7E2 PTHR46209:SF1 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-11 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014194.1|UniProtKB=W5NA32 W5NA32 PTHR18861:SF3 ELKS/RAB6-INTERACTING/CAST PROTEIN ERC PROTEIN 2 structural molecule activity#GO:0005198 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;neuromuscular synaptic transmission#GO:0007274;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004336.1|UniProtKB=W5M9Y1 W5M9Y1 PAN3 PTHR12272:SF11 DEADENYLATION COMPLEX SUBUNIT PAN3 PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000005036.1|UniProtKB=W5MCH2 W5MCH2 PTHR24153:SF14 ESPIN ESPIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament bundle organization#GO:0061572 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005039.1|UniProtKB=W5MCF8 W5MCF8 PTHR23010:SF1 MIDNOLIN MIDNOLIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002893.1|UniProtKB=W5M4V1 W5M4V1 PTHR24061:SF358 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of metal ion transport#GO:0010959;regulation of calcium ion transport#GO:0051924;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;regulation of localization#GO:0032879;detection of stimulus#GO:0051606;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;detection of chemical stimulus#GO:0009593;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;response to chemical#GO:0042221;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;intracellular monoatomic ion homeostasis#GO:0006873 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009071.1|UniProtKB=W5MRP2 W5MRP2 PTHR22948:SF19 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007860.1|UniProtKB=W5MME7 W5MME7 PRPF38B PTHR23142:SF2 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38B ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010738.1|UniProtKB=W5MXP9 W5MXP9 PTHR24342:SF6 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001271.1|UniProtKB=W5LZ98 W5LZ98 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;negative regulation of translation#GO:0017148;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000001580.1|UniProtKB=W5M0A4 W5M0A4 PTHR11866:SF31 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cytosolic calcium ion concentration#GO:0007204;response to lipid#GO:0033993;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;defense response#GO:0006952;signaling#GO:0023052;response to organic substance#GO:0010033;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of response to stress#GO:0080134;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012270.1|UniProtKB=W5N389 W5N389 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008953.1|UniProtKB=W5MRA4 W5MRA4 PTHR45817:SF5 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014582.1|UniProtKB=W5NBD4 W5NBD4 PTHR24241:SF127 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 22-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000298.1|UniProtKB=W5LW21 W5LW21 PTHR10337:SF6 SHC TRANSFORMING PROTEIN CENTROSOMAL PROTEIN OF 152 KDA scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011197.1|UniProtKB=W5MZF4 W5MZF4 COL25A1 PTHR37456:SF3 SI:CH211-266K2.1 COLLAGEN ALPHA-1(XXV) CHAIN LEPOC|Ensembl=ENSLOCG00000015469.1|UniProtKB=W5NEI0 W5NEI0 PTHR18887:SF2 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012031.1|UniProtKB=W5N2E0 W5N2E0 PTHR10159:SF309 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;endoderm formation#GO:0001706;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;regulation of cellular process#GO:0050794;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;embryonic morphogenesis#GO:0048598 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131;Gonadotropin-releasing hormone receptor pathway#P06664>DUSP1#P06823;p38 MAPK pathway#P05918>MKP1#P05922 LEPOC|Ensembl=ENSLOCG00000017346.1|UniProtKB=W5NLE2 W5NLE2 PTHR10270:SF231 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;head development#GO:0060322;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000003104.1|UniProtKB=W5M5J4 W5M5J4 PTHR14191:SF4 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012969.1|UniProtKB=W5N5R4 W5N5R4 PTHR18945:SF489 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000006160.1|UniProtKB=W5MGE7 W5MGE7 PTHR11206:SF268 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015458.1|UniProtKB=W5NEG5 W5NEG5 PTHR24241:SF164 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RFAMIDE PEPTIDE RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012633.1|UniProtKB=W5N4I9 W5N4I9 PTHR10156:SF0 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009722.1|UniProtKB=W5MU14 W5MU14 CCKAR PTHR24238:SF81 G-PROTEIN COUPLED RECEPTOR CHOLECYSTOKININ RECEPTOR TYPE A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013982.1|UniProtKB=W5N9D2 W5N9D2 PTHR12659:SF2 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 7 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000003474.1|UniProtKB=W5M6X6 W5M6X6 PTHR48012:SF22 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 24 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;macromolecule modification#GO:0043412;regulation of locomotion#GO:0040012;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;negative regulation of cell motility#GO:2000146;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003346.1|UniProtKB=W5M6E4 W5M6E4 PTHR21630:SF10 VEPH-A/MELTED VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009561.1|UniProtKB=W5MTH6 W5MTH6 C9orf85 PTHR22876:SF5 ZGC:101016 CHROMOSOME 9 OPEN READING FRAME 85 LEPOC|Ensembl=ENSLOCG00000012513.1|UniProtKB=W5N444 W5N444 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000002907.1|UniProtKB=W5M4V7 W5M4V7 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 negative regulation of biological process#GO:0048519;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;protein folding#GO:0006457;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CCKR signaling map#P06959>HSP27#P07154;VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231;p38 MAPK pathway#P05918>HSP27#P06016 LEPOC|Ensembl=ENSLOCG00000001574.1|UniProtKB=W5M0B6 W5M0B6 PTHR42861:SF2 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000818.1|UniProtKB=W5LXQ2 W5LXQ2 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX_WD REPEAT-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000010181.1|UniProtKB=W5MVR0 W5MVR0 PTHR12419:SF10 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTUD6B cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003709.1|UniProtKB=W5M7Q9 W5M7Q9 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 LEPOC|Ensembl=ENSLOCG00000003846.1|UniProtKB=W5M895 W5M895 PTHR21576:SF2 UNCHARACTERIZED NODULIN-LIKE PROTEIN RRP12-LIKE PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004912.1|UniProtKB=W5MC00 W5MC00 PTHR14555:SF1 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED MELANOPHILIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;actin binding#GO:0003779;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007893.1|UniProtKB=W5MMH7 W5MMH7 RNF180 PTHR46717:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF180 E3 UBIQUITIN-PROTEIN LIGASE RNF180 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;biogenic amine metabolic process#GO:0006576;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;catecholamine metabolic process#GO:0006584;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;regulation of proteolysis#GO:0030162;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007138.1|UniProtKB=W5MJT1 W5MJT1 PTHR31402:SF2 UPF0711 PROTEIN C18ORF21 UPF0711 PROTEIN C18ORF21 LEPOC|Ensembl=ENSLOCG00000012455.1|UniProtKB=W5N3Y2 W5N3Y2 PTHR15427:SF40 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER MULTIMERIN-2 PRECURSOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013297.1|UniProtKB=W5N6X3 W5N6X3 RAMP3 PTHR14076:SF2 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;import into cell#GO:0098657 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007506.1|UniProtKB=W5ML50 W5ML50 PTHR43775:SF37 FATTY ACID SYNTHASE SI:DKEY-61P9.11 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000013967.1|UniProtKB=W5N9B0 W5N9B0 PTHR10856:SF17 CORONIN CORONIN-2B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003905.1|UniProtKB=W5M8G8 W5M8G8 PTHR10605:SF10 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011355.1|UniProtKB=W5MZZ7 W5MZZ7 PTHR12352:SF25 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC_OSTEONECTIN, CWCV AND KAZAL LIKE DOMAINS PROTEOGLYCAN 1 localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184;protein localization#GO:0008104 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010349.1|UniProtKB=W5MWC5 W5MWC5 PTHR24340:SF101 HOMEOBOX PROTEIN NKX TRANSCRIPTION FACTOR SOHO sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004429.1|UniProtKB=W5MA84 W5MA84 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16 catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016429.1|UniProtKB=W5NI33 W5NI33 PTHR45832:SF4 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000002844.1|UniProtKB=W5M4N5 W5M4N5 PTHR45787:SF3 LD11652P RHOMBOTIN-2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014453.1|UniProtKB=W5NAX9 W5NAX9 PTHR10574:SF383 NETRIN/LAMININ-RELATED NETRIN 5 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000007442.1|UniProtKB=W5MKX8 W5MKX8 PTHR12308:SF15 ANOCTAMIN ANOCTAMIN inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017155.1|UniProtKB=W5NKP1 W5NKP1 FIG4 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011458.1|UniProtKB=W5N0B9 W5N0B9 PTHR24168:SF19 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 regulation of anatomical structure size#GO:0090066;negative regulation of protein polymerization#GO:0032272;negative regulation of biological process#GO:0048519;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008084.1|UniProtKB=W5MN71 W5MN71 PTHR33721:SF4 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255B LEPOC|Ensembl=ENSLOCG00000011014.1|UniProtKB=W5MYR2 W5MYR2 PTHR22600:SF38 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT BETA hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;macromolecule metabolic process#GO:0043170;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010031.1|UniProtKB=W5MV62 W5MV62 ANKS1A PTHR24174:SF4 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 1A protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011367.1|UniProtKB=W5N011 W5N011 PTHR22978:SF29 B-CELL TRANSLOCATION GENE PROTEIN BTG2 biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017002.1|UniProtKB=W5NK57 W5NK57 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017911.1|UniProtKB=W5NN05 W5NN05 PTHR24365:SF539 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005480.1|UniProtKB=W5ME00 W5ME00 PTHR10283:SF82 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005241.1|UniProtKB=W5MD54 W5MD54 PTHR19288:SF92 4-NITROPHENYLPHOSPHATASE-RELATED GLYCEROL-3-PHOSPHATE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000020993.1|UniProtKB=Q8HQM4 Q8HQM4 ND4 PTHR43507:SF20 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954;small molecule binding#GO:0036094;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001711.1|UniProtKB=W5M0R8 W5M0R8 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009040.1|UniProtKB=W5MRL8 W5MRL8 PTHR12187:SF3 AGAP000124-PA INOSITOL POLYPHOSPHATE 4-PHOSPHATASE TYPE II hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014379.1|UniProtKB=W5NAP8 W5NAP8 PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN protein-containing complex binding#GO:0044877;binding#GO:0005488 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;import into cell#GO:0098657;endocytosis#GO:0006897;transport#GO:0006810 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013800.1|UniProtKB=W5N8Q6 W5N8Q6 C4orf47 PTHR31144:SF1 UPF0602 PROTEIN C4ORF47 UPF0602 PROTEIN C4ORF47 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008926.1|UniProtKB=W5MR58 W5MR58 PTHR12936:SF0 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Cell cycle#P00013>APC#P00481 LEPOC|Ensembl=ENSLOCG00000013572.1|UniProtKB=W5N7X1 W5N7X1 TNS4 PTHR45734:SF3 TENSIN TENSIN-1 ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000009921.1|UniProtKB=W5MUS3 W5MUS3 WDR1 PTHR19856:SF0 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;protein-containing complex disassembly#GO:0032984;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament depolymerization#GO:0030042 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000000684.1|UniProtKB=W5LXA0 W5LXA0 PTHR24070:SF385 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE HRAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;FGF signaling pathway#P00021>Ras#P00633;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Angiogenesis#P00005>Ras#P00238;T cell activation#P00053>Ras#P01306;B cell activation#P00010>Ras#P00376;Gonadotropin-releasing hormone receptor pathway#P06664>Ras#P06753;Ras Pathway#P04393>Ras#P04547;PI3 kinase pathway#P00048>Ras#P01182;p53 pathway feedback loops 2#P04398>Ras#P04651;Integrin signalling pathway#P00034>Ras#P00916;VEGF signaling pathway#P00056>Ras#P01411 LEPOC|Ensembl=ENSLOCG00000006123.1|UniProtKB=W5MG92 W5MG92 PTHR12857:SF0 CXXC MOTIF CONTAINING ZINC BINDING PROTEIN CXXC MOTIF CONTAINING ZINC BINDING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 LEPOC|Ensembl=ENSLOCG00000012956.1|UniProtKB=W5N5Q0 W5N5Q0 NSUN7 PTHR14663:SF2 METHYLTRANSFERASE NSUN7-RELATED METHYLTRANSFERASE NSUN7-RELATED LEPOC|Ensembl=ENSLOCG00000017663.1|UniProtKB=W5NMA9 W5NMA9 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010049.1|UniProtKB=W5MV83 W5MV83 PTHR11683:SF10 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-B structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;gliogenesis#GO:0042063;cellular component organization#GO:0016043;cellular process#GO:0009987;oligodendrocyte differentiation#GO:0048709;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;glial cell differentiation#GO:0010001;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;generation of neurons#GO:0048699;myelination#GO:0042552 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000001917.1|UniProtKB=W5M1G7 W5M1G7 TMEM132C PTHR13388:SF28 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C LEPOC|Ensembl=ENSLOCG00000004552.1|UniProtKB=W5MAN9 W5MAN9 PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;biological regulation#GO:0065007;signal release#GO:0023061;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;cell-cell signaling#GO:0007267;signaling#GO:0023052;export from cell#GO:0140352;secretion by cell#GO:0032940 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000006211.1|UniProtKB=W5MGJ2 W5MGJ2 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000011817.1|UniProtKB=W5N1M0 W5N1M0 PTHR11849:SF21 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-4 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>ELK#P00962;CCKR signaling map#P06959>SAP1#P07097;PDGF signaling pathway#P00047>ELK#P01140 LEPOC|Ensembl=ENSLOCG00000002045.1|UniProtKB=W5M1W8 W5M1W8 PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;four-way junction DNA binding#GO:0000400 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014247.1|UniProtKB=W5NA82 W5NA82 PTHR15283:SF3 GREMLIN 1 GREMLIN-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;animal organ development#GO:0048513;developmental process#GO:0032502;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014424.1|UniProtKB=W5NAU4 W5NAU4 PTHR45704:SF11 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11A-LIKE LEPOC|Ensembl=ENSLOCG00000000953.1|UniProtKB=W5LY55 W5LY55 PTHR11994:SF8 60S RIBOSOMAL PROTEIN L11-RELATED 60S RIBOSOMAL PROTEIN L11 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007938.1|UniProtKB=W5MMM8 W5MMM8 PTHR45981:SF1 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;MHC protein binding#GO:0042287;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;immune response#GO:0006955;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;antigen processing and presentation#GO:0019882;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000005923.1|UniProtKB=W5MFJ4 W5MFJ4 PTHR13468:SF1 DEK PROTEIN PROTEIN DEK protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of DNA metabolic process#GO:0051052;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014352.1|UniProtKB=W5NAL4 W5NAL4 PTHR46512:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE negative regulation of biological process#GO:0048519;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 envelope#GO:0031975;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007859.1|UniProtKB=W5MME2 W5MME2 PTHR21139:SF2 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;carbohydrate derivative biosynthetic process#GO:1901137;hexose biosynthetic process#GO:0019319;small molecule catabolic process#GO:0044282;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Triosephosphate isomerase#P00673 LEPOC|Ensembl=ENSLOCG00000008895.1|UniProtKB=W5MR26 W5MR26 CEP128 PTHR46657:SF1 CENTROSOMAL PROTEIN OF 128 KDA CENTROSOMAL PROTEIN OF 128 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004568.1|UniProtKB=W5MAR5 W5MAR5 PTHR22847:SF637 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B LEPOC|Ensembl=ENSLOCG00000017195.1|UniProtKB=W5NKU5 W5NKU5 SDC1 PTHR10915:SF5 SYNDECAN SYNDECAN-1 cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014446.1|UniProtKB=W5NAX1 W5NAX1 PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED WASP ACTIN NUCLEATION-PROMOTING FACTOR A-RELATED actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011751.1|UniProtKB=W5N1D9 W5N1D9 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001534.1|UniProtKB=W5M054 W5M054 PTHR10504:SF84 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BACTERICIDAL PERMEABILITY-INCREASING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016923.1|UniProtKB=W5NJW0 W5NJW0 PTHR14274:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 8 SMALL INTEGRAL MEMBRANE PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000014400.1|UniProtKB=W5NAS1 W5NAS1 PTHR11685:SF210 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH2 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008697.1|UniProtKB=W5MQB9 W5MQB9 PTHR34914:SF1 LYMPHOCYTE EXPANSION MOLECULE LYMPHOCYTE EXPANSION MOLECULE LEPOC|Ensembl=ENSLOCG00000010397.1|UniProtKB=W5MWJ0 W5MWJ0 PTHR23382:SF1 MALATE DEHYDROGENASE MALATE DEHYDROGENASE 1B-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;dicarboxylic acid metabolic process#GO:0043648;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014449.1|UniProtKB=W5NAZ2 W5NAZ2 PTHR10749:SF4 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, SKELETAL MUSCLE ISOFORM cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000007680.1|UniProtKB=W5MLR4 W5MLR4 PTHR10715:SF0 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008376.1|UniProtKB=W5MP68 W5MP68 PTHR24366:SF129 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 24 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000009692.1|UniProtKB=W5MTX7 W5MTX7 SNX31 PTHR12431:SF15 SORTING NEXIN 17 AND 27 SORTING NEXIN-31 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004419.1|UniProtKB=W5MA69 W5MA69 PTHR11850:SF89 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1 head development#GO:0060322;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;embryonic organ development#GO:0048568;cell differentiation#GO:0030154;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;visual system development#GO:0150063;sensory system development#GO:0048880;generation of neurons#GO:0048699;sensory organ development#GO:0007423 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>Pbx1#P06729 LEPOC|Ensembl=ENSLOCG00000008233.1|UniProtKB=W5MNN8 W5MNN8 PTHR24416:SF132 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;Wnt-protein binding#GO:0017147;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013689.1|UniProtKB=W5N8B6 W5N8B6 PTHR10825:SF31 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 2 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000009030.1|UniProtKB=W5MRJ6 W5MRJ6 PTHR24103:SF639 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM39 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012465.1|UniProtKB=W5N3Y7 W5N3Y7 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009195.1|UniProtKB=W5MS63 W5MS63 PTHR12299:SF30 HYALURONIC ACID-BINDING PROTEIN 4 INTRACELLULAR HYALURONAN-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of translational initiation#GO:0006446;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013339.1|UniProtKB=W5N742 W5N742 PTHR11932:SF169 CULLIN CULLIN 1 enzyme binding#GO:0019899;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Cul-1#P01239 LEPOC|Ensembl=ENSLOCG00000013722.1|UniProtKB=W5N8G3 W5N8G3 PTHR43161:SF9 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007589.1|UniProtKB=W5MLE9 W5MLE9 PTHR24255:SF29 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT COMPONENT 1, S SUBCOMPONENT hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016003.1|UniProtKB=W5NGE9 W5NGE9 PTHR24241:SF146 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002950.1|UniProtKB=W5M551 W5M551 PTHR23421:SF199 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 galactosidase#PC00104;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017906.1|UniProtKB=W5NN00 W5NN00 PTHR24366:SF73 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL 3A cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000012935.1|UniProtKB=W5N5M0 W5N5M0 PTHR19290:SF9 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014012.1|UniProtKB=W5N9G5 W5N9G5 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000018211.1|UniProtKB=W5NNV3 W5NNV3 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014104.1|UniProtKB=W5N9R6 W5N9R6 PTHR24125:SF0 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A LEPOC|Ensembl=ENSLOCG00000011092.1|UniProtKB=W5MZ22 W5MZ22 PTHR10527:SF21 IMPORTIN BETA TRANSPORTIN-1 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013314.1|UniProtKB=W5N6Z8 W5N6Z8 PTHR12757:SF5 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017467.1|UniProtKB=W5NLR3 W5NLR3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014354.1|UniProtKB=W5NAM0 W5NAM0 PTHR11616:SF126 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007638.1|UniProtKB=W5MLL0 W5MLL0 RPH3A PTHR45729:SF3 RABPHILIN, ISOFORM A RABPHILIN-3A neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cell communication#GO:0007154;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;signal release from synapse#GO:0099643;exocytosis#GO:0006887;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of exocytosis#GO:0017157;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;transport vesicle membrane#GO:0030658;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011483.1|UniProtKB=W5N0F3 W5N0F3 PTHR22765:SF40 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF130 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001161.1|UniProtKB=W5LYV0 W5LYV0 OXT PTHR11681:SF5 NEUROPHYSIN ISOTOCIN neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;secretory vesicle#GO:0099503;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 neuropeptide#PC00162;peptide hormone#PC00179 Opioid prodynorphin pathway#P05916>provasopressin#P05999;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Signal Peptide#P04597;Opioid prodynorphin pathway#P05916>vasopressin#P06000;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>prepropressophysin#G06048;Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Vasopressin synthesis#P04395>Glycopeptide#P04593;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595;Vasopressin synthesis#P04395>Neurophysin#P04594 LEPOC|Ensembl=ENSLOCG00000001544.1|UniProtKB=W5M092 W5M092 PTHR24023:SF714 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;kidney development#GO:0001822;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000009625.1|UniProtKB=W5MTQ2 W5MTQ2 PTHR12970:SF1 PROTEASOME ASSEMBLY CHAPERONE 2 PROTEASOME ASSEMBLY CHAPERONE 2 protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007946.1|UniProtKB=W5MMP1 W5MMP1 TEX36 PTHR35440:SF1 TESTIS-EXPRESSED PROTEIN 36 TESTIS-EXPRESSED PROTEIN 36 LEPOC|Ensembl=ENSLOCG00000006857.1|UniProtKB=W5MIT3 W5MIT3 PTHR22750:SF38 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017439.1|UniProtKB=W5NLN5 W5NLN5 PTHR45961:SF5 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000011299.1|UniProtKB=W5MZS7 W5MZS7 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001695.1|UniProtKB=W5M0P8 W5M0P8 PTHR10127:SF883 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ZINC METALLOPROTEINASE NAS-8 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007655.1|UniProtKB=W5MLN5 W5MLN5 PTHR12630:SF20 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;liver development#GO:0001889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;primary metabolic process#GO:0044238;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015046.1|UniProtKB=W5ND10 W5ND10 PTHR11636:SF80 POU DOMAIN HIGHLY DIVERGENT HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011915.1|UniProtKB=W5N1Z1 W5N1Z1 PTHR18957:SF0 CENTLEIN CENTLEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;protein localization to organelle#GO:0033365 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017560.1|UniProtKB=W5NM06 W5NM06 PTHR24232:SF108 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 35-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005837.1|UniProtKB=W5MF93 W5MF93 PTHR18945:SF60 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT GAMMA monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>gamma#P01094;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000003210.1|UniProtKB=W5M5Y6 W5M5Y6 PTHR14627:SF0 TRANSMEMBRANE PROTEIN 204 TRANSMEMBRANE PROTEIN 204 LEPOC|Ensembl=ENSLOCG00000015838.1|UniProtKB=W5NFT9 W5NFT9 PTHR10306:SF33 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE 1 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016346.1|UniProtKB=W5NHS6 W5NHS6 CRISP1 PTHR10334:SF568 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE RICH SECRETORY PROTEIN 3 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001745.1|UniProtKB=W5M102 W5M102 PTHR18916:SF6 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 LEPOC|Ensembl=ENSLOCG00000007408.1|UniProtKB=W5MKS9 W5MKS9 PTHR36427:SF3 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013056.1|UniProtKB=W5N620 W5N620 TMEM43 PTHR13416:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 43 lipid metabolic process#GO:0006629;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000000539.1|UniProtKB=W5LWT9 W5LWT9 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000018284.1|UniProtKB=W5NP26 W5NP26 PTHR46272:SF4 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008451.1|UniProtKB=W5MPH2 W5MPH2 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;rRNA binding#GO:0019843;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004194.1|UniProtKB=W5M9F1 W5M9F1 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005906.1|UniProtKB=W5MFI1 W5MFI1 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;phosphatidylinositol 3-kinase complex, class III#GO:0035032;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007627.1|UniProtKB=W5MLJ4 W5MLJ4 PTHR43313:SF36 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012170.1|UniProtKB=W5N2V9 W5N2V9 PTHR12223:SF36 VESICULAR MANNOSE-BINDING LECTIN VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488;monosaccharide binding#GO:0048029 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014955.1|UniProtKB=W5NCQ5 W5NCQ5 PTHR24238:SF57 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 83 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011290.1|UniProtKB=W5MZR9 W5MZR9 ST6GALNAC1 PTHR45941:SF1 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 carbohydrate biosynthetic process#GO:0016051;oligosaccharide biosynthetic process#GO:0009312;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000001761.1|UniProtKB=W5M0X5 W5M0X5 PTHR31786:SF2 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 protein-containing complex#GO:0032991;Fanconi anaemia nuclear complex#GO:0043240;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012471.1|UniProtKB=W5N3Z5 W5N3Z5 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016737.1|UniProtKB=W5NJ80 W5NJ80 BEND7 PTHR35068:SF1 BEN DOMAIN-CONTAINING PROTEIN 7 BEN DOMAIN-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000018082.1|UniProtKB=W5NNH4 W5NNH4 PTHR11214:SF3 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 6 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;Golgi membrane#GO:0000139;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007402.1|UniProtKB=W5MKT5 W5MKT5 PTHR15829:SF15 PROTEIN KINASE PKN/PRK1, EFFECTOR RIPOR FAMILY MEMBER 3 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005766.1|UniProtKB=W5MF06 W5MF06 PTHR24229:SF1 NEUROPEPTIDES RECEPTOR KAPPA-TYPE OPIOID RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Opioid prodynorphin pathway#P05916>Kappa Receptor#P05998 LEPOC|Ensembl=ENSLOCG00000003746.1|UniProtKB=W5M7X3 W5M7X3 PTHR13586:SF1 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG B nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;non-membrane-bounded organelle assembly#GO:0140694;P-body assembly#GO:0033962;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010063.1|UniProtKB=W5MV98 W5MV98 PTHR15228:SF36 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 24-LIKE ISOFORM X1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 negative regulation of biological process#GO:0048519;regulation of plasma membrane bounded cell projection assembly#GO:0120032;epithelium development#GO:0060429;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;activation of GTPase activity#GO:0090630;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;wound healing#GO:0042060;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;negative regulation of small GTPase mediated signal transduction#GO:0051058;regulation of hydrolase activity#GO:0051336;negative regulation of cellular component organization#GO:0051129;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;negative regulation of signaling#GO:0023057;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;negative regulation of signal transduction#GO:0009968;cell migration#GO:0016477 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000011491.1|UniProtKB=W5N0G3 W5N0G3 PTHR12369:SF20 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007227.1|UniProtKB=W5MK47 W5MK47 PTHR12687:SF4 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000005726.1|UniProtKB=W5MEY9 W5MEY9 PTHR12546:SF55 FER-1-LIKE MYOFERLIN endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;membrane fusion#GO:0061025;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003987.1|UniProtKB=W5M8T7 W5M8T7 PTHR43184:SF11 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A1 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;inorganic anion transport#GO:0015698 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012052.1|UniProtKB=W5N2G4 W5N2G4 PTHR48099:SF7 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE 2, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 LEPOC|Ensembl=ENSLOCG00000005139.1|UniProtKB=W5MCT3 W5MCT3 MSANTD2 PTHR46933:SF1 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004528.1|UniProtKB=W5MAK8 W5MAK8 PTHR21345:SF9 SPIRE KIND DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell division#GO:0051301;organelle localization#GO:0051640;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament organization#GO:0007015;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;spindle localization#GO:0051653;multicellular organismal reproductive process#GO:0048609;cellular component assembly#GO:0022607;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;vesicle-mediated transport#GO:0016192;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of spindle localization#GO:0051293;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001381.1|UniProtKB=W5LZL7 W5LZL7 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017918.1|UniProtKB=W5NN12 W5NN12 PTHR24248:SF117 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004231.1|UniProtKB=W5M9K5 W5M9K5 PTHR12172:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD17 CELL CYCLE CHECKPOINT PROTEIN RAD17 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;mitotic DNA replication checkpoint signaling#GO:0033314;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of mitotic cell cycle#GO:0045930;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA integrity checkpoint signaling#GO:0044774;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 LEPOC|Ensembl=ENSLOCG00000016071.1|UniProtKB=W5NGP3 W5NGP3 PTHR48078:SF14 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000006800.1|UniProtKB=W5MIL0 W5MIL0 PTHR20931:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 30 TETRATRICOPEPTIDE REPEAT PROTEIN 30 protein-containing complex binding#GO:0044877;binding#GO:0005488 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;axonemal microtubule#GO:0005879 LEPOC|Ensembl=ENSLOCG00000013254.1|UniProtKB=W5N6T1 W5N6T1 PTHR15593:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p101#P01203;Axon guidance mediated by netrin#P00009>PI3K#P00363;EGF receptor signaling pathway#P00018>PI3K#P00557;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900 LEPOC|Ensembl=ENSLOCG00000004225.1|UniProtKB=W5M9J3 W5M9J3 PTHR11567:SF110 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000012609.1|UniProtKB=W5N4F7 W5N4F7 PTHR11256:SF11 BCL-2 RELATED APOPTOSIS REGULATOR BCL-2 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Oxidative stress response#P00046>Bcl-2#P01123;CCKR signaling map#P06959>BCL2#P07059;Apoptosis signaling pathway#P00006>Bcl-2#P00270 LEPOC|Ensembl=ENSLOCG00000009471.1|UniProtKB=W5MT71 W5MT71 RIMS2 PTHR12157:SF15 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 LEPOC|Ensembl=ENSLOCG00000007947.1|UniProtKB=W5MMP2 W5MMP2 PTHR11387:SF2 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001360.1|UniProtKB=W5LZJ2 W5LZJ2 PTHR46012:SF3 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 1 UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000009995.1|UniProtKB=W5MV17 W5MV17 PTHR13123:SF6 LD30288P F-BOX ONLY PROTEIN 32 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015966.1|UniProtKB=W5NGA0 W5NGA0 PTHR12573:SF4 AT09986P-RELATED AT09986P-RELATED LEPOC|Ensembl=ENSLOCG00000011170.1|UniProtKB=W5MZB5 W5MZB5 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN MS25 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005034.1|UniProtKB=W5MCF3 W5MCF3 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008021.1|UniProtKB=W5MMY9 W5MMY9 PTHR12917:SF13 ASPARTYL PROTEASE DDI-RELATED PROTEIN DDI1 HOMOLOG 2 aspartic protease#PC00053;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005720.1|UniProtKB=W5MEU3 W5MEU3 PTHR16231:SF2 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 7 NF-kappaB binding#GO:0051059;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to cytokine#GO:0034097;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;negative regulation of DNA-templated transcription#GO:0045892;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of DNA-binding transcription factor activity#GO:0051090;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;tumor necrosis factor-mediated signaling pathway#GO:0033209;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;response to tumor necrosis factor#GO:0034612;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;negative regulation of DNA-binding transcription factor activity#GO:0043433 LEPOC|Ensembl=ENSLOCG00000000212.1|UniProtKB=W5LVS9 W5LVS9 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017345.1|UniProtKB=W5NLE1 W5NLE1 PTHR24231:SF35 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 4-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009061.1|UniProtKB=W5MRN9 W5MRN9 PTHR23180:SF402 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010419.1|UniProtKB=W5MWL7 W5MWL7 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005920.1|UniProtKB=W5MFK4 W5MFK4 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000011708.1|UniProtKB=W5N191 W5N191 PTHR45589:SF4 WD REPEAT DOMAIN 62, ISOFORM G MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;centriole assembly#GO:0098534;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007232.1|UniProtKB=W5MK42 W5MK42 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL ATP synthesis#P02721>Cyt bc1#P02799;FAS signaling pathway#P00020>CytochromeC#P00620;Huntington disease#P00029>Cytochrome c#P00785 LEPOC|Ensembl=ENSLOCG00000005543.1|UniProtKB=W5ME82 W5ME82 XKR4 PTHR16024:SF16 XK-RELATED PROTEIN XK-RELATED PROTEIN 4 execution phase of apoptosis#GO:0097194;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;programmed cell death#GO:0012501;phospholipid transport#GO:0015914;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;biological regulation#GO:0065007;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016121.1|UniProtKB=W5NGW2 W5NGW2 PTHR12301:SF3 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001549.1|UniProtKB=W5M098 W5M098 PTHR12062:SF4 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000930.1|UniProtKB=W5LY49 W5LY49 MYH6 PTHR13140:SF857 MYOSIN MYOSIN-11 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000000954.1|UniProtKB=W5LY62 W5LY62 SEC14L5 PTHR23324:SF39 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 5 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014571.1|UniProtKB=W5NBC6 W5NBC6 PTHR18945:SF907 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000005271.1|UniProtKB=W5MD95 W5MD95 PTHR13196:SF22 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1A lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007933.1|UniProtKB=W5MMM5 W5MMM5 PTHR22792:SF166 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015301.1|UniProtKB=W5NDW5 W5NDW5 PTHR21559:SF24 DYSTROGLYCAN-RELATED DYSTROGLYCAN 1 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;muscle organ development#GO:0007517;neurogenesis#GO:0022008;cell projection organization#GO:0030030;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004226.1|UniProtKB=W5M9J5 W5M9J5 PTHR24103:SF695 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-18P12.4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011212.1|UniProtKB=W5MZG4 W5MZG4 PTHR21245:SF4 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN DEAD END PROTEIN HOMOLOG 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017319.1|UniProtKB=W5NLB5 W5NLB5 PTHR15478:SF8 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 2 LEPOC|Ensembl=ENSLOCG00000006210.1|UniProtKB=W5MGJ4 W5MGJ4 CEP164 PTHR18902:SF27 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED CENTROSOMAL PROTEIN OF 164 KDA organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;ciliary transition fiber#GO:0097539;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007833.1|UniProtKB=W5MMA0 W5MMA0 PTHR15821:SF0 PROTEIN MN1 TRANSCRIPTIONAL ACTIVATOR MN1 LEPOC|Ensembl=ENSLOCG00000002489.1|UniProtKB=W5M3G3 W5M3G3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017510.1|UniProtKB=W5NLV6 W5NLV6 GJC1 PTHR11984:SF6 CONNEXIN GAP JUNCTION GAMMA-1 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000001414.1|UniProtKB=W5LZQ7 W5LZQ7 PTHR12247:SF69 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003137.1|UniProtKB=W5M5N4 W5M5N4 PTHR11640:SF158 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001660.1|UniProtKB=W5M0K6 W5M0K6 PTHR10686:SF19 FOLATE TRANSPORTER THIAMINE TRANSPORTER 1 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005104.1|UniProtKB=W5MCP8 W5MCP8 KDM2B PTHR23123:SF10 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2B histone modifying activity#GO:0140993;molecular adaptor activity#GO:0060090;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000017790.1|UniProtKB=W5NMN5 W5NMN5 PTHR11984:SF19 CONNEXIN GAP JUNCTION ALPHA-8 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000001945.1|UniProtKB=W5M1J2 W5M1J2 IGSF22 PTHR13817:SF153 TITIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 22 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001321.1|UniProtKB=W5LZG4 W5LZG4 PTHR24006:SF682 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002834.1|UniProtKB=W5M4M1 W5M4M1 PTHR10458:SF2 PEPTIDE DEFORMYLASE PEPTIDE DEFORMYLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009029.1|UniProtKB=W5MRJ8 W5MRJ8 PTHR24006:SF852 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016373.1|UniProtKB=W5NHV5 W5NHV5 PTHR10390:SF31 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;sensory system development#GO:0048880;visual system development#GO:0150063;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009217.1|UniProtKB=W5MS87 W5MS87 PTHR11132:SF262 SOLUTE CARRIER FAMILY 35 UDP-N-ACETYLGLUCOSAMINE_UDP-GLUCOSE_GDP-MANNOSE TRANSPORTER carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010458.1|UniProtKB=W5MWT5 W5MWT5 PTHR11920:SF505 GUANYLYL CYCLASE GUANYLATE CYCLASE adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;peptide hormone binding#GO:0017046;phosphorus-oxygen lyase activity#GO:0016849;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;hormone binding#GO:0042562 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000006305.1|UniProtKB=W5MGV5 W5MGV5 PTHR13271:SF34 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE N-LYSINE METHYLTRANSFERASE SETD6 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012768.1|UniProtKB=W5N500 W5N500 PTHR14340:SF2 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRILLAR-ASSOCIATED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000000888.1|UniProtKB=W5LY29 W5LY29 PTHR11254:SF66 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;protein K63-linked ubiquitination#GO:0070534;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000008670.1|UniProtKB=W5MQC6 W5MQC6 PTHR24025:SF18 DESMOGLEIN FAMILY MEMBER CADHERIN-23 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000017916.1|UniProtKB=W5NN10 W5NN10 PTHR24241:SF182 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 19 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008212.1|UniProtKB=W5MNL1 W5MNL1 PTHR12932:SF16 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012720.1|UniProtKB=W5N4V2 W5N4V2 PTHR10663:SF340 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-1 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017095.1|UniProtKB=W5NKH3 W5NKH3 AKR1B1 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005071.1|UniProtKB=W5MCJ8 W5MCJ8 PTHR21166:SF2 CELL DIVISION CONTROL PROTEIN 24 OB DOMAIN-CONTAINING PROTEIN-RELATED CELL DIVISION CONTROL PROTEIN 24 OB DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;single-stranded DNA binding#GO:0003697;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 LEPOC|Ensembl=ENSLOCG00000006235.1|UniProtKB=W5MGL8 W5MGL8 PTHR35819:SF1 PICALM INTERACTING MITOTIC REGULATOR PIMREG PROTEIN PIMREG LEPOC|Ensembl=ENSLOCG00000014137.1|UniProtKB=W5N9V4 W5N9V4 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017266.1|UniProtKB=W5NL47 W5NL47 PTHR19307:SF8 TUMOR PROTEIN D52 TUMOR PROTEIN D53 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000163.1|UniProtKB=W5LVM7 W5LVM7 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005515.1|UniProtKB=W5ME70 W5ME70 PTHR19375:SF379 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 LEPOC|Ensembl=ENSLOCG00000010227.1|UniProtKB=W5MVW3 W5MVW3 PTHR42693:SF5 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE D hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003526.1|UniProtKB=W5M710 W5M710 SPRING1 PTHR13481:SF0 SREBP REGULATING GENE PROTEIN SREBP REGULATING GENE PROTEIN LEPOC|Ensembl=ENSLOCG00000018231.1|UniProtKB=W5NNX3 W5NNX3 PTHR15258:SF3 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 3 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 LEPOC|Ensembl=ENSLOCG00000000330.1|UniProtKB=W5LW50 W5LW50 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000427.1|UniProtKB=W5LWG1 W5LWG1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014003.1|UniProtKB=W5N9F3 W5N9F3 PTHR23404:SF3 MOLYBDOPTERIN SYNTHASE RELATED MAP3K12-BINDING INHIBITORY PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010617.1|UniProtKB=W5MX93 W5MX93 PDCL3 PTHR45809:SF4 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 3 growth factor receptor binding#GO:0070851;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 positive regulation of gene expression#GO:0010628;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;vasculature development#GO:0001944;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;circulatory system development#GO:0072359;macromolecule biosynthetic process#GO:0009059;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;tube development#GO:0035295;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of cellular biosynthetic process#GO:0031326;angiogenesis#GO:0001525;regulation of macromolecule metabolic process#GO:0060255;protein folding#GO:0006457;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000000828.1|UniProtKB=W5LXR4 W5LXR4 PTHR13814:SF12 FETUIN KININOGEN-1 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of coagulation#GO:0050818;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of wound healing#GO:0061041;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of proteolysis#GO:0030162;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;negative regulation of coagulation#GO:0050819;negative regulation of response to stimulus#GO:0048585;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;regulation of response to stress#GO:0080134;regulation of body fluid levels#GO:0050878;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to wounding#GO:1903034;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of blood coagulation#GO:0030195;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>Bradykinin#P00438;Blood coagulation#P00011>Kininogen#P00451;Blood coagulation#P00011>HMWK#P00413 LEPOC|Ensembl=ENSLOCG00000009661.1|UniProtKB=W5MTU7 W5MTU7 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 LEPOC|Ensembl=ENSLOCG00000002792.1|UniProtKB=W5M4H5 W5M4H5 PTHR46320:SF1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015849.1|UniProtKB=W5NFV3 W5NFV3 PTHR21831:SF2 MICROTUBULE-ASSOCIATED PROTEIN 10 MICROTUBULE-ASSOCIATED PROTEIN 10 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;positive regulation of cell cycle#GO:0045787;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;spindle elongation#GO:0051231;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;positive regulation of cell cycle process#GO:0090068;supramolecular fiber organization#GO:0097435;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;cytoplasmic microtubule organization#GO:0031122;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;positive regulation of cell division#GO:0051781;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010141.1|UniProtKB=W5MVL8 W5MVL8 PTHR42693:SF9 ARYLSULFATASE FAMILY MEMBER STERYL-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012094.1|UniProtKB=W5N2M7 W5N2M7 PTHR23239:SF367 INTERMEDIATE FILAMENT KERATIN 15-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016439.1|UniProtKB=W5NI45 W5NI45 PTHR31226:SF1 TRANSMEMBRANE PROTEIN 117 TRANSMEMBRANE PROTEIN 117 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;regulation of cellular process#GO:0050794;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000015587.1|UniProtKB=W5NEY2 W5NEY2 PTHR24157:SF3 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006170.1|UniProtKB=W5MGE3 W5MGE3 PTHR24410:SF20 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006730.1|UniProtKB=W5MIB7 W5MIB7 UBE2E2 PTHR24068:SF70 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000009145.1|UniProtKB=W5MRZ2 W5MRZ2 PTHR45616:SF26 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8 LEPOC|Ensembl=ENSLOCG00000009119.1|UniProtKB=W5MRV9 W5MRV9 CLDN8 PTHR12002:SF24 CLAUDIN CLAUDIN-8 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000011715.1|UniProtKB=W5N190 W5N190 PTHR10903:SF180 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7-LIKE small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014165.1|UniProtKB=W5N9Z1 W5N9Z1 PTHR10602:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 Apoptosis signaling pathway#P00006>ELF2alpha#P00307 LEPOC|Ensembl=ENSLOCG00000007237.1|UniProtKB=W5MK54 W5MK54 PTHR24351:SF236 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C IOTA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015767.1|UniProtKB=W5NFK2 W5NFK2 PLXNC1 PTHR22625:SF4 PLEXIN PLEXIN-C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;regulation of GTPase activity#GO:0043087;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of nervous system development#GO:0051962;positive regulation of developmental process#GO:0051094;regulation of neuron projection development#GO:0010975;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of multicellular organismal process#GO:0051240 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005278.1|UniProtKB=W5MDA1 W5MDA1 PTHR45822:SF8 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to fatty acid#GO:0070542;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to fatty acid#GO:0071398;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003206.1|UniProtKB=W5M5Y2 W5M5Y2 SAMD12 PTHR20843:SF2 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 12 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012229.1|UniProtKB=W5N356 W5N356 PTHR11850:SF47 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;visual system development#GO:0150063;sensory system development#GO:0048880;pattern specification process#GO:0007389;positive regulation of biological process#GO:0048518;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000000823.1|UniProtKB=W5LXR1 W5LXR1 PTHR23055:SF20 CALCIUM BINDING PROTEINS RECOVERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Recoverin#P00756 LEPOC|Ensembl=ENSLOCG00000012746.1|UniProtKB=W5N4X6 W5N4X6 PTHR13608:SF3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016989.1|UniProtKB=W5NK42 W5NK42 PTHR45812:SF1 DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA polymerase complex#GO:0042575;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000015476.1|UniProtKB=W5NEI8 W5NEI8 PTHR24072:SF148 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOU GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052 small GTPase#PC00208 Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Axon guidance mediated by netrin#P00009>cdc42#P00364 LEPOC|Ensembl=ENSLOCG00000011540.1|UniProtKB=W5N0L8 W5N0L8 PTHR33690:SF2 DUF4605 DOMAIN-CONTAINING PROTEIN PROTEIN FAM241B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001888.1|UniProtKB=W5M1F8 W5M1F8 PTHR44303:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007443.1|UniProtKB=W5MKX0 W5MKX0 PTHR46241:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 2 LEPOC|Ensembl=ENSLOCG00000014715.1|UniProtKB=W5NBV4 W5NBV4 PTHR15151:SF13 PROTEIN EIGER ECTODYSPLASIN-A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009776.1|UniProtKB=W5MUA1 W5MUA1 PTHR13697:SF14 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, LIVER TYPE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate binding#GO:0030246;kinase activity#GO:0016301;cation binding#GO:0043169;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;monosaccharide binding#GO:0048029 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;small molecule catabolic process#GO:0044282;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;nucleoside diphosphate metabolic process#GO:0009132;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphofructokinase-1#P00672 LEPOC|Ensembl=ENSLOCG00000008096.1|UniProtKB=W5MN79 W5MN79 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;intracellular lipid transport#GO:0032365;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000548.1|UniProtKB=W5LWU8 W5LWU8 PTHR46711:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000010832.1|UniProtKB=W5MY18 W5MY18 PTHR23189:SF14 RNA RECOGNITION MOTIF-CONTAINING PARASPECKLE COMPONENT 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009451.1|UniProtKB=W5MT27 W5MT27 PTHR24023:SF903 COLLAGEN ALPHA COLLAGEN ALPHA-1(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000006901.1|UniProtKB=W5MIY6 W5MIY6 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000017761.1|UniProtKB=W5NMK6 W5NMK6 PTHR24070:SF290 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE, FAMILY 10, MEMBER A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000004909.1|UniProtKB=W5MBZ1 W5MBZ1 PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006001.1|UniProtKB=W5MFU4 W5MFU4 PTHR46573:SF1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009485.1|UniProtKB=W5MT81 W5MT81 PTHR13038:SF13 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9A cellular component assembly#GO:0022607;microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007515.1|UniProtKB=W5ML62 W5ML62 PTHR12125:SF12 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 6 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 carbohydrate derivative metabolic process#GO:1901135;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014322.1|UniProtKB=W5NAI4 W5NAI4 PTHR46006:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010981.1|UniProtKB=W5MYL5 W5MYL5 PTHR45632:SF9 LD33804P KELCH-LIKE PROTEIN 9 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;cullin family protein binding#GO:0097602;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of cell division#GO:0051302;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;protein metabolic process#GO:0019538;regulation of cytokinesis#GO:0032465;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011886.1|UniProtKB=W5N1V5 W5N1V5 PTHR33802:SF3 SI:CH211-161H7.5-RELATED SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000003677.1|UniProtKB=W5M7P2 W5M7P2 PTHR24416:SF88 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basal plasma membrane#GO:0009925;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 LEPOC|Ensembl=ENSLOCG00000011180.1|UniProtKB=W5MZD4 W5MZD4 PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 LEPOC|Ensembl=ENSLOCG00000009175.1|UniProtKB=W5MS33 W5MS33 HUNK PTHR24346:SF80 MAP/MICROTUBULE AFFINITY-REGULATING KINASE HORMONALLY UP-REGULATED NEU TUMOR-ASSOCIATED KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008177.1|UniProtKB=W5MNG7 W5MNG7 PTHR10971:SF5 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nucleoplasm#GO:0005654;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006692.1|UniProtKB=W5MI90 W5MI90 PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001891.1|UniProtKB=W5M1F7 W5M1F7 PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000002406.1|UniProtKB=W5M379 W5M379 PTHR12425:SF4 SYNEMBRYN SYNEMBRYN-A nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;binding#GO:0005488;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006629.1|UniProtKB=W5MHZ6 W5MHZ6 PTHR22961:SF14 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 3 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004357.1|UniProtKB=W5M9Z5 W5M9Z5 PTHR12665:SF13 ORMDL PROTEINS ORM1-LIKE PROTEIN 2 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;intracellular chemical homeostasis#GO:0055082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011155.1|UniProtKB=W5MZ97 W5MZ97 PTHR10639:SF1 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN A protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;postsynapse#GO:0098794;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Huntington disease#P00029>Clathrin#P00798 LEPOC|Ensembl=ENSLOCG00000007966.1|UniProtKB=W5MMR6 W5MMR6 PTHR15736:SF2 PROTEIN FAM131B-RELATED PROTEIN FAM131C LEPOC|Ensembl=ENSLOCG00000013176.1|UniProtKB=W5N6H0 W5N6H0 PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015322.1|UniProtKB=W5NDZ7 W5NDZ7 PTHR24418:SF92 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;adaptive immune response#GO:0002250;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Btk#P00400 LEPOC|Ensembl=ENSLOCG00000015743.1|UniProtKB=W5NFH1 W5NFH1 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000017998.1|UniProtKB=W5NN90 W5NN90 PTHR24034:SF207 EGF-LIKE DOMAIN-CONTAINING PROTEIN CD248 MOLECULE extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013680.1|UniProtKB=W5N8B1 W5N8B1 PTHR46102:SF1 AXIN AXIN-2 SMAD binding#GO:0046332;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;ubiquitin protein ligase binding#GO:0031625;beta-catenin binding#GO:0008013;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of protein modification process#GO:0031401;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of protein catabolic process#GO:0045732;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of cellular process#GO:0048523;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of chromosome organization#GO:0033044;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of cell cycle#GO:0051726;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of transferase activity#GO:0051338;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 LEPOC|Ensembl=ENSLOCG00000010862.1|UniProtKB=W5MY52 W5MY52 PTHR22807:SF34 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000007334.1|UniProtKB=W5MKH3 W5MKH3 PTHR11348:SF4 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 4 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000002288.1|UniProtKB=W5M2R9 W5M2R9 PTHR46104:SF1 GENE 9195-RELATED-RELATED GENE 9195-RELATED LEPOC|Ensembl=ENSLOCG00000005739.1|UniProtKB=W5MEX5 W5MEX5 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010434.1|UniProtKB=W5MWQ7 W5MWQ7 DNM1 PTHR11566:SF54 DYNAMIN DYNAMIN-3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;receptor internalization#GO:0031623;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of organelle localization#GO:0051656;vesicle-mediated transport in synapse#GO:0099003 supramolecular complex#GO:0099080;synapse#GO:0045202;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000437.1|UniProtKB=W5LWH6 W5LWH6 PTHR46890:SF29 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000008913.1|UniProtKB=W5MR42 W5MR42 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012566.1|UniProtKB=W5N4B1 W5N4B1 PTHR24073:SF366 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5C GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001726.1|UniProtKB=W5M0T4 W5M0T4 PTHR46212:SF10 PEFLIN PEFLIN vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;protein-containing complex organization#GO:0043933;COPII-coated vesicle budding#GO:0090114;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 LEPOC|Ensembl=ENSLOCG00000015015.1|UniProtKB=W5NCX6 W5NCX6 PTHR24340:SF38 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004855.1|UniProtKB=W5MBR8 W5MBR8 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015713.1|UniProtKB=W5NFD4 W5NFD4 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013478.1|UniProtKB=W5N7L2 W5N7L2 PTHR18881:SF2 POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1-RELATED POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;sperm flagellum#GO:0036126 LEPOC|Ensembl=ENSLOCG00000004277.1|UniProtKB=W5M9Q2 W5M9Q2 PTHR11639:SF142 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-B cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167;signaling receptor binding#GO:0005102 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;regulation of cell population proliferation#GO:0042127;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010036.1|UniProtKB=W5MV73 W5MV73 LRRC9 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000008243.1|UniProtKB=W5MNR1 W5MNR1 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008107.1|UniProtKB=W5MN89 W5MN89 PTHR24040:SF15 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN VITAMIN K-DEPENDENT PROTEIN S-LIKE LEPOC|Ensembl=ENSLOCG00000009047.1|UniProtKB=W5MRM6 W5MRM6 PTHR45623:SF7 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010968.1|UniProtKB=W5MYJ4 W5MYJ4 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR ODORANT RECEPTOR-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017390.1|UniProtKB=W5NLI6 W5NLI6 PTHR24232:SF90 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011380.1|UniProtKB=W5N034 W5N034 PTHR10877:SF47 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017368.1|UniProtKB=W5NLG4 W5NLG4 PTHR24247:SF183 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M3 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;regulation of system process#GO:0044057;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;regulation of muscle system process#GO:0090257;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000018154.1|UniProtKB=W5NNP6 W5NNP6 PTHR13952:SF6 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007944.1|UniProtKB=W5MMP5 W5MMP5 PTHR12341:SF7 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 LEPOC|Ensembl=ENSLOCG00000011059.1|UniProtKB=W5MYW4 W5MYW4 PTHR11848:SF243 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 6-A-LIKE molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000011980.1|UniProtKB=W5N271 W5N271 PTHR41693:SF1 HEME-BINDING PROTEIN 1 SI:CH211-243A20.3 LEPOC|Ensembl=ENSLOCG00000002359.1|UniProtKB=W5M308 W5M308 PTHR16127:SF12 TAXILIN ALPHA-TAXILIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007841.1|UniProtKB=W5MMC0 W5MMC0 PTHR11827:SF9 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;sodium ion homeostasis#GO:0055078;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;apical part of cell#GO:0045177 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002627.1|UniProtKB=W5M3Y9 W5M3Y9 PTHR19878:SF7 AUTOPHAGY PROTEIN 16-LIKE PROTEIN ATG16L2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;catabolic process#GO:0009056;autophagosome assembly#GO:0000045;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012966.1|UniProtKB=W5N5Q9 W5N5Q9 PTHR21245:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 47 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016162.1|UniProtKB=W5NH18 W5NH18 PTHR12268:SF26 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 UTROPHIN biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012400.1|UniProtKB=W5N3R8 W5N3R8 PTHR10663:SF334 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017296.1|UniProtKB=W5NL92 W5NL92 PTHR13759:SF9 TWINFILIN TWINFILIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785;actin filament binding#GO:0051015 cellular localization#GO:0051641;negative regulation of protein depolymerization#GO:1901880;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of protein-containing complex disassembly#GO:0043244;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of protein depolymerization#GO:1901879;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;regulation of cell projection organization#GO:0031344;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein polymerization#GO:0032272;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of plasma membrane bounded cell projection assembly#GO:0120032;macromolecule localization#GO:0033036;regulation of protein-containing complex assembly#GO:0043254;cellular component disassembly#GO:0022411;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;regulation of actin filament depolymerization#GO:0030834;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;regulation of cell projection assembly#GO:0060491;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000018220.1|UniProtKB=W5NNW2 W5NNW2 PTHR24365:SF17 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000004444.1|UniProtKB=W5MAA3 W5MAA3 PTHR16206:SF9 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007357.1|UniProtKB=W5MKK3 W5MKK3 PTHR12271:SF133 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE, MITOCHONDRIAL adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000013288.1|UniProtKB=W5N6W1 W5N6W1 PTHR24390:SF261 ZINC FINGER PROTEIN SI:CH211-284E13.5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010462.1|UniProtKB=W5MWR2 W5MWR2 PTHR38564:SF2 SI:CH73-250A16.5-RELATED WU:FC46H12 PRECURSOR LEPOC|Ensembl=ENSLOCG00000012775.1|UniProtKB=W5N530 W5N530 PTHR24223:SF176 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017533.1|UniProtKB=W5NLX9 W5NLX9 SMIM15 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000006082.1|UniProtKB=W5MG38 W5MG38 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009481.1|UniProtKB=W5MT69 W5MT69 PTHR45620:SF27 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cell communication#GO:0007154;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular monoatomic ion homeostasis#GO:0006873;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007246.1|UniProtKB=W5MK60 W5MK60 PTHR10845:SF245 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 16 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002182.1|UniProtKB=W5M2E2 W5M2E2 PTHR24115:SF1004 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF15 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018114.1|UniProtKB=W5NNK6 W5NNK6 PTHR11818:SF107 BETA/GAMMA CRYSTALLIN CRYGMX PROTEIN structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001706.1|UniProtKB=W5M0S7 W5M0S7 PTHR21646:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016091.1|UniProtKB=W5NGR4 W5NGR4 PTHR21501:SF3 PROTEIN FAM-161 PROTEIN FAM161A cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000007502.1|UniProtKB=W5ML47 W5ML47 GPR83 PTHR24241:SF181 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008577.1|UniProtKB=W5MPX3 W5MPX3 PTHR11576:SF24 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013596.1|UniProtKB=W5N815 W5N815 PTHR23140:SF5 RNA PROCESSING PROTEIN LD23810P U2-ASSOCIATED SR140 PROTEIN-LIKE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000001535.1|UniProtKB=W5M055 W5M055 PTHR13343:SF15 CREG1 PROTEIN PROTEIN CREG2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000009547.1|UniProtKB=W5MTH8 W5MTH8 PTHR13803:SF42 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24B cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000002714.1|UniProtKB=W5M480 W5M480 PTHR10250:SF19 MICROSOMAL GLUTATHIONE S-TRANSFERASE MICROSOMAL GLUTATHIONE S-TRANSFERASE 3B glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001247.1|UniProtKB=W5LZ63 W5LZ63 PTHR24208:SF96 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016462.1|UniProtKB=W5NI77 W5NI77 TIMP3 PTHR11844:SF22 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 3 peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000015061.1|UniProtKB=W5ND26 W5ND26 PTHR24070:SF200 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2C GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;small GTPase-mediated signal transduction#GO:0007264;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;negative regulation of cell migration#GO:0030336 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906 LEPOC|Ensembl=ENSLOCG00000009393.1|UniProtKB=W5MSU7 W5MSU7 PTHR44858:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 6 UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED LEPOC|Ensembl=ENSLOCG00000017579.1|UniProtKB=W5NM25 W5NM25 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR ODORANT RECEPTOR-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004511.1|UniProtKB=W5MAJ8 W5MAJ8 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004017.1|UniProtKB=W5M8U0 W5M8U0 PTHR46311:SF3 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 8 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016822.1|UniProtKB=W5NJI3 W5NJI3 PTHR32055:SF1 INTEGRIN BETA-1-BINDING PROTEIN 1 INTEGRIN BETA-1-BINDING PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;regulation of cell-matrix adhesion#GO:0001952;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cell junction assembly#GO:1901888;negative regulation of cellular component organization#GO:0051129;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of cell-substrate adhesion#GO:0010810;negative regulation of cell adhesion#GO:0007162 intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;lamellipodium#GO:0030027;ruffle#GO:0001726;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018319.1|UniProtKB=W5NP61 W5NP61 PTHR11984:SF12 CONNEXIN GAP JUNCTION ALPHA-3 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000000608.1|UniProtKB=W5LX13 W5LX13 CDYL2 PTHR43684:SF2 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN 2 transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002524.1|UniProtKB=W5M3K7 W5M3K7 PTHR46255:SF2 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017772.1|UniProtKB=W5NML7 W5NML7 PTHR24232:SF82 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 8-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017815.1|UniProtKB=W5NMR0 W5NMR0 PTHR23257:SF706 SERINE-THREONINE PROTEIN KINASE PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE MOS transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005905.1|UniProtKB=W5MFH5 W5MFH5 ARHGAP9 PTHR23176:SF103 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 9 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000011100.1|UniProtKB=W5MZ25 W5MZ25 PTHR46139:SF1 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006487.1|UniProtKB=W5MHH4 W5MHH4 PTHR12277:SF52 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;regulation of synapse structure or activity#GO:0050803;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of postsynapse organization#GO:0099175;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011307.1|UniProtKB=W5MZT3 W5MZT3 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000014199.1|UniProtKB=W5NA33 W5NA33 PTHR13843:SF6 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1A cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;actin binding#GO:0003779;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cell projection organization#GO:0030030;dendrite development#GO:0016358;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;anatomical structure morphogenesis#GO:0009653;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cytosol#GO:0005829;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cell body#GO:0044297;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000002409.1|UniProtKB=W5M367 W5M367 PTHR10334:SF589 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANCYLOSTOMA SECRETED PROTEIN ISOFORM X1-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004957.1|UniProtKB=W5MC55 W5MC55 PTHR11977:SF51 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011956.1|UniProtKB=W5N245 W5N245 DDX41 PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000005734.1|UniProtKB=W5MEW7 W5MEW7 PTHR21713:SF38 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NAC-A_B DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016619.1|UniProtKB=W5NIS0 W5NIS0 PTHR11915:SF429 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 muscle structure development#GO:0061061;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;Z disc#GO:0030018;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cortical actin cytoskeleton#GO:0030864;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cell projection#GO:0042995;cytoskeleton#GO:0005856;myofibril#GO:0030016;plasma membrane#GO:0005886;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000006228.1|UniProtKB=W5MGL0 W5MGL0 HAPSTR1 PTHR31624:SF4 UPF0472 PROTEIN C16ORF72 CHROMOSOME 16 OPEN READING FRAME 72 LEPOC|Ensembl=ENSLOCG00000011312.1|UniProtKB=W5MZU3 W5MZU3 PTHR23055:SF13 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 1 cation binding#GO:0043169;molecular function activator activity#GO:0140677;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;enzyme activator activity#GO:0008047;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cyclase activity#GO:0031279;positive regulation of cellular metabolic process#GO:0031325;system process#GO:0003008;positive regulation of molecular function#GO:0044093;visual perception#GO:0007601;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of biological process#GO:0048518;regulation of lyase activity#GO:0051339;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;nervous system process#GO:0050877;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of cyclase activity#GO:0031281;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular biosynthetic process#GO:0031326;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;positive regulation of lyase activity#GO:0051349;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;photoreceptor inner segment#GO:0001917;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000005141.1|UniProtKB=W5MCT1 W5MCT1 PTHR10913:SF16 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 3 protein-containing complex binding#GO:0044877;activin binding#GO:0048185;binding#GO:0005488 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000009771.1|UniProtKB=W5MU76 W5MU76 PTHR35449:SF1 PROTEIN SIX6OS1 PROTEIN SIX6OS1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;male gamete generation#GO:0048232;double-strand break repair#GO:0006302;homologous chromosome segregation#GO:0045143;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;DNA double-strand break processing#GO:0000729;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;cell differentiation#GO:0030154;DNA damage response#GO:0006974;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;germ cell development#GO:0007281;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;nuclear chromosome segregation#GO:0098813;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;oogenesis#GO:0048477;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;central element#GO:0000801;synaptonemal complex#GO:0000795 LEPOC|Ensembl=ENSLOCG00000018275.1|UniProtKB=W5NP17 W5NP17 PTHR19290:SF161 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BHLH TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002640.1|UniProtKB=W5M421 W5M421 PTHR22772:SF4 NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000013087.1|UniProtKB=W5N667 W5N667 PTHR10529:SF270 AP COMPLEX SUBUNIT MU AP-4 COMPLEX SUBUNIT MU-1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;lysosomal transport#GO:0007041;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010663.1|UniProtKB=W5MXF4 W5MXF4 PTHR43795:SF51 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED AMINOTRANSFERASE CLASS I_CLASSII DOMAIN-CONTAINING PROTEIN transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011305.1|UniProtKB=W5MZT0 W5MZT0 PTHR23055:SF11 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 2 cation binding#GO:0043169;molecular function activator activity#GO:0140677;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;enzyme activator activity#GO:0008047;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 regulation of lyase activity#GO:0051339;regulation of phosphate metabolic process#GO:0019220;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cyclase activity#GO:0031279;system process#GO:0003008;nervous system process#GO:0050877;visual perception#GO:0007601;regulation of catalytic activity#GO:0050790;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;photoreceptor inner segment#GO:0001917;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000007084.1|UniProtKB=W5MJL8 W5MJL8 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000014155.1|UniProtKB=W5N9X7 W5N9X7 PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010137.1|UniProtKB=W5MVJ9 W5MVJ9 PTHR45807:SF1 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK2 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;kinase activity#GO:0016301;cytokine receptor binding#GO:0005126;protein kinase activity#GO:0004672 signal transduction#GO:0007165;response to cytokine#GO:0034097;response to peptide hormone#GO:0043434;developmental process#GO:0032502;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor tyrosine protein kinase#PC00168 CCKR signaling map#P06959>JAK2#P07156;PI3 kinase pathway#P00048>JAK#P01176;Interferon-gamma signaling pathway#P00035>Jak2#P00952;PDGF signaling pathway#P00047>Jak#P01155;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846;JAK/STAT signaling pathway#P00038>Jak#P01034 LEPOC|Ensembl=ENSLOCG00000013481.1|UniProtKB=W5N7M0 W5N7M0 PTHR11036:SF69 SEMAPHORIN SEMA DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011243.1|UniProtKB=W5MZK6 W5MZK6 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010625.1|UniProtKB=W5MXA3 W5MXA3 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013088.1|UniProtKB=W5N665 W5N665 PTHR45869:SF7 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN LEPOC|Ensembl=ENSLOCG00000012440.1|UniProtKB=W5N3V2 W5N3V2 PTHR13286:SF6 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L-RELATED molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005210.1|UniProtKB=W5MD18 W5MD18 PTHR12537:SF1 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015145.1|UniProtKB=W5NDD5 W5NDD5 PTHR24174:SF3 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002229.1|UniProtKB=W5M2K4 W5M2K4 PTHR10290:SF24 DNA TOPOISOMERASE I DNA TOPOISOMERASE I catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cell cycle#GO:0007049;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA topoisomerase#PC00017 LEPOC|Ensembl=ENSLOCG00000003168.1|UniProtKB=W5M5T6 W5M5T6 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000002438.1|UniProtKB=W5M3A3 W5M3A3 PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008262.1|UniProtKB=W5MNT0 W5MNT0 PTHR48012:SF14 STERILE20-LIKE KINASE, ISOFORM B-RELATED STE20_SPS1-RELATED PROLINE-ALANINE-RICH PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of metal ion transport#GO:0010959;regulation of lymphocyte migration#GO:2000401;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of transport#GO:0051051;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;regulation of potassium ion transmembrane transport#GO:1901379;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;peptidyl-threonine phosphorylation#GO:0018107;biological regulation#GO:0065007;positive regulation of leukocyte chemotaxis#GO:0002690;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009545.1|UniProtKB=W5MTG6 W5MTG6 PTHR45620:SF12 PDF RECEPTOR-LIKE PROTEIN-RELATED PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PAC1-R#P06712;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06685;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06898 LEPOC|Ensembl=ENSLOCG00000004062.1|UniProtKB=W5M8Z3 W5M8Z3 PTHR11753:SF34 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX SUBUNIT SIGMA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000010779.1|UniProtKB=W5MXV1 W5MXV1 PTHR46538:SF2 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000010393.1|UniProtKB=W5MWI5 W5MWI5 NEK5 PTHR44899:SF1 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK5 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015489.1|UniProtKB=W5NEK3 W5NEK3 PTHR13326:SF31 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013210.1|UniProtKB=W5N6L6 W5N6L6 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003477.1|UniProtKB=W5M6W1 W5M6W1 NRIP3 PTHR12917:SF16 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 3 aspartic protease#PC00053;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017082.1|UniProtKB=W5NKF2 W5NKF2 MCHR2 PTHR24229:SF88 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2-RELATED neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012705.1|UniProtKB=W5N4S8 W5N4S8 PTHR13170:SF24 O-GLCNACASE O-GLCNACASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017526.1|UniProtKB=W5NLX2 W5NLX2 PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of coagulation#GO:0050818;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of wound healing#GO:0061041;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;regulation of body fluid levels#GO:0050878;cell communication#GO:0007154;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of response to wounding#GO:1903034;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-1#P00404;Angiogenesis#P00005>PAR#P00192 LEPOC|Ensembl=ENSLOCG00000012491.1|UniProtKB=W5N416 W5N416 PTHR35446:SF2 SI:CH211-175M2.5 CARBOXYMUCONOLACTONE DECARBOXYLASE-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014829.1|UniProtKB=W5NCA1 W5NCA1 PTHR23099:SF0 TRANSCRIPTIONAL REGULATOR GERM CELL NUCLEAR ACIDIC PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000014491.1|UniProtKB=W5NB23 W5NB23 PTHR10969:SF55 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GABA(A) RECEPTOR-ASSOCIATED PROTEIN binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000002302.1|UniProtKB=W5M2T0 W5M2T0 PTHR11995:SF14 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152 respirasome#GO:0070469;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;oxidoreductase complex#GO:1990204;respiratory chain complex I#GO:0045271;cellular anatomical entity#GO:0110165;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004983.1|UniProtKB=W5MC91 W5MC91 PTHR24027:SF424 CADHERIN-23 CADHERIN-16 ISOFORM X3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000017281.1|UniProtKB=W5NL66 W5NL66 LAMA2 PTHR10574:SF291 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000013363.1|UniProtKB=W5N768 W5N768 PTHR22572:SF15 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 LEPOC|Ensembl=ENSLOCG00000004538.1|UniProtKB=W5MAL9 W5MAL9 PTHR19957:SF212 SYNTAXIN T-SNARE DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012385.1|UniProtKB=W5N3P3 W5N3P3 KATNAL2 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000009407.1|UniProtKB=W5MSX1 W5MSX1 PTHR10562:SF126 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>Sumo-1 ligase#P04635 LEPOC|Ensembl=ENSLOCG00000014203.1|UniProtKB=W5NA49 W5NA49 PTHR12750:SF11 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016008.1|UniProtKB=W5NGF8 W5NGF8 PTHR13479:SF66 30S RIBOSOMAL PROTEIN S18 LARGE RIBOSOMAL SUBUNIT PROTEIN ML66 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000018270.1|UniProtKB=W5NP12 W5NP12 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000015463.1|UniProtKB=W5NEH2 W5NEH2 PTHR10606:SF15 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;sugar-phosphatase activity#GO:0050308;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002641.1|UniProtKB=W5M3Z8 W5M3Z8 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000008102.1|UniProtKB=W5MN83 W5MN83 PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL electron transfer activity#GO:0009055;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007824.1|UniProtKB=W5MM92 W5MM92 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045 LEPOC|Ensembl=ENSLOCG00000014150.1|UniProtKB=W5N9X2 W5N9X2 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008352.1|UniProtKB=W5MP40 W5MP40 PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006465.1|UniProtKB=W5MHF1 W5MHF1 PTHR15811:SF5 MTH938 DOMAIN-CONTAINING PROTEIN MTH938 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009780.1|UniProtKB=W5MUA2 W5MUA2 PTHR24361:SF838 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20 ISOFORM X1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001943.1|UniProtKB=W5M1J0 W5M1J0 PTHR24233:SF4 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 171 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016364.1|UniProtKB=W5NHU6 W5NHU6 PTHR10281:SF72 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUDESIN cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001183.1|UniProtKB=W5LYY6 W5LYY6 PTHR12080:SF80 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013888.1|UniProtKB=W5N916 W5N916 PTHR11818:SF15 BETA/GAMMA CRYSTALLIN BETAGAMMAX-CRYSTALLIN structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011322.1|UniProtKB=W5MZV1 W5MZV1 PTHR11101:SF83 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transport#GO:0015698 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011590.1|UniProtKB=W5N0T9 W5N0T9 PTHR24037:SF7 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 FLOCCULATION PROTEIN FLO11 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000011778.1|UniProtKB=W5N1H7 W5N1H7 PTHR46209:SF2 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-10 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002498.1|UniProtKB=W5M3H2 W5M3H2 PTHR32289:SF4 PROTEIN FAM167A PROTEIN FAM167B LEPOC|Ensembl=ENSLOCG00000011605.1|UniProtKB=W5N0V1 W5N0V1 PTHR46606:SF1 SHOOTIN-1 SHOOTIN-1 neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cell leading edge#GO:0031252;cytoplasm#GO:0005737;axonal growth cone#GO:0044295;neuron projection#GO:0043005;distal axon#GO:0150034;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014416.1|UniProtKB=W5NAT9 W5NAT9 PTHR14085:SF3 WD-REPEAT PROTEIN BING4 WD REPEAT-CONTAINING PROTEIN 46 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000010805.1|UniProtKB=W5MXX9 W5MXX9 PTHR13809:SF1 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-11 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 LEPOC|Ensembl=ENSLOCG00000007839.1|UniProtKB=W5MMB6 W5MMB6 PTHR11905:SF130 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 15 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017731.1|UniProtKB=W5NMH6 W5NMH6 PTHR18843:SF7 TORSIN-1A-INTERACTING PROTEIN LAMINA-ASSOCIATED POLYPEPTIDE 1B ISOFORM 1-RELATED cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005929.1|UniProtKB=W5MFP4 W5MFP4 PTHR11915:SF422 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016800.1|UniProtKB=W5NJF6 W5NJF6 CST7 PTHR47141:SF1 CYSTATIN-F CYSTATIN-F peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of gene expression#GO:0010629;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;negative regulation of inflammatory response#GO:0050728;regulation of system process#GO:0044057;negative regulation of defense response#GO:0031348;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of macrophage activation#GO:0043030;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of multicellular organismal process#GO:0051241;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;regulation of response to stress#GO:0080134;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of leukocyte activation#GO:0002694;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;negative regulation of macromolecule metabolic process#GO:0010605;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of immune system process#GO:0002683;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000015377.1|UniProtKB=W5NE65 W5NE65 PTHR48099:SF15 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 LEPOC|Ensembl=ENSLOCG00000008855.1|UniProtKB=W5MQW4 W5MQW4 PTHR12234:SF0 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMIDOYLTRANSFERASE-CYCLODEAMINASE LEPOC|Ensembl=ENSLOCG00000015901.1|UniProtKB=W5NG21 W5NG21 PTHR21661:SF70 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004838.1|UniProtKB=W5MBQ2 W5MBQ2 PTHR45617:SF162 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING 32 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012663.1|UniProtKB=W5N4M7 W5N4M7 PTHR45627:SF5 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005979.1|UniProtKB=W5MFR3 W5MFR3 PTHR46096:SF5 PERFORIN-1 PERFORIN 1.2 PRECURSOR-RELATED wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;cell recognition#GO:0008037;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;T cell mediated immunity#GO:0002456;cell killing#GO:0001906;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;defense response to symbiont#GO:0140546;cell-cell recognition#GO:0009988;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation#GO:0001775;leukocyte mediated cytotoxicity#GO:0001909;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;adaptive immune response#GO:0002250;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;multicellular organismal process#GO:0032501;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;leukocyte activation#GO:0045321 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003642.1|UniProtKB=W5M7G6 W5M7G6 PTHR15162:SF9 ASPARTOACYLASE ASPARTOACYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007721.1|UniProtKB=W5MLW6 W5MLW6 PTHR24412:SF162 KELCH PROTEIN KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010048.1|UniProtKB=W5MV84 W5MV84 PTHR12372:SF6 PECANEX PECANEX-LIKE PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000002091.1|UniProtKB=W5M251 W5M251 PTHR10574:SF270 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000006953.1|UniProtKB=W5MJ54 W5MJ54 PTHR23277:SF106 NECTIN-RELATED NECTIN-1 ISOFORM X1-RELATED cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003382.1|UniProtKB=W5M6J4 W5M6J4 PTHR18849:SF4 LEUCINE RICH REPEAT PROTEIN GENE 29133-RELATED LEPOC|Ensembl=ENSLOCG00000003074.1|UniProtKB=W5M5F3 W5M5F3 PTHR21687:SF5 PLASMALEMMA VESICLE-ASSOCIATED PROTEIN PLASMALEMMA VESICLE-ASSOCIATED PROTEIN blood circulation#GO:0008015;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;system process#GO:0003008;positive regulation of immune system process#GO:0002684;circulatory system process#GO:0003013;positive regulation of leukocyte migration#GO:0002687;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;regulation of leukocyte migration#GO:0002685;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000006696.1|UniProtKB=W5MI80 W5MI80 PTHR19300:SF47 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 6 UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;glycosylation#GO:0070085;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017180.1|UniProtKB=W5NKS4 W5NKS4 PTHR14272:SF4 SERTA DOMAIN-CONTAINING PROTEIN 4 SERTA DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005225.1|UniProtKB=W5MD33 W5MD33 PTHR16483:SF0 GASTROKINE 1 BRICHOS DOMAIN-CONTAINING PROTEIN 5 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012148.1|UniProtKB=W5N2T3 W5N2T3 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 60S RIBOSOMAL PROTEIN L17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013477.1|UniProtKB=W5N7L3 W5N7L3 SPHK1 PTHR12358:SF47 SPHINGOSINE KINASE SPHINGOSINE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;alcohol biosynthetic process#GO:0046165;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;sphingolipid biosynthetic process#GO:0030148;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;organic hydroxy compound metabolic process#GO:1901615;regulation of apoptotic process#GO:0042981;cellular response to endogenous stimulus#GO:0071495;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;membrane lipid biosynthetic process#GO:0046467;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;membrane lipid metabolic process#GO:0006643;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Angiogenesis#P00005>SPK#P00229;VEGF signaling pathway#P00056>SPK#P01404 LEPOC|Ensembl=ENSLOCG00000017630.1|UniProtKB=W5NM76 W5NM76 PTHR22750:SF13 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013189.1|UniProtKB=W5N6J1 W5N6J1 PTHR10337:SF12 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 4 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011042.1|UniProtKB=W5MYU8 W5MYU8 PTHR14058:SF10 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 3 amyloid-beta binding#GO:0001540;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 LEPOC|Ensembl=ENSLOCG00000008946.1|UniProtKB=W5MR91 W5MR91 PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 LEPOC|Ensembl=ENSLOCG00000005814.1|UniProtKB=W5MF68 W5MF68 PTHR46522:SF1 CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE INACTIVE CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000009127.1|UniProtKB=W5MRW9 W5MRW9 PTHR45618:SF19 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to stress#GO:0006950;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000557.1|UniProtKB=W5LWV8 W5LWV8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007136.1|UniProtKB=W5MJT0 W5MJT0 PTHR24111:SF4 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000009751.1|UniProtKB=W5MU51 W5MU51 PTHR24248:SF163 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H2 RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004598.1|UniProtKB=W5MAV2 W5MAV2 PTHR13372:SF4 GEMININ GEMININ negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cell cycle#GO:0045786;regulation of DNA metabolic process#GO:0051052;negative regulation of metabolic process#GO:0009892;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006939.1|UniProtKB=W5MJ36 W5MJ36 PTHR11461:SF159 SERINE PROTEASE INHIBITOR, SERPIN PLASMA PROTEASE C1 INHIBITOR peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000011831.1|UniProtKB=W5N1R8 W5N1R8 PTHR11254:SF441 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE HECT-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;molecular function regulator activity#GO:0098772;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;molecular function inhibitor activity#GO:0140678 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of dendrite development#GO:0050773;negative regulation of biological process#GO:0048519;regulation of sodium ion transport#GO:0002028;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;regulation of metal ion transport#GO:0010959;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of monoatomic cation transmembrane transport#GO:1904062;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;organic substance catabolic process#GO:1901575;regulation of transporter activity#GO:0032409;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of transport#GO:0051051;regulation of plasma membrane bounded cell projection organization#GO:0120035;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron projection development#GO:0010975;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;negative regulation of monoatomic ion transport#GO:0043271;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002701.1|UniProtKB=W5M482 W5M482 PTHR13808:SF34 CBP/P300-RELATED CREB-BINDING PROTEIN histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;N-acyltransferase activity#GO:0016410;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;chromatin DNA binding#GO:0031490;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694 histone modifying enzyme#PC00261 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Hedgehog signaling pathway#P00025>CBP#P00691;p53 pathway#P00059>CBP#P04623;Wnt signaling pathway#P00057>CBP#P01448;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Hypoxia response via HIF activation#P00030>P300#P00814;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Huntington disease#P00029>CBP#P00777;Gonadotropin-releasing hormone receptor pathway#P06664>CBP#P06755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000018207.1|UniProtKB=W5NNU9 W5NNU9 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009486.1|UniProtKB=W5MT78 W5MT78 PTHR46942:SF1 SIALIC ACID-BINDING IG-LIKE LECTIN 15 SIALIC ACID-BINDING IG-LIKE LECTIN 15 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of hemopoiesis#GO:1903706;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of bone resorption#GO:0045124;regulation of tissue remodeling#GO:0034103;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of immune system process#GO:0002682;regulation of actin filament-based process#GO:0032970;regulation of bone remodeling#GO:0046850 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002549.1|UniProtKB=W5M3P2 W5M3P2 SLC29A2 PTHR10332:SF8 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015037.1|UniProtKB=W5NCZ7 W5NCZ7 PTHR16015:SF0 TRANSMEMBRANE PROTEIN 51 TRANSMEMBRANE PROTEIN 51 LEPOC|Ensembl=ENSLOCG00000010006.1|UniProtKB=W5MV34 W5MV34 PTHR24050:SF24 PA14 DOMAIN-CONTAINING PROTEIN EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000016158.1|UniProtKB=W5NH03 W5NH03 PTHR46864:SF1 LAFORIN LAFORIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004844.1|UniProtKB=W5MBT4 W5MBT4 ITGA5 PTHR23220:SF3 INTEGRIN ALPHA INTEGRIN ALPHA-5 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;cell adhesion mediated by integrin#GO:0033627;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;cell-matrix adhesion#GO:0007160;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000006043.1|UniProtKB=W5MFZ1 W5MFZ1 PTHR12396:SF12 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;heterochromatin formation#GO:0031507;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;DNA methylation-dependent heterochromatin formation#GO:0006346;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008860.1|UniProtKB=W5MQX4 W5MQX4 PTHR11211:SF16 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013929.1|UniProtKB=W5N964 W5N964 PTHR10005:SF8 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;negative regulation of BMP signaling pathway#GO:0030514;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014613.1|UniProtKB=W5NBH3 W5NBH3 PTHR24120:SF8 GH07239P ANKYRIN REPEAT AND SOCS BOX PROTEIN 12 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000004635.1|UniProtKB=W5MAZ3 W5MAZ3 PTHR11849:SF313 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016881.1|UniProtKB=W5NJQ8 W5NJQ8 PTHR16299:SF2 CENTROSOMAL PROTEIN KIZUNA CENTROSOMAL PROTEIN KIZUNA LEPOC|Ensembl=ENSLOCG00000006729.1|UniProtKB=W5MIB5 W5MIB5 PTHR20859:SF86 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 LEPOC|Ensembl=ENSLOCG00000013287.1|UniProtKB=W5N6X4 W5N6X4 PTHR46961:SF17 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN AAA+ ATPASE DOMAIN-CONTAINING PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000010022.1|UniProtKB=W5MV50 W5MV50 CYTL1 PTHR15974:SF0 CYTOKINE-LIKE PROTEIN 1 CYTOKINE-LIKE PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000003924.1|UniProtKB=W5M8H6 W5M8H6 PTHR12901:SF9 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG B, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005221.1|UniProtKB=W5MD26 W5MD26 PTHR32178:SF8 FAM187 PROTEIN FAM187B immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005776.1|UniProtKB=W5MF12 W5MF12 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009716.1|UniProtKB=W5MU09 W5MU09 PTHR28004:SF2 ZGC:162816-RELATED D-SERINE DEHYDRATASE lyase activity#GO:0016829;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 LEPOC|Ensembl=ENSLOCG00000016944.1|UniProtKB=W5NJY7 W5NJY7 PTHR13675:SF0 LYR MOTIF-CONTAINING PROTEIN 2 LYR MOTIF-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007221.1|UniProtKB=W5MK33 W5MK33 PTHR10005:SF3 SKI ONCOGENE-RELATED SKI-LIKE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;negative regulation of BMP signaling pathway#GO:0030514;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Gonadotropin-releasing hormone receptor pathway#P06664>SKIL#P06858 LEPOC|Ensembl=ENSLOCG00000002390.1|UniProtKB=W5M341 W5M341 PTHR19854:SF1 TRANSDUCIN BETA-LIKE 3 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016729.1|UniProtKB=W5NJ63 W5NJ63 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 LEPOC|Ensembl=ENSLOCG00000006532.1|UniProtKB=W5MHN3 W5MHN3 PTHR10857:SF2 COPINE COPINE-1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000003546.1|UniProtKB=W5M766 W5M766 PTHR13392:SF14 ATAXIN 1 ATAXIN-1-LIKE negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003893.1|UniProtKB=W5M8D6 W5M8D6 PTHR24081:SF0 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018024.1|UniProtKB=W5NNB6 W5NNB6 PTHR10656:SF37 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 2 transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003727.1|UniProtKB=W5M7W7 W5M7W7 PTHR48249:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017211.1|UniProtKB=W5NKX0 W5NKX0 PTHR11278:SF0 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 small-subunit processome#GO:0032040;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;90S preribosome#GO:0030686 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005573.1|UniProtKB=W5MEC4 W5MEC4 PTHR10110:SF59 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009623.1|UniProtKB=W5MTP5 W5MTP5 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008729.1|UniProtKB=W5MQH0 W5MQH0 PTHR23253:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017864.1|UniProtKB=W5NMV8 W5NMV8 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017428.1|UniProtKB=W5NLM4 W5NLM4 PTHR12002:SF203 CLAUDIN CLAUDIN-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000003272.1|UniProtKB=W5M669 W5M669 PTHR23316:SF3 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-5 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;signal transduction#GO:0007165;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;synaptic signaling#GO:0099536;protein localization to organelle#GO:0033365;cell-cell signaling#GO:0007267;signaling#GO:0023052;nuclear transport#GO:0051169;cellular response to stimulus#GO:0051716;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009739.1|UniProtKB=W5MU39 W5MU39 PTHR46024:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB2 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of biosynthetic process#GO:0009889;regulation of chromatin organization#GO:1902275;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;negative regulation of biosynthetic process#GO:0009890;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;heterochromatin organization#GO:0070828;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000002808.1|UniProtKB=W5M4J5 W5M4J5 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 LEPOC|Ensembl=ENSLOCG00000003770.1|UniProtKB=W5M7Y7 W5M7Y7 SBSPON PTHR20920:SF2 RPE-SPONDIN SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011931.1|UniProtKB=W5N212 W5N212 PTHR33861:SF3 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC positive regulation of gene expression#GO:0010628;male gamete generation#GO:0048232;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;male meiotic nuclear division#GO:0007140;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;cellular process involved in reproduction in multicellular organism#GO:0022412;cell cycle process#GO:0022402;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;meiotic cell cycle process#GO:1903046;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;multicellular organism reproduction#GO:0032504;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;meiotic nuclear division#GO:0140013;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015765.1|UniProtKB=W5NFJ9 W5NFJ9 PTHR23170:SF2 NY-REN-58 ANTIGEN CENTROSOMAL PROTEIN OF 83 KDA cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;organelle localization#GO:0051640;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;centrosome localization#GO:0051642;establishment of localization in cell#GO:0051649;plasma membrane bounded cell projection assembly#GO:0120031;establishment of organelle localization#GO:0051656 microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ciliary transition fiber#GO:0097539;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000012866.1|UniProtKB=W5N5D2 W5N5D2 PTHR48071:SF4 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN-RELATED LEPOC|Ensembl=ENSLOCG00000010115.1|UniProtKB=W5MVH8 W5MVH8 PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 LEPOC|Ensembl=ENSLOCG00000010274.1|UniProtKB=W5MW46 W5MW46 GK3P PTHR10196:SF69 SUGAR KINASE GLYCEROL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 LEPOC|Ensembl=ENSLOCG00000001062.1|UniProtKB=W5LYI9 W5LYI9 PTHR15186:SF9 RE48077P BCL-2_ADENOVIRUS E1B 19KD INTERACTION PROTEIN XR response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;apoptotic process#GO:0006915;cell death#GO:0008219;mitochondrion organization#GO:0007005;defense response to virus#GO:0051607;defense response#GO:0006952;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000011907.1|UniProtKB=W5N1Y1 W5N1Y1 PTHR12297:SF18 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2A cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011356.1|UniProtKB=W5N003 W5N003 PTHR24347:SF116 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006520.1|UniProtKB=W5MHM1 W5MHM1 PTHR21152:SF40 AMINOTRANSFERASE CLASS V ALANINE--GLYOXYLATE AMINOTRANSFERASE transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157 LEPOC|Ensembl=ENSLOCG00000013551.1|UniProtKB=W5N7V3 W5N7V3 PTHR11616:SF141 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;xenobiotic transmembrane transporter activity#GO:0042910;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003656.1|UniProtKB=W5M7J0 W5M7J0 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018277.1|UniProtKB=W5NP19 W5NP19 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000017323.1|UniProtKB=W5NLB9 W5NLB9 PTHR22923:SF118 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005825.1|UniProtKB=W5MF84 W5MF84 PTHR15346:SF0 DYNACTIN SUBUNIT DYNACTIN SUBUNIT 2 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017538.1|UniProtKB=W5NLY4 W5NLY4 GCNT1 PTHR19297:SF96 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008583.1|UniProtKB=W5MPY0 W5MPY0 PTHR11267:SF88 T-BOX PROTEIN-RELATED T-BOX BRAIN PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;central nervous system neuron differentiation#GO:0021953;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cell fate specification#GO:0001708;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of neuron projection development#GO:0010975;regulation of primary metabolic process#GO:0080090;forebrain development#GO:0030900;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000003894.1|UniProtKB=W5M8E1 W5M8E1 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000006880.1|UniProtKB=W5MIW0 W5MIW0 PTHR23411:SF41 TAPASIN IG KAPPA-B4 CHAIN C REGION immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013252.1|UniProtKB=W5N6S4 W5N6S4 PTHR12000:SF23 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012658.1|UniProtKB=W5N4M0 W5N4M0 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004733.1|UniProtKB=W5MBE0 W5MBE0 PTHR24103:SF673 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001219.1|UniProtKB=W5LZ64 W5LZ64 PTHR13102:SF0 NUCLEOLAR PROTEIN 9 NUCLEOLAR PROTEIN 9 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;ribosomal subunit export from nucleus#GO:0000054;organelle localization#GO:0051640;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;transport#GO:0006810;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nuclear export#GO:0051168;rRNA metabolic process#GO:0016072;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex localization#GO:0031503 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015409.1|UniProtKB=W5NEA7 W5NEA7 PTHR14221:SF0 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 LEPOC|Ensembl=ENSLOCG00000002232.1|UniProtKB=W5M2K8 W5M2K8 PTHR16592:SF8 ASTROTACTIN-1-LIKE ASTROTACTIN-1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;cell differentiation#GO:0030154;neuron migration#GO:0001764;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009636.1|UniProtKB=W5MTR8 W5MTR8 PTHR11207:SF5 RIBONUCLEASE III LARGE RIBOSOMAL SUBUNIT PROTEIN ML44 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;RNA nuclease activity#GO:0004540;double-stranded RNA binding#GO:0003725;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;primary miRNA processing#GO:0031053;amide biosynthetic process#GO:0043604;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;endoribonuclease complex#GO:1902555;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;nuclear protein-containing complex#GO:0140513;mitochondrial protein-containing complex#GO:0098798 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005437.1|UniProtKB=W5MDU3 W5MDU3 PTHR12461:SF105 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009272.1|UniProtKB=W5MSG4 W5MSG4 PTHR16798:SF0 FANCONI ANEMIA GROUP C PROTEIN FANCC FANCONI ANEMIA GROUP C PROTEIN DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;response to oxidative stress#GO:0006979;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006624.1|UniProtKB=W5MI07 W5MI07 PTHR23108:SF0 METHYLTRANSFERASE-RELATED METHYLTRANSFERASE-LIKE PROTEIN 22 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003475.1|UniProtKB=W5M6W3 W5M6W3 PTHR11567:SF180 ACID PHOSPHATASE-RELATED LYSOSOMAL ACID PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;lytic vacuole organization#GO:0080171;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009172.1|UniProtKB=W5MS28 W5MS28 PTHR13547:SF1 FAMILY NOT NAMED MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000005207.1|UniProtKB=W5MD10 W5MD10 SRMS PTHR24418:SF23 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRMS protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000013195.1|UniProtKB=W5N6K8 W5N6K8 SCN4A PTHR10037:SF223 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 4 SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000003156.1|UniProtKB=W5M5R8 W5M5R8 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010876.1|UniProtKB=W5MY68 W5MY68 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017474.1|UniProtKB=W5NLS0 W5NLS0 PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B LEPOC|Ensembl=ENSLOCG00000015244.1|UniProtKB=W5NDP8 W5NDP8 PTHR33721:SF1 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255A LEPOC|Ensembl=ENSLOCG00000007767.1|UniProtKB=W5MM24 W5MM24 PTHR45779:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP11 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005118.1|UniProtKB=W5MCS9 W5MCS9 PTHR44140:SF3 LD25575P DNAJ HOMOLOG SUBFAMILY C MEMBER 3 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017951.1|UniProtKB=W5NN45 W5NN45 PTHR20937:SF6 IP14615P MESODERM POSTERIOR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;mesoderm formation#GO:0001707;epithelium development#GO:0060429;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;gastrulation#GO:0007369;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;mesoderm development#GO:0007498;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011959.1|UniProtKB=W5N246 W5N246 EMB PTHR10075:SF4 BASIGIN RELATED EMBIGIN cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012342.1|UniProtKB=W5N3I7 W5N3I7 PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010530.1|UniProtKB=W5MX00 W5MX00 PTHR13778:SF3 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010471.1|UniProtKB=W5MWS8 W5MWS8 PTHR13296:SF0 BCAS2 PROTEIN PRE-MRNA-SPLICING FACTOR SPF27 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001682.1|UniProtKB=W5M0P3 W5M0P3 PTHR15600:SF42 SACSIN SACSIN heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 LEPOC|Ensembl=ENSLOCG00000015312.1|UniProtKB=W5NDY4 W5NDY4 PTHR19443:SF4 HEXOKINASE HEXOKINASE-2 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;intracellular chemical homeostasis#GO:0055082;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;organophosphate catabolic process#GO:0046434;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate phosphorylation#GO:0046835;organonitrogen compound metabolic process#GO:1901564;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;intracellular glucose homeostasis#GO:0001678;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 LEPOC|Ensembl=ENSLOCG00000005135.1|UniProtKB=W5MCS3 W5MCS3 PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012004.1|UniProtKB=W5N2B2 W5N2B2 PTHR13844:SF2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000012095.1|UniProtKB=W5N2Q2 W5N2Q2 PTHR11039:SF39 NEBULIN NEBULIN-RELATED-ANCHORING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;I band#GO:0031674 LEPOC|Ensembl=ENSLOCG00000011842.1|UniProtKB=W5N1R1 W5N1R1 PTHR45804:SF3 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-A13 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000015708.1|UniProtKB=W5NFC8 W5NFC8 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003895.1|UniProtKB=W5M8D9 W5M8D9 PTHR16516:SF5 AGAP007109-PA ZINC FINGER PROTEIN 488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;multicellular organism development#GO:0007275;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;oligodendrocyte differentiation#GO:0048709;regulation of RNA metabolic process#GO:0051252;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012529.1|UniProtKB=W5N481 W5N481 PTHR13389:SF0 PUMILIO HOMOLOG 3 PUMILIO HOMOLOG 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004446.1|UniProtKB=W5MAD9 W5MAD9 NOS3 PTHR19384:SF66 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor#GO:0016653;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;system process#GO:0003008;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;alpha-amino acid metabolic process#GO:1901605;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;response to molecule of bacterial origin#GO:0002237;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;regulation of lyase activity#GO:0051339;response to oxygen-containing compound#GO:1901700;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;circulatory system process#GO:0003013;organic acid metabolic process#GO:0006082;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;blood circulation#GO:0008015;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;response to lipid#GO:0033993;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;amino acid catabolic process#GO:0009063;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;L-amino acid metabolic process#GO:0170033;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;proteinogenic amino acid metabolic process#GO:0170039;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;arginine metabolic process#GO:0006525;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of blood pressure#GO:0008217;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of lyase activity#GO:0051349;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 oxidoreductase#PC00176 VEGF signaling pathway#P00056>eNOS#P01422;PI3 kinase pathway#P00048>NOS#P01205;Endothelin signaling pathway#P00019>eNOS#P00578;Interleukin signaling pathway#P00036>eNOS#P00986;Angiogenesis#P00005>eNOS#P00210 LEPOC|Ensembl=ENSLOCG00000010634.1|UniProtKB=W5MXB5 W5MXB5 PTHR19918:SF35 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG ISOFORM X1 protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016731.1|UniProtKB=W5NJ64 W5NJ64 PTHR15926:SF1 ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR LEPOC|Ensembl=ENSLOCG00000005109.1|UniProtKB=W5MCP1 W5MCP1 PTHR23192:SF29 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015710.1|UniProtKB=W5NFD0 W5NFD0 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000002157.1|UniProtKB=W5M2A5 W5M2A5 PTHR15193:SF2 CD83 ANTIGEN SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000013421.1|UniProtKB=W5N7D8 W5N7D8 PTHR23268:SF102 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002845.1|UniProtKB=W5M4P5 W5M4P5 PTHR11728:SF46 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;glycerol-3-phosphate metabolic process#GO:0006072;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012101.1|UniProtKB=W5N2N1 W5N2N1 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000005483.1|UniProtKB=W5ME06 W5ME06 PTHR24327:SF35 HOMEOBOX PROTEIN BRAIN-SPECIFIC HOMEOBOX PROTEIN HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009727.1|UniProtKB=W5MU17 W5MU17 NOVA1 PTHR10288:SF229 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000979.1|UniProtKB=W5LY95 W5LY95 PTHR10269:SF2 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005293.1|UniProtKB=W5MDD1 W5MDD1 PTHR45725:SF3 FORMIN HOMOLOGY 2 FAMILY MEMBER DELPHILIN LEPOC|Ensembl=ENSLOCG00000003332.1|UniProtKB=W5M6D6 W5M6D6 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000016572.1|UniProtKB=W5NIL0 W5NIL0 PTHR15344:SF3 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;small GTPase-mediated signal transduction#GO:0007264;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of anatomical structure size#GO:0090066;cellular response to stimulus#GO:0051716;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007715.1|UniProtKB=W5MLW1 W5MLW1 CLPB PTHR11638:SF93 ATP-DEPENDENT CLP PROTEASE MITOCHONDRIAL DISAGGREGASE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011748.1|UniProtKB=W5N1D6 W5N1D6 PTHR43675:SF9 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 oxoacid metabolic process#GO:0043436;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;secondary metabolic process#GO:0019748;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015747.1|UniProtKB=W5NFH6 W5NFH6 THUMPD2 PTHR14911:SF1 THUMP DOMAIN-CONTAINING THUMP DOMAIN-CONTAINING PROTEIN 2 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000017450.1|UniProtKB=W5NLP6 W5NLP6 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007410.1|UniProtKB=W5MKT8 W5MKT8 PTHR23092:SF51 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4B adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005122.1|UniProtKB=W5MCQ7 W5MCQ7 PTHR10513:SF24 DEOXYNUCLEOSIDE KINASE THYMIDINE KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000013047.1|UniProtKB=W5N609 W5N609 PTHR14511:SF15 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER C protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010837.1|UniProtKB=W5MY24 W5MY24 PTHR24248:SF139 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1A) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic cyclic compound#GO:0014070;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;dopamine receptor signaling pathway#GO:0007212;regulation of signal transduction#GO:0009966;cellular response to organic cyclic compound#GO:0071407;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 LEPOC|Ensembl=ENSLOCG00000007613.1|UniProtKB=W5MLI5 W5MLI5 PTHR23317:SF65 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000017719.1|UniProtKB=W5NMG5 W5NMG5 PTHR23268:SF117 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 29-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006601.1|UniProtKB=W5MHW8 W5MHW8 PTHR24099:SF4 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of cell division#GO:0051302;regulation of mitotic spindle organization#GO:0060236;regulation of cell cycle process#GO:0010564 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012890.1|UniProtKB=W5N5F9 W5N5F9 PTHR10024:SF234 SYNAPTOTAGMIN SYNAPTOTAGMIN-15-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000015194.1|UniProtKB=W5NDJ2 W5NDJ2 PTHR11101:SF46 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transport#GO:0015698 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017433.1|UniProtKB=W5NLM9 W5NLM9 PTHR12002:SF192 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000002913.1|UniProtKB=W5M4W3 W5M4W3 PTHR10105:SF4 SELENOPROTEIN P SELENOPROTEIN P2 small molecule binding#GO:0036094;binding#GO:0005488 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000004322.1|UniProtKB=W5M9X1 W5M9X1 PTHR23113:SF224 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Integrin signalling pathway#P00034>C3G#P00929 LEPOC|Ensembl=ENSLOCG00000013916.1|UniProtKB=W5N943 W5N943 PTHR36688:SF1 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014270.1|UniProtKB=W5NAA6 W5NAA6 PTHR15917:SF3 FAMILY NOT NAMED INHIBITORY SYNAPTIC FACTOR 1 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of postsynaptic membrane potential#GO:0060078;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279 LEPOC|Ensembl=ENSLOCG00000014493.1|UniProtKB=W5NB29 W5NB29 PTHR20937:SF6 IP14615P MESODERM POSTERIOR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;mesoderm formation#GO:0001707;epithelium development#GO:0060429;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;gastrulation#GO:0007369;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;mesoderm development#GO:0007498;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009837.1|UniProtKB=W5MUG3 W5MUG3 PTHR12112:SF49 BNIP - RELATED DHHA2 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;exopolyphosphatase activity#GO:0004309;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009905.1|UniProtKB=W5MUQ4 W5MUQ4 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014870.1|UniProtKB=W5NCF6 W5NCF6 PTHR23050:SF427 CALCIUM BINDING PROTEIN CALMODULIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of metal ion transport#GO:0010959;regulation of sequestering of calcium ion#GO:0051282;positive regulation of molecular function#GO:0044093;positive regulation of transport#GO:0051050;positive regulation of cation channel activity#GO:2001259;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of transporter activity#GO:0032411;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 LEPOC|Ensembl=ENSLOCG00000011881.1|UniProtKB=W5N1U6 W5N1U6 PTHR33802:SF4 SI:CH211-161H7.5-RELATED SI:DKEY-29D8.3 LEPOC|Ensembl=ENSLOCG00000000972.1|UniProtKB=W5LY84 W5LY84 PTHR45632:SF18 LD33804P KELCH-LIKE FAMILY MEMBER 43 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001596.1|UniProtKB=W5M0C6 W5M0C6 PTHR10201:SF298 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-28 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000001453.1|UniProtKB=W5LZV2 W5LZV2 PTHR24413:SF229 SPECKLE-TYPE POZ PROTEIN RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;regulation of protein metabolic process#GO:0051246;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001818.1|UniProtKB=W5M146 W5M146 PTHR10739:SF20 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE B cation binding#GO:0043169;transferase activity#GO:0016740;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006073.1|UniProtKB=W5MG26 W5MG26 PTHR12947:SF7 AMSH-LIKE PROTEASE AMSH-LIKE PROTEASE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein K63-linked deubiquitination#GO:0070536;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002038.1|UniProtKB=W5M1V5 W5M1V5 LIMD1 PTHR24219:SF3 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to abiotic stimulus#GO:0009628;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;response to oxygen levels#GO:0070482;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;negative regulation of signaling#GO:0023057;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 supramolecular complex#GO:0099080;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011272.1|UniProtKB=W5MZP9 W5MZP9 TOGARAM1 PTHR21567:SF87 CLASP CRESCERIN-LIKE PROTEIN CHE-12 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000532.1|UniProtKB=W5LWT1 W5LWT1 PTHR46890:SF29 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000003312.1|UniProtKB=W5M6A6 W5M6A6 PTHR28656:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 LEPOC|Ensembl=ENSLOCG00000009085.1|UniProtKB=W5MRT7 W5MRT7 PTHR46026:SF3 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 7 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;cellular component organization#GO:0016043;plasma membrane bounded cell projection assembly#GO:0120031;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cell leading edge#GO:0031252;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005187.1|UniProtKB=W5MCY3 W5MCY3 PTHR14167:SF52 SH3 DOMAIN-CONTAINING ENDOPHILIN-B1 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017154.1|UniProtKB=W5NKQ3 W5NKQ3 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014439.1|UniProtKB=W5NAW3 W5NAW3 PTHR23039:SF2 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 2 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000008891.1|UniProtKB=W5MR11 W5MR11 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000005060.1|UniProtKB=W5MCI3 W5MCI3 PTHR12002:SF115 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000009858.1|UniProtKB=W5MUJ4 W5MUJ4 PTHR22957:SF686 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GROWTH HORMONE-REGULATED TBC PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009843.1|UniProtKB=W5MUH7 W5MUH7 PTHR20837:SF7 CENTROSOMAL PROTEIN-RELATED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000002921.1|UniProtKB=W5M4Y5 W5M4Y5 PTHR23239:SF354 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006715.1|UniProtKB=W5MIA3 W5MIA3 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031;mRNA capping factor#PC00145 LEPOC|Ensembl=ENSLOCG00000015100.1|UniProtKB=W5ND76 W5ND76 PTHR14336:SF5 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 2 LEPOC|Ensembl=ENSLOCG00000016438.1|UniProtKB=W5NI44 W5NI44 PTHR46107:SF1 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 4 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000001860.1|UniProtKB=W5M1B4 W5M1B4 PTHR10454:SF157 CASPASE CASPASE-9 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Caspase 9#P00298;FAS signaling pathway#P00020>Caspase9#P00593;FAS signaling pathway#P00020>Pro-Caspase9#P00603;VEGF signaling pathway#P00056>Caspase9#P01410;Angiogenesis#P00005>Caspase 9#P00216;PI3 kinase pathway#P00048>Caspase-9#P01197 LEPOC|Ensembl=ENSLOCG00000016908.1|UniProtKB=W5NJU5 W5NJU5 PTHR24301:SF2 THROMBOXANE-A SYNTHASE THROMBOXANE-A SYNTHASE isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001666.1|UniProtKB=W5M0M0 W5M0M0 PTHR12875:SF0 GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG localization within membrane#GO:0051668;protein insertion into ER membrane#GO:0045048;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005518.1|UniProtKB=W5ME53 W5ME53 PTHR10704:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;amino sugar metabolic process#GO:0006040;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014814.1|UniProtKB=W5NC82 W5NC82 PTHR32193:SF5 REGULATOR OF CELL CYCLE RGCC RGCC PROTEIN LEPOC|Ensembl=ENSLOCG00000017185.1|UniProtKB=W5NKT1 W5NKT1 PTHR14196:SF5 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008126.1|UniProtKB=W5MNA7 W5MNA7 PTHR47980:SF17 LD44762P RAS-RELATED PROTEIN RAB-3D GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005035.1|UniProtKB=W5MCF6 W5MCF6 PTHR10044:SF163 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of apoptotic process#GO:0042981;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein modification process#GO:0031401;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000012418.1|UniProtKB=W5N3T0 W5N3T0 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007682.1|UniProtKB=W5MLR9 W5MLR9 PTHR24070:SF428 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB-LIKE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000018241.1|UniProtKB=W5NNY3 W5NNY3 PTHR24235:SF21 NEUROPEPTIDE Y RECEPTOR PROLACTIN RELEASING HORMONE RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005446.1|UniProtKB=W5MDW6 W5MDW6 PTHR45616:SF59 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8 structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;skin development#GO:0043588;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;epidermis development#GO:0008544;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;intermediate filament organization#GO:0045109;multicellular organismal process#GO:0032501;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;extracellular region#GO:0005576;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;extracellular space#GO:0005615;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;keratin filament#GO:0045095;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000011925.1|UniProtKB=W5N1Z8 W5N1Z8 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016647.1|UniProtKB=W5NIV5 W5NIV5 PTHR12027:SF87 WNT RELATED PROTEIN WNT-5B molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000010013.1|UniProtKB=W5MV37 W5MV37 PTHR16083:SF9 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PML body#GO:0016605 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004913.1|UniProtKB=W5MC02 W5MC02 PTHR11062:SF8 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 1 acetylglucosaminyltransferase activity#GO:0008375;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008132.1|UniProtKB=W5MNC7 W5MNC7 PTHR11730:SF42 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE B inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012854.1|UniProtKB=W5N5B5 W5N5B5 PTHR45832:SF3 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000000616.1|UniProtKB=W5M8W8 W5M8W8 C9orf78 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER SPLICING FACTOR C9ORF78 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011225.1|UniProtKB=W5MZJ6 W5MZJ6 TLL2 PTHR10127:SF866 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;dorsal/ventral pattern formation#GO:0009953;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;proteolysis#GO:0006508;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000007062.1|UniProtKB=W5MJJ0 W5MJJ0 PTHR28562:SF1 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of metabolic process#GO:0019222 LEPOC|Ensembl=ENSLOCG00000011978.1|UniProtKB=W5N277 W5N277 PTHR32083:SF0 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017554.1|UniProtKB=W5NM00 W5NM00 PTHR48153:SF3 UFM1-SPECIFIC PROTEASE 2 INACTIVE UFM1-SPECIFIC PROTEASE 1 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000017650.1|UniProtKB=W5NM96 W5NM96 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011215.1|UniProtKB=W5MZH9 W5MZH9 PTHR18864:SF1 KINECTIN KINECTIN LEPOC|Ensembl=ENSLOCG00000017118.1|UniProtKB=W5NKJ2 W5NKJ2 PTHR24343:SF567 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE BRSK2 ISOFORM X1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015563.1|UniProtKB=W5NEU6 W5NEU6 PTHR11949:SF10 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000007714.1|UniProtKB=W5MLV8 W5MLV8 PTHR13153:SF5 CGTHBA PROTEIN -14 GENE PROTEIN GATOR COMPLEX PROTEIN NPRL3 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;regulation of autophagy#GO:0010506;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;negative regulation of TORC1 signaling#GO:1904262;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859 LEPOC|Ensembl=ENSLOCG00000012064.1|UniProtKB=W5N2I7 W5N2I7 PTHR23073:SF31 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B ATP-dependent activity#GO:0140657 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound catabolic process#GO:1901565;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of protein-containing complex assembly#GO:0043254;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular component biogenesis#GO:0044089;protein metabolic process#GO:0019538;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000017177.1|UniProtKB=W5NKS1 W5NKS1 PTHR11003:SF329 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 17-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012662.1|UniProtKB=W5N4M5 W5N4M5 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008387.1|UniProtKB=W5MP78 W5MP78 PTHR19331:SF487 SCAVENGER RECEPTOR DOMAIN-CONTAINING SOLUBLE SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SSC5D serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005998.1|UniProtKB=W5MFU2 W5MFU2 PTHR15135:SF2 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 3 regulation of metal ion transport#GO:0010959;system process#GO:0003008;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;skeletal muscle contraction#GO:0003009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of protein localization to membrane#GO:1905475;regulation of calcium ion transport#GO:0051924;positive regulation of transport#GO:0051050;nervous system process#GO:0050877;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;positive regulation of cellular process#GO:0048522;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of protein localization#GO:1903829;muscle system process#GO:0003012;muscle contraction#GO:0006936 LEPOC|Ensembl=ENSLOCG00000005209.1|UniProtKB=W5MD21 W5MD21 PTHR10625:SF42 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 7 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CCKR signaling map#P06959>HDAC7#P07235 LEPOC|Ensembl=ENSLOCG00000007864.1|UniProtKB=W5MMD6 W5MMD6 PTHR10358:SF21 ENDOSULFINE ALPHA-ENDOSULFINE phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;molecular function inhibitor activity#GO:0140678;protein phosphatase inhibitor activity#GO:0004864;enzyme regulator activity#GO:0030234 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of phosphorus metabolic process#GO:0010563;regulation of dephosphorylation#GO:0035303;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005363.1|UniProtKB=W5MDK3 W5MDK3 PTHR11477:SF3 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000006119.1|UniProtKB=W5MG86 W5MG86 PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013813.1|UniProtKB=W5N8S6 W5N8S6 CHRDL1 PTHR46303:SF2 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003789.1|UniProtKB=W5M817 W5M817 PTHR12246:SF13 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE ZDHHC16 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009897.1|UniProtKB=W5MUQ1 W5MUQ1 PTHR13817:SF88 TITIN CONTACTIN-3 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011737.1|UniProtKB=W5N1C0 W5N1C0 NEBL PTHR11039:SF48 NEBULIN NEBULETTE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;I band#GO:0031674 LEPOC|Ensembl=ENSLOCG00000008017.1|UniProtKB=W5MMX7 W5MMX7 LDAF1 PTHR14275:SF0 PROMETHIN LIPID DROPLET ASSEMBLY FACTOR 1 LEPOC|Ensembl=ENSLOCG00000017791.1|UniProtKB=W5NMN6 W5NMN6 PTHR12002:SF84 CLAUDIN CLAUDIN-22 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000003507.1|UniProtKB=W5M6Z4 W5M6Z4 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001553.1|UniProtKB=W5M083 W5M083 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000012024.1|UniProtKB=W5N2D0 W5N2D0 PTHR14523:SF1 UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN LEPOC|Ensembl=ENSLOCG00000015180.1|UniProtKB=W5NDH1 W5NDH1 PTHR46845:SF3 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR 1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 LEPOC|Ensembl=ENSLOCG00000001494.1|UniProtKB=W5LZZ7 W5LZZ7 PTHR15503:SF39 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006671.1|UniProtKB=W5MI65 W5MI65 PTHR13817:SF54 TITIN CELL ADHESION MOLECULE DSCAML1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 structural protein#PC00211 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 LEPOC|Ensembl=ENSLOCG00000018334.1|UniProtKB=W5NP76 W5NP76 PTHR24232:SF7 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 20 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002975.1|UniProtKB=W5M568 W5M568 PTHR14963:SF5 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 28 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of signal transduction#GO:0009966;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin filament bundle assembly#GO:0032231;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008147.1|UniProtKB=W5MND4 W5MND4 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001963.1|UniProtKB=W5M1L3 W5M1L3 PTHR24369:SF172 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009262.1|UniProtKB=W5MSE9 W5MSE9 PTHR13958:SF3 CENTROSOME-ASSOCIATED PROTEIN 350 CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000016444.1|UniProtKB=W5NI57 W5NI57 ETV6 PTHR11849:SF19 ETS TRANSCRIPTION FACTOR ETV6 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015992.1|UniProtKB=W5NGD3 W5NGD3 PTHR10501:SF61 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B'' nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U2#P01478 LEPOC|Ensembl=ENSLOCG00000015070.1|UniProtKB=W5ND42 W5ND42 PTHR11547:SF24 ARGININE OR CREATINE KINASE CREATINE KINASE U-TYPE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000008750.1|UniProtKB=W5MQJ4 W5MQJ4 C2orf49 PTHR28359:SF1 ASHWIN ASHWIN LEPOC|Ensembl=ENSLOCG00000018019.1|UniProtKB=W5NNB1 W5NNB1 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001973.1|UniProtKB=W5M1M7 W5M1M7 PTHR15511:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008071.1|UniProtKB=W5MN41 W5MN41 PTHR15243:SF0 SERINE/THREONINE-PROTEIN KINASE 19 SERINE_THREONINE-PROTEIN KINASE 19 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016437.1|UniProtKB=W5NI42 W5NI42 PLCB1 PTHR10336:SF12 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;phospholipase C activity#GO:0004629;calmodulin binding#GO:0005516;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of sequestering of calcium ion#GO:0051282;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;behavior#GO:0007610;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;release of sequestered calcium ion into cytosol#GO:0051209;cellular metabolic process#GO:0044237;nervous system process#GO:0050877;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 CCKR signaling map#P06959>PLC_beta#P07110;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Gonadotropin-releasing hormone receptor pathway#P06664>PLCbeta#P06705;Endogenous cannabinoid signaling#P05730>PLC#P05746;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 LEPOC|Ensembl=ENSLOCG00000007564.1|UniProtKB=W5MLB5 W5MLB5 PTHR40141:SF2 3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED 3',5'-CYCLIC-AMP PHOSPHODIESTERASE LEPOC|Ensembl=ENSLOCG00000010000.1|UniProtKB=W5MV16 W5MV16 PTHR12021:SF3 THYMOSIN BETA THYMOSIN BETA-4-LIKE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 negative regulation of protein polymerization#GO:0032272;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell migration#GO:0030334;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002995.1|UniProtKB=W5M570 W5M570 PTHR12155:SF29 SCHLAFEN SCHLAFEN-LIKE PROTEIN 1 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011910.1|UniProtKB=W5N211 W5N211 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN 4-RELATED microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000001699.1|UniProtKB=W5M0R3 W5M0R3 PTHR11540:SF16 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Lactate Dehydrogenase#P03139 LEPOC|Ensembl=ENSLOCG00000016188.1|UniProtKB=W5NH46 W5NH46 PTHR11404:SF6 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012059.1|UniProtKB=W5N2H3 W5N2H3 EREG PTHR10740:SF11 TRANSFORMING GROWTH FACTOR ALPHA PROEPIREGULIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of mitotic nuclear division#GO:0007088;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of organelle organization#GO:0010638;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of mitotic cell cycle#GO:0007346;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000011141.1|UniProtKB=W5MZ78 W5MZ78 PTHR13843:SF5 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1B cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;actin binding#GO:0003779;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cell projection organization#GO:0030030;dendrite development#GO:0016358;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;anatomical structure morphogenesis#GO:0009653;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cytosol#GO:0005829;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cell body#GO:0044297;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000001956.1|UniProtKB=W5M1K6 W5M1K6 PTHR13313:SF0 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007930.1|UniProtKB=W5MMM0 W5MMM0 PTHR44444:SF4 PROTEIN SEL-1 HOMOLOG 3 PROTEIN SEL-1 HOMOLOG 3 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000004791.1|UniProtKB=W5MBI6 W5MBI6 PTHR31638:SF3 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000017018.1|UniProtKB=W5NK75 W5NK75 FBLN1 PTHR24034:SF97 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-1 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000015168.1|UniProtKB=W5NDF7 W5NDF7 SCYL2 PTHR12984:SF6 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007030.1|UniProtKB=W5MJF4 W5MJF4 PTHR21180:SF32 ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009374.1|UniProtKB=W5MST6 W5MST6 PTHR24213:SF0 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;actomyosin#GO:0042641;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016222.1|UniProtKB=W5NH92 W5NH92 PTHR11003:SF59 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016256.1|UniProtKB=W5NHD7 W5NHD7 CAPS2 PTHR34524:SF3 CALCYPHOSIN CALCYPHOSIN-2 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014539.1|UniProtKB=W5NB85 W5NB85 PTHR10071:SF149 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of angiogenesis#GO:0045765;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of vasculature development#GO:1901342;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 LEPOC|Ensembl=ENSLOCG00000000900.1|UniProtKB=W5LXZ3 W5LXZ3 PTHR14083:SF2 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1A localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000012034.1|UniProtKB=W5N2E7 W5N2E7 SLC9B2 PTHR31102:SF1 FAMILY NOT NAMED CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011150.1|UniProtKB=W5MZ92 W5MZ92 PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED TRANSMEMBRANE PROTEIN 104 LEPOC|Ensembl=ENSLOCG00000017995.1|UniProtKB=W5NN87 W5NN87 PTHR19957:SF30 SYNTAXIN SYNTAXIN-11 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000007336.1|UniProtKB=W5MKH6 W5MKH6 PTHR22611:SF2 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>Naked#P01427 LEPOC|Ensembl=ENSLOCG00000000173.1|UniProtKB=W5LVN7 W5LVN7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014604.1|UniProtKB=W5NBG2 W5NBG2 PTHR11249:SF4 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR GAMMA protein-containing complex binding#GO:0044877;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008763.1|UniProtKB=W5MQK9 W5MQK9 PTHR24205:SF3 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 2 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000016108.1|UniProtKB=W5NGT8 W5NGT8 PTHR11339:SF408 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-5B external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013379.1|UniProtKB=W5N780 W5N780 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015764.1|UniProtKB=W5NFJ7 W5NFJ7 PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010533.1|UniProtKB=W5MWZ5 W5MWZ5 PTHR23351:SF14 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000000373.1|UniProtKB=W5LW99 W5LW99 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017885.1|UniProtKB=W5NMX9 W5NMX9 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011193.1|UniProtKB=W5MZF0 W5MZF0 PTHR16214:SF3 TRANSMEMBRANE PROTEIN 260 TRANSMEMBRANE PROTEIN 260 LEPOC|Ensembl=ENSLOCG00000001826.1|UniProtKB=W5M179 W5M179 PTHR15075:SF5 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012369.1|UniProtKB=W5N3M7 W5N3M7 PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 monosaccharide metabolic process#GO:0005996;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 LEPOC|Ensembl=ENSLOCG00000009655.1|UniProtKB=W5MTU0 W5MTU0 PTHR11037:SF17 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 2 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biosynthetic process#GO:0009889;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;tube development#GO:0035295;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002747.1|UniProtKB=W5M4C3 W5M4C3 PTHR46523:SF1 DCTP PYROPHOSPHATASE 1 DCTP PYROPHOSPHATASE 1 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000008884.1|UniProtKB=W5MR04 W5MR04 PTHR12802:SF155 SWI/SNF COMPLEX-RELATED DEUBIQUITINASE MYSM1 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009892.1|UniProtKB=W5MUM8 W5MUM8 PTHR24340:SF34 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004910.1|UniProtKB=W5MC73 W5MC73 PTHR24223:SF357 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 4 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008671.1|UniProtKB=W5MQ92 W5MQ92 PTHR22803:SF65 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LYMPHOCYTE ANTIGEN 75 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017360.1|UniProtKB=W5NLF6 W5NLF6 PTHR45712:SF12 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT3 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000008291.1|UniProtKB=W5MNW0 W5MNW0 PTHR22957:SF324 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN CARABIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000010988.1|UniProtKB=W5MYL3 W5MYL3 PTHR45476:SF1 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6 ion channel#PC00133;transporter#PC00227 Nicotine pharmacodynamics pathway#P06587>CLIC6#P06611;Dopamine receptor mediated signaling pathway#P05912>CLIC6#P05968 LEPOC|Ensembl=ENSLOCG00000000925.1|UniProtKB=W5LY28 W5LY28 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009021.1|UniProtKB=W5MRJ4 W5MRJ4 PTHR10082:SF15 INTEGRIN BETA SUBUNIT INTEGRIN BETA-2 amyloid-beta binding#GO:0001540;integrin binding#GO:0005178;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;cell adhesion molecule binding#GO:0050839;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;leukocyte cell-cell adhesion#GO:0007159;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;neutrophil chemotaxis#GO:0030593;myeloid leukocyte migration#GO:0097529;integrin-mediated signaling pathway#GO:0007229;leukocyte chemotaxis#GO:0030595;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;neutrophil migration#GO:1990266;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell chemotaxis#GO:0060326;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 LEPOC|Ensembl=ENSLOCG00000012488.1|UniProtKB=W5N434 W5N434 PTHR11616:SF249 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SOLUTE CARRIER FAMILY 6 MEMBER 22, TANDEM DUPLICATE 2 ISOFORM X2-RELATED secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017758.1|UniProtKB=W5NMK3 W5NMK3 PTHR10155:SF11 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 3 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 LEPOC|Ensembl=ENSLOCG00000014853.1|UniProtKB=W5NCC9 W5NCC9 PTHR45820:SF1 FI23527P1 PROTON-COUPLED ZINC ANTIPORTER SLC30A1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;response to stimulus#GO:0050896;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;response to toxic substance#GO:0009636;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005875.1|UniProtKB=W5MFD6 W5MFD6 PRSS56 PTHR24253:SF72 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 56 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006222.1|UniProtKB=W5MGK6 W5MGK6 PLEKHB1 PTHR14309:SF7 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000012770.1|UniProtKB=W5N503 W5N503 ZFAND6 PTHR10634:SF25 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 6 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;cellular process#GO:0009987;peroxisome organization#GO:0007031;establishment of protein localization#GO:0045184;protein localization#GO:0008104 LEPOC|Ensembl=ENSLOCG00000001733.1|UniProtKB=W5M0V1 W5M0V1 RBBP8 PTHR15107:SF4 RETINOBLASTOMA BINDING PROTEIN 8 DNA ENDONUCLEASE RBBP8 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012395.1|UniProtKB=W5N3Q4 W5N3Q4 ELOVL6 PTHR11157:SF68 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000017325.1|UniProtKB=W5NLC1 W5NLC1 PTHR13445:SF3 TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN TSSC4 LEPOC|Ensembl=ENSLOCG00000009283.1|UniProtKB=W5MSH2 W5MSH2 PTHR19878:SF6 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED PROTEIN 16-1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;catabolic process#GO:0009056;autophagosome assembly#GO:0000045;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001897.1|UniProtKB=W5M1G6 W5M1G6 PTHR23280:SF27 4.1 G PROTEIN TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004009.1|UniProtKB=W5M8T2 W5M8T2 PTHR11461:SF48 SERINE PROTEASE INHIBITOR, SERPIN GLIA-DERIVED NEXIN peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of gene expression#GO:0010629;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of hydrolase activity#GO:0051336;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;negative regulation of biosynthetic process#GO:0009890;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000004708.1|UniProtKB=W5MB93 W5MB93 PTHR12442:SF11 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;outer dynein arm#GO:0036157;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006444.1|UniProtKB=W5MHD9 W5MHD9 PTHR19277:SF122 PENTRAXIN PENTRAXIN-4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000737.1|UniProtKB=W5LXG1 W5LXG1 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009056.1|UniProtKB=W5MRN2 W5MRN2 PTHR10807:SF51 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 11 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000012063.1|UniProtKB=W5N2I2 W5N2I2 PTHR10740:SF16 TRANSFORMING GROWTH FACTOR ALPHA AMPHIREGULIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of mitotic nuclear division#GO:0007088;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of organelle organization#GO:0010638;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of mitotic cell cycle#GO:0007346;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000013424.1|UniProtKB=W5N7E6 W5N7E6 PTHR11461:SF290 SERINE PROTEASE INHIBITOR, SERPIN SERINE (OR CYSTEINE) PEPTIDASE INHIBITOR, CLADE H, MEMBER 2 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;external encapsulating structure organization#GO:0045229;regulation of molecular function#GO:0065009;supramolecular fiber organization#GO:0097435;regulation of hydrolase activity#GO:0051336;regulation of proteolysis#GO:0030162;collagen fibril organization#GO:0030199;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000012896.1|UniProtKB=W5N5G4 W5N5G4 PTHR46065:SF1 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCH3-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015398.1|UniProtKB=W5NE86 W5NE86 IAPP PTHR10505:SF4 CALCITONIN-RELATED ISLET AMYLOID POLYPEPTIDE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000012995.1|UniProtKB=W5N5U8 W5N5U8 PTHR11374:SF59 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018145.1|UniProtKB=W5NNN7 W5NNN7 PTHR10666:SF173 UBIQUITIN NEDD8 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein neddylation#GO:0045116;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013851.1|UniProtKB=W5N8X3 W5N8X3 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006231.1|UniProtKB=W5MGL6 W5MGL6 PTHR18976:SF11 APOLIPOPROTEIN APOLIPOPROTEIN A-I cholesterol transfer activity#GO:0120020;molecular function activator activity#GO:0140677;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;binding#GO:0005488;molecular function regulator activity#GO:0098772;sterol transporter activity#GO:0015248;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;phospholipid binding#GO:0005543;enzyme regulator activity#GO:0030234;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;cholesterol metabolic process#GO:0008203;homeostatic process#GO:0042592;alcohol metabolic process#GO:0006066;phospholipid transport#GO:0015914;chemical homeostasis#GO:0048878;lipid transport#GO:0006869;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;cholesterol transport#GO:0030301;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;cholesterol efflux#GO:0033344;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;high-density lipoprotein particle#GO:0034364;organelle#GO:0043226;vesicle#GO:0031982 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000005444.1|UniProtKB=W5MDV2 W5MDV2 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000895.1|UniProtKB=W5LXZ1 W5LXZ1 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;transferase#PC00220;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812 LEPOC|Ensembl=ENSLOCG00000006964.1|UniProtKB=W5MJ77 W5MJ77 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING BOS COMPLEX SUBUNIT NOMO1-RELATED cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014474.1|UniProtKB=W5NB08 W5NB08 PTHR11753:SF10 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009024.1|UniProtKB=W5MRI5 W5MRI5 PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;iron ion transmembrane transport#GO:0034755;mitochondrial transport#GO:0006839;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008411.1|UniProtKB=W5MPB1 W5MPB1 PTHR14725:SF0 RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED LEPOC|Ensembl=ENSLOCG00000007123.1|UniProtKB=W5MJR3 W5MJR3 PTHR11639:SF119 S100 CALCIUM-BINDING PROTEIN PROTEIN S100 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003705.1|UniProtKB=W5M7P9 W5M7P9 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR SMALL RIBOSOMAL SUBUNIT PROTEIN US2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007900.1|UniProtKB=W5MMI3 W5MMI3 PTHR32023:SF2 PILR ALPHA-ASSOCIATED NEURAL PROTEIN PILR ALPHA-ASSOCIATED NEURAL PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009566.1|UniProtKB=W5MTI1 W5MTI1 PTHR45882:SF2 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007116.1|UniProtKB=W5MJR8 W5MJR8 PTHR18860:SF17 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 LEPOC|Ensembl=ENSLOCG00000010226.1|UniProtKB=W5MVV7 W5MVV7 CDKL3 PTHR24056:SF177 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008327.1|UniProtKB=W5MP13 W5MP13 PTHR14699:SF1 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21B cilium organization#GO:0044782;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;plasma membrane bounded cell projection organization#GO:0120036;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 intraciliary transport particle A#GO:0030991;protein-containing complex#GO:0032991;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000010238.1|UniProtKB=W5MVX7 W5MVX7 PTHR19446:SF479 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000012366.1|UniProtKB=W5N3L0 W5N3L0 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 identical protein binding#GO:0042802;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017919.1|UniProtKB=W5NN13 W5NN13 PTHR13318:SF273 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 14 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000011806.1|UniProtKB=W5N1L8 W5N1L8 PTHR23339:SF103 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CYCLIN-DEPENDENT KINASE INHIBITOR 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013788.1|UniProtKB=W5N8P9 W5N8P9 PTHR21346:SF5 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 2 process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle disassembly#GO:1903008;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 LEPOC|Ensembl=ENSLOCG00000011984.1|UniProtKB=W5N2A4 W5N2A4 PTHR44170:SF12 PROTEIN SIDEKICK NEUROFASCIN cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;head development#GO:0060322;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017603.1|UniProtKB=W5NM49 W5NM49 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002299.1|UniProtKB=W5M2S9 W5M2S9 PTHR19305:SF9 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 LEPOC|Ensembl=ENSLOCG00000011075.1|UniProtKB=W5MZ00 W5MZ00 PTHR13793:SF19 PHD FINGER PROTEINS BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017938.1|UniProtKB=W5NN32 W5NN32 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015092.1|UniProtKB=W5ND64 W5ND64 PTHR34441:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006205.1|UniProtKB=W5MGI7 W5MGI7 RAB6A PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000383.1|UniProtKB=W5LWB1 W5LWB1 PTHR23076:SF97 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006920.1|UniProtKB=W5MJ05 W5MJ05 MOCS2 PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016400.1|UniProtKB=W5NHZ3 W5NHZ3 PTHR31893:SF4 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151B LEPOC|Ensembl=ENSLOCG00000016046.1|UniProtKB=W5NGK6 W5NGK6 PTHR16156:SF10 AFTIPHILIN A-RELATED AFTIPHILIN-RELATED protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network membrane#GO:0032588;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;membrane protein complex#GO:0098796;trans-Golgi network#GO:0005802;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000003685.1|UniProtKB=W5M7N3 W5M7N3 PTHR13155:SF1 A-KINASE ANCHOR PROTEINS A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005588.1|UniProtKB=W5MED6 W5MED6 CFAP77 PTHR28617:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015892.1|UniProtKB=W5NG13 W5NG13 PTHR11214:SF219 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010718.1|UniProtKB=W5MXM5 W5MXM5 PTHR18945:SF221 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011408.1|UniProtKB=W5N072 W5N072 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 LEPOC|Ensembl=ENSLOCG00000017097.1|UniProtKB=W5NKG9 W5NKG9 PTHR12289:SF76 METAXIN RELATED FAILED AXON CONNECTIONS HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005677.1|UniProtKB=W5MEP6 W5MEP6 PTHR13430:SF4 FAMILY NOT NAMED AUTOPHAGY-RELATED PROTEIN 13 cellular component assembly#GO:0022607;microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;mitophagy#GO:0000423;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011681.1|UniProtKB=W5N148 W5N148 PTHR15902:SF1 NEURITIN-RELATED NEURITIN cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;neurogenesis#GO:0022008;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;growth#GO:0040007;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;cell growth#GO:0016049;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017922.1|UniProtKB=W5NN16 W5NN16 PTHR46131:SF2 SD08549P MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A51-RELATED purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018340.1|UniProtKB=W5NP82 W5NP82 PTHR22750:SF5 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003049.1|UniProtKB=W5M5I1 W5M5I1 PTHR11731:SF21 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10 catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;transporter regulator activity#GO:0141108;peptidase activity#GO:0008233;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;regulation of metal ion transport#GO:0010959;organonitrogen compound metabolic process#GO:1901564;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011728.1|UniProtKB=W5N1B2 W5N1B2 PTHR45723:SF2 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO1 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017240.1|UniProtKB=W5NL14 W5NL14 TRERF1 PTHR16089:SF19 REST COREPRESSOR COREST PROTEIN-RELATED TRANSCRIPTIONAL-REGULATING FACTOR 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008649.1|UniProtKB=W5MQ54 W5MQ54 PTHR12788:SF6 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 peptidyl-tyrosine modification#GO:0018212;sulfur compound metabolic process#GO:0006790;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006438.1|UniProtKB=W5MHC3 W5MHC3 PTHR13028:SF0 RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED RRNA-PROCESSING PROTEIN EBP2-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;nuclear periphery#GO:0034399;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000011789.1|UniProtKB=W5N1I9 W5N1I9 PTHR15129:SF2 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 2 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015876.1|UniProtKB=W5NFZ2 W5NFZ2 PTHR24322:SF734 PKSB EPIDERMAL RETINOL DEHYDROGENASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016939.1|UniProtKB=W5NJY3 W5NJY3 PTHR18945:SF197 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017356.1|UniProtKB=W5NLF2 W5NLF2 PTHR14520:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 63 LARGE RIBOSOMAL SUBUNIT PROTEIN ML63 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005290.1|UniProtKB=W5MDB6 W5MDB6 PTHR24271:SF81 KALLIKREIN-RELATED GRANZYME B serine protease#PC00203;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Granzyme B#P00265 LEPOC|Ensembl=ENSLOCG00000012403.1|UniProtKB=W5N3R2 W5N3R2 PTHR10005:SF7 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;negative regulation of BMP signaling pathway#GO:0030514;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of DNA-templated transcription#GO:0006355;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016237.1|UniProtKB=W5NHB1 W5NHB1 PTHR23506:SF26 GH10249P MFS-TYPE TRANSPORTER SLC18B1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000293.1|UniProtKB=W5LW14 W5LW14 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000011966.1|UniProtKB=W5N255 W5N255 PTHR45689:SF3 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;regulation of membrane depolarization#GO:0003254;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006573.1|UniProtKB=W5MHS7 W5MHS7 PTHR17469:SF11 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID2 LEPOC|Ensembl=ENSLOCG00000006432.1|UniProtKB=W5MHB1 W5MHB1 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE_THREONINE-PROTEIN KINASE RIO2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;preribosome#GO:0030684;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017340.1|UniProtKB=W5NLD6 W5NLD6 B3GALT9 PTHR11214:SF29 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 9 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000005836.1|UniProtKB=W5MFB0 W5MFB0 PTHR11010:SF38 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013089.1|UniProtKB=W5N668 W5N668 PTHR45711:SF8 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 3 voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;Golgi apparatus#GO:0005794;cell junction#GO:0030054;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004187.1|UniProtKB=W5M9D6 W5M9D6 PTHR21402:SF10 GAMETOCYTE SPECIFIC FACTOR 1-RELATED U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN LEPOC|Ensembl=ENSLOCG00000008643.1|UniProtKB=W5MQ67 W5MQ67 PTHR23250:SF1 DYSFERLIN-RELATED TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007495.1|UniProtKB=W5ML55 W5ML55 PTHR23113:SF175 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012785.1|UniProtKB=W5N523 W5N523 PTHR10185:SF8 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD4 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000017130.1|UniProtKB=W5NKL3 W5NKL3 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007076.1|UniProtKB=W5MJK7 W5MJK7 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015265.1|UniProtKB=W5NDS6 W5NDS6 PTHR11085:SF2 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NOVEL PROTEIN SIMILAR TO VERTEBRATE SIRTUIN (SILENT MATING TYPE INFORMATION REGULATION 2 HOMOLOG) 2 (S. CEREVISIAE) (SIRT2) nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000872.1|UniProtKB=W5LXW8 W5LXW8 PTHR11630:SF73 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004859.1|UniProtKB=W5MBS9 W5MBS9 PTHR14215:SF1 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1 cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organelle organization#GO:0006996;generation of precursor metabolites and energy#GO:0006091;organelle fission#GO:0048285;cellular metabolic process#GO:0044237;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial fission#GO:0000266;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007561.1|UniProtKB=W5MLB7 W5MLB7 PTHR24356:SF1 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE GREATWALL non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013867.1|UniProtKB=W5N8Z8 W5N8Z8 PTHR19431:SF0 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008907.1|UniProtKB=W5MR38 W5MR38 PTHR46986:SF1 ENDORIBONUCLEASE YBEY, CHLOROPLASTIC ENDORIBONUCLEASE YBEY, CHLOROPLASTIC endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000064.1|UniProtKB=W5LVB7 W5LVB7 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013950.1|UniProtKB=W5N989 W5N989 ARL16 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 LEPOC|Ensembl=ENSLOCG00000004569.1|UniProtKB=W5MAT3 W5MAT3 PTHR10336:SF173 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;positive regulation of cell motility#GO:2000147;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;regulation of multicellular organismal process#GO:0051239;transmembrane transport#GO:0055085;regulation of cell motility#GO:2000145;calcium ion transmembrane transport#GO:0070588;positive regulation of locomotion#GO:0040017;release of sequestered calcium ion into cytosol#GO:0051209;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 VEGF signaling pathway#P00056>PLC-gamma#P01414;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;FGF signaling pathway#P00021>PLCgamma#P00638;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;EGF receptor signaling pathway#P00018>PLCgamma#P00556;PDGF signaling pathway#P00047>PLCgamma#P01171;T cell activation#P00053>PLC-gamma#P01320;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;CCKR signaling map#P06959>PLCgamma1#P07037 LEPOC|Ensembl=ENSLOCG00000011064.1|UniProtKB=W5MYY6 W5MYY6 PTHR45739:SF7 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000638.1|UniProtKB=W5LX47 W5LX47 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003901.1|UniProtKB=W5M8E7 W5M8E7 PTHR23419:SF2 DIVALENT CATION TOLERANCE CUTA-RELATED CUTA DIVALENT CATION TOLERANCE HOMOLOG-LIKE copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018300.1|UniProtKB=W5NP42 W5NP42 PTHR11984:SF12 CONNEXIN GAP JUNCTION ALPHA-3 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000014043.1|UniProtKB=W5N9K3 W5N9K3 PTHR46055:SF2 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Circadian clock system#P00015>Clock#P00501 LEPOC|Ensembl=ENSLOCG00000015063.1|UniProtKB=W5ND28 W5ND28 PTHR17490:SF14 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004158.1|UniProtKB=W5M9B7 W5M9B7 PTHR20859:SF85 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA_BETA RECEPTOR 1 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000795.1|UniProtKB=W5LXN1 W5LXN1 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 CROSSOVER JUNCTION ENDONUCLEASE MUS81 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;reciprocal meiotic recombination#GO:0007131;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic DNA integrity checkpoint signaling#GO:0044774;homologous recombination#GO:0035825;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012993.1|UniProtKB=W5N5U4 W5N5U4 PTHR43107:SF23 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN VERY LONG-CHAIN ACYL-COA SYNTHETASE long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;import into cell#GO:0098657;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007155.1|UniProtKB=W5MJV5 W5MJV5 PTHR22802:SF342 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-154O6.6 PROTEIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003180.1|UniProtKB=W5M5V0 W5M5V0 UPK2 PTHR17573:SF0 UROPLAKIN II UROPLAKIN-2 LEPOC|Ensembl=ENSLOCG00000013798.1|UniProtKB=W5N8Q2 W5N8Q2 PTHR12884:SF0 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000018124.1|UniProtKB=W5NNL6 W5NNL6 PTHR10129:SF30 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000007026.1|UniProtKB=W5MJF7 W5MJF7 PTHR10333:SF106 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 4 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of programmed cell death#GO:0043068;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of programmed cell death#GO:0043067;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010336.1|UniProtKB=W5MWA5 W5MWA5 PTHR24064:SF453 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 5 transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007309.1|UniProtKB=W5MKE0 W5MKE0 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000011554.1|UniProtKB=W5N0N9 W5N0N9 PTHR14167:SF64 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009680.1|UniProtKB=W5MTW5 W5MTW5 PTHR21519:SF1 PDZ DOMAIN-CONTAINING PROTEIN 8 PDZ DOMAIN-CONTAINING PROTEIN 8 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;organelle localization#GO:0051640;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular component organization#GO:0016043;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intracellular monoatomic cation homeostasis#GO:0030003;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873 cellular anatomical entity#GO:0110165;organelle membrane contact site#GO:0044232;organelle#GO:0043226;mitochondria-associated endoplasmic reticulum membrane#GO:0044233 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002234.1|UniProtKB=W5M2I9 W5M2I9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003991.1|UniProtKB=W5M8R5 W5M8R5 PPEF2 PTHR45668:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 2 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;Hsp90 protein binding#GO:0051879 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000717.1|UniProtKB=W5LXE5 W5LXE5 PTHR21551:SF2 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;P-body assembly#GO:0033962;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;non-membrane-bounded organelle assembly#GO:0140694;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016631.1|UniProtKB=W5NIU3 W5NIU3 PTHR10166:SF59 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013117.1|UniProtKB=W5N696 W5N696 C15orf48 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT NORMAL MUCOSA OF ESOPHAGUS-SPECIFIC GENE 1 PROTEIN envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006482.1|UniProtKB=W5MHH0 W5MHH0 PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008365.1|UniProtKB=W5MP52 W5MP52 PTHR10529:SF236 AP COMPLEX SUBUNIT MU AP-2 COMPLEX SUBUNIT MU localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CCKR signaling map#P06959>AP2M1#P07067 LEPOC|Ensembl=ENSLOCG00000002491.1|UniProtKB=W5M3H7 W5M3H7 PTHR13482:SF3 MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8 MICROPROCESSOR COMPLEX SUBUNIT DGCR8 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;primary miRNA processing#GO:0031053;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;endoribonuclease complex#GO:1902555;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000002561.1|UniProtKB=W5M3Q0 W5M3Q0 PTHR47027:SF29 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007501.1|UniProtKB=W5ML46 W5ML46 PTHR23024:SF108 ARYLACETAMIDE DEACETYLASE NEUTRAL CHOLESTEROL ESTER HYDROLASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 deacetylase#PC00087;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001132.1|UniProtKB=W5LYU6 W5LYU6 PTHR46841:SF4 OX-2 MEMBRANE GLYCOPROTEIN SC:D189 LEPOC|Ensembl=ENSLOCG00000003281.1|UniProtKB=W5M659 W5M659 PTHR31767:SF0 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000001654.1|UniProtKB=W5M0M1 W5M0M1 PTHR24170:SF2 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;SNARE binding#GO:0000149;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 endosomal transport#GO:0016197;cellular localization#GO:0051641;neurogenesis#GO:0022008;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;anatomical structure development#GO:0048856;establishment of localization in cell#GO:0051649;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;generation of neurons#GO:0048699;early endosome to late endosome transport#GO:0045022 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cell projection#GO:0042995;late endosome#GO:0005770;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011859.1|UniProtKB=W5N1T6 W5N1T6 PTHR23065:SF57 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 7 cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;receptor-mediated endocytosis#GO:0006898;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;clathrin-dependent endocytosis#GO:0072583;multicellular organism development#GO:0007275;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;import into cell#GO:0098657 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001902.1|UniProtKB=W5M1F5 W5M1F5 PTHR10026:SF8 CYCLIN CYCLIN-H protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of catalytic activity#GO:0050790;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000004382.1|UniProtKB=W5MA42 W5MA42 PTHR11373:SF4 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;nucleoside triphosphate catabolic process#GO:0009143;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000904.1|UniProtKB=W5LXZ8 W5LXZ8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011888.1|UniProtKB=W5N1V7 W5N1V7 PTHR23057:SF0 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011648.1|UniProtKB=W5N100 W5N100 PTHR24336:SF9 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007808.1|UniProtKB=W5MM72 W5MM72 PTHR23159:SF47 CENTROSOMAL PROTEIN 2 TRICHOHYALIN chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000839.1|UniProtKB=W5LXT1 W5LXT1 PTHR16024:SF15 XK-RELATED PROTEIN XK-RELATED PROTEIN 5 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015751.1|UniProtKB=W5NFI1 W5NFI1 PTHR23093:SF16 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 FAM194 C-TERMINAL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017426.1|UniProtKB=W5NLM2 W5NLM2 PTHR12649:SF11 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000014409.1|UniProtKB=W5NAT0 W5NAT0 PRKAR2A PTHR11635:SF153 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT protein kinase A binding#GO:0051018;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570 LEPOC|Ensembl=ENSLOCG00000004157.1|UniProtKB=W5M9B3 W5M9B3 SGPP2 PTHR14969:SF14 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015238.1|UniProtKB=W5NDP2 W5NDP2 PTHR13112:SF1 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3B RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of amide metabolic process#GO:0034248;RNA metabolic process#GO:0016070;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;positive regulation of protein metabolic process#GO:0051247;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010907.1|UniProtKB=W5MYC3 W5MYC3 PTHR11274:SF0 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB DNA metabolism protein#PC00009;DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000006094.1|UniProtKB=W5MG58 W5MG58 PTHR22538:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74 LEPOC|Ensembl=ENSLOCG00000006050.1|UniProtKB=W5MFZ4 W5MFZ4 PTHR24355:SF1 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-RELATED PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006340.1|UniProtKB=W5MGZ7 W5MGZ7 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 basal RNA polymerase II transcription machinery binding#GO:0001099;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 LEPOC|Ensembl=ENSLOCG00000009829.1|UniProtKB=W5MUF8 W5MUF8 PTHR13318:SF19 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 5 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000016266.1|UniProtKB=W5NHF4 W5NHF4 PTHR45570:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017959.1|UniProtKB=W5NN53 W5NN53 PTHR24366:SF15 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN 2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000011326.1|UniProtKB=W5MZV6 W5MZV6 PTHR13817:SF67 TITIN MYOPALLADIN structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000018002.1|UniProtKB=W5NN94 W5NN94 PTHR46341:SF1 PROTEIN FAM84B-RELATED PROTEIN LRATD1 cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000002667.1|UniProtKB=W5M448 W5M448 PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 LEPOC|Ensembl=ENSLOCG00000008445.1|UniProtKB=W5MPG8 W5MPG8 PTHR10048:SF22 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000001751.1|UniProtKB=W5M0W6 W5M0W6 PTHR23244:SF462 KELCH REPEAT DOMAIN KELCH REPEAT-CONTAINING PROTEIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000015693.1|UniProtKB=W5NFA9 W5NFA9 PET117 PTHR28163:SF1 PROTEIN PET117 HOMOLOG, MITOCHONDRIAL PROTEIN PET117 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016748.1|UniProtKB=W5NJ93 W5NJ93 PTHR10088:SF4 GLUCOKINASE REGULATORY PROTEIN GLUCOKINASE REGULATORY PROTEIN protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007855.1|UniProtKB=W5MMC8 W5MMC8 PTHR11200:SF127 INOSITOL 5-PHOSPHATASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;glycerolipid metabolic process#GO:0046486;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;negative regulation of phosphorus metabolic process#GO:0010563;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cell leading edge#GO:0031252;cytoplasm#GO:0005737;ruffle#GO:0001726;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000002204.1|UniProtKB=W5M2F6 W5M2F6 C4orf48 PTHR35451:SF1 NEUROPEPTIDE-LIKE PROTEIN C4ORF48 NEUROPEPTIDE-LIKE PROTEIN C4ORF48 LEPOC|Ensembl=ENSLOCG00000003372.1|UniProtKB=W5M6H7 W5M6H7 PTHR12015:SF186 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 21-LIKE-RELATED cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013255.1|UniProtKB=W5N6S0 W5N6S0 PTHR10846:SF61 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 5 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015176.1|UniProtKB=W5NDG4 W5NDG4 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005764.1|UniProtKB=W5MF03 W5MF03 C1QA PTHR15427:SF26 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001393.1|UniProtKB=W5LZN2 W5LZN2 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 negative regulation of sister chromatid segregation#GO:0033046;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;organelle localization#GO:0051640;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of mitotic sister chromatid segregation#GO:0033047;attachment of spindle microtubules to kinetochore#GO:0008608;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;establishment of organelle localization#GO:0051656;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;mitotic metaphase chromosome alignment#GO:0007080;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromosome localization#GO:0050000;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of organelle organization#GO:0010639;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;establishment of chromosome localization#GO:0051303;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;metaphase chromosome alignment#GO:0051310 envelope#GO:0031975;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nuclear envelope#GO:0005635;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;mitotic spindle#GO:0072686;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000017015.1|UniProtKB=W5NK77 W5NK77 PTHR11584:SF332 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ERK#P00907;FAS signaling pathway#P00020>ASK1#P00614;p38 MAPK pathway#P05918>ASK1#P06043;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Apoptosis signaling pathway#P00006>ASK1#P00272 LEPOC|Ensembl=ENSLOCG00000004417.1|UniProtKB=W5MA70 W5MA70 PTHR24264:SF68 TRYPSIN-RELATED TRYPSIN-3-LIKE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007172.1|UniProtKB=W5MJY6 W5MJY6 PTHR24115:SF513 KINESIN-RELATED KINESIN-1 HEAVY CHAIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515 neuron projection guidance#GO:0097485;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;synaptic vesicle transport#GO:0048489;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;microtubule-based transport#GO:0099111;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;generation of neurons#GO:0048699;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000013026.1|UniProtKB=W5N5Y3 W5N5Y3 PTHR12122:SF4 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 phosphodiesterase#PC00185;hydrolase#PC00121 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEgamma#P00754 LEPOC|Ensembl=ENSLOCG00000011442.1|UniProtKB=W5N098 W5N098 PDGFB PTHR11633:SF2 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT B growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 PDGF signaling pathway#P00047>PDGF#P01170;Angiogenesis#P00005>PDGF#P00224 LEPOC|Ensembl=ENSLOCG00000014739.1|UniProtKB=W5NBY9 W5NBY9 PTHR23189:SF15 RNA RECOGNITION MOTIF-CONTAINING NON-POU DOMAIN-CONTAINING OCTAMER-BINDING PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008380.1|UniProtKB=W5MP89 W5MP89 PTHR15696:SF7 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018369.1|UniProtKB=W5NPB1 W5NPB1 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011260.1|UniProtKB=W5MZM7 W5MZM7 PTHR14614:SF164 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTONE-ARGININE METHYLTRANSFERASE METTL23 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012065.1|UniProtKB=W5N2L3 W5N2L3 PTHR11453:SF12 ANION EXCHANGE PROTEIN BAND 3 ANION TRANSPORT PROTEIN transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015460.1|UniProtKB=W5NEG9 W5NEG9 PTHR46330:SF6 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B HEMATOPOIETIC DEATH RECEPTOR-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002989.1|UniProtKB=W5M562 W5M562 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007463.1|UniProtKB=W5ML18 W5ML18 PTHR23412:SF21 STEREOCILIN RELATED OTOANCORIN ISOFORM X1 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008899.1|UniProtKB=W5MR40 W5MR40 PTHR11616:SF38 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Dopamine receptor mediated signaling pathway#P05912>DAT#P05962;Adrenaline and noradrenaline biosynthesis#P00001>DAT#P00065;Parkinson disease#P00049>DAT#P01228;Parkinson disease#P00049>DAT#G01547 LEPOC|Ensembl=ENSLOCG00000012050.1|UniProtKB=W5N2G5 W5N2G5 PTHR46388:SF2 NHL REPEAT-CONTAINING PROTEIN 2 NHL REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000010102.1|UniProtKB=W5MVF1 W5MVF1 PTHR12121:SF33 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000007478.1|UniProtKB=W5ML25 W5ML25 PTHR13710:SF108 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q4 ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000018122.1|UniProtKB=W5NNL4 W5NNL4 PTHR24388:SF99 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF52.1-LIKE ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006120.1|UniProtKB=W5MG88 W5MG88 PTHR23098:SF7 AGAP001331-PA-RELATED NUCLEAR APOPTOSIS-INDUCING FACTOR 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018176.1|UniProtKB=W5NNR8 W5NNR8 PTHR24366:SF120 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005678.1|UniProtKB=W5MEQ0 W5MEQ0 PTHR11675:SF47 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 13 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016163.1|UniProtKB=W5NH09 W5NH09 PTHR23101:SF51 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016785.1|UniProtKB=W5NJD7 W5NJD7 PTHR21676:SF1 PROTEIN STUM PROTEIN STUM HOMOLOG LEPOC|Ensembl=ENSLOCG00000003571.1|UniProtKB=W5M774 W5M774 PTHR11610:SF146 LIPASE LIPOPROTEIN LIPASE-LIKE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;triglyceride lipase activity#GO:0004806 regulation of biological process#GO:0050789;lipid metabolic process#GO:0006629;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008005.1|UniProtKB=W5MMW5 W5MMW5 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005479.1|UniProtKB=W5ME05 W5ME05 C5 PTHR11412:SF83 MACROGLOBULIN / COMPLEMENT COMPLEMENT C5 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013453.1|UniProtKB=W5N7H5 W5N7H5 PTHR45970:SF5 AGAP004664-PA HOMEOBOX PROTEIN HOX-B9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002925.1|UniProtKB=W5M511 W5M511 PTHR19237:SF22 NUCLEOBINDIN NUCLEOBINDIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000000546.1|UniProtKB=W5LWU5 W5LWU5 PTHR28579:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein K11-linked ubiquitination#GO:0070979;regulation of mitotic cell cycle#GO:0007346;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004780.1|UniProtKB=W5MBH4 W5MBH4 PTHR15135:SF3 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 regulation of metal ion transport#GO:0010959;system process#GO:0003008;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;skeletal muscle contraction#GO:0003009;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of protein localization to membrane#GO:1905475;regulation of calcium ion transport#GO:0051924;positive regulation of transport#GO:0051050;nervous system process#GO:0050877;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;positive regulation of cellular process#GO:0048522;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of protein localization#GO:1903829;muscle system process#GO:0003012;muscle contraction#GO:0006936 LEPOC|Ensembl=ENSLOCG00000004211.1|UniProtKB=W5M9H4 W5M9H4 PTHR16024:SF8 XK-RELATED PROTEIN XK-RELATED PROTEIN 8 execution phase of apoptosis#GO:0097194;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;programmed cell death#GO:0012501;phospholipid transport#GO:0015914;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;biological regulation#GO:0065007;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014496.1|UniProtKB=W5NB32 W5NB32 PTHR20937:SF18 IP14615P BHLH TRANSCRIPTION FACTOR MESP-B-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;mesoderm formation#GO:0001707;epithelium development#GO:0060429;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;gastrulation#GO:0007369;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;regionalization#GO:0003002;multicellular organism development#GO:0007275;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;mesoderm development#GO:0007498;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018213.1|UniProtKB=W5NNV5 W5NNV5 PTHR26451:SF866 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007159.1|UniProtKB=W5MJV4 W5MJV4 LRRC75A PTHR39654:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75A-LIKE ISOFORM X1 LEUCINE RICH REPEAT CONTAINING 75A LEPOC|Ensembl=ENSLOCG00000009704.1|UniProtKB=W5MTZ1 W5MTZ1 PTHR11685:SF111 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19A ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016337.1|UniProtKB=W5NHS9 W5NHS9 PTHR23043:SF8 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;response to oxygen levels#GO:0070482 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000007452.1|UniProtKB=W5MKY2 W5MKY2 PTHR19269:SF38 TROPOMYOSIN TROPOMYOSIN ALPHA-3 CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000013584.1|UniProtKB=W5N801 W5N801 PTHR23239:SF180 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 17 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001567.1|UniProtKB=W5M085 W5M085 PTHR10159:SF108 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 8 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000015390.1|UniProtKB=W5NE79 W5NE79 PTHR21493:SF79 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1B cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008861.1|UniProtKB=W5MQX7 W5MQX7 PTHR44984:SF1 SERINE/THREONINE-PROTEIN KINASE NEK3 SERINE_THREONINE-PROTEIN KINASE NEK3 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008924.1|UniProtKB=W5MR57 W5MR57 PTHR24200:SF14 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR CANDIDATE 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001242.1|UniProtKB=W5LZ57 W5LZ57 PTHR10201:SF297 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-20 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010523.1|UniProtKB=W5MX02 W5MX02 PTHR11636:SF84 POU DOMAIN NETRIN-1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 LEPOC|Ensembl=ENSLOCG00000003500.1|UniProtKB=W5M700 W5M700 PTHR48083:SF2 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007092.1|UniProtKB=W5MJM9 W5MJM9 PTHR11211:SF47 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS HOMEOBOX PROTEIN 6A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009580.1|UniProtKB=W5MTJ7 W5MTJ7 PTHR21663:SF1 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004580.1|UniProtKB=W5MAX0 W5MAX0 PTHR11405:SF53 CARBAMOYLTRANSFERASE FAMILY MEMBER CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 LEPOC|Ensembl=ENSLOCG00000014747.1|UniProtKB=W5NBZ8 W5NBZ8 VMA21 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008912.1|UniProtKB=W5MR43 W5MR43 PTHR13254:SF2 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7B cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000004093.1|UniProtKB=W5M940 W5M940 PTHR43272:SF13 LONG-CHAIN-FATTY-ACID--COA LIGASE FATTY ACID COA LIGASE ACSL3 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;neurogenesis#GO:0022008;sulfur compound metabolic process#GO:0006790;developmental process#GO:0032502;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;neuron differentiation#GO:0030182;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;generation of neurons#GO:0048699;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010782.1|UniProtKB=W5MXV6 W5MXV6 PTHR13723:SF40 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000020988.1|UniProtKB=Q8HQM7 Q8HQM7 COIII PTHR11403:SF7 CYTOCHROME C OXIDASE SUBUNIT III CYTOCHROME C OXIDASE SUBUNIT 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular metabolic process#GO:0044237;cellular respiration#GO:0045333;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012571.1|UniProtKB=W5N4B6 W5N4B6 PTHR12630:SF22 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;liver development#GO:0001889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;primary metabolic process#GO:0044238;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005679.1|UniProtKB=W5MEP7 W5MEP7 PTHR23235:SF19 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012743.1|UniProtKB=W5N4W7 W5N4W7 HPS6 PTHR14696:SF2 HERMANSKY-PUDLAK SYNDROME 6 PROTEIN BLOC-2 COMPLEX MEMBER HPS6 lysosome localization#GO:0032418;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;organelle localization#GO:0051640;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006457.1|UniProtKB=W5MHD8 W5MHD8 PTHR33865:SF3 PROTEIN FAM183B PROTEIN FAM183B membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary base#GO:0097546 LEPOC|Ensembl=ENSLOCG00000006134.1|UniProtKB=W5MGA6 W5MGA6 PTHR10623:SF7 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;non-membrane-bounded organelle assembly#GO:0140694;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000009648.1|UniProtKB=W5MTT0 W5MTT0 TM4SF20 PTHR14198:SF17 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 20 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014019.1|UniProtKB=W5N9H2 W5N9H2 PTHR12137:SF33 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 14 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017236.1|UniProtKB=W5NL09 W5NL09 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006890.1|UniProtKB=W5MIX6 W5MIX6 RARB PTHR24085:SF5 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013278.1|UniProtKB=W5N6V2 W5N6V2 PTHR19957:SF124 SYNTAXIN SYNTAXIN-8 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017190.1|UniProtKB=W5NKT6 W5NKT6 PTHR47130:SF3 SI:DKEY-19B23.11-RELATED ZONA PELLUCIDA PROTEIN LEPOC|Ensembl=ENSLOCG00000013674.1|UniProtKB=W5N8A0 W5N8A0 PTHR15749:SF4 FANCONI-ASSOCIATED NUCLEASE 1 FANCONI-ASSOCIATED NUCLEASE 1 LEPOC|Ensembl=ENSLOCG00000017777.1|UniProtKB=W5NMM2 W5NMM2 PTHR45773:SF1 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 6 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004705.1|UniProtKB=W5MB78 W5MB78 PTHR15326:SF8 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2 regulation of cell communication#GO:0010646;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein K63-linked deubiquitination#GO:0070536;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002286.1|UniProtKB=W5M2W1 W5M2W1 PTHR12809:SF2 MEDIATOR COMPLEX SUBUNIT MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000010770.1|UniProtKB=W5MXT1 W5MXT1 BRK1 PTHR33668:SF1 PROTEIN BRICK1 PROTEIN BRICK1 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;regulation of actin polymerization or depolymerization#GO:0008064;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008010.1|UniProtKB=W5MMX3 W5MMX3 PTHR21228:SF29 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA processing#GO:0000963;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000002054.1|UniProtKB=W5M1X4 W5M1X4 PTHR46599:SF2 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000015423.1|UniProtKB=W5NEC1 W5NEC1 PTHR14399:SF4 P53-INDUCED PROTEIN RELATED P53 APOPTOSIS EFFECTOR RELATED TO PMP-22 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 p53 pathway#P00059>PERP#G01565 LEPOC|Ensembl=ENSLOCG00000009098.1|UniProtKB=W5MRU1 W5MRU1 PTHR47219:SF7 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1-LIKE nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016902.1|UniProtKB=W5NJT6 W5NJT6 PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83A-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000013386.1|UniProtKB=W5N792 W5N792 PTHR23266:SF345 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA-LIKE POLYPEPTIDE 1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004960.1|UniProtKB=W5MC53 W5MC53 PTHR24208:SF106 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013050.1|UniProtKB=W5N612 W5N612 PTHR46272:SF1 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 142-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011336.1|UniProtKB=W5MZY0 W5MZY0 PTHR18950:SF0 PROGESTERONE-INDUCED BLOCKING FACTOR 1 PROGESTERONE IMMUNOMODULATORY BINDING FACTOR 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006618.1|UniProtKB=W5MHY6 W5MHY6 PTHR22980:SF0 CORTISTATIN CENTROMERE PROTEIN S protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;DNA-templated DNA replication#GO:0006261;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;replication fork processing#GO:0031297;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 neuropeptide#PC00162;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000001779.1|UniProtKB=W5M101 W5M101 PTHR43725:SF47 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 LEPOC|Ensembl=ENSLOCG00000000457.1|UniProtKB=W5LWJ3 W5LWJ3 PTHR11309:SF90 FRIZZLED FRIZZLED-8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000001999.1|UniProtKB=W5M1Q2 W5M1Q2 PTHR23129:SF1 ACYL-COENZYME A DIPHOSPHATASE FITM2 ACYL-COENZYME A DIPHOSPHATASE FITM2 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;maintenance of location#GO:0051235;organophosphate metabolic process#GO:0019637;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003336.1|UniProtKB=W5M6D5 W5M6D5 PTHR22145:SF2 SI:CH211-266K22.6 SI:CH211-266K22.6 LEPOC|Ensembl=ENSLOCG00000013430.1|UniProtKB=W5N7E9 W5N7E9 PTHR11304:SF34 EPHRIN EPHRIN-B3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003294.1|UniProtKB=W5M678 W5M678 SCTR PTHR45620:SF13 PDF RECEPTOR-LIKE PROTEIN-RELATED SECRETIN RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017127.1|UniProtKB=W5NKK6 W5NKK6 FAM162B PTHR13674:SF3 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162B LEPOC|Ensembl=ENSLOCG00000002679.1|UniProtKB=W5M455 W5M455 PTHR10846:SF28 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 3-LIKE ISOFORM X1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011920.1|UniProtKB=W5N202 W5N202 PTHR24214:SF0 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 7 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001264.1|UniProtKB=W5LZ73 W5LZ73 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010084.1|UniProtKB=W5MVC6 W5MVC6 PTHR10937:SF10 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;cellular aromatic compound metabolic process#GO:0006725;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;UDP-N-acetylglucosamine metabolic process#GO:0006047;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;protein N-linked glycosylation#GO:0006487;amino sugar metabolic process#GO:0006040;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 LEPOC|Ensembl=ENSLOCG00000009022.1|UniProtKB=W5MRI2 W5MRI2 PTHR17068:SF12 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000013449.1|UniProtKB=W5N7H4 W5N7H4 PTHR10210:SF28 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000002664.1|UniProtKB=W5M426 W5M426 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC-CHELATE REDUCTASE 1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001222.1|UniProtKB=W5LZ26 W5LZ26 PTHR12197:SF184 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000015426.1|UniProtKB=W5NEC3 W5NEC3 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012882.1|UniProtKB=W5N5F0 W5N5F0 PTHR22461:SF1 SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2-RELATED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000014037.1|UniProtKB=W5N9J3 W5N9J3 NMU PTHR15390:SF0 NEUROMEDIN-U NEUROMEDIN-U LEPOC|Ensembl=ENSLOCG00000005777.1|UniProtKB=W5MF14 W5MF14 PTHR12253:SF17 RH14732P PROTEIN PROCA1 LEPOC|Ensembl=ENSLOCG00000003845.1|UniProtKB=W5M882 W5M882 PTHR31594:SF11 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN NEOVERRUCOTOXIN SUBUNIT ALPHA-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000006318.1|UniProtKB=W5MGX3 W5MGX3 PTHR11533:SF42 PROTEASE M1 ZINC METALLOPROTEASE LEUCYL-CYSTINYL AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 blood circulation#GO:0008015;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;system process#GO:0003008;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;circulatory system process#GO:0003013;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;regulation of blood pressure#GO:0008217;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009284.1|UniProtKB=W5MSI1 W5MSI1 PTHR45725:SF16 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1 actomyosin#GO:0042641;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005458.1|UniProtKB=W5MDX8 W5MDX8 PTHR24044:SF411 NOTCH LIGAND FAMILY MEMBER SUSHI, NIDOGEN AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012640.1|UniProtKB=W5N4J9 W5N4J9 PTHR13182:SF8 ZINC FINGER PROTEIN 622 CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;preribosome, large subunit precursor#GO:0030687 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014259.1|UniProtKB=W5NA95 W5NA95 PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000014949.1|UniProtKB=W5NCP6 W5NCP6 PTHR11636:SF44 POU DOMAIN BRAIN-SPECIFIC HOMEOBOX_POU DOMAIN PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014421.1|UniProtKB=W5NAU6 W5NAU6 PTHR11769:SF36 HYALURONIDASE HYALURONIDASE glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005020.1|UniProtKB=W5MCD5 W5MCD5 PTHR12357:SF65 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 1 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of mRNA metabolic process#GO:1903313;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;mRNA destabilization#GO:0061157;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016107.1|UniProtKB=W5NGT7 W5NGT7 LRRTM4 PTHR24366:SF120 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005142.1|UniProtKB=W5MCT6 W5MCT6 PTHR11256:SF10 BCL-2 RELATED BCL-2-RELATED PROTEIN A1 protein binding#GO:0005515;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;binding#GO:0005488 mitochondrial fusion#GO:0008053;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;organelle fusion#GO:0048284;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>A1#P00283 LEPOC|Ensembl=ENSLOCG00000013620.1|UniProtKB=W5N827 W5N827 PTHR21038:SF3 40-2-3 PROTEIN-RELATED UAP56-INTERACTING FACTOR nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011494.1|UniProtKB=W5N0G5 W5N0G5 PTHR14107:SF5 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 20 LEPOC|Ensembl=ENSLOCG00000015418.1|UniProtKB=W5NEB8 W5NEB8 PTHR10663:SF344 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007710.1|UniProtKB=W5MLV1 W5MLV1 PTHR47958:SF30 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX59-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000009570.1|UniProtKB=W5MTL3 W5MTL3 PTHR45620:SF6 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE-LIKE PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007640.1|UniProtKB=W5MLL7 W5MLL7 PTHR45626:SF17 TRANSCRIPTION TERMINATION FACTOR 2-RELATED HELICASE-LIKE TRANSCRIPTION FACTOR ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000003524.1|UniProtKB=W5M769 W5M769 PTHR19134:SF207 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE U hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011480.1|UniProtKB=W5N0E8 W5N0E8 PTHR12322:SF120 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sex differentiation#GO:0007548;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015613.1|UniProtKB=W5NF13 W5NF13 PTHR22969:SF7 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to tumor necrosis factor#GO:0034612;regulation of cellular process#GO:0050794;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>IKK#P00313;Toll receptor signaling pathway#P00054>IKKbeta#P01360;PDGF signaling pathway#P00047>Ikk#P01146;B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;Interleukin signaling pathway#P00036>Ikk#P00968;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 LEPOC|Ensembl=ENSLOCG00000016076.1|UniProtKB=W5NGP8 W5NGP8 PTHR24241:SF82 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016214.1|UniProtKB=W5NH85 W5NH85 PTHR12029:SF11 RNA METHYLTRANSFERASE METHYLTRANSFERASE TARBP1-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000004273.1|UniProtKB=W5M9Q0 W5M9Q0 PTHR32123:SF10 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 1-RELATED vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015277.1|UniProtKB=W5NDT8 W5NDT8 PTHR15953:SF0 APELIN APELIN LEPOC|Ensembl=ENSLOCG00000005549.1|UniProtKB=W5ME86 W5ME86 PTHR45713:SF8 FTP DOMAIN-CONTAINING PROTEIN SI:CH211-215K15.4 LEPOC|Ensembl=ENSLOCG00000009565.1|UniProtKB=W5MTI3 W5MTI3 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015085.1|UniProtKB=W5ND55 W5ND55 PTHR12406:SF22 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE PNPLA3 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;triglyceride catabolic process#GO:0019433;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000001746.1|UniProtKB=W5M0V6 W5M0V6 PTHR14198:SF18 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008947.1|UniProtKB=W5MR89 W5MR89 PTHR47085:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000004247.1|UniProtKB=W5M9M4 W5M9M4 PTHR13713:SF37 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-1,4-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006265.1|UniProtKB=W5MGR0 W5MGR0 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012763.1|UniProtKB=W5N4Z3 W5N4Z3 MINAR1 PTHR31530:SF2 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell population proliferation#GO:0008285;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004328.1|UniProtKB=W5M9Y4 W5M9Y4 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 male gamete generation#GO:0048232;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;sperm axoneme assembly#GO:0007288;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;spermatogenesis#GO:0007283;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cilium or flagellum-dependent cell motility#GO:0001539;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006398.1|UniProtKB=W5MH68 W5MH68 PTHR46607:SF1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 LEPOC|Ensembl=ENSLOCG00000015520.1|UniProtKB=W5NEP5 W5NEP5 PTHR46531:SF1 ZINC TRANSPORTER 6 ZINC TRANSPORTER 6 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005732.1|UniProtKB=W5MEW9 W5MEW9 PTHR24174:SF11 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 CASKIN-1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009935.1|UniProtKB=W5MUT8 W5MUT8 PTHR24078:SF568 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;unfolded protein binding#GO:0051082;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;chaperone cofactor-dependent protein refolding#GO:0051085;chaperone-mediated protein folding#GO:0061077;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein folding#GO:0006457;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;'de novo' protein folding#GO:0006458;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012276.1|UniProtKB=W5N3A2 W5N3A2 PTHR10373:SF11 TRANSCRIPTION FACTOR 7 FAMILY MEMBER LYMPHOID ENHANCER-BINDING FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;regulation of metabolic process#GO:0019222;Wnt signaling pathway#GO:0016055;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Cadherin signaling pathway#P00012>TCF/LEF#P00465 LEPOC|Ensembl=ENSLOCG00000016212.1|UniProtKB=W5NH81 W5NH81 PTHR13029:SF17 FAMILY NOT NAMED MYELIN REGULATORY FACTOR-LIKE PROTEIN sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;protein processing#GO:0016485;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;proteolysis#GO:0006508;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000007071.1|UniProtKB=W5MJK3 W5MJK3 PTHR23167:SF18 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016241.1|UniProtKB=W5NHC4 W5NHC4 PTHR10199:SF10 THROMBOSPONDIN THROMBOSPONDIN-2 regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;biological regulation#GO:0065007;negative regulation of angiogenesis#GO:0016525;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002401.1|UniProtKB=W5M361 W5M361 PTHR10924:SF27 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006154.1|UniProtKB=W5MGC5 W5MGC5 PTHR19850:SF29 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;Nicotine pharmacodynamics pathway#P06587>GNB#P06591;PI3 kinase pathway#P00048>Gbetagamma#P01188;GABA-B receptor II signaling#P05731>Gbeta#P05755;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;CCKR signaling map#P06959>Gbeta/gamma#P07197;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753 LEPOC|Ensembl=ENSLOCG00000004271.1|UniProtKB=W5M9P7 W5M9P7 PTHR25462:SF229 BONUS, ISOFORM C-RELATED TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008196.1|UniProtKB=W5MNJ2 W5MNJ2 PTHR10165:SF15 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007814.1|UniProtKB=W5MM83 W5MM83 TRAPPC9 PTHR21512:SF5 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017392.1|UniProtKB=W5NLI8 W5NLI8 PTHR24232:SF51 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009104.1|UniProtKB=W5MRU6 W5MRU6 PTHR10625:SF33 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 4 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000018051.1|UniProtKB=W5NNE3 W5NNE3 CLDN8 PTHR12002:SF24 CLAUDIN CLAUDIN-8 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000004272.1|UniProtKB=W5M9W3 W5M9W3 PTHR22829:SF1 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 2 PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of hydrolase activity#GO:0051336;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009815.1|UniProtKB=W5MUE8 W5MUE8 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007499.1|UniProtKB=W5ML44 W5ML44 PTHR18935:SF9 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000013185.1|UniProtKB=W5N6I3 W5N6I3 PTHR11417:SF2 SOMATOTROPIN,PROLACTIN SOMATOTROPIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to peptide hormone#GO:0043434;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;regulation of growth#GO:0040008;cellular response to nitrogen compound#GO:1901699;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;response to nutrient levels#GO:0031667;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to hormone#GO:0009725;response to chemical#GO:0042221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000014653.1|UniProtKB=W5NBM4 W5NBM4 PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005675.1|UniProtKB=W5MEP8 W5MEP8 PTHR24248:SF118 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR D2 LIKE ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;regulation of metal ion transport#GO:0010959;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;negative regulation of lyase activity#GO:0051350;negative regulation of cell communication#GO:0010648;regulation of monoatomic ion transmembrane transport#GO:0034765;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;response to nitrogen compound#GO:1901698;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;negative regulation of monoatomic ion transport#GO:0043271;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;negative regulation of cyclase activity#GO:0031280;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of adenylate cyclase activity#GO:0007194;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 presynapse#GO:0098793;synapse#GO:0045202;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965 LEPOC|Ensembl=ENSLOCG00000002022.1|UniProtKB=W5M1T6 W5M1T6 PTHR13586:SF2 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG A nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;non-membrane-bounded organelle assembly#GO:0140694;P-body assembly#GO:0033962;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009137.1|UniProtKB=W5MRY0 W5MRY0 PTHR12771:SF47 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012069.1|UniProtKB=W5N2J2 W5N2J2 PTHR47014:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 LEPOC|Ensembl=ENSLOCG00000007327.1|UniProtKB=W5MKJ2 W5MKJ2 PTHR19134:SF208 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE T hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012397.1|UniProtKB=W5N3R0 W5N3R0 GUF1 PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015090.1|UniProtKB=W5ND62 W5ND62 PTHR22227:SF6 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000013461.1|UniProtKB=W5N7I8 W5N7I8 PTHR48125:SF12 LP07818P1 AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED Huntington disease#P00029>N-Wasp#P00769;Cytoskeletal regulation by Rho GTPase#P00016>N-WASP#P00525 LEPOC|Ensembl=ENSLOCG00000009889.1|UniProtKB=W5MUP2 W5MUP2 PTHR24346:SF98 MAP/MICROTUBULE AFFINITY-REGULATING KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004654.1|UniProtKB=W5MB15 W5MB15 PTHR45255:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 cation binding#GO:0043169;molecular function activator activity#GO:0140677;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ATPase activator activity#GO:0001671;ion binding#GO:0043167 biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of molecular function#GO:0065009 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017524.1|UniProtKB=W5NLX0 W5NLX0 PTHR19297:SF7 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012379.1|UniProtKB=W5N3N5 W5N3N5 PTHR12659:SF4 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO-GAP DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000014358.1|UniProtKB=W5NAM2 W5NAM2 PTHR23423:SF21 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA-LIKE localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008882.1|UniProtKB=W5MR16 W5MR16 PTHR13742:SF36 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-ASSOCIATED PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of mitotic cell cycle phase transition#GO:1901991;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;cellular developmental process#GO:0048869;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;multicellular organism development#GO:0007275;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell cycle#GO:0051726;neuron development#GO:0048666;generation of neurons#GO:0048699;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 LEPOC|Ensembl=ENSLOCG00000002618.1|UniProtKB=W5M435 W5M435 PTHR10336:SF25 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;positive regulation of cell motility#GO:2000147;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;regulation of multicellular organismal process#GO:0051239;transmembrane transport#GO:0055085;regulation of cell motility#GO:2000145;calcium ion transmembrane transport#GO:0070588;positive regulation of locomotion#GO:0040017;release of sequestered calcium ion into cytosol#GO:0051209;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 VEGF signaling pathway#P00056>PLC-gamma#P01414;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;FGF signaling pathway#P00021>PLCgamma#P00638;B cell activation#P00010>PLC gamma2#P00388;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;EGF receptor signaling pathway#P00018>PLCgamma#P00556;PDGF signaling pathway#P00047>PLCgamma#P01171;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 LEPOC|Ensembl=ENSLOCG00000006785.1|UniProtKB=W5MIK6 W5MIK6 PTHR13869:SF3 MYELIN P0 RELATED SODIUM CHANNEL SUBUNIT BETA-2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002598.1|UniProtKB=W5M3U6 W5M3U6 PTHR46724:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000002572.1|UniProtKB=W5M3R2 W5M3R2 PTHR47730:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 29 SMALL INTEGRAL MEMBRANE PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000007230.1|UniProtKB=W5MK38 W5MK38 PTHR24067:SF263 UBIQUITIN-CONJUGATING ENZYME E2 UBE2G1 PROTEIN ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010689.1|UniProtKB=W5MXK5 W5MXK5 PTHR12587:SF5 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-4 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012028.1|UniProtKB=W5N2D3 W5N2D3 PTHR24055:SF162 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 10 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;JNK cascade#GO:0007254;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>Jnk#P00951;TGF-beta signaling pathway#P00052>JNK#P01284;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>JNK1#P00221;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>JNK1-3#P00545;CCKR signaling map#P06959>MAPK8-10#P07090;FGF signaling pathway#P00021>JNK1-3#P00628;FAS signaling pathway#P00020>JNK#P00615;Integrin signalling pathway#P00034>ERK#P00907;Oxidative stress response#P00046>JNK1/2#P01129;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>JNK#P00274;Toll receptor signaling pathway#P00054>JNK#P01375;B cell activation#P00010>Jnk#P00402;Parkinson disease#P00049>SAPK#P01219;T cell activation#P00053>Jnk#P01336 LEPOC|Ensembl=ENSLOCG00000012872.1|UniProtKB=W5N5D9 W5N5D9 PTHR13703:SF63 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Smad4#P01455;TGF-beta signaling pathway#P00052>Co-Smads#P01276;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819 LEPOC|Ensembl=ENSLOCG00000008812.1|UniProtKB=W5MQR3 W5MQR3 PTHR13232:SF11 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005262.1|UniProtKB=W5MD77 W5MD77 PTHR14826:SF3 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 2 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of cell motility#GO:2000145;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;ameboidal-type cell migration#GO:0001667;cellular component organization#GO:0016043;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;hippo signaling#GO:0035329;angiogenesis#GO:0001525;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;tight junction#GO:0070160;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000010945.1|UniProtKB=W5MYG8 W5MYG8 PTHR24361:SF414 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEKK1#P00208;Toll receptor signaling pathway#P00054>MEKK1#P01357;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Apoptosis signaling pathway#P00006>MEKK1#P00291;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Ras Pathway#P04393>MEKK1/4#P04543;T cell activation#P00053>MEKK#P01297 LEPOC|Ensembl=ENSLOCG00000009399.1|UniProtKB=W5MSV9 W5MSV9 PTHR23354:SF69 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009006.1|UniProtKB=W5MRG8 W5MRG8 PTHR24083:SF47 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011000.1|UniProtKB=W5MYN6 W5MYN6 PTHR19269:SF46 TROPOMYOSIN TROPOMYOSIN BETA CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000008477.1|UniProtKB=W5MPL0 W5MPL0 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 LEPOC|Ensembl=ENSLOCG00000012210.1|UniProtKB=W5N314 W5N314 PTHR12196:SF2 DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN DIPHTHINE--AMMONIA LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000015888.1|UniProtKB=W5NG10 W5NG10 PTHR11133:SF22 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012348.1|UniProtKB=W5N3J2 W5N3J2 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013492.1|UniProtKB=W5N7M4 W5N7M4 PTHR15852:SF49 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG LEPOC|Ensembl=ENSLOCG00000003965.1|UniProtKB=W5M8Q0 W5M8Q0 PTHR12461:SF106 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012353.1|UniProtKB=W5N3K3 W5N3K3 PTHR11359:SF3 AMP DEAMINASE AMP DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004871.1|UniProtKB=W5MBV1 W5MBV1 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000976.1|UniProtKB=W5LY91 W5LY91 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004532.1|UniProtKB=W5MAL2 W5MAL2 PTHR10411:SF3 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p38 MAPK pathway#P05918>GADD45#P06044;p53 pathway#P00059>GADD45#G01575;PI3 kinase pathway#P00048>GADD45#G01544;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000005862.1|UniProtKB=W5MFC0 W5MFC0 ACVR1 PTHR23255:SF69 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;phosphate-containing compound metabolic process#GO:0006796;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;system development#GO:0048731;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000009003.1|UniProtKB=W5MRF9 W5MRF9 PTHR10183:SF382 CALPAIN CALPAIN-15 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000018143.1|UniProtKB=W5NNN5 W5NNN5 PTHR12002:SF213 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000008055.1|UniProtKB=W5MN23 W5MN23 PTHR23343:SF4 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000014589.1|UniProtKB=W5NBE7 W5NBE7 PTHR12125:SF12 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 6 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 carbohydrate derivative metabolic process#GO:1901135;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016904.1|UniProtKB=W5NJU0 W5NJU0 SENP6 PTHR46896:SF1 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 6 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of chromosome organization#GO:0033044;regulation of microtubule-based process#GO:0032886;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;nitrogen compound metabolic process#GO:0006807;regulation of organelle assembly#GO:1902115;protein modification by small protein removal#GO:0070646;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017937.1|UniProtKB=W5NN31 W5NN31 G0S2 PTHR15570:SF2 G0/G1 SWITCH PROTEIN 2 G0_G1 SWITCH PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000001569.1|UniProtKB=W5M086 W5M086 PTHR23049:SF36 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 10 cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016618.1|UniProtKB=W5NIR9 W5NIR9 PTHR23333:SF16 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2A protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;membrane organization#GO:0061024;protein catabolic process#GO:0030163;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;membrane assembly#GO:0071709;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear membrane organization#GO:0071763;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;nuclear envelope organization#GO:0006998;autophagy#GO:0006914 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008688.1|UniProtKB=W5MQA7 W5MQA7 PTHR23507:SF9 ZGC:174356 LYSOSOMAL PROTON-COUPLED STEROID CONJUGATE AND BILE ACID SYMPORTER SLC46A3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008969.1|UniProtKB=W5MRC9 W5MRC9 PTHR11751:SF308 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 1 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005595.1|UniProtKB=W5MEE6 W5MEE6 PTHR14742:SF0 RIBONUCLEASE P SUBUNIT P21 RIBONUCLEASE P PROTEIN SUBUNIT P21 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012187.1|UniProtKB=W5N2Y1 W5N2Y1 PTHR11347:SF115 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;retina development in camera-type eye#GO:0060041;eye development#GO:0001654;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 LEPOC|Ensembl=ENSLOCG00000002190.1|UniProtKB=W5M2E1 W5M2E1 PTHR13328:SF4 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A LEPOC|Ensembl=ENSLOCG00000014399.1|UniProtKB=W5NAR5 W5NAR5 PTHR21192:SF2 NUCLEAR PROTEIN E3-3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3 LEPOC|Ensembl=ENSLOCG00000008184.1|UniProtKB=W5MNH7 W5MNH7 PTHR13439:SF49 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 4-B lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010760.1|UniProtKB=W5MXS2 W5MXS2 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007662.1|UniProtKB=W5MLP0 W5MLP0 PTHR10908:SF5 SEROTONIN N-ACETYLTRANSFERASE ARYLALKYLAMINE N-ACETYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 response to stimulus#GO:0050896;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;response to abiotic stimulus#GO:0009628;rhythmic process#GO:0048511;response to radiation#GO:0009314 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000014241.1|UniProtKB=W5NA77 W5NA77 PTHR15422:SF21 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015528.1|UniProtKB=W5NER5 W5NER5 PTHR11915:SF226 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011258.1|UniProtKB=W5MZM6 W5MZM6 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000016630.1|UniProtKB=W5NIT3 W5NIT3 PTHR43782:SF2 ARGINASE ARGINASE-1 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;arginine metabolic process#GO:0006525;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016851.1|UniProtKB=W5NJM1 W5NJM1 PTHR45740:SF4 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003173.1|UniProtKB=W5M5U9 W5M5U9 PTHR24416:SF125 TYROSINE-PROTEIN KINASE RECEPTOR ANGIOPOIETIN-1 RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;epithelial cell proliferation#GO:0050673;vasculature development#GO:0001944;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Tie2#P00247 LEPOC|Ensembl=ENSLOCG00000002789.1|UniProtKB=W5M4H2 W5M4H2 PTHR12952:SF0 SYS1 PROTEIN SYS1 HOMOLOG protein localization to plasma membrane#GO:0072659;Golgi to endosome transport#GO:0006895;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005762.1|UniProtKB=W5MF00 W5MF00 PTHR21502:SF2 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000013525.1|UniProtKB=W5N7R8 W5N7R8 PTHR23113:SF230 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR-LIKE 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008722.1|UniProtKB=W5MQG1 W5MQG1 PTHR21569:SF1 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007547.1|UniProtKB=W5MLA0 W5MLA0 PTHR43829:SF13 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-10 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;amide transmembrane transporter activity#GO:0042887;channel activity#GO:0015267;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;water transport#GO:0006833;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;fluid transport#GO:0042044 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010128.1|UniProtKB=W5MVK0 W5MVK0 PTHR24351:SF198 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C ETA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018070.1|UniProtKB=W5NNG2 W5NNG2 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006804.1|UniProtKB=W5MIM6 W5MIM6 PTHR24412:SF418 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014630.1|UniProtKB=W5NBJ8 W5NBJ8 PTHR23351:SF3 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN FOSB sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06666;Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06878;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709 LEPOC|Ensembl=ENSLOCG00000002986.1|UniProtKB=W5M563 W5M563 PTHR24208:SF121 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;central nervous system neuron differentiation#GO:0021953;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;forebrain development#GO:0030900;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008927.1|UniProtKB=W5MR64 W5MR64 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 cation binding#GO:0043169;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;iron ion binding#GO:0005506;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003482.1|UniProtKB=W5M6X0 W5M6X0 PTHR22923:SF50 CEREBELLIN-RELATED CEREBELLIN-2 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005934.1|UniProtKB=W5MFM5 W5MFM5 PTHR19433:SF137 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013147.1|UniProtKB=W5N6D8 W5N6D8 PTHR43448:SF2 PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 acyltransferase#PC00042 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 LEPOC|Ensembl=ENSLOCG00000010388.1|UniProtKB=W5MWI6 W5MWI6 PTHR45945:SF1 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING 12 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000007273.1|UniProtKB=W5MK97 W5MK97 PTHR10921:SF2 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;establishment or maintenance of cell polarity#GO:0007163;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;transport#GO:0006810;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component assembly#GO:0022607;establishment of chromosome localization#GO:0051303;vesicle localization#GO:0051648;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;establishment of spindle localization#GO:0051293;transport along microtubule#GO:0010970;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;centrosome localization#GO:0051642;protein polymerization#GO:0051258;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;chromosome localization#GO:0050000;cell migration#GO:0016477;microtubule nucleation#GO:0007020;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000008157.1|UniProtKB=W5MNE8 W5MNE8 PTHR11945:SF804 MADS BOX PROTEIN MYOCYTE ENHANCER FACTOR 2D MEF2D cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 MADS box transcription factor#PC00250 LEPOC|Ensembl=ENSLOCG00000002383.1|UniProtKB=W5M346 W5M346 PTHR24416:SF297 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;collagen binding#GO:0005518;molecular transducer activity#GO:0060089;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002180.1|UniProtKB=W5M2N3 W5M2N3 PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000007674.1|UniProtKB=W5MLQ5 W5MLQ5 PTHR12112:SF47 BNIP - RELATED EXOPOLYPHOSPHATASE PRUNE1 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;exopolyphosphatase activity#GO:0004309;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004627.1|UniProtKB=W5MAY5 W5MAY5 PTHR14948:SF1 NG5 TRAFFICKING REGULATOR OF GLUT4 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001353.1|UniProtKB=W5LZL8 W5LZL8 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 DNA REPAIR PROTEIN REV1 DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013108.1|UniProtKB=W5N690 W5N690 PTHR11562:SF27 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A4-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;response to stimulus#GO:0050896;metal ion transport#GO:0030001;response to chemical#GO:0042221;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004309.1|UniProtKB=W5M9T8 W5M9T8 OLFML1 PTHR23192:SF13 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001934.1|UniProtKB=W5M1H9 W5M1H9 PTHR31548:SF4 CLARIN CLARIN-1 multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;sensory perception of sound#GO:0007605;system process#GO:0003008 LEPOC|Ensembl=ENSLOCG00000016013.1|UniProtKB=W5NGG6 W5NGG6 PTHR10316:SF27 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 2 SMAD binding#GO:0046332;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;signaling receptor complex adaptor activity#GO:0030159;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;regulation of biological process#GO:0050789;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;receptor clustering#GO:0043113;signaling#GO:0023052 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;anchoring junction#GO:0070161;neuron projection#GO:0043005;cell-cell junction#GO:0005911;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004811.1|UniProtKB=W5MBL7 W5MBL7 PTHR11945:SF145 MADS BOX PROTEIN MYOCYTE ENHANCER FACTOR 2B-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 LEPOC|Ensembl=ENSLOCG00000018368.1|UniProtKB=W5NPB0 W5NPB0 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008057.1|UniProtKB=W5MN37 W5MN37 OSBP2 PTHR10972:SF194 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002626.1|UniProtKB=W5M3Y3 W5M3Y3 PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001537.1|UniProtKB=W5M047 W5M047 PTHR11214:SF368 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000016792.1|UniProtKB=W5NJE6 W5NJE6 PTHR10157:SF41 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 2 HOMOLOG cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 organic hydroxy compound metabolic process#GO:1901615;cellular aromatic compound metabolic process#GO:0006725;amine metabolic process#GO:0009308;alcohol biosynthetic process#GO:0046165;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;catecholamine metabolic process#GO:0006584;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;extracellular region#GO:0005576;secretory granule#GO:0030141;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000001252.1|UniProtKB=W5LZ62 W5LZ62 DDRGK1 PTHR48176:SF1 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 LEPOC|Ensembl=ENSLOCG00000004649.1|UniProtKB=W5MB10 W5MB10 PTHR12628:SF12 POLYCOMB-LIKE TRANSCRIPTION FACTOR METAL-RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR 2 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014877.1|UniProtKB=W5NCG3 W5NCG3 PTHR10083:SF376 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013332.1|UniProtKB=W5N719 W5N719 PTHR34341:SF1 TRANSMEMBRANE PROTEIN 107 TRANSMEMBRANE PROTEIN 107 cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000010334.1|UniProtKB=W5MWA1 W5MWA1 PTHR10460:SF26 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;SH3 domain binding#GO:0017124;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell motility#GO:0048870;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477 cytoplasm#GO:0005737;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;actin-based cell projection#GO:0098858;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002582.1|UniProtKB=W5M3S8 W5M3S8 PTHR24230:SF64 G-PROTEIN COUPLED RECEPTOR KISS1 RECEPTOR A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006157.1|UniProtKB=W5MGD0 W5MGD0 PTHR24078:SF519 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 13 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;chaperone cofactor-dependent protein refolding#GO:0051085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004937.1|UniProtKB=W5MC33 W5MC33 PTHR15960:SF2 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000002200.1|UniProtKB=W5M2F1 W5M2F1 PTHR47147:SF1 SYNCOILIN SYNCOILIN LEPOC|Ensembl=ENSLOCG00000002959.1|UniProtKB=W5M531 W5M531 PTHR16074:SF4 BARDET-BIEDL SYNDROME 7 PROTEIN BARDET-BIEDL SYNDROME 7 PROTEIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000016451.1|UniProtKB=W5NI61 W5NI61 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008560.1|UniProtKB=W5MPV4 W5MPV4 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000015564.1|UniProtKB=W5NEV2 W5NEV2 PTHR24027:SF431 CADHERIN-23 CADHERIN-RELATED FAMILY MEMBER 5-LIKE ISOFORM X1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000003585.1|UniProtKB=W5M796 W5M796 PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B LEPOC|Ensembl=ENSLOCG00000005793.1|UniProtKB=W5MF39 W5MF39 PTHR47137:SF1 ERMIN ERMIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;morphogenesis of a branching structure#GO:0001763 somatodendritic compartment#GO:0036477;filopodium#GO:0030175;extracellular region#GO:0005576;neuronal cell body#GO:0043025;actin-based cell projection#GO:0098858;extracellular space#GO:0005615;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell body#GO:0044297;neuron projection#GO:0043005;main axon#GO:0044304;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000004587.1|UniProtKB=W5MAU4 W5MAU4 PTHR18945:SF53 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3B monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 LEPOC|Ensembl=ENSLOCG00000012325.1|UniProtKB=W5N3F6 W5N3F6 PTHR23323:SF26 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle localization#GO:0051640;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vacuole organization#GO:0007033;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;organelle fusion#GO:0048284;secretion by cell#GO:0032940 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000000578.1|UniProtKB=W5LWY2 W5LWY2 PTHR45615:SF13 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIA microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000006514.1|UniProtKB=W5MHK5 W5MHK5 PTHR36872:SF1 GENE 5901-RELATED GENE 5901-RELATED LEPOC|Ensembl=ENSLOCG00000004480.1|UniProtKB=W5MAE3 W5MAE3 PTHR10877:SF197 POLYCYSTIN FAMILY MEMBER POLYCYSTIC KIDNEY DISEASE PROTEIN 1-LIKE 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002668.1|UniProtKB=W5M440 W5M440 PTHR13986:SF3 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT CARTILAGE-ASSOCIATED PROTEIN collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;binding#GO:0005488 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organic cyclic compound metabolic process#GO:1901360;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;nitrogen compound metabolic process#GO:0006807;supramolecular fiber organization#GO:0097435;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008216.1|UniProtKB=W5MNM0 W5MNM0 VWA3A PTHR46478:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A LEPOC|Ensembl=ENSLOCG00000008250.1|UniProtKB=W5MNQ9 W5MNQ9 PTHR45845:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PLECKSTRIN HOMOLOGY DOMAIN CONTAINING, FAMILY G (WITH RHOGEF DOMAIN) MEMBER 4 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015470.1|UniProtKB=W5NEI1 W5NEI1 PTHR11937:SF389 ACTIN ACTIN, ALPHA 1B, SKELETAL MUSCLE intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000007371.1|UniProtKB=W5MKM8 W5MKM8 CIR1 PTHR13151:SF2 CBF1 INTERACTING COREPRESSOR CIR COREPRESSOR INTERACTING WITH RBPJ 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Notch signaling pathway#P00045>CoR#P01112 LEPOC|Ensembl=ENSLOCG00000005575.1|UniProtKB=W5MEB9 W5MEB9 F2RL1 PTHR24232:SF21 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001972.1|UniProtKB=W5M1P0 W5M1P0 PTHR11347:SF135 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4C hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000016889.1|UniProtKB=W5NJR9 W5NJR9 PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009097.1|UniProtKB=W5MRT6 W5MRT6 PTHR10921:SF2 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;establishment or maintenance of cell polarity#GO:0007163;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;transport#GO:0006810;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component assembly#GO:0022607;establishment of chromosome localization#GO:0051303;vesicle localization#GO:0051648;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;establishment of spindle localization#GO:0051293;transport along microtubule#GO:0010970;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;centrosome localization#GO:0051642;protein polymerization#GO:0051258;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;chromosome localization#GO:0050000;cell migration#GO:0016477;microtubule nucleation#GO:0007020;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000000725.1|UniProtKB=W5LXF0 W5LXF0 PTHR10812:SF13 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-EPSILON sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013565.1|UniProtKB=W5N7X2 W5N7X2 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017725.1|UniProtKB=W5NMH0 W5NMH0 PTHR13675:SF1 LYR MOTIF-CONTAINING PROTEIN 2 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex II assembly#GO:0034553;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017965.1|UniProtKB=W5NN59 W5NN59 GPR150 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 150-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008747.1|UniProtKB=W5MQJ0 W5MQJ0 PTHR45937:SF1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007608.1|UniProtKB=W5MLH0 W5MLH0 PTHR24327:SF33 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016345.1|UniProtKB=W5NHS5 W5NHS5 PTHR15356:SF0 NEUROTENSIN/NEUROMEDIN N NEUROTENSIN_NEUROMEDIN N LEPOC|Ensembl=ENSLOCG00000008915.1|UniProtKB=W5MR54 W5MR54 PTHR43435:SF4 RIBULOKINASE FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;carbohydrate phosphorylation#GO:0046835;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849;Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077 LEPOC|Ensembl=ENSLOCG00000005671.1|UniProtKB=W5MEP2 W5MEP2 PTHR10177:SF71 CYCLINS G1_S-SPECIFIC CYCLIN-E1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489;p53 pathway#P00059>Cyclin E#P04610;p53 pathway feedback loops 2#P04398>cyclin E#P04664;Cell cycle#P00013>Cyclin E#P00483 LEPOC|Ensembl=ENSLOCG00000005870.1|UniProtKB=W5MFD1 W5MFD1 PTHR23162:SF8 OUTER DENSE FIBER OF SPERM TAILS 2 OUTER DENSE FIBER PROTEIN 2 regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle assembly#GO:1902115;regulation of organelle organization#GO:0033043;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007166.1|UniProtKB=W5MK05 W5MK05 PTHR24023:SF1023 COLLAGEN ALPHA COLLAGEN ALPHA-3(V) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011668.1|UniProtKB=W5N140 W5N140 PTHR12895:SF9 DYMECLIN DYMECLIN endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016279.1|UniProtKB=W5NHH3 W5NHH3 PTHR12081:SF25 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000006104.1|UniProtKB=W5MG65 W5MG65 PTHR12638:SF0 PROTEIN MAGO NASHI HOMOLOG MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017503.1|UniProtKB=W5NLU9 W5NLU9 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004083.1|UniProtKB=W5M929 W5M929 PTHR10857:SF6 COPINE COPINE-7 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000004771.1|UniProtKB=W5MBG4 W5MBG4 PTHR47266:SF28 ENDONUCLEASE-RELATED TRANSPOSON TF2-1 POLYPROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000011871.1|UniProtKB=W5N1T7 W5N1T7 PTHR13820:SF4 SYNUCLEIN BETA-SYNUCLEIN cation binding#GO:0043169;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cell-cell signaling#GO:0007267;signaling#GO:0023052;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;cell body#GO:0044297;distal axon#GO:0150034;cell projection#GO:0042995 membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>beta-Synuclein#P01217 LEPOC|Ensembl=ENSLOCG00000005335.1|UniProtKB=W5MDH0 W5MDH0 PTHR13509:SF3 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;post-translational protein targeting to membrane, translocation#GO:0031204;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cellular anatomical entity#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009590.1|UniProtKB=W5MTM2 W5MTM2 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002487.1|UniProtKB=W5M3G5 W5M3G5 PTHR45787:SF8 LD11652P LIM DOMAIN ONLY 4-RELATED LEPOC|Ensembl=ENSLOCG00000003152.1|UniProtKB=W5M5R1 W5M5R1 PTHR13610:SF5 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ADENINE NUCLEOTIDE TRANSLOCASE LYSINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;peptidyl-amino acid modification#GO:0018193;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;positive regulation of transporter activity#GO:0032411;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006608.1|UniProtKB=W5MHX6 W5MHX6 TSFM PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005046.1|UniProtKB=W5MCG4 W5MCG4 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;response to stress#GO:0006950;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004251.1|UniProtKB=W5M9M1 W5M9M1 PTHR12326:SF10 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3 LEPOC|Ensembl=ENSLOCG00000000439.1|UniProtKB=W5LWH2 W5LWH2 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011939.1|UniProtKB=W5N224 W5N224 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 LEPOC|Ensembl=ENSLOCG00000006816.1|UniProtKB=W5MIQ0 W5MIQ0 PTHR24204:SF4 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;cell projection morphogenesis#GO:0048858;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#P06791;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06896;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06682 LEPOC|Ensembl=ENSLOCG00000011448.1|UniProtKB=W5N0D2 W5N0D2 PTHR24222:SF76 ABC TRANSPORTER B FAMILY MYCOBACTIN IMPORT ATP-BINDING_PERMEASE PROTEIN IRTB transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012951.1|UniProtKB=W5N5P4 W5N5P4 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000006632.1|UniProtKB=W5MI00 W5MI00 PTHR15276:SF0 H4 D10S170 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000014107.1|UniProtKB=W5N9S6 W5N9S6 PTHR10846:SF21 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002324.1|UniProtKB=W5M2W8 W5M2W8 PTHR16209:SF5 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN-BINDING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011530.1|UniProtKB=W5N0K8 W5N0K8 PTHR21637:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD20 regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of phosphorylation#GO:0042327;regulation of phosphate metabolic process#GO:0019220;positive regulation of metabolic process#GO:0009893;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;positive regulation of cellular metabolic process#GO:0031325;biological regulation#GO:0065007;positive regulation of phosphorus metabolic process#GO:0010562;regulation of phosphorylation#GO:0042325;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001727.1|UniProtKB=W5M0T5 W5M0T5 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012145.1|UniProtKB=W5N2T2 W5N2T2 PTHR45776:SF5 MIP04163P TRANSCRIPTION FACTOR EB sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017648.1|UniProtKB=W5NM94 W5NM94 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000271.1|UniProtKB=W5LVY7 W5LVY7 PTHR24393:SF5 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM16 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005348.1|UniProtKB=W5MDI3 W5MDI3 PTHR15950:SF22 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN VESTIGIAL LIKE 2B transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000013216.1|UniProtKB=W5N6M1 W5N6M1 DNASE1L3 PTHR11371:SF32 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE GAMMA hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000002100.1|UniProtKB=W5M224 W5M224 PTHR31898:SF1 TRANSMEMBRANE PROTEIN 136 TLC DOMAIN-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000020986.1|UniProtKB=Q8HQM9 Q8HQM9 ATP 8 PTHR39937:SF1 ATP SYNTHASE PROTEIN 8 ATP SYNTHASE PROTEIN 8 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001190.1|UniProtKB=W5LYY7 W5LYY7 PTHR12773:SF0 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;tRNA processing#GO:0008033;RNA processing#GO:0006396;protein modification process#GO:0036211;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 LEPOC|Ensembl=ENSLOCG00000008187.1|UniProtKB=W5MNI1 W5MNI1 PTHR18945:SF29 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT BETA inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;chloride transmembrane transporter activity#GO:0015108;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018336.1|UniProtKB=W5NP78 W5NP78 PTHR24247:SF193 5-HYDROXYTRYPTAMINE RECEPTOR BETA-2 ADRENERGIC RECEPTOR-LIKE cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008796.1|UniProtKB=W5MQP5 W5MQP5 PTHR15917:SF0 FAMILY NOT NAMED PROTEIN LARGEN positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of anatomical structure size#GO:0090066;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of cell size#GO:0008361;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000016446.1|UniProtKB=W5NI52 W5NI52 PTHR12547:SF174 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L2 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002301.1|UniProtKB=W5M2T7 W5M2T7 NUBP2 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018012.1|UniProtKB=W5NNA4 W5NNA4 PTHR11984:SF26 CONNEXIN GAP JUNCTION BETA-7 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000017162.1|UniProtKB=W5NKQ5 W5NKQ5 PTHR11767:SF55 INWARD RECTIFIER POTASSIUM CHANNEL KIR6.3 PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003280.1|UniProtKB=W5M664 W5M664 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004201.1|UniProtKB=W5M9H5 W5M9H5 PTHR46877:SF18 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017102.1|UniProtKB=W5NKH4 W5NKH4 PTHR42884:SF23 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000009927.1|UniProtKB=W5MUT1 W5MUT1 PTHR11482:SF7 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 1 carboxy-lyase activity#GO:0016831;molecular function activator activity#GO:0140677;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;lyase activity#GO:0016829;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;biogenic amine metabolic process#GO:0006576;negative regulation of protein catabolic process#GO:0042177;regulation of localization#GO:0032879;regulation of protein catabolic process#GO:0042176;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amine metabolic process#GO:0009308;regulation of transmembrane transport#GO:0034762;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular biosynthetic process#GO:0044249;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;negative regulation of nitrogen compound metabolic process#GO:0051172;polyamine metabolic process#GO:0006595;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 LEPOC|Ensembl=ENSLOCG00000013755.1|UniProtKB=W5N8K5 W5N8K5 PTHR11486:SF67 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 11 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of sodium ion transport#GO:0002028;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of metal ion transport#GO:0010959;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular developmental process#GO:0048869;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000004713.1|UniProtKB=W5MB87 W5MB87 PTHR11937:SF526 ACTIN ACTIN, CYTOPLASMIC 1-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000011366.1|UniProtKB=W5N028 W5N028 PTHR22775:SF3 SORTING NEXIN SORTING NEXIN-13 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS-PX1#P00706 LEPOC|Ensembl=ENSLOCG00000014538.1|UniProtKB=W5NB84 W5NB84 PTHR24359:SF34 SERINE/THREONINE-PROTEIN KINASE SBK1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017229.1|UniProtKB=W5NL01 W5NL01 PTHR24064:SF462 SOLUTE CARRIER FAMILY 22 MEMBER SI:DKEY-190L8.2 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014996.1|UniProtKB=W5NCV7 W5NCV7 PTHR12974:SF30 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5D adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000014227.1|UniProtKB=W5NA62 W5NA62 PTHR11769:SF6 HYALURONIDASE HYALURONIDASE-2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015379.1|UniProtKB=W5NE69 W5NE69 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 axoneme#GO:0005930;ciliary base#GO:0097546;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016525.1|UniProtKB=W5NIF2 W5NIF2 UPK3A PTHR15446:SF17 UROPLAKIN III UROPLAKIN-3A localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;water transport#GO:0006833;establishment of localization#GO:0051234;transport#GO:0006810;nitrogen compound transport#GO:0071705;fluid transport#GO:0042044 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016179.1|UniProtKB=W5NH33 W5NH33 PTHR21625:SF1 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX PROTEIN 1 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000010067.1|UniProtKB=W5MVA8 W5MVA8 PTHR24055:SF172 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 9 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;JNK cascade#GO:0007254;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>Jnk#P00951;TGF-beta signaling pathway#P00052>JNK#P01284;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>JNK1-3#P00545;CCKR signaling map#P06959>MAPK8-10#P07090;FGF signaling pathway#P00021>JNK1-3#P00628;FAS signaling pathway#P00020>JNK#P00615;Oxidative stress response#P00046>JNK1/2#P01129;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Huntington disease#P00029>JNK-2#P00799;Apoptosis signaling pathway#P00006>JNK#P00274;Toll receptor signaling pathway#P00054>JNK#P01375;B cell activation#P00010>Jnk#P00402;Parkinson disease#P00049>SAPK#P01219;T cell activation#P00053>Jnk#P01336;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847 LEPOC|Ensembl=ENSLOCG00000012033.1|UniProtKB=W5N2E2 W5N2E2 PTHR24133:SF58 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008410.1|UniProtKB=W5MPD4 W5MPD4 PTHR10663:SF320 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-3 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002655.1|UniProtKB=W5M449 W5M449 PTHR23335:SF9 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017555.1|UniProtKB=W5NM01 W5NM01 PTHR46473:SF10 GH08155P LD45603P-RELATED LEPOC|Ensembl=ENSLOCG00000003674.1|UniProtKB=W5M7K8 W5M7K8 PTHR10434:SF11 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000011882.1|UniProtKB=W5N1U9 W5N1U9 PTHR37476:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 LEPOC|Ensembl=ENSLOCG00000003855.1|UniProtKB=W5M893 W5M893 PTHR23037:SF36 CYTOKINE RECEPTOR INTERLEUKIN 21 RECEPTOR, TANDEM DUPLICATE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005724.1|UniProtKB=W5MEU8 W5MEU8 USP35 PTHR24006:SF660 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003675.1|UniProtKB=W5M7K4 W5M7K4 PTHR16465:SF0 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018152.1|UniProtKB=W5NNP4 W5NNP4 PTHR46048:SF6 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007924.1|UniProtKB=W5MMM7 W5MMM7 PTHR11139:SF69 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE ATR transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;telomere organization#GO:0032200;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;cell cycle checkpoint signaling#GO:0000075;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>ATM#P04669;p53 pathway#P00059>ATM/ATR#P01481 LEPOC|Ensembl=ENSLOCG00000004078.1|UniProtKB=W5M912 W5M912 PTHR15119:SF0 SECRETOGRANIN II SECRETOGRANIN-2 Gonadotropin-releasing hormone receptor pathway#P06664>Scg2#G06880 LEPOC|Ensembl=ENSLOCG00000003505.1|UniProtKB=W5M702 W5M702 PTHR11851:SF49 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008506.1|UniProtKB=W5MPP5 W5MPP5 PTHR45721:SF3 LAMIN DM0-RELATED LAMIN-B1 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;nuclear migration#GO:0007097;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;establishment of organelle localization#GO:0051656;negative regulation of cellular process#GO:0048523;localization within membrane#GO:0051668;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular macromolecule localization#GO:0070727;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;chromatin organization#GO:0006325;intracellular transport#GO:0046907;nuclear envelope organization#GO:0006998;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;protein-containing complex localization#GO:0031503 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear periphery#GO:0034399;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 FAS signaling pathway#P00020>Nuclear Lamin#P00616 LEPOC|Ensembl=ENSLOCG00000001828.1|UniProtKB=W5M166 W5M166 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of response to stress#GO:0080134;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;cellular response to stress#GO:0033554;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015572.1|UniProtKB=W5NEW6 W5NEW6 TRAF5 PTHR10131:SF83 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 5 enzyme binding#GO:0019899;protein binding#GO:0005515;tumor necrosis factor receptor binding#GO:0005164;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of cell communication#GO:0010646;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of NF-kappaB transcription factor activity#GO:0051092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011891.1|UniProtKB=W5N1W0 W5N1W0 PTHR28643:SF1 SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG transcription coactivator activity#GO:0003713;nuclear receptor coactivator activity#GO:0030374;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;double-strand break repair#GO:0006302;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;recombinational repair#GO:0000725;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016130.1|UniProtKB=W5NGX0 W5NGX0 PTHR10682:SF6 POLY A POLYMERASE POLY(A) POLYMERASE GAMMA adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007233.1|UniProtKB=W5MK43 W5MK43 PTHR13651:SF0 PROTEIN ABITRAM PROTEIN ABITRAM LEPOC|Ensembl=ENSLOCG00000000409.1|UniProtKB=W5LWD7 W5LWD7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006053.1|UniProtKB=W5MG48 W5MG48 PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002098.1|UniProtKB=W5M221 W5M221 PTHR16719:SF0 CYTOCHROME C OXIDASE COPPER CHAPERONE CYTOCHROME C OXIDASE COPPER CHAPERONE chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000591.1|UniProtKB=W5LWZ6 W5LWZ6 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002131.1|UniProtKB=W5M270 W5M270 PTHR24103:SF695 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-18P12.4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005059.1|UniProtKB=W5MCI2 W5MCI2 SIM2 PTHR23043:SF19 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008975.1|UniProtKB=W5MRC8 W5MRC8 PTHR24291:SF6 CYTOCHROME P450 FAMILY 4 STEROL 26-HYDROXYLASE, MITOCHONDRIAL steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;cholesterol metabolic process#GO:0008203;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 LEPOC|Ensembl=ENSLOCG00000002376.1|UniProtKB=W5M345 W5M345 BET1L PTHR12791:SF37 GOLGI SNARE BET1-RELATED BET1-LIKE PROTEIN molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 endosomal transport#GO:0016197;cellular localization#GO:0051641;transport#GO:0006810;regulation of localization#GO:0032879;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;regulation of vesicle-mediated transport#GO:0060627;retrograde transport, endosome to Golgi#GO:0042147;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000000513.1|UniProtKB=W5LWQ8 W5LWQ8 PTHR14186:SF20 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED CYSTEINE-RICH MOTOR NEURON 1 PROTEIN-LIKE regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000008294.1|UniProtKB=W5MNW7 W5MNW7 PTHR46518:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014476.1|UniProtKB=W5NB10 W5NB10 PTHR23248:SF57 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013909.1|UniProtKB=W5N957 W5N957 PTHR10627:SF67 SCP160 HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000955.1|UniProtKB=W5LY61 W5LY61 PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016979.1|UniProtKB=W5NK30 W5NK30 LAMA4 PTHR10574:SF409 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;neuron differentiation#GO:0030182;vasculature development#GO:0001944;visual system development#GO:0150063;sensory system development#GO:0048880;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;sensory organ development#GO:0007423 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000002477.1|UniProtKB=W5M3E6 W5M3E6 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005770.1|UniProtKB=W5MF18 W5MF18 PTHR10337:SF5 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 2 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Shc#P00554;Angiogenesis#P00005>Sck#P00202;PDGF signaling pathway#P00047>Shc#P01175;VEGF signaling pathway#P00056>Sck#P01424 LEPOC|Ensembl=ENSLOCG00000004068.1|UniProtKB=W5M913 W5M913 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007275.1|UniProtKB=W5MKA1 W5MKA1 PTHR14247:SF11 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3A positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein modification process#GO:0031401;positive regulation of cellular process#GO:0048522;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000011766.1|UniProtKB=W5N1F9 W5N1F9 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001324.1|UniProtKB=W5LZE9 W5LZE9 PTHR36465:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010728.1|UniProtKB=W5MXN1 W5MXN1 PTHR12416:SF2 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000016176.1|UniProtKB=W5NH24 W5NH24 PTHR11419:SF0 INTERFERON GAMMA INTERFERON GAMMA cytokine#PC00083;interferon superfamily#PC00127 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>INFgamma#P00878;Interferon-gamma signaling pathway#P00035>Interferongamma#P00954 LEPOC|Ensembl=ENSLOCG00000009479.1|UniProtKB=W5MT79 W5MT79 PTHR23282:SF116 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000003127.1|UniProtKB=W5M5P1 W5M5P1 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000891.1|UniProtKB=W5LXY8 W5LXY8 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000010943.1|UniProtKB=W5MYG3 W5MYG3 PTHR45945:SF2 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING 14 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;cell division#GO:0051301;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 LEPOC|Ensembl=ENSLOCG00000011233.1|UniProtKB=W5MZJ2 W5MZJ2 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000003305.1|UniProtKB=W5M696 W5M696 PTHR11848:SF241 TGF-BETA FAMILY ANTI-DORSALIZING MORPHOTIC PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000012525.1|UniProtKB=W5N472 W5N472 PTHR11814:SF55 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002528.1|UniProtKB=W5M3L0 W5M3L0 PTHR14096:SF59 APOLIPOPROTEIN L APOLIPOPROTEIN L, 1 ISOFORM X1 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000013918.1|UniProtKB=W5N948 W5N948 TSC22D3 PTHR12348:SF24 TSC22 TSC22 DOMAIN FAMILY PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000017957.1|UniProtKB=W5NN51 W5NN51 PTHR11829:SF209 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015669.1|UniProtKB=W5NF77 W5NF77 PTHR12247:SF62 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015419.1|UniProtKB=W5NEB9 W5NEB9 PTHR45673:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT GAMMA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;calcineurin-mediated signaling#GO:0097720;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 T cell activation#P00053>Calcineurin#P01315;B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446 LEPOC|Ensembl=ENSLOCG00000007679.1|UniProtKB=W5MLR1 W5MLR1 PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 LEPOC|Ensembl=ENSLOCG00000009425.1|UniProtKB=W5MSZ3 W5MSZ3 PTHR12958:SF5 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM2 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000005900.1|UniProtKB=W5MFH1 W5MFH1 PTHR14339:SF10 VASCULIN VASCULIN-LIKE PROTEIN 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000909.1|UniProtKB=W5LY11 W5LY11 GTF3C1 PTHR15180:SF1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;rRNA transcription#GO:0009303;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000012409.1|UniProtKB=W5N3S0 W5N3S0 PTHR13703:SF42 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;activin receptor signaling pathway#GO:0032924;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 LEPOC|Ensembl=ENSLOCG00000003119.1|UniProtKB=W5M5N0 W5M5N0 LONP1 PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015783.1|UniProtKB=W5NFM0 W5NFM0 PTHR11220:SF69 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012790.1|UniProtKB=W5N538 W5N538 PTHR46652:SF8 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE RICH REPEAT CONTAINING 23 LEPOC|Ensembl=ENSLOCG00000015396.1|UniProtKB=W5NE85 W5NE85 PTHR24351:SF199 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004875.1|UniProtKB=W5MBV3 W5MBV3 PTHR11071:SF577 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000944.1|UniProtKB=W5LY46 W5LY46 PTHR47008:SF1 PROTEIN CORDON-BLEU PROTEIN CORDON-BLEU cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;perinuclear region of cytoplasm#GO:0048471;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;ruffle#GO:0001726;distal axon#GO:0150034;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cortical cytoskeleton#GO:0030863;neuronal cell body#GO:0043025;dendrite#GO:0030425;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;cell cortex#GO:0005938;dendritic tree#GO:0097447;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonal growth cone#GO:0044295;cell body#GO:0044297;neuron projection#GO:0043005;cytoskeleton#GO:0005856;growth cone#GO:0030426;site of polarized growth#GO:0030427;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013998.1|UniProtKB=W5N9E8 W5N9E8 PTHR43599:SF11 MULTIFUNCTIONAL PROTEIN ADE2 BIFUNCTIONAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE_PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012581.1|UniProtKB=W5N4C8 W5N4C8 PTHR23356:SF16 DPY30-RELATED DPY30 DOMAIN CONTAINING 2 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000001833.1|UniProtKB=W5M184 W5M184 PTHR11945:SF25 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2C cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2C#P07222;Oxidative stress response#P00046>MEF-2#P01128 LEPOC|Ensembl=ENSLOCG00000008058.1|UniProtKB=W5MN26 W5MN26 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN UL24M macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015633.1|UniProtKB=W5NF39 W5NF39 PTHR12786:SF1 SPLICING FACTOR SF3A-RELATED SPLICING REGULATOR SDE2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005192.1|UniProtKB=W5MCZ1 W5MCZ1 PTHR45689:SF11 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;regulation of membrane depolarization#GO:0003254;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007129.1|UniProtKB=W5MJS7 W5MJS7 PTHR24033:SF151 EGF-LIKE DOMAIN-CONTAINING PROTEIN NOTCH 2 LEPOC|Ensembl=ENSLOCG00000003046.1|UniProtKB=W5M5C9 W5M5C9 PTHR10736:SF55 BESTROPHIN BESTROPHIN-4 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012228.1|UniProtKB=W5N335 W5N335 PTHR43880:SF21 ALCOHOL DEHYDROGENASE S-(HYDROXYMETHYL)GLUTATHIONE DEHYDROGENASE cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;cellular process#GO:0009987;response to stimulus#GO:0050896;detoxification#GO:0098754;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010152.1|UniProtKB=W5MVM1 W5MVM1 CATSPER3 PTHR47131:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;establishment of localization#GO:0051234;spermatogenesis#GO:0007283;monoatomic cation transport#GO:0006812;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;metal ion transport#GO:0030001;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;sodium ion transport#GO:0006814;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 membrane protein complex#GO:0098796;acrosomal vesicle#GO:0001669;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;secretory granule#GO:0030141;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013132.1|UniProtKB=W5N6D1 W5N6D1 PTHR11792:SF20 ARRESTIN BETA-ARRESTIN-2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;receptor internalization#GO:0031623;positive regulation of signal transduction#GO:0009967;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;receptor-mediated endocytosis#GO:0006898;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;localization#GO:0051179;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;positive regulation of ERK1 and ERK2 cascade#GO:0070374;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR2#P05923;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 LEPOC|Ensembl=ENSLOCG00000004845.1|UniProtKB=W5MBR5 W5MBR5 PTHR14690:SF11 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 IQ AND AAA DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000011544.1|UniProtKB=W5N0M3 W5N0M3 PTHR23192:SF29 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016968.1|UniProtKB=W5NK16 W5NK16 PTHR15532:SF3 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000007838.1|UniProtKB=W5MMA3 W5MMA3 PTHR14297:SF8 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER ENDOPLASMIC RETICULUM MEMBRANE ADAPTER PROTEIN XK LEPOC|Ensembl=ENSLOCG00000006447.1|UniProtKB=W5MHD0 W5MHD0 PTHR10779:SF17 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 microtubule organizing center#GO:0005815;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cytoplasmic dynein complex#GO:0005868 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000013144.1|UniProtKB=W5N6E2 W5N6E2 PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013367.1|UniProtKB=W5N763 W5N763 PAQR9 PTHR20855:SF143 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR EPSILON signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000349.1|UniProtKB=W5LW74 W5LW74 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;late endosome to vacuole transport#GO:0045324;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015268.1|UniProtKB=W5NDS7 W5NDS7 PTHR31443:SF0 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 LEPOC|Ensembl=ENSLOCG00000008820.1|UniProtKB=W5MQS4 W5MQS4 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016041.1|UniProtKB=W5NGK3 W5NGK3 PTHR11958:SF20 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER A inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015075.1|UniProtKB=W5ND43 W5ND43 PTHR22576:SF41 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE CASPASE 14, APOPTOSIS-RELATED CYSTEINE PEPTIDASE cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007902.1|UniProtKB=W5MMI7 W5MMI7 PTHR12704:SF4 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3-LIKE lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013520.1|UniProtKB=W5N7R2 W5N7R2 PTHR12696:SF2 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013003.1|UniProtKB=W5N5W0 W5N5W0 PTHR16399:SF18 GASDERMIN GASDERMIN-A transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010589.1|UniProtKB=W5MX67 W5MX67 PTHR45639:SF6 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000016203.1|UniProtKB=W5NH63 W5NH63 PTHR16188:SF6 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000006367.1|UniProtKB=W5MH27 W5MH27 PTHR47224:SF1 TRANSMEMBRANE PROTEIN 25 TRANSMEMBRANE PROTEIN 25 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of membrane potential#GO:0042391;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of system process#GO:0044057 LEPOC|Ensembl=ENSLOCG00000006401.1|UniProtKB=W5MH70 W5MH70 PTHR24372:SF67 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of adenylate cyclase activity#GO:0045762;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of Wnt signaling pathway#GO:0030177;regulation of catalytic activity#GO:0050790;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;positive regulation of catalytic activity#GO:0043085;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002733.1|UniProtKB=W5M4B6 W5M4B6 PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000004159.1|UniProtKB=W5M9C7 W5M9C7 PTHR24023:SF958 COLLAGEN ALPHA COLLAGEN ALPHA-1(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000014341.1|UniProtKB=W5NAK0 W5NAK0 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000017853.1|UniProtKB=W5NMU7 W5NMU7 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001415.1|UniProtKB=W5LZQ2 W5LZQ2 PTHR10462:SF51 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017495.1|UniProtKB=W5NLU1 W5NLU1 PTHR14491:SF8 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHD LEPOC|Ensembl=ENSLOCG00000009419.1|UniProtKB=W5MSY4 W5MSY4 PTHR46359:SF1 GEO07743P1 RING FINGER PROTEIN 11 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000016734.1|UniProtKB=W5NJ70 W5NJ70 PTHR10257:SF89 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT DELTA ISOFORM phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000005300.1|UniProtKB=W5MDC7 W5MDC7 PTHR12461:SF104 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;glycosyl compound metabolic process#GO:1901657 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002623.1|UniProtKB=W5M3Y0 W5M3Y0 PTHR12349:SF4 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000012655.1|UniProtKB=W5N4L8 W5N4L8 PTHR46439:SF1 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN CYSTEINE-RICH MOTOR NEURON 1 PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001356.1|UniProtKB=W5LZJ0 W5LZJ0 PTHR23151:SF90 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003812.1|UniProtKB=W5M842 W5M842 PTHR10225:SF2 HYALURONAN RECEPTOR LYMPHATIC VESSEL ENDOTHELIAL HYALURONIC ACID RECEPTOR 1 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009042.1|UniProtKB=W5MRL7 W5MRL7 PTHR11353:SF19 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000010257.1|UniProtKB=W5MW10 W5MW10 PTHR15036:SF40 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 4 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003874.1|UniProtKB=W5M8B1 W5M8B1 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005910.1|UniProtKB=W5MFH6 W5MFH6 PTHR10071:SF289 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;striated muscle tissue development#GO:0014706;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;muscle tissue development#GO:0060537;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015249.1|UniProtKB=W5NDR2 W5NDR2 PTHR20856:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000009990.1|UniProtKB=W5MV08 W5MV08 TLR8 PTHR47410:SF1 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;activation of immune response#GO:0002253;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;canonical NF-kappaB signal transduction#GO:0007249;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;positive regulation of macromolecule metabolic process#GO:0010604;defense response to symbiont#GO:0140546;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;signal transduction#GO:0007165;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cytokine production#GO:0001817;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000002522.1|UniProtKB=W5M3K8 W5M3K8 PTHR12783:SF5 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000013289.1|UniProtKB=W5N6W3 W5N6W3 PTHR11630:SF93 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000018142.1|UniProtKB=W5NNN4 W5NNN4 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000008980.1|UniProtKB=W5MRD3 W5MRD3 PTHR24099:SF18 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM36 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 fertilization#GO:0009566;single fertilization#GO:0007338;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;acrosome reaction#GO:0007340 cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008716.1|UniProtKB=W5MQH9 W5MQH9 PTHR14149:SF10 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP3 nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;actin filament binding#GO:0051015;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;actin binding#GO:0003779;enzyme regulator activity#GO:0030234 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring assembly#GO:0000915;mitotic cytokinetic process#GO:1902410;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament organization#GO:0007015;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000011278.1|UniProtKB=W5MZQ6 W5MZQ6 PTHR47219:SF13 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RUN AND TBC1 DOMAIN-CONTAINING PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000006252.1|UniProtKB=W5MGP8 W5MGP8 PTHR24027:SF79 CADHERIN-23 CADHERIN-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;system development#GO:0048731;synapse assembly#GO:0007416;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;cell junction assembly#GO:0034329;cell migration#GO:0016477;adherens junction organization#GO:0034332 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;asymmetric synapse#GO:0032279;apical part of cell#GO:0045177;extrinsic component of membrane#GO:0019898;cell leading edge#GO:0031252;lamellipodium#GO:0030027;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;membrane protein complex#GO:0098796;presynapse#GO:0098793;postsynaptic specialization#GO:0099572;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intercalated disc#GO:0014704;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000000901.1|UniProtKB=W5LXZ4 W5LXZ4 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014029.1|UniProtKB=W5N9I4 W5N9I4 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4 LIKE 2 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016208.1|UniProtKB=W5NH69 W5NH69 BCLAF1 PTHR15268:SF4 THRAP3/BCLAF1 BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005336.1|UniProtKB=W5MDI2 W5MDI2 PTHR24393:SF5 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM16 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014654.1|UniProtKB=W5NBM9 W5NBM9 PTHR10015:SF185 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 2 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003710.1|UniProtKB=W5M7Q4 W5M7Q4 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 LEPOC|Ensembl=ENSLOCG00000010650.1|UniProtKB=W5MXD7 W5MXD7 PTHR10844:SF16 CAVEOLIN CAVEOLIN-3 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;calcium ion homeostasis#GO:0055074;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;regulation of membrane potential#GO:0042391;developmental process#GO:0032502;endomembrane system organization#GO:0010256;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;membrane assembly#GO:0071709;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873 plasma membrane raft#GO:0044853;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;caveola#GO:0005901;plasma membrane region#GO:0098590;cell-substrate junction#GO:0030055;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;sarcolemma#GO:0042383;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015719.1|UniProtKB=W5NFE0 W5NFE0 PTHR31553:SF2 NF-KAPPA-B ESSENTIAL MODULATOR OPTINEURIN protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 regulation of cell communication#GO:0010646;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;regulation of signaling#GO:0023051;endomembrane system organization#GO:0010256;protein localization to Golgi apparatus#GO:0034067;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Huntington disease#P00029>FIP-2#P00772 LEPOC|Ensembl=ENSLOCG00000010256.1|UniProtKB=W5MVZ3 W5MVZ3 PTHR24056:SF159 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 15 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002944.1|UniProtKB=W5M514 W5M514 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001210.1|UniProtKB=W5LZ07 W5LZ07 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014647.1|UniProtKB=W5NBL9 W5NBL9 PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009211.1|UniProtKB=W5MS84 W5MS84 PTHR24278:SF0 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN C extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 Blood coagulation#P00011>PC#P00426;Blood coagulation#P00011>APC#P00423 LEPOC|Ensembl=ENSLOCG00000002159.1|UniProtKB=W5M2C8 W5M2C8 PTHR18916:SF10 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010030.1|UniProtKB=W5MV54 W5MV54 PTHR24023:SF1100 COLLAGEN ALPHA FIBRILLAR COLLAGEN NC1 DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000002869.1|UniProtKB=W5M4S0 W5M4S0 PTHR45949:SF1 SORTING NEXIN-4 SORTING NEXIN-30 endosomal transport#GO:0016197;microautophagy#GO:0016237;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;autophagy of mitochondrion#GO:0000422;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 cytoplasm#GO:0005737;endosome#GO:0005768;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009706.1|UniProtKB=W5MTZ3 W5MTZ3 PTHR12210:SF43 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010385.1|UniProtKB=W5MWH4 W5MWH4 PTHR43816:SF2 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017294.1|UniProtKB=W5NL90 W5NL90 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011783.1|UniProtKB=W5N1I5 W5N1I5 PTHR21040:SF6 BCDNA.GH04120 HEXOSAMINIDASE D hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000017907.1|UniProtKB=W5NN01 W5NN01 PTHR19268:SF7 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 85-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015091.1|UniProtKB=W5ND66 W5ND66 PTHR13318:SF254 PARTNER OF PAIRED, ISOFORM B-RELATED PROTEIN AMN1 HOMOLOG macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000013857.1|UniProtKB=W5N8Y3 W5N8Y3 PTHR11977:SF127 VILLIN MACROPHAGE-CAPPING PROTEIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;cellular component biogenesis#GO:0044085;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;central nervous system development#GO:0007417;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;cell projection assembly#GO:0030031;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000015109.1|UniProtKB=W5ND87 W5ND87 PTHR46849:SF1 RCC1 DOMAIN-CONTAINING PROTEIN 1 RCC1 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009937.1|UniProtKB=W5MUU7 W5MUU7 PTHR45783:SF7 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 1 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000006617.1|UniProtKB=W5MI13 W5MI13 PTHR45750:SF2 GH11602P HISTONE ACETYLTRANSFERASE KAT2B histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 p53 pathway#P00059>PCAF#P04629;Gonadotropin-releasing hormone receptor pathway#P06664>Pcaf#P06715 LEPOC|Ensembl=ENSLOCG00000014881.1|UniProtKB=W5NCG6 W5NCG6 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009719.1|UniProtKB=W5MU50 W5MU50 PTHR24023:SF714 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;kidney development#GO:0001822;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000006830.1|UniProtKB=W5MIT0 W5MIT0 PTHR24025:SF0 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000002399.1|UniProtKB=W5M348 W5M348 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016456.1|UniProtKB=W5NI65 W5NI65 PTHR47027:SF25 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012605.1|UniProtKB=W5N4F8 W5N4F8 PTHR12738:SF0 NEUROENDOCRINE PROTEIN 7B2 NEUROENDOCRINE PROTEIN 7B2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of hormone secretion#GO:0046883;biological regulation#GO:0065007;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of hormone levels#GO:0010817 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011445.1|UniProtKB=W5N0A5 W5N0A5 SFRP4 PTHR11309:SF7 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461 LEPOC|Ensembl=ENSLOCG00000001042.1|UniProtKB=W5LYG4 W5LYG4 PTHR46262:SF1 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000011660.1|UniProtKB=W5N118 W5N118 PTHR16231:SF0 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000005800.1|UniProtKB=W5MF46 W5MF46 PTHR24115:SF744 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006258.1|UniProtKB=W5MGQ2 W5MGQ2 PTHR31915:SF5 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000003333.1|UniProtKB=W5M6D1 W5M6D1 PTHR37397:SF1 SI:CH211-183D21.1 LTD DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014106.1|UniProtKB=W5N9S0 W5N9S0 PTHR21142:SF2 SARCOGLYCANS BETA-SARCOGLYCAN membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000016591.1|UniProtKB=W5NIN8 W5NIN8 PTHR11042:SF75 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE 2 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of nuclear division#GO:0051783;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;regulation of cellular component organization#GO:0051128;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017307.1|UniProtKB=W5NLA3 W5NLA3 PTHR11437:SF10 RIBONUCLEASE ANGIOGENIN-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001722.1|UniProtKB=W5M0T6 W5M0T6 ADAP1 PTHR46021:SF5 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011602.1|UniProtKB=W5N0U7 W5N0U7 PTHR24106:SF283 NACHT, LRR AND CARD DOMAINS-CONTAINING NACHT DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016198.1|UniProtKB=W5NH59 W5NH59 PTHR47966:SF37 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN E-A-LIKE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014548.1|UniProtKB=W5NBA0 W5NBA0 PTHR12722:SF0 XAP-5 PROTEIN-RELATED PROTEIN FAM50A cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011627.1|UniProtKB=W5N0X9 W5N0X9 PTHR12962:SF4 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED COLD SHOCK DOMAIN-CONTAINING PROTEIN C2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004282.1|UniProtKB=W5M9Q7 W5M9Q7 PTHR31690:SF4 FUCOSE MUTAROTASE FUCOSE MUTAROTASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;carbohydrate binding#GO:0030246;isomerase activity#GO:0016853;small molecule binding#GO:0036094;monosaccharide binding#GO:0048029;binding#GO:0005488;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;glycosylation#GO:0070085;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000002643.1|UniProtKB=W5M412 W5M412 PTHR18902:SF26 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GOLGIN SUBFAMILY A MEMBER 3 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007300.1|UniProtKB=W5MKD8 W5MKD8 PTHR15735:SF17 FCH AND DOUBLE SH3 DOMAINS PROTEIN CDC42-INTERACTING PROTEIN 4 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005942.1|UniProtKB=W5MFL9 W5MFL9 PTHR11568:SF2 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007287.1|UniProtKB=W5MKB0 W5MKB0 PTHR10424:SF81 VIRAL ENVELOPE PROTEIN ERVV2 PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012672.1|UniProtKB=W5N4N9 W5N4N9 PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 cellular localization#GO:0051641;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule localization#GO:0033036;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular macromolecule localization#GO:0070727;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 LEPOC|Ensembl=ENSLOCG00000015778.1|UniProtKB=W5NFL6 W5NFL6 PTHR23147:SF220 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 7B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004060.1|UniProtKB=W5M8Z5 W5M8Z5 CNDP1 PTHR43270:SF16 BETA-ALA-HIS DIPEPTIDASE BETA-ALA-HIS DIPEPTIDASE-LIKE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012198.1|UniProtKB=W5N300 W5N300 PTHR11960:SF74 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015732.1|UniProtKB=W5NFF8 W5NFF8 PTHR24261:SF13 PLASMINOGEN-RELATED PLASMINOGEN binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;signaling receptor binding#GO:0005102 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 Blood coagulation#P00011>Plasmin#P00415;Blood coagulation#P00011>Plasminogen#P00408;Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 LEPOC|Ensembl=ENSLOCG00000001506.1|UniProtKB=W5M049 W5M049 PTHR11884:SF1 SELECTIN LIGAND RELATED GOLGI APPARATUS PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012541.1|UniProtKB=W5N492 W5N492 PTHR46071:SF3 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002007.1|UniProtKB=W5M1R9 W5M1R9 PTHR45729:SF9 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN BETA neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;regulation of secretion by cell#GO:1903530;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cell communication#GO:0007154;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;signal release from synapse#GO:0099643;regulation of transport#GO:0051049;exocytosis#GO:0006887;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment of localization in cell#GO:0051649;cell-cell signaling#GO:0007267;signaling#GO:0023052;export from cell#GO:0140352;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002654.1|UniProtKB=W5M417 W5M417 PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;rRNA metabolic process#GO:0016072;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015388.1|UniProtKB=W5NE76 W5NE76 SPX PTHR28590:SF1 SPEXIN SPEXIN LEPOC|Ensembl=ENSLOCG00000009667.1|UniProtKB=W5MTV0 W5MTV0 PTHR23055:SF82 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 1 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;channel regulator activity#GO:0016247;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008210.1|UniProtKB=W5MNL0 W5MNL0 PTHR13068:SF194 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;aromatic compound biosynthetic process#GO:0019438 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016401.1|UniProtKB=W5NHZ4 W5NHZ4 PTHR24107:SF27 YNEIN REGULATORY COMPLEX SUBUNIT 5 DYNEIN REGULATORY COMPLEX SUBUNIT 5 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000008804.1|UniProtKB=W5MQQ7 W5MQQ7 SYDE1 PTHR46150:SF2 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 synapse#GO:0045202;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001912.1|UniProtKB=W5M1F2 W5M1F2 PTHR24329:SF337 HOMEOBOX PROTEIN ARISTALESS ARISTALESS RELATED HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014854.1|UniProtKB=W5NCD3 W5NCD3 PTHR14166:SF16 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 4 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of locomotion#GO:0040013;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 CCKR signaling map#P06959>ARHGAP4#P07135;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000012322.1|UniProtKB=W5N3F7 W5N3F7 PTHR10306:SF9 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE PROTEIN 1 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003683.1|UniProtKB=W5M7L3 W5M7L3 PTHR12630:SF6 N-LINKED OLIGOSACCHARIDE PROCESSING N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010883.1|UniProtKB=W5MY84 W5MY84 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005959.1|UniProtKB=W5MFQ0 W5MFQ0 DNAH10 PTHR22878:SF63 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED DYNEIN AXONEMAL HEAVY CHAIN 10 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000013990.1|UniProtKB=W5N9D9 W5N9D9 PTHR12002:SF74 CLAUDIN CLAUDIN-15 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000011412.1|UniProtKB=W5N084 W5N084 PTHR46767:SF1 LIM DOMAIN ONLY PROTEIN 7 LIM DOMAIN ONLY PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000002334.1|UniProtKB=W5M2Y9 W5M2Y9 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009577.1|UniProtKB=W5MTJ8 W5MTJ8 PTHR23257:SF969 SERINE-THREONINE PROTEIN KINASE INTEGRIN-LINKED PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014689.1|UniProtKB=W5NBS0 W5NBS0 PTHR15304:SF4 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR-LIKE LEPOC|Ensembl=ENSLOCG00000012278.1|UniProtKB=W5N3A1 W5N3A1 PTHR46628:SF1 PIRNA BIOGENESIS PROTEIN EXD1 PIRNA BIOGENESIS PROTEIN EXD1 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;piRNA processing#GO:0034587;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000016112.1|UniProtKB=W5NGU4 W5NGU4 PTHR43563:SF14 AMINE OXIDASE AMINE OXIDASE oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013675.1|UniProtKB=W5N898 W5N898 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003014.1|UniProtKB=W5M587 W5M587 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000006181.1|UniProtKB=W5MGF9 W5MGF9 PTHR24366:SF169 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS PODOCAN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007962.1|UniProtKB=W5MMQ8 W5MMQ8 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012895.1|UniProtKB=W5N5G9 W5N5G9 PTHR22957:SF204 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000007982.1|UniProtKB=W5MMU4 W5MMU4 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005806.1|UniProtKB=W5MF49 W5MF49 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015897.1|UniProtKB=W5NG18 W5NG18 PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;dicarboxylic acid metabolic process#GO:0043648;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008830.1|UniProtKB=W5MQT5 W5MQT5 PTHR10332:SF17 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012426.1|UniProtKB=W5N3U7 W5N3U7 PTHR11227:SF23 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 1 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004290.1|UniProtKB=W5M9S8 W5M9S8 PTHR12587:SF18 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-2 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330;neuromuscular junction development#GO:0007528 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011727.1|UniProtKB=W5N1A6 W5N1A6 PTHR10417:SF3 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018096.1|UniProtKB=W5NNI8 W5NNI8 PTHR21255:SF55 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 4 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011659.1|UniProtKB=W5N122 W5N122 PTHR12697:SF20 PBS LYASE HEAT-LIKE PROTEIN HEAT REPEAT-CONTAINING PROTEIN 4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000006544.1|UniProtKB=W5MHQ5 W5MHQ5 PTHR46097:SF1 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 head development#GO:0060322;regulation of cell communication#GO:0010646;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;brain development#GO:0007420;vesicle-mediated transport#GO:0016192;regulation of G protein-coupled receptor signaling pathway#GO:0008277;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;system development#GO:0048731;synaptic vesicle recycling#GO:0036465;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;central nervous system development#GO:0007417;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;postsynapse#GO:0098794;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005616.1|UniProtKB=W5MEG7 W5MEG7 PTHR24366:SF37 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT, IG-LIKE AND TRANSMEMBRANE DOMAINS 1 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000016597.1|UniProtKB=W5NIN9 W5NIN9 PTHR31017:SF2 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED DENN DOMAIN-CONTAINING PROTEIN 11 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004332.1|UniProtKB=W5M9X0 W5M9X0 PHLPP2 PTHR45752:SF10 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005027.1|UniProtKB=W5MCE5 W5MCE5 PTHR21243:SF15 PROTEIN SCAI PROTEIN SCAI transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008077.1|UniProtKB=W5MN54 W5MN54 PTHR12276:SF48 EPSIN/ENT-RELATED EPSIN-1 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000006693.1|UniProtKB=W5MI72 W5MI72 PTHR10151:SF65 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7-LIKE PRECURSOR metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016416.1|UniProtKB=W5NI16 W5NI16 PTHR28654:SF1 AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001899.1|UniProtKB=W5M1E8 W5M1E8 PTHR15706:SF6 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 1-RELATED enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005957.1|UniProtKB=W5MFN5 W5MFN5 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000017909.1|UniProtKB=W5NN03 W5NN03 PTHR11537:SF24 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;main axon#GO:0044304;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000009657.1|UniProtKB=W5MTU2 W5MTU2 PTHR24240:SF138 OPSIN NOVOPSIN-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003662.1|UniProtKB=W5M7I8 W5M7I8 PTHR24027:SF433 CADHERIN-23 CADHERIN 27-RELATED cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001768.1|UniProtKB=W5M0Z9 W5M0Z9 PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000013641.1|UniProtKB=W5N869 W5N869 PTHR46462:SF1 UPSET, ISOFORM A HISTONE-LYSINE N-METHYLTRANSFERASE SETD5 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;Rpd3L-Expanded complex#GO:0070210;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004184.1|UniProtKB=W5M9F7 W5M9F7 PIF1 PTHR23274:SF11 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE PIF1 DNA metabolism protein#PC00009;DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000006361.1|UniProtKB=W5MH26 W5MH26 PTHR10814:SF33 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 7 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000000547.1|UniProtKB=W5LWU6 W5LWU6 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007031.1|UniProtKB=W5MJF6 W5MJF6 PTHR19353:SF12 FATTY ACID DESATURASE 2 ACYL-COA 6-DESATURASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000937.1|UniProtKB=W5LY38 W5LY38 PTHR10489:SF594 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 4 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 head development#GO:0060322;signal transduction#GO:0007165;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;animal organ development#GO:0048513;developmental process#GO:0032502;positive regulation of cytosolic calcium ion concentration#GO:0007204;brain development#GO:0007420;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biological quality#GO:0065008;central nervous system development#GO:0007417;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Axon guidance mediated by Slit/Robo#P00008>Cxcr4#P00351;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000013812.1|UniProtKB=W5N8S7 W5N8S7 PTHR13532:SF3 FAMILY NOT NAMED INTEGRATOR COMPLEX SUBUNIT 14 LEPOC|Ensembl=ENSLOCG00000013041.1|UniProtKB=W5N613 W5N613 PTHR11339:SF374 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED ZONADHESIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013417.1|UniProtKB=W5N7D5 W5N7D5 PTHR22812:SF159 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014187.1|UniProtKB=W5NA16 W5NA16 PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macroautophagy#GO:0016236;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;regulation of protein localization#GO:0032880;organelle fusion#GO:0048284;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;Golgi organization#GO:0007030;vacuolar transport#GO:0007034;regulation of protein localization to membrane#GO:1905475;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;Golgi to vacuole transport#GO:0006896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;membrane#GO:0016020;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 LEPOC|Ensembl=ENSLOCG00000015745.1|UniProtKB=W5NFH3 W5NFH3 PTHR10574:SF419 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-3-RELATED neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000011164.1|UniProtKB=W5MZB1 W5MZB1 PTHR13793:SF150 PHD FINGER PROTEINS PHD FINGER PROTEIN 14 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016063.1|UniProtKB=W5NGN7 W5NGN7 PTHR23382:SF3 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;dicarboxylic acid metabolic process#GO:0043648;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 TCA cycle#P00051>Malate Dehydrogenase#P01270 LEPOC|Ensembl=ENSLOCG00000009887.1|UniProtKB=W5MUN2 W5MUN2 PTHR16254:SF14 POTASSIUM/PROTON ANTIPORTER-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000006790.1|UniProtKB=W5MIJ9 W5MIJ9 PTHR18945:SF751 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL NICOTINIC ACETYLOCHOLINE RECEPTOR ALPHA-7 SUBUNIT-LIKE PRECURSOR transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014398.1|UniProtKB=W5NAR6 W5NAR6 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002290.1|UniProtKB=W5M2R6 W5M2R6 PTHR11158:SF24 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING 1B phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000012221.1|UniProtKB=W5N330 W5N330 PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011824.1|UniProtKB=W5N1M9 W5N1M9 PTHR45659:SF10 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010433.1|UniProtKB=W5MWN0 W5MWN0 PTHR15286:SF16 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008277.1|UniProtKB=W5MNU4 W5MNU4 HINT1 PTHR23089:SF33 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000016861.1|UniProtKB=W5NJP3 W5NJP3 PTHR19143:SF199 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-2 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-2#P00246 LEPOC|Ensembl=ENSLOCG00000001997.1|UniProtKB=W5M1R3 W5M1R3 PTHR11878:SF26 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 4 ISOFORM B calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;axon#GO:0030424;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000296.1|UniProtKB=W5LW15 W5LW15 PTHR25466:SF11 T-LYMPHOCYTE ACTIVATION ANTIGEN GALECTIN 17-RELATED response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014900.1|UniProtKB=W5NCI8 W5NCI8 PTHR21258:SF14 DOCKING PROTEIN RELATED DOCKING PROTEIN 2 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 LEPOC|Ensembl=ENSLOCG00000001051.1|UniProtKB=W5LYH5 W5LYH5 PTHR24103:SF695 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-18P12.4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001049.1|UniProtKB=W5LYH0 W5LYH0 PTHR24373:SF352 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TSUKUSHI external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004296.1|UniProtKB=W5M9S0 W5M9S0 PTHR43466:SF1 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 LEPOC|Ensembl=ENSLOCG00000012577.1|UniProtKB=W5N4C4 W5N4C4 PTHR16830:SF12 SH2 CONTAINING ADAPTOR PRAM-1 RELATED PDZ DOMAIN-CONTAINING PROTEIN protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002512.1|UniProtKB=W5M3J2 W5M3J2 PTHR10110:SF86 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011653.1|UniProtKB=W5N110 W5N110 PTHR10533:SF5 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PRO-NEUROPEPTIDE Y neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;behavior#GO:0007610;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;feeding behavior#GO:0007631;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008945.1|UniProtKB=W5MR88 W5MR88 PTHR24173:SF14 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG C macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001777.1|UniProtKB=W5M103 W5M103 PTHR45674:SF4 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 1 DNA ligase#PC00012 LEPOC|Ensembl=ENSLOCG00000015263.1|UniProtKB=W5NDS4 W5NDS4 PTHR46780:SF5 PROTEIN EVA-1 SUEL-TYPE LECTIN DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015977.1|UniProtKB=W5NGB2 W5NGB2 PTHR10239:SF30 ISTHMIN-2 ISTHMIN-1 regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of vasculature development#GO:1901342;regulation of anatomical structure morphogenesis#GO:0022603;biological regulation#GO:0065007;negative regulation of angiogenesis#GO:0016525;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026 LEPOC|Ensembl=ENSLOCG00000014121.1|UniProtKB=W5N9U0 W5N9U0 PTHR11679:SF71 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001641.1|UniProtKB=W5M0I9 W5M0I9 PTHR15672:SF12 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000056.1|UniProtKB=W5LVA9 W5LVA9 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014075.1|UniProtKB=W5N9N9 W5N9N9 PTHR23003:SF63 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE AND ARGININE-RICH-SPLICING FACTOR 5A nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001728.1|UniProtKB=W5M0V7 W5M0V7 CEP89 PTHR36170:SF1 CENTROSOMAL PROTEIN OF 89 KDA CENTROSOMAL PROTEIN OF 89 KDA organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ciliary transition fiber#GO:0097539;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000000255.1|UniProtKB=W5LVX3 W5LVX3 PTHR33769:SF3 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 MESENTERIC ESTROGEN-DEPENDENT ADIPOGENESIS PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013286.1|UniProtKB=W5N6V9 W5N6V9 PTHR23353:SF34 RAB-GAP/TBC-RELATED TBC1 DOMAIN FAMILY MEMBER 24 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 LEPOC|Ensembl=ENSLOCG00000005582.1|UniProtKB=W5MEC8 W5MEC8 PTHR45857:SF5 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cell shape#GO:0008360;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001098.1|UniProtKB=W5LYQ0 W5LYQ0 PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000006595.1|UniProtKB=W5MHY0 W5MHY0 PTHR12203:SF35 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 LEPOC|Ensembl=ENSLOCG00000001310.1|UniProtKB=W5LZD4 W5LZD4 PTHR23266:SF322 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-8 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014558.1|UniProtKB=W5NBA8 W5NBA8 PTHR45870:SF2 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007978.1|UniProtKB=W5MMU5 W5MMU5 PTHR24416:SF306 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005748.1|UniProtKB=W5MEY7 W5MEY7 PTHR13140:SF381 MYOSIN UNCONVENTIONAL MYOSIN-IG microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 actin filament-based movement#GO:0030048;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000008889.1|UniProtKB=W5MR12 W5MR12 PTHR13718:SF4 RIBOSOMAL S SUBUNIT 40S RIBOSOMAL PROTEIN S2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005709.1|UniProtKB=W5MET7 W5MET7 PTHR10133:SF62 DNA POLYMERASE I DNA POLYMERASE THETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001400.1|UniProtKB=W5LZN8 W5LZN8 PTHR22776:SF10 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 8 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003250.1|UniProtKB=W5M636 W5M636 PTHR11562:SF37 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A8 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 cellular localization#GO:0051641;macromolecule localization#GO:0033036;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;peptide secretion#GO:0002790;inorganic ion transmembrane transport#GO:0098660;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;hormone secretion#GO:0046879;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;peptide hormone secretion#GO:0030072;signal release#GO:0023061;monoatomic cation transport#GO:0006812;insulin secretion#GO:0030073;transition metal ion transport#GO:0000041;hormone transport#GO:0009914;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;response to organic substance#GO:0010033;metal ion transport#GO:0030001;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;cell communication#GO:0007154;peptide transport#GO:0015833;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;response to stimulus#GO:0050896;establishment of protein localization to extracellular region#GO:0035592;response to glucose#GO:0009749;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;monoatomic ion transmembrane transport#GO:0034220;protein transport#GO:0015031;biological regulation#GO:0065007;monoatomic ion transport#GO:0006811;protein localization to extracellular region#GO:0071692;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006248.1|UniProtKB=W5MGP3 W5MGP3 TUT4 PTHR12271:SF49 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 4 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000012922.1|UniProtKB=W5N5K7 W5N5K7 PTHR15551:SF3 LIM DOMAIN ONLY 7 LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014733.1|UniProtKB=W5NBZ7 W5NBZ7 HCFC1 PTHR46003:SF3 HOST CELL FACTOR HOST CELL FACTOR 1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005356.1|UniProtKB=W5MDJ0 W5MDJ0 PTHR24271:SF81 KALLIKREIN-RELATED GRANZYME B serine protease#PC00203;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Granzyme B#P00265 LEPOC|Ensembl=ENSLOCG00000016393.1|UniProtKB=W5NHY5 W5NHY5 PTHR45712:SF18 AGAP008170-PA PODOCAN-LIKE PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000002782.1|UniProtKB=W5M4H8 W5M4H8 PTHR10082:SF3 INTEGRIN BETA SUBUNIT INTEGRIN BETA-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000013468.1|UniProtKB=W5N7K4 W5N7K4 UBE2O PTHR46116:SF15 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003050.1|UniProtKB=W5M5E2 W5M5E2 PTHR23308:SF28 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000003990.1|UniProtKB=W5M8Q3 W5M8Q3 PTHR16024:SF13 XK-RELATED PROTEIN XK-RELATED PROTEIN 9 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017302.1|UniProtKB=W5NL98 W5NL98 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001432.1|UniProtKB=W5LZT0 W5LZT0 PTHR23288:SF8 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008142.1|UniProtKB=W5MNC5 W5MNC5 PTHR20859:SF22 INTERFERON/INTERLEUKIN RECEPTOR TISSUE FACTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Blood coagulation#P00011>Tissue Factor#P00450;Angiogenesis#P00005>TF#P00191 LEPOC|Ensembl=ENSLOCG00000010851.1|UniProtKB=W5MY42 W5MY42 PTHR11711:SF146 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5B carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015631.1|UniProtKB=W5NF36 W5NF36 PTHR14146:SF0 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017421.1|UniProtKB=W5NLL7 W5NLL7 PTHR14527:SF2 PROTEIN MIS12 HOMOLOG PROTEIN MIS12 HOMOLOG cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;protein-DNA complex organization#GO:0071824;kinetochore organization#GO:0051383;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;kinetochore assembly#GO:0051382;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;outer kinetochore#GO:0000940;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004776.1|UniProtKB=W5MBM6 W5MBM6 PTHR15729:SF13 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 32 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;Golgi apparatus#GO:0005794;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 GTPase-activating protein#PC00257 Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06882;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#P06765;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06669 LEPOC|Ensembl=ENSLOCG00000016991.1|UniProtKB=W5NK44 W5NK44 PTHR11360:SF119 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 10 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002543.1|UniProtKB=W5M3M4 W5M3M4 CDC20B PTHR19918:SF4 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG B protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012595.1|UniProtKB=W5N4E9 W5N4E9 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014822.1|UniProtKB=W5NC90 W5NC90 PTHR10032:SF273 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS OVO LIKE ZINC FINGER 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;epidermal cell differentiation#GO:0009913;regulation of DNA-templated transcription#GO:0006355;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;epidermis development#GO:0008544;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010403.1|UniProtKB=W5MWL9 W5MWL9 EML5 PTHR13720:SF16 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 5 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016301.1|UniProtKB=W5NHL4 W5NHL4 PTHR11361:SF35 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH2 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000817.1|UniProtKB=W5LXQ1 W5LXQ1 PTHR10071:SF154 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 LEPOC|Ensembl=ENSLOCG00000010268.1|UniProtKB=W5MW31 W5MW31 PTHR46089:SF3 ALSIN HOMOLOG ALSIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;transport#GO:0006810;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987 somatodendritic compartment#GO:0036477;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000002846.1|UniProtKB=W5M4N9 W5M4N9 PTHR23050:SF23 CALCIUM BINDING PROTEIN AT22559P-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000004180.1|UniProtKB=W5M9F3 W5M9F3 PTHR22940:SF4 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;intracellular signal transduction#GO:0035556;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 LEPOC|Ensembl=ENSLOCG00000011091.1|UniProtKB=W5MZ15 W5MZ15 PTHR46282:SF1 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72-LIKE LEPOC|Ensembl=ENSLOCG00000013439.1|UniProtKB=W5N7G8 W5N7G8 PTHR11481:SF5 IMMUNOGLOBULIN FC RECEPTOR PLATELET ENDOTHELIAL CELL ADHESION MOLECULE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003577.1|UniProtKB=W5M787 W5M787 PTHR12801:SF158 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000008223.1|UniProtKB=W5MNN0 W5MNN0 PTHR24044:SF467 NOTCH LIGAND FAMILY MEMBER DELTA AND NOTCH-LIKE EPIDERMAL GROWTH FACTOR-RELATED RECEPTOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007320.1|UniProtKB=W5MKF8 W5MKF8 PTHR10134:SF20 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009631.1|UniProtKB=W5MTR0 W5MTR0 PTHR46436:SF1 CENTROSOMAL PROTEIN OF 76 KDA CENTROSOMAL PROTEIN OF 76 KDA LEPOC|Ensembl=ENSLOCG00000014717.1|UniProtKB=W5NBV7 W5NBV7 PTHR15151:SF24 PROTEIN EIGER A PROLIFERATION-INDUCING LIGAND-LIKE PROTEIN-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012347.1|UniProtKB=W5N3J1 W5N3J1 PTHR10218:SF68 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus#GO:0051606;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;sensory perception of taste#GO:0050909;sensory perception of bitter taste#GO:0050913;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;signaling#GO:0023052 9+0 non-motile cilium#GO:0097731;membrane protein complex#GO:0098796;non-motile cilium#GO:0097730;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;photoreceptor inner segment#GO:0001917;cilium#GO:0005929;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 LEPOC|Ensembl=ENSLOCG00000008742.1|UniProtKB=W5MQI2 W5MQI2 PTHR13555:SF68 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015507.1|UniProtKB=W5NEM5 W5NEM5 MOV10L1 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000002284.1|UniProtKB=W5M2R7 W5M2R7 PTHR11461:SF30 SERINE PROTEASE INHIBITOR, SERPIN HEPARIN COFACTOR 2 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>HCII#P00456 LEPOC|Ensembl=ENSLOCG00000009444.1|UniProtKB=W5MT33 W5MT33 PTHR46089:SF1 ALSIN HOMOLOG ALS2 C-TERMINAL-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;transport#GO:0006810;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006394.1|UniProtKB=W5MH65 W5MH65 PTHR19143:SF45 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C DOMAIN-CONTAINING PROTEIN 1 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009189.1|UniProtKB=W5MS47 W5MS47 PTHR11143:SF7 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN L26 LIKE 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000715.1|UniProtKB=W5LXE4 W5LXE4 PTHR15092:SF44 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PARN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulatory ncRNA processing#GO:0070918;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulatory ncRNA-mediated gene silencing#GO:0031047;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000004503.1|UniProtKB=W5MAQ8 W5MAQ8 PTHR24006:SF678 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 28 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;macromolecule modification#GO:0043412;protein modification process#GO:0036211;negative regulation of cell cycle process#GO:0010948;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;response to stress#GO:0006950;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001990.1|UniProtKB=W5M1P2 W5M1P2 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000120.1|UniProtKB=W5LVK5 W5LVK5 PTHR19134:SF542 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cell junction organization#GO:0034330;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007296.1|UniProtKB=W5MKC5 W5MKC5 PTHR10845:SF155 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 18 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 LEPOC|Ensembl=ENSLOCG00000003405.1|UniProtKB=W5M6N4 W5M6N4 PTHR14453:SF70 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP9 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of cytokine-mediated signaling pathway#GO:0001961;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of response to external stimulus#GO:0032101;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;negative regulation of metabolic process#GO:0009892;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001179.1|UniProtKB=W5LYW9 W5LYW9 PTHR24230:SF55 G-PROTEIN COUPLED RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017343.1|UniProtKB=W5NLD9 W5NLD9 PTHR13205:SF15 TRANSMEMBRANE PROTEIN 15-RELATED DOLICHOL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012774.1|UniProtKB=W5N514 W5N514 PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tyrosine metabolic process#GO:0006570;organonitrogen compound catabolic process#GO:1901565;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 LEPOC|Ensembl=ENSLOCG00000007798.1|UniProtKB=W5MM61 W5MM61 ASB11 PTHR24136:SF14 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 11 positive regulation of nitrogen compound metabolic process#GO:0051173;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000002521.1|UniProtKB=W5M3K0 W5M3K0 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;heterochromatin formation#GO:0031507;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;DNA-templated DNA replication#GO:0006261;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;heterochromatin organization#GO:0070828;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;DNA strand elongation involved in DNA replication#GO:0006271;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009778.1|UniProtKB=W5MU89 W5MU89 PTHR24377:SF929 IP01015P-RELATED ZINC FINGER PROTEIN 665 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014905.1|UniProtKB=W5NCJ6 W5NCJ6 PTHR12907:SF6 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN2 cation binding#GO:0043169;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 response to hypoxia#GO:0001666;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein hydroxylation#GO:0018126;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to oxygen levels#GO:0070482;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 LEPOC|Ensembl=ENSLOCG00000010781.1|UniProtKB=W5MXV8 W5MXV8 PTHR42673:SF4 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;isomerase activity#GO:0016853;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound catabolic process#GO:1901565;glutathione metabolic process#GO:0006749;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;amide metabolic process#GO:0043603;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015181.1|UniProtKB=W5NDH3 W5NDH3 NPC1L1 PTHR45727:SF3 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC1-LIKE INTRACELLULAR CHOLESTEROL TRANSPORTER 1 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;system process#GO:0003008;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;lipid transport#GO:0006869;localization#GO:0051179;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;digestion#GO:0007586;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;multicellular organismal process#GO:0032501;lipid localization#GO:0010876 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010132.1|UniProtKB=W5MVJ0 W5MVJ0 PTHR23159:SF47 CENTROSOMAL PROTEIN 2 TRICHOHYALIN chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004657.1|UniProtKB=W5MB16 W5MB16 ZBTB21 PTHR24394:SF15 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 21 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016761.1|UniProtKB=W5NJA7 W5NJA7 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1 enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013951.1|UniProtKB=W5N987 W5N987 PTHR11844:SF26 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 4 peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000014332.1|UniProtKB=W5NAI9 W5NAI9 PTHR24390:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 710 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006052.1|UniProtKB=W5MFZ8 W5MFZ8 PTHR13337:SF2 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL tetrapyrrole binding#GO:0046906;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009001.1|UniProtKB=W5MRF3 W5MRF3 YTHDC2 PTHR18934:SF213 ATP-DEPENDENT RNA HELICASE 3'-5' RNA HELICASE YTHDC2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000003794.1|UniProtKB=W5M823 W5M823 PTHR24356:SF163 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;Ras Pathway#P04393>PDK#P04555;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;PI3 kinase pathway#P00048>PDK1#P01196;p53 pathway feedback loops 2#P04398>PDK1/2#P04656;p53 pathway#P00059>PDK1/2#P04616;Interleukin signaling pathway#P00036>PDK1/2#P00985;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;PI3 kinase pathway#P00048>P110ACT#P01177 LEPOC|Ensembl=ENSLOCG00000015429.1|UniProtKB=W5NEC6 W5NEC6 IL22RA2 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001187.1|UniProtKB=W5LYY0 W5LYY0 PTHR11949:SF26 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000012453.1|UniProtKB=W5N3X4 W5N3X4 PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010284.1|UniProtKB=W5MW39 W5MW39 PTHR18884:SF50 SEPTIN SEPTIN-10 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000009618.1|UniProtKB=W5MTR4 W5MTR4 PTHR15653:SF3 STRIATIN STRIATIN-3 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;protein phosphatase binding#GO:0019903;binding#GO:0005488 dendrite#GO:0030425;dendritic tree#GO:0097447;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000015087.1|UniProtKB=W5ND61 W5ND61 PTHR22884:SF473 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001250.1|UniProtKB=W5LZ66 W5LZ66 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004739.1|UniProtKB=W5MBG7 W5MBG7 PTHR10985:SF104 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000004338.1|UniProtKB=W5M9W9 W5M9W9 PTHR46095:SF1 ZINC FINGER PROTEIN 593 ZINC FINGER PROTEIN 593 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015203.1|UniProtKB=W5NDK7 W5NDK7 PTHR23119:SF28 DISCS LARGE DISKS LARGE HOMOLOG 3 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;developmental process#GO:0032502;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;signaling#GO:0023052;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;neuron projection#GO:0043005;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;basal part of cell#GO:0045178;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017076.1|UniProtKB=W5NKG0 W5NKG0 PTHR24023:SF918 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000006023.1|UniProtKB=W5MFZ2 W5MFZ2 PTHR13992:SF21 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770;Notch signaling pathway#P00045>CoR#P01112 LEPOC|Ensembl=ENSLOCG00000006932.1|UniProtKB=W5MJ34 W5MJ34 PTHR11567:SF202 ACID PHOSPHATASE-RELATED LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000015215.1|UniProtKB=W5NDL5 W5NDL5 PTHR21646:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007912.1|UniProtKB=W5MMK1 W5MMK1 PTHR10654:SF20 CAS SCAFFOLDING PROTEIN ENHANCER OF FILAMENTATION 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008403.1|UniProtKB=W5MPA7 W5MPA7 PTHR12241:SF147 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL7 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001930.1|UniProtKB=W5M1H4 W5M1H4 PTHR31885:SF6 GH04784P GH04784P hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008985.1|UniProtKB=W5MRE0 W5MRE0 PTHR10742:SF377 FLAVIN MONOAMINE OXIDASE SPERMINE OXIDASE-LIKE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015143.1|UniProtKB=W5NDD0 W5NDD0 DUSP26 PTHR45682:SF8 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 26 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000008773.1|UniProtKB=W5MQL6 W5MQL6 PTHR21454:SF31 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000003555.1|UniProtKB=W5M749 W5M749 PTHR23136:SF8 TAX1-BINDING PROTEIN 3-RELATED ST6 N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 3 LEPOC|Ensembl=ENSLOCG00000012297.1|UniProtKB=W5N3C4 W5N3C4 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 lyase activity#GO:0016829;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;peptide catabolic process#GO:0043171;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012429.1|UniProtKB=W5N3U1 W5N3U1 PTHR46990:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006158.1|UniProtKB=W5MGC8 W5MGC8 PTHR15039:SF11 DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;mannosyltransferase complex#GO:0031501 LEPOC|Ensembl=ENSLOCG00000009163.1|UniProtKB=W5MS10 W5MS10 PTHR24340:SF28 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005976.1|UniProtKB=W5MFR6 W5MFR6 PTHR15672:SF13 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015154.1|UniProtKB=W5NDE2 W5NDE2 PTHR11036:SF80 SEMAPHORIN SEMAPHORIN-7A molecular function activator activity#GO:0140677;integrin binding#GO:0005178;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;integrin-mediated signaling pathway#GO:0007229;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of defense response#GO:0031347;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;generation of neurons#GO:0048699;cell migration#GO:0016477 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012610.1|UniProtKB=W5N4G1 W5N4G1 PTHR13419:SF2 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 5 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002831.1|UniProtKB=W5M4M4 W5M4M4 PTHR46883:SF1 BARDET-BIEDL SYNDROME 12 PROTEIN BARDET-BIEDL SYNDROME 12 PROTEIN LEPOC|Ensembl=ENSLOCG00000008289.1|UniProtKB=W5MNV8 W5MNV8 PTHR10165:SF17 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010050.1|UniProtKB=W5MV82 W5MV82 PTHR43622:SF3 3-DEHYDROQUINATE SYNTHASE 2-EPI-5-EPI-VALIOLONE SYNTHASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000011146.1|UniProtKB=W5MZ88 W5MZ88 PTHR18964:SF149 ROK (REPRESSOR, ORF, KINASE) FAMILY BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000011795.1|UniProtKB=W5N1K6 W5N1K6 PTHR14650:SF1 PROLYL HYDROXYLASE-RELATED 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006093.1|UniProtKB=W5MG53 W5MG53 SPIDR PTHR34347:SF1 DNA REPAIR-SCAFFOLDING PROTEIN SPIDR DNA REPAIR-SCAFFOLDING PROTEIN DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;recombinational repair#GO:0000725;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015340.1|UniProtKB=W5NE18 W5NE18 PTHR15352:SF3 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003163.1|UniProtKB=W5M5U8 W5M5U8 PTHR11599:SF12 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000007213.1|UniProtKB=W5MK21 W5MK21 PTHR12558:SF36 CELL DIVISION CYCLE 16,23,27 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 cell division#GO:0051301;regulation of mitotic nuclear division#GO:0007088;positive regulation of organelle organization#GO:0010638;regulation of chromosome segregation#GO:0051983;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;protein ubiquitination#GO:0016567;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;positive regulation of mitotic nuclear division#GO:0045840;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017854.1|UniProtKB=W5NMU8 W5NMU8 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006077.1|UniProtKB=W5MG31 W5MG31 PTHR11006:SF51 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003513.1|UniProtKB=W5M717 W5M717 PTHR13992:SF5 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770 LEPOC|Ensembl=ENSLOCG00000004325.1|UniProtKB=W5M9V9 W5M9V9 PTHR10024:SF180 SYNAPTOTAGMIN SYNAPTOTAGMIN-9 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017075.1|UniProtKB=W5NKE3 W5NKE3 PTHR10426:SF20 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000002559.1|UniProtKB=W5M3P5 W5M3P5 PTHR47139:SF4 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 ISOFORM X1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004448.1|UniProtKB=W5MAA2 W5MAA2 PAFAH1B1 PTHR44129:SF13 WD REPEAT-CONTAINING PROTEIN POP1 LISSENCEPHALY-1 HOMOLOG A-RELATED LEPOC|Ensembl=ENSLOCG00000013706.1|UniProtKB=W5N8F1 W5N8F1 PTHR13865:SF25 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cellular localization#GO:0051641;macromolecule localization#GO:0033036;epithelium development#GO:0060429;system process#GO:0003008;developmental process#GO:0032502;cell differentiation#GO:0030154;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;anatomical structure homeostasis#GO:0060249;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;homeostatic process#GO:0042592;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;circulatory system process#GO:0003013;protein localization#GO:0008104;cell development#GO:0048468;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446 anchoring junction#GO:0070161;tight junction#GO:0070160;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000016543.1|UniProtKB=W5NIH1 W5NIH1 PTHR21711:SF0 MITOCHONDRIAL INNER MEMBRANE PROTEASE MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial protein processing#GO:0034982;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;proteolysis#GO:0006508;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011991.1|UniProtKB=W5N285 W5N285 PTHR28604:SF1 FAMILY NOT NAMED PROLINE-RICH PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000015854.1|UniProtKB=W5NFW4 W5NFW4 PTHR46461:SF1 KELCH DOMAIN-CONTAINING PROTEIN 3 KELCH DOMAIN-CONTAINING PROTEIN 3 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002485.1|UniProtKB=W5M3H1 W5M3H1 CCNO PTHR10177:SF401 CYCLINS CYCLIN-O protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000010099.1|UniProtKB=W5MVE7 W5MVE7 PTHR36866:SF1 CHROMOSOME 4 OPEN READING FRAME 50 GENE 1043-RELATED LEPOC|Ensembl=ENSLOCG00000018048.1|UniProtKB=W5NNE0 W5NNE0 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011814.1|UniProtKB=W5N1N0 W5N1N0 PRLR PTHR23036:SF86 CYTOKINE RECEPTOR PROLACTIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PRLR#P06822 LEPOC|Ensembl=ENSLOCG00000008584.1|UniProtKB=W5MPY4 W5MPY4 PTHR43107:SF7 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 1 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;import into cell#GO:0098657;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004428.1|UniProtKB=W5MA80 W5MA80 PTHR13962:SF17 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005751.1|UniProtKB=W5MEZ1 W5MEZ1 PTHR10698:SF0 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006710.1|UniProtKB=W5MI98 W5MI98 TMPRSS13 PTHR24253:SF55 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013199.1|UniProtKB=W5N6K2 W5N6K2 RBPMS PTHR10501:SF25 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA-BINDING PROTEIN WITH MULTIPLE SPLICING nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011264.1|UniProtKB=W5MZN8 W5MZN8 KLHL1 PTHR24412:SF75 KELCH PROTEIN KELCH-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009192.1|UniProtKB=W5MS48 W5MS48 PTHR11767:SF3 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 13 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014049.1|UniProtKB=W5N9K7 W5N9K7 PTHR11878:SF7 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 3 calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;axon#GO:0030424;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004230.1|UniProtKB=W5M9J6 W5M9J6 PTHR23136:SF13 TAX1-BINDING PROTEIN 3-RELATED ST6 N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 4 LEPOC|Ensembl=ENSLOCG00000007199.1|UniProtKB=W5MK18 W5MK18 PTHR23176:SF107 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 12 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000007775.1|UniProtKB=W5MM33 W5MM33 PTHR12757:SF4 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000018.1|UniProtKB=W5LV62 W5LV62 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014735.1|UniProtKB=W5NBY7 W5NBY7 PTHR24346:SF28 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009549.1|UniProtKB=W5MTH4 W5MTH4 PTHR21377:SF1 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210A cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006513.1|UniProtKB=W5MHL4 W5MHL4 PTHR12308:SF16 ANOCTAMIN ANOCTAMIN-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004493.1|UniProtKB=W5MAG3 W5MAG3 PTHR21444:SF14 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 LEPOC|Ensembl=ENSLOCG00000012421.1|UniProtKB=W5N3T3 W5N3T3 PTHR33820:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 COILED-COIL DOMAIN-CONTAINING PROTEIN 17-LIKE LEPOC|Ensembl=ENSLOCG00000014790.1|UniProtKB=W5NC53 W5NC53 PTHR11890:SF10 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER X-LINKED INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011420.1|UniProtKB=W5N079 W5N079 KLHDC1 PTHR46228:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017987.1|UniProtKB=W5NN79 W5NN79 PTHR11394:SF148 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003490.1|UniProtKB=W5M6Y3 W5M6Y3 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000017689.1|UniProtKB=W5NMD5 W5NMD5 PTHR40472:SF7 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN PROTEIN RAPUNZEL LEPOC|Ensembl=ENSLOCG00000014331.1|UniProtKB=W5NAI8 W5NAI8 SHROOM4 PTHR15012:SF35 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012003.1|UniProtKB=W5N2A5 W5N2A5 PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005070.1|UniProtKB=W5MCJ5 W5MCJ5 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001269.1|UniProtKB=W5LZ84 W5LZ84 PTHR47027:SF26 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004709.1|UniProtKB=W5MBB0 W5MBB0 PTHR45614:SF9 MYB PROTEIN-RELATED MYB-RELATED PROTEIN A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;mitotic cell cycle#GO:0000278;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002805.1|UniProtKB=W5M4L0 W5M4L0 PTHR10896:SF19 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008420.1|UniProtKB=W5MPE5 W5MPE5 PTHR11827:SF58 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;chloride transmembrane transport#GO:1902476;sodium ion homeostasis#GO:0055078;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;apical part of cell#GO:0045177 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013699.1|UniProtKB=W5N8D4 W5N8D4 PTHR21275:SF1 RWD DOMAIN-CONTAINING PROTEIN 4 RWD DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000000826.1|UniProtKB=W5LXR5 W5LXR5 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000013128.1|UniProtKB=W5N6C3 W5N6C3 PTHR24092:SF80 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IM-RELATED ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004041.1|UniProtKB=W5M8W6 W5M8W6 PTHR37457:SF2 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013445.1|UniProtKB=W5N7G9 W5N7G9 PTHR10792:SF8 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001842.1|UniProtKB=W5M195 W5M195 PTHR24370:SF10 OPTICIN LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000001920.1|UniProtKB=W5M1I5 W5M1I5 PTHR46501:SF2 MYOMEGALIN MYOMEGALIN regulation of microtubule-based process#GO:0032886;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015486.1|UniProtKB=W5NEK2 W5NEK2 PTHR32194:SF2 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA TYPE-1 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000010154.1|UniProtKB=W5MVM4 W5MVM4 PTHR31770:SF2 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000013012.1|UniProtKB=W5N5X2 W5N5X2 PTHR24082:SF42 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;intracellular receptor signaling pathway#GO:0030522;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009440.1|UniProtKB=W5MT20 W5MT20 PTHR11564:SF5 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002911.1|UniProtKB=W5M4W1 W5M4W1 ZBTB26 PTHR24399:SF14 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003019.1|UniProtKB=W5M5A2 W5M5A2 RNF43 PTHR16200:SF2 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE RNF43 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of cell communication#GO:0010646;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008355.1|UniProtKB=W5MP55 W5MP55 PTHR24092:SF81 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VA ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003859.1|UniProtKB=W5M8A0 W5M8A0 PTHR22897:SF7 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 2 protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;disulfide oxidoreductase activity#GO:0015036;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013627.1|UniProtKB=W5N842 W5N842 ASB5 PTHR24136:SF18 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 5 positive regulation of nitrogen compound metabolic process#GO:0051173;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000011710.1|UniProtKB=W5N184 W5N184 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR transporter activity#GO:0005215;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule localization#GO:0033036;carbohydrate derivative catabolic process#GO:1901136;transport#GO:0006810;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;lipid transport#GO:0006869;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;localization#GO:0051179;organic substance transport#GO:0071702;membrane lipid metabolic process#GO:0006643;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001906.1|UniProtKB=W5M1E5 W5M1E5 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016025.1|UniProtKB=W5NGH8 W5NGH8 PTHR16434:SF2 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 ETAA1 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 LEPOC|Ensembl=ENSLOCG00000013872.1|UniProtKB=W5N900 W5N900 PTHR24393:SF34 ZINC FINGER PROTEIN PR_SET DOMAIN 13 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001861.1|UniProtKB=W5M1B6 W5M1B6 PTHR47678:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 31 TETRATRICOPEPTIDE REPEAT PROTEIN 31 LEPOC|Ensembl=ENSLOCG00000017860.1|UniProtKB=W5NMV4 W5NMV4 PTHR11767:SF6 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007534.1|UniProtKB=W5ML79 W5ML79 PTHR24180:SF58 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 49 kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000012112.1|UniProtKB=W5N2P2 W5N2P2 PTHR11588:SF88 TUBULIN TUBULIN BETA-6 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 LEPOC|Ensembl=ENSLOCG00000010088.1|UniProtKB=W5MVD0 W5MVD0 PTHR14320:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 LEPOC|Ensembl=ENSLOCG00000017926.1|UniProtKB=W5NN20 W5NN20 TMEM215 PTHR31922:SF2 TRANSMEMBRANE PROTEIN 215 TRANSMEMBRANE PROTEIN 215 LEPOC|Ensembl=ENSLOCG00000005570.1|UniProtKB=W5MED5 W5MED5 PTHR11255:SF43 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ZETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Gonadotropin-releasing hormone receptor pathway#P06664>DGK-zeta#P06790 LEPOC|Ensembl=ENSLOCG00000016036.1|UniProtKB=W5NGJ2 W5NGJ2 PTHR10188:SF16 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE-LIKE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009116.1|UniProtKB=W5MRV8 W5MRV8 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification process#GO:0036211;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015103.1|UniProtKB=W5ND77 W5ND77 PTHR21016:SF4 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000008624.1|UniProtKB=W5MQ28 W5MQ28 PTHR11375:SF5 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;histone binding#GO:0042393;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012359.1|UniProtKB=W5N3K6 W5N3K6 CNTD1 PTHR21615:SF2 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000005523.1|UniProtKB=W5ME60 W5ME60 PTHR22874:SF1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;mitophagy#GO:0000423;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008438.1|UniProtKB=W5MPF2 W5MPF2 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 LEPOC|Ensembl=ENSLOCG00000012124.1|UniProtKB=W5N2Q8 W5N2Q8 PTHR31728:SF2 ABRAXAS FAMILY MEMBER BRCA1-A COMPLEX SUBUNIT ABRAXAS 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;macromolecule modification#GO:0043412;nuclear division#GO:0000280;protein K63-linked deubiquitination#GO:0070536;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;establishment of organelle localization#GO:0051656;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000460.1|UniProtKB=W5LWJ5 W5LWJ5 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015140.1|UniProtKB=W5NDC4 W5NDC4 PTHR11315:SF1 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE FOLATE GAMMA-GLUTAMYL HYDROLASE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008418.1|UniProtKB=W5MPC9 W5MPC9 KCNH7 PTHR10217:SF466 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 7 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015164.1|UniProtKB=W5NDF6 W5NDF6 PTHR22826:SF146 RHO GUANINE EXCHANGE FACTOR-RELATED PROTO-ONCOGENE DBL nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;dendrite development#GO:0016358;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004130.1|UniProtKB=W5M991 W5M991 PTHR45876:SF6 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39-LIKE nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017126.1|UniProtKB=W5NKK4 W5NKK4 PTHR23316:SF10 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-6 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002371.1|UniProtKB=W5M319 W5M319 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015991.1|UniProtKB=W5NGD2 W5NGD2 PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A LEPOC|Ensembl=ENSLOCG00000007460.1|UniProtKB=W5ML04 W5ML04 PTHR45785:SF2 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000010119.1|UniProtKB=W5MVH9 W5MVH9 PTHR46515:SF1 TATA ELEMENT MODULATORY FACTOR TMF1 TATA ELEMENT MODULATORY FACTOR cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013472.1|UniProtKB=W5N7K1 W5N7K1 PTHR45891:SF2 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016607.1|UniProtKB=W5NIQ5 W5NIQ5 PTHR12474:SF3 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-1 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of metabolic process#GO:0009893;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;positive regulation of macroautophagy#GO:0016239;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012046.1|UniProtKB=W5N2G1 W5N2G1 ATXN7L3 PTHR46367:SF1 ATAXIN-7-LIKE PROTEIN 3 ATAXIN-7-LIKE PROTEIN 3 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000012615.1|UniProtKB=W5N4H0 W5N4H0 LZTS2 PTHR19354:SF4 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 2-RELATED regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000000447.1|UniProtKB=W5LWI1 W5LWI1 PTHR23266:SF403 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008302.1|UniProtKB=W5MNX8 W5MNX8 PTHR19232:SF1 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000013933.1|UniProtKB=W5N971 W5N971 PTHR10782:SF11 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like protein ligase activity#GO:0061659;SUMO ligase activity#GO:0061665;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein sumoylation#GO:0016925;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 LEPOC|Ensembl=ENSLOCG00000004072.1|UniProtKB=W5M901 W5M901 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003054.1|UniProtKB=W5M5D3 W5M5D3 C11orf58 PTHR22175:SF0 SMALL ACIDIC PROTEIN-RELATED SMALL ACIDIC PROTEIN LEPOC|Ensembl=ENSLOCG00000009663.1|UniProtKB=W5MTW8 W5MTW8 PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001795.1|UniProtKB=W5M124 W5M124 PTHR15367:SF3 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000014408.1|UniProtKB=W5NAT5 W5NAT5 PTHR11945:SF637 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2A cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 LEPOC|Ensembl=ENSLOCG00000016651.1|UniProtKB=W5NIV9 W5NIV9 PTHR46763:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015855.1|UniProtKB=W5NFX0 W5NFX0 PTHR10285:SF69 URIDINE KINASE URIDINE-CYTIDINE KINASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000017501.1|UniProtKB=W5NLU7 W5NLU7 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016610.1|UniProtKB=W5NIR1 W5NIR1 PTHR12673:SF98 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;filopodium assembly#GO:0046847;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015872.1|UniProtKB=W5NFY2 W5NFY2 PTHR21074:SF0 IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014130.1|UniProtKB=W5N9U6 W5N9U6 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017939.1|UniProtKB=W5NN33 W5NN33 ASCL5 PTHR23349:SF108 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010347.1|UniProtKB=W5MWB6 W5MWB6 PTHR15444:SF4 SECRETED PHOSPHOPROTEIN 24 SECRETED PHOSPHOPROTEIN 24 LEPOC|Ensembl=ENSLOCG00000010531.1|UniProtKB=W5MWZ8 W5MWZ8 PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011459.1|UniProtKB=W5N0B8 W5N0B8 PTHR46845:SF2 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR 3 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000016774.1|UniProtKB=W5NJC3 W5NJC3 PTHR23339:SF93 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE ZGC:77752 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013550.1|UniProtKB=W5N7U7 W5N7U7 PTHR43205:SF5 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001125.1|UniProtKB=W5LYQ9 W5LYQ9 IL12B PTHR48485:SF3 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT BETA LEPOC|Ensembl=ENSLOCG00000016830.1|UniProtKB=W5NJJ2 W5NJJ2 PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE AND EMI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013910.1|UniProtKB=W5N950 W5N950 PTHR45620:SF29 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013816.1|UniProtKB=W5N8S8 W5N8S8 PTHR15197:SF0 COILIN P80 COILIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007690.1|UniProtKB=W5MLT2 W5MLT2 PTHR22776:SF9 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PLASMOLIPIN structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013625.1|UniProtKB=W5N838 W5N838 PTHR12509:SF8 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000016049.1|UniProtKB=W5NGL1 W5NGL1 PTHR11346:SF98 GALECTIN GALECTIN-RELATED PROTEIN carbohydrate binding#GO:0030246;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000012835.1|UniProtKB=W5N587 W5N587 PTHR24027:SF322 CADHERIN-23 CADHERIN-6 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;cell junction assembly#GO:0034329;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000003230.1|UniProtKB=W5M608 W5M608 PTHR24061:SF1 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010236.1|UniProtKB=W5MVX5 W5MVX5 PTHR10562:SF14 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>Sumo-1 ligase#P04635 LEPOC|Ensembl=ENSLOCG00000000917.1|UniProtKB=W5LY16 W5LY16 PTHR14819:SF9 GTP-BINDING UP-REGULATOR OF CELL PROLIFERATION-LIKE LEPOC|Ensembl=ENSLOCG00000006879.1|UniProtKB=W5MIW4 W5MIW4 PTHR12549:SF6 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 2C-RELATED histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;histone demethylase activity#GO:0032452;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;demethylase activity#GO:0032451;molecular adaptor activity#GO:0060090;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000013205.1|UniProtKB=W5N6K4 W5N6K4 HTD2 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000002939.1|UniProtKB=W5M510 W5M510 PTHR15268:SF16 THRAP3/BCLAF1 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN 3 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010863.1|UniProtKB=W5MY58 W5MY58 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012444.1|UniProtKB=W5N3V8 W5N3V8 HAND1 PTHR23349:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;circulatory system development#GO:0072359;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009390.1|UniProtKB=W5MSU6 W5MSU6 PTHR10835:SF0 SQUALENE MONOOXYGENASE SQUALENE MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 Cholesterol biosynthesis#P00014>Squalene monooxygenas#P00494 LEPOC|Ensembl=ENSLOCG00000003412.1|UniProtKB=W5M6N1 W5M6N1 STARD6 PTHR46374:SF2 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000014078.1|UniProtKB=W5N9P2 W5N9P2 PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S cellular localization#GO:0051641;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000013139.1|UniProtKB=W5N6C5 W5N6C5 PTHR13009:SF22 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 LD43819P molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;positive regulation of molecular function#GO:0044093;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011570.1|UniProtKB=W5N0R0 W5N0R0 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014935.1|UniProtKB=W5NCN0 W5NCN0 PTHR25462:SF302 BONUS, ISOFORM C-RELATED PROTEIN PML transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;response to biotic stimulus#GO:0009607;apoptotic process#GO:0006915;cell death#GO:0008219;innate immune response#GO:0045087;defense response to virus#GO:0051607;intracellular signal transduction#GO:0035556;defense response#GO:0006952;signaling#GO:0023052;cellular response to stimulus#GO:0051716;immune response#GO:0006955;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular process#GO:0009987;defense response to symbiont#GO:0140546;response to external stimulus#GO:0009605;intrinsic apoptotic signaling pathway#GO:0097193;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 p53 pathway#P00059>PML#G04701;p53 pathway#P00059>PML#P04618 LEPOC|Ensembl=ENSLOCG00000008692.1|UniProtKB=W5MQB5 W5MQB5 PTHR32012:SF0 TRANSMEMBRANE PROTEIN 182-RELATED TRANSMEMBRANE PROTEIN 182 LEPOC|Ensembl=ENSLOCG00000015839.1|UniProtKB=W5NFT8 W5NFT8 PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016338.1|UniProtKB=W5NHR0 W5NHR0 PTHR10812:SF14 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000004284.1|UniProtKB=W5M9S4 W5M9S4 PTHR31743:SF1 TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN TCPC4AP SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017833.1|UniProtKB=W5NMS7 W5NMS7 PTHR11079:SF156 CYTOSINE DEAMINASE FAMILY MEMBER INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;tRNA-specific adenosine deaminase activity#GO:0008251;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017785.1|UniProtKB=W5NMN0 W5NMN0 PTHR14499:SF9 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007363.1|UniProtKB=W5MKP6 W5MKP6 PTHR45739:SF1 MATRIX PROTEIN, PUTATIVE-RELATED EXTRACELLULAR MATRIX ORGANIZING PROTEIN FRAS1 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013822.1|UniProtKB=W5N8U7 W5N8U7 PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657 nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;spindle elongation#GO:0051231;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008849.1|UniProtKB=W5MQV7 W5MQV7 DMXL1 PTHR13950:SF12 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 1 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015407.1|UniProtKB=W5NEA8 W5NEA8 PTHR22891:SF188 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;male gamete generation#GO:0048232;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;spermatogenesis#GO:0007283;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;regulatory ncRNA-mediated gene silencing#GO:0031047;gamete generation#GO:0007276;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;negative regulation of macromolecule biosynthetic process#GO:0010558;piRNA processing#GO:0034587;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000015503.1|UniProtKB=W5NEM0 W5NEM0 PANX PTHR15759:SF7 PANNEXIN PANNEXIN-2 wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009087.1|UniProtKB=W5MRS6 W5MRS6 PTHR12761:SF1 HERMANSKY-PUDLAK SYNDROME PROTEIN 1 BLOC-3 COMPLEX MEMBER HPS1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000008570.1|UniProtKB=W5MPX1 W5MPX1 PTHR43521:SF1 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000014778.1|UniProtKB=W5NC42 W5NC42 PTHR14944:SF4 RPA-RELATED PROTEIN RADX RPA1 RELATED SINGLE STRANDED DNA BINDING PROTEIN, X-LINKED LEPOC|Ensembl=ENSLOCG00000008873.1|UniProtKB=W5MQZ5 W5MQZ5 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003776.1|UniProtKB=W5M7Z3 W5M7Z3 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000015857.1|UniProtKB=W5NFW3 W5NFW3 SPAM1 PTHR11769:SF20 HYALURONIDASE HYALURONIDASE PH-20 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;macromolecule catabolic process#GO:0009057;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008967.1|UniProtKB=W5MRB4 W5MRB4 PTHR47678:SF2 TETRATRICOPEPTIDE REPEAT PROTEIN 31 TETRATRICOPEPTIDE REPEAT PROTEIN 31 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000015410.1|UniProtKB=W5NEA3 W5NEA3 PTHR12378:SF6 DESUMOYLATING ISOPEPTIDASE DEUBIQUITINASE DESI2 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008883.1|UniProtKB=W5MR07 W5MR07 PTHR11764:SF20 TERPENE CYCLASE/MUTASE FAMILY MEMBER LANOSTEROL SYNTHASE cyclase#PC00079;lyase#PC00144 Cholesterol biosynthesis#P00014>Anosterol synthase#P00497 LEPOC|Ensembl=ENSLOCG00000018067.1|UniProtKB=W5NNF9 W5NNF9 KCNA10 PTHR11537:SF44 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 10 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000018329.1|UniProtKB=W5NP71 W5NP71 PTHR23401:SF1 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209 neuron projection guidance#GO:0097485;head development#GO:0060322;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;distal axon#GO:0150034;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000008439.1|UniProtKB=W5MPF3 W5MPF3 SLC66A2 PTHR14856:SF10 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 endosomal transport#GO:0016197;cellular localization#GO:0051641;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000002690.1|UniProtKB=W5M454 W5M454 PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR LEPOC|Ensembl=ENSLOCG00000017344.1|UniProtKB=W5NLE0 W5NLE0 PTHR25464:SF3 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE TRIM32 LEPOC|Ensembl=ENSLOCG00000009068.1|UniProtKB=W5MRN8 W5MRN8 PTHR47140:SF1 MAP3K7 C-TERMINAL-LIKE PROTEIN MAP3K7 C-TERMINAL-LIKE PROTEIN cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Ras Pathway#P04393>TAK#P04575;TGF-beta signaling pathway#P00052>TAK#P01285 LEPOC|Ensembl=ENSLOCG00000000943.1|UniProtKB=W5LY47 W5LY47 PTHR12941:SF13 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000002417.1|UniProtKB=W5M396 W5M396 PTHR11036:SF39 SEMAPHORIN SEMAPHORIN-5B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;axon guidance#GO:0007411;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell communication#GO:0007154;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013373.1|UniProtKB=W5N777 W5N777 PTHR13363:SF5 RING FINGER AND SRY DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF123 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015422.1|UniProtKB=W5NEC0 W5NEC0 PTHR12752:SF3 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 5 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008182.1|UniProtKB=W5MNH5 W5MNH5 PTHR24418:SF231 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SYK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;macrophage activation#GO:0042116;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;neutrophil activation#GO:0042119;macrophage activation involved in immune response#GO:0002281;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune effector process#GO:0002252;leukocyte activation#GO:0045321;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;cell activation involved in immune response#GO:0002263;myeloid leukocyte activation#GO:0002274;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;leukocyte activation involved in immune response#GO:0002366;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell adhesion#GO:0045785;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of cell adhesion mediated by integrin#GO:0033628 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Syk#P00382 LEPOC|Ensembl=ENSLOCG00000009434.1|UniProtKB=W5MT10 W5MT10 WASHC2C PTHR21669:SF38 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS WASH COMPLEX SUBUNIT 2A-RELATED protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013555.1|UniProtKB=W5N7W0 W5N7W0 PTHR16089:SF24 REST COREPRESSOR COREST PROTEIN-RELATED MITOTIC DEACETYLASE-ASSOCIATED SANT DOMAIN PROTEIN molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006489.1|UniProtKB=W5MHI0 W5MHI0 PTHR15494:SF0 CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;sperm flagellum#GO:0036126 LEPOC|Ensembl=ENSLOCG00000001598.1|UniProtKB=W5M0D0 W5M0D0 NMI PTHR15225:SF4 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN N-MYC-INTERACTOR cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000017589.1|UniProtKB=W5NM35 W5NM35 PTHR21465:SF2 ZINC FINGER PROTEIN 469 ZINC FINGER PROTEIN 469 LEPOC|Ensembl=ENSLOCG00000003623.1|UniProtKB=W5M7D8 W5M7D8 PTHR35268:SF1 PROTEIN CCSMST1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 4 LEPOC|Ensembl=ENSLOCG00000016018.1|UniProtKB=W5NGH2 W5NGH2 PTHR11848:SF226 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;regionalization#GO:0003002;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000014746.1|UniProtKB=W5NBZ9 W5NBZ9 PTHR46576:SF1 BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000013377.1|UniProtKB=W5N782 W5N782 PTHR13020:SF9 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN negative regulation of gene expression#GO:0010629;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010499.1|UniProtKB=W5MWW3 W5MWW3 PTHR45755:SF1 FAMILY NOT NAMED PROTON-COUPLED ZINC ANTIPORTER SLC30A5 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011635.1|UniProtKB=W5N0Y6 W5N0Y6 KAZALD1 PTHR14186:SF26 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL TYPE SERINE PEPTIDASE INHIBITOR DOMAIN 1 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000011499.1|UniProtKB=W5N0H9 W5N0H9 PTHR10799:SF541 SNF2/RAD54 HELICASE FAMILY GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2-RELATED ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;protein binding#GO:0005515;transcription factor binding#GO:0008134 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000001614.1|UniProtKB=W5M0E8 W5M0E8 PTHR16515:SF37 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 2 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006699.1|UniProtKB=W5MI84 W5MI84 PTHR19139:SF39 AQUAPORIN TRANSPORTER LENS FIBER MAJOR INTRINSIC PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016231.1|UniProtKB=W5NHA5 W5NHA5 TSPAN8 PTHR19282:SF380 TETRASPANIN TETRASPANIN-8 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004491.1|UniProtKB=W5MAJ4 W5MAJ4 PTHR13402:SF11 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16B localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;protein localization to endoplasmic reticulum#GO:0070972;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000006702.1|UniProtKB=W5MI87 W5MI87 PTHR23255:SF96 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;phosphate-containing compound metabolic process#GO:0006796;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;system development#GO:0048731;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000006240.1|UniProtKB=W5MGN0 W5MGN0 PTHR24085:SF7 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007456.1|UniProtKB=W5MKZ6 W5MKZ6 PTHR13817:SF44 TITIN FIBRONECTIN TYPE III DOMAIN CONTAINING 3B structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000000527.1|UniProtKB=W5LWS2 W5LWS2 EDN4 PTHR13874:SF12 ENDOTHELIN ENDOTHELIN-3A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;positive regulation of catalytic activity#GO:0043085;system process#GO:0003008;positive regulation of molecular function#GO:0044093;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;regulation of systemic arterial blood pressure#GO:0003073;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;circulatory system process#GO:0003013;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of blood pressure#GO:0008217;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular monoatomic ion homeostasis#GO:0006873;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000003980.1|UniProtKB=W5M8P7 W5M8P7 PTHR31075:SF3 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000017000.1|UniProtKB=W5NK55 W5NK55 PTHR12876:SF11 N4BP1-RELATED RIBONUCLEASE ZC3H12D-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004612.1|UniProtKB=W5MAZ0 W5MAZ0 PTHR24027:SF300 CADHERIN-23 CADHERIN-15 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000000445.1|UniProtKB=W5LWI2 W5LWI2 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000283.1|UniProtKB=W5LW02 W5LW02 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008194.1|UniProtKB=W5MNI8 W5MNI8 PTHR45710:SF31 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017369.1|UniProtKB=W5NLG5 W5NLG5 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006647.1|UniProtKB=W5MI21 W5MI21 PTHR10782:SF12 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like protein ligase activity#GO:0061659;SUMO ligase activity#GO:0061665;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein sumoylation#GO:0016925;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 LEPOC|Ensembl=ENSLOCG00000009251.1|UniProtKB=W5MSC8 W5MSC8 PTHR22897:SF6 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 1 protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;disulfide oxidoreductase activity#GO:0015036;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005971.1|UniProtKB=W5MFQ7 W5MFQ7 PTHR16208:SF1 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTAPHILIN cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000005945.1|UniProtKB=W5MFQ8 W5MFQ8 PTHR10554:SF2 SYNTROPHIN GAMMA-1-SYNTROPHIN membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011745.1|UniProtKB=W5N1D1 W5N1D1 PTHR15360:SF2 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 LEPOC|Ensembl=ENSLOCG00000002670.1|UniProtKB=W5M427 W5M427 LEPROTL1 PTHR12050:SF4 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR OVERLAPPING TRANSCRIPT-LIKE 1 endosomal transport#GO:0016197;regulation of cell communication#GO:0010646;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;vacuolar transport#GO:0007034;transport#GO:0006810;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;endosome transport via multivesicular body sorting pathway#GO:0032509;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017540.1|UniProtKB=W5NLY6 W5NLY6 PTHR46291:SF9 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C-LIKE LEPOC|Ensembl=ENSLOCG00000000246.1|UniProtKB=W5LVX1 W5LVX1 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000015443.1|UniProtKB=W5NEE9 W5NEE9 PTHR12751:SF5 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000009268.1|UniProtKB=W5MSE3 W5MSE3 PTHR31919:SF1 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014001.1|UniProtKB=W5N9F0 W5N9F0 PTHR24073:SF653 DRAB5-RELATED RAS-RELATED PROTEIN RAB-43 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;vacuole organization#GO:0007033;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010413.1|UniProtKB=W5MWL3 W5MWL3 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 LEPOC|Ensembl=ENSLOCG00000010077.1|UniProtKB=W5MVC3 W5MVC3 PTHR11647:SF54 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 LEPOC|Ensembl=ENSLOCG00000008653.1|UniProtKB=W5MQ65 W5MQ65 PTHR46916:SF1 TRANSMEMBRANE PROTEIN 205 TRANSMEMBRANE PROTEIN 205 LEPOC|Ensembl=ENSLOCG00000018215.1|UniProtKB=W5NNV7 W5NNV7 PTHR26451:SF991 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006450.1|UniProtKB=W5MHD1 W5MHD1 PTHR12460:SF40 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000012536.1|UniProtKB=W5N487 W5N487 SYNPO2 PTHR24217:SF9 PUTATIVE-RELATED SYNAPTOPODIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;positive regulation of actin filament bundle assembly#GO:0032233;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament bundle assembly#GO:0032231;positive regulation of biological process#GO:0048518 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000018146.1|UniProtKB=W5NNN8 W5NNN8 PTHR24366:SF160 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS SI:CH211-191D15.2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000017539.1|UniProtKB=W5NLY5 W5NLY5 PTHR11829:SF215 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004106.1|UniProtKB=W5M975 W5M975 PTHR43807:SF14 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 1 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015494.1|UniProtKB=W5NEL2 W5NEL2 PTHR10615:SF174 HISTONE ACETYLTRANSFERASE PHD FINGER PROTEIN 10 histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;N-acyltransferase activity#GO:0016410;molecular adaptor activity#GO:0060090;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007516.1|UniProtKB=W5ML66 W5ML66 PTHR10139:SF1 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;sexual reproduction#GO:0019953;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;negative regulation of mitotic cell cycle phase transition#GO:1901991;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;meiotic DNA double-strand break formation#GO:0042138;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015978.1|UniProtKB=W5NGB3 W5NGB3 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006003.1|UniProtKB=W5MFU5 W5MFU5 PTHR31848:SF0 FAMILY NOT NAMED REFILIN-A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;actin filament bundle organization#GO:0061572;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011711.1|UniProtKB=W5N185 W5N185 GAR1 PTHR23237:SF6 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010935.1|UniProtKB=W5MYF1 W5MYF1 PTHR24161:SF124 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED TRANSIENT RECEPTOR POTENTIAL CHANNEL PYREXIA protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003319.1|UniProtKB=W5M6E1 W5M6E1 PTHR13817:SF85 TITIN DCC NETRIN 1 RECEPTOR structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005571.1|UniProtKB=W5MEB5 W5MEB5 LPAR3 PTHR22750:SF21 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005697.1|UniProtKB=W5MER6 W5MER6 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;nucleic acid transport#GO:0050657;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;centrosome duplication#GO:0051298;biosynthetic process#GO:0009058;chromosome segregation#GO:0007059;RNA localization#GO:0006403;organic substance transport#GO:0071702;establishment of localization#GO:0051234;RNA transport#GO:0050658;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nuclear export#GO:0051168;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription export complex 2#GO:0070390;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;spindle#GO:0005819 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007466.1|UniProtKB=W5ML01 W5ML01 ZNF423 PTHR24409:SF306 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 423 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004265.1|UniProtKB=W5M9P2 W5M9P2 PTHR11941:SF54 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydratase#PC00120 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 LEPOC|Ensembl=ENSLOCG00000010017.1|UniProtKB=W5MV57 W5MV57 PTHR45799:SF6 RETICULON-LIKE PROTEIN RETICULON head development#GO:0060322;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;endoplasmic reticulum organization#GO:0007029;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;endomembrane system organization#GO:0010256;brain development#GO:0007420;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell junction#GO:0030054;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000000275.1|UniProtKB=W5LVZ3 W5LVZ3 PTHR45695:SF8 LEUCOKININ RECEPTOR-RELATED NEUROMEDIN-B RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003080.1|UniProtKB=W5M5I4 W5M5I4 PTHR13269:SF6 NUCLEOPORIN NDC1 NUCLEOPORIN NDC1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005094.1|UniProtKB=W5MCM8 W5MCM8 SUGP1 PTHR23340:SF0 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013346.1|UniProtKB=W5N748 W5N748 PTHR13723:SF281 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005098.1|UniProtKB=W5MCN3 W5MCN3 PTHR13268:SF0 BREAST CARCINOMA AMPLIFIED SEQUENCE 3 BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to nutrient levels#GO:0031667;response to stress#GO:0006950;response to extracellular stimulus#GO:0009991;response to starvation#GO:0042594 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012128.1|UniProtKB=W5N2R5 W5N2R5 PTHR22834:SF19 NUCLEAR FUSION PROTEIN FUS2 DYNAMIN-BINDING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003196.1|UniProtKB=W5M5W8 W5M5W8 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 negative regulation of biological process#GO:0048519;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;protein folding#GO:0006457;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CCKR signaling map#P06959>HSP27#P07154;VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231;p38 MAPK pathway#P05918>HSP27#P06016 LEPOC|Ensembl=ENSLOCG00000005401.1|UniProtKB=W5MDQ1 W5MDQ1 PTHR10270:SF204 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-18 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;tube morphogenesis#GO:0035239;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;vasculature development#GO:0001944;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;vasculogenesis#GO:0001570;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;tube development#GO:0035295;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;angiogenesis#GO:0001525;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000015895.1|UniProtKB=W5NG19 W5NG19 PTHR42985:SF2 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012017.1|UniProtKB=W5N2B7 W5N2B7 PTHR15428:SF0 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 ESM-1 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 LEPOC|Ensembl=ENSLOCG00000013995.1|UniProtKB=W5N9E9 W5N9E9 PTHR24115:SF600 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF23 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008831.1|UniProtKB=W5MQU6 W5MQU6 PTHR24043:SF9 SCAVENGER RECEPTOR CLASS F MULTIPLE EGF LIKE DOMAINS 11 cargo receptor activity#GO:0038024 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012538.1|UniProtKB=W5N483 W5N483 PTHR24217:SF10 PUTATIVE-RELATED SYNAPTOPODIN 2-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;positive regulation of actin filament bundle assembly#GO:0032233;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament bundle assembly#GO:0032231;positive regulation of biological process#GO:0048518 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003700.1|UniProtKB=W5M7N9 W5M7N9 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011154.1|UniProtKB=W5MZA1 W5MZA1 PTHR12489:SF18 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 5 PROTEIN response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of sound#GO:0007605;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;response to abiotic stimulus#GO:0009628;sensory perception of mechanical stimulus#GO:0050954 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000537.1|UniProtKB=W5LWT6 W5LWT6 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003835.1|UniProtKB=W5M871 W5M871 PTHR11866:SF4 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN F2-ALPHA RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000011062.1|UniProtKB=W5MYX0 W5MYX0 PTHR24124:SF3 ANKYRIN REPEAT FAMILY A ANKYRIN REPEAT FAMILY A PROTEIN 2 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013901.1|UniProtKB=W5N930 W5N930 PTHR33332:SF51 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008458.1|UniProtKB=W5MPI7 W5MPI7 PTHR11042:SF160 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of translational initiation#GO:0006446;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009492.1|UniProtKB=W5MT85 W5MT85 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010561.1|UniProtKB=W5MX41 W5MX41 PTHR13585:SF19 CHASCON, ISOFORM D-RELATED ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000004793.1|UniProtKB=W5MBI8 W5MBI8 TNFSF15 PTHR11471:SF24 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001152.1|UniProtKB=W5LYW4 W5LYW4 PTHR13052:SF3 NFRKB-RELATED NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007868.1|UniProtKB=W5MMD7 W5MMD7 PTHR11442:SF88 HEMOGLOBIN FAMILY MEMBER GLOBIN FAMILY PROFILE DOMAIN-CONTAINING PROTEIN antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000017877.1|UniProtKB=W5NMX1 W5NMX1 PTHR10489:SF611 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 6 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000017375.1|UniProtKB=W5NLH1 W5NLH1 PTHR24233:SF10 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000488.1|UniProtKB=W5LWM7 W5LWM7 PTHR21472:SF30 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000010118.1|UniProtKB=W5MVG9 W5MVG9 PTHR45775:SF4 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN GEM carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;transporter regulator activity#GO:0141108;anion binding#GO:0043168;channel regulator activity#GO:0016247;ion binding#GO:0043167 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013495.1|UniProtKB=W5N7P2 W5N7P2 PTHR10372:SF9 PLAKOPHILLIN-RELATED CATENIN DELTA-2 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;postsynapse organization#GO:0099173;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;dendritic spine morphogenesis#GO:0060997;dendrite morphogenesis#GO:0048813;cell development#GO:0048468;neuron projection development#GO:0031175;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;adherens junction#GO:0005912;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 Cadherin signaling pathway#P00012>P120#P00473 LEPOC|Ensembl=ENSLOCG00000006652.1|UniProtKB=W5MI25 W5MI25 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE SUBUNIT O, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;oxidative phosphorylation#GO:0006119;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011145.1|UniProtKB=W5MZ91 W5MZ91 PTHR16082:SF2 AP-5 COMPLEX SUBUNIT MU-1 AP-5 COMPLEX SUBUNIT MU-1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000011732.1|UniProtKB=W5N1B1 W5N1B1 CCDC69 PTHR24200:SF6 TOUCAN, ISOFORM A COILED-COIL DOMAIN-CONTAINING PROTEIN 69 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013208.1|UniProtKB=W5N6L1 W5N6L1 PTHR10556:SF27 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE TRANS-2,3-ENOYL-COA REDUCTASE-LIKE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001584.1|UniProtKB=W5M0J9 W5M0J9 PTHR45628:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT N-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1B calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655;signaling#GO:0023052;import into cell#GO:0098657 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;GABA-B receptor II signaling#P05731>Ca channel#P05753;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 LEPOC|Ensembl=ENSLOCG00000002107.1|UniProtKB=W5M244 W5M244 PTHR10033:SF14 CALSEQUESTRIN CALSEQUESTRIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;calcium-mediated signaling#GO:0019722;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of metal ion transport#GO:0010959;regulation of sequestering of calcium ion#GO:0051282;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;cell communication#GO:0007154;cellular process#GO:0009987;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;sarcoplasmic reticulum#GO:0016529;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;intracellular organelle lumen#GO:0070013;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;endoplasmic reticulum#GO:0005783;I band#GO:0031674 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000015191.1|UniProtKB=W5NDI2 W5NDI2 PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012243.1|UniProtKB=W5N345 W5N345 PTHR24058:SF35 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of cell cycle#GO:0045787;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;regulation of cell cycle G2/M phase transition#GO:1902749;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organelle disassembly#GO:1903008;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;protein-RNA complex organization#GO:0071826 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016622.1|UniProtKB=W5NIS6 W5NIS6 PTHR14897:SF5 WD REPEAT AND COILED-COIL-CONTAINING PROTEIN WD REPEAT AND COILED-COIL-CONTAINING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 LEPOC|Ensembl=ENSLOCG00000003328.1|UniProtKB=W5M6D0 W5M6D0 PTHR11430:SF133 LIPOCALIN LIPOCALIN transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000000916.1|UniProtKB=W5LY14 W5LY14 KCNQ1 PTHR47735:SF14 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016661.1|UniProtKB=W5NIX2 W5NIX2 PTHR24058:SF22 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013462.1|UniProtKB=W5N7J2 W5N7J2 PTHR10908:SF4 SEROTONIN N-ACETYLTRANSFERASE ARYLALKYLAMINE N-ACETYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 response to stimulus#GO:0050896;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;response to abiotic stimulus#GO:0009628;rhythmic process#GO:0048511;response to radiation#GO:0009314 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000017020.1|UniProtKB=W5NK80 W5NK80 PTHR11348:SF7 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 2 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000010417.1|UniProtKB=W5MWL4 W5MWL4 PTHR36688:SF2 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009498.1|UniProtKB=W5MT93 W5MT93 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007321.1|UniProtKB=W5MKG7 W5MKG7 PTHR14791:SF25 BOMB/KIRA PROTEINS PROTEIN WWC3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;cell motility#GO:0048870;regulation of RNA biosynthetic process#GO:2001141;regulation of growth#GO:0040008;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell migration#GO:0016477;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014885.1|UniProtKB=W5NCH2 W5NCH2 PTHR24072:SF394 RHO FAMILY GTPASE RAS HOMOLOG FAMILY MEMBER UB GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013540.1|UniProtKB=W5N7U2 W5N7U2 PTHR14795:SF0 HELICASE RELATED TRANSMEMBRANE PROTEIN 62 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000001078.1|UniProtKB=W5LYK9 W5LYK9 DNAH1 PTHR22878:SF73 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED DYNEIN AXONEMAL HEAVY CHAIN 1 LEPOC|Ensembl=ENSLOCG00000015491.1|UniProtKB=W5NEK9 W5NEK9 PTHR13520:SF0 RAD50-INTERACTING PROTEIN 1 RINT-1 RAD50-INTERACTING PROTEIN 1 localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;biological regulation#GO:0065007;regulation of localization#GO:0032879;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015609.1|UniProtKB=W5NF06 W5NF06 PTHR44390:SF1 CENTROSOMAL PROTEIN OF 41 KDA CENTROSOMAL PROTEIN OF 41 KDA organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006266.1|UniProtKB=W5MGR7 W5MGR7 PTHR13167:SF39 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010396.1|UniProtKB=W5MWI9 W5MWI9 PTHR45897:SF2 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 transport#GO:0006810;trans-synaptic signaling#GO:0099537;nitrogen compound transport#GO:0071705;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;nitrogen compound metabolic process#GO:0006807;organic cation transport#GO:0015695;biological regulation#GO:0065007;synaptic signaling#GO:0099536;neuromuscular synaptic transmission#GO:0007274;cell-cell signaling#GO:0007267;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;neuron projection#GO:0043005;cell body#GO:0044297;perikaryon#GO:0043204;cell projection#GO:0042995;plasma membrane#GO:0005886 transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072 LEPOC|Ensembl=ENSLOCG00000010497.1|UniProtKB=W5MWV9 W5MWV9 C3orf38 PTHR21084:SF1 DENSE INCISORS DENSE INCISORS LEPOC|Ensembl=ENSLOCG00000011485.1|UniProtKB=W5N0I0 W5N0I0 PTHR11905:SF114 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 11 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007439.1|UniProtKB=W5MKW7 W5MKW7 PTHR45897:SF5 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;organic cation transport#GO:0015695;transport#GO:0006810;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009603.1|UniProtKB=W5MTM7 W5MTM7 PTHR23302:SF17 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of sound#GO:0007605;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;response to abiotic stimulus#GO:0009628;sensory perception of mechanical stimulus#GO:0050954 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002261.1|UniProtKB=W5M2N9 W5M2N9 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006036.1|UniProtKB=W5MFY7 W5MFY7 PTHR10199:SF92 THROMBOSPONDIN THROMBOSPONDIN-4 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015906.1|UniProtKB=W5NG26 W5NG26 PTHR10816:SF18 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014809.1|UniProtKB=W5NC73 W5NC73 PTHR11829:SF201 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010660.1|UniProtKB=W5MXE4 W5MXE4 PTHR15907:SF4 DUF614 FAMILY PROTEIN-RELATED PLACENTA-ASSOCIATED 8, TANDEM DUPLICATE 1-RELATED positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000001780.1|UniProtKB=W5M108 W5M108 PTHR14392:SF2 NIBAN FAMILY MEMBER PROTEIN NIBAN 2 LEPOC|Ensembl=ENSLOCG00000002416.1|UniProtKB=W5M377 W5M377 PTHR24073:SF528 DRAB5-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 22 HOMOLOG GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001938.1|UniProtKB=W5M1J4 W5M1J4 PTHR42921:SF1 ACETOACETYL-COA SYNTHETASE ACETOACETYL-COA SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000007238.1|UniProtKB=W5MK52 W5MK52 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000005285.1|UniProtKB=W5MDC9 W5MDC9 PTHR24229:SF11 NEUROPEPTIDES RECEPTOR NOCICEPTIN RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000015079.1|UniProtKB=W5ND51 W5ND51 PTHR12420:SF15 PHD FINGER PROTEIN PHD FINGER PROTEIN 6 enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007647.1|UniProtKB=W5MLL6 W5MLL6 PTHR10352:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 3 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000012989.1|UniProtKB=W5N5T9 W5N5T9 PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000012700.1|UniProtKB=W5N4R9 W5N4R9 PTHR24410:SF16 HL07962P-RELATED GALECTIN-3-BINDING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009378.1|UniProtKB=W5MSU1 W5MSU1 IL1RAP PTHR11890:SF20 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN regulation of DNA-binding transcription factor activity#GO:0051090;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of NF-kappaB transcription factor activity#GO:0051092;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003666.1|UniProtKB=W5M7J6 W5M7J6 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003800.1|UniProtKB=W5M825 W5M825 PTHR24078:SF288 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 4 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;chaperone-mediated protein folding#GO:0061077;chaperone cofactor-dependent protein refolding#GO:0051085;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein folding#GO:0006457;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;'de novo' protein folding#GO:0006458;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018109.1|UniProtKB=W5NNK1 W5NNK1 PTHR10494:SF4 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;ossification#GO:0001503;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;osteoblast differentiation#GO:0001649;dorsal/ventral pattern formation#GO:0009953;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011744.1|UniProtKB=W5N1C8 W5N1C8 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007409.1|UniProtKB=W5MKU3 W5MKU3 INPP5A PTHR12997:SF10 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE hydrolase activity#GO:0016787;inositol phosphate phosphatase activity#GO:0052745;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000018252.1|UniProtKB=W5NNZ4 W5NNZ4 PTHR47266:SF28 ENDONUCLEASE-RELATED TRANSPOSON TF2-1 POLYPROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000001058.1|UniProtKB=W5LYI5 W5LYI5 PTHR23349:SF40 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000001015.1|UniProtKB=W5LYF3 W5LYF3 PTHR11465:SF9 CATALASE CATALASE antioxidant activity#GO:0016209;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009637.1|UniProtKB=W5MTS2 W5MTS2 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000005364.1|UniProtKB=W5MDM6 W5MDM6 PTHR16296:SF2 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007517.1|UniProtKB=W5ML63 W5ML63 PTCHD3 PTHR10796:SF60 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013691.1|UniProtKB=W5N8C1 W5N8C1 KCNAB3 PTHR43150:SF3 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-3 binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;channel regulator activity#GO:0016247;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of monoatomic ion transport#GO:0043269 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010177.1|UniProtKB=W5MVQ0 W5MVQ0 PTHR11360:SF92 MONOCARBOXYLATE TRANSPORTER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017813.1|UniProtKB=W5NMQ8 W5NMQ8 PTHR15035:SF9 CORTICOLIBERIN/UROCORTIN CORTICOLIBERIN peptide hormone#PC00179 Cortocotropin releasing factor receptor signaling pathway#P04380>CRF#P04454;Cortocotropin releasing factor receptor signaling pathway#P04380>ProCRF (Pro Corticotropin-Releasing Factor)#P04456 LEPOC|Ensembl=ENSLOCG00000015858.1|UniProtKB=W5NFW5 W5NFW5 PTHR11769:SF20 HYALURONIDASE HYALURONIDASE PH-20 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;macromolecule catabolic process#GO:0009057;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008300.1|UniProtKB=W5MNX2 W5MNX2 PTHR15237:SF1 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9A DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;response to radiation#GO:0009314;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;cellular response to stress#GO:0033554;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000015642.1|UniProtKB=W5NF47 W5NF47 PTHR15526:SF5 MUSKELIN MUSKELIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009782.1|UniProtKB=W5MU94 W5MU94 PTHR24418:SF87 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL2 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000005902.1|UniProtKB=W5MFH0 W5MFH0 PTHR10947:SF3 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009916.1|UniProtKB=W5MUR1 W5MUR1 PTHR24403:SF100 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014277.1|UniProtKB=W5NAC8 W5NAC8 PTHR12358:SF95 SPHINGOSINE KINASE CERAMIDE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000014180.1|UniProtKB=W5NA06 W5NA06 PTHR16655:SF5 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT 2-RELATED LEPOC|Ensembl=ENSLOCG00000017313.1|UniProtKB=W5NLA9 W5NLA9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010521.1|UniProtKB=W5MWY4 W5MWY4 PTHR46735:SF7 CALPAIN, SMALL SUBUNIT 1 A-RELATED SORCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000007762.1|UniProtKB=W5MM15 W5MM15 PTHR34756:SF1 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000007980.1|UniProtKB=W5MMT8 W5MMT8 PTHR10621:SF29 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A proteasome binding#GO:0070628;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011575.1|UniProtKB=W5N0S0 W5N0S0 PTHR14555:SF6 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED RAB EFFECTOR MYRIP cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;actin binding#GO:0003779;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004841.1|UniProtKB=W5MBQ9 W5MBQ9 PTHR24261:SF16 PLASMINOGEN-RELATED PHOSPHOINOSITIDE-3-KINASE-INTERACTING PROTEIN 1 binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010068.1|UniProtKB=W5MVA3 W5MVA3 PTHR13809:SF5 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-5-RELATED protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 LEPOC|Ensembl=ENSLOCG00000017593.1|UniProtKB=W5NM39 W5NM39 PLEKHF1 PTHR46280:SF2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 cellular localization#GO:0051641;vacuolar transport#GO:0007034;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001263.1|UniProtKB=W5LZ75 W5LZ75 PTHR10201:SF317 MATRIX METALLOPROTEINASE MATRILYSIN-LIKE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011303.1|UniProtKB=W5MZT4 W5MZT4 PPP3CA PTHR45673:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED PROTEIN PHOSPHATASE 3 CATALYTIC SUBUNIT ALPHA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;calcineurin-mediated signaling#GO:0097720;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CCKR signaling map#P06959>CaN#P07178;T cell activation#P00053>Calcineurin#P01315;Wnt signaling pathway#P00057>Calcineurin#P01446;B cell activation#P00010>Calcineurin#P00386;Gonadotropin-releasing hormone receptor pathway#P06664>Caln#P06728 LEPOC|Ensembl=ENSLOCG00000014166.1|UniProtKB=W5N9Z9 W5N9Z9 PTHR24416:SF46 TYROSINE-PROTEIN KINASE RECEPTOR MAST_STEM CELL GROWTH FACTOR RECEPTOR KIT signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;hematopoietic progenitor cell differentiation#GO:0002244;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;mononuclear cell differentiation#GO:1903131;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;hemopoiesis#GO:0030097;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;positive regulation of cell migration#GO:0030335;positive regulation of protein kinase activity#GO:0045860;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015495.1|UniProtKB=W5NEL0 W5NEL0 PTHR11309:SF11 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006517.1|UniProtKB=W5MHN6 W5MHN6 PTHR11043:SF2 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-1 cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000008933.1|UniProtKB=W5MR70 W5MR70 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000003813.1|UniProtKB=W5M841 W5M841 PTHR13105:SF22 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008002.1|UniProtKB=W5MMW7 W5MMW7 PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009297.1|UniProtKB=W5MSI2 W5MSI2 PTHR21669:SF2 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS CAPZ-INTERACTING PROTEIN cytoskeletal protein binding#GO:0008092;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;actin binding#GO:0003779 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;system process#GO:0003008;vesicle-mediated transport#GO:0016192;nervous system process#GO:0050877;cellular process#GO:0009987;striated muscle contraction#GO:0006941;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;skeletal muscle contraction#GO:0003009;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;muscle system process#GO:0003012;muscle contraction#GO:0006936 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009349.1|UniProtKB=W5MSQ0 W5MSQ0 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008712.1|UniProtKB=W5MQE3 W5MQE3 PTHR11636:SF125 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010587.1|UniProtKB=W5MX79 W5MX79 PTHR45652:SF2 GLIAL FIBRILLARY ACIDIC PROTEIN DESMIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 skeletal muscle organ development#GO:0060538;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;muscle organ development#GO:0007517;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;animal organ development#GO:0048513;developmental process#GO:0032502;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;Z disc#GO:0030018;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016;plasma membrane#GO:0005886;I band#GO:0031674 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000005382.1|UniProtKB=W5MDN0 W5MDN0 PTHR47025:SF2 AUTOIMMUNE REGULATOR AUTOIMMUNE REGULATOR LEPOC|Ensembl=ENSLOCG00000000634.1|UniProtKB=W5LX43 W5LX43 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017108.1|UniProtKB=W5NKI4 W5NKI4 PTHR45632:SF3 LD33804P KELCH-LIKE PROTEIN 32 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006114.1|UniProtKB=W5MG84 W5MG84 PTHR21481:SF0 PROTEIN CLEC16A PROTEIN CLEC16A endosomal transport#GO:0016197;cellular localization#GO:0051641;regulation of catabolic process#GO:0009894;vacuolar transport#GO:0007034;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;regulation of protein-containing complex disassembly#GO:0043244;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of autophagosome maturation#GO:1901096;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005079.1|UniProtKB=W5MCK9 W5MCK9 PTHR13096:SF7 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 2 histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008510.1|UniProtKB=W5MPP7 W5MPP7 PTHR11645:SF0 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;oxidoreductase#PC00176 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 LEPOC|Ensembl=ENSLOCG00000000191.1|UniProtKB=W5LVQ6 W5LVQ6 PTHR24377:SF929 IP01015P-RELATED ZINC FINGER PROTEIN 665 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007598.1|UniProtKB=W5MLG2 W5MLG2 PTHR11267:SF91 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000013510.1|UniProtKB=W5N7Q1 W5N7Q1 PTHR31931:SF2 PROTEIN CHURCHILL PROTEIN CHURCHILL fibroblast growth factor receptor signaling pathway#GO:0008543;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to fibroblast growth factor#GO:0071774;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to fibroblast growth factor stimulus#GO:0044344;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 LEPOC|Ensembl=ENSLOCG00000004832.1|UniProtKB=W5MBP5 W5MBP5 PTHR43157:SF30 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 11-LIKE glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001470.1|UniProtKB=W5LZX5 W5LZX5 PTHR11848:SF78 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 15 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000007386.1|UniProtKB=W5MKR0 W5MKR0 PTHR45623:SF8 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 6 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005081.1|UniProtKB=W5MCL2 W5MCL2 PTHR12191:SF14 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP10 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015068.1|UniProtKB=W5ND34 W5ND34 PTHR23412:SF14 STEREOCILIN RELATED STEREOCILIN-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 stereocilium#GO:0032420;cell surface#GO:0009986;stereocilium bundle#GO:0032421;non-motile cilium#GO:0097730;kinocilium#GO:0060091;cluster of actin-based cell projections#GO:0098862;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001929.1|UniProtKB=W5M1I4 W5M1I4 PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Angiogenesis#P00005>RasGAP#P00190;Interleukin signaling pathway#P00036>RasGAP#P00975;EGF receptor signaling pathway#P00018>GAP#P00546;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;Angiogenesis#P00005>GAP#P00205;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 LEPOC|Ensembl=ENSLOCG00000013797.1|UniProtKB=W5N8R0 W5N8R0 PTHR23271:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005276.1|UniProtKB=W5MDA0 W5MDA0 PTHR22883:SF466 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC4 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006165.1|UniProtKB=W5MGD4 W5MGD4 PTHR19855:SF11 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 LEPOC|Ensembl=ENSLOCG00000001314.1|UniProtKB=W5LZE1 W5LZE1 PTHR10786:SF0 CHOLECYSTOKININ CHOLECYSTOKININ neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 multicellular organismal process#GO:0032501;digestion#GO:0007586 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;extracellular region#GO:0005576;axon#GO:0030424 CCKR signaling map#P06959>Pro CCK @ TGN#P07174;CCKR signaling map#P06959>CCK-83#P07118;CCKR signaling map#P06959>CCK-58#P07164;CCKR signaling map#P06959>CCK-GRR#P07131;CCKR signaling map#P06959>Pre-pro CCK @ ER#P07128;CCKR signaling map#P06959>CCK-8#P07226;CCKR signaling map#P06959>CCK-33#P07045;CCKR signaling map#P06959>CCK#P07077;CCKR signaling map#P06959>CCK-22#P07022;CCKR signaling map#P06959>Signal-pre-pro CCK#P07223;CCKR signaling map#P06959>CCK-G#P07062;CCKR signaling map#P06959>Pro-CCK @ secretory granule#P07206 LEPOC|Ensembl=ENSLOCG00000002440.1|UniProtKB=W5M3B0 W5M3B0 PTHR24330:SF7 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003962.1|UniProtKB=W5M8M7 W5M8M7 PTHR45703:SF4 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 17 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003000.1|UniProtKB=W5M591 W5M591 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013161.1|UniProtKB=W5N6F4 W5N6F4 PTHR25465:SF5 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011637.1|UniProtKB=W5N0Z1 W5N0Z1 PTHR10466:SF1 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;hexose metabolic process#GO:0019318;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 LEPOC|Ensembl=ENSLOCG00000006764.1|UniProtKB=W5MIG5 W5MIG5 PTHR13271:SF151 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE SET DOMAIN-CONTAINING PROTEIN 4 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017401.1|UniProtKB=W5NLJ7 W5NLJ7 PTHR26451:SF928 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 148-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012110.1|UniProtKB=W5N2P1 W5N2P1 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4-LIKE ISOFORM X1 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000015636.1|UniProtKB=W5NF41 W5NF41 PTHR23055:SF165 CALCIUM BINDING PROTEINS CALSENILIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;double-stranded DNA binding#GO:0003690;transporter regulator activity#GO:0141108;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cation binding#GO:0043169;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;potassium channel regulator activity#GO:0015459;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;calcium ion binding#GO:0005509;ion binding#GO:0043167;channel regulator activity#GO:0016247;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;regulation of metal ion transport#GO:0010959;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of RNA biosynthetic process#GO:2001141;regulation of potassium ion transport#GO:0043266;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;regulation of biosynthetic process#GO:0009889;regulation of monoatomic ion transport#GO:0043269;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000012354.1|UniProtKB=W5N3K1 W5N3K1 IL11RA PTHR23036:SF192 CYTOKINE RECEPTOR INTERLEUKIN 11 RECEPTOR ALPHA CHAIN signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular response to organic substance#GO:0071310;positive regulation of cell population proliferation#GO:0008284;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009676.1|UniProtKB=W5MTW2 W5MTW2 PTHR47266:SF28 ENDONUCLEASE-RELATED TRANSPOSON TF2-1 POLYPROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000008710.1|UniProtKB=W5MQF1 W5MQF1 PTHR10943:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000015560.1|UniProtKB=W5NEU4 W5NEU4 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 69 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010758.1|UniProtKB=W5MXS5 W5MXS5 PTHR23179:SF28 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE-ACTIVATING PROTEIN 20 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016323.1|UniProtKB=W5NHP5 W5NHP5 PTHR47980:SF23 LD44762P RAB10, MEMBER RAS ONCOGENE FAMILY cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 LEPOC|Ensembl=ENSLOCG00000003921.1|UniProtKB=W5M8H8 W5M8H8 PTHR19918:SF3 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001325.1|UniProtKB=W5LZH7 W5LZH7 PTHR24083:SF100 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;intracellular receptor signaling pathway#GO:0030522;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002754.1|UniProtKB=W5M4D0 W5M4D0 PTHR33768:SF7 MIP11318P CFAP97 DOMAIN CONTAINING 2 LEPOC|Ensembl=ENSLOCG00000002961.1|UniProtKB=W5M525 W5M525 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008537.1|UniProtKB=W5MPS6 W5MPS6 PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB mitotic cytokinesis#GO:0000281;cell division#GO:0051301;mitotic cell cycle#GO:0000278;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cytokinesis#GO:0000910 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014684.1|UniProtKB=W5NBR9 W5NBR9 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188 LEPOC|Ensembl=ENSLOCG00000015666.1|UniProtKB=W5NF76 W5NF76 PTHR24356:SF181 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C THETA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>PKCtheta#P07140;EGF receptor signaling pathway#P00018>PKC#P00565;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;T cell activation#P00053>PKC-theta#P01318;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Gonadotropin-releasing hormone receptor pathway#P06664>PKCe/theta#P06798;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 LEPOC|Ensembl=ENSLOCG00000002104.1|UniProtKB=W5M241 W5M241 PTHR22939:SF127 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000614.1|UniProtKB=W5LX23 W5LX23 PTHR45627:SF6 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 2 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Nicotine pharmacodynamics pathway#P06587>ADCY2#P06606;Opioid proopiomelanocortin pathway#P05917>AC#P06011;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;Enkephalin release#P05913>AC#P05978;Opioid prodynorphin pathway#P05916>AC#P06001;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;Opioid proenkephalin pathway#P05915>AC#P05993 LEPOC|Ensembl=ENSLOCG00000005488.1|UniProtKB=W5ME16 W5ME16 PTHR11991:SF0 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000004191.1|UniProtKB=W5M9G0 W5M9G0 PTHR21508:SF4 MITOGUARDIN MITOGUARDIN 2 mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;organelle fusion#GO:0048284 LEPOC|Ensembl=ENSLOCG00000013681.1|UniProtKB=W5N8B3 W5N8B3 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010686.1|UniProtKB=W5MXI2 W5MXI2 PTHR12736:SF11 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007444.1|UniProtKB=W5MKW9 W5MKW9 PTHR23349:SF5 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR SCLERAXIS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002692.1|UniProtKB=W5M4I9 W5M4I9 PTPRM PTHR19134:SF206 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012434.1|UniProtKB=W5N3U6 W5N3U6 PTHR10361:SF40 SODIUM-BILE ACID COTRANSPORTER HEPATIC SODIUM_BILE ACID COTRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010858.1|UniProtKB=W5MY53 W5MY53 PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 LEPOC|Ensembl=ENSLOCG00000004680.1|UniProtKB=W5MB52 W5MB52 PTHR48083:SF20 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001256.1|UniProtKB=W5LZ79 W5LZ79 PTHR11937:SF487 ACTIN ACTIN-LIKE PROTEIN 6A protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular protein-containing complex#GO:0140535;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015027.1|UniProtKB=W5NCZ1 W5NCZ1 PTHR13778:SF2 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013263.1|UniProtKB=W5N6T0 W5N6T0 PTHR15907:SF186 DUF614 FAMILY PROTEIN-RELATED CORNIFELIN HOMOLOG B-LIKE LEPOC|Ensembl=ENSLOCG00000008904.1|UniProtKB=W5MR32 W5MR32 PTHR11309:SF46 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 LEPOC|Ensembl=ENSLOCG00000005315.1|UniProtKB=W5MDK5 W5MDK5 PTHR24023:SF987 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000009700.1|UniProtKB=W5MTZ8 W5MTZ8 PTHR22968:SF9 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>PKC#P01425;CCKR signaling map#P06959>PRKD1#P07103;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 LEPOC|Ensembl=ENSLOCG00000006707.1|UniProtKB=W5MI92 W5MI92 PTHR10658:SF78 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC 1 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002589.1|UniProtKB=W5M3T3 W5M3T3 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L LEPOC|Ensembl=ENSLOCG00000016901.1|UniProtKB=W5NJT2 W5NJT2 PTHR10926:SF17 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50A organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003653.1|UniProtKB=W5M7I4 W5M7I4 PTHR12751:SF4 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular developmental process#GO:0048869;stem cell development#GO:0048864;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;ameboidal-type cell migration#GO:0001667;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;neural crest cell differentiation#GO:0014033;mesenchyme development#GO:0060485;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000017840.1|UniProtKB=W5NMT4 W5NMT4 PTHR11309:SF31 FRIZZLED FRIZZLED-7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000004456.1|UniProtKB=W5MAC1 W5MAC1 PTHR23003:SF6 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016204.1|UniProtKB=W5NH72 W5NH72 PTHR14430:SF2 RABIN3-RELATED RAB-3A-INTERACTING PROTEIN localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cellular anatomical entity#GO:0110165;organelle#GO:0043226;secretory vesicle#GO:0099503;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016935.1|UniProtKB=W5NJX5 W5NJX5 PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147;RNA metabolism protein#PC00031;mRNA capping factor#PC00145 LEPOC|Ensembl=ENSLOCG00000011337.1|UniProtKB=W5MZY2 W5MZY2 PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG vesicle fusion#GO:0006906;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;response to extracellular stimulus#GO:0009991;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;cellular response to starvation#GO:0009267;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;cellular response to extracellular stimulus#GO:0031668;organelle fusion#GO:0048284;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;establishment of protein localization to vacuole#GO:0072666;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;protein transport#GO:0015031;cellular response to external stimulus#GO:0071496;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009789.1|UniProtKB=W5MUA9 W5MUA9 PTHR10760:SF3 TORSIN TORSIN-3A envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013365.1|UniProtKB=W5N764 W5N764 PTHR12373:SF0 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007865.1|UniProtKB=W5MMF8 W5MMF8 PTHR18902:SF24 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED NUCLEAR MITOTIC APPARATUS PROTEIN 1 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002153.1|UniProtKB=W5M299 W5M299 PTHR11431:SF23 FERRITIN FERRITIN cation binding#GO:0043169;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;intracellular iron ion homeostasis#GO:0006879;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000017031.1|UniProtKB=W5NK89 W5NK89 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010072.1|UniProtKB=W5MVB0 W5MVB0 PTHR46169:SF17 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002837.1|UniProtKB=W5M4M8 W5M4M8 PTHR13006:SF7 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 704 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008013.1|UniProtKB=W5MMX0 W5MMX0 PTHR15273:SF8 DAN DOMAIN FAMILY MEMBER 5 CERBERUS Wnt signaling pathway#P00057>Cerebus#P01445 LEPOC|Ensembl=ENSLOCG00000003902.1|UniProtKB=W5M8G0 W5M8G0 PTHR11640:SF136 NEPHRIN NEPHRIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004134.1|UniProtKB=W5M983 W5M983 PTHR21017:SF14 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013765.1|UniProtKB=W5N8L5 W5N8L5 PTHR23412:SF6 STEREOCILIN RELATED MESOTHELIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000018197.1|UniProtKB=W5NNT9 W5NNT9 FAM181B PTHR33766:SF2 PROTEIN FAM181B PROTEIN FAM181B LEPOC|Ensembl=ENSLOCG00000005319.1|UniProtKB=W5MDF2 W5MDF2 PTHR31108:SF7 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014219.1|UniProtKB=W5NA52 W5NA52 PTHR10589:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE BAP1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013655.1|UniProtKB=W5N877 W5N877 PTHR10285:SF171 URIDINE KINASE URACIL PHOSPHORIBOSYLTRANSFERASE HOMOLOG transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151 LEPOC|Ensembl=ENSLOCG00000013407.1|UniProtKB=W5N7C0 W5N7C0 PTHR13199:SF13 GH03947P ATOS HOMOLOG PROTEIN A LEPOC|Ensembl=ENSLOCG00000012246.1|UniProtKB=W5N357 W5N357 PTHR15225:SF1 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN INTERFERON-INDUCED 35 KDA PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000007045.1|UniProtKB=W5MJH6 W5MJH6 PTHR10648:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT WW-BINDING DOMAIN-CONTAINING PROTEIN-RELATED phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000004323.1|UniProtKB=W5M9V3 W5M9V3 PTHR43290:SF2 MEVALONATE KINASE MEVALONATE KINASE carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 LEPOC|Ensembl=ENSLOCG00000006478.1|UniProtKB=W5MHG3 W5MHG3 PTHR24394:SF16 ZINC FINGER PROTEIN HYPERMETHYLATED IN CANCER 1 PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013631.1|UniProtKB=W5N845 W5N845 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal peptide processing#GO:0006465 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 protease#PC00190;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Signal Peptidase#P04589 LEPOC|Ensembl=ENSLOCG00000001914.1|UniProtKB=W5M1H1 W5M1H1 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017145.1|UniProtKB=W5NKN9 W5NKN9 PTHR25465:SF80 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005493.1|UniProtKB=W5ME39 W5ME39 PTHR12552:SF3 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 42 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000017189.1|UniProtKB=W5NKT5 W5NKT5 PTHR11537:SF39 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000010508.1|UniProtKB=W5MWX4 W5MWX4 PTHR48092:SF5 KNIRPS-RELATED PROTEIN-RELATED GLUCOCORTICOID RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>GR#P06810 LEPOC|Ensembl=ENSLOCG00000006568.1|UniProtKB=W5MHS8 W5MHS8 PTHR15502:SF7 CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED CALCINEURIN-BINDING PROTEIN CABIN-1 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;phosphatase inhibitor#PC00183 LEPOC|Ensembl=ENSLOCG00000010365.1|UniProtKB=W5MWE0 W5MWE0 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000007546.1|UniProtKB=W5ML96 W5ML96 PTHR11576:SF3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 SI:CH211-14A17.6-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000008685.1|UniProtKB=W5MQA4 W5MQA4 PTHR19277:SF1 PENTRAXIN NEURONAL PENTRAXIN-2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004195.1|UniProtKB=W5M9F9 W5M9F9 PTHR24264:SF15 TRYPSIN-RELATED RIKEN CDNA 2210010C04 GENE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013467.1|UniProtKB=W5N7K7 W5N7K7 PTHR18896:SF121 PHOSPHOLIPASE D PHOSPHOLIPASE D2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;phospholipid catabolic process#GO:0009395;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular membrane-bounded organelle#GO:0043231;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 phospholipase#PC00186 Ras Pathway#P04393>PLD#P04574;Angiogenesis#P00005>PLD#P00204;Parkinson disease#P00049>PLD2#P01207 LEPOC|Ensembl=ENSLOCG00000004814.1|UniProtKB=W5MBM3 W5MBM3 PTHR23102:SF24 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014404.1|UniProtKB=W5NAS6 W5NAS6 PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007632.1|UniProtKB=W5MLJ7 W5MLJ7 MGMT PTHR46460:SF1 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000015158.1|UniProtKB=W5NDE8 W5NDE8 PTHR46489:SF3 STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;intracellular sterol transport#GO:0032366;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;intracellular cholesterol transport#GO:0032367;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of lipid metabolic process#GO:0019216;intracellular transport#GO:0046907;lipid localization#GO:0010876;regulation of lipid biosynthetic process#GO:0046890;regulation of metabolic process#GO:0019222;intracellular lipid transport#GO:0032365 LEPOC|Ensembl=ENSLOCG00000002815.1|UniProtKB=W5M4K2 W5M4K2 GNAZ PTHR10218:SF65 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z) SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Dopamine receptor mediated signaling pathway#P05912>GNAZ#P05964 LEPOC|Ensembl=ENSLOCG00000013356.1|UniProtKB=W5N751 W5N751 CXCL8 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A PLATELET BASIC PROTEIN cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016752.1|UniProtKB=W5NJ95 W5NJ95 PTHR22603:SF101 CHOLINE/ETHANOALAMINE KINASE CHOLINE KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phosphatidylcholine biosynthetic process#GO:0006656;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000016160.1|UniProtKB=W5NH07 W5NH07 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005723.1|UniProtKB=W5MEV9 W5MEV9 PTHR46877:SF17 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000007324.1|UniProtKB=W5MKG8 W5MKG8 BMERB1 PTHR22704:SF1 BMERB DOMAIN-CONTAINING PROTEIN 1-RELATED BMERB DOMAIN-CONTAINING PROTEIN 1 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of protein-containing complex disassembly#GO:0043244;regulation of cellular component organization#GO:0051128;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein depolymerization#GO:1901879;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein-containing complex disassembly#GO:0043242;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010196.1|UniProtKB=W5MVS6 W5MVS6 PLPP1 PTHR10165:SF26 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015909.1|UniProtKB=W5NG38 W5NG38 PTHR11042:SF194 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED DOUBLE-STRANDED RNA ACTIVATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of translational initiation#GO:0006446;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008359.1|UniProtKB=W5MP53 W5MP53 PTHR15711:SF1 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 1-LIKE nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009525.1|UniProtKB=W5MTC7 W5MTC7 PTHR13803:SF43 SEC24-RELATED PROTEIN CIRCULARLY PERMUTATED RAS PROTEIN 1-LIKE cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000006806.1|UniProtKB=W5MIN0 W5MIN0 PTHR45807:SF5 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;cytokine receptor binding#GO:0005126 signal transduction#GO:0007165;response to cytokine#GO:0034097;macromolecule modification#GO:0043412;response to peptide hormone#GO:0043434;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;peptidyl-tyrosine phosphorylation#GO:0018108;response to peptide#GO:1901652;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;receptor signaling pathway via JAK-STAT#GO:0007259;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;peptidyl-tyrosine modification#GO:0018212;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor tyrosine protein kinase#PC00168 Interferon-gamma signaling pathway#P00035>Jak1#P00953;Angiogenesis#P00005>JAK1#P00185;PDGF signaling pathway#P00047>Jak#P01155;JAK/STAT signaling pathway#P00038>Jak#P01034 LEPOC|Ensembl=ENSLOCG00000006586.1|UniProtKB=W5MHU4 W5MHU4 PTHR38653:SF1 GENE 572-RELATED GENE 572-RELATED LEPOC|Ensembl=ENSLOCG00000007730.1|UniProtKB=W5MLX4 W5MLX4 PTHR23248:SF38 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 1 phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004671.1|UniProtKB=W5MB38 W5MB38 PTHR13341:SF6 MIR-INTERACTING SAPOSIN-LIKE PROTEIN PROTEIN CANOPY HOMOLOG 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000164.1|UniProtKB=W5LVM4 W5LVM4 PTHR24230:SF31 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011899.1|UniProtKB=W5N1X4 W5N1X4 PTHR10639:SF28 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN B protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;postsynapse#GO:0098794;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Huntington disease#P00029>Clathrin#P00798 LEPOC|Ensembl=ENSLOCG00000003037.1|UniProtKB=W5M5D0 W5M5D0 PTHR11959:SF11 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008865.1|UniProtKB=W5MQZ1 W5MQZ1 PTHR47979:SF6 DRAB11-RELATED RAB11A, MEMBER RAS ONCOGENE FAMILY, LIKE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;protein-containing complex localization#GO:0031503 synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;postsynapse#GO:0098794 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000006972.1|UniProtKB=W5MJ78 W5MJ78 PTHR24411:SF3 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;response to oxidative stress#GO:0006979;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;cellular response to oxidative stress#GO:0034599;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000002673.1|UniProtKB=W5M441 W5M441 PTHR22603:SF102 CHOLINE/ETHANOALAMINE KINASE CHOLINE KINASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phosphatidylcholine biosynthetic process#GO:0006656;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000665.1|UniProtKB=W5LX78 W5LX78 PTHR21014:SF2 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 1 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011400.1|UniProtKB=W5N058 W5N058 PTHR24072:SF21 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHON GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 LEPOC|Ensembl=ENSLOCG00000012871.1|UniProtKB=W5N5D3 W5N5D3 PTHR31516:SF17 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000347.1|UniProtKB=W5LW73 W5LW73 PTHR14905:SF18 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING 10, TANDEM DUPLICATE 1-RELATED LEPOC|Ensembl=ENSLOCG00000012903.1|UniProtKB=W5N5H8 W5N5H8 LSM5 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013415.1|UniProtKB=W5N7D2 W5N7D2 PTHR14057:SF9 TRANSCRIPTION FACTOR ONECUT HEPATOCYTE NUCLEAR FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010969.1|UniProtKB=W5MYM0 W5MYM0 PTHR19981:SF7 TALIN TALIN-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell adhesion#GO:0007155;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 Integrin signalling pathway#P00034>Talin#P00943 LEPOC|Ensembl=ENSLOCG00000009301.1|UniProtKB=W5MSI9 W5MSI9 PTHR11003:SF350 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015350.1|UniProtKB=W5NE30 W5NE30 PTHR22603:SF91 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000015313.1|UniProtKB=W5NDY3 W5NDY3 PTHR12268:SF16 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-RELATED PROTEIN 2 biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005572.1|UniProtKB=W5MEB6 W5MEB6 PTHR46760:SF1 TRANSCRIPTION TERMINATION FACTOR 1 TRANSCRIPTION TERMINATION FACTOR 1 General transcription by RNA polymerase I#P00022>TTF-I#P00654;General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 LEPOC|Ensembl=ENSLOCG00000001064.1|UniProtKB=W5LYJ1 W5LYJ1 PTHR46187:SF3 ALKALINE CERAMIDASE 3 ALKALINE CERAMIDASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013876.1|UniProtKB=W5N901 W5N901 PTHR16275:SF8 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010014.1|UniProtKB=W5MV60 W5MV60 PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010247.1|UniProtKB=W5MVY8 W5MVY8 PTHR23504:SF32 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HIPPOCAMPUS ABUNDANT TRANSCRIPT-LIKE PROTEIN 1 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001749.1|UniProtKB=W5M0V9 W5M0V9 PTHR16161:SF0 TRANSCRIPTIONAL PROTEIN SWT1 TRANSCRIPTIONAL PROTEIN SWT1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016958.1|UniProtKB=W5NK07 W5NK07 PTHR11783:SF107 SULFOTRANSFERASE SULT SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016361.1|UniProtKB=W5NHU4 W5NHU4 PTHR10257:SF6 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT ALPHA ISOFORM phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000015225.1|UniProtKB=W5NDM7 W5NDM7 PTHR10747:SF33 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000016706.1|UniProtKB=W5NJ29 W5NJ29 PTHR23077:SF171 AAA-FAMILY ATPASE NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014208.1|UniProtKB=W5NA43 W5NA43 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000016040.1|UniProtKB=W5NGJ9 W5NGJ9 PTHR15583:SF10 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E-LIKE-RELATED signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012242.1|UniProtKB=W5N354 W5N354 CFI PTHR24253:SF91 TRANSMEMBRANE PROTEASE SERINE COMPLEMENT FACTOR I serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001539.1|UniProtKB=W5M074 W5M074 PTHR22599:SF32 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2A ISOFORM X1-RELATED protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000009483.1|UniProtKB=W5MT72 W5MT72 PTHR23504:SF77 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HIPPOCAMPUS ABUNDANT TRANSCRIPT 1 PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000071.1|UniProtKB=W5LVC5 W5LVC5 PTHR11528:SF87 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein stabilization#GO:0050821;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 somatodendritic compartment#GO:0036477;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell body#GO:0044297;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000000136.1|UniProtKB=W5LVJ0 W5LVJ0 PTHR31019:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 14 SMALL INTEGRAL MEMBRANE PROTEIN 14 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014575.1|UniProtKB=W5NBC9 W5NBC9 PTHR14083:SF1 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1B localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000009265.1|UniProtKB=W5MSE1 W5MSE1 PTHR24103:SF609 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM13 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to external biotic stimulus#GO:0043207;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;innate immune response#GO:0045087;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;defense response#GO:0006952;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;ERAD pathway#GO:0036503;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;defense response to symbiont#GO:0140546;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of macroautophagy#GO:0016239;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;macromolecule modification#GO:0043412;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;positive regulation of response to stimulus#GO:0048584;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011113.1|UniProtKB=W5MZ43 W5MZ43 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;protein-DNA complex#GO:0032993;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear replication fork#GO:0043596;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 Cell cycle#P00013>Pre-replication Complex#P00478 LEPOC|Ensembl=ENSLOCG00000003817.1|UniProtKB=W5M847 W5M847 KCNB2 PTHR11537:SF134 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016434.1|UniProtKB=W5NI39 W5NI39 PTHR24166:SF30 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 63 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006386.1|UniProtKB=W5MH54 W5MH54 PTHR14319:SF7 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 POST-GPI ATTACHMENT TO PROTEINS FACTOR 6 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007553.1|UniProtKB=W5MLA6 W5MLA6 PTHR10046:SF24 ATP DEPENDENT LON PROTEASE FAMILY MEMBER LON PROTEASE HOMOLOG 2, PEROXISOMAL serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011601.1|UniProtKB=W5N0U6 W5N0U6 PTHR45956:SF1 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN PROTEIN RUFY3 regulation of biological process#GO:0050789;regulation of axonogenesis#GO:0050770;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cellular component organization#GO:0051128;regulation of neuron projection development#GO:0010975 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012302.1|UniProtKB=W5N3C8 W5N3C8 PTHR13475:SF4 NEUGRIN NEUGRIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018224.1|UniProtKB=W5NNW6 W5NNW6 PTHR23226:SF377 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011692.1|UniProtKB=W5N158 W5N158 PTHR11616:SF102 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER SLC6A17 leucine transport#GO:0015820;neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000012696.1|UniProtKB=W5N4R3 W5N4R3 PTHR16435:SF5 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS ASSOCIATED 6-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000003269.1|UniProtKB=W5M652 W5M652 PTHR12308:SF36 ANOCTAMIN ANOCTAMIN inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014756.1|UniProtKB=W5NC14 W5NC14 PTHR46735:SF3 CALPAIN, SMALL SUBUNIT 1 A-RELATED CALPAIN SMALL SUBUNIT 1-RELATED Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000002133.1|UniProtKB=W5M279 W5M279 PTHR48041:SF90 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 1 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;sterol transporter activity#GO:0015248;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;transmembrane transport#GO:0055085;sterol transport#GO:0015918;transport#GO:0006810;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid transport#GO:0006869;cholesterol homeostasis#GO:0042632;localization#GO:0051179;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;lipid localization#GO:0010876;cholesterol efflux#GO:0033344 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000334.1|UniProtKB=W5LW54 W5LW54 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016404.1|UniProtKB=W5NHZ9 W5NHZ9 PTHR11036:SF36 SEMAPHORIN SEMAPHORIN-3D molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012499.1|UniProtKB=W5N426 W5N426 PTHR13341:SF4 MIR-INTERACTING SAPOSIN-LIKE PROTEIN CANOPY FGF SIGNALING REGULATOR 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018254.1|UniProtKB=W5NNZ6 W5NNZ6 ADRA2A PTHR24248:SF24 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2A ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000007854.1|UniProtKB=W5MMC4 W5MMC4 PTHR31463:SF4 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;defense response#GO:0006952 LEPOC|Ensembl=ENSLOCG00000007737.1|UniProtKB=W5MLY4 W5MLY4 PTHR10502:SF175 ANNEXIN ANNEXIN A13 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000004952.1|UniProtKB=W5MC42 W5MC42 PTHR24396:SF25 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 644 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002709.1|UniProtKB=W5M469 W5M469 PTHR10699:SF15 NEUROMODULIN NEUROMODULIN carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;protein binding#GO:0005515;lipid binding#GO:0008289;calmodulin binding#GO:0005516;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;developmental growth#GO:0048589;regeneration#GO:0031099;multicellular organism development#GO:0007275;tissue regeneration#GO:0042246;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;response to wounding#GO:0009611;cell morphogenesis involved in neuron differentiation#GO:0048667;response to stress#GO:0006950;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016432.1|UniProtKB=W5NI40 W5NI40 PTHR11417:SF33 SOMATOTROPIN,PROLACTIN PROLACTIN LIKE molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000013059.1|UniProtKB=W5N624 W5N624 PTHR15046:SF2 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN BETA-1,4 N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;amino sugar metabolic process#GO:0006040;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000010332.1|UniProtKB=W5MW99 W5MW99 PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014573.1|UniProtKB=W5NBC5 W5NBC5 PTHR12419:SF4 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 5 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006882.1|UniProtKB=W5MIW7 W5MIW7 PTHR19304:SF10 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000002759.1|UniProtKB=W5M4D9 W5M4D9 PTHR31584:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000009538.1|UniProtKB=W5MTF0 W5MTF0 PTHR24409:SF308 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN CONTAINING 11 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010337.1|UniProtKB=W5MWA6 W5MWA6 PTHR12027:SF93 WNT RELATED PROTEIN WNT-2B molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000011830.1|UniProtKB=W5N1N8 W5N1N8 PTHR45874:SF1 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-A10 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012204.1|UniProtKB=W5N308 W5N308 PTHR22834:SF9 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 37 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013842.1|UniProtKB=W5N8W5 W5N8W5 PTHR46708:SF11 TENASCIN RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA-LIKE extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017383.1|UniProtKB=W5NLH9 W5NLH9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004507.1|UniProtKB=W5MAI2 W5MAI2 GGT7 PTHR11686:SF54 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 7 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;peptide catabolic process#GO:0043171;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009421.1|UniProtKB=W5MSY8 W5MSY8 PTHR35353:SF1 OSTEOCRIN OSTEOCRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000008978.1|UniProtKB=W5MRC7 W5MRC7 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012544.1|UniProtKB=W5N489 W5N489 PTHR33775:SF1 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED PROLINE-RICH BASIC PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005526.1|UniProtKB=W5ME68 W5ME68 PTHR11977:SF29 VILLIN GELSOLIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;cellular component biogenesis#GO:0044085;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;central nervous system development#GO:0007417;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;cell projection assembly#GO:0030031;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000004757.1|UniProtKB=W5MBE7 W5MBE7 PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;ion binding#GO:0043167;isomerase activity#GO:0016853 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 LEPOC|Ensembl=ENSLOCG00000016277.1|UniProtKB=W5NHG9 W5NHG9 PTHR24161:SF18 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC17 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005148.1|UniProtKB=W5MCU3 W5MCU3 PTHR11447:SF8 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN 63 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 p53 pathway feedback loops 2#P04398>p53#P04668;p53 pathway by glucose deprivation#P04397>p53#P04640;P53 pathway feedback loops 1#P04392>p73DeltaN#P04537;p53 pathway#P00059>p53#P01485;P53 pathway feedback loops 1#P04392>p53#P04539;Huntington disease#P00029>p53#P00797;P53 pathway feedback loops 1#P04392>p73DeltaN#G04685;p53 pathway#P00059>p53#G04702 LEPOC|Ensembl=ENSLOCG00000016833.1|UniProtKB=W5NJJ5 W5NJJ5 PTHR18860:SF3 14-3-3 PROTEIN 14-3-3 PROTEIN THETA localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 LEPOC|Ensembl=ENSLOCG00000008283.1|UniProtKB=W5MNV9 W5MNV9 PTHR23337:SF3 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 MORC FAMILY CW-TYPE ZINC FINGER 2 LEPOC|Ensembl=ENSLOCG00000016882.1|UniProtKB=W5NJQ9 W5NJQ9 PTHR34988:SF1 PROTEIN, PUTATIVE-RELATED DNA-BINDING PROTEIN LEPOC|Ensembl=ENSLOCG00000003976.1|UniProtKB=W5M8P6 W5M8P6 GARNL3 PTHR15711:SF62 RAP GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 LEPOC|Ensembl=ENSLOCG00000006760.1|UniProtKB=W5MIJ8 W5MIJ8 CABCOCO1 PTHR28457:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012164.1|UniProtKB=W5N2V5 W5N2V5 PTHR46426:SF1 PROTEIN DISULFIDE-ISOMERASE TMX3 PROTEIN DISULFIDE-ISOMERASE TMX3 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002345.1|UniProtKB=W5M2Z0 W5M2Z0 PTHR24248:SF143 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(4) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;regulation of metal ion transport#GO:0010959;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;negative regulation of lyase activity#GO:0051350;negative regulation of cell communication#GO:0010648;regulation of monoatomic ion transmembrane transport#GO:0034765;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;response to nitrogen compound#GO:1901698;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;negative regulation of monoatomic ion transport#GO:0043271;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;negative regulation of cyclase activity#GO:0031280;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of adenylate cyclase activity#GO:0007194;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965 LEPOC|Ensembl=ENSLOCG00000008960.1|UniProtKB=W5MRA6 W5MRA6 PTHR24179:SF30 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 16A phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000009745.1|UniProtKB=W5MU46 W5MU46 PTHR28682:SF2 INHIBITORY SYNAPTIC FACTOR 2A-RELATED PROTEIN INSYN2B LEPOC|Ensembl=ENSLOCG00000008409.1|UniProtKB=W5MPB4 W5MPB4 PTHR45638:SF6 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3 monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;ligand-gated monoatomic cation channel activity#GO:0099094;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000001500.1|UniProtKB=W5M015 W5M015 PTHR23159:SF14 CENTROSOMAL PROTEIN 2 TESTIS-SPECIFIC GENE 10 PROTEIN cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;centriole assembly#GO:0098534;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014079.1|UniProtKB=W5N9P0 W5N9P0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002592.1|UniProtKB=W5M3V8 W5M3V8 PTHR13367:SF3 UBIQUITIN THIOESTERASE TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;protein modification by small protein removal#GO:0070646;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;cell migration#GO:0016477 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>A20#P01348 LEPOC|Ensembl=ENSLOCG00000015790.1|UniProtKB=W5NFN1 W5NFN1 PTHR22973:SF11 LD35087P GOLGI RESIDENT PROTEIN GCP60 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007739.1|UniProtKB=W5MLY5 W5MLY5 PTHR14815:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 17 DDB1- AND CUL4-ASSOCIATED FACTOR 17 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000011365.1|UniProtKB=W5N015 W5N015 PTHR10627:SF59 SCP160 BICAUDAL C HOMOLOG 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010928.1|UniProtKB=W5MYE2 W5MYE2 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG LEPOC|Ensembl=ENSLOCG00000001884.1|UniProtKB=W5M1D1 W5M1D1 PTHR11785:SF73 AMINO ACID TRANSPORTER ASC-TYPE AMINO ACID TRANSPORTER 1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;alanine transport#GO:0032328;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;organic acid transmembrane transport#GO:1903825 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007955.1|UniProtKB=W5MMQ6 W5MMQ6 ACAD10 PTHR48083:SF35 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 10 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000010922.1|UniProtKB=W5MYD4 W5MYD4 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004539.1|UniProtKB=W5MAM2 W5MAM2 PTHR13396:SF4 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;transport#GO:0006810;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;monoatomic cation transport#GO:0006812;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;metal ion transport#GO:0030001;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;monoatomic ion transport#GO:0006811;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012661.1|UniProtKB=W5N4M4 W5N4M4 PTHR12821:SF0 BYSTIN BYSTIN snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000003079.1|UniProtKB=W5M5I9 W5M5I9 PTHR11254:SF396 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of monoatomic ion transport#GO:0043269;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of monoatomic ion transmembrane transport#GO:0034765;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;negative regulation of biosynthetic process#GO:0009890;protein modification by small protein conjugation or removal#GO:0070647;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;protein K63-linked ubiquitination#GO:0070534;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000003027.1|UniProtKB=W5M5F5 W5M5F5 PTHR12877:SF16 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10-LIKE PROTEIN signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;positive regulation of actin filament bundle assembly#GO:0032233;actin filament-based process#GO:0030029;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;signaling#GO:0023052;SREBP signaling pathway#GO:0032933;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036;cellular response to stress#GO:0033554;regulation of actin filament bundle assembly#GO:0032231 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000005980.1|UniProtKB=W5MFR9 W5MFR9 PTHR31007:SF1 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 protein kinase regulator activity#GO:0019887;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase binding#GO:0019900 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000001300.1|UniProtKB=W5LZD3 W5LZD3 PTHR34479:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 LEPOC|Ensembl=ENSLOCG00000006244.1|UniProtKB=W5MGN1 W5MGN1 PTHR48024:SF10 GEO13361P1-RELATED RNA-BINDING PROTEIN 24 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;mRNA stabilization#GO:0048255;positive regulation of cell differentiation#GO:0045597;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of mRNA splicing, via spliceosome#GO:0048024;negative regulation of RNA catabolic process#GO:1902369;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002922.1|UniProtKB=W5M4X5 W5M4X5 PTHR15902:SF2 NEURITIN-RELATED NEURITIN-LIKE PROTEIN cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;neurogenesis#GO:0022008;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;growth#GO:0040007;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;cell growth#GO:0016049;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004207.1|UniProtKB=W5M9H0 W5M9H0 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014186.1|UniProtKB=W5NA15 W5NA15 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-6 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000009634.1|UniProtKB=W5MTR5 W5MTR5 PTHR44899:SF4 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002885.1|UniProtKB=W5M4W4 W5M4W4 PTHR18968:SF166 THIAMINE PYROPHOSPHATE ENZYMES 2-HYDROXYACYL-COA LYASE 2 nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997;Valine biosynthesis#P02785>Acetolactate synthase#P03216 LEPOC|Ensembl=ENSLOCG00000005610.1|UniProtKB=W5MEG1 W5MEG1 PTHR44324:SF6 WD40 REPEAT DOMAIN 95 EF-HAND CALCIUM BINDING DOMAIN 8 LEPOC|Ensembl=ENSLOCG00000000074.1|UniProtKB=W5LVD0 W5LVD0 THOP1 PTHR11804:SF84 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED SACCHAROLYSIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002365.1|UniProtKB=W5M318 W5M318 PTHR31021:SF2 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1 protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000018305.1|UniProtKB=W5NP47 W5NP47 PTHR13936:SF2 PROFILIN PROFILIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of anatomical structure size#GO:0090066;positive regulation of organelle organization#GO:0010638;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;positive regulation of actin filament bundle assembly#GO:0032233;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of actin filament bundle assembly#GO:0032231 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 LEPOC|Ensembl=ENSLOCG00000011906.1|UniProtKB=W5N1Y4 W5N1Y4 PTHR19282:SF511 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015371.1|UniProtKB=W5NE60 W5NE60 SLC4A5 PTHR11453:SF20 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 4 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007395.1|UniProtKB=W5MKR6 W5MKR6 PTHR24340:SF21 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003278.1|UniProtKB=W5M660 W5M660 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000001589.1|UniProtKB=W5M0B7 W5M0B7 PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 TCA cycle#P00051>Succinate Dehydrogenase#P01273 LEPOC|Ensembl=ENSLOCG00000009285.1|UniProtKB=W5MSH0 W5MSH0 PTHR12000:SF21 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN-RELATED cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004623.1|UniProtKB=W5MAY3 W5MAY3 PTHR10856:SF10 CORONIN CORONIN-1C cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular developmental process#GO:0048869;stem cell development#GO:0048864;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;neural crest cell differentiation#GO:0014033;organelle organization#GO:0006996;mesenchyme development#GO:0060485;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament organization#GO:0007015;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000015695.1|UniProtKB=W5NFB1 W5NFB1 PTHR22957:SF193 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN USP6 N-TERMINAL-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000007639.1|UniProtKB=W5MLK7 W5MLK7 PTHR47980:SF15 LD44762P RAS-RELATED PROTEIN RAB-3C GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007595.1|UniProtKB=W5MLH3 W5MLH3 PTHR24208:SF95 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011857.1|UniProtKB=W5N1S2 W5N1S2 PTHR46294:SF2 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007743.1|UniProtKB=W5MLZ1 W5MLZ1 PTHR12538:SF10 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007831.1|UniProtKB=W5MM97 W5MM97 PTHR23233:SF46 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010767.1|UniProtKB=W5MXU8 W5MXU8 PTHR45639:SF5 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4L macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000013214.1|UniProtKB=W5N6L3 W5N6L3 PTHR21472:SF20 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000012007.1|UniProtKB=W5N2A6 W5N2A6 PTHR43601:SF3 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 LEPOC|Ensembl=ENSLOCG00000012183.1|UniProtKB=W5N2W9 W5N2W9 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000012324.1|UniProtKB=W5N3F5 W5N3F5 PTHR24367:SF21 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;synapse organization#GO:0050808;system development#GO:0048731;cellular component biogenesis#GO:0044085;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;cell junction organization#GO:0034330;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012341.1|UniProtKB=W5N3I4 W5N3I4 PTHR10218:SF230 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid prodynorphin pathway#P05916>G-protein#P06002;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proenkephalin pathway#P05915>G-protein#P05994;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873 LEPOC|Ensembl=ENSLOCG00000017430.1|UniProtKB=W5NLM6 W5NLM6 PTHR12002:SF89 CLAUDIN CLAUDIN-4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000016157.1|UniProtKB=W5NH01 W5NH01 PTHR15933:SF13 PROTEIN CBG16327 F-BOX ONLY PROTEIN 30 LEPOC|Ensembl=ENSLOCG00000005268.1|UniProtKB=W5MD85 W5MD85 PTHR31200:SF1 INO80 COMPLEX SUBUNIT C INO80 COMPLEX SUBUNIT C cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 LEPOC|Ensembl=ENSLOCG00000000204.1|UniProtKB=W5LVS0 W5LVS0 PTHR23411:SF41 TAPASIN IG KAPPA-B4 CHAIN C REGION immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007754.1|UniProtKB=W5MM09 W5MM09 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000017561.1|UniProtKB=W5NM07 W5NM07 PTHR24393:SF157 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016980.1|UniProtKB=W5NK32 W5NK32 PTHR15576:SF1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011624.1|UniProtKB=W5N0X5 W5N0X5 PTHR46941:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000055.1|UniProtKB=W5LVA8 W5LVA8 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009993.1|UniProtKB=W5MV31 W5MV31 PTHR10194:SF53 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 3 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008034.1|UniProtKB=W5MMZ5 W5MMZ5 MCHR1 PTHR24229:SF91 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010382.1|UniProtKB=W5MWG4 W5MWG4 HGFAC PTHR24264:SF43 TRYPSIN-RELATED HEPATOCYTE GROWTH FACTOR ACTIVATOR hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of body fluid levels#GO:0050878;cellular metabolic process#GO:0044237;wound healing#GO:0042060;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014796.1|UniProtKB=W5NC59 W5NC59 PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 LEPOC|Ensembl=ENSLOCG00000009269.1|UniProtKB=W5MSE6 W5MSE6 PTHR23055:SF80 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 3 cation binding#GO:0043169;molecular function activator activity#GO:0140677;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;enzyme activator activity#GO:0008047;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000012563.1|UniProtKB=W5N4D4 W5N4D4 PTHR24026:SF32 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 2 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000001019.1|UniProtKB=W5LYD6 W5LYD6 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005935.1|UniProtKB=W5MFK5 W5MFK5 PTHR14057:SF34 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006063.1|UniProtKB=W5MG12 W5MG12 PTHR15678:SF6 ANTIGEN MLAA-22-RELATED BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2 LEPOC|Ensembl=ENSLOCG00000013433.1|UniProtKB=W5N7F1 W5N7F1 PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B protein kinase regulator activity#GO:0019887;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase binding#GO:0019900 negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of cell population proliferation#GO:0008285;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346;regulation of phosphorylation#GO:0042325;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574 LEPOC|Ensembl=ENSLOCG00000008372.1|UniProtKB=W5MP65 W5MP65 PTHR10585:SF37 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 2 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002053.1|UniProtKB=W5M1Y7 W5M1Y7 PTHR12675:SF7 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010027.1|UniProtKB=W5MV52 W5MV52 PTHR10279:SF11 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 2 enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;positive regulation of catabolic process#GO:0009896;biological regulation#GO:0065007;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015907.1|UniProtKB=W5NG28 W5NG28 PTHR10969:SF50 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEINS 1A_1B LIGHT CHAIN 3C enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000006574.1|UniProtKB=W5MHS5 W5MHS5 PTHR20886:SF8 VANG-LIKE PROTEIN VANG-LIKE PROTEIN 1 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;epithelium development#GO:0060429;non-canonical Wnt signaling pathway#GO:0035567;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;tissue development#GO:0009888;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008106.1|UniProtKB=W5MN87 W5MN87 PTHR46756:SF25 TRANSGELIN GAS2-LIKE PROTEIN 1 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;tubulin binding#GO:0015631;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;protein localization to cytoskeleton#GO:0044380;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012152.1|UniProtKB=W5N2T8 W5N2T8 PTHR11571:SF141 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003898.1|UniProtKB=W5M8G4 W5M8G4 PTHR48041:SF75 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 4 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;sterol transporter activity#GO:0015248;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;transmembrane transport#GO:0055085;sterol transport#GO:0015918;transport#GO:0006810;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid transport#GO:0006869;cholesterol homeostasis#GO:0042632;localization#GO:0051179;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;lipid localization#GO:0010876;cholesterol efflux#GO:0033344 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004214.1|UniProtKB=W5M9I0 W5M9I0 PTHR31247:SF17 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER DUF4203 DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008293.1|UniProtKB=W5MNW8 W5MNW8 PTHR12659:SF6 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 13 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000010578.1|UniProtKB=W5MX51 W5MX51 PTHR11685:SF371 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF14 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013396.1|UniProtKB=W5N7C1 W5N7C1 PTHR11920:SF458 GUANYLYL CYCLASE GUANYLATE CYCLASE adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000014077.1|UniProtKB=W5N9P1 W5N9P1 PTHR31054:SF6 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 ZYGOTE ARREST PROTEIN 1 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015968.1|UniProtKB=W5NGA2 W5NGA2 PTHR24410:SF27 HL07962P-RELATED BTB DOMAIN CONTAINING 3 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001705.1|UniProtKB=W5M0Q9 W5M0Q9 PTHR12939:SF4 SARCOGLYCAN GAMMA-SARCOGLYCAN blood circulation#GO:0008015;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;developmental process#GO:0032502;circulatory system process#GO:0003013;tissue development#GO:0009888;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016082.1|UniProtKB=W5NGQ6 W5NGQ6 PTHR24050:SF24 PA14 DOMAIN-CONTAINING PROTEIN EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000003148.1|UniProtKB=W5M5S6 W5M5S6 PTHR15504:SF0 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 LEPOC|Ensembl=ENSLOCG00000013123.1|UniProtKB=W5N6B6 W5N6B6 PTHR11102:SF147 SEL-1-LIKE PROTEIN SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000194.1|UniProtKB=W5LVR1 W5LVR1 PTHR12951:SF6 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG B lipid binding#GO:0008289;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;visual perception#GO:0007601;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;cytoskeleton-dependent cytokinesis#GO:0061640;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;cilium assembly#GO:0060271;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;positive regulation of macromolecule metabolic process#GO:0010604;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of endocytosis#GO:0045806;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cilium organization#GO:0044782;cell division#GO:0051301;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;developmental process#GO:0032502;transport#GO:0006810;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;organic substance transport#GO:0071702;mitotic cytokinesis#GO:0000281;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;negative regulation of cellular process#GO:0048523;cytokinesis#GO:0000910;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;multicellular organism development#GO:0007275;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;nervous system process#GO:0050877;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;positive regulation of protein metabolic process#GO:0051247;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of kinase activity#GO:0033674;sensory perception#GO:0007600;regulation of transferase activity#GO:0051338 spindle pole#GO:0000922;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;spindle#GO:0005819 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013177.1|UniProtKB=W5N6G9 W5N6G9 PTHR11691:SF62 TYPE I INTERFERON INTERFERON PHI 2-RELATED cytokine#PC00083;interferon superfamily#PC00127 LEPOC|Ensembl=ENSLOCG00000012413.1|UniProtKB=W5N3T5 W5N3T5 PTHR24169:SF21 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P100 SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;B cell activation#P00010>NFkappaB#P00370;T cell activation#P00053>NFkappaB#P01298;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 LEPOC|Ensembl=ENSLOCG00000016479.1|UniProtKB=W5NIA1 W5NIA1 PTHR19282:SF202 TETRASPANIN PERIPHERIN-2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012129.1|UniProtKB=W5N2R0 W5N2R0 PTHR24328:SF8 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000248.1|UniProtKB=W5LVW7 W5LVW7 PTHR12411:SF966 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L1-LIKE-RELATED cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011045.1|UniProtKB=W5MYW3 W5MYW3 PTHR23150:SF19 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification process#GO:0036211;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000010164.1|UniProtKB=W5MVY1 W5MVY1 DMD PTHR12268:SF25 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN muscle organ development#GO:0007517;neurogenesis#GO:0022008;muscle cell differentiation#GO:0042692;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of system process#GO:0044057;nervous system development#GO:0007399;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;synaptic signaling#GO:0099536;neuron differentiation#GO:0030182;cell-cell signaling#GO:0007267;signaling#GO:0023052;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;cell development#GO:0048468;muscle cell development#GO:0055001;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;skeletal muscle tissue development#GO:0007519 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013078.1|UniProtKB=W5N649 W5N649 PTHR42760:SF133 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006881.1|UniProtKB=W5MIW2 W5MIW2 PTHR12015:SF177 SMALL INDUCIBLE CYTOKINE A CHEMOKINE INTERLEUKIN-8-LIKE DOMAIN-CONTAINING PROTEIN cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016605.1|UniProtKB=W5NIQ0 W5NIQ0 FOXO3 PTHR45767:SF4 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O3-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CCKR signaling map#P06959>FOXO3#P07073;PI3 kinase pathway#P00048>FOXO#P01198;Interleukin signaling pathway#P00036>FKHRL1#P00994;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 LEPOC|Ensembl=ENSLOCG00000015355.1|UniProtKB=W5NE39 W5NE39 PTHR21324:SF6 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150A protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011362.1|UniProtKB=W5N013 W5N013 PTHR11610:SF165 LIPASE PANCREATIC LIPASE-RELATED PROTEIN 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008419.1|UniProtKB=W5MPC6 W5MPC6 PTHR12052:SF5 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4A nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011152.1|UniProtKB=W5MZ90 W5MZ90 PTHR10342:SF68 ARYLSULFATASE ARYLSULFATASE I LEPOC|Ensembl=ENSLOCG00000012749.1|UniProtKB=W5N4X7 W5N4X7 PTHR14365:SF1 APOPTOSIS REGULATORY PROTEIN SIVA APOPTOSIS REGULATORY PROTEIN SIVA protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000008509.1|UniProtKB=W5MPQ3 W5MPQ3 PTHR24388:SF45 ZINC FINGER PROTEIN POGO TRANSPOSABLE ELEMENT DERIVED WITH ZNF DOMAIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006990.1|UniProtKB=W5MJ98 W5MJ98 PTHR20968:SF2 ILGF DOMAIN-CONTAINING PROTEIN INSULIN-LIKE PEPTIDE INSL5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 LEPOC|Ensembl=ENSLOCG00000003227.1|UniProtKB=W5M601 W5M601 PTHR11477:SF14 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000012318.1|UniProtKB=W5N3E7 W5N3E7 PTHR48228:SF5 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE transferase#PC00220;metabolite interconversion enzyme#PC00262 Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866 LEPOC|Ensembl=ENSLOCG00000008145.1|UniProtKB=W5MND0 W5MND0 PTHR43066:SF16 RHOMBOID-RELATED PROTEIN RHOMBOID DOMAIN-CONTAINING PROTEIN 3 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008278.1|UniProtKB=W5MNV2 W5MNV2 PTHR12247:SF140 POLYCOMB GROUP PROTEIN POLYHOMEOTIC HOMOLOG 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000362.1|UniProtKB=W5LW87 W5LW87 SLC39A3 PTHR11040:SF221 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP3 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017624.1|UniProtKB=W5NM70 W5NM70 FEM1A PTHR24173:SF12 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG A macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of inflammatory response#GO:0050727;nitrogen compound metabolic process#GO:0006807;regulation of defense response#GO:0031347;proteolysis#GO:0006508;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003369.1|UniProtKB=W5M6I0 W5M6I0 PTHR42854:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005628.1|UniProtKB=W5MEI8 W5MEI8 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017759.1|UniProtKB=W5NMK4 W5NMK4 PTHR15344:SF14 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 4 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;small GTPase-mediated signal transduction#GO:0007264;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of anatomical structure size#GO:0090066;cellular response to stimulus#GO:0051716;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016113.1|UniProtKB=W5NGU6 W5NGU6 PTHR12270:SF48 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002257.1|UniProtKB=W5M2P1 W5M2P1 EME2 PTHR21077:SF6 EME1 PROTEIN CROSSOVER JUNCTION ENDONUCLEASE EME2-RELATED hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;replication fork processing#GO:0031297;intracellular signal transduction#GO:0035556;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;DNA-templated DNA replication#GO:0006261;reciprocal meiotic recombination#GO:0007131;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic DNA integrity checkpoint signaling#GO:0044774;homologous recombination#GO:0035825;DNA replication#GO:0006260;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endonuclease complex#GO:1905348 LEPOC|Ensembl=ENSLOCG00000006943.1|UniProtKB=W5MJ59 W5MJ59 PTHR10024:SF115 SYNAPTOTAGMIN SYNAPTOTAGMIN-11 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000017326.1|UniProtKB=W5NLC2 W5NLC2 PTHR37557:SF4 115 KDA PROTEIN IN TYPE-1 RETROTRANSPOSABLE ELEMENT R1DM-LIKE PROTEIN-RELATED-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006350.1|UniProtKB=W5MH08 W5MH08 PTHR24416:SF341 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TIE-1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of vasculature development#GO:1901342;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012053.1|UniProtKB=W5N2H0 W5N2H0 PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 blood circulation#GO:0008015;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;system process#GO:0003008;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;regulation of systemic arterial blood pressure#GO:0003073;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;circulatory system process#GO:0003013;protein processing#GO:0016485;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of blood pressure#GO:0008217;proteolysis#GO:0006508;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007834.1|UniProtKB=W5MMB3 W5MMB3 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000012636.1|UniProtKB=W5N4K4 W5N4K4 PTHR11036:SF17 SEMAPHORIN SEMAPHORIN-4G molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007118.1|UniProtKB=W5MJQ8 W5MJQ8 PTHR45874:SF5 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-D10 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006620.1|UniProtKB=W5MHY4 W5MHY4 PTHR13523:SF4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 10, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016311.1|UniProtKB=W5NHM4 W5NHM4 PTHR13802:SF52 MUCIN 4-RELATED MUCIN-4 LEPOC|Ensembl=ENSLOCG00000003900.1|UniProtKB=W5M8E6 W5M8E6 MBP PTHR11429:SF0 MYELIN BASIC PROTEIN MYELIN BASIC PROTEIN myelin protein#PC00161;structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003699.1|UniProtKB=W5M7S3 W5M7S3 PTHR24054:SF34 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA' transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of chromosome segregation#GO:0051983;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of chromosome separation#GO:1905818;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 LEPOC|Ensembl=ENSLOCG00000016026.1|UniProtKB=W5NGI2 W5NGI2 PTHR11850:SF126 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;central nervous system development#GO:0007417;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;tube development#GO:0035295;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;embryo development#GO:0009790;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;hemopoiesis#GO:0030097;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003270.1|UniProtKB=W5M663 W5M663 PTHR11958:SF67 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 LEPOC|Ensembl=ENSLOCG00000011631.1|UniProtKB=W5N0Y8 W5N0Y8 PTHR23504:SF31 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009948.1|UniProtKB=W5MUV7 W5MUV7 PTHR46487:SF1 DNA REPAIR PROTEIN XRCC3 DNA REPAIR PROTEIN XRCC3 nucleic acid binding#GO:0003676;four-way junction DNA binding#GO:0000400;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;telomere organization#GO:0032200;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004644.1|UniProtKB=W5MB07 W5MB07 PTHR24257:SF31 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER ELASTASE 3 LIKE ISOFORM X1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010991.1|UniProtKB=W5MYM5 W5MYM5 PTHR28670:SF1 UV-STIMULATED SCAFFOLD PROTEIN A UV-STIMULATED SCAFFOLD PROTEIN A basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to UV#GO:0009411;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006303.1|UniProtKB=W5MGV9 W5MGV9 PTHR18884:SF67 SEPTIN SEPTIN-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 LEPOC|Ensembl=ENSLOCG00000013236.1|UniProtKB=W5N6Q3 W5N6Q3 ADGRL3 PTHR23192:SF75 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000018092.1|UniProtKB=W5NNI4 W5NNI4 PTHR16100:SF5 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER TRANSMEMBRANE PROTEIN 100 cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;response to BMP#GO:0071772;response to endogenous stimulus#GO:0009719;cellular response to endogenous stimulus#GO:0071495;cellular response to growth factor stimulus#GO:0071363;response to growth factor#GO:0070848 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011051.1|UniProtKB=W5MYV8 W5MYV8 SRA1 PTHR18834:SF2 STEROID RECEPTOR RNA ACTIVATOR 1 STEROID RECEPTOR RNA ACTIVATOR 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015538.1|UniProtKB=W5NET0 W5NET0 PTHR24093:SF284 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 3 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017617.1|UniProtKB=W5NM63 W5NM63 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013480.1|UniProtKB=W5N7L7 W5N7L7 PRTG PTHR44170:SF47 PROTEIN SIDEKICK PROTOGENIN cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006218.1|UniProtKB=W5MGJ8 W5MGJ8 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of natural killer cell mediated immunity#GO:0002715;cell recognition#GO:0008037;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;regulation of immune response#GO:0050776;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;regulation of response to stress#GO:0080134;detection of stimulus#GO:0051606;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;regulation of cell killing#GO:0031341;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012446.1|UniProtKB=W5N3W2 W5N3W2 PTHR13866:SF31 SPARC OSTEONECTIN SPARC-LIKE 2 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000009718.1|UniProtKB=W5MU23 W5MU23 PTHR11977:SF30 VILLIN VILLIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000013733.1|UniProtKB=W5N8H8 W5N8H8 C17orf75 PTHR14416:SF2 PROTEIN NJMU-R1 PROTEIN NJMU-R1 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004494.1|UniProtKB=W5MAG0 W5MAG0 PTHR46942:SF1 SIALIC ACID-BINDING IG-LIKE LECTIN 15 SIALIC ACID-BINDING IG-LIKE LECTIN 15 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of hemopoiesis#GO:1903706;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of bone resorption#GO:0045124;regulation of tissue remodeling#GO:0034103;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of immune system process#GO:0002682;regulation of actin filament-based process#GO:0032970;regulation of bone remodeling#GO:0046850 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009408.1|UniProtKB=W5MSX3 W5MSX3 PTHR24134:SF9 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 ANKYRIN REPEAT AND SOCS BOX PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000004638.1|UniProtKB=W5MB22 W5MB22 PTHR14516:SF3 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000016371.1|UniProtKB=W5NHV4 W5NHV4 PTHR10390:SF61 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007712.1|UniProtKB=W5MLV5 W5MLV5 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004799.1|UniProtKB=W5MBL3 W5MBL3 PTHR13167:SF40 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015132.1|UniProtKB=W5NDB4 W5NDB4 PTHR32226:SF2 TELO2-INTERACTING PROTEIN 2 TELO2-INTERACTING PROTEIN 2 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013629.1|UniProtKB=W5N852 W5N852 PTHR15683:SF5 SCAFFOLD ATTACHMENT FACTOR B-RELATED SAFB-LIKE TRANSCRIPTION MODULATOR sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005101.1|UniProtKB=W5MCN2 W5MCN2 PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;TOR signaling#GO:0031929;regulation of phosphoprotein phosphatase activity#GO:0043666;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009048.1|UniProtKB=W5MRL5 W5MRL5 PTHR48030:SF3 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004275.1|UniProtKB=W5M9S3 W5M9S3 KDM4A PTHR10694:SF119 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4A histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000006627.1|UniProtKB=W5MHZ4 W5MHZ4 PTHR23048:SF7 MYOSIN LIGHT CHAIN 1, 3 SIMILAR TO MYOSIN, LIGHT POLYPEPTIDE 6, ALKALI, SMOOTH MUSCLE AND NON-MUSCLE structural constituent of muscle#GO:0008307;structural molecule activity#GO:0005198 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016186.1|UniProtKB=W5NH41 W5NH41 PTHR12183:SF37 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 PROTEIN MDM4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 p53 pathway#P00059>Mdm2#P01483;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway feedback loops 2#P04398>Mdm2#P04663;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;P53 pathway feedback loops 1#P04392>Mdm2#P04536;p53 pathway feedback loops 2#P04398>MDM-2#G04709;p53 pathway#P00059>MDM-2#G01563;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674 LEPOC|Ensembl=ENSLOCG00000012869.1|UniProtKB=W5N5D5 W5N5D5 PTHR45677:SF14 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 1-LIKE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 LEPOC|Ensembl=ENSLOCG00000003875.1|UniProtKB=W5M8B5 W5M8B5 PTHR46715:SF1 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727 lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;pigmentation#GO:0043473;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;vacuole organization#GO:0007033;neutrophil chemotaxis#GO:0030593;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;myeloid leukocyte migration#GO:0097529;vesicle organization#GO:0016050;leukocyte chemotaxis#GO:0030595;chemotaxis#GO:0006935;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;phagocytosis#GO:0006909;endocytosis#GO:0006897;neutrophil migration#GO:1990266;vesicle-mediated transport#GO:0016192;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;membrane fusion#GO:0061025;response to chemical#GO:0042221;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;regulation of cellular process#GO:0050794;melanosome organization#GO:0032438;biological regulation#GO:0065007;lytic vacuole organization#GO:0080171;cell migration#GO:0016477;import into cell#GO:0098657;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000342.1|UniProtKB=W5LW67 W5LW67 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016966.1|UniProtKB=W5NK13 W5NK13 PTHR24245:SF1 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 63-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012849.1|UniProtKB=W5N5A6 W5N5A6 PTHR10605:SF53 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005327.1|UniProtKB=W5MDF7 W5MDF7 PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 LEPOC|Ensembl=ENSLOCG00000018014.1|UniProtKB=W5NNA6 W5NNA6 FUT9 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014306.1|UniProtKB=W5NAF8 W5NAF8 PTHR11850:SF378 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS3 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;central nervous system development#GO:0007417;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;tube development#GO:0035295;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;embryo development#GO:0009790;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;hemopoiesis#GO:0030097;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009571.1|UniProtKB=W5MTJ2 W5MTJ2 PTHR46029:SF1 C-TERMINAL-BINDING PROTEIN C-TERMINAL BINDING PROTEIN-LIKE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010028.1|UniProtKB=W5MV49 W5MV49 TCEANC PTHR11477:SF7 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007256.1|UniProtKB=W5MK89 W5MK89 PTHR13697:SF59 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate binding#GO:0030246;kinase activity#GO:0016301;cation binding#GO:0043169;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;monosaccharide binding#GO:0048029 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;small molecule catabolic process#GO:0044282;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;nucleoside diphosphate metabolic process#GO:0009132;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphofructokinase-1#P00672 LEPOC|Ensembl=ENSLOCG00000007331.1|UniProtKB=W5MKH1 W5MKH1 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000661.1|UniProtKB=W5LXB8 W5LXB8 PTHR12607:SF3 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;beta-catenin binding#GO:0008013 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;regulation of signal transduction#GO:0009966;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cellular component organization#GO:0051129;pattern specification process#GO:0007389;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;cell motility#GO:0048870;regulation of protein-containing complex disassembly#GO:0043244;cell fate commitment#GO:0045165;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of supramolecular fiber organization#GO:1902904;regulation of response to stimulus#GO:0048583;regulation of supramolecular fiber organization#GO:1902903;regulation of protein depolymerization#GO:1901879;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell migration#GO:0016477;negative regulation of cytoskeleton organization#GO:0051494 supramolecular complex#GO:0099080;membrane protein complex#GO:0098796;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 LEPOC|Ensembl=ENSLOCG00000013630.1|UniProtKB=W5N851 W5N851 PTHR22765:SF347 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ZNRF4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;negative regulation of biological process#GO:0048519;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;regulation of cell cycle#GO:0051726;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018216.1|UniProtKB=W5NNV8 W5NNV8 NPY5R PTHR24241:SF139 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011510.1|UniProtKB=W5N0I6 W5N0I6 PTHR10414:SF27 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINE_ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013476.1|UniProtKB=W5N7K6 W5N7K6 PTHR23194:SF3 PYGOPUS PYGOPUS HOMOLOG 1 Wnt signaling pathway#P00057>Pygo#P01464 LEPOC|Ensembl=ENSLOCG00000009258.1|UniProtKB=W5MSD2 W5MSD2 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000009371.1|UniProtKB=W5MSR9 W5MSR9 PTHR11486:SF17 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 12 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of sodium ion transport#GO:0002028;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of metal ion transport#GO:0010959;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular developmental process#GO:0048869;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000005808.1|UniProtKB=W5MF54 W5MF54 PTHR10687:SF8 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 1 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cytoplasmic vesicle membrane#GO:0030659 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009989.1|UniProtKB=W5MV06 W5MV06 WDR86 PTHR44489:SF11 FAMILY NOT NAMED WD REPEAT DOMAIN 86 LEPOC|Ensembl=ENSLOCG00000003316.1|UniProtKB=W5M6A9 W5M6A9 PTHR47034:SF1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000774.1|UniProtKB=W5LXJ6 W5LXJ6 PTHR13237:SF9 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED NEUROGUIDIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017580.1|UniProtKB=W5NM26 W5NM26 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR ODORANT RECEPTOR-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004229.1|UniProtKB=W5M9J9 W5M9J9 PTHR10201:SF166 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-19 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000013635.1|UniProtKB=W5N849 W5N849 PTHR12107:SF4 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-5 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;channel regulator activity#GO:0016247;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;system process#GO:0003008;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;receptor-mediated endocytosis#GO:0006898;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;protein localization to organelle#GO:0033365;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;positive regulation of biological process#GO:0048518;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;vacuolar transport#GO:0007034;endocytosis#GO:0006897;protein localization to vacuole#GO:0072665;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;positive regulation of synaptic transmission#GO:0050806;import into cell#GO:0098657;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 LEPOC|Ensembl=ENSLOCG00000007378.1|UniProtKB=W5MKN7 W5MKN7 PTHR46810:SF1 INACTIVE POLYGLYCYLASE TTLL10 INACTIVE POLYGLYCYLASE TTLL10 ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000005396.1|UniProtKB=W5MDP6 W5MDP6 FAM169A PTHR22442:SF3 FAMILY NOT NAMED SOLUBLE LAMIN-ASSOCIATED PROTEIN OF 75 KDA LEPOC|Ensembl=ENSLOCG00000004850.1|UniProtKB=W5MBS4 W5MBS4 PTHR16521:SF3 TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017576.1|UniProtKB=W5NM22 W5NM22 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000387.1|UniProtKB=W5LWF8 W5LWF8 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009613.1|UniProtKB=W5MTN0 W5MTN0 PTHR24115:SF352 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014418.1|UniProtKB=W5NAT8 W5NAT8 PTHR45690:SF19 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002917.1|UniProtKB=W5M4X2 W5M4X2 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017927.1|UniProtKB=W5NN21 W5NN21 PTHR24062:SF196 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004289.1|UniProtKB=W5M9T2 W5M9T2 PTHR14139:SF3 CALSYNTENIN CALSYNTENIN-2 regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of trans-synaptic signaling#GO:0099177;regulation of cell junction assembly#GO:1901888;positive regulation of synaptic transmission#GO:0050806;regulation of synapse structure or activity#GO:0050803;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016803.1|UniProtKB=W5NJG3 W5NJG3 SYNDIG1 PTHR14768:SF3 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;transport#GO:0006810;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;positive regulation of multicellular organismal process#GO:0051240;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;transport vesicle membrane#GO:0030658;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;postsynaptic specialization#GO:0099572;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001137.1|UniProtKB=W5LYS1 W5LYS1 PTHR11610:SF111 LIPASE PHOSPHOLIPASE A1 MEMBER A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 LEPOC|Ensembl=ENSLOCG00000002870.1|UniProtKB=W5M4R1 W5M4R1 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED LEPOC|Ensembl=ENSLOCG00000017067.1|UniProtKB=W5NKD1 W5NKD1 PTHR11589:SF4 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;response to growth factor#GO:0070848;regulation of signaling#GO:0023051;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;generation of neurons#GO:0048699 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;extracellular region#GO:0005576;cell junction#GO:0030054;dendrite#GO:0030425;extracellular space#GO:0005615;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000013315.1|UniProtKB=W5N717 W5N717 PTHR23220:SF89 INTEGRIN ALPHA INTEGRIN ALPHA-3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;response to stimulus#GO:0050896;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000000939.1|UniProtKB=W5LY40 W5LY40 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013527.1|UniProtKB=W5N7T3 W5N7T3 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008105.1|UniProtKB=W5MN84 W5MN84 PTHR34768:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 COILED-COIL DOMAIN CONTAINING 89 LEPOC|Ensembl=ENSLOCG00000008781.1|UniProtKB=W5MQN2 W5MQN2 OSGEPL1 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005885.1|UniProtKB=W5MFF8 W5MFF8 PTHR12276:SF50 EPSIN/ENT-RELATED EPSIN-2 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000006934.1|UniProtKB=W5MJ35 W5MJ35 PTHR24240:SF126 OPSIN NOVOPSIN-10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002206.1|UniProtKB=W5M2G6 W5M2G6 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017771.1|UniProtKB=W5NML6 W5NML6 PTHR24232:SF25 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004922.1|UniProtKB=W5MC11 W5MC11 PTHR11006:SF53 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;protein metabolic process#GO:0019538;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003890.1|UniProtKB=W5M8D3 W5M8D3 PTHR17117:SF3 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 3, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002195.1|UniProtKB=W5M2F0 W5M2F0 PTHR14899:SF0 G KINASE ANCHORING PROTEIN 1 G KINASE-ANCHORING PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018037.1|UniProtKB=W5NNC9 W5NNC9 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015357.1|UniProtKB=W5NE40 W5NE40 PTHR43326:SF1 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015380.1|UniProtKB=W5NE70 W5NE70 PTHR22599:SF30 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1A protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 CCKR signaling map#P06959>MOB1#G07283;CCKR signaling map#P06959>MOB1#G06990 LEPOC|Ensembl=ENSLOCG00000008426.1|UniProtKB=W5MPE6 W5MPE6 PTHR13140:SF865 MYOSIN MYOSIN IEB microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;transport#GO:0006810;endocytosis#GO:0006897;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000015129.1|UniProtKB=W5NDB1 W5NDB1 PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009754.1|UniProtKB=W5MU58 W5MU58 PTHR16222:SF34 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLGLYCOHYDROLASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015691.1|UniProtKB=W5NFA6 W5NFA6 MGME1 PTHR31340:SF3 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 LEPOC|Ensembl=ENSLOCG00000010243.1|UniProtKB=W5MVZ6 W5MVZ6 PTHR19972:SF14 CALBINDIN CALBINDIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;regulation of cell communication#GO:0010646;calcium ion homeostasis#GO:0055074;regulation of signaling#GO:0023051;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;regulation of synaptic plasticity#GO:0048167;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;intracellular monoatomic ion homeostasis#GO:0006873 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cytosol#GO:0005829;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000000743.1|UniProtKB=W5LXG7 W5LXG7 PTHR23226:SF377 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008841.1|UniProtKB=W5MQV0 W5MQV0 PTHR45828:SF51 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014175.1|UniProtKB=W5NA00 W5NA00 PTHR45793:SF22 HOMEOBOX PROTEIN CONE-ROD HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003063.1|UniProtKB=W5M5F7 W5M5F7 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000013708.1|UniProtKB=W5N8E1 W5N8E1 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 histone acetyltransferase complex#GO:0000123;DNA-directed RNA polymerase complex#GO:0000428;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;SAGA complex#GO:0000124;membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000015110.1|UniProtKB=W5ND89 W5ND89 PTHR24253:SF128 TRANSMEMBRANE PROTEASE SERINE OVOCHYMASE-1 PRECURSOR serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000219.1|UniProtKB=W5LVT7 W5LVT7 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016454.1|UniProtKB=W5NI70 W5NI70 PTHR10865:SF6 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;enzyme binding#GO:0019899;protein binding#GO:0005515 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007789.1|UniProtKB=W5MM47 W5MM47 PTHR45871:SF1 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A LEPOC|Ensembl=ENSLOCG00000005377.1|UniProtKB=W5MDM7 W5MDM7 PTHR13923:SF22 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31B endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000017825.1|UniProtKB=W5NMR9 W5NMR9 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000009144.1|UniProtKB=W5MRY8 W5MRY8 PTHR15718:SF6 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 3 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002427.1|UniProtKB=W5M394 W5M394 PTHR23233:SF19 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011832.1|UniProtKB=W5N1P4 W5N1P4 PTHR11960:SF75 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-1B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006250.1|UniProtKB=W5MGN5 W5MGN5 PTHR46096:SF5 PERFORIN-1 PERFORIN 1.2 PRECURSOR-RELATED wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;cell recognition#GO:0008037;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;T cell mediated immunity#GO:0002456;cell killing#GO:0001906;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;defense response to symbiont#GO:0140546;cell-cell recognition#GO:0009988;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation#GO:0001775;leukocyte mediated cytotoxicity#GO:0001909;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;adaptive immune response#GO:0002250;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;multicellular organismal process#GO:0032501;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;leukocyte activation#GO:0045321 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009687.1|UniProtKB=W5MTW9 W5MTW9 PTHR24028:SF253 CADHERIN-87A PROTOCADHERIN-7 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000010888.1|UniProtKB=W5MY90 W5MY90 PTHR13027:SF14 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG A endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000014832.1|UniProtKB=W5NCB7 W5NCB7 PTHR44998:SF1 FAMILY NOT NAMED UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT LEPOC|Ensembl=ENSLOCG00000014260.1|UniProtKB=W5NA96 W5NA96 PTHR28422:SF1 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 LEPOC|Ensembl=ENSLOCG00000009737.1|UniProtKB=W5MU43 W5MU43 PTHR10336:SF210 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-1 lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000005540.1|UniProtKB=W5ME91 W5ME91 PTHR14149:SF12 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2 nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;actin filament binding#GO:0051015;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;actin binding#GO:0003779;enzyme regulator activity#GO:0030234 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring assembly#GO:0000915;mitotic cytokinetic process#GO:1902410;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament organization#GO:0007015;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015625.1|UniProtKB=W5NF26 W5NF26 PTHR12429:SF36 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;protein localization to organelle#GO:0033365;import into cell#GO:0098657 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010627.1|UniProtKB=W5MXA4 W5MXA4 PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015082.1|UniProtKB=W5ND58 W5ND58 PTHR42884:SF3 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 1, ISOFORMS 1_1-X_2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Activin beta signaling pathway#P06210>FUR1#P06238;Endothelin signaling pathway#P00019>furin#P00575;GBB signaling pathway#P06214>FUR1#P06298;SCW signaling pathway#P06216>FUR1#P06333;DPP-SCW signaling pathway#P06212>FUR1#P06263;DPP signaling pathway#P06213>FUR1#P06290;ALP23B signaling pathway#P06209>FUR1#P06227;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;BMP/activin signaling pathway-drosophila#P06211>Furin#P06244;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;MYO signaling pathway#P06215>FUR1#P06318 LEPOC|Ensembl=ENSLOCG00000013956.1|UniProtKB=W5N993 W5N993 PTHR12276:SF112 EPSIN/ENT-RELATED EPSIN 3A-RELATED protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010592.1|UniProtKB=W5MX63 W5MX63 PTHR19282:SF155 TETRASPANIN TETRASPANIN-2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012939.1|UniProtKB=W5N5M5 W5N5M5 PTHR19282:SF184 TETRASPANIN PERIPHERIN 2 LIKE-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012983.1|UniProtKB=W5N5T0 W5N5T0 PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE dehydratase#PC00091;lyase#PC00144 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 LEPOC|Ensembl=ENSLOCG00000016905.1|UniProtKB=W5NJU3 W5NJU3 PTHR24241:SF75 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014198.1|UniProtKB=W5NA31 W5NA31 PTHR16133:SF5 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC TRANSPORTER ZIP9 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008254.1|UniProtKB=W5MNR3 W5MNR3 PTHR10366:SF241 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 2-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000006623.1|UniProtKB=W5MHZ3 W5MHZ3 PTHR22950:SF226 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 8-RELATED L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013191.1|UniProtKB=W5N6J3 W5N6J3 PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA basal RNA polymerase II transcription machinery binding#GO:0001099;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395;General transcription regulation#P00023>TFIIEbeta#P00659 LEPOC|Ensembl=ENSLOCG00000004039.1|UniProtKB=W5M8V9 W5M8V9 PTHR22957:SF682 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SI:CH211-266K8.4 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008581.1|UniProtKB=W5MPY8 W5MPY8 PTHR45739:SF4 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 2 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003518.1|UniProtKB=W5M703 W5M703 PTHR10969:SF15 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEINS 1A_1B LIGHT CHAIN 3 BETA 2-RELATED cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;microtubule binding#GO:0008017;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000001984.1|UniProtKB=W5M1P5 W5M1P5 PTHR15175:SF3 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NEUTROPHIL CYTOSOL FACTOR 2 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017499.1|UniProtKB=W5NLU5 W5NLU5 PTHR45773:SF4 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 2 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018361.1|UniProtKB=W5NPA3 W5NPA3 PTHR24247:SF193 5-HYDROXYTRYPTAMINE RECEPTOR BETA-2 ADRENERGIC RECEPTOR-LIKE cation binding#GO:0043169;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015050.1|UniProtKB=W5ND13 W5ND13 PTHR11955:SF62 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 1 fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009644.1|UniProtKB=W5MTS8 W5MTS8 PTHR23055:SF87 CALCIUM BINDING PROTEINS NEUROCALCIN-DELTA cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;actin binding#GO:0003779 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000016428.1|UniProtKB=W5NI32 W5NI32 TPO PTHR11475:SF60 OXIDASE/PEROXIDASE THYROID PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010623.1|UniProtKB=W5MXA1 W5MXA1 PTHR12137:SF2 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 10 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014916.1|UniProtKB=W5NCL0 W5NCL0 PTHR22968:SF12 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>PRKD2#P07216;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 LEPOC|Ensembl=ENSLOCG00000007231.1|UniProtKB=W5MK44 W5MK44 PTHR10404:SF36 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008968.1|UniProtKB=W5MRB6 W5MRB6 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005788.1|UniProtKB=W5MF32 W5MF32 PTHR10210:SF29 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012365.1|UniProtKB=W5N3L5 W5N3L5 PTHR16022:SF0 WD REPEAT DOMAIN 60 CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 1 LEPOC|Ensembl=ENSLOCG00000001008.1|UniProtKB=W5LYC3 W5LYC3 PTHR28682:SF6 INHIBITORY SYNAPTIC FACTOR 2A-RELATED MUCIN-5AC LEPOC|Ensembl=ENSLOCG00000012194.1|UniProtKB=W5N2Z0 W5N2Z0 PTHR24369:SF213 ANTIGEN BSP, PUTATIVE-RELATED INSULIN LIKE GROWTH FACTOR BINDING PROTEIN ACID LABILE SUBUNIT cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000607.1|UniProtKB=W5LX08 W5LX08 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010061.1|UniProtKB=W5MVA4 W5MVA4 PTHR16171:SF11 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED DNA EXCISION REPAIR PROTEIN ERCC-5 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012292.1|UniProtKB=W5N3B3 W5N3B3 PTHR12632:SF6 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 LEPOC|Ensembl=ENSLOCG00000010516.1|UniProtKB=W5MWX7 W5MWX7 PTHR43671:SF106 SERINE/THREONINE-PROTEIN KINASE NEK NIMA-LIKE KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007887.1|UniProtKB=W5MMJ1 W5MMJ1 PTHR21419:SF7 FAMILY NOT NAMED PROTEIN FAM234A LEPOC|Ensembl=ENSLOCG00000011026.1|UniProtKB=W5MYT7 W5MYT7 PTHR12247:SF79 POLYCOMB GROUP PROTEIN MBT DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012981.1|UniProtKB=W5N5T2 W5N5T2 PTHR12663:SF2 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG A DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic sister chromatid cohesion#GO:0007064;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cell cycle#GO:0007049;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009677.1|UniProtKB=W5MTW3 W5MTW3 PTHR10686:SF37 FOLATE TRANSPORTER THIAMINE TRANSPORTER 2 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009316.1|UniProtKB=W5MSK9 W5MSK9 PTHR13817:SF65 TITIN FIBRONECTIN TYPE III DOMAIN CONTAINING 3A-RELATED structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016057.1|UniProtKB=W5NGM3 W5NGM3 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000009732.1|UniProtKB=W5MU25 W5MU25 FBXO43 PTHR15493:SF1 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 43 negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of cell cycle process#GO:0010948;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016730.1|UniProtKB=W5NJ67 W5NJ67 FRMD4A PTHR46079:SF3 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4A cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;bicellular tight junction#GO:0005923;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000015518.1|UniProtKB=W5NEN9 W5NEN9 SULT6B1 PTHR11783:SF55 SULFOTRANSFERASE SULT SULFOTRANSFERASE 6B1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017363.1|UniProtKB=W5NLF9 W5NLF9 SOCS5 PTHR10155:SF15 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 5 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 LEPOC|Ensembl=ENSLOCG00000007886.1|UniProtKB=W5MMG7 W5MMG7 PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 LEPOC|Ensembl=ENSLOCG00000017371.1|UniProtKB=W5NLG7 W5NLG7 PTHR11214:SF21 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LACTOSYLCERAMIDE 1,3-N-ACETYL-BETA-D-GLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015150.1|UniProtKB=W5NDD4 W5NDD4 PTHR31281:SF2 PROTEIN FAM219A PROTEIN FAM219B LEPOC|Ensembl=ENSLOCG00000013582.1|UniProtKB=W5N7Z7 W5N7Z7 PTHR11630:SF44 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM2 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;mitotic DNA replication initiation#GO:1902975;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000017967.1|UniProtKB=W5NN61 W5NN61 PTHR13864:SF25 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED PROTEIN LYL-1-LIKE ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010277.1|UniProtKB=W5MW24 W5MW24 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013351.1|UniProtKB=W5N745 W5N745 PTHR24055:SF593 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016520.1|UniProtKB=W5NIF0 W5NIF0 PTHR11347:SF111 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000011132.1|UniProtKB=W5MZ63 W5MZ63 PTHR14191:SF7 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004537.1|UniProtKB=W5MAL8 W5MAL8 PTHR23235:SF49 KRUEPPEL-LIKE TRANSCRIPTION FACTOR WILMS TUMOR PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005888.1|UniProtKB=W5MFF3 W5MFF3 SMIM1 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008400.1|UniProtKB=W5MP99 W5MP99 PTHR15740:SF2 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN 2 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001640.1|UniProtKB=W5M0K1 W5M0K1 POR PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 LEPOC|Ensembl=ENSLOCG00000001025.1|UniProtKB=W5LYE7 W5LYE7 PTHR45653:SF6 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;syncytium formation by plasma membrane fusion#GO:0000768;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;syncytium formation#GO:0006949;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007075.1|UniProtKB=W5MJK4 W5MJK4 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013384.1|UniProtKB=W5N789 W5N789 PTHR15343:SF1 CD7 CD7 ANTIGEN-LIKE LEPOC|Ensembl=ENSLOCG00000017128.1|UniProtKB=W5NKK8 W5NKK8 PTHR19446:SF415 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE-RELATED PROTEIN WITH reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000009063.1|UniProtKB=W5MRN4 W5MRN4 PTHR10333:SF85 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 1 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011803.1|UniProtKB=W5N1K9 W5N1K9 PTHR10825:SF21 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB COMPLEX PROTEIN BMI-1 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014293.1|UniProtKB=W5NAD7 W5NAD7 PTHR21646:SF6 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005134.1|UniProtKB=W5MCS4 W5MCS4 PTHR10829:SF9 CORTACTIN AND DREBRIN ADF-H DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;positive regulation of growth#GO:0045927;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;regulation of synapse structure or activity#GO:0050803;positive regulation of multicellular organismal process#GO:0051240;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;regulation of postsynapse organization#GO:0099175;regulation of cell growth#GO:0001558;regulation of anatomical structure size#GO:0090066;postsynapse organization#GO:0099173;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;regulation of cell size#GO:0008361;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000017931.1|UniProtKB=W5NN25 W5NN25 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002535.1|UniProtKB=W5M3L5 W5M3L5 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018253.1|UniProtKB=W5NNZ5 W5NNZ5 PTHR24248:SF54 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-1 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of blood pressure#GO:0045776;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of systemic arterial blood pressure#GO:0003073;cellular process#GO:0009987;circulatory system process#GO:0003013;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of blood pressure#GO:0008217;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta1 adrenergic receptor signaling pathway#P04377>Beta1#P04433 LEPOC|Ensembl=ENSLOCG00000011578.1|UniProtKB=W5N0S7 W5N0S7 PTHR14493:SF36 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT HOMOLOG nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699 LEPOC|Ensembl=ENSLOCG00000012108.1|UniProtKB=W5N2P4 W5N2P4 DGKQ PTHR11255:SF54 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE THETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014901.1|UniProtKB=W5NCJ1 W5NCJ1 PTHR23036:SF172 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018159.1|UniProtKB=W5NNQ1 W5NNQ1 PTHR15532:SF2 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE-LIKE PROTEIN racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000004057.1|UniProtKB=W5M902 W5M902 PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000009665.1|UniProtKB=W5MTV8 W5MTV8 PTHR24020:SF18 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000003114.1|UniProtKB=W5M5L7 W5M5L7 PTHR24099:SF8 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FSD1-LIKE PROTEIN ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000763.1|UniProtKB=W5LXI9 W5LXI9 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013648.1|UniProtKB=W5N867 W5N867 PTHR10388:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002731.1|UniProtKB=W5M4A5 W5M4A5 PTHR18884:SF6 SEPTIN SEPTIN-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cell division#GO:0051301;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910;regulation of exocytosis#GO:0017157 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell division site#GO:0032153;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 LEPOC|Ensembl=ENSLOCG00000003373.1|UniProtKB=W5M6K6 W5M6K6 PTHR15622:SF1 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 2 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000015193.1|UniProtKB=W5NDI4 W5NDI4 PTHR11849:SF17 ETS TRANSCRIPTION FACTOR SPI-C transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>Ets#P00989 LEPOC|Ensembl=ENSLOCG00000013977.1|UniProtKB=W5N9B8 W5N9B8 PTHR22916:SF3 GLYCOSYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN 1 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012716.1|UniProtKB=W5N4U1 W5N4U1 PTHR13148:SF0 PER1-RELATED POST-GPI ATTACHMENT TO PROTEINS FACTOR 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008190.1|UniProtKB=W5MNI4 W5MNI4 PTHR31054:SF5 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 PROTEIN ZAR1-LIKE macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002874.1|UniProtKB=W5M4S3 W5M4S3 PTHR11568:SF4 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007112.1|UniProtKB=W5MJQ1 W5MJQ1 PTHR46283:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006176.1|UniProtKB=W5MGF3 W5MGF3 PTHR23086:SF46 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000015126.1|UniProtKB=W5NDA8 W5NDA8 DHDH PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007001.1|UniProtKB=W5MJB1 W5MJB1 PTHR45827:SF4 SORTING NEXIN SORTING NEXIN-18 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cell division#GO:0051301;cellular localization#GO:0051641;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;cell cycle process#GO:0022402;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytokinesis#GO:0000910;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003301.1|UniProtKB=W5M689 W5M689 PTHR24347:SF354 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE KINASE 33 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006326.1|UniProtKB=W5MGX5 W5MGX5 PTHR11158:SF22 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3B phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000018091.1|UniProtKB=W5NNI3 W5NNI3 PTHR24366:SF112 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS VASORIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000014964.1|UniProtKB=W5NCR3 W5NCR3 PTHR45638:SF3 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED OLFACTORY CHANNEL monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;ligand-gated monoatomic cation channel activity#GO:0099094;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008349.1|UniProtKB=W5MP28 W5MP28 PTHR46678:SF1 LECITHIN RETINOL ACYLTRANSFERASE LECITHIN RETINOL ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 retinoid metabolic process#GO:0001523;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;retinol metabolic process#GO:0042572;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;diterpenoid metabolic process#GO:0016101;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;terpenoid metabolic process#GO:0006721;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000002244.1|UniProtKB=W5M2S4 W5M2S4 PTHR23180:SF407 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000015389.1|UniProtKB=W5NE77 W5NE77 PTHR22769:SF56 MUTT/NUDIX HYDROLASE 8-OXO-DGDP PHOSPHATASE NUDT18 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017760.1|UniProtKB=W5NMK5 W5NMK5 PTHR11767:SF43 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017484.1|UniProtKB=W5NLT0 W5NLT0 PTHR15462:SF9 SERINE PROTEASE SERINE PROTEASE serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010251.1|UniProtKB=W5MVY6 W5MVY6 PTHR16768:SF7 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B-LIKE LEPOC|Ensembl=ENSLOCG00000005662.1|UniProtKB=W5MEN2 W5MEN2 PTHR24055:SF380 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NLK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>Nemo-like Kinase#P01449 LEPOC|Ensembl=ENSLOCG00000004639.1|UniProtKB=W5MB03 W5MB03 DHX35 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000002854.1|UniProtKB=W5M522 W5M522 PTHR10574:SF409 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;neuron differentiation#GO:0030182;vasculature development#GO:0001944;visual system development#GO:0150063;sensory system development#GO:0048880;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;sensory organ development#GO:0007423 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000011964.1|UniProtKB=W5N257 W5N257 PTHR24418:SF219 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TEC protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;adaptive immune response#GO:0002250;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000010263.1|UniProtKB=W5MW15 W5MW15 PTHR43658:SF14 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING], MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010880.1|UniProtKB=W5MY73 W5MY73 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003264.1|UniProtKB=W5M651 W5M651 HOOK3 PTHR18947:SF38 HOOK PROTEINS PROTEIN HOOK HOMOLOG 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005688.1|UniProtKB=W5MER1 W5MER1 PTHR23106:SF24 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 LEPOC|Ensembl=ENSLOCG00000016999.1|UniProtKB=W5NK56 W5NK56 PTHR24070:SF408 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAB-42 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015135.1|UniProtKB=W5NDC0 W5NDC0 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000007557.1|UniProtKB=W5MLA7 W5MLA7 PTHR28264:SF1 CYTOCHROME C OXIDASE SUBUNIT 7A CYTOCHROME C OXIDASE SUBUNIT 6C inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004900.1|UniProtKB=W5MBX9 W5MBX9 PTHR14097:SF7 OXIDOREDUCTASE HTATIP2 OXIDOREDUCTASE HTATIP2 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002790.1|UniProtKB=W5M4H9 W5M4H9 PTHR46596:SF1 SORTING NEXIN-4 SORTING NEXIN-4 phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of catabolic process#GO:0009894;macromolecule localization#GO:0033036;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;positive regulation of cellular catabolic process#GO:0031331;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of macroautophagy#GO:0016239;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of catabolic process#GO:0009896;positive regulation of autophagy#GO:0010508;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;early endosome#GO:0005769;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003215.1|UniProtKB=W5M5Z7 W5M5Z7 PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 LEPOC|Ensembl=ENSLOCG00000001959.1|UniProtKB=W5M1M5 W5M1M5 PTHR12369:SF46 CHONDROITIN SYNTHASE N-ACETYL-BETA-GLUCOSAMINYL-GLYCOPROTEIN 4-BETA-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000215.1|UniProtKB=W5LVT1 W5LVT1 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000001680.1|UniProtKB=W5M0M2 W5M0M2 PTHR11188:SF49 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005651.1|UniProtKB=W5MEL4 W5MEL4 PTHR12138:SF162 PRIMATE-EXPANDED PROTEIN FAMILY CHROMOSOME UNDETERMINED SCAFFOLD_275, WHOLE GENOME SHOTGUN SEQUENCE LEPOC|Ensembl=ENSLOCG00000007218.1|UniProtKB=W5MK39 W5MK39 PTHR10845:SF42 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 5 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000004103.1|UniProtKB=W5M939 W5M939 PTHR25466:SF2 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;cellular response to molecule of bacterial origin#GO:0071219;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 LEPOC|Ensembl=ENSLOCG00000016936.1|UniProtKB=W5NJX9 W5NJX9 PTHR32428:SF4 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;TORC2 signaling#GO:0038203;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000005694.1|UniProtKB=W5MER4 W5MER4 PTHR12245:SF16 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3-LIKE macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007438.1|UniProtKB=W5ML03 W5ML03 PTHR45623:SF22 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 4 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012880.1|UniProtKB=W5N5F2 W5N5F2 PTHR10957:SF3 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007884.1|UniProtKB=W5MMG4 W5MMG4 PTHR24207:SF1 ZYX102 PROTEIN FILAMIN-BINDING LIM PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 actomyosin#GO:0042641;intracellular non-membrane-bounded organelle#GO:0043232;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000009347.1|UniProtKB=W5MSP4 W5MSP4 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010656.1|UniProtKB=W5MXF5 W5MXF5 PTHR13487:SF3 SERINE PROTEASE INHIBITOR REVERSION-INDUCING CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of macromolecule metabolic process#GO:0060255;external encapsulating structure organization#GO:0045229;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013141.1|UniProtKB=W5N6C8 W5N6C8 PTHR23176:SF104 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 27 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000008821.1|UniProtKB=W5MQS1 W5MQS1 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007508.1|UniProtKB=W5ML53 W5ML53 PTHR15536:SF1 TACHYKININ-3 TACHYKININ-3 biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;regulation of blood pressure#GO:0008217;system process#GO:0003008 LEPOC|Ensembl=ENSLOCG00000013703.1|UniProtKB=W5N8F3 W5N8F3 ERN1 PTHR13954:SF17 IRE1-RELATED SERINE_THREONINE-PROTEIN KINASE_ENDORIBONUCLEASE IRE1 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;RNA endonuclease activity#GO:0004521;protein kinase activity#GO:0004672;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;RNA nuclease activity#GO:0004540 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;response to chemical#GO:0042221;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;response to topologically incorrect protein#GO:0035966;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125 LEPOC|Ensembl=ENSLOCG00000015803.1|UniProtKB=W5NFP8 W5NFP8 PTHR11908:SF80 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE_OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidoreductase#PC00176 Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809;Purine metabolism#P02769>Xanthine Oxidase#P03116 LEPOC|Ensembl=ENSLOCG00000009341.1|UniProtKB=W5MSN6 W5MSN6 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003560.1|UniProtKB=W5M764 W5M764 PTHR45920:SF3 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006726.1|UniProtKB=W5MIA9 W5MIA9 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 lipid binding#GO:0008289;structural molecule activity#GO:0005198;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004889.1|UniProtKB=W5MBW8 W5MBW8 PTHR15069:SF1 PROTEASOME ASSEMBLY CHAPERONE 1 PROTEASOME ASSEMBLY CHAPERONE 1 proteasome binding#GO:0070628;protein-containing complex binding#GO:0044877;binding#GO:0005488 protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018059.1|UniProtKB=W5NNF1 W5NNF1 PTHR24241:SF17 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1A RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;response to organic substance#GO:0010033;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012248.1|UniProtKB=W5N360 W5N360 ANKFN1 PTHR21437:SF3 WIDE AWAKE ANKYRIN REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 1 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002856.1|UniProtKB=W5M4Q0 W5M4Q0 PTHR16322:SF0 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 LEPOC|Ensembl=ENSLOCG00000003938.1|UniProtKB=W5M8L2 W5M8L2 PKD1L2 PTHR10877:SF134 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006111.1|UniProtKB=W5MG79 W5MG79 PTHR10219:SF25 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003504.1|UniProtKB=W5M728 W5M728 PTHR31691:SF1 ROTATIN ROTATIN LEPOC|Ensembl=ENSLOCG00000008660.1|UniProtKB=W5MQ89 W5MQ89 DCLK2 PTHR24347:SF376 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK2 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005001.1|UniProtKB=W5MCB3 W5MCB3 PPP1R1A PTHR15417:SF4 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;phosphatase inhibitor#PC00183 LEPOC|Ensembl=ENSLOCG00000005773.1|UniProtKB=W5MF16 W5MF16 GALNT5 PTHR11675:SF130 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016109.1|UniProtKB=W5NGU1 W5NGU1 PTHR24366:SF120 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007783.1|UniProtKB=W5MM49 W5MM49 ZSWIM6 PTHR22619:SF3 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 6 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000011672.1|UniProtKB=W5N139 W5N139 PTHR13239:SF7 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015024.1|UniProtKB=W5NCY9 W5NCY9 PTHR28657:SF4 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 2 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;biogenic amine metabolic process#GO:0006576;purine nucleotide biosynthetic process#GO:0006164;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;amino acid catabolic process#GO:0009063;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;pyridine-containing compound metabolic process#GO:0072524;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;amine metabolic process#GO:0009308;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;nucleoside phosphate biosynthetic process#GO:1901293;amino acid metabolic process#GO:0006520;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014755.1|UniProtKB=W5NC11 W5NC11 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD2 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000181.1|UniProtKB=W5LVP5 W5LVP5 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011160.1|UniProtKB=W5MZA4 W5MZA4 PTHR24083:SF48 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CCKR signaling map#P06959>TAK1#P07170 LEPOC|Ensembl=ENSLOCG00000009548.1|UniProtKB=W5MTG1 W5MTG1 PTHR10792:SF1 60S RIBOSOMAL PROTEIN L24 RIBOSOMAL PROTEIN L24 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007122.1|UniProtKB=W5MJR5 W5MJR5 PTHR44442:SF1 3-KETO-STEROID REDUCTASE 3-KETO-STEROID REDUCTASE_17-BETA-HYDROXYSTEROID DEHYDROGENASE 7 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 LEPOC|Ensembl=ENSLOCG00000016636.1|UniProtKB=W5NIU2 W5NIU2 PTHR28469:SF1 ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006281.1|UniProtKB=W5MGU7 W5MGU7 PTHR13817:SF20 TITIN MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle organ development#GO:0007517;heart development#GO:0007507;muscle cell differentiation#GO:0042692;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;heart morphogenesis#GO:0003007;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;tissue morphogenesis#GO:0048729;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006215.1|UniProtKB=W5MGK4 W5MGK4 PTHR11055:SF16 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 LEPOC|Ensembl=ENSLOCG00000005514.1|UniProtKB=W5ME49 W5ME49 PTHR12167:SF5 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE 3-LIKE PRECURSOR cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000018287.1|UniProtKB=W5NP29 W5NP29 PTHR12002:SF176 CLAUDIN CLAUDIN-4-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000012653.1|UniProtKB=W5N4L3 W5N4L3 PTHR24412:SF420 KELCH PROTEIN KELCH-LIKE PROTEIN 11 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002881.1|UniProtKB=W5M4T5 W5M4T5 PTHR11955:SF90 FATTY ACID BINDING PROTEIN FATTY ACID BINDING PROTEIN 11A fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000016501.1|UniProtKB=W5NIC7 W5NIC7 PTHR14167:SF23 SH3 DOMAIN-CONTAINING CD2-ASSOCIATED PROTEIN cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477 cytoplasm#GO:0005737;cell leading edge#GO:0031252;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013343.1|UniProtKB=W5N737 W5N737 PTHR14432:SF2 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 TANK-BINDING KINASE 1-BINDING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006508.1|UniProtKB=W5MHK7 W5MHK7 PTHR48015:SF31 SERINE/THREONINE-PROTEIN KINASE TAO TAO KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009106.1|UniProtKB=W5MRU3 W5MRU3 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;mRNA 3'-end processing#GO:0031124;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;protein-RNA complex organization#GO:0071826;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 LEPOC|Ensembl=ENSLOCG00000006621.1|UniProtKB=W5MHY7 W5MHY7 PTHR45864:SF3 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 2 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 LEPOC|Ensembl=ENSLOCG00000007095.1|UniProtKB=W5MJN2 W5MJN2 PTHR31462:SF5 ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 ENDOSOMAL_LYSOSOMAL PROTON CHANNEL TMEM175 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012056.1|UniProtKB=W5N2G6 W5N2G6 EPGN PTHR10740:SF10 TRANSFORMING GROWTH FACTOR ALPHA EPIGEN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of mitotic nuclear division#GO:0007088;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of organelle organization#GO:0010638;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of mitotic cell cycle#GO:0007346;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000014435.1|UniProtKB=W5NAY2 W5NAY2 PTHR24416:SF106 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of JNK cascade#GO:0046328;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;cell communication#GO:0007154;insulin-like growth factor receptor signaling pathway#GO:0048009;chemical homeostasis#GO:0048878;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;carbohydrate homeostasis#GO:0033500;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;plasma membrane signaling receptor complex#GO:0098802;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;axon#GO:0030424;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1R#P06703 LEPOC|Ensembl=ENSLOCG00000016002.1|UniProtKB=W5NGE7 W5NGE7 PTHR28661:SF1 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 MICROTUBULE NUCLEATION FACTOR SSNA1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014633.1|UniProtKB=W5NBL4 W5NBL4 PTHR10183:SF393 CALPAIN CALPAIN-LIKE ISOFORM X1 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001712.1|UniProtKB=W5M0T8 W5M0T8 PTHR10890:SF3 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;ligase activity#GO:0016874;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;catalytic activity, acting on a nucleic acid#GO:0140640;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017871.1|UniProtKB=W5NMW5 W5NMW5 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013729.1|UniProtKB=W5N8H2 W5N8H2 PTHR23235:SF1 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012131.1|UniProtKB=W5N2Q9 W5N2Q9 PTHR45712:SF4 AGAP008170-PA FIBROMODULIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000006301.1|UniProtKB=W5MGY0 W5MGY0 PTHR10241:SF19 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5-LIKE nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;myosin binding#GO:0017022;binding#GO:0005488;molecular function regulator activity#GO:0098772;syntaxin binding#GO:0019905;protein binding#GO:0005515;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;SNARE binding#GO:0000149 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;secretion by cell#GO:0032940 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003964.1|UniProtKB=W5M8M5 W5M8M5 PTHR14254:SF5 GENE 33 POLYPEPTIDE ERBB RECEPTOR FEEDBACK INHIBITOR 1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of epithelial cell differentiation#GO:0030856;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of ERBB signaling pathway#GO:1901184;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 LEPOC|Ensembl=ENSLOCG00000014085.1|UniProtKB=W5N9P8 W5N9P8 PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013410.1|UniProtKB=W5N7C6 W5N7C6 PTHR23268:SF102 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015953.1|UniProtKB=W5NG83 W5NG83 PTHR10556:SF37 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002724.1|UniProtKB=W5M491 W5M491 PTHR16684:SF11 CENTROMERE PROTEIN C CENTROMERE PROTEIN C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;protein-DNA complex organization#GO:0071824;kinetochore organization#GO:0051383;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;kinetochore assembly#GO:0051382;non-membrane-bounded organelle assembly#GO:0140694;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;mitotic metaphase chromosome alignment#GO:0007080;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310 centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000003226.1|UniProtKB=W5M613 W5M613 PTHR15830:SF10 TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp90 protein binding#GO:0051879 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012540.1|UniProtKB=W5N485 W5N485 PTHR31901:SF9 GH3 DOMAIN-CONTAINING PROTEIN GH3 DOMAIN-CONTAINING PROTEIN ligase activity#GO:0016874;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017136.1|UniProtKB=W5NKL9 W5NKL9 PTHR15950:SF17 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 2 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015240.1|UniProtKB=W5NDP4 W5NDP4 PTHR17098:SF2 NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015775.1|UniProtKB=W5NFK9 W5NFK9 PTHR14324:SF3 CONDENSIN-2 COMPLEX SUBUNIT H2 CONDENSIN-2 COMPLEX SUBUNIT H2 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006458.1|UniProtKB=W5MHE3 W5MHE3 PTHR11629:SF21 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000216.1|UniProtKB=W5LVT3 W5LVT3 PTHR46645:SF1 GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED GRAM DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004615.1|UniProtKB=W5MAX1 W5MAX1 PTHR11208:SF131 RNA-BINDING PROTEIN RELATED PROTEIN QUAKING-A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003072.1|UniProtKB=W5M5F1 W5M5F1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013886.1|UniProtKB=W5N923 W5N923 PTHR12429:SF14 NEURALIZED NEURALIZED-LIKE PROTEIN 4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 LEPOC|Ensembl=ENSLOCG00000001754.1|UniProtKB=W5M0X0 W5M0X0 PTHR12353:SF4 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 3 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of system process#GO:0044057 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005433.1|UniProtKB=W5MDU8 W5MDU8 PTHR10572:SF24 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE reductase#PC00198;oxidoreductase#PC00176 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA reductase#P00491 LEPOC|Ensembl=ENSLOCG00000000723.1|UniProtKB=W5LXE2 W5LXE2 PTHR28661:SF1 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 MICROTUBULE NUCLEATION FACTOR SSNA1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011696.1|UniProtKB=W5N162 W5N162 PTHR14256:SF4 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE SUBUNIT NDUFA4 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014516.1|UniProtKB=W5NB58 W5NB58 PTHR22988:SF79 MYOTONIC DYSTROPHY S/T KINASE-RELATED LOW QUALITY PROTEIN: MYOTONIN-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014595.1|UniProtKB=W5NBF1 W5NBF1 PTHR12817:SF7 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX 6B-LIKE localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000005872.1|UniProtKB=W5MFD3 W5MFD3 PTHR11842:SF10 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000009836.1|UniProtKB=W5MUG1 W5MUG1 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016868.1|UniProtKB=W5NJP8 W5NJP8 PTHR23331:SF5 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 2-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;alpha-tubulin binding#GO:0043014;binding#GO:0005488 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;actin filament-based process#GO:0030029;exocytosis#GO:0006887;Arp2/3 complex-mediated actin nucleation#GO:0034314;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010085.1|UniProtKB=W5MVD1 W5MVD1 ERMP1 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008818.1|UniProtKB=W5MQR7 W5MQR7 TTC29 PTHR46630:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 29 TETRATRICOPEPTIDE REPEAT PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000003561.1|UniProtKB=W5M763 W5M763 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018080.1|UniProtKB=W5NNH2 W5NNH2 PTHR11232:SF34 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43B scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014917.1|UniProtKB=W5NCL2 W5NCL2 PTHR10127:SF863 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING BONE MORPHOGENETIC PROTEIN 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;dorsal/ventral pattern formation#GO:0009953;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;proteolysis#GO:0006508;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000011628.1|UniProtKB=W5N0Y1 W5N0Y1 PTHR24082:SF15 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of inflammatory response#GO:0050728;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;negative regulation of defense response#GO:0031348;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;negative regulation of nitrogen compound metabolic process#GO:0051172;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of response to stress#GO:0080134;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;positive regulation of RNA metabolic process#GO:0051254;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000005055.1|UniProtKB=W5MCH7 W5MCH7 PTHR12688:SF1 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000012230.1|UniProtKB=W5N343 W5N343 PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001290.1|UniProtKB=W5LZA7 W5LZA7 A3GALT2 PTHR10462:SF33 GLYCOSYLTRANSFERASE-RELATED ALPHA-1,3-GALACTOSYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004815.1|UniProtKB=W5MBP0 W5MBP0 PTHR11347:SF96 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000010932.1|UniProtKB=W5MYF0 W5MYF0 PTHR11799:SF12 PARAOXONASE PARAOXONASE-RELATED metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005411.1|UniProtKB=W5MDS3 W5MDS3 PTHR10288:SF234 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015873.1|UniProtKB=W5NFY6 W5NFY6 PTHR10283:SF65 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006314.1|UniProtKB=W5MGW2 W5MGW2 PTHR10104:SF20 STATHMIN STATHMIN DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000011341.1|UniProtKB=W5MZZ4 W5MZZ4 PTHR22803:SF69 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE MANNOSE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007052.1|UniProtKB=W5MJH5 W5MJH5 PTHR24111:SF4 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000006679.1|UniProtKB=W5MIA6 W5MIA6 PTHR24115:SF328 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1B cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;transport along microtubule#GO:0010970;localization#GO:0051179;axo-dendritic transport#GO:0008088;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011740.1|UniProtKB=W5N1E0 W5N1E0 PTHR19143:SF433 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;complement activation#GO:0006956 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008404.1|UniProtKB=W5MPA4 W5MPA4 PTHR10161:SF28 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 tissue remodeling#GO:0048771;bone remodeling#GO:0046849;tissue homeostasis#GO:0001894;bone resorption#GO:0045453;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;anatomical structure homeostasis#GO:0060249 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003209.1|UniProtKB=W5M5Z0 W5M5Z0 GRIK3 PTHR18966:SF174 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 3 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;sodium channel activity#GO:0005272;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796;Ionotropic glutamate receptor pathway#P00037>KA3#P01002 LEPOC|Ensembl=ENSLOCG00000006080.1|UniProtKB=W5MG33 W5MG33 NXPH4 PTHR17103:SF10 NEUREXOPHILIN NEUREXOPHILIN-4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005859.1|UniProtKB=W5MFB6 W5MFB6 PTHR10766:SF55 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018203.1|UniProtKB=W5NNU5 W5NNU5 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004938.1|UniProtKB=W5MC31 W5MC31 KCNJ6 PTHR11767:SF19 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 LEPOC|Ensembl=ENSLOCG00000007299.1|UniProtKB=W5MKE7 W5MKE7 PTHR22932:SF3 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROSTAGLANDIN E SYNTHASE 3 heat shock protein binding#GO:0031072;protein binding#GO:0005515;isomerase activity#GO:0016853;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;catalytic activity#GO:0003824;Hsp90 protein binding#GO:0051879 telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;gene expression#GO:0010467;icosanoid biosynthetic process#GO:0046456;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;carboxylic acid biosynthetic process#GO:0046394;prostaglandin metabolic process#GO:0006693;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;cellular component assembly#GO:0022607;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;icosanoid metabolic process#GO:0006690;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;unsaturated fatty acid metabolic process#GO:0033559;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;telomere organization#GO:0032200;protein-containing complex assembly#GO:0065003;chaperone-mediated protein complex assembly#GO:0051131;biosynthetic process#GO:0009058;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;unsaturated fatty acid biosynthetic process#GO:0006636;telomere maintenance via telomerase#GO:0007004;protein metabolic process#GO:0019538;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;fatty acid metabolic process#GO:0006631;protein folding#GO:0006457;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010470.1|UniProtKB=W5MWS2 W5MWS2 PTHR22811:SF41 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 5 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009159.1|UniProtKB=W5MS15 W5MS15 PTHR12131:SF1 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004442.1|UniProtKB=W5MAA0 W5MAA0 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017183.1|UniProtKB=W5NKS9 W5NKS9 PTHR47696:SF1 THAP DOMAIN-CONTAINING PROTEIN 2 THAP DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006072.1|UniProtKB=W5MG22 W5MG22 PTHR12011:SF326 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015519.1|UniProtKB=W5NEN8 W5NEN8 PTHR45712:SF11 AGAP008170-PA BIGLYCAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014543.1|UniProtKB=W5NB92 W5NB92 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000967.1|UniProtKB=W5LY81 W5LY81 PTHR23344:SF6 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;regulation of neuron differentiation#GO:0045664;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008783.1|UniProtKB=W5MQN4 W5MQN4 MED10 PTHR13345:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011977.1|UniProtKB=W5N274 W5N274 PTHR11969:SF6 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008651.1|UniProtKB=W5MQ66 W5MQ66 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015975.1|UniProtKB=W5NGB5 W5NGB5 PTHR11814:SF32 SULFATE TRANSPORTER PRESTIN inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012422.1|UniProtKB=W5N3V9 W5N3V9 PTHR45816:SF1 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR LEPOC|Ensembl=ENSLOCG00000004418.1|UniProtKB=W5MA74 W5MA74 PTHR15351:SF2 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-1 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 regulation of biological process#GO:0050789;SREBP signaling pathway#GO:0032933;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012815.1|UniProtKB=W5N558 W5N558 PTHR12113:SF31 DICKKOPF3-LIKE 3 DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007951.1|UniProtKB=W5MMQ0 W5MMQ0 PTHR23112:SF43 G PROTEIN-COUPLED RECEPTOR 157-RELATED CYCLIC AMP RECEPTOR-LIKE PROTEIN A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017209.1|UniProtKB=W5NKW7 W5NKW7 PTHR12045:SF3 ALLANTOICASE INACTIVE ALLANTOICASE-RELATED Allantoin degradation#P02725>Allantoate amidohydrolase#P02821 LEPOC|Ensembl=ENSLOCG00000007756.1|UniProtKB=W5MM10 W5MM10 PTHR11442:SF41 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ZETA antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000012713.1|UniProtKB=W5N4T6 W5N4T6 PTHR16056:SF18 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle microtubule#GO:0005876;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000011756.1|UniProtKB=W5N1E9 W5N1E9 PTHR12064:SF22 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;establishment of localization#GO:0051234;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001602.1|UniProtKB=W5M0D9 W5M0D9 PTHR24339:SF34 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001173.1|UniProtKB=W5LYW1 W5LYW1 OXT PTHR11681:SF5 NEUROPHYSIN ISOTOCIN neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;secretory vesicle#GO:0099503;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 neuropeptide#PC00162;peptide hormone#PC00179 Opioid prodynorphin pathway#P05916>provasopressin#P05999;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Signal Peptide#P04597;Opioid prodynorphin pathway#P05916>vasopressin#P06000;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>prepropressophysin#G06048;Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Vasopressin synthesis#P04395>Glycopeptide#P04593;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595;Vasopressin synthesis#P04395>Neurophysin#P04594 LEPOC|Ensembl=ENSLOCG00000000874.1|UniProtKB=W5LXW5 W5LXW5 PTHR24377:SF929 IP01015P-RELATED ZINC FINGER PROTEIN 665 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011528.1|UniProtKB=W5N0K9 W5N0K9 PTHR12385:SF12 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009971.1|UniProtKB=W5MUY0 W5MUY0 PTHR36290:SF1 RIKEN CDNA D630039A03 GENE RIKEN CDNA D630039A03 GENE LEPOC|Ensembl=ENSLOCG00000015267.1|UniProtKB=W5NDS8 W5NDS8 PTHR47078:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000017396.1|UniProtKB=W5NLJ2 W5NLJ2 PTHR24369:SF219 ANTIGEN BSP, PUTATIVE-RELATED CARBOXYPEPTIDASE N SUBUNIT 2-LIKE ISOFORM X1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009587.1|UniProtKB=W5MTK2 W5MTK2 PTHR23309:SF49 3-HYDROXYACYL-COA DEHYROGENASE PEROXISOMAL BIFUNCTIONAL ENZYME oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013485.1|UniProtKB=W5N7M5 W5N7M5 PTHR10013:SF0 GENERAL VESICULAR TRANSPORT FACTOR P115 GENERAL VESICULAR TRANSPORT FACTOR P115 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010461.1|UniProtKB=W5MWR0 W5MWR0 PTHR15907:SF122 DUF614 FAMILY PROTEIN-RELATED PLAC8-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016996.1|UniProtKB=W5NK50 W5NK50 ZNF451 PTHR24403:SF103 ZINC FINGER PROTEIN E3 SUMO-PROTEIN LIGASE ZNF451 ISOFORM X1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003977.1|UniProtKB=W5M8P5 W5M8P5 PTHR45819:SF3 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;ribonucleoside triphosphate phosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;negative regulation of apoptotic process#GO:0043066;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000007954.1|UniProtKB=W5MMQ2 W5MMQ2 PTHR10574:SF28 NETRIN/LAMININ-RELATED NETRIN-G1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 LEPOC|Ensembl=ENSLOCG00000000176.1|UniProtKB=W5LVN9 W5LVN9 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013086.1|UniProtKB=W5N661 W5N661 PTHR11551:SF6 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 1 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 PI3 kinase pathway#P00048>IGFBP1#G01543 LEPOC|Ensembl=ENSLOCG00000012225.1|UniProtKB=W5N329 W5N329 RASSF5 PTHR22738:SF9 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013858.1|UniProtKB=W5N8Y7 W5N8Y7 PTHR47448:SF2 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002936.1|UniProtKB=W5M4Z8 W5M4Z8 PTHR11848:SF43 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 6 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000009095.1|UniProtKB=W5MRT0 W5MRT0 PTHR13832:SF699 PROTEIN PHOSPHATASE 2C INTEGRIN-LINKED KINASE-ASSOCIATED SERINE_THREONINE PHOSPHATASE 2C macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007726.1|UniProtKB=W5MLX6 W5MLX6 PTHR21595:SF1 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein depolymerization#GO:1901879;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001054.1|UniProtKB=W5LYH9 W5LYH9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007103.1|UniProtKB=W5MJP1 W5MJP1 PTHR11309:SF23 FRIZZLED FRIZZLED-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000001423.1|UniProtKB=W5LZR4 W5LZR4 PTHR12258:SF11 JANUS-A/JANUS-B 14 KDA PHOSPHOHISTIDINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015882.1|UniProtKB=W5NFZ8 W5NFZ8 PTHR10300:SF5 CALCIPRESSIN CALCIPRESSIN-2 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013519.1|UniProtKB=W5N7R3 W5N7R3 PTHR19265:SF0 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013450.1|UniProtKB=W5N7H3 W5N7H3 PTHR47977:SF20 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 positive regulation of secretion#GO:0051047;transport#GO:0006810;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;export from cell#GO:0140352;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000595.1|UniProtKB=W5LX02 W5LX02 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000001099.1|UniProtKB=W5LYN2 W5LYN2 PTHR19282:SF440 TETRASPANIN PERIPHERIN-2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014317.1|UniProtKB=W5NAH2 W5NAH2 PTHR10177:SF214 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B3 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000001120.1|UniProtKB=W5LYQ3 W5LYQ3 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015868.1|UniProtKB=W5NFX8 W5NFX8 PTHR24103:SF673 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015661.1|UniProtKB=W5NF88 W5NF88 PTHR10183:SF268 CALPAIN CALPAIN-2 CATALYTIC SUBUNIT cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000000736.1|UniProtKB=W5LXF5 W5LXF5 PTHR12080:SF80 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003907.1|UniProtKB=W5M8F2 W5M8F2 PTHR16705:SF12 COMPLEXIN COMPLEXIN-3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;SNARE complex#GO:0031201;cell junction#GO:0030054;terminal bouton#GO:0043195;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000014908.1|UniProtKB=W5NCK2 W5NCK2 PTHR11036:SF80 SEMAPHORIN SEMAPHORIN-7A molecular function activator activity#GO:0140677;integrin binding#GO:0005178;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;integrin-mediated signaling pathway#GO:0007229;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of defense response#GO:0031347;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;generation of neurons#GO:0048699;cell migration#GO:0016477 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005154.1|UniProtKB=W5MD03 W5MD03 PTHR11226:SF1 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 2 UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;protein binding#GO:0005515;glucosyltransferase activity#GO:0046527;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein N-linked glycosylation#GO:0006487;cellular response to stress#GO:0033554;glycosylation#GO:0070085 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014966.1|UniProtKB=W5NCR6 W5NCR6 PTHR22967:SF101 SERINE/THREONINE PROTEIN KINASE AP2-ASSOCIATED KINASE 1B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of Notch signaling pathway#GO:0008593;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of receptor-mediated endocytosis#GO:0048259 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013552.1|UniProtKB=W5N7U9 W5N7U9 PTHR43391:SF72 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016826.1|UniProtKB=W5NJI9 W5NJI9 PTHR14209:SF19 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000006220.1|UniProtKB=W5MGJ9 W5MGJ9 PTHR19433:SF137 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001742.1|UniProtKB=W5M0V3 W5M0V3 RASL10B PTHR46350:SF2 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS LIKE FAMILY 10 MEMBER B LEPOC|Ensembl=ENSLOCG00000004164.1|UniProtKB=W5M9C0 W5M9C0 PTHR11346:SF21 GALECTIN GRIFIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000011328.1|UniProtKB=W5MZW1 W5MZW1 PTHR22974:SF20 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;chromosome segregation#GO:0007059;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010075.1|UniProtKB=W5MVC0 W5MVC0 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000000752.1|UniProtKB=W5LXK6 W5LXK6 PTHR10411:SF5 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000006791.1|UniProtKB=W5MIJ5 W5MIJ5 PTHR41693:SF3 HEME-BINDING PROTEIN 1 SI:CH211-76L23.4 LEPOC|Ensembl=ENSLOCG00000008153.1|UniProtKB=W5MND7 W5MND7 PTHR24245:SF6 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 26 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010192.1|UniProtKB=W5MVS3 W5MVS3 PTHR11860:SF118 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008533.1|UniProtKB=W5MPR8 W5MPR8 PTHR47109:SF1 NUCLEOREDOXIN-LIKE PROTEIN 1 NUCLEOREDOXIN-LIKE PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014958.1|UniProtKB=W5NCQ8 W5NCQ8 PTHR16105:SF2 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING PROTEIN 41 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;U12-type spliceosomal complex#GO:0005689 LEPOC|Ensembl=ENSLOCG00000015207.1|UniProtKB=W5NDK3 W5NDK3 PTHR28358:SF1 TRANSMEMBRANE PROTEIN 127 TRANSMEMBRANE PROTEIN 127 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009828.1|UniProtKB=W5MUF7 W5MUF7 PTHR24064:SF198 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 13 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011561.1|UniProtKB=W5N0P7 W5N0P7 ANXA7 PTHR10502:SF239 ANNEXIN ANNEXIN A7 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000010240.1|UniProtKB=W5MVY5 W5MVY5 PTHR24213:SF6 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;cellular component organization#GO:0016043;plasma membrane bounded cell projection assembly#GO:0120031;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000004257.1|UniProtKB=W5M9N2 W5M9N2 PTHR12245:SF3 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016395.1|UniProtKB=W5NHY8 W5NHY8 PTHR11036:SF22 SEMAPHORIN SEMAPHORIN-3E molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008991.1|UniProtKB=W5MRE4 W5MRE4 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000010936.1|UniProtKB=W5MYF3 W5MYF3 PTHR45998:SF2 SERINE/THREONINE-PROTEIN KINASE 16 SERINE_THREONINE-PROTEIN KINASE 16 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012660.1|UniProtKB=W5N4M2 W5N4M2 PTHR21290:SF24 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;phosphate-containing compound metabolic process#GO:0006796;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004352.1|UniProtKB=W5M9Z3 W5M9Z3 PTHR47960:SF7 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 RNA HELICASE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;non-membrane-bounded organelle assembly#GO:0140694;P-body assembly#GO:0033962;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000015306.1|UniProtKB=W5NDX4 W5NDX4 PTHR14297:SF4 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER XK-RELATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000008340.1|UniProtKB=W5MP18 W5MP18 PTHR10969:SF54 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000006698.1|UniProtKB=W5MI79 W5MI79 PTHR14132:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 6-RELATED transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transporter activity#GO:0032409 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004997.1|UniProtKB=W5MCC9 W5MCC9 PTHR24271:SF88 KALLIKREIN-RELATED MAST CELL PROTEASE 2 ISOFORM X1 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005939.1|UniProtKB=W5MFL2 W5MFL2 PTHR12176:SF80 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE METHYLTRANSFERASE 4 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000001010.1|UniProtKB=W5LYD3 W5LYD3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013600.1|UniProtKB=W5N810 W5N810 PTHR10985:SF135 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT RELATED-7 ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014986.1|UniProtKB=W5NCU1 W5NCU1 PTHR24232:SF83 G-PROTEIN COUPLED RECEPTOR GENE 5127-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003421.1|UniProtKB=W5M6N8 W5M6N8 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008208.1|UniProtKB=W5MNK5 W5MNK5 PTHR46881:SF1 PALMDELPHIN PALMDELPHIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004696.1|UniProtKB=W5MB66 W5MB66 PTHR19134:SF550 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002112.1|UniProtKB=W5M242 W5M242 PTHR45616:SF4 GATA-TYPE DOMAIN-CONTAINING PROTEIN THREAD BIOPOLYMER FILAMENT SUBUNIT ALPHA LEPOC|Ensembl=ENSLOCG00000016132.1|UniProtKB=W5NGW8 W5NGW8 PTHR11224:SF37 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015621.1|UniProtKB=W5NF19 W5NF19 PTHR10332:SF9 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018355.1|UniProtKB=W5NP97 W5NP97 PTHR22639:SF3 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000011729.1|UniProtKB=W5N1B5 W5N1B5 PTHR24289:SF14 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE CYTOCHROME P450, FAMILY 17, SUBFAMILY A, POLYPEPTIDE 1 lyase activity#GO:0016829;steroid hydroxylase activity#GO:0008395;carbon-carbon lyase activity#GO:0016830;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;hormone metabolic process#GO:0042445;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000014569.1|UniProtKB=W5NBB8 W5NBB8 PTHR13116:SF11 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000002980.1|UniProtKB=W5M545 W5M545 PTHR15740:SF1 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007745.1|UniProtKB=W5MLZ3 W5MLZ3 HBA2 PTHR11442:SF48 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000003497.1|UniProtKB=W5M6Y1 W5M6Y1 PTHR46878:SF1 FORKHEAD BOX PROTEIN M1 FORKHEAD BOX PROTEIN M1 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000014410.1|UniProtKB=W5NAT1 W5NAT1 PTHR11844:SF24 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 2 peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000010264.1|UniProtKB=W5MW08 W5MW08 TAFA3 PTHR31770:SF3 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000005742.1|UniProtKB=W5MEX7 W5MEX7 PTHR11339:SF374 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED ZONADHESIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006739.1|UniProtKB=W5MID1 W5MID1 PTHR23503:SF54 SOLUTE CARRIER FAMILY 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011165.1|UniProtKB=W5MZA8 W5MZA8 PTHR23037:SF22 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immunoglobulin mediated immune response#GO:0016064;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;leukocyte mediated immunity#GO:0002443;cell communication#GO:0007154;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 LEPOC|Ensembl=ENSLOCG00000010820.1|UniProtKB=W5MY08 W5MY08 ATG2B PTHR13190:SF20 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 HOMOLOG B phosphatidylinositol-3-phosphate binding#GO:0032266;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component assembly#GO:0022607;microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011214.1|UniProtKB=W5MZG5 W5MZG5 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009355.1|UniProtKB=W5MSQ6 W5MSQ6 PTHR13964:SF26 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000000021.1|UniProtKB=W5LV66 W5LV66 PTHR12027:SF84 WNT RELATED PROTEIN WNT-9B molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000003232.1|UniProtKB=W5M609 W5M609 PTHR12876:SF10 N4BP1-RELATED ENDORIBONUCLEASE ZC3H12A catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of mRNA metabolic process#GO:1903313;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of mRNA catabolic process#GO:0061014;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;mRNA destabilization#GO:0061157;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010806.1|UniProtKB=W5MXY4 W5MXY4 PTHR45617:SF172 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014842.1|UniProtKB=W5NCB9 W5NCB9 PTHR22957:SF621 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2B nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000000556.1|UniProtKB=W5LWV7 W5LWV7 PTHR21063:SF4 LFA-3 CD48 ANTIGEN-RELATED LEPOC|Ensembl=ENSLOCG00000006152.1|UniProtKB=W5MGC6 W5MGC6 PTHR12268:SF19 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN ALPHA biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008964.1|UniProtKB=W5MRB2 W5MRB2 PTHR23070:SF110 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 LEPOC|Ensembl=ENSLOCG00000017227.1|UniProtKB=W5NKZ8 W5NKZ8 PTHR13123:SF8 LD30288P F-BOX ONLY PROTEIN 25 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003691.1|UniProtKB=W5M7U1 W5M7U1 PTHR10807:SF4 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 13 nucleoside-triphosphatase regulator activity#GO:0060589;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;GTPase regulator activity#GO:0030695;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;guanyl-nucleotide exchange factor activity#GO:0005085 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013030.1|UniProtKB=W5N5Z5 W5N5Z5 PTHR16096:SF8 MICROTUBULE-ASSOCIATED PROTEIN 11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 14 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;alpha-tubulin binding#GO:0043014;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPP complex#GO:0030008;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010648.1|UniProtKB=W5MXD4 W5MXD4 PTHR13793:SF79 PHD FINGER PROTEINS PROTEIN JADE-1 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011743.1|UniProtKB=W5N1E1 W5N1E1 PTHR11533:SF276 PROTEASE M1 ZINC METALLOPROTEASE GLUTAMYL AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001919.1|UniProtKB=W5M1H5 W5M1H5 SERINC3 PTHR10383:SF51 SERINE INCORPORATOR SERINE INCORPORATOR 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010126.1|UniProtKB=W5MVI5 W5MVI5 PTHR24278:SF37 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016449.1|UniProtKB=W5NI58 W5NI58 PTHR11630:SF47 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM8 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;single-stranded DNA helicase activity#GO:0017116;catalytic activity, acting on DNA#GO:0140097 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000017276.1|UniProtKB=W5NL60 W5NL60 EPB41L2 PTHR23280:SF41 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 2 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000013230.1|UniProtKB=W5N6P4 W5N6P4 PTHR11827:SF93 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;sodium ion homeostasis#GO:0055078;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;apical part of cell#GO:0045177 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003630.1|UniProtKB=W5M7F7 W5M7F7 PTHR28588:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008938.1|UniProtKB=W5MR78 W5MR78 PTHR46755:SF5 METHIONINE-R-SULFOXIDE REDUCTASE B1 METHIONINE-R-SULFOXIDE REDUCTASE B1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007322.1|UniProtKB=W5MKF9 W5MKF9 PTHR12320:SF1 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002379.1|UniProtKB=W5M333 W5M333 PTHR22913:SF6 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 3 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosaminoglycan metabolic process#GO:0030203;cellular component assembly#GO:0022607;carbohydrate biosynthetic process#GO:0016051;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;polysaccharide metabolic process#GO:0005976;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000011777.1|UniProtKB=W5N1H2 W5N1H2 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000615.1|UniProtKB=W5LX19 W5LX19 PTHR19956:SF5 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intermediate filament#GO:0005882;intracellular organelle lumen#GO:0070013;intermediate filament cytoskeleton#GO:0045111;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;nuclear periphery#GO:0034399;non-membrane-bounded organelle#GO:0043228;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000001059.1|UniProtKB=W5LYI7 W5LYI7 PTHR12767:SF5 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER B LEPOC|Ensembl=ENSLOCG00000017293.1|UniProtKB=W5NL89 W5NL89 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010079.1|UniProtKB=W5MVC5 W5MVC5 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000006713.1|UniProtKB=W5MI99 W5MI99 NUP210L PTHR23019:SF1 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210-LIKE envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004992.1|UniProtKB=W5MCA2 W5MCA2 PTHR46346:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009411.1|UniProtKB=W5MSX6 W5MSX6 PTHR10926:SF68 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006391.1|UniProtKB=W5MH60 W5MH60 PTHR12400:SF51 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000002505.1|UniProtKB=W5M3J3 W5M3J3 PTHR11417:SF3 SOMATOTROPIN,PROLACTIN SOMATOLACTIN ALPHA ISOFORM X1-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to peptide hormone#GO:0043434;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;regulation of growth#GO:0040008;cellular response to nitrogen compound#GO:1901699;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;response to nutrient levels#GO:0031667;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to hormone#GO:0009725;response to chemical#GO:0042221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000000125.1|UniProtKB=W5LVL6 W5LVL6 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000004107.1|UniProtKB=W5M969 W5M969 PTHR23280:SF12 4.1 G PROTEIN PROTEIN 4.1 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Nicotine pharmacodynamics pathway#P06587>EPB41#P06607;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 LEPOC|Ensembl=ENSLOCG00000008323.1|UniProtKB=W5MP05 W5MP05 PTHR12845:SF2 GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN-RELATED regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011232.1|UniProtKB=W5MZK2 W5MZK2 PTHR11849:SF196 ETS ETS TRANSLOCATION VARIANT 1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000002199.1|UniProtKB=W5M2F2 W5M2F2 PTHR24027:SF80 CADHERIN-23 CADHERIN-13 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000000617.1|UniProtKB=W5LX20 W5LX20 PTHR11661:SF1 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017084.1|UniProtKB=W5NKF3 W5NKF3 PTHR16515:SF21 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006638.1|UniProtKB=W5MI10 W5MI10 PTHR10201:SF20 MATRIX METALLOPROTEINASE STROMELYSIN-3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016903.1|UniProtKB=W5NJT4 W5NJT4 PTHR23166:SF3 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN-A-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017103.1|UniProtKB=W5NKH5 W5NKH5 STMP1 PTHR47709:SF2 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009956.1|UniProtKB=W5MUW7 W5MUW7 PTHR39490:SF8 ARRESTIN DOMAIN-CONTAINING PROTEIN D ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21 LEPOC|Ensembl=ENSLOCG00000006958.1|UniProtKB=W5MJ63 W5MJ63 PTHR45729:SF11 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAINS, DELTA neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;regulation of secretion by cell#GO:1903530;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cell communication#GO:0007154;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;signal release from synapse#GO:0099643;regulation of transport#GO:0051049;exocytosis#GO:0006887;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment of localization in cell#GO:0051649;cell-cell signaling#GO:0007267;signaling#GO:0023052;export from cell#GO:0140352;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003288.1|UniProtKB=W5M676 W5M676 PTHR11349:SF49 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 LEPOC|Ensembl=ENSLOCG00000016860.1|UniProtKB=W5NJN5 W5NJN5 MOCS3 PTHR10953:SF102 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001116.1|UniProtKB=W5LYQ2 W5LYQ2 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016596.1|UniProtKB=W5NIP1 W5NIP1 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG protein transmembrane transporter activity#GO:0008320;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015619.1|UniProtKB=W5NF17 W5NF17 ENKD1 PTHR21490:SF2 ENKURIN-RELATED ENKURIN DOMAIN-CONTAINING PROTEIN 1 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014261.1|UniProtKB=W5NA97 W5NA97 STK26 PTHR48012:SF7 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 26 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;macromolecule modification#GO:0043412;regulation of locomotion#GO:0040012;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;negative regulation of cell motility#GO:2000146;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006335.1|UniProtKB=W5MGZ3 W5MGZ3 TAF4B PTHR15138:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 4 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000004833.1|UniProtKB=W5MBP4 W5MBP4 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016175.1|UniProtKB=W5NH26 W5NH26 PTHR12756:SF12 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE-LIKE PROTEIN 5 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001309.1|UniProtKB=W5LZD5 W5LZD5 PTHR15434:SF2 HEAT SHOCK FACTOR 2-BINDING PROTEIN HEAT SHOCK FACTOR 2-BINDING PROTEIN cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014866.1|UniProtKB=W5NCE9 W5NCE9 PTHR16134:SF1 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH PROTEIN 22 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012143.1|UniProtKB=W5N2S9 W5N2S9 PTHR12170:SF6 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5B transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000879.1|UniProtKB=W5LXX3 W5LXX3 ITGB1 PTHR10082:SF28 INTEGRIN BETA SUBUNIT INTEGRIN BETA-1 extracellular matrix binding#GO:0050840;integrin binding#GO:0005178;binding#GO:0005488;cytokine binding#GO:0019955;collagen binding#GO:0005518;cell adhesion molecule binding#GO:0050839;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 CCKR signaling map#P06959>ITGB1#G07277;CCKR signaling map#P06959>ITGB1#P07113;Integrin signalling pathway#P00034>Integrin beta#P00931;CCKR signaling map#P06959>ITGB1#G06984;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 LEPOC|Ensembl=ENSLOCG00000012467.1|UniProtKB=W5N3Z1 W5N3Z1 PTHR45732:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8A localization#GO:0051179;axo-dendritic transport#GO:0008088;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012911.1|UniProtKB=W5N5J4 W5N5J4 TM6SF1 PTHR14568:SF10 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 1 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004502.1|UniProtKB=W5MAG9 W5MAG9 PTHR31573:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2 DNA OXIDATIVE DEMETHYLASE ALKBH2 ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;catalytic activity, acting on a nucleic acid#GO:0140640;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;cation binding#GO:0043169;demethylase activity#GO:0032451;iron ion binding#GO:0005506;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;ion binding#GO:0043167 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;DNA modification#GO:0006304;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008213.1|UniProtKB=W5MNL2 W5MNL2 RWDD3 PTHR15628:SF1 RWD DOMAIN-CONTAINING PROTEIN 3 RWD DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000004054.1|UniProtKB=W5M8Y8 W5M8Y8 PTHR11834:SF4 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;embryonic organ development#GO:0048568;hippo signaling#GO:0035329;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000002704.1|UniProtKB=W5M475 W5M475 PTHR13318:SF44 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000000605.1|UniProtKB=W5LX07 W5LX07 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012673.1|UniProtKB=W5N4N7 W5N4N7 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649 LEPOC|Ensembl=ENSLOCG00000011854.1|UniProtKB=W5N1S5 W5N1S5 PTHR24056:SF510 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017258.1|UniProtKB=W5NL37 W5NL37 PTHR10340:SF24 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018157.1|UniProtKB=W5NNP9 W5NNP9 PTHR22902:SF15 SESQUIPEDALIAN SESQUIPEDALIAN-2 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule metabolic process#GO:0043170;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006016.1|UniProtKB=W5MFV5 W5MFV5 PTHR26451:SF866 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016997.1|UniProtKB=W5NK52 W5NK52 PTHR12334:SF6 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000020981.1|UniProtKB=Q8HQN1 Q8HQN1 COI PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular metabolic process#GO:0044237;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;respiratory electron transport chain#GO:0022904;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152 oxidase#PC00175;oxidoreductase#PC00176 ATP synthesis#P02721>Cytochrome oxidase aa3#P02793 LEPOC|Ensembl=ENSLOCG00000011315.1|UniProtKB=W5MZU6 W5MZU6 PTHR14208:SF7 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000008529.1|UniProtKB=W5MPR6 W5MPR6 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007840.1|UniProtKB=W5MMB2 W5MMB2 PTHR45677:SF5 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 1 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000014561.1|UniProtKB=W5NBB0 W5NBB0 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000934.1|UniProtKB=W5LY73 W5LY73 PTHR24343:SF540 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE CHK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018236.1|UniProtKB=W5NNX8 W5NNX8 PTHR10605:SF18 HEPARAN SULFATE SULFOTRANSFERASE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010431.1|UniProtKB=W5MWM7 W5MWM7 PTHR11639:SF141 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-B cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167;signaling receptor binding#GO:0005102 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;regulation of cell population proliferation#GO:0042127;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017781.1|UniProtKB=W5NMM6 W5NMM6 PCDH20 PTHR24028:SF260 CADHERIN-87A PROTOCADHERIN-20 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000004302.1|UniProtKB=W5M9T3 W5M9T3 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010197.1|UniProtKB=W5MVS9 W5MVS9 PTHR45684:SF20 RE74312P GTP-BINDING PROTEIN SAR1B pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;positive regulation of protein transport#GO:0051222;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;positive regulation of establishment of protein localization#GO:1904951;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;positive regulation of protein localization#GO:1903829;regulation of establishment of protein localization#GO:0070201 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000013940.1|UniProtKB=W5N977 W5N977 PTHR23049:SF58 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000004006.1|UniProtKB=W5M8U1 W5M8U1 PTHR21694:SF35 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 1 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000003283.1|UniProtKB=W5M690 W5M690 PTHR10027:SF14 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion-gated channel activity#GO:0022839;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014139.1|UniProtKB=W5N9V6 W5N9V6 PTHR15730:SF5 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED SI:CH211-210B2.2-RELATED LEPOC|Ensembl=ENSLOCG00000005992.1|UniProtKB=W5MFT1 W5MFT1 SNAI2 PTHR24388:SF42 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003364.1|UniProtKB=W5M6I3 W5M6I3 PTHR43340:SF5 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;transferase activity#GO:0016740;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;IMP metabolic process#GO:0046040;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247 LEPOC|Ensembl=ENSLOCG00000013900.1|UniProtKB=W5N931 W5N931 PTHR46899:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000007449.1|UniProtKB=W5ML05 W5ML05 PTHR10749:SF5 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, LIVER ISOFORM cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000008399.1|UniProtKB=W5MP97 W5MP97 PTHR45726:SF2 LEUKOTRIENE A-4 HYDROLASE AMINOPEPTIDASE RNPEPL1 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloaminopeptidase activity#GO:0070006 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000001719.1|UniProtKB=W5M0S3 W5M0S3 CTU1 PTHR11807:SF12 ATPASES OF THE PP SUPERFAMILY-RELATED CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004276.1|UniProtKB=W5M9Q6 W5M9Q6 PTHR10334:SF64 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016513.1|UniProtKB=W5NID8 W5NID8 PTHR13417:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF146 E3 UBIQUITIN-PROTEIN LIGASE RNF146 carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015737.1|UniProtKB=W5NFG7 W5NFG7 AMDHD1 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002262.1|UniProtKB=W5M2P6 W5M2P6 PTHR10288:SF340 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013748.1|UniProtKB=W5N8J4 W5N8J4 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML45 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000338.1|UniProtKB=W5LW63 W5LW63 AVPR2 PTHR24241:SF20 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V2 RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;response to organic substance#GO:0010033;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;system process#GO:0003008;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011673.1|UniProtKB=W5N135 W5N135 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004183.1|UniProtKB=W5M9E2 W5M9E2 PTHR15651:SF7 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ARMADILLO REPEAT-CONTAINING PROTEIN 8 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000001303.1|UniProtKB=W5LZC1 W5LZC1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000018119.1|UniProtKB=W5NNL1 W5NNL1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014451.1|UniProtKB=W5NAX7 W5NAX7 PTHR47225:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003695.1|UniProtKB=W5M7Q2 W5M7Q2 PTHR13265:SF1 THO COMPLEX SUBUNIT 1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001274.1|UniProtKB=W5LZ89 W5LZ89 PTHR32017:SF3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;outer kinetochore#GO:0000940;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000003495.1|UniProtKB=W5M6Z1 W5M6Z1 PTHR46160:SF9 ALPHA-TECTORIN-RELATED PROTEIN PRY2-RELATED LEPOC|Ensembl=ENSLOCG00000002443.1|UniProtKB=W5M3B3 W5M3B3 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002650.1|UniProtKB=W5M406 W5M406 PTHR46252:SF1 BRORIN FAMILY MEMBER VON WILLEBRAND FACTOR C DOMAIN-CONTAINING PROTEIN 2-LIKE regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;monoatomic ion channel complex#GO:0034702;extracellular region#GO:0005576;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003744.1|UniProtKB=W5M7X6 W5M7X6 PTHR15711:SF3 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 LEPOC|Ensembl=ENSLOCG00000000185.1|UniProtKB=W5LVQ0 W5LVQ0 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000003139.1|UniProtKB=W5M5N8 W5M5N8 PTHR13483:SF11 BOX C_D SNORNA PROTEIN 1-RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of LSU-rRNA#GO:0000470 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004968.1|UniProtKB=W5MC67 W5MC67 PTHR24241:SF143 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RFAMIDE PEPTIDE RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015812.1|UniProtKB=W5NFQ8 W5NFQ8 PTHR12701:SF5 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 29 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017376.1|UniProtKB=W5NLH2 W5NLH2 PTHR24231:SF49 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013432.1|UniProtKB=W5N7F2 W5N7F2 HOXB1 PTHR45946:SF5 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-B1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015487.1|UniProtKB=W5NEK1 W5NEK1 SRPK2 PTHR24055:SF578 MITOGEN-ACTIVATED PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT BUD32 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010479.1|UniProtKB=W5MWU4 W5MWU4 PTHR45915:SF3 TRANSCRIPTION INTERMEDIARY FACTOR E3 UBIQUITIN-PROTEIN LIGASE TRIM33 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016125.1|UniProtKB=W5NGW0 W5NGW0 PTHR32005:SF1 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178B cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006538.1|UniProtKB=W5MHP0 W5MHP0 PTHR21191:SF7 AQUAPORIN AQUAPORIN-11 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011762.1|UniProtKB=W5N1F7 W5N1F7 CBX3 PTHR22812:SF134 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008424.1|UniProtKB=W5MPH6 W5MPH6 PTHR23192:SF70 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006428.1|UniProtKB=W5MHA8 W5MHA8 PTHR12628:SF6 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD FINGER PROTEIN 19 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004667.1|UniProtKB=W5MB30 W5MB30 PTHR10379:SF6 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T3 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000014934.1|UniProtKB=W5NCM7 W5NCM7 PTHR13058:SF22 THREE PRIME REPAIR EXONUCLEASE 1, 2 EXODEOXYRIBONUCLEASE III hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002751.1|UniProtKB=W5M4C9 W5M4C9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016998.1|UniProtKB=W5NK53 W5NK53 PTHR46253:SF2 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 2 protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 p38 MAPK pathway#P05918>TAB2#P06033 LEPOC|Ensembl=ENSLOCG00000006355.1|UniProtKB=W5MH20 W5MH20 PTHR23220:SF26 INTEGRIN ALPHA INTEGRIN ALPHA-10 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000004816.1|UniProtKB=W5MBN1 W5MBN1 PTHR11037:SF11 TRANSCRIPTION FACTOR CP2 ALPHA-GLOBIN TRANSCRIPTION FACTOR CP2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010468.1|UniProtKB=W5MWT0 W5MWT0 PTHR10819:SF3 PHOSPHOTRIESTERASE-RELATED PHOSPHOTRIESTERASE-RELATED PROTEIN esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000000988.1|UniProtKB=W5LYA4 W5LYA4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003599.1|UniProtKB=W5M7A7 W5M7A7 PTHR11685:SF314 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19B ISOFORM X1-RELATED ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;autophagy of mitochondrion#GO:0000422;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of mitochondrion organization#GO:0010821;proteolysis#GO:0006508;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;cellular catabolic process#GO:0044248;regulation of apoptotic process#GO:0042981;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organelle disassembly#GO:1903008;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006783.1|UniProtKB=W5MII9 W5MII9 PTHR21328:SF3 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP8 protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;pentosyltransferase activity#GO:0016763;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;protein serine/threonine kinase activator activity#GO:0043539;protein binding#GO:0005515 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 envelope#GO:0031975;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000012699.1|UniProtKB=W5N4S4 W5N4S4 PTHR46392:SF1 DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE DUAL SERINE_THREONINE AND TYROSINE PROTEIN KINASE regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;response to fibroblast growth factor#GO:0071774;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to endogenous stimulus#GO:0071495;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014727.1|UniProtKB=W5NBX3 W5NBX3 PTHR16188:SF4 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14A phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000017743.1|UniProtKB=W5NMI8 W5NMI8 PTHR11006:SF73 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012937.1|UniProtKB=W5N5M4 W5N5M4 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004584.1|UniProtKB=W5MAS7 W5MAS7 C6orf62 PTHR28336:SF3 BA1-643 CHROMOSOME 11 C6ORF62 HOMOLOG LEPOC|Ensembl=ENSLOCG00000016206.1|UniProtKB=W5NH67 W5NH67 PTHR47249:SF1 VACUOLAR PROTEIN 8 VACUOLAR PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000010710.1|UniProtKB=W5MXL6 W5MXL6 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of chromosome organization#GO:0033044;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003771.1|UniProtKB=W5M806 W5M806 PTHR44167:SF24 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE CHK2 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>Chk2#P01484 LEPOC|Ensembl=ENSLOCG00000013895.1|UniProtKB=W5N929 W5N929 MTUS1 PTHR24200:SF7 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005223.1|UniProtKB=W5MD40 W5MD40 PTHR11959:SF12 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003633.1|UniProtKB=W5M7E7 W5M7E7 PTHR35258:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000011826.1|UniProtKB=W5N1N3 W5N1N3 PTHR19282:SF470 TETRASPANIN TETRASPANIN-17 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013932.1|UniProtKB=W5N969 W5N969 PTHR13678:SF2 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002009.1|UniProtKB=W5M1T1 W5M1T1 PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014114.1|UniProtKB=W5N9T0 W5N9T0 PTHR15960:SF3 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1-LIKE protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000002642.1|UniProtKB=W5M415 W5M415 MUSK PTHR24416:SF317 TYROSINE-PROTEIN KINASE RECEPTOR MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;Wnt-protein binding#GO:0017147;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006283.1|UniProtKB=W5MGT2 W5MGT2 PTHR22891:SF46 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;male gamete generation#GO:0048232;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;spermatogenesis#GO:0007283;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;regulatory ncRNA-mediated gene silencing#GO:0031047;gamete generation#GO:0007276;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;negative regulation of macromolecule biosynthetic process#GO:0010558;piRNA processing#GO:0034587;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000014466.1|UniProtKB=W5NAZ8 W5NAZ8 PTHR22624:SF35 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4A cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;mitophagy#GO:0000423;protein modification process#GO:0036211;gene expression#GO:0010467;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010339.1|UniProtKB=W5MWA9 W5MWA9 PTHR47006:SF1 STAR-RELATED LIPID TRANSFER PROTEIN 4 STAR-RELATED LIPID TRANSFER PROTEIN 4 cholesterol transfer activity#GO:0120020;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;intracellular sterol transport#GO:0032366;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;intracellular cholesterol transport#GO:0032367;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;establishment of localization#GO:0051234;maintenance of location#GO:0051235;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;lipid storage#GO:0019915;intracellular lipid transport#GO:0032365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015553.1|UniProtKB=W5NET8 W5NET8 PTHR24240:SF16 OPSIN SHORT-WAVE-SENSITIVE OPSIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005587.1|UniProtKB=W5MED7 W5MED7 ISYNA1 PTHR11510:SF5 MYO-INOSITOL-1 PHOSPHATE SYNTHASE INOSITOL-3-PHOSPHATE SYNTHASE 1 isomerase activity#GO:0016853;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;alcohol biosynthetic process#GO:0046165;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016410.1|UniProtKB=W5NI07 W5NI07 PTHR45951:SF4 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 1 amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013742.1|UniProtKB=W5N8J1 W5N8J1 PTHR10454:SF198 CASPASE CASPASE-3 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 neurogenesis#GO:0022008;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;nervous system development#GO:0007399;skin development#GO:0043588;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;epidermis development#GO:0008544;positive regulation of programmed cell death#GO:0043068;apoptotic process#GO:0006915;cell death#GO:0008219;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;epidermal cell differentiation#GO:0009913;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;programmed cell death#GO:0012501;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;erythrocyte differentiation#GO:0030218;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;immune system process#GO:0002376;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Pro-Caspase3#P00608;FAS signaling pathway#P00020>Caspase3#P00599;CCKR signaling map#P06959>Pro-caspase-3#P07231;CCKR signaling map#P06959>Caspase-3#P07108;Huntington disease#P00029>Caspase 3#P00812;Apoptosis signaling pathway#P00006>Caspase 3#P00305 LEPOC|Ensembl=ENSLOCG00000002552.1|UniProtKB=W5M3R1 W5M3R1 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012360.1|UniProtKB=W5N3K7 W5N3K7 PTHR10353:SF291 GLYCOSYL HYDROLASE CYTOSOLIC BETA-GLUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017044.1|UniProtKB=W5NKA4 W5NKA4 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001079.1|UniProtKB=W5LYK8 W5LYK8 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006823.1|UniProtKB=W5MIN6 W5MIN6 C16orf89 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 LEPOC|Ensembl=ENSLOCG00000010605.1|UniProtKB=W5MX82 W5MX82 PTHR34533:SF3 TRANSMEMBRANE PROTEIN CCDC163 BICD FAMILY-LIKE CARGO ADAPTER 2 LEPOC|Ensembl=ENSLOCG00000001698.1|UniProtKB=W5M0Q5 W5M0Q5 PTHR11188:SF49 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002441.1|UniProtKB=W5M3A6 W5M3A6 TUBB4B PTHR11588:SF247 TUBULIN TUBULIN BETA-4B CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 LEPOC|Ensembl=ENSLOCG00000009219.1|UniProtKB=W5MS89 W5MS89 PTHR13238:SF0 PROTEIN C21ORF59 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298 LEPOC|Ensembl=ENSLOCG00000000912.1|UniProtKB=W5LY10 W5LY10 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-4 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002223.1|UniProtKB=W5M2H9 W5M2H9 PTHR22710:SF2 X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1 X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010910.1|UniProtKB=W5MYC2 W5MYC2 PTHR12596:SF1 EXPORTIN 4,7-RELATED EXPORTIN-4 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007235.1|UniProtKB=W5MK48 W5MK48 PTHR12391:SF0 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 LEPOC|Ensembl=ENSLOCG00000004961.1|UniProtKB=W5MC56 W5MC56 RAB17 PTHR24073:SF912 DRAB5-RELATED RAS-RELATED PROTEIN RAB-17 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000008737.1|UniProtKB=W5MQH8 W5MQH8 PTHR12894:SF29 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 HOMOLOG vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagy#GO:0006914;organelle fusion#GO:0048284;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016302.1|UniProtKB=W5NHL0 W5NHL0 PTHR11534:SF3 MYOGENIC FACTOR MYOGENIC FACTOR 5 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 muscle organ development#GO:0007517;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017894.1|UniProtKB=W5NMY8 W5NMY8 REP15 PTHR36682:SF1 RAB15 EFFECTOR PROTEIN RAB15 EFFECTOR PROTEIN LEPOC|Ensembl=ENSLOCG00000005069.1|UniProtKB=W5MCJ3 W5MCJ3 PTHR11818:SF38 BETA/GAMMA CRYSTALLIN VERY LARGE A-KINASE ANCHOR PROTEIN structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015881.1|UniProtKB=W5NFZ7 W5NFZ7 PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001723.1|UniProtKB=W5M0T1 W5M0T1 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 3 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000002735.1|UniProtKB=W5M4A9 W5M4A9 GRIN3A PTHR18966:SF397 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3A transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated channel activity#GO:0022832;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 LEPOC|Ensembl=ENSLOCG00000011895.1|UniProtKB=W5N1X0 W5N1X0 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000013010.1|UniProtKB=W5N5W6 W5N5W6 PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound biosynthetic process#GO:0019438;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 CCKR signaling map#P06959>HDC#G06969;CCKR signaling map#P06959>HDC#G07262;Histamine synthesis#P04387>Histidine decarboxylase#P04493 LEPOC|Ensembl=ENSLOCG00000016435.1|UniProtKB=W5NI41 W5NI41 PLCB4 PTHR10336:SF36 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;release of sequestered calcium ion into cytosol#GO:0051209;regulation of localization#GO:0032879;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;signaling#GO:0023052;monoatomic cation transmembrane transport#GO:0098655;negative regulation of cellular process#GO:0048523 phospholipase#PC00186 Metabotropic glutamate receptor group I pathway#P00041>PLC#P01053;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PLC#P01068;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 LEPOC|Ensembl=ENSLOCG00000004760.1|UniProtKB=W5MBF9 W5MBF9 RGS3 PTHR46848:SF1 REGULATOR OF G-PROTEIN SIGNALING 3 REGULATOR OF G-PROTEIN SIGNALING 3 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000007154.1|UniProtKB=W5MJV0 W5MJV0 PTHR31909:SF3 CHROMOSOME 20 ORF85 FAMILY MEMBER SIMILAR TO PROTEIN C20ORF85 HOMOLOG LEPOC|Ensembl=ENSLOCG00000012514.1|UniProtKB=W5N463 W5N463 PTHR11801:SF2 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;defense response#GO:0006952;signaling#GO:0023052;receptor signaling pathway via JAK-STAT#GO:0007259;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to hormone#GO:0009725;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;regulation of macromolecule metabolic process#GO:0060255;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 PDGF signaling pathway#P00047>STAT#P01173;Angiogenesis#P00005>STAT3#P00217;CCKR signaling map#P06959>STAT3#P07165;JAK/STAT signaling pathway#P00038>STAT#P01027;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;Gonadotropin-releasing hormone receptor pathway#P06664>STAT3#P06795;Ras Pathway#P04393>Stat 1/3#P04566;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 LEPOC|Ensembl=ENSLOCG00000015686.1|UniProtKB=W5NFA2 W5NFA2 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003681.1|UniProtKB=W5M7K9 W5M7K9 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010812.1|UniProtKB=W5MXZ9 W5MXZ9 PTHR24161:SF121 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED M-PHASE PHOSPHOPROTEIN 8 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010902.1|UniProtKB=W5MYB6 W5MYB6 PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010894.1|UniProtKB=W5MY95 W5MY95 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008121.1|UniProtKB=W5MNB2 W5MNB2 RASA2 PTHR10194:SF21 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 2 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 LEPOC|Ensembl=ENSLOCG00000007217.1|UniProtKB=W5MK29 W5MK29 PTHR11475:SF63 OXIDASE/PEROXIDASE EOSINOPHIL PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005239.1|UniProtKB=W5MD49 W5MD49 PTHR10829:SF15 CORTACTIN AND DREBRIN SRC SUBSTRATE CORTACTIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;cell migration#GO:0016477;regulation of protein polymerization#GO:0032271 supramolecular complex#GO:0099080;cortical cytoskeleton#GO:0030863;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000010040.1|UniProtKB=W5MV72 W5MV72 PTHR39063:SF1 ORAL-FACIAL-DIGITAL SYNDROME 1 PROTEIN HOMOLOG OFD1 CENTRIOLE AND CENTRIOLAR SATELLITE PROTEIN left/right pattern formation#GO:0060972;multicellular organism development#GO:0007275;transport#GO:0006810;regionalization#GO:0003002;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cellular process#GO:0009987;cilium movement#GO:0003341;localization#GO:0051179;epithelial cilium movement involved in extracellular fluid movement#GO:0003351;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013863.1|UniProtKB=W5N8Z6 W5N8Z6 PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase II activity#GO:0001055 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000007592.1|UniProtKB=W5MLG5 W5MLG5 PTHR16308:SF18 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2-LIKE cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015865.1|UniProtKB=W5NFX3 W5NFX3 PTHR10901:SF12 TROPOMODULIN LEIOMODIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000018007.1|UniProtKB=W5NN99 W5NN99 PTHR24133:SF14 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006546.1|UniProtKB=W5MHQ3 W5MHQ3 PTHR11601:SF34 CYSTEINE DESULFURYLASE FAMILY MEMBER CYSTEINE DESULFURASE lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001948.1|UniProtKB=W5M1J9 W5M1J9 PRKAB2 PTHR10343:SF92 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000012719.1|UniProtKB=W5N4U0 W5N4U0 PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002281.1|UniProtKB=W5M2R5 W5M2R5 PTHR32379:SF1 GUANIDINOACETATE N-METHYLTRANSFERASE GUANIDINOACETATE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012103.1|UniProtKB=W5N2N5 W5N2N5 PTHR43655:SF9 ATP-DEPENDENT PROTEASE AFG3-LIKE PROTEIN 2 mitochondrial protein processing#GO:0034982;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;peptidase complex#GO:1905368;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013754.1|UniProtKB=W5N8N5 W5N8N5 PTHR22625:SF35 PLEXIN PLEXIN-A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>PlexinA1#P00334 LEPOC|Ensembl=ENSLOCG00000013786.1|UniProtKB=W5N8P1 W5N8P1 PTHR10676:SF359 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341 axoneme#GO:0005930;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012688.1|UniProtKB=W5N4Q1 W5N4Q1 PTHR12011:SF474 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G11-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006706.1|UniProtKB=W5MI94 W5MI94 PTHR16291:SF0 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008044.1|UniProtKB=W5MN09 W5MN09 ZP2 PTHR23343:SF4 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cell activation#GO:0001775;regulation of biological process#GO:0050789;cell recognition#GO:0008037;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000002191.1|UniProtKB=W5M2E4 W5M2E4 PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004906.1|UniProtKB=W5MBZ5 W5MBZ5 PTHR10285:SF68 URIDINE KINASE URIDINE-CYTIDINE KINASE-LIKE 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149 LEPOC|Ensembl=ENSLOCG00000001883.1|UniProtKB=W5M1C2 W5M1C2 PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016467.1|UniProtKB=W5NI86 W5NI86 PTHR47028:SF1 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 neuron projection guidance#GO:0097485;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;kidney development#GO:0001822;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;axonogenesis#GO:0007409;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;regulation of body fluid levels#GO:0050878;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;circulatory system process#GO:0003013;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;negative regulation of Wnt signaling pathway#GO:0030178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;blood circulation#GO:0008015;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;epithelium development#GO:0060429;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of system process#GO:0044057;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;regulation of systemic arterial blood pressure#GO:0003073;cell morphogenesis#GO:0000902;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of blood pressure#GO:0008217;regulation of Wnt signaling pathway#GO:0030111;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of canonical Wnt signaling pathway#GO:0090090;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001266.1|UniProtKB=W5LZ78 W5LZ78 PTHR24329:SF576 HOMEOBOX PROTEIN ARISTALESS RETINAL HOMEOBOX PROTEIN RX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003583.1|UniProtKB=W5M791 W5M791 PTHR13602:SF2 UPF0488 PROTEIN C8ORF33 UPF0488 PROTEIN C8ORF33 LEPOC|Ensembl=ENSLOCG00000004081.1|UniProtKB=W5M948 W5M948 PTHR22957:SF187 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000011545.1|UniProtKB=W5N0M9 W5N0M9 FGD2 PTHR12673:SF82 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;filopodium assembly#GO:0046847;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006496.1|UniProtKB=W5MHJ4 W5MHJ4 PTHR42985:SF15 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 2 symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001850.1|UniProtKB=W5M187 W5M187 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cell projection organization#GO:0030030;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001865.1|UniProtKB=W5M1A2 W5M1A2 PTHR12753:SF2 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 2 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001750.1|UniProtKB=W5M0W3 W5M0W3 PTHR48011:SF4 CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000007384.1|UniProtKB=W5MKQ0 W5MKQ0 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO RNA-BINDING PROTEIN RO60 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009289.1|UniProtKB=W5MSG7 W5MSG7 PTHR14636:SF1 TPA-INDUCED TRANSMEMBRANE PROTEIN TPA-INDUCED TRANSMEMBRANE PROTEIN LEPOC|Ensembl=ENSLOCG00000000380.1|UniProtKB=W5LWA8 W5LWA8 PTHR45639:SF2 HSC70CB, ISOFORM G-RELATED HEAT SHOCK PROTEIN 105 KDA macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000005747.1|UniProtKB=W5MEY0 W5MEY0 PTHR12487:SF5 TEASHIRT-RELATED TEASHIRT HOMOLOG 3 nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016988.1|UniProtKB=W5NK39 W5NK39 PTHR34257:SF4 ADAPTER PROTEIN CIKS ADAPTER PROTEIN CIKS positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;immune response#GO:0006955;humoral immune response#GO:0006959;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011347.1|UniProtKB=W5MZY6 W5MZY6 PTHR19969:SF13 SH2-SH3 ADAPTOR PROTEIN-RELATED GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005805.1|UniProtKB=W5MF53 W5MF53 PTHR31488:SF4 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L3-RELATED mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004597.1|UniProtKB=W5MAU9 W5MAU9 OBI1 PTHR14609:SF1 RING FINGER PROTEIN 219 ORC UBIQUITIN LIGASE 1 LEPOC|Ensembl=ENSLOCG00000010975.1|UniProtKB=W5MYK3 W5MYK3 PTHR10366:SF364 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE_DELTA 5--4-ISOMERASE TYPE 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144 Androgen/estrogene/progesterone biosynthesis#P02727>3beta-Hydroxysteroid dehydrogenase#P02833 LEPOC|Ensembl=ENSLOCG00000008845.1|UniProtKB=W5MQX5 W5MQX5 DAB1 PTHR47695:SF4 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 1 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell motility#GO:0048870;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016027.1|UniProtKB=W5NGI3 W5NGI3 PTHR11309:SF22 FRIZZLED FRIZZLED-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>FRP#P00237;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000016264.1|UniProtKB=W5NHF1 W5NHF1 PTHR14002:SF60 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZP DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017232.1|UniProtKB=W5NL05 W5NL05 PTHR28676:SF2 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 2 protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;enzyme regulator activity#GO:0030234;signaling receptor binding#GO:0005102;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;protein binding#GO:0005515;protein kinase binding#GO:0019901 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000004947.1|UniProtKB=W5MC39 W5MC39 PTHR17206:SF1 PROLACTIN-RELEASING PEPTIDE PROLACTIN-RELEASING PEPTIDE neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to oxygen-containing compound#GO:1901700;response to peptide hormone#GO:0043434;behavior#GO:0007610;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to chemical#GO:0042221;response to peptide#GO:1901652;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000009396.1|UniProtKB=W5MSV2 W5MSV2 PTHR13372:SF2 GEMININ GEMININ COILED-COIL DOMAIN-CONTAINING PROTEIN 1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cell cycle#GO:0045786;regulation of DNA metabolic process#GO:0051052;negative regulation of metabolic process#GO:0009892;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005170.1|UniProtKB=W5MD76 W5MD76 PTHR13817:SF103 TITIN ROUNDABOUT GUIDANCE RECEPTOR 3 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015250.1|UniProtKB=W5NDQ7 W5NDQ7 PTHR12064:SF26 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM4 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016556.1|UniProtKB=W5NII9 W5NII9 PTHR46878:SF1 FORKHEAD BOX PROTEIN M1 FORKHEAD BOX PROTEIN M1 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000012092.1|UniProtKB=W5N2M0 W5N2M0 PTHR28495:SF1 HYPOTHETICAL PROTEIN LOC100359752 GENE, 17266-RELATED LEPOC|Ensembl=ENSLOCG00000016359.1|UniProtKB=W5NHU1 W5NHU1 PTHR22852:SF0 LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN DENTICLELESS PROTEIN HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003615.1|UniProtKB=W5M7C9 W5M7C9 PTHR24070:SF221 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;small GTPase-mediated signal transduction#GO:0007264;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;negative regulation of cell migration#GO:0030336 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906 LEPOC|Ensembl=ENSLOCG00000013001.1|UniProtKB=W5N5V4 W5N5V4 LIAS PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 LEPOC|Ensembl=ENSLOCG00000004045.1|UniProtKB=W5M934 W5M934 KMT2A PTHR45838:SF2 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2A N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;histone H3K4 methyltransferase activity#GO:0042800;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000013443.1|UniProtKB=W5N7G7 W5N7G7 PTHR45659:SF9 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009088.1|UniProtKB=W5MRR8 W5MRR8 PTHR24173:SF27 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005155.1|UniProtKB=W5MCV4 W5MCV4 PTHR12308:SF13 ANOCTAMIN ANOCTAMIN-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005443.1|UniProtKB=W5MDV9 W5MDV9 PTHR24356:SF158 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C BETA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>PKCbeta#P07177;EGF receptor signaling pathway#P00018>PKC#P00565;Metabotropic glutamate receptor group I pathway#P00041>PKC#P01055;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;B cell activation#P00010>PKC#P00373;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 LEPOC|Ensembl=ENSLOCG00000011703.1|UniProtKB=W5N176 W5N176 PTHR13378:SF1 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018049.1|UniProtKB=W5NNE1 W5NNE1 CYSLTR2 PTHR24231:SF48 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006807.1|UniProtKB=W5MIL5 W5MIL5 PTHR24103:SF654 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN_ISG15 LIGASE TRIM25 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005248.1|UniProtKB=W5MD65 W5MD65 PTHR11675:SF123 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016581.1|UniProtKB=W5NIM8 W5NIM8 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;dicarboxylic acid metabolic process#GO:0043648;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 LEPOC|Ensembl=ENSLOCG00000011104.1|UniProtKB=W5MZ38 W5MZ38 PTHR24390:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 366 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;organic cyclic compound binding#GO:0097159;transcription corepressor activity#GO:0003714;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004506.1|UniProtKB=W5MAI5 W5MAI5 PTHR45818:SF4 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;cell motility#GO:0048870;cell migration#GO:0016477;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 LEPOC|Ensembl=ENSLOCG00000007347.1|UniProtKB=W5MKL2 W5MKL2 SHROOM2 PTHR15012:SF8 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000004939.1|UniProtKB=W5MC32 W5MC32 PTHR12377:SF0 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;gene expression#GO:0010467;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000010195.1|UniProtKB=W5MVS1 W5MVS1 PTHR24412:SF433 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002436.1|UniProtKB=W5M3B4 W5M3B4 RAB31 PTHR24073:SF588 DRAB5-RELATED RAS-RELATED PROTEIN RAB-31 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005078.1|UniProtKB=W5MCK7 W5MCK7 PTHR28532:SF1 GEO13458P1 ORAL CANCER OVEREXPRESSED 1 LEPOC|Ensembl=ENSLOCG00000001946.1|UniProtKB=W5M1K0 W5M1K0 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009413.1|UniProtKB=W5MSY2 W5MSY2 PTHR18945:SF883 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A-LIKE ISOFORM X1 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014944.1|UniProtKB=W5NCP3 W5NCP3 PTHR45618:SF20 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED BRAIN MITOCHONDRIAL CARRIER PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014222.1|UniProtKB=W5NA56 W5NA56 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002750.1|UniProtKB=W5M4D2 W5M4D2 THAP3 PTHR47120:SF1 THAP DOMAIN-CONTAINING PROTEIN 3 THAP DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000006109.1|UniProtKB=W5MG73 W5MG73 TMEM52 PTHR33955:SF2 TRANSMEMBRANE PROTEIN 52 TRANSMEMBRANE PROTEIN 52 LEPOC|Ensembl=ENSLOCG00000013954.1|UniProtKB=W5N992 W5N992 PPARG PTHR24082:SF488 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of inflammatory response#GO:0050728;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;negative regulation of defense response#GO:0031348;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;negative regulation of nitrogen compound metabolic process#GO:0051172;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of response to stress#GO:0080134;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;positive regulation of RNA metabolic process#GO:0051254;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CCKR signaling map#P06959>PPARgamma#P07060;Gonadotropin-releasing hormone receptor pathway#P06664>PPARgamma#P06721;Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744 LEPOC|Ensembl=ENSLOCG00000004836.1|UniProtKB=W5MBQ4 W5MBQ4 CTU2 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013022.1|UniProtKB=W5N5Y1 W5N5Y1 PTHR24193:SF76 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011022.1|UniProtKB=W5MYR8 W5MYR8 PTHR13137:SF6 DC11 ACN9 HOMOLOG SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;cellular component assembly#GO:0022607;dicarboxylic acid metabolic process#GO:0043648;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;protein-containing complex assembly#GO:0065003;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex II assembly#GO:0034553;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007274.1|UniProtKB=W5MKB8 W5MKB8 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009792.1|UniProtKB=W5MUB1 W5MUB1 PTHR14619:SF1 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 LEPOC|Ensembl=ENSLOCG00000010348.1|UniProtKB=W5MWD1 W5MWD1 PTHR11243:SF15 GROWTH FACTOR RECEPTOR-BOUND PROTEIN RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004916.1|UniProtKB=W5MC20 W5MC20 PTHR10064:SF2 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006076.1|UniProtKB=W5MG25 W5MG25 PTHR14758:SF4 AGAP005440-PA PROTEIN FAM110A LEPOC|Ensembl=ENSLOCG00000002394.1|UniProtKB=W5M350 W5M350 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 LEPOC|Ensembl=ENSLOCG00000005520.1|UniProtKB=W5ME58 W5ME58 PTHR23511:SF6 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2C synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000017119.1|UniProtKB=W5NKJ5 W5NKJ5 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000007720.1|UniProtKB=W5MLY3 W5MLY3 PTHR46256:SF4 AGAP011099-PA MYOSIN-IIIA microfilament motor activity#GO:0000146;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;cytoskeletal motor activity#GO:0003774;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of plasma membrane bounded cell projection assembly#GO:0120032;macromolecule modification#GO:0043412;sensory perception of sound#GO:0007605;system process#GO:0003008;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;phosphorylation#GO:0016310;positive regulation of cellular component biogenesis#GO:0044089;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nervous system process#GO:0050877;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;sensory perception of mechanical stimulus#GO:0050954;regulation of filopodium assembly#GO:0051489;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;peptidyl-serine modification#GO:0018209;multicellular organismal process#GO:0032501;sensory perception#GO:0007600 stereocilium#GO:0032420;stereocilium bundle#GO:0032421;cluster of actin-based cell projections#GO:0098862;filopodium#GO:0030175;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;photoreceptor inner segment#GO:0001917;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000009917.1|UniProtKB=W5MUR8 W5MUR8 PTHR15545:SF5 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 E3 UBIQUITIN-PROTEIN LIGASE PDZRN3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;neuromuscular junction development#GO:0007528;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;nitrogen compound metabolic process#GO:0006807;cell junction organization#GO:0034330;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000011078.1|UniProtKB=W5MZ16 W5MZ16 PTHR24416:SF47 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;osteoclast differentiation#GO:0030316;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;regulation of cell migration#GO:0030334;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of cell motility#GO:2000147;hemopoiesis#GO:0030097;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cell migration#GO:0030335;positive regulation of phosphate metabolic process#GO:0045937;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002064.1|UniProtKB=W5M1Z2 W5M1Z2 LAMC1 PTHR10574:SF270 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000008810.1|UniProtKB=W5MQR4 W5MQR4 C8A PTHR45742:SF1 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 ALPHA CHAIN activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000017850.1|UniProtKB=W5NMU4 W5NMU4 PTHR10903:SF180 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7-LIKE small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016332.1|UniProtKB=W5NHQ2 W5NHQ2 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004339.1|UniProtKB=W5M9Y3 W5M9Y3 PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013546.1|UniProtKB=W5N7U6 W5N7U6 PTHR18945:SF59 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT EPSILON monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000007560.1|UniProtKB=W5MLB3 W5MLB3 PTHR11576:SF3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 SI:CH211-14A17.6-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000007580.1|UniProtKB=W5MLF9 W5MLF9 PTHR10293:SF73 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012121.1|UniProtKB=W5N2Q4 W5N2Q4 PTHR48024:SF56 GEO13361P1-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0 LEPOC|Ensembl=ENSLOCG00000010620.1|UniProtKB=W5MXA0 W5MXA0 PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007651.1|UniProtKB=W5MLM2 W5MLM2 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000000965.1|UniProtKB=W5LY76 W5LY76 PTHR11827:SF97 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SLC12A10.3 SOLUTE CARRIER FAMILY 12 (SODIUM_POTASSIUM_CHLORIDE TRANSPORTERS), MEMBER 10, TANDEM DUPLICATE 3 ISOFORM X1-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;sodium ion homeostasis#GO:0055078;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;apical part of cell#GO:0045177 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008734.1|UniProtKB=W5MQG9 W5MQG9 PTHR13546:SF14 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85C cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000009469.1|UniProtKB=W5MT64 W5MT64 PTHR45850:SF4 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-6 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001430.1|UniProtKB=W5LZS7 W5LZS7 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR COMPLEX PROTEIN WDR59 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001927.1|UniProtKB=W5M1I9 W5M1I9 MPRIP PTHR17271:SF9 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014714.1|UniProtKB=W5NBV9 W5NBV9 PTHR24240:SF17 OPSIN MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009575.1|UniProtKB=W5MTN8 W5MTN8 PTHR24035:SF138 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 6 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002030.1|UniProtKB=W5M1U1 W5M1U1 PTHR24103:SF695 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-18P12.4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011690.1|UniProtKB=W5N153 W5N153 PTHR24228:SF49 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1A-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008159.1|UniProtKB=W5MNE4 W5MNE4 PTHR20934:SF0 TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000004202.1|UniProtKB=W5M9G1 W5M9G1 PTHR23003:SF45 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 4 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010209.1|UniProtKB=W5MVT9 W5MVT9 PTHR10231:SF36 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-N-ACETYLGLUCOSAMINE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004243.1|UniProtKB=W5M9L4 W5M9L4 PTHR24100:SF151 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003717.1|UniProtKB=W5M7R9 W5M7R9 PTHR46054:SF1 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;RNA localization#GO:0006403;axo-dendritic transport#GO:0008088;cell differentiation#GO:0030154;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;reproductive process#GO:0022414;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;protein localization to synapse#GO:0035418;multicellular organism reproduction#GO:0032504;cellular process#GO:0009987;transport along microtubule#GO:0010970;protein localization#GO:0008104;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;localization#GO:0051179;microtubule-based transport#GO:0099111;reproduction#GO:0000003;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;sexual reproduction#GO:0019953;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;cell body#GO:0044297;neuron projection#GO:0043005;cytoplasmic stress granule#GO:0010494;cell projection#GO:0042995;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006976.1|UniProtKB=W5MJ83 W5MJ83 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010780.1|UniProtKB=W5MXV0 W5MXV0 PTHR10331:SF27 T COMPLEX PROTEIN 10 CENTROMERE PROTEIN J cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;centriole assembly#GO:0098534;cell projection organization#GO:0030030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;centriole elongation#GO:0061511;plasma membrane bounded cell projection assembly#GO:0120031;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000013068.1|UniProtKB=W5N636 W5N636 PTHR16717:SF7 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8A, MITOCHONDRIAL-LIKE membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004954.1|UniProtKB=W5MC45 W5MC45 PTHR13232:SF12 NAD(P)H-HYDRATE EPIMERASE YJEF N-TERMINAL DOMAIN-CONTAINING PROTEIN 3 isomerase activity#GO:0016853;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015558.1|UniProtKB=W5NEU2 W5NEU2 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 69 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012898.1|UniProtKB=W5N5G7 W5N5G7 PTHR17085:SF3 NUCLEAR RECEPTOR COACTIVATOR 4 NUCLEAR RECEPTOR COACTIVATOR 4 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to chemical#GO:0042221 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015813.1|UniProtKB=W5NFQ9 W5NFQ9 PTHR11380:SF16 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001121.1|UniProtKB=W5LYQ4 W5LYQ4 PTHR46841:SF7 OX-2 MEMBRANE GLYCOPROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of response to stress#GO:0080134;negative regulation of inflammatory response#GO:0050728;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;negative regulation of defense response#GO:0031348;cellular process#GO:0009987 cell surface#GO:0009986;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000001403.1|UniProtKB=W5LZN9 W5LZN9 PTHR11538:SF26 PHENYLALANYL-TRNA SYNTHETASE FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;peptide metabolic process#GO:0006518;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;macromolecule methylation#GO:0043414;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000001018.1|UniProtKB=W5LYH7 W5LYH7 PTHR23103:SF14 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 2 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;central nervous system development#GO:0007417;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013559.1|UniProtKB=W5N7W4 W5N7W4 PTHR19384:SF84 NITRIC OXIDE SYNTHASE-RELATED METHIONINE SYNTHASE REDUCTASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on metal ions#GO:0016722;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017628.1|UniProtKB=W5NM74 W5NM74 PTHR11462:SF7 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUND cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838;Gonadotropin-releasing hormone receptor pathway#P06664>Jund#P06764 LEPOC|Ensembl=ENSLOCG00000016539.1|UniProtKB=W5NIG6 W5NIG6 LIN28B PTHR46109:SF3 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;pre-miRNA processing#GO:0031054;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014002.1|UniProtKB=W5N9F4 W5N9F4 PTHR10545:SF66 DIAMINE N-ACETYLTRANSFERASE DIAMINE N-ACETYLTRANSFERASE 2-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000017780.1|UniProtKB=W5NMM5 W5NMM5 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000011252.1|UniProtKB=W5MZL2 W5MZL2 PTHR23147:SF22 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002608.1|UniProtKB=W5M3X3 W5M3X3 PTHR11711:SF147 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000008977.1|UniProtKB=W5MRD2 W5MRD2 FOXN3 PTHR13962:SF20 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000008574.1|UniProtKB=W5MPX2 W5MPX2 MYO18B PTHR45615:SF8 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIB microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000016569.1|UniProtKB=W5NIK5 W5NIK5 PTHR28675:SF1 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012038.1|UniProtKB=W5N2F4 W5N2F4 PTHR15146:SF1 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137C regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000563.1|UniProtKB=W5LWW8 W5LWW8 PTHR46497:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000004.1|UniProtKB=W5LV47 W5LV47 PTHR48094:SF18 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 1 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012286.1|UniProtKB=W5N3B8 W5N3B8 PTHR12563:SF16 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;fatty acid metabolic process#GO:0006631;glycerolipid metabolic process#GO:0046486;glycerol-3-phosphate metabolic process#GO:0006072;triglyceride biosynthetic process#GO:0019432;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005229.1|UniProtKB=W5MD37 W5MD37 PTHR21004:SF0 SERINE PROTEASE-RELATED PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016288.1|UniProtKB=W5NHI8 W5NHI8 PPP1R12A PTHR24179:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12A phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 supramolecular complex#GO:0099080;Z disc#GO:0030018;A band#GO:0031672;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;myofibril#GO:0030016;I band#GO:0031674 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000004197.1|UniProtKB=W5M9F8 W5M9F8 SLC10A6 PTHR10361:SF55 SODIUM-BILE ACID COTRANSPORTER SODIUM-DEPENDENT ORGANIC ANION TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006596.1|UniProtKB=W5MHW3 W5MHW3 PTHR23344:SF13 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003267.1|UniProtKB=W5M650 W5M650 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-1-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000018088.1|UniProtKB=W5NNI0 W5NNI0 PTHR28564:SF1 STANNIN STANNIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000920.1|UniProtKB=W5LY18 W5LY18 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014025.1|UniProtKB=W5N9I5 W5N9I5 PTHR16092:SF14 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 ISOFORM X1 phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000016285.1|UniProtKB=W5NHJ0 W5NHJ0 PTHR48092:SF16 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007819.1|UniProtKB=W5MM82 W5MM82 PTHR24183:SF1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of programmed cell death#GO:0043067;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018321.1|UniProtKB=W5NP63 W5NP63 PTHR10489:SF686 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 5 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000014914.1|UniProtKB=W5NCL1 W5NCL1 PTHR21444:SF16 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 RECEPTOR FOR RETINOL UPTAKE STRA6 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;transmembrane transport#GO:0055085;transport#GO:0006810;vitamin transport#GO:0051180;lipid localization#GO:0010876;cellular process#GO:0009987;import into cell#GO:0098657;lipid transport#GO:0006869 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014718.1|UniProtKB=W5NBW0 W5NBW0 PTHR11202:SF12 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER VASODILATOR-STIMULATED PHOSPHOPROTEIN protein binding#GO:0005515;SH3 domain binding#GO:0017124;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;tube morphogenesis#GO:0035239;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of organelle organization#GO:0033043;tube development#GO:0035295;cellular component organization#GO:0016043;positive regulation of cellular process#GO:0048522;chordate embryonic development#GO:0043009;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;embryo development#GO:0009790;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;positive regulation of organelle organization#GO:0010638;epithelium development#GO:0060429;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;axon guidance#GO:0007411;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036;embryonic morphogenesis#GO:0048598 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516;Integrin signalling pathway#P00034>VASP#P00934;Axon guidance mediated by netrin#P00009>Ena#P00361 LEPOC|Ensembl=ENSLOCG00000003884.1|UniProtKB=W5M8D7 W5M8D7 PTHR21646:SF44 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 31 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012179.1|UniProtKB=W5N2X1 W5N2X1 C9orf72 PTHR31855:SF2 GUANINE NUCLEOTIDE EXCHANGE C9ORF72 GUANINE NUCLEOTIDE EXCHANGE FACTOR C9ORF72 LEPOC|Ensembl=ENSLOCG00000005351.1|UniProtKB=W5MDI9 W5MDI9 PTHR12027:SF94 WNT RELATED PROTEIN WNT-8B molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000017571.1|UniProtKB=W5NM17 W5NM17 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017989.1|UniProtKB=W5NN81 W5NN81 PTHR21426:SF12 EXOCYST COMPLEX COMPONENT 8 EXOCYST COMPLEX COMPONENT 8 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015552.1|UniProtKB=W5NET5 W5NET5 PTHR24240:SF16 OPSIN SHORT-WAVE-SENSITIVE OPSIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008152.1|UniProtKB=W5MND9 W5MND9 PTHR43313:SF52 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C DEHYDROGENASE_REDUCTASE (SDR FAMILY) MEMBER 9 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004185.1|UniProtKB=W5M9D5 W5M9D5 PTHR22913:SF4 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosaminoglycan metabolic process#GO:0030203;cellular component assembly#GO:0022607;carbohydrate biosynthetic process#GO:0016051;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;polysaccharide metabolic process#GO:0005976;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014056.1|UniProtKB=W5N9L5 W5N9L5 PTHR11753:SF14 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-1A localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000017724.1|UniProtKB=W5NMG9 W5NMG9 PTHR46617:SF5 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015223.1|UniProtKB=W5NDM6 W5NDM6 PTHR13484:SF8 FIP1-LIKE 1 PROTEIN PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011291.1|UniProtKB=W5MZS2 W5MZS2 PTHR12650:SF30 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI 40S RIBOSOMAL PROTEIN S30-RELATED cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008295.1|UniProtKB=W5MNW4 W5MNW4 CSRNP3 PTHR13580:SF13 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 3 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003349.1|UniProtKB=W5M6E7 W5M6E7 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010840.1|UniProtKB=W5MY28 W5MY28 PTHR12300:SF33 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996 supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;microtubule#GO:0005874;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009890.1|UniProtKB=W5MUM9 W5MUM9 PTHR10903:SF186 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012565.1|UniProtKB=W5N4B3 W5N4B3 PTHR46792:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 COILED-COIL DOMAIN-CONTAINING 80-LIKE 2 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;positive regulation of cell-substrate adhesion#GO:0010811;external encapsulating structure organization#GO:0045229;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular component organization#GO:0016043;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;extracellular matrix organization#GO:0030198;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cellular process#GO:0048522 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;basement membrane#GO:0005604 LEPOC|Ensembl=ENSLOCG00000012199.1|UniProtKB=W5N2Z4 W5N2Z4 PTHR10159:SF111 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;endoderm formation#GO:0001706;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;regulation of cellular process#GO:0050794;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;embryonic morphogenesis#GO:0048598 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000013613.1|UniProtKB=W5N826 W5N826 PTHR19961:SF32 FIMBRIN/PLASTIN PLASTIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011733.1|UniProtKB=W5N1B4 W5N1B4 PTHR24411:SF8 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000007601.1|UniProtKB=W5MLG8 W5MLG8 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000014289.1|UniProtKB=W5NAD4 W5NAD4 PTHR24068:SF33 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q 2 ISOFORM 1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009083.1|UniProtKB=W5MRT1 W5MRT1 PTHR18966:SF36 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 1 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;sodium channel activity#GO:0005272;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA1#P01004;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054 LEPOC|Ensembl=ENSLOCG00000011007.1|UniProtKB=W5MYP5 W5MYP5 PTHR14093:SF17 HLA CLASS II GAMMA CHAIN HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;MHC protein binding#GO:0042287;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;antigen processing and presentation#GO:0019882;positive regulation of protein modification process#GO:0031401;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of immune response#GO:0050778;regulation of cellular response to stress#GO:0080135;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of cytokine production#GO:0001819;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;leukocyte activation#GO:0045321;regulation of kinase activity#GO:0043549;lymphocyte activation involved in immune response#GO:0002285;regulation of multicellular organismal process#GO:0051239;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;T cell activation involved in immune response#GO:0002286;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cytokine-mediated signaling pathway#GO:0001961;regulation of immune system process#GO:0002682;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;immune effector process#GO:0002252;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cytokine production#GO:0001817;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;lymphocyte activation#GO:0046649;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;regulation of immune effector process#GO:0002697;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;T cell activation#GO:0042110;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 cytoplasm#GO:0005737;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000000535.1|UniProtKB=W5LWT4 W5LWT4 MRPS12 PTHR11652:SF71 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000935.1|UniProtKB=W5LY79 W5LY79 PTHR14049:SF5 LEPRECAN 1 PROLYL 3-HYDROXYLASE 1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000014616.1|UniProtKB=W5NBH5 W5NBH5 PTHR24366:SF99 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000013825.1|UniProtKB=W5N8T9 W5N8T9 PTHR28594:SF1 ATR-INTERACTING PROTEIN ATR-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000007642.1|UniProtKB=W5MLL2 W5MLL2 PTHR46805:SF3 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1-B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001918.1|UniProtKB=W5M1G5 W5M1G5 PTHR12473:SF18 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4B hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000007365.1|UniProtKB=W5MKN6 W5MKN6 PTHR13944:SF20 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of cell differentiation#GO:0045597;developmental process#GO:0032502;regulation of signaling#GO:0023051;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of neuron differentiation#GO:0045664;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ruffle membrane#GO:0032587;ruffle#GO:0001726;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017035.1|UniProtKB=W5NK96 W5NK96 PTHR12072:SF4 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013660.1|UniProtKB=W5N885 W5N885 APOH PTHR19325:SF549 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING BETA-2-GLYCOPROTEIN 1 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000017233.1|UniProtKB=W5NL06 W5NL06 PTHR22593:SF2 TRANSMEMBRANE PROTEIN 18 TRANSMEMBRANE PROTEIN 18 envelope#GO:0031975;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004790.1|UniProtKB=W5MBK5 W5MBK5 PTHR12280:SF20 PANTOTHENATE KINASE 4'-PHOSPHOPANTETHEINE PHOSPHATASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000001194.1|UniProtKB=W5LYY9 W5LYY9 PTHR14677:SF20 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016712.1|UniProtKB=W5NJ44 W5NJ44 PTHR15627:SF14 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 PROTEIN YIPF3 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000405.1|UniProtKB=W5LWD4 W5LWD4 PTHR24208:SF118 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013004.1|UniProtKB=W5N5V5 W5N5V5 PTHR41693:SF2 HEME-BINDING PROTEIN 1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 LEPOC|Ensembl=ENSLOCG00000007916.1|UniProtKB=W5MMM3 W5MMM3 PTHR18947:SF37 HOOK PROTEINS PROTEIN HOOK HOMOLOG 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000109.1|UniProtKB=W5LVG1 W5LVG1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012602.1|UniProtKB=W5N4F9 W5N4F9 PTHR23116:SF29 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED PDZ DOMAIN-CONTAINING PROTEIN 7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000009039.1|UniProtKB=W5MRK5 W5MRK5 PTHR31109:SF2 PROTEIN FAM207A RIBOSOME BIOGENESIS PROTEIN SLX9 HOMOLOG LEPOC|Ensembl=ENSLOCG00000002035.1|UniProtKB=W5M1U7 W5M1U7 PTHR31129:SF2 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONE ALPHA-2 protein binding#GO:0005515;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000004253.1|UniProtKB=W5M9M8 W5M9M8 PTHR24339:SF29 HOMEOBOX PROTEIN EMX-RELATED GS HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010872.1|UniProtKB=W5MY60 W5MY60 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005877.1|UniProtKB=W5MFE4 W5MFE4 PTHR46120:SF1 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 HCY-BINDING DOMAIN-CONTAINING PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006888.1|UniProtKB=W5MIX0 W5MIX0 PTHR47980:SF2 LD44762P RAS-RELATED PROTEIN RAB-40C GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012744.1|UniProtKB=W5N4W9 W5N4W9 PTHR15240:SF4 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 4 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;plasma membrane raft#GO:0044853;caveola#GO:0005901;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001731.1|UniProtKB=W5M0U7 W5M0U7 PTHR24412:SF396 KELCH PROTEIN INFLUENZA VIRUS NS1A-BINDING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005698.1|UniProtKB=W5MER8 W5MER8 PTHR24253:SF172 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002340.1|UniProtKB=W5M303 W5M303 PTHR23319:SF3 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-B cholesterol transfer activity#GO:0120020;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;cholesterol binding#GO:0015485 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;intracellular sterol transport#GO:0032366;establishment of localization in cell#GO:0051649;lipid localization#GO:0010876;intracellular transport#GO:0046907;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular lipid transport#GO:0032365 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002496.1|UniProtKB=W5M3J0 W5M3J0 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006607.1|UniProtKB=W5MHX4 W5MHX4 PTHR24356:SF246 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 LEPOC|Ensembl=ENSLOCG00000017756.1|UniProtKB=W5NMK1 W5NMK1 PTHR24229:SF111 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular response to steroid hormone stimulus#GO:0071383;regulation of signaling#GO:0023051;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of peptide secretion#GO:0002791;cellular response to hormone stimulus#GO:0032870;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;neuropeptide signaling pathway#GO:0007218;regulation of hormone secretion#GO:0046883;cellular response to organic cyclic compound#GO:0071407;regulation of protein transport#GO:0051223;signaling#GO:0023052;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;regulation of hormone levels#GO:0010817;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of establishment of protein localization#GO:0070201;response to steroid hormone#GO:0048545;regulation of peptide transport#GO:0090087 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012279.1|UniProtKB=W5N3A4 W5N3A4 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 GTP-BINDING PROTEIN 4 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 LEPOC|Ensembl=ENSLOCG00000010279.1|UniProtKB=W5MW30 W5MW30 PTHR44281:SF5 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;centriole assembly#GO:0098534;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015162.1|UniProtKB=W5NDF0 W5NDF0 PTHR12832:SF17 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008801.1|UniProtKB=W5MQQ8 W5MQQ8 PTHR46099:SF2 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN-1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;system process#GO:0003008;pigmentation#GO:0043473;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;developmental pigmentation#GO:0048066;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>ET-RA/B#P00580 LEPOC|Ensembl=ENSLOCG00000003248.1|UniProtKB=W5M630 W5M630 PTHR22894:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF170 LEPOC|Ensembl=ENSLOCG00000015218.1|UniProtKB=W5NDL9 W5NDL9 PTHR24416:SF552 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;positive regulation of cellular metabolic process#GO:0031325;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of angiogenesis#GO:0045765;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell motility#GO:0048870;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 LEPOC|Ensembl=ENSLOCG00000004703.1|UniProtKB=W5MB79 W5MB79 PTHR22948:SF65 TUDOR DOMAIN CONTAINING PROTEIN A-KINASE ANCHORING PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004993.1|UniProtKB=W5MCA6 W5MCA6 PTHR13024:SF2 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN-LIKE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;basolateral plasma membrane#GO:0016323;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;basal plasma membrane#GO:0009925;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;basal part of cell#GO:0045178;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013331.1|UniProtKB=W5N730 W5N730 PTHR45905:SF3 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007510.1|UniProtKB=W5ML52 W5ML52 PTHR45710:SF31 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013352.1|UniProtKB=W5N747 W5N747 CXCL8 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A PLATELET BASIC PROTEIN cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016769.1|UniProtKB=W5NJC7 W5NJC7 PTHR11468:SF29 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, BRAIN FORM transferase activity#GO:0016740;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 LEPOC|Ensembl=ENSLOCG00000000326.1|UniProtKB=W5LW52 W5LW52 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000016263.1|UniProtKB=W5NHF2 W5NHF2 PTHR16517:SF2 TUBBY-RELATED TUBBY-RELATED PROTEIN 4 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016190.1|UniProtKB=W5NH47 W5NH47 PTHR23204:SF10 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017757.1|UniProtKB=W5NMK2 W5NMK2 PTHR17068:SF5 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006565.1|UniProtKB=W5MHS2 W5MHS2 PTHR10466:SF2 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 2 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;hexose metabolic process#GO:0019318;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 LEPOC|Ensembl=ENSLOCG00000015982.1|UniProtKB=W5NGC0 W5NGC0 SEL1L2 PTHR11102:SF147 SEL-1-LIKE PROTEIN SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000710.1|UniProtKB=W5LXD4 W5LXD4 PTHR23306:SF17 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUSCEPTIBILITY GENE 101 PROTEIN protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003386.1|UniProtKB=W5M6K2 W5M6K2 PTHR46404:SF1 DNA POLYMERASE IOTA DNA POLYMERASE IOTA DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010773.1|UniProtKB=W5MXU7 W5MXU7 PTHR10606:SF48 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;sugar-phosphatase activity#GO:0050308;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002969.1|UniProtKB=W5M536 W5M536 PTHR23292:SF48 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR HOMOLOG-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003963.1|UniProtKB=W5M8M2 W5M8M2 PTHR11932:SF168 CULLIN CULLIN-3 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004250.1|UniProtKB=W5M9M5 W5M9M5 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000012035.1|UniProtKB=W5N2E3 W5N2E3 PTHR11866:SF8 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;positive regulation of cytosolic calcium ion concentration#GO:0007204;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000004482.1|UniProtKB=W5MAE5 W5MAE5 PTHR14334:SF1 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN ALPHA CHAIN immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;mononuclear cell differentiation#GO:1903131;developmental process#GO:0032502;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of immune response#GO:0050778;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;response to stimulus#GO:0050896;immune system process#GO:0002376;B cell differentiation#GO:0030183;lymphocyte differentiation#GO:0030098;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 B cell activation#P00010>Ig-alpha#P00399 LEPOC|Ensembl=ENSLOCG00000000871.1|UniProtKB=W5LY02 W5LY02 MYH6 PTHR45615:SF1 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;actin filament-based movement#GO:0030048;animal organ development#GO:0048513;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle contraction#GO:0060048;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;heart process#GO:0003015;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000009207.1|UniProtKB=W5MS79 W5MS79 PTHR23158:SF38 MELANOMA INHIBITORY ACTIVITY-RELATED MELANOMA INHIBITORY ACTIVITY PROTEIN 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010300.1|UniProtKB=W5MW56 W5MW56 CFAP69 PTHR14716:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009779.1|UniProtKB=W5MUA0 W5MUA0 PTHR24278:SF28 COAGULATION FACTOR COAGULATION FACTOR X extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 Blood coagulation#P00011>FX#P00430;Blood coagulation#P00011>FXa#P00445 LEPOC|Ensembl=ENSLOCG00000016306.1|UniProtKB=W5NHL8 W5NHL8 PTHR14168:SF4 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER EPITHELIAL CELL ADHESION MOLECULE PRECURSOR LEPOC|Ensembl=ENSLOCG00000013312.1|UniProtKB=W5N6Z5 W5N6Z5 PTHR24327:SF28 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005891.1|UniProtKB=W5MFF7 W5MFF7 COPS7B PTHR15350:SF5 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002802.1|UniProtKB=W5M4J1 W5M4J1 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 3 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000016857.1|UniProtKB=W5NJN1 W5NJN1 PTHR12844:SF17 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006156.1|UniProtKB=W5MGF7 W5MGF7 PTHR24023:SF569 COLLAGEN ALPHA COLLAGEN ALPHA-1(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000003664.1|UniProtKB=W5M7L4 W5M7L4 PTHR12156:SF23 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 1 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011003.1|UniProtKB=W5MYP8 W5MYP8 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004042.1|UniProtKB=W5M8X0 W5M8X0 PTHR12864:SF54 RAN BINDING PROTEIN 9-RELATED SPRY DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018238.1|UniProtKB=W5NNY0 W5NNY0 PTHR21011:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008797.1|UniProtKB=W5MQP8 W5MQP8 ICE1 PTHR11852:SF4 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE LITTLE ELONGATION COMPLEX SUBUNIT 1 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013447.1|UniProtKB=W5N7H7 W5N7H7 PTHR10877:SF114 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;cytoskeletal protein binding#GO:0008092;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated channel activity#GO:0022832;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;signaling receptor binding#GO:0005102;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;cation binding#GO:0043169;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 negative regulation of biological process#GO:0048519;detection of mechanical stimulus#GO:0050982;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;detection of stimulus#GO:0051606;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;negative regulation of sequestering of calcium ion#GO:0051283 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014042.1|UniProtKB=W5N9J7 W5N9J7 TTC9 PTHR11242:SF15 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9A chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007883.1|UniProtKB=W5MMG5 W5MMG5 PTHR32465:SF0 BARDET-BIEDL SYNDROME 2 PROTEIN BARDET-BIEDL SYNDROME 2 PROTEIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;motile cilium#GO:0031514;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000015020.1|UniProtKB=W5NCY0 W5NCY0 PTHR14889:SF2 RCG36411 GENE 6377-RELATED LEPOC|Ensembl=ENSLOCG00000003521.1|UniProtKB=W5M711 W5M711 PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN BOS COMPLEX SUBUNIT TMEM147 LEPOC|Ensembl=ENSLOCG00000001275.1|UniProtKB=W5LZA1 W5LZA1 PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE decarboxylase#PC00089 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 LEPOC|Ensembl=ENSLOCG00000000862.1|UniProtKB=W5LXW0 W5LXW0 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000006259.1|UniProtKB=W5MGQ1 W5MGQ1 PTHR21290:SF28 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;phosphate-containing compound metabolic process#GO:0006796;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012781.1|UniProtKB=W5N520 W5N520 PTHR12191:SF22 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP6 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006887.1|UniProtKB=W5MIX1 W5MIX1 ZNF335 PTHR24403:SF36 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 335 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010659.1|UniProtKB=W5MXF2 W5MXF2 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003100.1|UniProtKB=W5M5L8 W5M5L8 PTHR46501:SF7 MYOMEGALIN MYOMEGALIN ISOFORM X1 regulation of microtubule-based process#GO:0032886;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011427.1|UniProtKB=W5N088 W5N088 PTHR15692:SF19 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;Notch signaling pathway#GO:0007219;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Notch signaling pathway#P00045>Mastermind#P01106 LEPOC|Ensembl=ENSLOCG00000015258.1|UniProtKB=W5NDR7 W5NDR7 PTHR12619:SF5 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001235.1|UniProtKB=W5LZ41 W5LZ41 PTHR10201:SF306 MATRIX METALLOPROTEINASE MATRILYSIN-LIKE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006606.1|UniProtKB=W5MHX0 W5MHX0 PP2D1 PTHR13832:SF837 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006869.1|UniProtKB=W5MIU8 W5MIU8 PTHR24377:SF929 IP01015P-RELATED ZINC FINGER PROTEIN 665 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006057.1|UniProtKB=W5MG06 W5MG06 ACTA2 PTHR11937:SF445 ACTIN ACTIN, AORTIC SMOOTH MUSCLE intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000015325.1|UniProtKB=W5NDZ9 W5NDZ9 PTHR15260:SF1 SARCOSPAN SARCOSPAN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 LEPOC|Ensembl=ENSLOCG00000005699.1|UniProtKB=W5MEV1 W5MEV1 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;DNA-templated transcription#GO:0006351;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000017795.1|UniProtKB=W5NMP0 W5NMP0 PTHR10704:SF5 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 7 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;amino sugar metabolic process#GO:0006040;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003057.1|UniProtKB=W5M5K3 W5M5K3 PTHR22730:SF3 PROMININ PROM PROTEIN PROMININ-1 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 microvillus#GO:0005902;extracellular region#GO:0005576;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;cell surface#GO:0009986;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016219.1|UniProtKB=W5NH93 W5NH93 PTHR46957:SF2 CYTOKINE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE BETA cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;protein metabolic process#GO:0019538;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;multicellular organism development#GO:0007275;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;negative regulation of phosphate metabolic process#GO:0045936;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 receptor complex#GO:0043235;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VE-PTP#P00250 LEPOC|Ensembl=ENSLOCG00000016494.1|UniProtKB=W5NIC0 W5NIC0 PTHR46513:SF40 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 LEPOC|Ensembl=ENSLOCG00000003756.1|UniProtKB=W5M7X5 W5M7X5 PTHR23512:SF3 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016171.1|UniProtKB=W5NH16 W5NH16 PTHR12696:SF1 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013815.1|UniProtKB=W5N8T2 W5N8T2 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005132.1|UniProtKB=W5MCU8 W5MCU8 PTHR18952:SF104 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001995.1|UniProtKB=W5M1R1 W5M1R1 PTHR43563:SF11 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] A nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000007820.1|UniProtKB=W5MM96 W5MM96 PTHR10799:SF76 SNF2/RAD54 HELICASE FAMILY TRANSCRIPTION ACTIVATOR BRG1 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;protein binding#GO:0005515;transcription factor binding#GO:0008134 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000014256.1|UniProtKB=W5NA92 W5NA92 PTHR10256:SF1 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017550.1|UniProtKB=W5NLZ6 W5NLZ6 PTHR12002:SF3 CLAUDIN CLAUDIN-23 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000015836.1|UniProtKB=W5NFT5 W5NFT5 PTHR14332:SF3 DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018078.1|UniProtKB=W5NNH0 W5NNH0 PTHR15503:SF39 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006748.1|UniProtKB=W5MIE6 W5MIE6 PTHR47979:SF3 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;vesicle organization#GO:0016050;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002253.1|UniProtKB=W5M2L8 W5M2L8 PTHR12650:SF15 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI RIBOSOMAL PROTEIN S30, ISOFORM A cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011987.1|UniProtKB=W5N283 W5N283 PTHR11158:SF33 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING 1 phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014932.1|UniProtKB=W5NCM8 W5NCM8 PTHR47174:SF3 BRIDGING INTEGRATOR 3 BRIDGING INTEGRATOR 3 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016669.1|UniProtKB=W5NIY6 W5NIY6 PTHR15720:SF13 GREB1-RELATED PROTEIN GREB1 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000014695.1|UniProtKB=W5NBT9 W5NBT9 PTHR24372:SF70 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012792.1|UniProtKB=W5N536 W5N536 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005002.1|UniProtKB=W5MCB5 W5MCB5 PTHR11662:SF279 SOLUTE CARRIER FAMILY 17 VOLTAGE-GATED PURINE NUCLEOTIDE UNIPORTER SLC17A9 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017006.1|UniProtKB=W5NK60 W5NK60 PTHR24356:SF138 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;peptidyl-serine phosphorylation#GO:0018105;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;positive regulation of programmed cell death#GO:0043068;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;hippo signaling#GO:0035329;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002110.1|UniProtKB=W5M269 W5M269 PTHR11339:SF228 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000018338.1|UniProtKB=W5NP80 W5NP80 PTHR10270:SF27 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 sensory organ morphogenesis#GO:0090596;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;eye morphogenesis#GO:0048592;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;central nervous system development#GO:0007417;negative regulation of DNA-templated transcription#GO:0045892;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;negative regulation of metabolic process#GO:0009892;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;camera-type eye morphogenesis#GO:0048593;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000007718.1|UniProtKB=W5MLX7 W5MLX7 PTHR12419:SF7 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 3 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013508.1|UniProtKB=W5N7P7 W5N7P7 PTHR23313:SF0 TSEC1-RELATED TESTIS-EXPRESSED PROTEIN 9 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000010311.1|UniProtKB=W5MW79 W5MW79 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000013292.1|UniProtKB=W5N6W2 W5N6W2 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000017742.1|UniProtKB=W5NMI7 W5NMI7 PTHR11214:SF19 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 2 UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000003920.1|UniProtKB=W5M8H3 W5M8H3 PTHR11477:SF13 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN DEATH-INDUCER OBLITERATOR 1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000017818.1|UniProtKB=W5NMR3 W5NMR3 PTHR10339:SF25 ADP-RIBOSYLTRANSFERASE SECRETED EXOENZYME S transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009983.1|UniProtKB=W5MV01 W5MV01 ZNF462 PTHR24388:SF99 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF52.1-LIKE ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010946.1|UniProtKB=W5MYH5 W5MYH5 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012839.1|UniProtKB=W5N5C0 W5N5C0 PTHR23175:SF5 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 23 LEPOC|Ensembl=ENSLOCG00000012686.1|UniProtKB=W5N4P7 W5N4P7 PTHR32014:SF2 BCL-2-MODIFYING FACTOR BCL-2-MODIFYING FACTOR positive regulation of apoptotic process#GO:0043065;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of programmed cell death#GO:0043067;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017681.1|UniProtKB=W5NMC7 W5NMC7 ANKRD34A PTHR24156:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN 34A LEPOC|Ensembl=ENSLOCG00000010681.1|UniProtKB=W5MXI3 W5MXI3 PTHR11588:SF53 TUBULIN TUBULIN ALPHA-4A CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006861.1|UniProtKB=W5MIT7 W5MIT7 PTHR12015:SF177 SMALL INDUCIBLE CYTOKINE A CHEMOKINE INTERLEUKIN-8-LIKE DOMAIN-CONTAINING PROTEIN cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010194.1|UniProtKB=W5MVS5 W5MVS5 PTHR10217:SF533 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 5 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011894.1|UniProtKB=W5N1X5 W5N1X5 PTHR24347:SF451 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005167.1|UniProtKB=W5MCW6 W5MCW6 RTKN PTHR21538:SF19 ANILLIN/RHOTEKIN RTKN RHOTEKIN cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring assembly#GO:0000915;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 actomyosin contractile ring#GO:0005826;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell division site#GO:0032153;contractile ring#GO:0070938;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005802.1|UniProtKB=W5MF50 W5MF50 PTHR47977:SF8 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-34 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;vacuole organization#GO:0007033;establishment of localization#GO:0051234;vesicle organization#GO:0016050;organelle fusion#GO:0048284;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;vesicle-mediated transport to the plasma membrane#GO:0098876;phagocytosis#GO:0006909;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;protein transport#GO:0015031;lytic vacuole organization#GO:0080171;import into cell#GO:0098657 Golgi cisterna#GO:0031985;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endocytic vesicle#GO:0030139 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001491.1|UniProtKB=W5LZZ5 W5LZZ5 PTHR45704:SF16 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR LEPOC|Ensembl=ENSLOCG00000014748.1|UniProtKB=W5NC03 W5NC03 PTHR45783:SF1 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 3 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000003613.1|UniProtKB=W5M7E5 W5M7E5 PTHR15683:SF6 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003216.1|UniProtKB=W5M6J0 W5M6J0 PTHR23317:SF77 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 9 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000013938.1|UniProtKB=W5N974 W5N974 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000005455.1|UniProtKB=W5MDW8 W5MDW8 PTHR45762:SF14 ZINC FINGER RNA-BINDING PROTEIN SI:CH211-197H24.6 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008466.1|UniProtKB=W5MPJ0 W5MPJ0 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007964.1|UniProtKB=W5MMR7 W5MMR7 PTHR12411:SF971 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN K cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011228.1|UniProtKB=W5MZI7 W5MZI7 IFT27 PTHR24070:SF414 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY INTRAFLAGELLAR TRANSPORT 27 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012847.1|UniProtKB=W5N5B0 W5N5B0 PTHR12424:SF6 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017880.1|UniProtKB=W5NMX4 W5NMX4 PTHR11984:SF33 CONNEXIN GAP JUNCTION ALPHA-1 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 regulation of biological process#GO:0050789;system development#GO:0048731;heart development#GO:0007507;circulatory system development#GO:0072359;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000012374.1|UniProtKB=W5N3M6 W5N3M6 PTHR18945:SF393 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular component biogenesis#GO:0044085;regulation of postsynaptic membrane potential#GO:0060078;transport#GO:0006810;developmental process#GO:0032502;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular component assembly#GO:0022607;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;monoatomic ion transmembrane transport#GO:0034220;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011960.1|UniProtKB=W5N247 W5N247 PTHR23320:SF157 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED SI:CH1073-291C23.2 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005873.1|UniProtKB=W5MFD7 W5MFD7 PTHR24418:SF245 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE HCK protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230 LEPOC|Ensembl=ENSLOCG00000012224.1|UniProtKB=W5N327 W5N327 PTHR46169:SF25 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 1-LIKE-RELATED regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013618.1|UniProtKB=W5N832 W5N832 PTHR44464:SF1 WD REPEAT-CONTAINING PROTEIN 17 WD REPEAT-CONTAINING PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000011697.1|UniProtKB=W5N168 W5N168 PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016726.1|UniProtKB=W5NJ57 W5NJ57 PTHR12990:SF9 ARMET-LIKE PROTEIN CEREBRAL DOPAMINE NEUROTROPHIC FACTOR cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002306.1|UniProtKB=W5M2T4 W5M2T4 PTHR24060:SF162 METABOTROPIC GLUTAMATE RECEPTOR TASTE RECEPTOR TYPE 1 MEMBER 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009845.1|UniProtKB=W5MUH5 W5MUH5 MATN2 PTHR24034:SF155 EGF-LIKE DOMAIN-CONTAINING PROTEIN MATRILIN 2 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000017565.1|UniProtKB=W5NM11 W5NM11 FBXO46 PTHR16271:SF10 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 46 LEPOC|Ensembl=ENSLOCG00000005600.1|UniProtKB=W5MEF3 W5MEF3 PTHR46004:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 LEPOC|Ensembl=ENSLOCG00000017680.1|UniProtKB=W5NMC6 W5NMC6 PTHR15404:SF2 PROTEIN AF1Q PROTEIN AF1Q positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of organelle organization#GO:0010638;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of mitochondrion organization#GO:0010821;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;regulation of organelle organization#GO:0033043;regulation of membrane potential#GO:0042391;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of membrane depolarization#GO:0003254;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002772.1|UniProtKB=W5M4F1 W5M4F1 PTHR48025:SF1 OS02G0815200 PROTEIN RRM DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003582.1|UniProtKB=W5M793 W5M793 PTHR10334:SF73 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002036.1|UniProtKB=W5M1V7 W5M1V7 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015840.1|UniProtKB=W5NFU2 W5NFU2 SCARA5 PTHR19331:SF482 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CLASS A MEMBER 5 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013963.1|UniProtKB=W5N9A5 W5N9A5 PTHR46149:SF2 MIP08469P GTP-BINDING PROTEIN RHES protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000007120.1|UniProtKB=W5MJR2 W5MJR2 PTHR24390:SF238 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014528.1|UniProtKB=W5NB86 W5NB86 PTHR18966:SF151 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 3 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;neurotransmitter receptor activity#GO:0030594;organic anion transmembrane transporter activity#GO:0008514;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;amino acid transmembrane transporter activity#GO:0015171;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu3#P01016;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 LEPOC|Ensembl=ENSLOCG00000001447.1|UniProtKB=W5LZU0 W5LZU0 PTHR43758:SF2 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000840.1|UniProtKB=W5LXT4 W5LXT4 PTHR10131:SF146 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor binding#GO:0005164;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of NF-kappaB transcription factor activity#GO:0051092;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cell communication#GO:0010646;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013599.1|UniProtKB=W5N809 W5N809 PTHR23239:SF180 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 17 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000014936.1|UniProtKB=W5NCM9 W5NCM9 PTHR23235:SF147 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004561.1|UniProtKB=W5MAQ1 W5MAQ1 PTHR45682:SF10 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 13 ISOFORM B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000006914.1|UniProtKB=W5MJ09 W5MJ09 PTHR15829:SF1 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 1 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003816.1|UniProtKB=W5M874 W5M874 PTHR11706:SF33 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;iron ion transmembrane transport#GO:0034755;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011247.1|UniProtKB=W5MZL1 W5MZL1 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000580.1|UniProtKB=W5LWY5 W5LWY5 CREM PTHR45879:SF4 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CAMP-RESPONSIVE ELEMENT MODULATOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Enkephalin release#P05913>CREB#P05971;Apoptosis signaling pathway#P00006>ATF#P00302;CCKR signaling map#P06959>ICER#P07027;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000007705.1|UniProtKB=W5MLV0 W5MLV0 PTHR45677:SF11 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 2 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000006031.1|UniProtKB=W5MFX8 W5MFX8 PTHR10884:SF14 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009597.1|UniProtKB=W5MTL6 W5MTL6 PTHR11902:SF30 ENOLASE ENOLASE 4 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000011345.1|UniProtKB=W5MZZ3 W5MZZ3 PTHR10649:SF9 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008910.1|UniProtKB=W5MR49 W5MR49 PTHR22770:SF45 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein binding#GO:0032182;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001852.1|UniProtKB=W5M1D0 W5M1D0 PTHR12185:SF16 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transmembrane transporter activity#GO:0022857;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleobase-containing compound transmembrane transporter activity#GO:0015932;double-stranded RNA binding#GO:0003725;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;RNA localization#GO:0006403 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011372.1|UniProtKB=W5N022 W5N022 CASKIN2 PTHR24174:SF18 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 CASKIN-2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001336.1|UniProtKB=W5LZH6 W5LZH6 PTHR23255:SF64 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2A signaling receptor activity#GO:0038023;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII#P06747;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780 LEPOC|Ensembl=ENSLOCG00000005509.1|UniProtKB=W5ME44 W5ME44 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000006587.1|UniProtKB=W5MHU3 W5MHU3 PTHR15417:SF5 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;phosphatase inhibitor#PC00183 LEPOC|Ensembl=ENSLOCG00000002311.1|UniProtKB=W5M2W3 W5M2W3 PTHR44080:SF1 E3 UBIQUITIN-PROTEIN LIGASE COP1 E3 UBIQUITIN-PROTEIN LIGASE COP1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 P53 pathway feedback loops 1#P04392>Cop-1#P04540;P53 pathway feedback loops 1#P04392>Cop-1#G04683 LEPOC|Ensembl=ENSLOCG00000010046.1|UniProtKB=W5MV85 W5MV85 PTHR15691:SF6 WASH COMPLEX SUBUNIT 5 WASH COMPLEX SUBUNIT 5 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;vesicle organization#GO:0016050;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001764.1|UniProtKB=W5M0Y3 W5M0Y3 PTHR10026:SF43 CYCLIN CYCLIN-T2 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000001533.1|UniProtKB=W5M045 W5M045 PTHR10343:SF84 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000003368.1|UniProtKB=W5M6H6 W5M6H6 PTHR47640:SF11 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED RNA-BINDING PROTEIN 42 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 LEPOC|Ensembl=ENSLOCG00000001662.1|UniProtKB=W5M0L2 W5M0L2 PTHR24002:SF3 SOLUTE CARRIER FAMILY 22 MEMBER 18 SOLUTE CARRIER FAMILY 22 MEMBER 18 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008658.1|UniProtKB=W5MQ72 W5MQ72 CREB3L4 PTHR45996:SF2 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000006675.1|UniProtKB=W5MI56 W5MI56 PTHR15597:SF45 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;multicellular organism development#GO:0007275;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007090.1|UniProtKB=W5MJN0 W5MJN0 PTHR24351:SF171 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>S6K#P04636;PI3 kinase pathway#P00048>S6K#P01194;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000004405.1|UniProtKB=W5MA66 W5MA66 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 FATTY-ACID PEROXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000350.1|UniProtKB=W5LW75 W5LW75 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002816.1|UniProtKB=W5M4K4 W5M4K4 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007342.1|UniProtKB=W5MKI1 W5MKI1 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016320.1|UniProtKB=W5NHP1 W5NHP1 PTHR24184:SF11 SI:CH211-189E2.2 ANKYRIN REPEAT AND SOCS BOX CONTAINING 3 LEPOC|Ensembl=ENSLOCG00000017754.1|UniProtKB=W5NMJ9 W5NMJ9 PTHR24241:SF195 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016662.1|UniProtKB=W5NIX3 W5NIX3 PTHR10137:SF4 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009823.1|UniProtKB=W5MUE9 W5MUE9 PTHR23327:SF6 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002184.1|UniProtKB=W5M2F8 W5M2F8 PTHR46304:SF1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016478.1|UniProtKB=W5NI97 W5NI97 PTHR12422:SF4 GH09096P CYFIP-RELATED RAC1 INTERACTOR A LEPOC|Ensembl=ENSLOCG00000008561.1|UniProtKB=W5MPV1 W5MPV1 PTHR14392:SF3 NIBAN FAMILY MEMBER PROTEIN NIBAN 1 LEPOC|Ensembl=ENSLOCG00000010114.1|UniProtKB=W5MVG4 W5MVG4 PTHR24006:SF842 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 40 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015435.1|UniProtKB=W5NED4 W5NED4 PTHR46144:SF3 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER MATRIN-TYPE PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000013193.1|UniProtKB=W5N6J4 W5N6J4 PTHR11624:SF96 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013696.1|UniProtKB=W5N8C7 W5N8C7 PTHR19871:SF43 BETA TRANSDUCIN-RELATED PROTEIN SI:CH211-212K18.6 LEPOC|Ensembl=ENSLOCG00000010202.1|UniProtKB=W5MVT4 W5MVT4 PTHR24072:SF17 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOJ GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Rac#P00564;Huntington disease#P00029>Rac#P00775;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 LEPOC|Ensembl=ENSLOCG00000011917.1|UniProtKB=W5N1Z3 W5N1Z3 PTHR46271:SF3 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINAL HOMEOBOX PROTEIN RX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015632.1|UniProtKB=W5NF35 W5NF35 PTHR21037:SF3 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014825.1|UniProtKB=W5NC96 W5NC96 PTHR10366:SF564 NAD DEPENDENT EPIMERASE/DEHYDRATASE STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005851.1|UniProtKB=W5MFA2 W5MFA2 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 21 binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;amide binding#GO:0033218 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001882.1|UniProtKB=W5M1C1 W5M1C1 PTHR32008:SF2 MATURIN MATURIN regulation of myeloid cell differentiation#GO:0045637;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;regulation of signaling#GO:0023051;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of hemopoiesis#GO:1903706;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016029.1|UniProtKB=W5NGI7 W5NGI7 PTHR46857:SF2 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE F-BOX ONLY PROTEIN 16 LEPOC|Ensembl=ENSLOCG00000010762.1|UniProtKB=W5MXS6 W5MXS6 PTHR11592:SF41 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 1 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;response to oxygen-containing compound#GO:1901700;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;response to reactive oxygen species#GO:0000302;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001081.1|UniProtKB=W5LYL1 W5LYL1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012090.1|UniProtKB=W5N2M1 W5N2M1 MYL5 PTHR23049:SF8 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN LIGHT CHAIN 5 cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017420.1|UniProtKB=W5NLL6 W5NLL6 PTHR39158:SF1 OS08G0560600 PROTEIN DNAJ HOMOLOG SUBFAMILY C MEMBER 28 LEPOC|Ensembl=ENSLOCG00000010590.1|UniProtKB=W5MX71 W5MX71 TBC1D8 PTHR22957:SF260 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005062.1|UniProtKB=W5MCI6 W5MCI6 PTHR45623:SF20 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 sensory organ morphogenesis#GO:0090596;protein-DNA complex organization#GO:0071824;heart development#GO:0007507;animal organ development#GO:0048513;developmental process#GO:0032502;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;ear development#GO:0043583;chordate embryonic development#GO:0043009;cellular component organization or biogenesis#GO:0071840;embryonic organ development#GO:0048568;embryo development#GO:0009790;inner ear development#GO:0048839;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;inner ear morphogenesis#GO:0042472;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;chromatin organization#GO:0006325;sensory organ development#GO:0007423;chromatin remodeling#GO:0006338;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009373.1|UniProtKB=W5MSS7 W5MSS7 PTHR22573:SF27 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-LIKE PROTEIN 5 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;muscle tissue development#GO:0060537;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytosol#GO:0005829;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000013743.1|UniProtKB=W5N8J0 W5N8J0 PTHR32546:SF7 G-PROTEIN COUPLED RECEPTOR 158-RELATED G-PROTEIN COUPLED RECEPTOR 179-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008765.1|UniProtKB=W5MQL1 W5MQL1 PTHR33198:SF20 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005384.1|UniProtKB=W5MDN1 W5MDN1 PTHR43888:SF31 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 2 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011532.1|UniProtKB=W5N0L0 W5N0L0 PTHR31169:SF4 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED 7-LIKE PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009443.1|UniProtKB=W5MT31 W5MT31 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;guanyl-nucleotide exchange factor complex#GO:0032045 LEPOC|Ensembl=ENSLOCG00000010233.1|UniProtKB=W5MVX4 W5MVX4 PTHR45667:SF9 S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN MITOCHONDRIAL S-ADENOSYLMETHIONINE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012900.1|UniProtKB=W5N5H2 W5N5H2 PTHR15371:SF39 TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM23 protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008668.1|UniProtKB=W5MQB1 W5MQB1 PTHR11339:SF396 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED SCO-SPONDIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000001110.1|UniProtKB=W5LYP7 W5LYP7 PTHR11782:SF33 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000016042.1|UniProtKB=W5NGK0 W5NGK0 PTHR22984:SF24 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002439.1|UniProtKB=W5M3B7 W5M3B7 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>19S proteasome#P01209;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000003575.1|UniProtKB=W5M781 W5M781 TIMM22 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 signal sequence binding#GO:0005048;protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011115.1|UniProtKB=W5MZ47 W5MZ47 PTHR24100:SF0 BUTYROPHILIN V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015330.1|UniProtKB=W5NE05 W5NE05 PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A LIKE cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013949.1|UniProtKB=W5N991 W5N991 PTHR12294:SF10 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 3, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;cation channel complex#GO:0034703;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000011405.1|UniProtKB=W5N067 W5N067 PTHR24012:SF733 RNA BINDING PROTEIN TIA1 CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN LIKE 1 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014465.1|UniProtKB=W5NAZ9 W5NAZ9 PTHR24031:SF221 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-I nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000014481.1|UniProtKB=W5NB14 W5NB14 PTHR14571:SF8 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 23 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of organelle assembly#GO:1902115;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of metabolic process#GO:0009892;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of autophagosome maturation#GO:1901096;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000807.1|UniProtKB=W5LXP7 W5LXP7 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000006653.1|UniProtKB=W5MI24 W5MI24 PTHR15272:SF0 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018323.1|UniProtKB=W5NP65 W5NP65 TMEM158 PTHR38324:SF1 TRANSMEMBRANE PROTEIN 158 TRANSMEMBRANE PROTEIN 158 LEPOC|Ensembl=ENSLOCG00000009132.1|UniProtKB=W5MRX6 W5MRX6 PTHR12752:SF2 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PDZ AND PLECKSTRIN HOMOLOGY DOMAINS 1 LEPOC|Ensembl=ENSLOCG00000014798.1|UniProtKB=W5NC64 W5NC64 PTHR15666:SF1 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013118.1|UniProtKB=W5N6A4 W5N6A4 PTHR23122:SF35 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 2 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017381.1|UniProtKB=W5NLH7 W5NLH7 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011927.1|UniProtKB=W5N205 W5N205 PTHR11193:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;pICln-Sm protein complex#GO:0034715;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015074.1|UniProtKB=W5ND40 W5ND40 PTHR23211:SF0 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN TGN38 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN 2 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001523.1|UniProtKB=W5M027 W5M027 PTHR24120:SF3 GH07239P ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000003589.1|UniProtKB=W5M7C3 W5M7C3 PTHR31350:SF21 SI:DKEY-261L7.2 F-BOX ONLY PROTEIN 21 LEPOC|Ensembl=ENSLOCG00000011798.1|UniProtKB=W5N1J6 W5N1J6 PTHR45946:SF3 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-A1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002411.1|UniProtKB=W5M369 W5M369 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001207.1|UniProtKB=W5LZ00 W5LZ00 MMP20 PTHR10201:SF125 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-20 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 odontogenesis of dentin-containing tooth#GO:0042475;animal organ development#GO:0048513;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;odontogenesis#GO:0042476;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;amelogenesis#GO:0097186;external encapsulating structure organization#GO:0045229;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;catabolic process#GO:0009056;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000009707.1|UniProtKB=W5MU02 W5MU02 PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1 cellular component biogenesis#GO:0044085;developmental process#GO:0032502;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;nervous system development#GO:0007399;modification-dependent macromolecule catabolic process#GO:0043632;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;cell junction assembly#GO:0034329;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501 SCF ubiquitin ligase complex#GO:0019005;synapse#GO:0045202;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003694.1|UniProtKB=W5M7N7 W5M7N7 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009715.1|UniProtKB=W5MU11 W5MU11 PTHR10113:SF10 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002484.1|UniProtKB=W5M3F5 W5M3F5 PTHR45925:SF4 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 217 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010158.1|UniProtKB=W5MVN0 W5MVN0 PTHR10379:SF5 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006242.1|UniProtKB=W5MGM9 W5MGM9 PTHR12411:SF929 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN Z cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005147.1|UniProtKB=W5MCT7 W5MCT7 PTHR23411:SF49 TAPASIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016843.1|UniProtKB=W5NJL2 W5NJL2 PTHR19282:SF198 TETRASPANIN TETRASPANIN-11 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001230.1|UniProtKB=W5LZ58 W5LZ58 OLFML2B PTHR23192:SF37 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2B regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005359.1|UniProtKB=W5MDJ8 W5MDJ8 PTHR10671:SF9 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS FIBER MEMBRANE INTRINSIC PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012272.1|UniProtKB=W5N393 W5N393 MCUB PTHR13462:SF6 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER REGULATORY SUBUNIT MCUB, MITOCHONDRIAL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000003598.1|UniProtKB=W5M7B0 W5M7B0 PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012841.1|UniProtKB=W5N5A3 W5N5A3 PTHR24027:SF322 CADHERIN-23 CADHERIN-6 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;cell junction assembly#GO:0034329;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000013113.1|UniProtKB=W5N695 W5N695 PTHR21325:SF45 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000004768.1|UniProtKB=W5MBG5 W5MBG5 PTHR46514:SF1 AMPHIPHYSIN BRIDGING INTEGRATOR 2 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;phagocytosis#GO:0006909;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;non-membrane-bounded organelle assembly#GO:0140694;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010422.1|UniProtKB=W5MWM5 W5MWM5 PTHR44329:SF9 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;immune response#GO:0006955;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;defense response to symbiont#GO:0140546;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;positive regulation of intracellular signal transduction#GO:1902533;defense response#GO:0006952;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012804.1|UniProtKB=W5N548 W5N548 PTHR22950:SF646 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 10-RELATED L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009430.1|UniProtKB=W5MSZ6 W5MSZ6 PTHR34491:SF113 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED FIBRONECTIN TYPE III DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G14620) LEPOC|Ensembl=ENSLOCG00000011289.1|UniProtKB=W5MZR5 W5MZR5 SOSTDC1 PTHR14903:SF5 SCLEROSTIN-RELATED SCLEROSTIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000223.1|UniProtKB=W5LVU1 W5LVU1 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017386.1|UniProtKB=W5NLI2 W5NLI2 PTHR38505:SF1 HYPOTHETICAL PROTEIN LOC100362176 RIKEN CDNA 1110032F04 GENE LEPOC|Ensembl=ENSLOCG00000000590.1|UniProtKB=W5LWZ7 W5LWZ7 PTHR12300:SF133 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 6 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011093.1|UniProtKB=W5MZ26 W5MZ26 PTHR12181:SF11 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;lipid catabolic process#GO:0016042;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;response to insulin#GO:0032868;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;positive regulation of biosynthetic process#GO:0009891;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;glycerolipid biosynthetic process#GO:0045017;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;fatty acid catabolic process#GO:0009062;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000014650.1|UniProtKB=W5NBM2 W5NBM2 PTHR22847:SF736 WD40 REPEAT PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005145.1|UniProtKB=W5MCT2 W5MCT2 PTHR16083:SF87 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 20 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007749.1|UniProtKB=W5MM05 W5MM05 PTHR22809:SF3 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000000655.1|UniProtKB=W5LXA8 W5LXA8 PTHR11932:SF174 CULLIN CULLIN-2 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Cul-1#P01239 LEPOC|Ensembl=ENSLOCG00000006740.1|UniProtKB=W5MIG1 W5MIG1 PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004843.1|UniProtKB=W5MBR1 W5MBR1 PTHR24064:SF470 SOLUTE CARRIER FAMILY 22 MEMBER SI:DKEY-166K12.1 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006986.1|UniProtKB=W5MJA0 W5MJA0 PTHR48026:SF12 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017764.1|UniProtKB=W5NMK9 W5NMK9 PTHR16155:SF3 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005412.1|UniProtKB=W5MDR8 W5MDR8 PTHR10405:SF29 SPINDLIN SPINDLIN-W-LIKE chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015255.1|UniProtKB=W5NDR3 W5NDR3 PTHR22798:SF0 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006709.1|UniProtKB=W5MI97 W5MI97 PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002507.1|UniProtKB=W5M3J7 W5M3J7 PTHR45627:SF7 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 5 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 LEPOC|Ensembl=ENSLOCG00000011600.1|UniProtKB=W5N0U5 W5N0U5 WARS1 PTHR10055:SF1 TRYPTOPHANYL-TRNA SYNTHETASE TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017475.1|UniProtKB=W5NLS1 W5NLS1 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011765.1|UniProtKB=W5N1H4 W5N1H4 PTHR10502:SF19 ANNEXIN ANNEXIN A6 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of localization#GO:0032879;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;apoptotic process#GO:0006915;cell death#GO:0008219;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;programmed cell death#GO:0012501;cell communication#GO:0007154;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000011852.1|UniProtKB=W5N1R9 W5N1R9 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011754.1|UniProtKB=W5N1E7 W5N1E7 PTHR45620:SF18 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004566.1|UniProtKB=W5MAQ6 W5MAQ6 PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;RNA polymerase II preinitiation complex assembly#GO:0051123;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002839.1|UniProtKB=W5M4Q3 W5M4Q3 PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015288.1|UniProtKB=W5NDV4 W5NDV4 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008448.1|UniProtKB=W5MPH5 W5MPH5 PTHR46474:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 1 TWO PORE CHANNEL PROTEIN 1 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 ion channel#PC00133;transporter#PC00227 CCKR signaling map#P06959>TPC1/2#P07209 LEPOC|Ensembl=ENSLOCG00000011123.1|UniProtKB=W5MZ57 W5MZ57 PTHR14972:SF3 AGAP011572-PA GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001399.1|UniProtKB=W5LZN4 W5LZN4 PTHR12157:SF25 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 3 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004577.1|UniProtKB=W5MAS1 W5MAS1 PTHR24240:SF189 OPSIN TELEOST MULTIPLE TISSUE OPSIN A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004883.1|UniProtKB=W5MBX0 W5MBX0 PTHR19212:SF6 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012411.1|UniProtKB=W5N3S2 W5N3S2 PTHR10797:SF1 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000000492.1|UniProtKB=W5LWX6 W5LWX6 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000007259.1|UniProtKB=W5MK78 W5MK78 VAV1 PTHR45818:SF2 PROTEIN VAV PROTO-ONCOGENE VAV nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;cell motility#GO:0048870;cell migration#GO:0016477;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 LEPOC|Ensembl=ENSLOCG00000016218.1|UniProtKB=W5NH89 W5NH89 PTHR45614:SF5 MYB PROTEIN-RELATED TRANSCRIPTIONAL ACTIVATOR MYB sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;mitotic cell cycle#GO:0000278;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008640.1|UniProtKB=W5MQ45 W5MQ45 PTHR24104:SF21 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 LEPOC|Ensembl=ENSLOCG00000011043.1|UniProtKB=W5MYV2 W5MYV2 PTHR45632:SF4 LD33804P KELCH-LIKE PROTEIN 36 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014610.1|UniProtKB=W5NBI0 W5NBI0 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;phosphorylation#GO:0016310;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;reticulophagy#GO:0061709;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;autophagosome assembly#GO:0000045;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001071.1|UniProtKB=W5LYJ8 W5LYJ8 PTHR24349:SF468 SERINE/THREONINE-PROTEIN KINASE RIBOSOMAL PROTEIN S6 KINASE A4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein kinase binding#GO:0019901;mitogen-activated protein kinase binding#GO:0051019;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006770.1|UniProtKB=W5MIJ3 W5MIJ3 PTHR11226:SF3 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 1 UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;protein binding#GO:0005515;glucosyltransferase activity#GO:0046527;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein N-linked glycosylation#GO:0006487;cellular response to stress#GO:0033554;glycosylation#GO:0070085 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000844.1|UniProtKB=W5LXT3 W5LXT3 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013307.1|UniProtKB=W5N6Y9 W5N6Y9 PTHR24327:SF86 HOMEOBOX PROTEIN DISTAL-LESS HOMEOBOX 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005308.1|UniProtKB=W5MDD7 W5MDD7 PTHR31622:SF1 TRANSMEMBRANE PROTEIN 218 TRANSMEMBRANE PROTEIN 218 LEPOC|Ensembl=ENSLOCG00000011793.1|UniProtKB=W5N1J3 W5N1J3 PTHR12290:SF10 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 1 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014564.1|UniProtKB=W5NBC1 W5NBC1 PTHR11915:SF232 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003494.1|UniProtKB=W5M6Y4 W5M6Y4 PTHR46806:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN CONTAINING 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003488.1|UniProtKB=W5M6X7 W5M6X7 PTHR10681:SF171 THIOREDOXIN PEROXIDASE PEROXIREDOXIN 4 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular homeostasis#GO:0019725;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006481.1|UniProtKB=W5MHH8 W5MHH8 PTHR31139:SF4 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG ECTOPIC P GRANULES PROTEIN 5 HOMOLOG process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;protein-containing complex organization#GO:0043933;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagosome maturation#GO:0097352;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013705.1|UniProtKB=W5N8D7 W5N8D7 PTHR24247:SF32 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2C signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;monoatomic cation transport#GO:0006812;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;transmembrane transport#GO:0055085;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;calcium ion transmembrane transport#GO:0070588;trans-synaptic signaling#GO:0099537;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000012044.1|UniProtKB=W5N2G7 W5N2G7 PTHR13561:SF20 DNA REPLICATION REGULATOR DPB11-RELATED DNA TOPOISOMERASE 2-BINDING PROTEIN 1 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001756.1|UniProtKB=W5M0Z7 W5M0Z7 PTHR11134:SF9 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-2 COMPLEX SUBUNIT BETA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003682.1|UniProtKB=W5M7L5 W5M7L5 PTHR12247:SF86 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011127.1|UniProtKB=W5MZ58 W5MZ58 PTHR10188:SF42 L-ASPARAGINASE SI:CH211-256M1.8 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;aspartate family amino acid metabolic process#GO:0009066;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017352.1|UniProtKB=W5NLE8 W5NLE8 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;U2 snRNP#GO:0005686;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014464.1|UniProtKB=W5NAZ6 W5NAZ6 PTHR15668:SF4 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteolysis#GO:0045862;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of metabolic process#GO:0019222 LEPOC|Ensembl=ENSLOCG00000010125.1|UniProtKB=W5MVI9 W5MVI9 PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011749.1|UniProtKB=W5N1D5 W5N1D5 PTHR10903:SF170 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000018217.1|UniProtKB=W5NNV9 W5NNV9 PTHR24231:SF17 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 2 signaling receptor activity#GO:0038023;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017486.1|UniProtKB=W5NLT2 W5NLT2 PTHR12002:SF185 CLAUDIN CLAUDIN 2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000001570.1|UniProtKB=W5M0A0 W5M0A0 PTHR22968:SF25 PROTEIN KINASE C, MU PROTEIN KINASE C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016164.1|UniProtKB=W5NH08 W5NH08 PTHR24419:SF7 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 3 histone modifying activity#GO:0140993;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of gene expression#GO:0010629;response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;mitotic cell cycle#GO:0000278;response to biotic stimulus#GO:0009607;negative regulation of MAPK cascade#GO:0043409;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;response to molecule of bacterial origin#GO:0002237;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cellular response to biotic stimulus#GO:0071216;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;response to lipopolysaccharide#GO:0032496;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;response to interleukin-1#GO:0070555;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;cellular response to lipopolysaccharide#GO:0071222;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;response to lipid#GO:0033993;regulation of catalytic activity#GO:0050790;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;cellular response to oxygen-containing compound#GO:1901701;positive regulation of NF-kappaB transcription factor activity#GO:0051092;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;negative regulation of phosphorus metabolic process#GO:0010563;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cell cycle#GO:0007049;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAKM#P01378 LEPOC|Ensembl=ENSLOCG00000004023.1|UniProtKB=W5M8U6 W5M8U6 PTHR23333:SF4 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004805.1|UniProtKB=W5MBL0 W5MBL0 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 LEPOC|Ensembl=ENSLOCG00000014356.1|UniProtKB=W5NAL6 W5NAL6 PTHR23043:SF34 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 1 SUBUNIT ALPHA,-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;response to oxygen levels#GO:0070482 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000018120.1|UniProtKB=W5NNL2 W5NNL2 PTHR23266:SF322 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-8 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009964.1|UniProtKB=W5MUX5 W5MUX5 PRPS2 PTHR10210:SF32 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000008367.1|UniProtKB=W5MP54 W5MP54 PTHR28398:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;central element#GO:0000801;synaptonemal complex#GO:0000795 LEPOC|Ensembl=ENSLOCG00000007434.1|UniProtKB=W5MKV7 W5MKV7 TMEM212 PTHR23320:SF130 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED TRANSMEMBRANE PROTEIN 212 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001249.1|UniProtKB=W5LZ61 W5LZ61 PTHR24286:SF177 CYTOCHROME P450 26 CYTOCHROME P450 26B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015179.1|UniProtKB=W5NDG9 W5NDG9 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008633.1|UniProtKB=W5MQ34 W5MQ34 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of gene expression#GO:0010628;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000009226.1|UniProtKB=W5MSB3 W5MSB3 DGKD PTHR11255:SF30 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE DELTA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005895.1|UniProtKB=W5MFG3 W5MFG3 SLC35G1 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018108.1|UniProtKB=W5NNK0 W5NNK0 PTHR28613:SF9 SI:CH211-232M10.4-RELATED TRANSMEMBRANE PROTEIN 238 LEPOC|Ensembl=ENSLOCG00000009011.1|UniProtKB=W5MRH5 W5MRH5 PTHR46920:SF1 FAMILY NOT NAMED PROTEIN MSS51 HOMOLOG, MITOCHONDRIAL-RELATED LEPOC|Ensembl=ENSLOCG00000009507.1|UniProtKB=W5MTB0 W5MTB0 PTHR45683:SF3 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED MITOCHONDRIAL FOLATE TRANSPORTER_CARRIER amide transmembrane transporter activity#GO:0042887;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vitamin transport#GO:0051180;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005334.1|UniProtKB=W5MDG9 W5MDG9 PTHR12369:SF22 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009645.1|UniProtKB=W5MTT1 W5MTT1 PTHR15923:SF3 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 1 cargo receptor activity#GO:0038024 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012310.1|UniProtKB=W5N3D2 W5N3D2 PTHR28596:SF1 BBSOME-INTERACTING PROTEIN 1 BBSOME-INTERACTING PROTEIN 1 localization#GO:0051179;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;BBSome#GO:0034464;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000014440.1|UniProtKB=W5NAW4 W5NAW4 PTHR32267:SF2 T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN LEPOC|Ensembl=ENSLOCG00000011820.1|UniProtKB=W5N1M8 W5N1M8 PTHR43880:SF32 ALCOHOL DEHYDROGENASE S-(HYDROXYMETHYL)GLUTATHIONE DEHYDROGENASE cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;cellular process#GO:0009987;response to stimulus#GO:0050896;detoxification#GO:0098754;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008791.1|UniProtKB=W5MQP4 W5MQP4 CYP4F8 PTHR24291:SF210 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 FAMILY 4 SUBFAMILY F MEMBER 11 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007387.1|UniProtKB=W5MKQ5 W5MKQ5 PTHR47222:SF2 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 687 LEPOC|Ensembl=ENSLOCG00000009864.1|UniProtKB=W5MUJ8 W5MUJ8 PTHR23251:SF0 LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN PROTEIN LYRIC molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000680.1|UniProtKB=W5LXA4 W5LXA4 PTHR46532:SF13 MALE FERTILITY FACTOR KL5 CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000006521.1|UniProtKB=W5MHN2 W5MHN2 PTHR31859:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39C LEPOC|Ensembl=ENSLOCG00000017546.1|UniProtKB=W5NLZ2 W5NLZ2 S1PR3 PTHR22750:SF24 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000792.1|UniProtKB=W5LXP9 W5LXP9 CIBAR2 PTHR21223:SF3 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 2 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006442.1|UniProtKB=W5MHC0 W5MHC0 PTHR18952:SF84 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 14 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000009155.1|UniProtKB=W5MS01 W5MS01 PTHR11304:SF33 EPHRIN EPHRIN-A5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of cell-cell adhesion#GO:0022407;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007599.1|UniProtKB=W5MLG1 W5MLG1 PTHR24255:SF29 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT COMPONENT 1, S SUBCOMPONENT hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002991.1|UniProtKB=W5M571 W5M571 PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011342.1|UniProtKB=W5MZY3 W5MZY3 PTHR14218:SF15 PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2 TRIPEPTIDYL-PEPTIDASE 1 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001013.1|UniProtKB=W5LYD7 W5LYD7 PTHR11949:SF7 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015916.1|UniProtKB=W5NG50 W5NG50 PTHR45653:SF7 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 4 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330;cell chemotaxis#GO:0060326 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016738.1|UniProtKB=W5NJ77 W5NJ77 PTHR17005:SF3 MALE-ENHANCED ANTIGEN-1 MALE-ENHANCED ANTIGEN 1 LEPOC|Ensembl=ENSLOCG00000013673.1|UniProtKB=W5N899 W5N899 PTHR23119:SF33 DISCS LARGE DISKS LARGE HOMOLOG 4 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;membrane organization#GO:0061024;developmental process#GO:0032502;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;cell-cell signaling#GO:0007267;signaling#GO:0023052;postsynapse organization#GO:0099173;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;neuron projection#GO:0043005;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;basal part of cell#GO:0045178;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Huntington disease#P00029>PSD-95#P00789 LEPOC|Ensembl=ENSLOCG00000000656.1|UniProtKB=W5LX66 W5LX66 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013459.1|UniProtKB=W5N7J6 W5N7J6 PTHR24083:SF42 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016194.1|UniProtKB=W5NH52 W5NH52 PTHR21258:SF40 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;growth factor receptor binding#GO:0070851;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;fibroblast growth factor receptor binding#GO:0005104 fibroblast growth factor receptor signaling pathway#GO:0008543;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular response to fibroblast growth factor stimulus#GO:0044344;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>FRS2#P00635;Angiogenesis#P00005>FRS-2#P00240 LEPOC|Ensembl=ENSLOCG00000015018.1|UniProtKB=W5NCX9 W5NCX9 PTHR10501:SF30 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA-BINDING PROTEIN WITH MULTIPLE SPLICING 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011866.1|UniProtKB=W5N1T5 W5N1T5 PTHR22981:SF7 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003367.1|UniProtKB=W5M6H4 W5M6H4 PTHR22909:SF24 GOLGI INTEGRAL MEMBRANE PROTEIN 4 GOLGI INTEGRAL MEMBRANE PROTEIN 4-RELATED cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014991.1|UniProtKB=W5NCU7 W5NCU7 TBX22 PTHR11267:SF116 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX22 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000004565.1|UniProtKB=W5MAS5 W5MAS5 PTHR11530:SF15 D-AMINO ACID OXIDASE D-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001689.1|UniProtKB=W5M0N5 W5M0N5 PTHR28607:SF2 EXPRESSED PROTEIN PROTEIN FAM174C cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000007109.1|UniProtKB=W5MJQ6 W5MJQ6 PTHR23503:SF32 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015793.1|UniProtKB=W5NFN8 W5NFN8 PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004677.1|UniProtKB=W5MB44 W5MB44 PTHR23410:SF12 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016937.1|UniProtKB=W5NJX6 W5NJX6 PNRC1 PTHR15405:SF8 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 1 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004691.1|UniProtKB=W5MB63 W5MB63 KANSL1L PTHR22443:SF16 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1-LIKE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000002766.1|UniProtKB=W5M4E7 W5M4E7 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002174.1|UniProtKB=W5M2D3 W5M2D3 PTHR23512:SF5 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011190.1|UniProtKB=W5MZF5 W5MZF5 PTHR45901:SF3 PROTEIN CBG12474 LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000004595.1|UniProtKB=W5MAU2 W5MAU2 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000000190.1|UniProtKB=W5LVS7 W5LVS7 PTHR23411:SF41 TAPASIN IG KAPPA-B4 CHAIN C REGION immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011509.1|UniProtKB=W5N0I2 W5N0I2 PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008345.1|UniProtKB=W5MP24 W5MP24 PTHR24173:SF23 ANKYRIN REPEAT CONTAINING UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;negative regulation of biological process#GO:0048519;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;negative regulation of signaling#GO:0023057;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006455.1|UniProtKB=W5MHD4 W5MHD4 PTHR15854:SF4 THAP4 PROTEIN PEROXYNITRITE ISOMERASE THAP4 LEPOC|Ensembl=ENSLOCG00000016983.1|UniProtKB=W5NK36 W5NK36 PPM1H PTHR13832:SF838 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1H hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012902.1|UniProtKB=W5N5H6 W5N5H6 BNC1 PTHR15021:SF1 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-1 regulation of transcription by RNA polymerase I#GO:0006356;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005531.1|UniProtKB=W5ME64 W5ME64 IQANK1 PTHR24173:SF74 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017120.1|UniProtKB=W5NKJ8 W5NKJ8 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013327.1|UniProtKB=W5N716 W5N716 PTHR16165:SF23 NXPE FAMILY MEMBER NEUREXOPHILIN AND PC-ESTERASE DOMAIN FAMILY, MEMBER 5 LEPOC|Ensembl=ENSLOCG00000009809.1|UniProtKB=W5MUD0 W5MUD0 NIPAL2 PTHR12570:SF16 FAMILY NOT NAMED NIPA-LIKE PROTEIN 2 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006127.1|UniProtKB=W5MG95 W5MG95 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000007081.1|UniProtKB=W5MJL3 W5MJL3 PTHR16135:SF2 REPRESSOR OF YIELD OF DENV PROTEIN SHIFTLESS ANTIVIRAL INHIBITOR OF RIBOSOMAL FRAMESHIFTING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877 response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response#GO:0006952;defense response to symbiont#GO:0140546 LEPOC|Ensembl=ENSLOCG00000008776.1|UniProtKB=W5MQM2 W5MQM2 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 LEPOC|Ensembl=ENSLOCG00000001960.1|UniProtKB=W5M1L0 W5M1L0 PTHR24103:SF695 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-18P12.4-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001819.1|UniProtKB=W5M148 W5M148 PTHR23050:SF325 CALCIUM BINDING PROTEIN CENTRIN-3 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000013170.1|UniProtKB=W5N6G7 W5N6G7 PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase#PC00079;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000007131.1|UniProtKB=W5MJS6 W5MJS6 PTHR12566:SF7 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;synapse#GO:0045202;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013548.1|UniProtKB=W5N7U8 W5N7U8 PTHR15109:SF2 AGAP004327-PA PROTEIN FAM193A LEPOC|Ensembl=ENSLOCG00000012132.1|UniProtKB=W5N2R3 W5N2R3 PTHR11848:SF165 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 4 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000016929.1|UniProtKB=W5NJW9 W5NJW9 ATP6V0A4 PTHR11629:SF26 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 4 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002350.1|UniProtKB=W5M2Z6 W5M2Z6 PTHR13678:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 SI:CH211-284F22.3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011185.1|UniProtKB=W5MZD0 W5MZD0 PTHR45793:SF2 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013768.1|UniProtKB=W5N8L7 W5N8L7 PTHR10985:SF8 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT-RELATED PROTEIN HELT sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000011950.1|UniProtKB=W5N248 W5N248 PTHR10856:SF2 CORONIN CORONIN-2A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004210.1|UniProtKB=W5M9J7 W5M9J7 PTHR24347:SF386 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, SKELETAL MUSCLE_HEART ISOFORM non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000001157.1|UniProtKB=W5LYU8 W5LYU8 PTHR19957:SF3 SYNTAXIN SYNTAXIN-5 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;SNARE complex#GO:0031201;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000003748.1|UniProtKB=W5M7W1 W5M7W1 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016746.1|UniProtKB=W5NJ86 W5NJ86 PTHR11232:SF81 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PID DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014598.1|UniProtKB=W5NBF6 W5NBF6 PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008707.1|UniProtKB=W5MQD9 W5MQD9 PTHR14880:SF2 PROLINE AND SERINE-RICH PROTEIN 1 PROLINE AND SERINE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001700.1|UniProtKB=W5M0Q7 W5M0Q7 RTEL1 PTHR11472:SF34 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER REGULATOR OF TELOMERE ELONGATION HELICASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014285.1|UniProtKB=W5NAD1 W5NAD1 PTHR15382:SF2 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 3 LEPOC|Ensembl=ENSLOCG00000005553.1|UniProtKB=W5MEA1 W5MEA1 PTHR10117:SF7 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 6 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;fertilization#GO:0009566;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;single fertilization#GO:0007338;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;reproduction#GO:0000003;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;sexual reproduction#GO:0019953;reproductive process#GO:0022414;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000014631.1|UniProtKB=W5NBK0 W5NBK0 PTHR12876:SF27 N4BP1-RELATED RIBONUCLEASE ZC3H12B-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012088.1|UniProtKB=W5N2L2 W5N2L2 PTHR12122:SF5 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006889.1|UniProtKB=W5MIX2 W5MIX2 PTHR45655:SF7 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-2 lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 LEPOC|Ensembl=ENSLOCG00000010700.1|UniProtKB=W5MXJ9 W5MXJ9 PTHR23055:SF60 CALCIUM BINDING PROTEINS CALAXIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009760.1|UniProtKB=W5MU98 W5MU98 VPS13B PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009794.1|UniProtKB=W5MUB2 W5MUB2 PTHR24278:SF35 COAGULATION FACTOR PROTEIN Z, VITAMIN K-DEPENDENT PLASMA GLYCOPROTEIN B extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005502.1|UniProtKB=W5ME37 W5ME37 MCOLN3 PTHR12127:SF5 MUCOLIPIN MUCOLIPIN-3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007366.1|UniProtKB=W5MKP3 W5MKP3 PTHR11902:SF10 ENOLASE GAMMA-ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 lyase#PC00144 Glycolysis#P00024>Enolase#P00678 LEPOC|Ensembl=ENSLOCG00000016992.1|UniProtKB=W5NK46 W5NK46 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of LSU-rRNA#GO:0000470 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011496.1|UniProtKB=W5N0G8 W5N0G8 PTHR24237:SF35 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 141-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006342.1|UniProtKB=W5MH56 W5MH56 PTHR11139:SF9 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE MTOR transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of cellular metabolic process#GO:0031324;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;regulation of macroautophagy#GO:0016241;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of metabolic process#GO:0019222;TOR signaling#GO:0031929;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>TOR#P00817;p53 pathway by glucose deprivation#P04397>mTOR#P04638;Interleukin signaling pathway#P00036>mTOR#P00966;PDGF signaling pathway#P00047>mTOR#P01144 LEPOC|Ensembl=ENSLOCG00000010615.1|UniProtKB=W5MXA5 W5MXA5 PTHR28570:SF3 ASPARTYL AMINOPEPTIDASE ASPARTYL AMINOPEPTIDASE metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002483.1|UniProtKB=W5M3H0 W5M3H0 PTHR11267:SF190 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX20 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000009473.1|UniProtKB=W5MT67 W5MT67 PTHR16036:SF2 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 TRNA ENDONUCLEASE ANKZF1 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000014860.1|UniProtKB=W5NCD7 W5NCD7 PTHR14499:SF30 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING 12B regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277 receptor complex#GO:0043235;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017728.1|UniProtKB=W5NMH3 W5NMH3 PTHR24235:SF15 NEUROPEPTIDE Y RECEPTOR PROLACTIN-RELEASING PEPTIDE RECEPTOR-LIKE PROTEIN 4 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006781.1|UniProtKB=W5MII2 W5MII2 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007623.1|UniProtKB=W5MLI9 W5MLI9 PTHR13610:SF18 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN SI:DKEY-190G11.3 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;peptidyl-amino acid modification#GO:0018193;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;positive regulation of transporter activity#GO:0032411;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009683.1|UniProtKB=W5MTX0 W5MTX0 PTHR22747:SF42 NUCLEOPLASMIN NUCLEOPHOSMIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;ribosomal subunit export from nucleus#GO:0000054;protein-DNA complex organization#GO:0071824;organelle localization#GO:0051640;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;ribosomal large subunit biogenesis#GO:0042273;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;regulation of centrosome duplication#GO:0010824;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of centrosome cycle#GO:0046605;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nuclear export#GO:0051168;protein-containing complex organization#GO:0043933;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;chromatin organization#GO:0006325;intracellular transport#GO:0046907;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;ribosomal small subunit biogenesis#GO:0042274;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014967.1|UniProtKB=W5NCR7 W5NCR7 NUP62 PTHR12084:SF0 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 lipid binding#GO:0008289;structural molecule activity#GO:0005198;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006098.1|UniProtKB=W5MG54 W5MG54 PTHR14759:SF37 STOP PROTEIN MAP6 DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;transport#GO:0006810;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;microtubule cytoskeleton#GO:0015630;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000008623.1|UniProtKB=W5MQ29 W5MQ29 PTHR12011:SF433 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016156.1|UniProtKB=W5NH00 W5NH00 PTHR14002:SF50 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ALPHA-TECTORIN-LIKE-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002448.1|UniProtKB=W5M3B6 W5M3B6 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004262.1|UniProtKB=W5M9P8 W5M9P8 PTHR10582:SF4 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 signal transduction#GO:0007165;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;supramolecular fiber organization#GO:0097435;monoatomic cation transport#GO:0006812;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;cellular response to chemical stimulus#GO:0070887;calcium ion transmembrane transport#GO:0070588;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;calcium ion import#GO:0070509;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;response to osmotic stress#GO:0006970;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;monoatomic ion transport#GO:0006811;cellular response to stress#GO:0033554;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014867.1|UniProtKB=W5NCF0 W5NCF0 PTHR11003:SF264 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 13-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010404.1|UniProtKB=W5MWJ2 W5MWJ2 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;cysteine-type endopeptidase inhibitor activity#GO:0004869;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of proteolysis#GO:0030162;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cysteine-type endopeptidase activity#GO:2000117;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of catalytic activity#GO:0050790;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000000869.1|UniProtKB=W5LXY4 W5LXY4 PTHR44170:SF1 PROTEIN SIDEKICK CELL ADHESION MOLECULE-RELATED_DOWN-REGULATED BY ONCOGENES system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-cell adhesion#GO:0098609;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;nervous system development#GO:0007399;cellular process#GO:0009987 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005666.1|UniProtKB=W5MEM9 W5MEM9 PTHR28309:SF1 REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001559.1|UniProtKB=W5M081 W5M081 PTHR45889:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 presynapse#GO:0098793;synapse#GO:0045202;cell junction#GO:0030054;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000395.1|UniProtKB=W5LWC4 W5LWC4 PTHR21325:SF52 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000012972.1|UniProtKB=W5N5R6 W5N5R6 PTHR45718:SF1 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008192.1|UniProtKB=W5MNI9 W5MNI9 PTHR24221:SF165 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012556.1|UniProtKB=W5N4A0 W5N4A0 PTHR22975:SF6 UBIQUITIN SPECIFIC PROTEINASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 53 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;sensory perception of sound#GO:0007605;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;response to abiotic stimulus#GO:0009628;sensory perception of mechanical stimulus#GO:0050954 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003317.1|UniProtKB=W5M6B4 W5M6B4 PTHR11362:SF147 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN protease inhibitor#PC00191 EGF receptor signaling pathway#P00018>RKIP#P00548 LEPOC|Ensembl=ENSLOCG00000007829.1|UniProtKB=W5MM95 W5MM95 PTHR12943:SF7 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 1 PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;negative regulation of cell communication#GO:0010648;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;intracellular chemical homeostasis#GO:0055082;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;monoatomic ion homeostasis#GO:0050801;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;negative regulation of signal transduction#GO:0009968;intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;negative regulation of programmed cell death#GO:0043069;response to unfolded protein#GO:0006986;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;negative regulation of apoptotic process#GO:0043066;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000015093.1|UniProtKB=W5ND73 W5ND73 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6-LIKE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000005966.1|UniProtKB=W5MFR8 W5MFR8 PTHR24012:SF686 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA splice site recognition#GO:0006376;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012702.1|UniProtKB=W5N4S1 W5N4S1 PTHR47735:SF11 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007755.1|UniProtKB=W5MM06 W5MM06 PTHR21625:SF0 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX SUBUNIT 2 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000001924.1|UniProtKB=W5M1I6 W5M1I6 PTHR11358:SF26 ARGINASE/AGMATINASE GUANIDINO ACID HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011005.1|UniProtKB=W5MYP3 W5MYP3 DONSON PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON cellular aromatic compound metabolic process#GO:0006725;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA metabolic process#GO:0006259;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000756.1|UniProtKB=W5LXI0 W5LXI0 PTHR10824:SF38 ACYL-COENZYME A THIOESTERASE-RELATED ACOT1 THIOESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000007630.1|UniProtKB=W5MLK0 W5MLK0 PTHR23039:SF5 NANCE-HORAN SYNDROME PROTEIN ACTIN REMODELING REGULATOR NHS cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;visual system development#GO:0150063;sensory system development#GO:0048880;cellular process#GO:0009987;sensory organ development#GO:0007423 LEPOC|Ensembl=ENSLOCG00000004430.1|UniProtKB=W5MA91 W5MA91 PTHR46488:SF1 AP-5 COMPLEX SUBUNIT ZETA-1 AP-5 COMPLEX SUBUNIT ZETA-1 LEPOC|Ensembl=ENSLOCG00000015292.1|UniProtKB=W5NDW0 W5NDW0 PTHR23152:SF7 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX COMPONENT E1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 LEPOC|Ensembl=ENSLOCG00000004495.1|UniProtKB=W5MAG6 W5MAG6 PTHR10182:SF11 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39 protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000002774.1|UniProtKB=W5M4G2 W5M4G2 PTHR24412:SF255 KELCH PROTEIN KELCH-LIKE PROTEIN 21 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017665.1|UniProtKB=W5NMB1 W5NMB1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014065.1|UniProtKB=W5N9M2 W5N9M2 PTHR15132:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012831.1|UniProtKB=W5N584 W5N584 PTHR46218:SF2 LASP LIM AND SH3 DOMAIN PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 LEPOC|Ensembl=ENSLOCG00000002908.1|UniProtKB=W5M4X1 W5M4X1 PTHR23347:SF5 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED HARMONIN-BINDING PROTEIN USHBP1 LEPOC|Ensembl=ENSLOCG00000014847.1|UniProtKB=W5NCD2 W5NCD2 PTHR13900:SF0 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011415.1|UniProtKB=W5N073 W5N073 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016837.1|UniProtKB=W5NJK0 W5NJK0 PTHR23235:SF65 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 11 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015397.1|UniProtKB=W5NE91 W5NE91 PTHR10603:SF4 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;RNA localization#GO:0006403;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;RNA transport#GO:0050658;regulation of neuronal synaptic plasticity#GO:0048168;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of multicellular organismal process#GO:0051239;establishment of RNA localization#GO:0051236;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;regulation of trans-synaptic signaling#GO:0099177;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule localization#GO:0033036;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;regulation of amide metabolic process#GO:0034248;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;nucleic acid transport#GO:0050657;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cell communication#GO:0010646;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of nervous system development#GO:0051962;regulation of cellular catabolic process#GO:0031329;mRNA transport#GO:0051028;positive regulation of developmental process#GO:0051094;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cell projection#GO:0042995 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000005542.1|UniProtKB=W5ME81 W5ME81 PTHR12035:SF135 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 13 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012843.1|UniProtKB=W5N597 W5N597 PTHR46374:SF3 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 5 cholesterol transfer activity#GO:0120020;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;transporter activity#GO:0005215;alcohol binding#GO:0043178;lipid transporter activity#GO:0005319;cholesterol binding#GO:0015485 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 LEPOC|Ensembl=ENSLOCG00000003184.1|UniProtKB=W5M5V7 W5M5V7 PTHR23036:SF103 CYTOKINE RECEPTOR GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012531.1|UniProtKB=W5N486 W5N486 PTHR11731:SF20 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6 catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;transporter regulator activity#GO:0141108;peptidase activity#GO:0008233;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;regulation of metal ion transport#GO:0010959;organonitrogen compound metabolic process#GO:1901564;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008714.1|UniProtKB=W5MQE7 W5MQE7 PTHR10026:SF144 CYCLIN CYCLIN-K protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138 Cell cycle#P00013>CdkC#P00489 LEPOC|Ensembl=ENSLOCG00000009439.1|UniProtKB=W5MT11 W5MT11 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000005163.1|UniProtKB=W5MCV8 W5MCV8 PTHR15362:SF13 PHOSPHATIDYLINOSITOL SYNTHASE SI:CH1073-145M9.1 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008637.1|UniProtKB=W5MQ42 W5MQ42 PTHR11818:SF12 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B1 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004514.1|UniProtKB=W5MAK7 W5MAK7 PTHR10926:SF19 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50B organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015274.1|UniProtKB=W5NDT6 W5NDT6 PTHR23430:SF280 HISTONE H2A HISTONE H2A.V nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014223.1|UniProtKB=W5NA57 W5NA57 PTHR14768:SF2 UPF0338 PROTEIN TRANSMEMBRANE PROTEIN 91 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007766.1|UniProtKB=W5MM32 W5MM32 AGO2 PTHR22891:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;pre-miRNA processing#GO:0031054;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;regulatory ncRNA-mediated gene silencing#GO:0031047;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000006745.1|UniProtKB=W5MIE2 W5MIE2 PTHR16306:SF0 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000116.1|UniProtKB=W5LVH3 W5LVH3 GPR88 PTHR24246:SF48 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 88 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007343.1|UniProtKB=W5MKJ1 W5MKJ1 PTHR11034:SF18 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008427.1|UniProtKB=W5MPF4 W5MPF4 PTHR46785:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B LEPOC|Ensembl=ENSLOCG00000011056.1|UniProtKB=W5MYW5 W5MYW5 PTHR11772:SF23 ASPARAGINE SYNTHETASE ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853 LEPOC|Ensembl=ENSLOCG00000005650.1|UniProtKB=W5MEN3 W5MEN3 PTHR13743:SF111 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011135.1|UniProtKB=W5MZ65 W5MZ65 PTHR10164:SF3 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010756.1|UniProtKB=W5MXS4 W5MXS4 CASP8 PTHR10454:SF240 CASPASE CASPASE 20, APOPTOSIS-RELATED CYSTEINE PEPTIDASE-RELATED cysteine-type peptidase activity#GO:0008234;binding#GO:0005488;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;protein binding#GO:0005515;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase8#P00594;Apoptosis signaling pathway#P00006>Caspase 8#P00299;Huntington disease#P00029>Pro-caspase 8#P00767;FAS signaling pathway#P00020>Pro-Caspase8#P00604;Huntington disease#P00029>Caspase 8#P00808 LEPOC|Ensembl=ENSLOCG00000004299.1|UniProtKB=W5M9T0 W5M9T0 PTHR45889:SF3 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 4 growth factor receptor binding#GO:0070851;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of wound healing#GO:0061041;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;negative regulation of phosphorus metabolic process#GO:0010563;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;regulation of response to stress#GO:0080134;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to wounding#GO:1903034;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cell junction#GO:0030054;cell-cell contact zone#GO:0044291;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000014015.1|UniProtKB=W5N9G6 W5N9G6 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000017869.1|UniProtKB=W5NMW3 W5NMW3 PTHR11309:SF79 FRIZZLED FRIZZLED-9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000004706.1|UniProtKB=W5MB82 W5MB82 MAP2 PTHR11501:SF15 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000001286.1|UniProtKB=W5LZ99 W5LZ99 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 GLYCOSYLTRANSFERASE-LIKE DOMAIN-CONTAINING PROTEIN 1 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002117.1|UniProtKB=W5M253 W5M253 PTHR24068:SF116 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN CONJUGATING ENZYME E2 L3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>UbcH7#P01224;Parkinson disease#P00049>UbcH8#P01223;Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000004489.1|UniProtKB=W5MAJ0 W5MAJ0 PTHR21573:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000006771.1|UniProtKB=W5MIH8 W5MIH8 PTHR10504:SF16 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED PHOSPHOLIPID TRANSFER PROTEIN phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;regulation of biological process#GO:0050789;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;lipid localization#GO:0010876 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013260.1|UniProtKB=W5N6S6 W5N6S6 PTHR15907:SF30 DUF614 FAMILY PROTEIN-RELATED CORNIFELIN HOMOLOG B-RELATED LEPOC|Ensembl=ENSLOCG00000018344.1|UniProtKB=W5NP86 W5NP86 PTHR13976:SF83 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA BINDING MOTIF PROTEIN 12B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008492.1|UniProtKB=W5MPM6 W5MPM6 PTHR11214:SF361 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000302.1|UniProtKB=W5LW22 W5LW22 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009926.1|UniProtKB=W5MUS6 W5MUS6 PTHR19446:SF477 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000011255.1|UniProtKB=W5MZM1 W5MZM1 PTHR45710:SF36 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000892.1|UniProtKB=W5LXY3 W5LXY3 PTHR10489:SF944 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8-LIKE signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004422.1|UniProtKB=W5MA73 W5MA73 PTHR24264:SF7 TRYPSIN-RELATED TRYPSIN-2-LIKE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008030.1|UniProtKB=W5MMZ8 W5MMZ8 HDGF PTHR12550:SF41 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015241.1|UniProtKB=W5NDP5 W5NDP5 PTHR13087:SF0 NF-KAPPA B ACTIVATING PROTEIN NFKB ACTIVATING PROTEIN LIKE regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001060.1|UniProtKB=W5LYI8 W5LYI8 PTHR46927:SF1 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 5 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008525.1|UniProtKB=W5MPR5 W5MPR5 PTHR12141:SF4 ARFAPTIN-RELATED ARFAPTIN-1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of actin filament-based process#GO:0032970 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015835.1|UniProtKB=W5NFT6 W5NFT6 PTHR43816:SF3 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008755.1|UniProtKB=W5MQK5 W5MQK5 PTHR22808:SF1 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000017029.1|UniProtKB=W5NK88 W5NK88 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 19P-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017193.1|UniProtKB=W5NKU0 W5NKU0 PTHR24020:SF12 COLLAGEN ALPHA MATRILIN-3 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000016363.1|UniProtKB=W5NHU5 W5NHU5 PTHR16087:SF0 TRANSMEMBRANE PROTEIN 206 PROTON-ACTIVATED CHLORIDE CHANNEL LEPOC|Ensembl=ENSLOCG00000002352.1|UniProtKB=W5M2Z5 W5M2Z5 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014745.1|UniProtKB=W5NBZ3 W5NBZ3 PTHR24228:SF56 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN-RELATED RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000002145.1|UniProtKB=W5M288 W5M288 PTHR13388:SF7 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132E LEPOC|Ensembl=ENSLOCG00000016659.1|UniProtKB=W5NIX0 W5NIX0 PTHR12126:SF11 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011107.1|UniProtKB=W5MZ46 W5MZ46 PTHR21812:SF1 INO80 COMPLEX SUBUNIT E INO80 COMPLEX SUBUNIT E membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;cellular anatomical entity#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005014.1|UniProtKB=W5MCC8 W5MCC8 PTHR21257:SF38 DELTA(14)-STEROL REDUCTASE 7-DEHYDROCHOLESTEROL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;phytosteroid metabolic process#GO:0016128;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005085.1|UniProtKB=W5MCL4 W5MCL4 PTHR11820:SF7 ACYLPYRUVASE ACYLPYRUVASE FAHD1, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015123.1|UniProtKB=W5NDA3 W5NDA3 PTHR12241:SF161 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL6 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015042.1|UniProtKB=W5ND11 W5ND11 PTHR23063:SF37 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000005388.1|UniProtKB=W5MDN9 W5MDN9 PTHR45616:SF9 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8-RELATED structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;skin development#GO:0043588;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;epidermis development#GO:0008544;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;intermediate filament organization#GO:0045109;multicellular organismal process#GO:0032501;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;extracellular region#GO:0005576;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;extracellular space#GO:0005615;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;keratin filament#GO:0045095;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000008539.1|UniProtKB=W5MPT1 W5MPT1 PTHR10900:SF12 PERIOSTIN-RELATED PERIOSTIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005682.1|UniProtKB=W5MEQ1 W5MEQ1 PTHR21600:SF87 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015151.1|UniProtKB=W5NDE5 W5NDE5 PTHR24355:SF26 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005908.1|UniProtKB=W5MFH4 W5MFH4 PTHR46550:SF1 F-BOX ONLY PROTEIN 3 F-BOX PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013369.1|UniProtKB=W5N766 W5N766 FBXO24 PTHR47004:SF1 F-BOX ONLY PROTEIN 24 F-BOX ONLY PROTEIN 24 LEPOC|Ensembl=ENSLOCG00000006430.1|UniProtKB=W5MHE8 W5MHE8 PTHR45628:SF3 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT P_Q-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1A calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655;signaling#GO:0023052;import into cell#GO:0098657 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;GABA-B receptor II signaling#P05731>Ca channel#P05753;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 LEPOC|Ensembl=ENSLOCG00000012860.1|UniProtKB=W5N5D4 W5N5D4 PLCB2 PTHR10336:SF10 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Endogenous cannabinoid signaling#P05730>PLC#P05746;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 LEPOC|Ensembl=ENSLOCG00000012521.1|UniProtKB=W5N466 W5N466 PTHR11537:SF40 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014417.1|UniProtKB=W5NAT6 W5NAT6 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000006858.1|UniProtKB=W5MIT8 W5MIT8 PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000015454.1|UniProtKB=W5NEG6 W5NEG6 PTHR11675:SF49 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007870.1|UniProtKB=W5MME5 W5MME5 PTHR10872:SF1 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 3 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014243.1|UniProtKB=W5NA81 W5NA81 RASGRP4 PTHR23113:SF157 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 4 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 LEPOC|Ensembl=ENSLOCG00000012080.1|UniProtKB=W5N2L1 W5N2L1 PTHR24169:SF9 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;B cell activation#P00010>NFkappaB#P00370;T cell activation#P00053>NFkappaB#P01298;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 LEPOC|Ensembl=ENSLOCG00000014017.1|UniProtKB=W5N9H0 W5N9H0 PTHR33667:SF7 SI:DKEY-57N24.6 RIKEN CDNA 1810020O05 GENE LEPOC|Ensembl=ENSLOCG00000017417.1|UniProtKB=W5NLL3 W5NLL3 STX19 PTHR19957:SF29 SYNTAXIN SYNTAXIN-19 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000017845.1|UniProtKB=W5NMT9 W5NMT9 PTHR24230:SF123 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006310.1|UniProtKB=W5MGW0 W5MGW0 PTHR19139:SF34 AQUAPORIN TRANSPORTER AQUAPORIN-4 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001146.1|UniProtKB=W5LYU0 W5LYU0 PTHR13618:SF1 LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1 PROTEIN ROGDI HOMOLOG cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000014112.1|UniProtKB=W5N9S7 W5N9S7 PTHR48190:SF2 PROGRAMMED CELL DEATH PROTEIN 7 PROGRAMMED CELL DEATH PROTEIN 7 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013044.1|UniProtKB=W5N621 W5N621 UNC79 PTHR21696:SF2 PROTEIN UNC-79 HOMOLOG PROTEIN UNC-79 HOMOLOG LEPOC|Ensembl=ENSLOCG00000008360.1|UniProtKB=W5MP46 W5MP46 OTOA PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001968.1|UniProtKB=W5M1L9 W5M1L9 PTHR45921:SF3 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003755.1|UniProtKB=W5M7Z5 W5M7Z5 PTHR11216:SF69 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15-LIKE 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;plasma membrane protein complex#GO:0098797;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;clathrin-coated pit#GO:0005905;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006230.1|UniProtKB=W5MGN8 W5MGN8 PTHR24271:SF80 KALLIKREIN-RELATED GRANZYME 3, TANDEM DUPLICATE 1-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002222.1|UniProtKB=W5M2H8 W5M2H8 PTHR21446:SF12 DUF3504 DOMAIN-CONTAINING PROTEIN POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000013651.1|UniProtKB=W5N875 W5N875 PTHR10177:SF184 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B2 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000005420.1|UniProtKB=W5MDS7 W5MDS7 PTHR12840:SF1 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007741.1|UniProtKB=W5MLY7 W5MLY7 PTHR23248:SF58 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016411.1|UniProtKB=W5NI11 W5NI11 PTHR22950:SF222 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001386.1|UniProtKB=W5LZN5 W5LZN5 PTHR42884:SF14 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 serine protease#PC00203;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000000754.1|UniProtKB=W5LXH7 W5LXH7 PTHR23411:SF41 TAPASIN IG KAPPA-B4 CHAIN C REGION immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007380.1|UniProtKB=W5MKP0 W5MKP0 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;TORC2 signaling#GO:0038203;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of neuronal synaptic plasticity#GO:0048168;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011843.1|UniProtKB=W5N1Q2 W5N1Q2 PTHR24229:SF85 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009839.1|UniProtKB=W5MUI3 W5MUI3 PTHR11506:SF27 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008893.1|UniProtKB=W5MR25 W5MR25 PTHR12436:SF3 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;transcription export complex 2#GO:0070390;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011191.1|UniProtKB=W5MZE2 W5MZE2 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;endoribonuclease complex#GO:1902555;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016598.1|UniProtKB=W5NIP2 W5NIP2 PTHR12358:SF31 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012191.1|UniProtKB=W5N2Y2 W5N2Y2 PTHR11818:SF107 BETA/GAMMA CRYSTALLIN CRYGMX PROTEIN structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005373.1|UniProtKB=W5MDM2 W5MDM2 PTHR24322:SF747 PKSB EPIDERMAL RETINAL DEHYDROGENASE 2-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017811.1|UniProtKB=W5NMQ6 W5NMQ6 PTHR14388:SF18 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SOCS BOX DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010645.1|UniProtKB=W5MXD2 W5MXD2 PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 LEPOC|Ensembl=ENSLOCG00000000251.1|UniProtKB=W5LVW8 W5LVW8 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003891.1|UniProtKB=W5M8D4 W5M8D4 NACC2 PTHR46105:SF2 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012042.1|UniProtKB=W5N2F3 W5N2F3 PTHR47729:SF1 SERINE PEPTIDASE INHIBITOR, KAZAL TYPE 2, TANDEM DUPLICATE 1-RELATED OVOMUCOID-LIKE-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003621.1|UniProtKB=W5M7E1 W5M7E1 PTHR46551:SF1 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007987.1|UniProtKB=W5MMT9 W5MMT9 PTHR28663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 173 CILIA- AND FLAGELLA- ASSOCIATED PROTEIN 210 LEPOC|Ensembl=ENSLOCG00000003543.1|UniProtKB=W5M740 W5M740 PTHR24184:SF6 SI:CH211-189E2.2 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000017005.1|UniProtKB=W5NK59 W5NK59 KATNA1 PTHR23074:SF71 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000864.1|UniProtKB=W5LXV6 W5LXV6 COQ4 PTHR12922:SF7 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000001677.1|UniProtKB=W5M0M4 W5M0M4 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013844.1|UniProtKB=W5N8X1 W5N8X1 PTHR10183:SF381 CALPAIN CALPAIN-6 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000008108.1|UniProtKB=W5MN88 W5MN88 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012114.1|UniProtKB=W5N2P5 W5N2P5 PTHR45682:SF1 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000014021.1|UniProtKB=W5N9H4 W5N9H4 PTHR15382:SF3 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 4 LEPOC|Ensembl=ENSLOCG00000013413.1|UniProtKB=W5N7C8 W5N7C8 PTHR12990:SF10 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009834.1|UniProtKB=W5MUG0 W5MUG0 PTHR33488:SF2 ZGC:162509 EARLY ENDOSOME ANTIGEN 1-LIKE LEPOC|Ensembl=ENSLOCG00000004005.1|UniProtKB=W5M8R8 W5M8R8 PTHR12487:SF6 TEASHIRT-RELATED TEASHIRT HOMOLOG 1 nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010138.1|UniProtKB=W5MVJ6 W5MVJ6 PTHR11588:SF494 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001045.1|UniProtKB=W5LYG7 W5LYG7 PTHR11375:SF1 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001282.1|UniProtKB=W5LZ91 W5LZ91 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004306.1|UniProtKB=W5M9T9 W5M9T9 PTHR10867:SF32 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 LEPOC|Ensembl=ENSLOCG00000016089.1|UniProtKB=W5NGR2 W5NGR2 PTHR21206:SF0 SLD5 PROTEIN DNA REPLICATION COMPLEX GINS PROTEIN SLD5 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000000316.1|UniProtKB=W5LW43 W5LW43 PTHR14063:SF5 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG C protein binding#GO:0005515;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 membrane protein complex#GO:0098796;synapse#GO:0045202;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal plasma membrane#GO:0009925;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;adherens junction#GO:0005912;basal part of cell#GO:0045178;plasma membrane#GO:0005886 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000002689.1|UniProtKB=W5M462 W5M462 ATP2C2 PTHR42861:SF23 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003778.1|UniProtKB=W5M803 W5M803 GFM1 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 LEPOC|Ensembl=ENSLOCG00000014513.1|UniProtKB=W5NB59 W5NB59 PTHR12756:SF5 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 4 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015402.1|UniProtKB=W5NE96 W5NE96 CATSPERE PTHR33722:SF3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT EPSILON sperm capacitation#GO:0048240;germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cilium-dependent cell motility#GO:0060285;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;sperm flagellum#GO:0036126;voltage-gated calcium channel complex#GO:0005891;sperm principal piece#GO:0097228;CatSper complex#GO:0036128;motile cilium#GO:0031514;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;9+2 motile cilium#GO:0097729;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000005054.1|UniProtKB=W5MCH5 W5MCH5 PTHR24418:SF224 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FGR protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230 LEPOC|Ensembl=ENSLOCG00000003678.1|UniProtKB=W5M7K7 W5M7K7 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001872.1|UniProtKB=W5M1A8 W5M1A8 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000007396.1|UniProtKB=W5MKT0 W5MKT0 PTHR23086:SF54 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000016102.1|UniProtKB=W5NGS9 W5NGS9 PTHR45752:SF169 LEUCINE-RICH REPEAT-CONTAINING NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000416.1|UniProtKB=W5LWF3 W5LWF3 PTHR16675:SF191 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, F10 ALPHA CHAIN-LIKE-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000004621.1|UniProtKB=W5MAX8 W5MAX8 PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83A-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000014438.1|UniProtKB=W5NAW2 W5NAW2 PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;contractile actin filament bundle assembly#GO:0030038;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;stress fiber assembly#GO:0043149;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;Rho protein signal transduction#GO:0007266;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cytosol#GO:0005829;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell division site#GO:0032153;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;CCKR signaling map#P06959>RHOA-GTP#P07188;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GDP#P07019;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254 LEPOC|Ensembl=ENSLOCG00000005284.1|UniProtKB=W5MDA5 W5MDA5 PTHR12788:SF4 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 peptidyl-tyrosine modification#GO:0018212;sulfur compound metabolic process#GO:0006790;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CCKR signaling map#P06959>Protein tyrosine sulfotransferase#P07148 LEPOC|Ensembl=ENSLOCG00000003843.1|UniProtKB=W5M877 W5M877 PTHR13282:SF6 PROTEIN FAM32A PROTEIN FAM32A intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005296.1|UniProtKB=W5MDB9 W5MDB9 PTHR12478:SF7 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;negative regulation of signal transduction#GO:0009968;response to abiotic stimulus#GO:0009628;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;response to oxygen levels#GO:0070482 LEPOC|Ensembl=ENSLOCG00000003784.1|UniProtKB=W5M814 W5M814 PTHR46734:SF1 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR 1 LEPOC|Ensembl=ENSLOCG00000017279.1|UniProtKB=W5NL64 W5NL64 PTHR14963:SF6 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 18 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of signaling#GO:0023051;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of supramolecular fiber organization#GO:1902903;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005110.1|UniProtKB=W5MCP2 W5MCP2 PTHR11935:SF80 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000924.1|UniProtKB=W5LY23 W5LY23 PTHR11216:SF127 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;plasma membrane bounded cell projection organization#GO:0120036;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization#GO:0008104;organelle assembly#GO:0070925;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009173.1|UniProtKB=W5MS29 W5MS29 PTHR28630:SF3 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2C LEPOC|Ensembl=ENSLOCG00000008852.1|UniProtKB=W5MQV8 W5MQV8 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;U6 snRNP#GO:0005688;organelle lumen#GO:0043233;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011592.1|UniProtKB=W5N0T0 W5N0T0 PTHR21043:SF0 IOJAP SUPERFAMILY ORTHOLOG MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000018349.1|UniProtKB=W5NP91 W5NP91 PTHR11711:SF139 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000017196.1|UniProtKB=W5NKU6 W5NKU6 PTHR12537:SF52 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005402.1|UniProtKB=W5MDQ4 W5MDQ4 PTHR24390:SF211 ZINC FINGER PROTEIN PLAG1 ZINC FINGER sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003315.1|UniProtKB=W5M6B0 W5M6B0 PTHR28457:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 119 LEPOC|Ensembl=ENSLOCG00000009697.1|UniProtKB=W5MTY6 W5MTY6 PTHR15136:SF2 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 2 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;ion binding#GO:0043167 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of metal ion transport#GO:0010959;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;regulation of calcium ion transport#GO:0051924;positive regulation of transport#GO:0051050;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012268.1|UniProtKB=W5N387 W5N387 PTHR48482:SF3 INTERLEUKIN-19-RELATED INTERLEUKIN-19 LEPOC|Ensembl=ENSLOCG00000011071.1|UniProtKB=W5MYZ8 W5MYZ8 PTHR11106:SF72 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004349.1|UniProtKB=W5M9Y9 W5M9Y9 PTHR45810:SF17 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008453.1|UniProtKB=W5MPH4 W5MPH4 PTHR10902:SF0 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006143.1|UniProtKB=W5MGB2 W5MGB2 PTHR13809:SF50 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001735.1|UniProtKB=W5M0U6 W5M0U6 PTHR11214:SF234 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001790.1|UniProtKB=W5M119 W5M119 PTHR11348:SF22 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 5 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000004203.1|UniProtKB=W5M9G7 W5M9G7 PTHR24115:SF549 KINESIN-RELATED KINESIN-LIKE PROTEIN pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002271.1|UniProtKB=W5M2R1 W5M2R1 PTHR46130:SF1 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000006319.1|UniProtKB=W5MGX1 W5MGX1 PTHR15591:SF11 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003541.1|UniProtKB=W5M729 W5M729 ASB17 PTHR20966:SF2 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000000567.1|UniProtKB=W5LWX0 W5LWX0 PTHR45944:SF1 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009467.1|UniProtKB=W5MT49 W5MT49 PTHR24248:SF17 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000001140.1|UniProtKB=W5LYT2 W5LYT2 DQX1 PTHR18934:SF108 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DQX1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010147.1|UniProtKB=W5MVL0 W5MVL0 S100P PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000013941.1|UniProtKB=W5N984 W5N984 PTHR10841:SF20 SYNAPSIN SYNAPSIN-2 neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;signal release#GO:0023061;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;export from cell#GO:0140352;secretion by cell#GO:0032940 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 LEPOC|Ensembl=ENSLOCG00000007594.1|UniProtKB=W5MLH2 W5MLH2 PTHR24345:SF44 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004310.1|UniProtKB=W5M9U3 W5M9U3 FLT3 PTHR24416:SF356 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to cytokine#GO:0034097;mononuclear cell differentiation#GO:1903131;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;hemopoiesis#GO:0030097;B cell activation#GO:0042113;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;B cell differentiation#GO:0030183;lymphocyte differentiation#GO:0030098;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;cellular response to cytokine stimulus#GO:0071345;leukocyte differentiation#GO:0002521;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012616.1|UniProtKB=W5N4H4 W5N4H4 PTHR22834:SF17 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 38 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017805.1|UniProtKB=W5NMQ0 W5NMQ0 PTHR11984:SF46 CONNEXIN GAP JUNCTION BETA-2 PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000000903.1|UniProtKB=W5LXZ6 W5LXZ6 PTHR11782:SF31 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 8 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000017004.1|UniProtKB=W5NK58 W5NK58 GINM1 PTHR28549:SF1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012870.1|UniProtKB=W5N5C9 W5N5C9 PTHR46018:SF2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013276.1|UniProtKB=W5N6U8 W5N6U8 PTHR13194:SF18 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;protein-containing complex assembly#GO:0065003;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;mitochondrion organization#GO:0007005;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010265.1|UniProtKB=W5MW21 W5MW21 PTHR45679:SF4 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ALPHA-1,2-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001004.1|UniProtKB=W5LYC9 W5LYC9 PTHR47827:SF4 AHD DOMAIN-CONTAINING PROTEIN PROTEIN ENL protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002910.1|UniProtKB=W5M4V9 W5M4V9 PTHR13392:SF5 ATAXIN 1 ATAXIN-1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011194.1|UniProtKB=W5MZE0 W5MZE0 PTHR17530:SF2 PRO-THYROTROPIN-RELEASING HORMONE PRO-THYROTROPIN-RELEASING HORMONE peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586 LEPOC|Ensembl=ENSLOCG00000009441.1|UniProtKB=W5MT30 W5MT30 PTHR11610:SF12 LIPASE LIPASE MEMBER H hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 LEPOC|Ensembl=ENSLOCG00000013574.1|UniProtKB=W5N7Y5 W5N7Y5 PTHR11699:SF102 ALDEHYDE DEHYDROGENASE-RELATED RETINAL DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000006522.1|UniProtKB=W5MHL9 W5MHL9 PTHR45632:SF5 LD33804P KELCH-LIKE PROTEIN 22 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007058.1|UniProtKB=W5MJI4 W5MJI4 PTHR24246:SF47 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000008442.1|UniProtKB=W5MPF7 W5MPF7 PTHR14917:SF4 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 SPERMATOGENESIS-ASSOCIATED 7 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000003592.1|UniProtKB=W5M799 W5M799 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000002929.1|UniProtKB=W5M4Z0 W5M4Z0 PTHR15073:SF2 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 1 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010792.1|UniProtKB=W5MXW8 W5MXW8 PTHR13710:SF120 DNA HELICASE RECQ FAMILY MEMBER BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 p53 pathway#P00059>WRN#P04617 LEPOC|Ensembl=ENSLOCG00000008639.1|UniProtKB=W5MQ39 W5MQ39 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001177.1|UniProtKB=W5LYW6 W5LYW6 PTHR10258:SF4 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-3 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ligand-gated monoatomic cation channel activity#GO:0099094;channel regulator activity#GO:0016247;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014327.1|UniProtKB=W5NAI7 W5NAI7 PTHR11822:SF21 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015351.1|UniProtKB=W5NE32 W5NE32 PTHR22730:SF6 PROMININ PROM PROTEIN PROMININ-2 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 microvillus#GO:0005902;extracellular region#GO:0005576;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;cell surface#GO:0009986;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002319.1|UniProtKB=W5M2V7 W5M2V7 PTHR14308:SF0 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000015059.1|UniProtKB=W5ND25 W5ND25 PTHR10015:SF457 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1-LIKE DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000009051.1|UniProtKB=W5MRM4 W5MRM4 PTHR10910:SF58 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1 nucleic acid binding#GO:0003676;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;RNA binding#GO:0003723;tRNA-specific adenosine deaminase activity#GO:0008251;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;adenosine to inosine editing#GO:0006382;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017089.1|UniProtKB=W5NKF8 W5NKF8 PTHR24006:SF858 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018357.1|UniProtKB=W5NP99 W5NP99 PTHR22750:SF4 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 3 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009036.1|UniProtKB=W5MRK3 W5MRK3 PTHR11588:SF61 TUBULIN TUBULIN BETA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 LEPOC|Ensembl=ENSLOCG00000016455.1|UniProtKB=W5NI67 W5NI67 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008028.1|UniProtKB=W5MMZ3 W5MMZ3 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014303.1|UniProtKB=W5NAF3 W5NAF3 PTHR14327:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT GAMMA membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017667.1|UniProtKB=W5NMB3 W5NMB3 PTHR23226:SF240 ZINC FINGER AND SCAN DOMAIN-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001281.1|UniProtKB=W5LZC6 W5LZC6 PTHR21224:SF1 INTEGRATOR COMPLEX SUBUNIT 1 INTEGRATOR COMPLEX SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 LEPOC|Ensembl=ENSLOCG00000017093.1|UniProtKB=W5NKG8 W5NKG8 PTHR12482:SF40 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135A lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000015480.1|UniProtKB=W5NEJ3 W5NEJ3 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000013422.1|UniProtKB=W5N7E1 W5N7E1 RIGI PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014928.1|UniProtKB=W5NCM6 W5NCM6 PTHR18934:SF221 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000018316.1|UniProtKB=W5NP58 W5NP58 PTHR24365:SF522 TOLL-LIKE RECEPTOR LOW QUALITY PROTEIN: TOLL-LIKE RECEPTOR 13-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010891.1|UniProtKB=W5MY98 W5MY98 PTHR13533:SF1 N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000010720.1|UniProtKB=W5MXM7 W5MXM7 PTHR43377:SF1 BILIVERDIN REDUCTASE A BILIVERDIN REDUCTASE A dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012109.1|UniProtKB=W5N2N6 W5N2N6 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005233.1|UniProtKB=W5MD68 W5MD68 PTHR11361:SF122 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH3 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001992.1|UniProtKB=W5M1P3 W5M1P3 PTHR23055:SF57 CALCIUM BINDING PROTEINS NEURON-SPECIFIC CALCIUM-BINDING PROTEIN HIPPOCALCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001885.1|UniProtKB=W5M1C8 W5M1C8 PTHR13946:SF16 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase II activity#GO:0001055 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000002814.1|UniProtKB=W5M4K3 W5M4K3 PTHR45762:SF1 ZINC FINGER RNA-BINDING PROTEIN SPERMATID PERINUCLEAR RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015799.1|UniProtKB=W5NFP0 W5NFP0 PTHR12027:SF70 WNT RELATED PROTEIN WNT-16 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000018206.1|UniProtKB=W5NNU8 W5NNU8 PTHR23516:SF1 SAM (S-ADENOSYL METHIONINE) TRANSPORTER MOLYBDATE-ANION TRANSPORTER cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003385.1|UniProtKB=W5M6J8 W5M6J8 PTHR13107:SF0 N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;mRNA modification#GO:0016556;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004966.1|UniProtKB=W5MC60 W5MC60 PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017870.1|UniProtKB=W5NMW4 W5NMW4 PTHR24399:SF14 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011851.1|UniProtKB=W5N1S4 W5N1S4 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED PAT COMPLEX SUBUNIT CCDC47 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014712.1|UniProtKB=W5NBV3 W5NBV3 PTHR15819:SF8 TRANSMEMBRANE PROTEIN FAM155 NALCN CHANNEL AUXILIARY FACTOR 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006554.1|UniProtKB=W5MHV8 W5MHV8 PTHR24115:SF361 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1A cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;transport along microtubule#GO:0010970;localization#GO:0051179;axo-dendritic transport#GO:0008088;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014125.1|UniProtKB=W5N9U4 W5N9U4 PTHR15454:SF73 NISCHARIN RELATED DYNEIN AXONEMAL LIGHT CHAIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005057.1|UniProtKB=W5MCI0 W5MCI0 PTHR11618:SF77 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;acyltransferase activity#GO:0016746;binding#GO:0005488;catalytic activity#GO:0003824;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;TBP-class protein binding#GO:0017025;protein binding#GO:0005515 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;protein modification process#GO:0036211;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;protein acetylation#GO:0006473;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 LEPOC|Ensembl=ENSLOCG00000007494.1|UniProtKB=W5ML42 W5ML42 PTHR22590:SF4 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN LEPOC|Ensembl=ENSLOCG00000009849.1|UniProtKB=W5MUI4 W5MUI4 PTHR47980:SF22 LD44762P RAS-RELATED PROTEIN RAB-3B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012988.1|UniProtKB=W5N5T6 W5N5T6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5-RELATED cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007554.1|UniProtKB=W5MLA5 W5MLA5 PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006374.1|UniProtKB=W5MH33 W5MH33 PTHR12122:SF5 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013653.1|UniProtKB=W5N882 W5N882 PTHR15751:SF14 TRAFFICKING KINESIN-BINDING PROTEIN HUNTINGTIN-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;signal transduction#GO:0007165;neurogenesis#GO:0022008;organelle localization#GO:0051640;macromolecule localization#GO:0033036;response to growth factor#GO:0070848;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;nervous system development#GO:0007399;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;response to endogenous stimulus#GO:0009719;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;mitochondrion organization#GO:0007005;establishment of organelle localization#GO:0051656;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;protein targeting#GO:0006605;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;mitochondrion#GO:0005739;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995 membrane traffic protein#PC00150 Huntington disease#P00029>HAP1#P00762 LEPOC|Ensembl=ENSLOCG00000015646.1|UniProtKB=W5NF61 W5NF61 PTHR10183:SF395 CALPAIN CALPAIN 2, (M_II) LARGE SUBUNIT A-RELATED cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006570.1|UniProtKB=W5MHS1 W5MHS1 PTHR31266:SF2 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A LEPOC|Ensembl=ENSLOCG00000003406.1|UniProtKB=W5M6M7 W5M6M7 PTHR24377:SF929 IP01015P-RELATED ZINC FINGER PROTEIN 665 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010971.1|UniProtKB=W5MYJ7 W5MYJ7 WFIKKN2 PTHR45938:SF7 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 2 transforming growth factor beta binding#GO:0050431;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000006614.1|UniProtKB=W5MHY9 W5MHY9 PTHR15254:SF2 FANCONI ANEMIA GROUP G PROTEIN FAMILY MEMBER FANCONI ANEMIA GROUP G PROTEIN response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013993.1|UniProtKB=W5N9E2 W5N9E2 PTHR23327:SF4 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007341.1|UniProtKB=W5MKI7 W5MKI7 PTHR10536:SF0 DNA PRIMASE SMALL SUBUNIT DNA PRIMASE SMALL SUBUNIT catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 primase#PC00189 DNA replication#P00017>Primase#P00528 LEPOC|Ensembl=ENSLOCG00000000642.1|UniProtKB=W5LX52 W5LX52 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000017416.1|UniProtKB=W5NLL2 W5NLL2 CLDN14 PTHR12002:SF99 CLAUDIN CLAUDIN-14 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000006068.1|UniProtKB=W5MG23 W5MG23 PTHR10383:SF16 SERINE INCORPORATOR SERINE INCORPORATOR 5 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014862.1|UniProtKB=W5NCE2 W5NCE2 PTHR11848:SF246 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 16 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000002246.1|UniProtKB=W5M2K9 W5M2K9 SCRT2 PTHR24388:SF48 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011735.1|UniProtKB=W5N1B6 W5N1B6 CKS2 PTHR23415:SF48 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;ubiquitin-like protein binding#GO:0032182;protein serine/threonine kinase activator activity#GO:0043539;ubiquitin binding#GO:0043130;protein binding#GO:0005515;protein kinase binding#GO:0019901 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cellular process#GO:0050794 SCF ubiquitin ligase complex#GO:0019005;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013724.1|UniProtKB=W5N8G5 W5N8G5 PTHR34441:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000719.1|UniProtKB=W5LXH3 W5LXH3 PTHR23403:SF1 TREHALASE TREHALASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000001448.1|UniProtKB=W5LZT9 W5LZT9 PTHR15836:SF4 PERIPHILIN 1 PERIPHILIN-1 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;cellular localization#GO:0051641;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;protein localization#GO:0008104;epigenetic regulation of gene expression#GO:0040029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004837.1|UniProtKB=W5MBT3 W5MBT3 PTHR45615:SF13 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIA microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000000603.1|UniProtKB=W5LX05 W5LX05 PTHR46708:SF7 TENASCIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;cell-substrate junction assembly#GO:0007044;system development#GO:0048731;cell-matrix adhesion#GO:0007160;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002031.1|UniProtKB=W5M1U3 W5M1U3 PTHR23055:SF84 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000000558.1|UniProtKB=W5LWV9 W5LWV9 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006765.1|UniProtKB=W5MII5 W5MII5 PTHR24396:SF22 ZINC FINGER PROTEIN PROTEIN WIZ sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013318.1|UniProtKB=W5N705 W5N705 PTHR22780:SF13 ADAPTIN, ALPHA/GAMMA/EPSILON AP-4 COMPLEX SUBUNIT EPSILON-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;membrane coat#GO:0030117;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;membrane#GO:0016020;AP-type membrane coat adaptor complex#GO:0030119;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004192.1|UniProtKB=W5M9E9 W5M9E9 PTHR18881:SF2 POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1-RELATED POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;sperm flagellum#GO:0036126 LEPOC|Ensembl=ENSLOCG00000000229.1|UniProtKB=W5LVU5 W5LVU5 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005750.1|UniProtKB=W5MEY5 W5MEY5 PTHR24390:SF159 ZINC FINGER PROTEIN GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTIONAL REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007470.1|UniProtKB=W5ML10 W5ML10 GALNT6 PTHR11675:SF137 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005991.1|UniProtKB=W5MFT5 W5MFT5 PTHR12183:SF6 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000004209.1|UniProtKB=W5M9H8 W5M9H8 PTHR10217:SF641 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 3 ISOFORM X1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002308.1|UniProtKB=W5M2U3 W5M2U3 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Ubc6#P01222 LEPOC|Ensembl=ENSLOCG00000010555.1|UniProtKB=W5MX26 W5MX26 PTHR23119:SF46 DISCS LARGE ERBB2 INTERACTING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 endosomal transport#GO:0016197;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;plasma membrane region#GO:0098590;postsynapse#GO:0098794;adherens junction#GO:0005912;basal part of cell#GO:0045178;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012185.1|UniProtKB=W5N2X5 W5N2X5 SHISA6 PTHR31774:SF0 PROTEIN SHISA-9-RELATED PROTEIN SHISA-6 regulation of cell communication#GO:0010646;regulation of transmembrane transport#GO:0034762;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of neuronal synaptic plasticity#GO:0048168;regulation of transporter activity#GO:0032409 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane signaling receptor complex#GO:0098802;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;cell projection membrane#GO:0031253;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014639.1|UniProtKB=W5NBL0 W5NBL0 PTHR14773:SF0 WD REPEAT-CONTAINING PROTEIN 76 WD REPEAT-CONTAINING PROTEIN 76 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular response to stress#GO:0080135;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of cell cycle phase transition#GO:1901987;regulation of response to stress#GO:0080134;regulation of cell cycle#GO:0051726;regulation of intracellular signal transduction#GO:1902531;regulation of cell cycle process#GO:0010564 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010232.1|UniProtKB=W5MVX1 W5MVX1 PTHR14969:SF45 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000641.1|UniProtKB=W5LX56 W5LX56 PTHR46117:SF1 FI24210P1 UPSTREAM STIMULATORY FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000000428.1|UniProtKB=W5LWJ0 W5LWJ0 PTHR12623:SF11 NGFI-A BINDING PROTEIN PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1-LIKE molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016975.1|UniProtKB=W5NK28 W5NK28 PTHR14166:SF15 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of locomotion#GO:0040013;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 Axon guidance mediated by Slit/Robo#P00008>SrGAP#P00350;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000009638.1|UniProtKB=W5MTS1 W5MTS1 PTHR24299:SF56 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000040.1|UniProtKB=W5LV89 W5LV89 PTHR45893:SF1 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 5 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007579.1|UniProtKB=W5MLD7 W5MLD7 PTHR24247:SF236 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 6 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;synaptic signaling#GO:0099536;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000007948.1|UniProtKB=W5MMQ1 W5MMQ1 PTHR45720:SF3 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN CLC-KB voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003093.1|UniProtKB=W5M5J6 W5M5J6 PTHR22715:SF0 TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1 TRANSFORMING GROWTH FACTOR BETA REGULATOR 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000018099.1|UniProtKB=W5NNJ1 W5NNJ1 PTHR24226:SF3 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G-PROTEIN COUPLED RECEPTOR 146-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016763.1|UniProtKB=W5NJB5 W5NJB5 PTHR12277:SF61 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN LYSOPHOSPHATIDYLSERINE LIPASE ABHD12 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001112.1|UniProtKB=W5LYP8 W5LYP8 PTHR24346:SF90 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SNF RELATED KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012826.1|UniProtKB=W5N580 W5N580 CDH12 PTHR24027:SF96 CADHERIN-23 CADHERIN-12 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000001863.1|UniProtKB=W5M199 W5M199 PTHR24253:SF70 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 5 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001331.1|UniProtKB=W5LZF2 W5LZF2 PTHR23266:SF390 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010093.1|UniProtKB=W5MVE0 W5MVE0 SIX4 PTHR10390:SF64 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX4-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000015823.1|UniProtKB=W5NFR9 W5NFR9 PTHR32289:SF3 PROTEIN FAM167A PROTEIN FAM167A LEPOC|Ensembl=ENSLOCG00000001292.1|UniProtKB=W5LZA9 W5LZA9 PTHR23060:SF3 TESTIS EXPRESSED GENE 14 TESTIS EXPRESSED 14, INTERCELLULAR BRIDGE FORMING FACTOR LEPOC|Ensembl=ENSLOCG00000008603.1|UniProtKB=W5MPZ9 W5MPZ9 ZNF608 PTHR21564:SF4 BRAKELESS PROTEIN ZINC FINGER PROTEIN 608 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011402.1|UniProtKB=W5N068 W5N068 PTHR11451:SF54 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004607.1|UniProtKB=W5MAV8 W5MAV8 DEDD2 PTHR15205:SF1 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DNA-BINDING DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011187.1|UniProtKB=W5MZD5 W5MZD5 PTHR28556:SF1 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106B LEPOC|Ensembl=ENSLOCG00000002600.1|UniProtKB=W5M3V1 W5M3V1 PTHR13045:SF14 5'-NUCLEOTIDASE CYTOSOLIC 5'-NUCLEOTIDASE 3A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000006711.1|UniProtKB=W5MI95 W5MI95 PTHR24416:SF134 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;Wnt-protein binding#GO:0017147;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011284.1|UniProtKB=W5MZQ7 W5MZQ7 PTHR45941:SF1 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 carbohydrate biosynthetic process#GO:0016051;oligosaccharide biosynthetic process#GO:0009312;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000014982.1|UniProtKB=W5NCT5 W5NCT5 PTHR24243:SF227 G-PROTEIN COUPLED RECEPTOR MOTILIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016100.1|UniProtKB=W5NGT0 W5NGT0 PTHR11647:SF56 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125;Axon guidance mediated by semaphorins#P00007>CRMP#P00339 LEPOC|Ensembl=ENSLOCG00000016226.1|UniProtKB=W5NH97 W5NH97 SGK1 PTHR24351:SF184 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000284.1|UniProtKB=W5LW06 W5LW06 PTHR10352:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 1 translation initiation factor#PC00224;translation factor#PC00223 CCKR signaling map#P06959>HuR#G07273;CCKR signaling map#P06959>HuR#P07211;CCKR signaling map#P06959>HuR#G06980 LEPOC|Ensembl=ENSLOCG00000001166.1|UniProtKB=W5LYV9 W5LYV9 PTHR12326:SF3 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG LEPOC|Ensembl=ENSLOCG00000006838.1|UniProtKB=W5MIU0 W5MIU0 PTHR22754:SF38 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG B LEPOC|Ensembl=ENSLOCG00000009174.1|UniProtKB=W5MS31 W5MS31 PTHR21552:SF2 ADULT RETINA PROTEIN CREB3 REGULATORY FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013385.1|UniProtKB=W5N790 W5N790 PTHR11560:SF8 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014501.1|UniProtKB=W5NB37 W5NB37 PTHR45736:SF8 ZINC FINGER MYM-TYPE PROTEIN TRANSCRIPTIONAL REGULATOR QRICH1 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011588.1|UniProtKB=W5N0T1 W5N0T1 PTHR14928:SF6 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007661.1|UniProtKB=W5MLP5 W5MLP5 PTHR45888:SF2 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2D N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;histone H3K4 methyltransferase activity#GO:0042800;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000006226.1|UniProtKB=W5MGM5 W5MGM5 PTHR24056:SF107 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017923.1|UniProtKB=W5NN17 W5NN17 PTHR11589:SF10 NERVE GROWTH FACTOR NGF -RELATED BETA-NERVE GROWTH FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;response to growth factor#GO:0070848;regulation of signaling#GO:0023051;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;generation of neurons#GO:0048699 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;extracellular region#GO:0005576;cell junction#GO:0030054;dendrite#GO:0030425;extracellular space#GO:0005615;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000017559.1|UniProtKB=W5NM05 W5NM05 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007899.1|UniProtKB=W5MMI4 W5MMI4 PTHR10201:SF323 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000015198.1|UniProtKB=W5NDJ9 W5NDJ9 PTHR24075:SF5 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011332.1|UniProtKB=W5MZW4 W5MZW4 PTHR19143:SF433 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;complement activation#GO:0006956 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007827.1|UniProtKB=W5MM94 W5MM94 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT EPSILON antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 globin#PC00107 LEPOC|Ensembl=ENSLOCG00000013023.1|UniProtKB=W5N5Y4 W5N5Y4 PTHR23389:SF6 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 DNA metabolism protein#PC00009 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000009810.1|UniProtKB=W5MUC6 W5MUC6 RNF168 PTHR23328:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF168 nucleosome binding#GO:0031491;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018089.1|UniProtKB=W5NNI1 W5NNI1 PTHR24366:SF97 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS EXTRACELLULAR LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 1 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000011121.1|UniProtKB=W5MZ56 W5MZ56 PTHR47978:SF64 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-37 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;regulation of vesicle-mediated transport#GO:0060627;regulation of exocytosis#GO:0017157 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000810.1|UniProtKB=W5LXP5 W5LXP5 PTHR10751:SF1 GUANYLATE BINDING PROTEIN RING FINGER PROTEIN 112 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000008029.1|UniProtKB=W5MMZ6 W5MMZ6 SLC9A3 PTHR10110:SF90 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 3 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001497.1|UniProtKB=W5M001 W5M001 PTHR23266:SF403 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017890.1|UniProtKB=W5NMY4 W5NMY4 PTHR24229:SF6 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;response to estradiol#GO:0032355;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to steroid hormone#GO:0048545 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000003856.1|UniProtKB=W5M896 W5M896 PTHR12011:SF264 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000280.1|UniProtKB=W5LVZ9 W5LVZ9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013853.1|UniProtKB=W5N8X7 W5N8X7 PTHR24103:SF692 E3 UBIQUITIN-PROTEIN LIGASE TRIM B30.2_SPRY DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014375.1|UniProtKB=W5NAP2 W5NAP2 PTHR10953:SF162 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000007758.1|UniProtKB=W5MM16 W5MM16 PTHR48078:SF16 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED SERINE DEHYDRATASE-LIKE lyase activity#GO:0016829;catalytic activity#GO:0003824 branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000008272.1|UniProtKB=W5MNU0 W5MNU0 PTHR23101:SF103 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP_GTP EXCHANGE FACTOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012008.1|UniProtKB=W5N2B1 W5N2B1 PTHR21635:SF0 LEUCINE ZIPPER TRANSCRIPTION FACTOR LIKE LEUCINE ZIPPER TRANSCRIPTION FACTOR-LIKE PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular localization#GO:0060341;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000005789.1|UniProtKB=W5MF31 W5MF31 PTHR24254:SF10 PROTHROMBIN PROTHROMBIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;platelet activation#GO:0030168;regulation of coagulation#GO:0050818;regulation of response to stress#GO:0080134;regulation of body fluid levels#GO:0050878;wound healing#GO:0042060;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;regulation of response to wounding#GO:1903034;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of wound healing#GO:0061041;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 Blood coagulation#P00011>Prothrombin#P00416;Blood coagulation#P00011>Thrombin#P00414 LEPOC|Ensembl=ENSLOCG00000005713.1|UniProtKB=W5MEU0 W5MEU0 PTHR45808:SF6 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of localization#GO:0032879;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000010182.1|UniProtKB=W5MVQ7 W5MVQ7 PTHR14972:SF6 AGAP011572-PA PROTEIN FAM117B LEPOC|Ensembl=ENSLOCG00000009208.1|UniProtKB=W5MS70 W5MS70 PTHR12027:SF88 WNT RELATED PROTEIN WNT-3A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000014804.1|UniProtKB=W5NC71 W5NC71 PTHR10288:SF162 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006135.1|UniProtKB=W5MGA4 W5MGA4 PTHR23227:SF83 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013427.1|UniProtKB=W5N7E7 W5N7E7 PTHR15129:SF1 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 1 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013899.1|UniProtKB=W5N926 W5N926 PTHR46169:SF17 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004772.1|UniProtKB=W5MBG6 W5MBG6 PTHR43053:SF4 GLYCOSIDASE FAMILY 31 MYOGENESIS-REGULATING GLYCOSIDASE glucosidase#PC00108 LEPOC|Ensembl=ENSLOCG00000005887.1|UniProtKB=W5MFF2 W5MFF2 PTHR12374:SF20 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001951.1|UniProtKB=W5M1J7 W5M1J7 PTHR12935:SF14 GAMMA-GLUTAMYLCYCLOTRANSFERASE GAMMA-GLUTAMYLCYCLOTRANSFERASE lyase activity#GO:0016829;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000006084.1|UniProtKB=W5MG43 W5MG43 PTHR10285:SF131 URIDINE KINASE URIDINE-CYTIDINE KINASE 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 LEPOC|Ensembl=ENSLOCG00000020990.1|UniProtKB=Q8HQM6 Q8HQM6 ND3 PTHR11058:SF9 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215 oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964;catalytic complex#GO:1902494 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016251.1|UniProtKB=W5NHD1 W5NHD1 PTHR48439:SF1 HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015576.1|UniProtKB=W5NEW8 W5NEW8 PTHR47981:SF3 RAB FAMILY RAB7B, MEMBER RAS ONCOGENE FAMILY lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000006225.1|UniProtKB=W5MGL2 W5MGL2 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002882.1|UniProtKB=W5M4S9 W5M4S9 PTHR21580:SF21 SHIPPO-1-RELATED O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2 apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000018076.1|UniProtKB=W5NNG8 W5NNG8 PTHR11505:SF205 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014403.1|UniProtKB=W5NAU0 W5NAU0 PTHR11920:SF349 GUANYLYL CYCLASE RETINAL GUANYLYL CYCLASE 2 adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000014006.1|UniProtKB=W5N9G8 W5N9G8 PTHR24351:SF115 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 p38 MAPK pathway#P05918>MSK1#P06040;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000006957.1|UniProtKB=W5MJ52 W5MJ52 PTHR23041:SF78 RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF4 LEPOC|Ensembl=ENSLOCG00000002973.1|UniProtKB=W5M543 W5M543 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003942.1|UniProtKB=W5M8J8 W5M8J8 PTHR12241:SF154 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL11 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014863.1|UniProtKB=W5NCE4 W5NCE4 PTHR35441:SF2 CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;circadian regulation of gene expression#GO:0032922;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002786.1|UniProtKB=W5M4I3 W5M4I3 PTHR42985:SF11 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004530.1|UniProtKB=W5MAM0 W5MAM0 PTHR11255:SF38 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012201.1|UniProtKB=W5N303 W5N303 PTHR45881:SF3 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000006853.1|UniProtKB=W5MIV1 W5MIV1 PTHR23172:SF4 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED TYROSINE-PROTEIN PHOSPHATASE AUXILIN-RELATED protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;protein-containing complex disassembly#GO:0032984;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;vesicle#GO:0031982;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006862.1|UniProtKB=W5MIU1 W5MIU1 PTHR24012:SF812 RNA BINDING PROTEIN RNA-BINDING PROTEIN 45 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007544.1|UniProtKB=W5ML95 W5ML95 PTHR12191:SF21 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP4 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008095.1|UniProtKB=W5MN91 W5MN91 PTHR22881:SF4 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014820.1|UniProtKB=W5NC94 W5NC94 PTHR43272:SF93 LONG-CHAIN-FATTY-ACID--COA LIGASE ACYL-COA SYNTHETASE BUBBLEGUM FAMILY MEMBER 1 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012614.1|UniProtKB=W5N4H2 W5N4H2 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000992.1|UniProtKB=W5LYC6 W5LYC6 C1orf50 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO CHROMOSOME 1 OPEN READING FRAME 50 LEPOC|Ensembl=ENSLOCG00000013912.1|UniProtKB=W5N946 W5N946 SLC7A2 PTHR43243:SF35 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 2 L-lysine transmembrane transporter activity#GO:0015189;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017170.1|UniProtKB=W5NKR4 W5NKR4 PTHR10827:SF91 RETICULOCALBIN RETICULOCALBIN 3, EF-HAND CALCIUM BINDING DOMAIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008460.1|UniProtKB=W5MPI9 W5MPI9 PTHR14074:SF14 HELICASE WITH DEATH DOMAIN-RELATED INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;double-stranded RNA binding#GO:0003725 response to virus#GO:0009615;immune response-regulating signaling pathway#GO:0002764;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response to virus#GO:0051607;intracellular receptor signaling pathway#GO:0030522;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;immune response#GO:0006955;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;defense response to other organism#GO:0098542;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;immune response-activating signaling pathway#GO:0002757 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002683.1|UniProtKB=W5M466 W5M466 PTHR42861:SF6 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 3 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005117.1|UniProtKB=W5MCQ0 W5MCQ0 PTHR15240:SF1 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;plasma membrane raft#GO:0044853;caveola#GO:0005901;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016126.1|UniProtKB=W5NGW4 W5NGW4 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013138.1|UniProtKB=W5N6D2 W5N6D2 PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000017121.1|UniProtKB=W5NKJ9 W5NKJ9 PTHR30612:SF0 SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM CHLOROPLAST PROTEIN-TRANSPORTING ATPASE nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008049.1|UniProtKB=W5MN16 W5MN16 FNIP2 PTHR21634:SF11 RE13835P FOLLICULIN-INTERACTING PROTEIN 2 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011030.1|UniProtKB=W5MYU2 W5MYU2 PTHR39319:SF1 SI:DKEY-256H2.1 SI:DKEY-256H2.1 LEPOC|Ensembl=ENSLOCG00000002662.1|UniProtKB=W5M423 W5M423 PTHR44699:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010384.1|UniProtKB=W5MWG6 W5MWG6 PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;small GTPase-mediated signal transduction#GO:0007264;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;cellular response to nitrogen compound#GO:1901699;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of exocytosis#GO:0017157;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 LEPOC|Ensembl=ENSLOCG00000003792.1|UniProtKB=W5M839 W5M839 PTHR43150:SF1 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-2 binding#GO:0005488;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;channel regulator activity#GO:0016247;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of potassium ion transport#GO:0043266;regulation of monoatomic cation transmembrane transport#GO:1904062 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;main axon#GO:0044304;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015648.1|UniProtKB=W5NF52 W5NF52 PTHR23282:SF137 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006989.1|UniProtKB=W5MJ95 W5MJ95 PTHR19297:SF178 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009400.1|UniProtKB=W5MSW7 W5MSW7 PTHR10404:SF81 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006049.1|UniProtKB=W5MFZ5 W5MFZ5 PTHR24412:SF215 KELCH PROTEIN KELCH-LIKE PROTEIN 24 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006024.1|UniProtKB=W5MFW7 W5MFW7 PTHR45915:SF1 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012452.1|UniProtKB=W5N3X3 W5N3X3 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001391.1|UniProtKB=W5LZM7 W5LZM7 PTHR23101:SF126 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP_GTP EXCHANGE FACTOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009356.1|UniProtKB=W5MSQ4 W5MSQ4 PTHR23277:SF12 NECTIN-RELATED NECTIN-3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;apical junction complex#GO:0043296 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008495.1|UniProtKB=W5MPN7 W5MPN7 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012612.1|UniProtKB=W5N4G6 W5N4G6 PTHR14388:SF5 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004761.1|UniProtKB=W5MBF3 W5MBF3 PTHR24124:SF4 ANKYRIN REPEAT FAMILY A DNA-BINDING PROTEIN RFXANK positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010023.1|UniProtKB=W5MV44 W5MV44 PRAG1 PTHR22972:SF3 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PRAG1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012295.1|UniProtKB=W5N3B7 W5N3B7 PTHR22923:SF61 CEREBELLIN-RELATED C1Q AND TNF RELATED 8 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001346.1|UniProtKB=W5LZJ3 W5LZJ3 PTHR46240:SF1 SER/THR PROTEIN KINASE ULK4 SERINE_THREONINE-PROTEIN KINASE ULK4 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011200.1|UniProtKB=W5MZG2 W5MZG2 PTHR11532:SF92 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 CCKR signaling map#P06959>Carboxypeptidase E#P07026;Vasopressin synthesis#P04395>Exopeptidase#P04592 LEPOC|Ensembl=ENSLOCG00000008473.1|UniProtKB=W5MPK2 W5MPK2 PTHR34917:SF1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of cell communication#GO:0010646;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;transport#GO:0006810;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;nuclear transport#GO:0051169;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015687.1|UniProtKB=W5NFA1 W5NFA1 PTHR24365:SF522 TOLL-LIKE RECEPTOR LOW QUALITY PROTEIN: TOLL-LIKE RECEPTOR 13-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004934.1|UniProtKB=W5MC24 W5MC24 PTHR16201:SF53 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED TRANSMEMBRANE PROTEIN 44 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;basic amino acid transmembrane transporter activity#GO:0015174;organic acid transmembrane transporter activity#GO:0005342 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004215.1|UniProtKB=W5M9I5 W5M9I5 EIF3B PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002509.1|UniProtKB=W5M3K4 W5M3K4 PTHR46022:SF3 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008285.1|UniProtKB=W5MNV4 W5MNV4 PTHR14739:SF9 MICROTUBULE-ASSOCIATED PROTEIN 9 MICROTUBULE-ASSOCIATED PROTEIN 9 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;regulation of cytokinesis#GO:0032465;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;chromosome organization#GO:0051276;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000221.1|UniProtKB=W5LVT8 W5LVT8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006429.1|UniProtKB=W5MHC6 W5MHC6 PTHR16301:SF25 IMPACT-RELATED PROTEIN IMPACT cellular response to stimulus#GO:0051716;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;cellular process#GO:0009987;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004834.1|UniProtKB=W5MBP8 W5MBP8 PTHR13580:SF6 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 2 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006088.1|UniProtKB=W5MG51 W5MG51 PTHR21254:SF1 C2 DOMAIN-CONTAINING PROTEIN 3 C2 DOMAIN-CONTAINING PROTEIN 3 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006572.1|UniProtKB=W5MHS9 W5MHS9 PTHR24393:SF138 ZINC FINGER PROTEIN IP01201P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009391.1|UniProtKB=W5MSU5 W5MSU5 PTHR24030:SF0 PROTEIN CMSS1 PROTEIN CMSS1 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;90S preribosome#GO:0030686;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017191.1|UniProtKB=W5NKT7 W5NKT7 PTHR47059:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 32 TETRATRICOPEPTIDE REPEAT PROTEIN 32 LEPOC|Ensembl=ENSLOCG00000014487.1|UniProtKB=W5NB19 W5NB19 PTHR16768:SF4 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B ISOFORM X1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;synapse#GO:0045202;actin filament bundle#GO:0032432;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;cytoskeleton#GO:0005856;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000000552.1|UniProtKB=W5LWV2 W5LWV2 PTHR14454:SF6 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 LEPOC|Ensembl=ENSLOCG00000016313.1|UniProtKB=W5NHM6 W5NHM6 PTHR23050:SF523 CALCIUM BINDING PROTEIN CALMODULIN cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 LEPOC|Ensembl=ENSLOCG00000000764.1|UniProtKB=W5LXJ9 W5LXJ9 PTHR21274:SF1 MECKELIN TRANSMEMBRANE PROTEIN 67 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000015353.1|UniProtKB=W5NE35 W5NE35 PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cell death#GO:0008219;programmed cell death#GO:0012501;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 LEPOC|Ensembl=ENSLOCG00000006651.1|UniProtKB=W5MI22 W5MI22 PTHR10333:SF41 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of apoptotic signaling pathway#GO:2001233;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014334.1|UniProtKB=W5NAJ0 W5NAJ0 PTHR11848:SF22 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 15 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000008687.1|UniProtKB=W5MQA9 W5MQA9 PTHR16253:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 22 TETRATRICOPEPTIDE REPEAT PROTEIN 22 LEPOC|Ensembl=ENSLOCG00000016269.1|UniProtKB=W5NHG2 W5NHG2 PTHR11875:SF70 TESTIS-SPECIFIC Y-ENCODED PROTEIN HYPOTHETICAL GENE SUPPORTED BY NM_053561_ AF062594 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017960.1|UniProtKB=W5NN54 W5NN54 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008877.1|UniProtKB=W5MQZ9 W5MQZ9 PTHR13703:SF23 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 LEPOC|Ensembl=ENSLOCG00000007110.1|UniProtKB=W5MJQ0 W5MJQ0 PTHR10201:SF224 MATRIX METALLOPROTEINASE MATRIX METALLOPEPTIDASE 17B hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013438.1|UniProtKB=W5N7G6 W5N7G6 PTHR48041:SF92 ABC TRANSPORTER G FAMILY MEMBER 28 BROAD SUBSTRATE SPECIFICITY ATP-BINDING CASSETTE TRANSPORTER ABCG2 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;efflux transmembrane transporter activity#GO:0015562;ATPase-coupled transmembrane transporter activity#GO:0042626;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014818.1|UniProtKB=W5NC88 W5NC88 PTHR11239:SF1 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;RNA polymerase activity#GO:0097747;transferase activity, transferring phosphorus-containing groups#GO:0016772 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;transcription elongation by RNA polymerase II#GO:0006368;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000011314.1|UniProtKB=W5MZU8 W5MZU8 PTHR22809:SF4 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2A-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000003493.1|UniProtKB=W5M708 W5M708 PTHR22762:SF133 ALPHA-GLUCOSIDASE P-TYPE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017638.1|UniProtKB=W5NM84 W5NM84 C2CD4C PTHR46291:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C LEPOC|Ensembl=ENSLOCG00000012576.1|UniProtKB=W5N4C0 W5N4C0 PTHR13594:SF2 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA SI:CH73-100L22.3 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;centriole assembly#GO:0098534;cell projection organization#GO:0030030;negative regulation of cell cycle#GO:0045786;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;negative regulation of cell cycle process#GO:0010948;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;plasma membrane bounded cell projection organization#GO:0120036;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;non-membrane-bounded organelle assembly#GO:0140694;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008589.1|UniProtKB=W5MPY5 W5MPY5 GRAMD2B PTHR46645:SF2 GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED GRAM DOMAIN-CONTAINING PROTEIN 2B supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009290.1|UniProtKB=W5MSG9 W5MSG9 PTHR22437:SF1 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003237.1|UniProtKB=W5M612 W5M612 THAP1 PTHR46600:SF7 THAP DOMAIN-CONTAINING SI:DKEY-228B2.6-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000162.1|UniProtKB=W5LVM0 W5LVM0 PTHR48071:SF24 SRCR DOMAIN-CONTAINING PROTEIN DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-LIKE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005956.1|UniProtKB=W5MFN6 W5MFN6 DPY19L4 PTHR31488:SF2 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L4-RELATED mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010582.1|UniProtKB=W5MX58 W5MX58 PTHR44981:SF1 PERICENTRIN-LIKE PROTEIN, ISOFORM F A-KINASE ANCHOR PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000004955.1|UniProtKB=W5MC47 W5MC47 PTHR45775:SF3 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN RAD carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;transporter regulator activity#GO:0141108;anion binding#GO:0043168;channel regulator activity#GO:0016247;ion binding#GO:0043167 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004245.1|UniProtKB=W5M9L6 W5M9L6 PTHR11247:SF1 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 DOLICHYLDIPHOSPHATASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012915.1|UniProtKB=W5N5K1 W5N5K1 PDE1C PTHR11347:SF32 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;cellular anatomical entity#GO:0110165;cell body#GO:0044297;neuronal cell body#GO:0043025 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000006631.1|UniProtKB=W5MI03 W5MI03 PTHR14167:SF63 SH3 DOMAIN-CONTAINING ENDOPHILIN-A2 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;protein-containing complex disassembly#GO:0032984;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005344.1|UniProtKB=W5MDI0 W5MDI0 LRRC43 PTHR45973:SF35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 43 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000015541.1|UniProtKB=W5NES1 W5NES1 PTHR48039:SF5 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 LEPOC|Ensembl=ENSLOCG00000004404.1|UniProtKB=W5MA52 W5MA52 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000003240.1|UniProtKB=W5M619 W5M619 PTHR14239:SF8 DUDULIN-RELATED METALLOREDUCTASE STEAP3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003657.1|UniProtKB=W5M7K0 W5M7K0 PTHR43939:SF122 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000015502.1|UniProtKB=W5NEM1 W5NEM1 PTHR43804:SF3 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1-LIKE, MITOCHONDRIAL protein-containing complex disassembly#GO:0032984;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;translational termination#GO:0006415;peptide biosynthetic process#GO:0043043;cellular component disassembly#GO:0022411;protein-containing complex organization#GO:0043933;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001439.1|UniProtKB=W5LZV0 W5LZV0 PTHR10454:SF13 CASPASE CASPASE-4 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of response to external stimulus#GO:0032101;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;positive regulation of response to external stimulus#GO:0032103;regulation of response to stress#GO:0080134;programmed cell death#GO:0012501;positive regulation of inflammatory response#GO:0050729;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of defense response#GO:0031349;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003937.1|UniProtKB=W5M8K0 W5M8K0 PTHR45633:SF3 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000018314.1|UniProtKB=W5NP56 W5NP56 PTHR24241:SF178 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017740.1|UniProtKB=W5NMI5 W5NMI5 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016004.1|UniProtKB=W5NGF0 W5NGF0 RSBN1L PTHR13354:SF9 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE RSBN1L membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004047.1|UniProtKB=W5M8X1 W5M8X1 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000001238.1|UniProtKB=W5LZ50 W5LZ50 PTHR12353:SF19 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 4 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of system process#GO:0044057 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012208.1|UniProtKB=W5N310 W5N310 PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001397.1|UniProtKB=W5LZM9 W5LZM9 PTHR24351:SF243 RIBOSOMAL PROTEIN S6 KINASE SERUM_GLUCOCORTICOID REGULATED KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013137.1|UniProtKB=W5N6C6 W5N6C6 SYCP2L PTHR15607:SF18 SYNAPTONEMAL COMPLEX PROTEIN-RELATED SYNAPTONEMAL COMPLEX PROTEIN 2-LIKE ISOFORM X1 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013099.1|UniProtKB=W5N680 W5N680 PTHR24123:SF49 ANKYRIN REPEAT-CONTAINING ANKYRIN-2-LIKE ISOFORM X1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001489.1|UniProtKB=W5LZZ1 W5LZZ1 PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000224.1|UniProtKB=W5LVU2 W5LVU2 KCNK4 PTHR11003:SF30 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015817.1|UniProtKB=W5NFR5 W5NFR5 COG5 PTHR13228:SF3 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001566.1|UniProtKB=W5M082 W5M082 MED26 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of gene expression#GO:0010628;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011118.1|UniProtKB=W5MZ50 W5MZ50 PTHR11576:SF15 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3-LIKE enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000015960.1|UniProtKB=W5NG93 W5NG93 PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015932.1|UniProtKB=W5NG61 W5NG61 VIT PTHR24020:SF23 COLLAGEN ALPHA VITRIN regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;positive regulation of cell-substrate adhesion#GO:0010811;external encapsulating structure organization#GO:0045229;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular component organization#GO:0016043;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;extracellular matrix organization#GO:0030198;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cellular process#GO:0048522 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003433.1|UniProtKB=W5M6U0 W5M6U0 PTHR19384:SF63 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor#GO:0016653;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;system process#GO:0003008;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;alpha-amino acid metabolic process#GO:1901605;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;response to molecule of bacterial origin#GO:0002237;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;regulation of lyase activity#GO:0051339;response to oxygen-containing compound#GO:1901700;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;circulatory system process#GO:0003013;organic acid metabolic process#GO:0006082;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;blood circulation#GO:0008015;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;response to lipid#GO:0033993;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;amino acid catabolic process#GO:0009063;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;L-amino acid metabolic process#GO:0170033;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;proteinogenic amino acid metabolic process#GO:0170039;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;arginine metabolic process#GO:0006525;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of blood pressure#GO:0008217;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of lyase activity#GO:0051349;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;plasma membrane#GO:0005886 oxidoreductase#PC00176 CCKR signaling map#P06959>NOS1#P07158;Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#P06741;Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#G06888 LEPOC|Ensembl=ENSLOCG00000010250.1|UniProtKB=W5MVY3 W5MVY3 PTHR15076:SF15 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;positive regulation of immune system process#GO:0002684;homotypic cell-cell adhesion#GO:0034109;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of leukocyte migration#GO:0002687;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;immune system process#GO:0002376;mononuclear cell migration#GO:0071674;leukocyte migration#GO:0050900;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;lymphocyte migration#GO:0072676;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;cell migration#GO:0016477;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013061.1|UniProtKB=W5N637 W5N637 PTHR13817:SF106 TITIN PALLADIN, CYTOSKELETAL ASSOCIATED PROTEIN structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010793.1|UniProtKB=W5MXW6 W5MXW6 STK32A PTHR24356:SF143 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006988.1|UniProtKB=W5MJ94 W5MJ94 PTHR46693:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000001253.1|UniProtKB=W5LZ80 W5LZ80 PTHR43795:SF17 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 1 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014335.1|UniProtKB=W5NAM9 W5NAM9 COL4A6 PTHR24023:SF533 COLLAGEN ALPHA COLLAGEN ALPHA-6(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000002057.1|UniProtKB=W5M1Y3 W5M1Y3 PTHR11088:SF89 TRNA DIMETHYLALLYLTRANSFERASE TRNA DIMETHYLALLYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010923.1|UniProtKB=W5MYH1 W5MYH1 PTHR22625:SF37 PLEXIN PLEXIN-A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001561.1|UniProtKB=W5M078 W5M078 PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD LEPOC|Ensembl=ENSLOCG00000017337.1|UniProtKB=W5NLD3 W5NLD3 PTHR15895:SF14 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000004324.1|UniProtKB=W5M9W0 W5M9W0 PTHR16213:SF78 SELENOPROTEIN N SELENOPROTEIN N skeletal muscle organ development#GO:0060538;inorganic ion homeostasis#GO:0098771;cellular developmental process#GO:0048869;muscle organ development#GO:0007517;muscle cell differentiation#GO:0042692;calcium ion homeostasis#GO:0055074;animal organ development#GO:0048513;developmental process#GO:0032502;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;monoatomic ion homeostasis#GO:0050801;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;anatomical structure development#GO:0048856;skeletal muscle tissue development#GO:0007519 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003955.1|UniProtKB=W5M8M3 W5M8M3 PTHR12112:SF9 BNIP - RELATED CAYTAXIN cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009744.1|UniProtKB=W5MU45 W5MU45 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 LEPOC|Ensembl=ENSLOCG00000018201.1|UniProtKB=W5NNU3 W5NNU3 PTHR14315:SF20 SPOT14 FAMILY MEMBER SIMILAR TO VERTEBRATE MID1 INTERACTING-LIKE PROTEIN biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015640.1|UniProtKB=W5NF46 W5NF46 FAHD2B PTHR42796:SF4 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006279.1|UniProtKB=W5MGS7 W5MGS7 PTHR42884:SF28 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 7 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000005400.1|UniProtKB=W5MDS1 W5MDS1 PTHR11388:SF14 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013862.1|UniProtKB=W5N8Y6 W5N8Y6 PTHR14826:SF6 ANGIOMOTIN ANGIOMOTIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cytoskeleton organization#GO:0007010;vasculature development#GO:0001944;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;tube development#GO:0035295;ameboidal-type cell migration#GO:0001667;cell communication#GO:0007154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;hippo signaling#GO:0035329;response to stimulus#GO:0050896;angiogenesis#GO:0001525;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell leading edge#GO:0031252;tight junction#GO:0070160;lamellipodium#GO:0030027;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;apical junction complex#GO:0043296;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000002072.1|UniProtKB=W5M218 W5M218 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000008866.1|UniProtKB=W5MQY5 W5MQY5 PTHR23408:SF3 METHYLMALONYL-COA MUTASE METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000008303.1|UniProtKB=W5MNX7 W5MNX7 PTHR12289:SF34 METAXIN RELATED METAXIN-1 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017792.1|UniProtKB=W5NMN7 W5NMN7 CLDN34 PTHR12002:SF4 CLAUDIN CLAUDIN-34 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000016315.1|UniProtKB=W5NHM8 W5NHM8 PTHR35678:SF1 PROTEIN STPG4 PROTEIN STPG4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000286.1|UniProtKB=W5LW05 W5LW05 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000014032.1|UniProtKB=W5N9K6 W5N9K6 ADAMTS7 PTHR13723:SF142 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 7 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017802.1|UniProtKB=W5NMP7 W5NMP7 PTHR13563:SF5 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG C tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;tRNA metabolic process#GO:0006399;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;positive regulation of cellular metabolic process#GO:0031325;mitochondrial gene expression#GO:0140053;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;mitochondrial RNA processing#GO:0000963;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;RNA methylation#GO:0001510;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000002635.1|UniProtKB=W5M3Y7 W5M3Y7 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001562.1|UniProtKB=W5M080 W5M080 PTHR21621:SF0 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN BETA-CITRYLGLUTAMATE SYNTHASE B-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000861.1|UniProtKB=W5LXV1 W5LXV1 PTHR23266:SF398 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-30 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016692.1|UniProtKB=W5NJ12 W5NJ12 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN MS35 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002193.1|UniProtKB=W5M2G7 W5M2G7 PTHR13886:SF3 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;signaling receptor complex adaptor activity#GO:0030159;kinase binding#GO:0019900 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010440.1|UniProtKB=W5MWN4 W5MWN4 PTHR24070:SF189 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE NRAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;FGF signaling pathway#P00021>Ras#P00633;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Angiogenesis#P00005>Ras#P00238;T cell activation#P00053>Ras#P01306;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;B cell activation#P00010>Ras#P00376;Interleukin signaling pathway#P00036>Ras#P00977;Ras Pathway#P04393>Ras#P04547;PI3 kinase pathway#P00048>Ras#P01182;p53 pathway feedback loops 2#P04398>Ras#P04651;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916 LEPOC|Ensembl=ENSLOCG00000000429.1|UniProtKB=W5LWH5 W5LWH5 PTHR12011:SF290 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G6 signaling receptor activity#GO:0038023;extracellular matrix binding#GO:0050840;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 heart development#GO:0007507;signal transduction#GO:0007165;neurogenesis#GO:0022008;animal organ development#GO:0048513;developmental process#GO:0032502;gliogenesis#GO:0042063;peripheral nervous system development#GO:0007422;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;signaling#GO:0023052;cellular developmental process#GO:0048869;heart morphogenesis#GO:0003007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;myelination#GO:0042552 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000829.1|UniProtKB=W5LXR9 W5LXR9 PTHR15362:SF7 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 2 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011433.1|UniProtKB=W5N092 W5N092 PTHR12411:SF57 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L2 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009894.1|UniProtKB=W5MUQ2 W5MUQ2 PTHR10814:SF31 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 4 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 LEPOC|Ensembl=ENSLOCG00000017941.1|UniProtKB=W5NN35 W5NN35 LRRN2 PTHR24366:SF92 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 2 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000003634.1|UniProtKB=W5M7F4 W5M7F4 PTHR12675:SF4 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014751.1|UniProtKB=W5NC02 W5NC02 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 LEPOC|Ensembl=ENSLOCG00000020998.1|UniProtKB=Q8HQM2 Q8HQM2 ND6 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001773.1|UniProtKB=W5M0Z1 W5M0Z1 PTHR23423:SF80 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001307.1|UniProtKB=W5LZC9 W5LZC9 PTHR22883:SF49 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC7 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000341.1|UniProtKB=W5LW62 W5LW62 PTHR24369:SF102 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of synapse organization#GO:0050807;synaptic membrane adhesion#GO:0099560;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of synapse assembly#GO:0051965;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of postsynapse organization#GO:0099175;regulation of multicellular organismal process#GO:0051239;regulation of organelle organization#GO:0033043;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;positive regulation of multicellular organismal process#GO:0051240 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017654.1|UniProtKB=W5NMA0 W5NMA0 PTHR26451:SF896 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003203.1|UniProtKB=W5M5Y1 W5M5Y1 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000006725.1|UniProtKB=W5MIB1 W5MIB1 PTHR23167:SF37 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015383.1|UniProtKB=W5NE72 W5NE72 PTHR10185:SF9 PHOSPHOLIPASE D - RELATED INACTIVE PHOSPHOLIPASE D5 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000006849.1|UniProtKB=W5MIS0 W5MIS0 PTHR47142:SF1 BETA-CATENIN-INTERACTING PROTEIN 1 BETA-CATENIN-INTERACTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000263.1|UniProtKB=W5LVY6 W5LVY6 PTHR10796:SF60 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006387.1|UniProtKB=W5MH53 W5MH53 PTHR46165:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012908.1|UniProtKB=W5N5I6 W5N5I6 PTHR48078:SF19 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED ACT DOMAIN-CONTAINING PROTEIN lyase activity#GO:0016829;catalytic activity#GO:0003824 branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 dehydratase#PC00091;lyase#PC00144 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 LEPOC|Ensembl=ENSLOCG00000008557.1|UniProtKB=W5MPU8 W5MPU8 PTHR46643:SF2 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000835.1|UniProtKB=W5LXS3 W5LXS3 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000007005.1|UniProtKB=W5MJC2 W5MJC2 PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017;cilium movement#GO:0003341 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016043.1|UniProtKB=W5NGK2 W5NGK2 PTHR24034:SF110 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN DISULFIDE ISOMERASE CRELD2 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000016872.1|UniProtKB=W5NJP7 W5NJP7 PTHR24340:SF24 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016069.1|UniProtKB=W5NGP0 W5NGP0 PTHR11848:SF159 TGF-BETA FAMILY NODAL HOMOLOG molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000010789.1|UniProtKB=W5MXX0 W5MXX0 PTHR46530:SF1 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000012687.1|UniProtKB=W5N4Q2 W5N4Q2 PTHR24343:SF350 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011982.1|UniProtKB=W5N284 W5N284 PTHR13429:SF11 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 6 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;apical part of cell#GO:0045177 LEPOC|Ensembl=ENSLOCG00000006426.1|UniProtKB=W5MHA4 W5MHA4 PTHR14499:SF3 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD14 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010580.1|UniProtKB=W5MX50 W5MX50 PTHR15600:SF42 SACSIN SACSIN heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 LEPOC|Ensembl=ENSLOCG00000010976.1|UniProtKB=W5MYK2 W5MYK2 PTHR31345:SF3 CENTROMERE PROTEIN Q CENTROMERE PROTEIN Q LEPOC|Ensembl=ENSLOCG00000008881.1|UniProtKB=W5MR01 W5MR01 PTHR47979:SF8 DRAB11-RELATED RAS-RELATED PROTEIN RAB-25 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000009747.1|UniProtKB=W5MU72 W5MU72 PTHR11485:SF31 TRANSFERRIN SEROTRANSFERRIN response to external biotic stimulus#GO:0043207;metal ion transport#GO:0030001;immune response#GO:0006955;humoral immune response#GO:0006959;transport#GO:0006810;defense response to symbiont#GO:0140546;localization#GO:0051179;defense response to bacterium#GO:0042742;antibacterial humoral response#GO:0019731;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;establishment of localization#GO:0051234;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;defense response#GO:0006952;monoatomic ion transport#GO:0006811 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013861.1|UniProtKB=W5N8Y5 W5N8Y5 CARD14 PTHR14559:SF1 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 14 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017054.1|UniProtKB=W5NKB6 W5NKB6 PTHR34399:SF3 AVIDIN-RELATED AVID PROTEIN-RELATED small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 LEPOC|Ensembl=ENSLOCG00000010595.1|UniProtKB=W5MX66 W5MX66 PTHR11785:SF323 AMINO ACID TRANSPORTER CYSTINE_GLUTAMATE TRANSPORTER L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005963.1|UniProtKB=W5MFP1 W5MFP1 INHBC PTHR11848:SF6 TGF-BETA FAMILY INHIBIN BETA E CHAIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000003906.1|UniProtKB=W5M8F3 W5M8F3 PTHR45615:SF69 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-6 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000005864.1|UniProtKB=W5MFB9 W5MFB9 PTHR16833:SF0 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 DDIT3 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of biosynthetic process#GO:0009889;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;cellular response to biotic stimulus#GO:0071216;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>CHOP#P01130 LEPOC|Ensembl=ENSLOCG00000000554.1|UniProtKB=W5LWV4 W5LWV4 PTHR23277:SF109 NECTIN-RELATED POLIOVIRUS RECEPTOR cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016358.1|UniProtKB=W5NHT9 W5NHT9 PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 LEPOC|Ensembl=ENSLOCG00000001248.1|UniProtKB=W5LZ59 W5LZ59 PTHR14789:SF2 CHONDROLECTIN VARIANT CHODLFDELTAE. LAYILIN carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000001964.1|UniProtKB=W5M1L4 W5M1L4 PTHR24233:SF10 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013889.1|UniProtKB=W5N919 W5N919 PTHR24412:SF74 KELCH PROTEIN KELCH-LIKE PROTEIN 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015834.1|UniProtKB=W5NFT4 W5NFT4 PTHR45884:SF3 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000001053.1|UniProtKB=W5LYM7 W5LYM7 SAPCD2 PTHR14907:SF2 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000014224.1|UniProtKB=W5NA65 W5NA65 PTHR24543:SF317 MULTICOPPER OXIDASE-RELATED LACTADHERIN oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001016.1|UniProtKB=W5LYD5 W5LYD5 PTHR12081:SF43 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010804.1|UniProtKB=W5MXX7 W5MXX7 FAM237A PTHR36690:SF2 PROTEIN FAM237A PROTEIN FAM237A LEPOC|Ensembl=ENSLOCG00000012475.1|UniProtKB=W5N3Z9 W5N3Z9 PTPN7 PTHR46198:SF3 PROTEIN-TYROSINE-PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cell junction#GO:0030054;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001493.1|UniProtKB=W5M009 W5M009 PTHR11485:SF21 TRANSFERRIN MELANOTRANSFERRIN localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001474.1|UniProtKB=W5M007 W5M007 PTHR10857:SF4 COPINE COPINE-4 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000006833.1|UniProtKB=W5MIQ7 W5MIQ7 PTHR13069:SF21 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 LEPOC|Ensembl=ENSLOCG00000013215.1|UniProtKB=W5N6L9 W5N6L9 PTHR21472:SF19 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ZGC:172339 LEPOC|Ensembl=ENSLOCG00000003918.1|UniProtKB=W5M8N0 W5M8N0 PTHR11347:SF196 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;heterocycle catabolic process#GO:0046700;cyclic nucleotide metabolic process#GO:0009187;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;nucleotide catabolic process#GO:0009166;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;response to stimulus#GO:0050896;aromatic compound catabolic process#GO:0019439;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000007525.1|UniProtKB=W5ML69 W5ML69 PTHR12876:SF26 N4BP1-RELATED NEDD4-BINDING PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 regulation of proteolysis#GO:0030162;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;negative regulation of metabolic process#GO:0009892;regulation of protein catabolic process#GO:0042176;negative regulation of protein metabolic process#GO:0051248;regulation of proteolysis involved in protein catabolic process#GO:1903050;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein modification process#GO:0031400;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein ubiquitination#GO:0031397;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of proteolysis involved in protein catabolic process#GO:1903051;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;PML body#GO:0016605 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008627.1|UniProtKB=W5MQ44 W5MQ44 PTHR12187:SF4 AGAP000124-PA INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004113.1|UniProtKB=W5M958 W5M958 TMEM50B PTHR13180:SF2 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50B endosomal transport#GO:0016197;establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;late endosome to vacuole transport#GO:0045324;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 LEPOC|Ensembl=ENSLOCG00000000875.1|UniProtKB=W5LXX0 W5LXX0 PTHR23236:SF11 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000001582.1|UniProtKB=W5M0A6 W5M0A6 PTHR16650:SF9 C21ORF13-RELATED LEBERCILIN-LIKE PROTEIN cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000009982.1|UniProtKB=W5MUZ7 W5MUZ7 TLR8 PTHR47410:SF1 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;activation of immune response#GO:0002253;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;regulation of immune response#GO:0050776;canonical NF-kappaB signal transduction#GO:0007249;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;positive regulation of macromolecule metabolic process#GO:0010604;defense response to symbiont#GO:0140546;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;signal transduction#GO:0007165;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cytokine production#GO:0001817;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;regulation of cellular biosynthetic process#GO:0031326;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000015605.1|UniProtKB=W5NF07 W5NF07 PTHR46726:SF1 TWO PORE CHANNEL 3 TWO-PORE CALCIUM CHANNEL 3 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008383.1|UniProtKB=W5MPB2 W5MPB2 PTHR24040:SF7 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 3 LEPOC|Ensembl=ENSLOCG00000017652.1|UniProtKB=W5NM98 W5NM98 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008118.1|UniProtKB=W5MNA2 W5MNA2 PTHR23238:SF3 RNA BINDING PROTEIN RNA-BINDING PROTEIN EWS molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016938.1|UniProtKB=W5NJX8 W5NJX8 PM20D2 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;dicarboxylic acid metabolic process#GO:0043648;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular nitrogen compound catabolic process#GO:0044270;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008417.1|UniProtKB=W5MPC3 W5MPC3 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008031.1|UniProtKB=W5MMZ7 W5MMZ7 PTHR10556:SF59 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000836.1|UniProtKB=W5LXS5 W5LXS5 PTHR23351:SF13 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000013595.1|UniProtKB=W5N805 W5N805 PTHR28624:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 51 MITOCHONDRIAL POTASSIUM CHANNEL LEPOC|Ensembl=ENSLOCG00000017219.1|UniProtKB=W5NKY1 W5NKY1 CEP43 PTHR15431:SF9 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 43 LEPOC|Ensembl=ENSLOCG00000002694.1|UniProtKB=W5M456 W5M456 PTHR32493:SF0 SUSHI DOMAIN-CONTAINING PROTEIN 5 SUSHI DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;Notch signaling pathway#GO:0007219 LEPOC|Ensembl=ENSLOCG00000015352.1|UniProtKB=W5NE33 W5NE33 PTHR19877:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000012376.1|UniProtKB=W5N3P7 W5N3P7 PTHR45761:SF2 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-2 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007890.1|UniProtKB=W5MMH3 W5MMH3 PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;mismatch repair#GO:0006298;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007909.1|UniProtKB=W5MMJ8 W5MMJ8 PTHR19961:SF27 FIMBRIN/PLASTIN PLASTIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000009501.1|UniProtKB=W5MTA3 W5MTA3 PTHR46896:SF2 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 7 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000801.1|UniProtKB=W5LXN5 W5LXN5 PTHR39267:SF1 SURVIVAL MOTOR NEURON-LIKE PROTEIN 1 SURVIVAL MOTOR NEURON PROTEIN LEPOC|Ensembl=ENSLOCG00000009252.1|UniProtKB=W5MSC7 W5MSC7 PTHR15454:SF69 NISCHARIN RELATED SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013611.1|UniProtKB=W5N841 W5N841 PTHR11771:SF161 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15B oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000018112.1|UniProtKB=W5NNK4 W5NNK4 PTHR17045:SF7 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000015948.1|UniProtKB=W5NG78 W5NG78 PTHR10202:SF24 PRESENILIN PRESENILIN-2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein processing#GO:0016485;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling#GO:0023052;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;membrane protein proteolysis#GO:0033619;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cell communication#GO:0007154;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;membrane protein ectodomain proteolysis#GO:0006509;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;Notch signaling pathway#GO:0007219 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 aspartic protease#PC00053;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Pen-2#P01113;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098 LEPOC|Ensembl=ENSLOCG00000004943.1|UniProtKB=W5MC37 W5MC37 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2_IDD cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006142.1|UniProtKB=W5MGB5 W5MGB5 NUBP1 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002392.1|UniProtKB=W5M362 W5M362 ATP9A PTHR24092:SF49 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIA-RELATED ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;import into cell#GO:0098657;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017839.1|UniProtKB=W5NMT3 W5NMT3 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017408.1|UniProtKB=W5NLK4 W5NLK4 ZBTB38 PTHR24409:SF331 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 322A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017797.1|UniProtKB=W5NMP2 W5NMP2 PTHR12277:SF81 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013360.1|UniProtKB=W5N758 W5N758 PTHR12400:SF73 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000631.1|UniProtKB=W5LX44 W5LX44 CLSPN PTHR14396:SF10 CLASPIN CLASPIN LEPOC|Ensembl=ENSLOCG00000006968.1|UniProtKB=W5MJ72 W5MJ72 PTHR46967:SF1 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL KERATIN-ASSOCIATED PROTEIN 16-1-LIKE LEPOC|Ensembl=ENSLOCG00000010572.1|UniProtKB=W5MX42 W5MX42 MGARP PTHR22910:SF6 PROTEIN MGARP PROTEIN MGARP LEPOC|Ensembl=ENSLOCG00000017101.1|UniProtKB=W5NKI0 W5NKI0 PTHR45705:SF8 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of receptor-mediated endocytosis#GO:0048259 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004227.1|UniProtKB=W5M9K0 W5M9K0 PTHR11822:SF21 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008282.1|UniProtKB=W5MNX6 W5MNX6 PTHR43568:SF1 P PROTEIN P PROTEIN primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004454.1|UniProtKB=W5MAB4 W5MAB4 PTHR14009:SF13 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN 1 intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010490.1|UniProtKB=W5MWU8 W5MWU8 PTHR45752:SF156 LEUCINE-RICH REPEAT-CONTAINING RAS SUPPRESSOR PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006249.1|UniProtKB=W5MGN6 W5MGN6 PTHR11849:SF16 ETS TRANSCRIPTION FACTOR PU.1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>Ets#P00989 LEPOC|Ensembl=ENSLOCG00000011055.1|UniProtKB=W5MYW2 W5MYW2 NME2 PTHR11349:SF57 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 LEPOC|Ensembl=ENSLOCG00000017026.1|UniProtKB=W5NK85 W5NK85 PTHR19957:SF90 SYNTAXIN SYNTAXIN-7 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 LEPOC|Ensembl=ENSLOCG00000011410.1|UniProtKB=W5N071 W5N071 PTHR44054:SF1 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000001683.1|UniProtKB=W5M0N0 W5M0N0 PTHR45699:SF3 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001409.1|UniProtKB=W5LZQ6 W5LZQ6 PTHR46259:SF1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000004424.1|UniProtKB=W5MA76 W5MA76 PTHR19282:SF456 TETRASPANIN CD63 MOLECULE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002703.1|UniProtKB=W5M481 W5M481 PTHR44307:SF2 PHOSPHOETHANOLAMINE METHYLTRANSFERASE PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000014691.1|UniProtKB=W5NBS7 W5NBS7 PTHR45776:SF3 MIP04163P TRANSCRIPTION FACTOR E3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003913.1|UniProtKB=W5M8G7 W5M8G7 PTHR11923:SF112 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2 cargo receptor activity#GO:0038024 cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of catalytic activity#GO:0050790;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;endocytosis#GO:0006897;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015944.1|UniProtKB=W5NG71 W5NG71 PTHR11705:SF71 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A2 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008151.1|UniProtKB=W5MND5 W5MND5 PTHR11627:SF2 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE B lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aldolase#PC00044;lyase#PC00144 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 LEPOC|Ensembl=ENSLOCG00000017414.1|UniProtKB=W5NLL0 W5NLL0 PTHR47981:SF9 RAB FAMILY RAS-RELATED PROTEIN RAB-9A lysosome organization#GO:0007040;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014806.1|UniProtKB=W5NC70 W5NC70 PTHR23235:SF21 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 13 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017146.1|UniProtKB=W5NKN0 W5NKN0 PTHR16528:SF2 GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular localization#GO:0060341;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001478.1|UniProtKB=W5M000 W5M000 PTHR12411:SF554 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN 12 cysteine-type peptidase activity#GO:0008234;peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;positive regulation of apoptotic signaling pathway#GO:2001235;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004767.1|UniProtKB=W5MBG0 W5MBG0 PTHR28672:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein K11-linked ubiquitination#GO:0070979;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear ubiquitin ligase complex#GO:0000152;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000011548.1|UniProtKB=W5N0N0 W5N0N0 PTHR24214:SF5 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013158.1|UniProtKB=W5N6F2 W5N6F2 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000010833.1|UniProtKB=W5MY17 W5MY17 PTHR12490:SF4 GSK3B-INTERACTING PROTEIN GSK3B-INTERACTING PROTEIN protein kinase A binding#GO:0051018;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;binding#GO:0005488;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004862.1|UniProtKB=W5MBS8 W5MBS8 PTHR20843:SF1 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 10 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007200.1|UniProtKB=W5MK11 W5MK11 PTHR13742:SF8 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;developmental process#GO:0032502;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle process#GO:0010948;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015081.1|UniProtKB=W5ND53 W5ND53 PTHR11783:SF274 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013498.1|UniProtKB=W5N7M9 W5N7M9 PTHR43899:SF10 RH59310P 20BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016521.1|UniProtKB=W5NIE7 W5NIE7 PTHR22739:SF22 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED COSTARS DOMAIN-CONTAINING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011085.1|UniProtKB=W5MZ04 W5MZ04 PTHR23065:SF8 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synaptic vesicle recycling#GO:0036465;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000975.1|UniProtKB=W5LY89 W5LY89 SPATA16 PTHR47228:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002368.1|UniProtKB=W5M326 W5M326 PTHR13257:SF0 NUCLEOPORIN NUP84-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP88 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;ribosome biogenesis#GO:0042254;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008590.1|UniProtKB=W5MPY7 W5MPY7 PTHR10739:SF19 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A cation binding#GO:0043169;transferase activity#GO:0016740;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008215.1|UniProtKB=W5MNL5 W5MNL5 PTHR13054:SF2 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 LEPOC|Ensembl=ENSLOCG00000000757.1|UniProtKB=W5LXI4 W5LXI4 PTHR13109:SF7 NEUROCHONDRIN NEUROCHONDRIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007687.1|UniProtKB=W5MLS9 W5MLS9 PTHR11848:SF44 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 5 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000015971.1|UniProtKB=W5NGB0 W5NGB0 PTHR13693:SF56 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 3 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003580.1|UniProtKB=W5M794 W5M794 PTHR16294:SF7 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 2 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 LEPOC|Ensembl=ENSLOCG00000014423.1|UniProtKB=W5NAU3 W5NAU3 PTHR45690:SF19 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014570.1|UniProtKB=W5NBB9 W5NBB9 PTHR13345:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 PROTEIN UXT molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000010933.1|UniProtKB=W5MYE9 W5MYE9 PTHR19890:SF10 FIBROBLAST GROWTH FACTOR RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR-LIKE 1 transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 LEPOC|Ensembl=ENSLOCG00000011413.1|UniProtKB=W5N070 W5N070 PTHR14186:SF19 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000000923.1|UniProtKB=W5LY21 W5LY21 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006495.1|UniProtKB=W5MHJ2 W5MHJ2 PTHR19972:SF4 CALBINDIN CALRETININ cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;regulation of cell communication#GO:0010646;calcium ion homeostasis#GO:0055074;regulation of signaling#GO:0023051;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;regulation of synaptic plasticity#GO:0048167;monoatomic ion homeostasis#GO:0050801;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;intracellular monoatomic ion homeostasis#GO:0006873 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cytosol#GO:0005829;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010143.1|UniProtKB=W5MVK4 W5MVK4 PTHR13276:SF0 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 cation binding#GO:0043169;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;molecular function regulator activity#GO:0098772;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017962.1|UniProtKB=W5NN56 W5NN56 PTHR48043:SF63 EG:EG0003.4 PROTEIN-RELATED UDP GLUCURONOSYLTRANSFERASE 5 FAMILY, POLYPEPTIDE F1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 LEPOC|Ensembl=ENSLOCG00000002757.1|UniProtKB=W5M4D6 W5M4D6 UPK1B PTHR19282:SF514 TETRASPANIN UROPLAKIN 1B cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010089.1|UniProtKB=W5MVD2 W5MVD2 PTHR10901:SF5 TROPOMODULIN LEIOMODIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002082.1|UniProtKB=W5M252 W5M252 CLASP1 PTHR21567:SF28 CLASP CLIP-ASSOCIATING PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;cell cortex#GO:0005938;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;basal part of cell#GO:0045178;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000017649.1|UniProtKB=W5NM95 W5NM95 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006733.1|UniProtKB=W5MIC3 W5MIC3 PTHR12612:SF44 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012725.1|UniProtKB=W5N4U9 W5N4U9 CTSE PTHR47966:SF26 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN E hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 immune system process#GO:0002376;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;antigen processing and presentation#GO:0019882;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012867.1|UniProtKB=W5N5D7 W5N5D7 PTHR24115:SF434 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF19 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011839.1|UniProtKB=W5N1Q0 W5N1Q0 PTHR12589:SF7 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE LEPOC|Ensembl=ENSLOCG00000004468.1|UniProtKB=W5MAE0 W5MAE0 PTHR45841:SF1 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 LEPOC|Ensembl=ENSLOCG00000011569.1|UniProtKB=W5N0Q7 W5N0Q7 PTHR46091:SF1 BLR7054 PROTEIN ALL-TRANS-RETINOL 13,14-REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 retinoid metabolic process#GO:0001523;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;retinol metabolic process#GO:0042572;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;diterpenoid metabolic process#GO:0016101;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;terpenoid metabolic process#GO:0006721;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015320.1|UniProtKB=W5NDZ3 W5NDZ3 PTHR11969:SF18 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012482.1|UniProtKB=W5N422 W5N422 PTHR23206:SF8 MASK PROTEIN ANKYRIN REPEAT AND KH DOMAIN-CONTAINING 1 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003218.1|UniProtKB=W5M5Z6 W5M5Z6 PTHR11062:SF97 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 acetylglucosaminyltransferase activity#GO:0008375;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015677.1|UniProtKB=W5NF90 W5NF90 PTHR10338:SF14 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H2 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017200.1|UniProtKB=W5NKV4 W5NKV4 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012189.1|UniProtKB=W5N2Z5 W5N2Z5 PTHR24027:SF91 CADHERIN-23 CADHERIN-7 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000013505.1|UniProtKB=W5N7P0 W5N7P0 PTHR12619:SF2 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005866.1|UniProtKB=W5MFE2 W5MFE2 PTHR15887:SF1 TRANSMEMBRANE PROTEIN 69 TRANSMEMBRANE PROTEIN 69 LEPOC|Ensembl=ENSLOCG00000010450.1|UniProtKB=W5MWS7 W5MWS7 PTHR23220:SF5 INTEGRIN ALPHA INTEGRIN ALPHA-8 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011205.1|UniProtKB=W5MZF9 W5MZF9 PTHR14949:SF46 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 SCHWANN CELL-SPECIFIC EGF-LIKE REPEAT AUTOCRINE FACTOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;heart development#GO:0007507;signal transduction#GO:0007165;left/right pattern formation#GO:0060972;circulatory system development#GO:0072359;animal organ development#GO:0048513;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;system development#GO:0048731;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;blood vessel development#GO:0001568;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000017242.1|UniProtKB=W5NL17 W5NL17 PTHR18945:SF757 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000010133.1|UniProtKB=W5MVL4 W5MVL4 PTHR23119:SF57 DISCS LARGE PROTEIN SCRIBBLE HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 endosomal transport#GO:0016197;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;plasma membrane region#GO:0098590;postsynapse#GO:0098794;adherens junction#GO:0005912;basal part of cell#GO:0045178;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008164.1|UniProtKB=W5MNF6 W5MNF6 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000011893.1|UniProtKB=W5N1W6 W5N1W6 PTHR47522:SF2 SALVADOR FAMILY WW DOMAIN-CONTAINING PROTEIN 1 PROTEIN SALVADOR HOMOLOG 1 positive regulation of apoptotic process#GO:0043065;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;hippo signaling#GO:0035329;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002527.1|UniProtKB=W5M3L3 W5M3L3 PTHR11035:SF17 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 2 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000002855.1|UniProtKB=W5M4P6 W5M4P6 PTHR23507:SF3 ZGC:174356 THYMIC STROMAL COTRANSPORTER HOMOLOG transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010887.1|UniProtKB=W5MY91 W5MY91 PTHR47958:SF11 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX4-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;cellular process#GO:0009987;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000009130.1|UniProtKB=W5MRX3 W5MRX3 PTHR19857:SF8 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN LEPOC|Ensembl=ENSLOCG00000011017.1|UniProtKB=W5MYQ8 W5MYQ8 PTHR21436:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 LEPOC|Ensembl=ENSLOCG00000009831.1|UniProtKB=W5MUH0 W5MUH0 PTHR10783:SF103 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED SOLUTE CARRIER FAMILY 53 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;alcohol binding#GO:0043178 cellular response to stimulus#GO:0051716;transport#GO:0006810;cell communication#GO:0007154;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;phosphate ion transport#GO:0006817;cellular response to starvation#GO:0009267;response to stress#GO:0006950;establishment of localization#GO:0051234;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;inorganic anion transport#GO:0015698;cellular response to extracellular stimulus#GO:0031668 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005831.1|UniProtKB=W5MFB3 W5MFB3 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015792.1|UniProtKB=W5NFN2 W5NFN2 PTHR10333:SF103 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003400.1|UniProtKB=W5M6L8 W5M6L8 PTHR23192:SF31 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011877.1|UniProtKB=W5N1X9 W5N1X9 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN 4-RELATED microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000020971.1|UniProtKB=Q8HQN3 Q8HQN3 ND1 PTHR11432:SF3 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009534.1|UniProtKB=W5MTF5 W5MTF5 PTHR10543:SF57 BETA-CAROTENE DIOXYGENASE RETINOID ISOMEROHYDROLASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;isomerase activity#GO:0016853;oxidoreductase activity#GO:0016491 retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;isoprenoid catabolic process#GO:0008300;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;isoprenoid biosynthetic process#GO:0008299;diterpenoid metabolic process#GO:0016101;pigment biosynthetic process#GO:0046148;catabolic process#GO:0009056;carotenoid biosynthetic process#GO:0016117;terpenoid biosynthetic process#GO:0016114;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;terpenoid metabolic process#GO:0006721;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011644.1|UniProtKB=W5N114 W5N114 PTHR10672:SF4 ADDUCIN ALPHA-ADDUCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of epithelial cell differentiation#GO:0030856;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;positive regulation of developmental process#GO:0051094;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of developmental process#GO:0050793;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;adherens junction#GO:0005912;postsynapse#GO:0098794;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003663.1|UniProtKB=W5M7L2 W5M7L2 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000002221.1|UniProtKB=W5M2J7 W5M2J7 PTHR15673:SF2 IQ CALMODULIN-BINDING MOTIF CONTAINING PROTEIN 1 IQ CALMODULIN-BINDING MOTIF-CONTAINING PROTEIN 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000010306.1|UniProtKB=W5MW70 W5MW70 PTHR23503:SF130 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2 (FACILITATED GLUCOSE TRANSPORTER), MEMBER 9-LIKE 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010949.1|UniProtKB=W5MYH4 W5MYH4 PTHR14845:SF5 COILED-COIL DOMAIN-CONTAINING 166 BASAL BODY-ORIENTATION FACTOR 1 LEPOC|Ensembl=ENSLOCG00000014737.1|UniProtKB=W5NBY3 W5NBY3 ZMYM3 PTHR45736:SF3 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 3 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014671.1|UniProtKB=W5NBQ3 W5NBQ3 CSTPP1 PTHR34252:SF1 UPF0705 PROTEIN C11ORF49 CENTRIOLAR SATELLITE-ASSOCIATED TUBULIN POLYGLUTAMYLASE COMPLEX REGULATOR 1 LEPOC|Ensembl=ENSLOCG00000006051.1|UniProtKB=W5MG02 W5MG02 PTHR10869:SF223 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-3 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001306.1|UniProtKB=W5LZC8 W5LZC8 PTHR11846:SF11 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 LEPOC|Ensembl=ENSLOCG00000001575.1|UniProtKB=W5M0A2 W5M0A2 FOXJ3 PTHR46078:SF2 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000013766.1|UniProtKB=W5N8N4 W5N8N4 PTHR18945:SF893 NEUROTRANSMITTER GATED ION CHANNEL CHOLINERGIC RECEPTOR, NICOTINIC, BETA 1 (MUSCLE)-LIKE monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008694.1|UniProtKB=W5MQC4 W5MQC4 PTHR48092:SF19 KNIRPS-RELATED PROTEIN-RELATED MINERALOCORTICOID RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010480.1|UniProtKB=W5MWT8 W5MWT8 PTHR15510:SF5 SPERM-ASSOCIATED ANTIGEN 8 SPERM-ASSOCIATED ANTIGEN 8 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001792.1|UniProtKB=W5M118 W5M118 PTHR42738:SF18 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;branched-chain amino acid metabolic process#GO:0009081;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000013891.1|UniProtKB=W5N918 W5N918 PTHR15333:SF2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 LEPOC|Ensembl=ENSLOCG00000007611.1|UniProtKB=W5MLH5 W5MLH5 PTHR31993:SF5 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003514.1|UniProtKB=W5M704 W5M704 PTHR11848:SF135 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 7 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06901;Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06687;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000015120.1|UniProtKB=W5ND97 W5ND97 PTHR15950:SF23 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN SI:CH73-52F15.5-RELATED transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011379.1|UniProtKB=W5N026 W5N026 PTHR24229:SF42 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 3 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000012647.1|UniProtKB=W5N4L4 W5N4L4 PTHR23302:SF66 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004420.1|UniProtKB=W5MA97 W5MA97 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000178.1|UniProtKB=W5LVP1 W5LVP1 PTHR11866:SF5 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER THROMBOXANE A2 RECEPTOR regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;system process#GO:0003008;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of system process#GO:0044057;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002295.1|UniProtKB=W5M2T2 W5M2T2 PTHR11430:SF63 LIPOCALIN LOC555483 PROTEIN-RELATED transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000011070.1|UniProtKB=W5MYY9 W5MYY9 PTHR18952:SF208 CARBONIC ANHYDRASE CARBONIC ANHYDRASE XA-RELATED carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000006996.1|UniProtKB=W5MJB3 W5MJB3 PTHR13213:SF2 MYB-BINDING PROTEIN 1A FAMILY MEMBER MYB-BINDING PROTEIN 1A intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016035.1|UniProtKB=W5NGJ4 W5NGJ4 PTHR13902:SF48 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013431.1|UniProtKB=W5N7G1 W5N7G1 UNC13C PTHR10480:SF2 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG C syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;transport#GO:0006810;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;establishment of organelle localization#GO:0051656;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;vesicle localization#GO:0051648;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;synaptic transmission, glutamatergic#GO:0035249;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;neuromuscular junction#GO:0031594;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Munc13#P05773 LEPOC|Ensembl=ENSLOCG00000007904.1|UniProtKB=W5MMI9 W5MMI9 PTHR10681:SF161 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-2 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cellular process#GO:0009987;cell activation#GO:0001775;immune system process#GO:0002376;response to stimulus#GO:0050896;detoxification#GO:0098754;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;response to toxic substance#GO:0009636;response to reactive oxygen species#GO:0000302;cellular response to stress#GO:0033554;leukocyte activation#GO:0045321;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010571.1|UniProtKB=W5MX43 W5MX43 PTHR11280:SF8 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE ISOMERASE 1 identical protein binding#GO:0042802;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;protein binding#GO:0005515;deaminase activity#GO:0019239;binding#GO:0005488;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;amino sugar catabolic process#GO:0046348;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;amide metabolic process#GO:0043603;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 LEPOC|Ensembl=ENSLOCG00000002320.1|UniProtKB=W5M314 W5M314 PTHR11654:SF603 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 2 amide transmembrane transporter activity#GO:0042887;oligopeptide transmembrane transporter activity#GO:0035673;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;oligopeptide transport#GO:0006857;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;nitrogen compound transport#GO:0071705;dipeptide transport#GO:0042938;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;import into cell#GO:0098657 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007282.1|UniProtKB=W5MKA6 W5MKA6 PTHR18945:SF74 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000008664.1|UniProtKB=W5MQ84 W5MQ84 PTHR11909:SF78 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014789.1|UniProtKB=W5NC57 W5NC57 PTHR12112:SF12 BNIP - RELATED BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 2 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000962.1|UniProtKB=W5LY65 W5LY65 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003165.1|UniProtKB=W5M5T1 W5M5T1 PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US15M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005989.1|UniProtKB=W5MFS9 W5MFS9 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011651.1|UniProtKB=W5N1A0 W5N1A0 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN 4-RELATED microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000015106.1|UniProtKB=W5ND85 W5ND85 PTHR44809:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC1 LEPOC|Ensembl=ENSLOCG00000004516.1|UniProtKB=W5MAK6 W5MAK6 PTHR21616:SF2 CENTROSOME SPINDLE POLE ASSOCIATED PROTEIN CENTROSOME AND SPINDLE POLE-ASSOCIATED PROTEIN 1 centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000017087.1|UniProtKB=W5NKF7 W5NKF7 PTHR44086:SF10 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 thiosulfate sulfurtransferase activity#GO:0004792;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011501.1|UniProtKB=W5N0H3 W5N0H3 PTHR19368:SF15 XLR/SCP3/FAM9 XLR_SYCP3_FAM9 DOMAIN-CONTAINING PROTEIN germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;developmental process#GO:0032502;spermatid differentiation#GO:0048515;cellular process#GO:0009987;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 LEPOC|Ensembl=ENSLOCG00000010108.1|UniProtKB=W5MVH0 W5MVH0 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003912.1|UniProtKB=W5M8F9 W5M8F9 PTHR23349:SF62 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST MUSCULIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 skeletal muscle organ development#GO:0060538;muscle organ development#GO:0007517;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;muscle tissue development#GO:0060537;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000013452.1|UniProtKB=W5N7I6 W5N7I6 PTHR11827:SF98 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002629.1|UniProtKB=W5M3Y5 W5M3Y5 PTHR19143:SF256 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 4 enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;triglyceride homeostasis#GO:0070328;chemical homeostasis#GO:0048878 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005843.1|UniProtKB=W5MF97 W5MF97 IPP PTHR24412:SF35 KELCH PROTEIN ACTIN-BINDING PROTEIN IPP scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012507.1|UniProtKB=W5N440 W5N440 PTHR15301:SF11 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 1 PROTEIN sterol metabolic process#GO:0016125;cellular localization#GO:0051641;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;cholesterol metabolic process#GO:0008203;lipid biosynthetic process#GO:0008610;regulation of biological process#GO:0050789;steroid metabolic process#GO:0008202;regulation of cellular response to stress#GO:0080135;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;protein localization to endoplasmic reticulum#GO:0070972;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;alcohol metabolic process#GO:0006066;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;primary metabolic process#GO:0044238;protein localization#GO:0008104;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;negative regulation of signal transduction#GO:0009968;small molecule biosynthetic process#GO:0044283;cellular response to stress#GO:0033554;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;cellular response to lipid#GO:0071396;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;cellular response to organic cyclic compound#GO:0071407;cellular response to insulin stimulus#GO:0032869;protein localization to organelle#GO:0033365;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;SREBP signaling pathway#GO:0032933;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;sterol biosynthetic process#GO:0016126 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000003403.1|UniProtKB=W5M6M1 W5M6M1 PTHR23034:SF2 GLUTAMATE-RICH PROTEIN 3 GLUTAMATE-RICH PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000001630.1|UniProtKB=W5M0G8 W5M0G8 UBXN4 PTHR46424:SF1 UBX DOMAIN-CONTAINING PROTEIN 4 UBX DOMAIN-CONTAINING PROTEIN 4 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001107.1|UniProtKB=W5LYN6 W5LYN6 PTHR16294:SF4 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 LEPOC|Ensembl=ENSLOCG00000007570.1|UniProtKB=W5MLC8 W5MLC8 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010730.1|UniProtKB=W5MXN4 W5MXN4 PTHR47148:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003818.1|UniProtKB=W5M845 W5M845 PTHR17554:SF2 TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 negative regulation of gene expression#GO:0010629;regulation of leukocyte mediated cytotoxicity#GO:0001910;macrophage activation#GO:0042116;regulation of cellular component organization#GO:0051128;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;regulation of multicellular organismal process#GO:0051239;negative regulation of metabolic process#GO:0009892;cell activation involved in immune response#GO:0002263;negative regulation of leukocyte activation#GO:0002695;myeloid leukocyte activation#GO:0002274;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;regulation of cellular process#GO:0050794;regulation of cell killing#GO:0031341;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;inflammatory response#GO:0006954;negative regulation of multicellular organismal process#GO:0051241;macrophage activation involved in immune response#GO:0002281;neutrophil activation#GO:0042119;regulation of biosynthetic process#GO:0009889;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of lymphocyte activation#GO:0051249;immune effector process#GO:0002252;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of cell population proliferation#GO:0042127;negative regulation of biosynthetic process#GO:0009890;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;negative regulation of cell activation#GO:0050866;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of immune effector process#GO:0002697;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of cellular biosynthetic process#GO:0031326;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of cellular component organization#GO:0051130;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;regulation of B cell proliferation#GO:0030888 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002676.1|UniProtKB=W5M431 W5M431 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013166.1|UniProtKB=W5N6G1 W5N6G1 PTHR19872:SF7 UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN F-BOX AND WD REPEAT DOMAIN CONTAINING PROTEIN 10B-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012740.1|UniProtKB=W5N4X1 W5N4X1 ADSSL1 PTHR11846:SF2 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 1 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 LEPOC|Ensembl=ENSLOCG00000000377.1|UniProtKB=W5LWA3 W5LWA3 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27-LIKE serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015456.1|UniProtKB=W5NEG4 W5NEG4 PTHR46415:SF1 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 DCC-INTERACTING PROTEIN 13-BETA biological regulation#GO:0065007;regulation of biological process#GO:0050789;signaling#GO:0023052 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001505.1|UniProtKB=W5M033 W5M033 CDK5RAP1 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000013328.1|UniProtKB=W5N723 W5N723 PTHR46006:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001776.1|UniProtKB=W5M0Z2 W5M0Z2 PTHR10165:SF14 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007531.1|UniProtKB=W5ML74 W5ML74 PTHR24049:SF1 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 1 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;establishment or maintenance of bipolar cell polarity#GO:0061245 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012585.1|UniProtKB=W5N4E8 W5N4E8 PTHR13780:SF122 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 LEPOC|Ensembl=ENSLOCG00000009992.1|UniProtKB=W5MV27 W5MV27 PTHR18934:SF113 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE TDRD9 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000011750.1|UniProtKB=W5N1D7 W5N1D7 SKIDA1 PTHR23187:SF4 FLJ44216 PROTEIN-RELATED SKI_DACH DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010849.1|UniProtKB=W5MY40 W5MY40 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015213.1|UniProtKB=W5NDL1 W5NDL1 PTHR11964:SF73 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 LEPOC|Ensembl=ENSLOCG00000013531.1|UniProtKB=W5N7S8 W5N7S8 PTHR24388:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280D sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012848.1|UniProtKB=W5N5A8 W5N5A8 PTHR23302:SF35 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 3 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001579.1|UniProtKB=W5M0A7 W5M0A7 CLEC18A PTHR10334:SF521 CYSTEINE-RICH SECRETORY PROTEIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017027.1|UniProtKB=W5NK98 W5NK98 PTHR11477:SF10 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN PHD FINGER PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011846.1|UniProtKB=W5N1R4 W5N1R4 PTHR46618:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 3 ARMADILLO REPEAT-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000010286.1|UniProtKB=W5MW36 W5MW36 PTHR48051:SF16 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000239.1|UniProtKB=W5LVV8 W5LVV8 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011663.1|UniProtKB=W5N120 W5N120 PTHR13166:SF7 PROTEIN C6ORF149 LYR MOTIF-CONTAINING PROTEIN 4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003619.1|UniProtKB=W5M7G0 W5M7G0 PTHR24390:SF242 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016136.1|UniProtKB=W5NGX5 W5NGX5 PTHR47056:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;positive regulation of cell migration#GO:0030335;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;positive regulation of locomotion#GO:0040017;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012562.1|UniProtKB=W5N4A8 W5N4A8 XRCC2 PTHR46644:SF2 DNA REPAIR PROTEIN XRCC2 DNA REPAIR PROTEIN XRCC2 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012235.1|UniProtKB=W5N341 W5N341 PTHR20854:SF44 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;organic hydroxy compound metabolic process#GO:1901615;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;signaling#GO:0023052;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001255.1|UniProtKB=W5LZD1 W5LZD1 PTHR13817:SF77 TITIN CONTACTIN-1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011658.1|UniProtKB=W5N116 W5N116 PTHR11360:SF26 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 3 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012964.1|UniProtKB=W5N5S1 W5N5S1 PTHR24033:SF193 EGF-LIKE DOMAIN-CONTAINING PROTEIN NETRIN-G1-RELATED Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 LEPOC|Ensembl=ENSLOCG00000015285.1|UniProtKB=W5NDU6 W5NDU6 PTHR24068:SF152 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein K63-linked ubiquitination#GO:0070534;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 LEPOC|Ensembl=ENSLOCG00000005476.1|UniProtKB=W5ME08 W5ME08 PTHR13817:SF80 TITIN INACTIVE TYROSINE-PROTEIN KINASE 7 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009869.1|UniProtKB=W5MUK2 W5MUK2 PTHR12570:SF7 FAMILY NOT NAMED MAGNESIUM TRANSPORTER NIPA4 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002291.1|UniProtKB=W5M2S0 W5M2S0 PTHR11537:SF167 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 4 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000010953.1|UniProtKB=W5MYI0 W5MYI0 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010554.1|UniProtKB=W5MX24 W5MX24 PTHR15950:SF16 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 3 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000007158.1|UniProtKB=W5MJV2 W5MJV2 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000011630.1|UniProtKB=W5N0Y2 W5N0Y2 PTHR24232:SF105 G-PROTEIN COUPLED RECEPTOR URACIL NUCLEOTIDE_CYSTEINYL LEUKOTRIENE RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017062.1|UniProtKB=W5NKE2 W5NKE2 COL19A1 PTHR24023:SF938 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000002876.1|UniProtKB=W5M4S5 W5M4S5 PTHR46600:SF2 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005179.1|UniProtKB=W5MCZ5 W5MCZ5 PTHR10286:SF43 INORGANIC PYROPHOSPHATASE INORGANIC DIPHOSPHATASE hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 pyrophosphatase#PC00196 LEPOC|Ensembl=ENSLOCG00000003384.1|UniProtKB=W5M6K1 W5M6K1 PTHR10125:SF12 P2X PURINOCEPTOR P2X PURINOCEPTOR 5 monoatomic cation channel activity#GO:0005261;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009980.1|UniProtKB=W5MUZ5 W5MUZ5 PTHR12920:SF3 RYBP AND YAF2-RELATED RING1 AND YY1-BINDING PROTEIN molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000012349.1|UniProtKB=W5N3K2 W5N3K2 PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014760.1|UniProtKB=W5NC17 W5NC17 PTHR46448:SF2 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;skeletal system development#GO:0001501;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;peptidyl-tyrosine modification#GO:0018212;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000016768.1|UniProtKB=W5NJB8 W5NJB8 PTHR10970:SF1 CLUSTERIN CLUSTERIN protein binding#GO:0005515;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CCKR signaling map#P06959>CLU#G06991;CCKR signaling map#P06959>CLU#G07284;CCKR signaling map#P06959>CLU#P07069 LEPOC|Ensembl=ENSLOCG00000017455.1|UniProtKB=W5NLQ1 W5NLQ1 PTHR26451:SF847 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011622.1|UniProtKB=W5N0X4 W5N0X4 PTHR45652:SF23 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000015121.1|UniProtKB=W5NDA1 W5NDA1 PTHR24240:SF67 OPSIN TELEOST MULTIPLE TISSUE OPSIN 3A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008115.1|UniProtKB=W5MN96 W5MN96 PTHR24161:SF109 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 4B protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012586.1|UniProtKB=W5N4D6 W5N4D6 PTHR28630:SF31 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2A LEPOC|Ensembl=ENSLOCG00000002791.1|UniProtKB=W5M4H4 W5M4H4 PTHR19282:SF504 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008743.1|UniProtKB=W5MQI3 W5MQI3 PTHR11890:SF6 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR 1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012579.1|UniProtKB=W5N4C6 W5N4C6 PTHR10129:SF15 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of epithelial cell differentiation#GO:0030856;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000015798.1|UniProtKB=W5NFP3 W5NFP3 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000012965.1|UniProtKB=W5N5R8 W5N5R8 PTHR14159:SF0 ATAXIN-3-RELATED ATAXIN-3-RELATED cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015660.1|UniProtKB=W5NF69 W5NF69 PTHR15944:SF3 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000002377.1|UniProtKB=W5M378 W5M378 PTHR10856:SF20 CORONIN CORONIN-7 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011095.1|UniProtKB=W5MZ20 W5MZ20 PTHR15893:SF0 RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011216.1|UniProtKB=W5MZG7 W5MZG7 PTHR11046:SF25 OLIGORIBONUCLEASE, MITOCHONDRIAL SUBFAMILY NOT NAMED endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005318.1|UniProtKB=W5MDE6 W5MDE6 LKAAEAR1 PTHR35665:SF1 PROTEIN LKAAEAR1 PROTEIN LKAAEAR1 LEPOC|Ensembl=ENSLOCG00000003187.1|UniProtKB=W5M5V9 W5M5V9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001977.1|UniProtKB=W5M1N0 W5M1N0 PTHR24126:SF14 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANK_REP_REGION DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013334.1|UniProtKB=W5N728 W5N728 PTHR10901:SF15 TROPOMODULIN TROPOMODULIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;non-membrane-bounded organelle assembly#GO:0140694;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002255.1|UniProtKB=W5M2M4 W5M2M4 PTHR15970:SF7 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 2 transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003878.1|UniProtKB=W5M8D0 W5M8D0 PTHR24230:SF31 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007176.1|UniProtKB=W5MJZ6 W5MJZ6 PTHR11474:SF124 TYROSINASE FAMILY MEMBER TYROSINASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;secondary metabolic process#GO:0019748;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;secondary metabolite biosynthetic process#GO:0044550;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016942.1|UniProtKB=W5NJY4 W5NJY4 PTHR24068:SF168 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004143.1|UniProtKB=W5M9A0 W5M9A0 PTHR12150:SF13 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED METHYLTRANSFERASE C9ORF114-RELATED methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000000889.1|UniProtKB=W5LXY2 W5LXY2 PTHR10265:SF44 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1C negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of cell cycle#GO:0045786;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000001040.1|UniProtKB=W5LYH6 W5LYH6 PTHR19134:SF433 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ALPHA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009307.1|UniProtKB=W5MSK6 W5MSK6 PTHR14304:SF14 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006723.1|UniProtKB=W5MIB8 W5MIB8 PTHR18884:SF66 SEPTIN SEPTIN-12 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000013436.1|UniProtKB=W5N7F5 W5N7F5 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;regulation of primary metabolic process#GO:0080090;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007114.1|UniProtKB=W5MJQ2 W5MJQ2 PTHR43599:SF3 MULTIFUNCTIONAL PROTEIN ADE2 SI:DKEY-6E2.2 LEPOC|Ensembl=ENSLOCG00000017744.1|UniProtKB=W5NMI9 W5NMI9 PTHR24123:SF105 ANKYRIN REPEAT-CONTAINING CARD- AND ANK-DOMAIN CONTAINING INFLAMMASOME ADAPTER PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015898.1|UniProtKB=W5NG17 W5NG17 PTHR12001:SF44 GERANYLGERANYL PYROPHOSPHATE SYNTHASE GERANYLGERANYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;cellular lipid metabolic process#GO:0044255;isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 LEPOC|Ensembl=ENSLOCG00000000940.1|UniProtKB=W5LY44 W5LY44 BSPRY PTHR24103:SF568 E3 UBIQUITIN-PROTEIN LIGASE TRIM B BOX AND SPRY DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000619.1|UniProtKB=W5LX22 W5LX22 PTHR11929:SF198 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 11 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007280.1|UniProtKB=W5MKA7 W5MKA7 PTHR15708:SF14 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED METASTASIS SUPPRESSOR 1 ISOFORM X1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008481.1|UniProtKB=W5MPL8 W5MPL8 PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017904.1|UniProtKB=W5NMZ8 W5NMZ8 PTHR24241:SF1 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 22 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012089.1|UniProtKB=W5N2L9 W5N2L9 PTHR14753:SF3 F-BOX ONLY PROTEIN 38 F-BOX ONLY PROTEIN 38 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015837.1|UniProtKB=W5NFU8 W5NFU8 PTHR15711:SF7 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009058.1|UniProtKB=W5MRM7 W5MRM7 PTHR34920:SF1 B-CELL LYMPHOMA/LEUKEMIA 10 B-CELL LYMPHOMA_LEUKEMIA 10 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;NF-kappaB binding#GO:0051059;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;transcription factor binding#GO:0008134;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;DNA-binding transcription factor binding#GO:0140297;kinase activator activity#GO:0019209;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein kinase binding#GO:0019901 positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009384.1|UniProtKB=W5MSW8 W5MSW8 PTHR45981:SF4 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF8 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;MHC protein binding#GO:0042287;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;immune response#GO:0006955;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;antigen processing and presentation#GO:0019882;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000014040.1|UniProtKB=W5N9J6 W5N9J6 PDCL2 PTHR45809:SF1 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000000519.1|UniProtKB=W5LWR6 W5LWR6 PTHR22055:SF0 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013875.1|UniProtKB=W5N902 W5N902 PTHR24040:SF3 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN SEX HORMONE-BINDING GLOBULIN lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 LEPOC|Ensembl=ENSLOCG00000001808.1|UniProtKB=W5M144 W5M144 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009521.1|UniProtKB=W5MTE0 W5MTE0 PTHR24023:SF918 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000018335.1|UniProtKB=W5NP77 W5NP77 NHLRC1 PTHR24104:SF47 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE NHLRC1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013881.1|UniProtKB=W5N910 W5N910 PTHR24355:SF23 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012320.1|UniProtKB=W5N3H3 W5N3H3 PTHR43775:SF7 FATTY ACID SYNTHASE FATTY ACID SYNTHASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000003959.1|UniProtKB=W5M8M1 W5M8M1 PTHR19282:SF3 TETRASPANIN TETRASPANIN-31 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014632.1|UniProtKB=W5NBK6 W5NBK6 PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004633.1|UniProtKB=W5MAZ2 W5MAZ2 COQ10A PTHR12901:SF8 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG A, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009012.1|UniProtKB=W5MRI0 W5MRI0 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000014110.1|UniProtKB=W5N9S4 W5N9S4 PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006351.1|UniProtKB=W5MH11 W5MH11 PTHR11802:SF434 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010909.1|UniProtKB=W5MYD5 W5MYD5 PTHR24095:SF83 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014298.1|UniProtKB=W5NAE4 W5NAE4 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015980.1|UniProtKB=W5NGB7 W5NGB7 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000004343.1|UniProtKB=W5M9X9 W5M9X9 PTHR11311:SF16 SPONDIN SPONDIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008012.1|UniProtKB=W5MMX1 W5MMX1 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 POST-GPI ATTACHMENT TO PROTEINS FACTOR 2 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002241.1|UniProtKB=W5M2J9 W5M2J9 PTHR12753:SF1 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007863.1|UniProtKB=W5MME6 W5MME6 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017471.1|UniProtKB=W5NLR7 W5NLR7 PTHR24228:SF8 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-2 ANGIOTENSIN II RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;defense response#GO:0006952;signaling#GO:0023052;inflammatory response#GO:0006954 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008847.1|UniProtKB=W5MQW3 W5MQW3 GPR89B PTHR15948:SF0 G-PROTEIN COUPLED RECEPTOR 89-RELATED GOLGI PH REGULATOR A-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015584.1|UniProtKB=W5NEX7 W5NEX7 PTHR13285:SF20 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000011932.1|UniProtKB=W5N215 W5N215 PTHR15725:SF14 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11A RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011350.1|UniProtKB=W5MZY5 W5MZY5 PTHR23235:SF173 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018170.1|UniProtKB=W5NNR2 W5NNR2 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006999.1|UniProtKB=W5MJB4 W5MJB4 PTHR18884:SF117 SEPTIN SEPTIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell division#GO:0051301;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;plasma membrane bounded cell projection assembly#GO:0120031;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004373.1|UniProtKB=W5MA18 W5MA18 PTHR45810:SF17 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001089.1|UniProtKB=W5LYM2 W5LYM2 KCNMB2 PTHR10258:SF5 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ligand-gated monoatomic cation channel activity#GO:0099094;channel regulator activity#GO:0016247;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000000253.1|UniProtKB=W5LVX0 W5LVX0 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005749.1|UniProtKB=W5MF02 W5MF02 PTHR12207:SF33 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 8 PRECURSOR cellular anatomical entity#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011101.1|UniProtKB=W5MZ29 W5MZ29 PTHR16453:SF9 WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER GATOR COMPLEX PROTEIN MIOS cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010853.1|UniProtKB=W5MY43 W5MY43 PTHR28546:SF2 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;transport#GO:0006810;protein-containing complex assembly#GO:0065003;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007752.1|UniProtKB=W5MM03 W5MM03 PTHR16983:SF10 UPAR/LY6 DOMAIN-CONTAINING PROTEIN PROTEIN QUIVER protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003719.1|UniProtKB=W5M7R1 W5M7R1 PTHR20899:SF1 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000000696.1|UniProtKB=W5LXB3 W5LXB3 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004181.1|UniProtKB=W5M9J1 W5M9J1 PTHR13723:SF41 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 8 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013054.1|UniProtKB=W5N616 W5N616 PTHR15074:SF7 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING DOMAIN PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014502.1|UniProtKB=W5NB53 W5NB53 PTHR43097:SF4 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 LEPOC|Ensembl=ENSLOCG00000004822.1|UniProtKB=W5MBM7 W5MBM7 BBLN PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 BUBLIN COILED-COIL PROTEIN LEPOC|Ensembl=ENSLOCG00000014617.1|UniProtKB=W5NBI4 W5NBI4 PTHR15711:SF15 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell development#GO:0048468;establishment or maintenance of cell polarity#GO:0007163;establishment of cell polarity#GO:0030010;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;epithelium development#GO:0060429;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell morphogenesis#GO:0000902;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015493.1|UniProtKB=W5NEK8 W5NEK8 PTHR24044:SF380 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 LEPOC|Ensembl=ENSLOCG00000014369.1|UniProtKB=W5NAN5 W5NAN5 PTHR22802:SF351 C-TYPE LECTIN SUPERFAMILY MEMBER IMMUNE-RELATED LECTIN-LIKE RECEPTOR 1-RELATED membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010951.1|UniProtKB=W5MYH8 W5MYH8 PTHR46127:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008066.1|UniProtKB=W5MN51 W5MN51 PTHR24020:SF49 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVIII) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000016493.1|UniProtKB=W5NIB4 W5NIB4 PTHR45813:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G-PROTEIN COUPLED RECEPTOR F3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014074.1|UniProtKB=W5N9N6 W5N9N6 PTHR10361:SF41 SODIUM-BILE ACID COTRANSPORTER SODIUM_BILE ACID COTRANSPORTER 4 secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004786.1|UniProtKB=W5MBK1 W5MBK1 PTHR46360:SF1 DISKS LARGE HOMOLOG 5 DISKS LARGE HOMOLOG 5 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000306.1|UniProtKB=W5LW26 W5LW26 PTHR11453:SF37 ANION EXCHANGE PROTEIN ELECTRONEUTRAL SODIUM BICARBONATE EXCHANGER 1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017039.1|UniProtKB=W5NKA2 W5NKA2 PTHR15036:SF93 PIKACHURIN-LIKE PROTEIN EYS PROTEIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012408.1|UniProtKB=W5N3S8 W5N3S8 PTHR15036:SF43 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN 1 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009576.1|UniProtKB=W5MTJ3 W5MTJ3 PTHR24124:SF5 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR ZETA regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012750.1|UniProtKB=W5N4Y3 W5N4Y3 PTHR16134:SF32 F-BOX/TPR REPEAT PROTEIN POF3 S-PHASE KINASE-ASSOCIATED PROTEIN 2 mitotic cell cycle phase transition#GO:0044772;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;cell cycle G2/M phase transition#GO:0044839 SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011656.1|UniProtKB=W5N112 W5N112 PPP1R3G PTHR12307:SF7 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000013119.1|UniProtKB=W5N698 W5N698 FADS6 PTHR19353:SF13 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005112.1|UniProtKB=W5MCP4 W5MCP4 PTHR13006:SF8 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 SLC2A4 REGULATOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000013224.1|UniProtKB=W5N6N1 W5N6N1 PTHR11241:SF0 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE cation binding#GO:0043169;pyrophosphatase activity#GO:0016462;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 LEPOC|Ensembl=ENSLOCG00000014482.1|UniProtKB=W5NB30 W5NB30 PTHR10338:SF115 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003506.1|UniProtKB=W5M6Z6 W5M6Z6 PTHR24124:SF8 ANKYRIN REPEAT FAMILY A OCA DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015870.1|UniProtKB=W5NFY1 W5NFY1 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011439.1|UniProtKB=W5N0A3 W5N0A3 PTHR46406:SF1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003868.1|UniProtKB=W5M8C2 W5M8C2 PTHR46449:SF5 ZGC:158260 FAMILY WITH SEQUENCE SIMILARITY 47 MEMBER E positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;epigenetic regulation of gene expression#GO:0040029;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011236.1|UniProtKB=W5MZJ4 W5MZJ4 PTHR12107:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;channel regulator activity#GO:0016247;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;system process#GO:0003008;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;receptor-mediated endocytosis#GO:0006898;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;protein localization to organelle#GO:0033365;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;positive regulation of biological process#GO:0048518;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;vacuolar transport#GO:0007034;endocytosis#GO:0006897;protein localization to vacuole#GO:0072665;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;positive regulation of synaptic transmission#GO:0050806;import into cell#GO:0098657;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 LEPOC|Ensembl=ENSLOCG00000018158.1|UniProtKB=W5NNQ0 W5NNQ0 PTHR24228:SF67 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR APELIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 heart development#GO:0007507;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015856.1|UniProtKB=W5NFW2 W5NFW2 PTHR46216:SF3 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER PROSAPOSIN RECEPTOR GPR37 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 LEPOC|Ensembl=ENSLOCG00000006193.1|UniProtKB=W5MGI4 W5MGI4 PTHR14167:SF68 SH3 DOMAIN-CONTAINING DREBRIN-LIKE PROTEIN-RELATED cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011849.1|UniProtKB=W5N1R0 W5N1R0 PTHR32261:SF2 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000001134.1|UniProtKB=W5LYT8 W5LYT8 PTHR43655:SF7 ATP-DEPENDENT PROTEASE AFG3-LIKE PROTEIN 1 mitochondrial protein processing#GO:0034982;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;peptidase complex#GO:1905368;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011507.1|UniProtKB=W5N0I1 W5N0I1 PTHR21181:SF7 FAMILY NOT NAMED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890 membrane protein complex#GO:0098796;endosome#GO:0005768;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017042.1|UniProtKB=W5NKB2 W5NKB2 PTHR11339:SF361 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VON WILLEBRAND FACTOR response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;wound healing#GO:0042060;blood coagulation#GO:0007596;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;hemostasis#GO:0007599;coagulation#GO:0050817 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Blood coagulation#P00011>vWF#P00448 LEPOC|Ensembl=ENSLOCG00000013355.1|UniProtKB=W5N753 W5N753 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443 LEPOC|Ensembl=ENSLOCG00000018151.1|UniProtKB=W5NNP3 W5NNP3 PTHR46048:SF7 HYDROXYCARBOXYLIC ACID RECEPTOR 2 12-(S)-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID RECEPTOR G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001014.1|UniProtKB=W5LYG0 W5LYG0 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001501.1|UniProtKB=W5M005 W5M005 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 Methylcitrate cycle#P02754>Aconitase#P03028 LEPOC|Ensembl=ENSLOCG00000012498.1|UniProtKB=W5N425 W5N425 PTHR45803:SF1 SOX100B TRANSCRIPTION FACTOR SOX-9 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;central nervous system development#GO:0007417;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;negative regulation of metabolic process#GO:0009892;oligodendrocyte differentiation#GO:0048709;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;heart development#GO:0007507;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;epithelium development#GO:0060429;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;glial cell differentiation#GO:0010001;cell differentiation#GO:0030154;system development#GO:0048731;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;positive regulation of cell differentiation#GO:0045597;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;tissue morphogenesis#GO:0048729;biological regulation#GO:0065007;morphogenesis of an epithelium#GO:0002009;cartilage development#GO:0051216 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000008608.1|UniProtKB=W5MQ17 W5MQ17 PTHR11412:SF86 MACROGLOBULIN / COMPLEMENT COMPLEMENT C4-A-RELATED activation of immune response#GO:0002253;immune response#GO:0006955;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000017670.1|UniProtKB=W5NMB6 W5NMB6 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003916.1|UniProtKB=W5M8H4 W5M8H4 PTHR18934:SF271 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX40-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000000165.1|UniProtKB=W5LVM6 W5LVM6 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000013146.1|UniProtKB=W5N6D5 W5N6D5 PTHR12326:SF5 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1 LEPOC|Ensembl=ENSLOCG00000015771.1|UniProtKB=W5NFK6 W5NFK6 PTHR46917:SF1 MORN REPEAT-CONTAINING PROTEIN 2 MORN REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000018156.1|UniProtKB=W5NNP8 W5NNP8 PTHR45961:SF5 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000011811.1|UniProtKB=W5N1M7 W5N1M7 PTHR45652:SF9 GLIAL FIBRILLARY ACIDIC PROTEIN GLIAL FIBRILLARY ACIDIC PROTEIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of protein catabolic process#GO:0042176;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;regulation of metabolic process#GO:0019222;intermediate filament-based process#GO:0045103;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cell projection#GO:0042995;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000005755.1|UniProtKB=W5MEZ3 W5MEZ3 PTHR45960:SF1 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000003944.1|UniProtKB=W5M8K9 W5M8K9 PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A LEPOC|Ensembl=ENSLOCG00000015542.1|UniProtKB=W5NES2 W5NES2 PTHR20908:SF4 LD15586P SI:DKEY-5I3.5 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 LEPOC|Ensembl=ENSLOCG00000011550.1|UniProtKB=W5N0N7 W5N0N7 PTHR24232:SF22 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-4#P00461 LEPOC|Ensembl=ENSLOCG00000005005.1|UniProtKB=W5MCC1 W5MCC1 PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of response to external stimulus#GO:0032101;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;regulation of defense response#GO:0031347;biological regulation#GO:0065007;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006539.1|UniProtKB=W5MHP2 W5MHP2 PTHR43668:SF2 ALLANTOINASE ALLANTOINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydroorotase#P02928;Allantoin degradation#P02725>Allantoinase#P02822 LEPOC|Ensembl=ENSLOCG00000006695.1|UniProtKB=W5MI73 W5MI73 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001499.1|UniProtKB=W5M021 W5M021 PTHR23151:SF90 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017610.1|UniProtKB=W5NM56 W5NM56 PTHR31893:SF3 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151A LEPOC|Ensembl=ENSLOCG00000015339.1|UniProtKB=W5NE16 W5NE16 PTHR12522:SF2 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 703 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011447.1|UniProtKB=W5N0C0 W5N0C0 PTHR10241:SF20 LETHAL 2 GIANT LARVAE PROTEIN LLGL SCRIBBLE CELL POLARITY COMPLEX COMPONENT 2 nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;myosin binding#GO:0017022;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;binding#GO:0005488;syntaxin binding#GO:0019905;protein binding#GO:0005515;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;SNARE binding#GO:0000149 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of spindle orientation#GO:0051294;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of Notch signaling pathway#GO:0008593;Golgi to plasma membrane transport#GO:0006893;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;secretion by cell#GO:0032940;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001440.1|UniProtKB=W5LZT1 W5LZT1 FAM3B PTHR14592:SF2 UNCHARACTERIZED FAM3 PROTEIN FAM3B extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 LEPOC|Ensembl=ENSLOCG00000017747.1|UniProtKB=W5NMJ2 W5NMJ2 FOXD2 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004848.1|UniProtKB=W5MBR7 W5MBR7 PTHR24089:SF736 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009321.1|UniProtKB=W5MSL1 W5MSL1 PTHR20859:SF48 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008198.1|UniProtKB=W5MNJ5 W5MNJ5 PTHR12743:SF0 CYTOCHROME C1 HEME LYASE HOLOCYTOCHROME C-TYPE SYNTHASE lyase activity#GO:0016829;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000017094.1|UniProtKB=W5NKG4 W5NKG4 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013991.1|UniProtKB=W5N9D6 W5N9D6 TRMT9B PTHR13069:SF36 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA METHYLTRANSFERASE 9B-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003733.1|UniProtKB=W5M7X7 W5M7X7 PTHR45761:SF3 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-1 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008973.1|UniProtKB=W5MRC0 W5MRC0 PTHR11774:SF4 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein modification process#GO:0036211;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004028.1|UniProtKB=W5M8V2 W5M8V2 PTGR3 PTHR43677:SF3 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004665.1|UniProtKB=W5MB27 W5MB27 PTHR12183:SF36 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000012025.1|UniProtKB=W5N2D1 W5N2D1 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008982.1|UniProtKB=W5MRD7 W5MRD7 PTHR12263:SF2 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 2 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 ATP synthase#PC00002;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005849.1|UniProtKB=W5MFA7 W5MFA7 PTHR11347:SF23 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA' hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;system process#GO:0003008;cell communication#GO:0007154;nervous system process#GO:0050877;visual perception#GO:0007601;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000010666.1|UniProtKB=W5MXG1 W5MXG1 PTHR11746:SF150 O-METHYLTRANSFERASE ACETYLSEROTONIN O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;hormone biosynthetic process#GO:0042446;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;hormone metabolic process#GO:0042445;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016280.1|UniProtKB=W5NHH5 W5NHH5 FSHR PTHR24372:SF5 GLYCOPROTEIN HORMONE RECEPTOR FOLLICLE-STIMULATING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of adenylate cyclase activity#GO:0045762;reproductive system development#GO:0061458;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;rhythmic process#GO:0048511;cellular process involved in reproduction in multicellular organism#GO:0022412;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;hormone-mediated signaling pathway#GO:0009755;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;reproductive process#GO:0022414;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;male sex differentiation#GO:0046661;response to organic substance#GO:0010033;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular response to organic substance#GO:0071310;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;developmental process involved in reproduction#GO:0003006;response to stimulus#GO:0050896;response to hormone#GO:0009725;reproduction#GO:0000003;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011533.1|UniProtKB=W5N0L4 W5N0L4 PTHR12604:SF2 KU AUTOANTIGEN DNA HELICASE X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013737.1|UniProtKB=W5N8H9 W5N8H9 PTHR12137:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 13 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011018.1|UniProtKB=W5MYR1 W5MYR1 PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009305.1|UniProtKB=W5MSJ5 W5MSJ5 PTHR48493:SF1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 LEPOC|Ensembl=ENSLOCG00000013937.1|UniProtKB=W5N970 W5N970 PTHR36688:SF1 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010151.1|UniProtKB=W5MVL9 W5MVL9 PTHR24406:SF4 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN 692 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002960.1|UniProtKB=W5M530 W5M530 PTHR24051:SF5 SUSHI DOMAIN-CONTAINING PROTEIN 1 SUSHI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000000511.1|UniProtKB=W5LWQ6 W5LWQ6 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000001284.1|UniProtKB=W5LZC4 W5LZC4 PTHR11492:SF2 NUCLEAR FACTOR I NUCLEAR FACTOR 1 C-TYPE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010235.1|UniProtKB=W5MVX6 W5MVX6 PTHR11904:SF24 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013062.1|UniProtKB=W5N630 W5N630 PTHR31034:SF2 TRANSMEMBRANE PROTEIN 101 TRANSMEMBRANE PROTEIN 101 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000015684.1|UniProtKB=W5NF99 W5NF99 PTHR10071:SF106 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANS-ACTING T-CELL-SPECIFIC TRANSCRIPTION FACTOR GATA-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;immune system development#GO:0002520;negative regulation of metabolic process#GO:0009892;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;embryonic organ development#GO:0048568;embryo development#GO:0009790;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;regulation of epithelial cell differentiation#GO:0030856;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002862.1|UniProtKB=W5M4Q9 W5M4Q9 PTHR19300:SF9 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 4 galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002992.1|UniProtKB=W5M5B6 W5M5B6 DPP10 PTHR11731:SF21 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10 catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;transporter regulator activity#GO:0141108;peptidase activity#GO:0008233;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;regulation of metal ion transport#GO:0010959;organonitrogen compound metabolic process#GO:1901564;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of potassium ion transport#GO:0043266;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008680.1|UniProtKB=W5MQC8 W5MQC8 PTHR11733:SF127 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED EEF1AKMT4-ECE2 READTHROUGH TRANSCRIPT PROTEIN-RELATED hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 LEPOC|Ensembl=ENSLOCG00000005349.1|UniProtKB=W5MDI6 W5MDI6 PTHR24291:SF119 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 27C1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;cholesterol metabolic process#GO:0008203;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007024.1|UniProtKB=W5MJG7 W5MJG7 PTHR43674:SF2 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 hydrolase#PC00121 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 LEPOC|Ensembl=ENSLOCG00000005498.1|UniProtKB=W5ME26 W5ME26 PTHR21731:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 LEPOC|Ensembl=ENSLOCG00000004589.1|UniProtKB=W5MAT7 W5MAT7 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012412.1|UniProtKB=W5N3S9 W5N3S9 PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein modification process#GO:0036211;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015461.1|UniProtKB=W5NEH5 W5NEH5 PTHR22625:SF9 PLEXIN PLEXIN-B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;regulation of GTPase activity#GO:0043087;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of nervous system development#GO:0051962;positive regulation of developmental process#GO:0051094;regulation of neuron projection development#GO:0010975;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of multicellular organismal process#GO:0051240 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004619.1|UniProtKB=W5MAY1 W5MAY1 PTHR23316:SF11 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-8 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008838.1|UniProtKB=W5MQW5 W5MQW5 PTHR12582:SF6 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000002713.1|UniProtKB=W5M484 W5M484 PTHR14429:SF20 FIBROSIN FAMILY MEMBER FIBROSIN-1-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000002260.1|UniProtKB=W5M2U2 W5M2U2 PTHR13167:SF24 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 2 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013832.1|UniProtKB=W5N8V4 W5N8V4 PTHR11447:SF6 CELLULAR TUMOR ANTIGEN P53 CELLULAR TUMOR ANTIGEN P53 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 p53 pathway feedback loops 2#P04398>p53#P04668;p53 pathway by glucose deprivation#P04397>p53#P04640;p53 pathway#P00059>p53#P01485;Apoptosis signaling pathway#P00006>p53#P00273;P53 pathway feedback loops 1#P04392>p53#P04539;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#G04702;Wnt signaling pathway#P00057>p53#P01430 LEPOC|Ensembl=ENSLOCG00000004754.1|UniProtKB=W5MBE4 W5MBE4 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007815.1|UniProtKB=W5MM76 W5MM76 PTHR11309:SF149 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016197.1|UniProtKB=W5NH57 W5NH57 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000013320.1|UniProtKB=W5N713 W5N713 PTHR15583:SF14 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR D signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009991.1|UniProtKB=W5MV09 W5MV09 PTHR18821:SF8 PROKINETICIN PROKINETICIN-2 endothelial cell proliferation#GO:0001935;cellular process#GO:0009987;cell population proliferation#GO:0008283;epithelial cell proliferation#GO:0050673 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000008169.1|UniProtKB=W5MNH0 W5MNH0 PTHR14224:SF27 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006589.1|UniProtKB=W5MHV1 W5MHV1 PTHR23077:SF69 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;proteasomal protein catabolic process#GO:0010498;autophagosome maturation#GO:0097352;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;microtubule-based process#GO:0007017;response to chemical#GO:0042221;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017153.1|UniProtKB=W5NKN8 W5NKN8 PTHR12902:SF8 WASP-1 ACTIN-BINDING PROTEIN WASF1 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 cell leading edge#GO:0031252;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007302.1|UniProtKB=W5MKE1 W5MKE1 PTHR14093:SF19 HLA CLASS II GAMMA CHAIN THYROGLOBULIN cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;metabolic process#GO:0008152;hormone metabolic process#GO:0042445;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007988.1|UniProtKB=W5MMU3 W5MMU3 PTHR15136:SF9 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 1 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;ion binding#GO:0043167 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of metal ion transport#GO:0010959;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;regulation of calcium ion transport#GO:0051924;positive regulation of transport#GO:0051050;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010548.1|UniProtKB=W5MX19 W5MX19 PTHR24056:SF154 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 14 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001793.1|UniProtKB=W5M129 W5M129 PTHR18884:SF64 SEPTIN SEPTIN-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cell division#GO:0051301;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;biological regulation#GO:0065007;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910;regulation of exocytosis#GO:0017157 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell division site#GO:0032153;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015440.1|UniProtKB=W5NEE5 W5NEE5 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;establishment of organelle localization#GO:0051656;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;preribosome#GO:0030684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008381.1|UniProtKB=W5MP76 W5MP76 PTHR47221:SF6 FIBRINOGEN ALPHA CHAIN FIBRINOGEN ALPHA CHAIN LEPOC|Ensembl=ENSLOCG00000003407.1|UniProtKB=W5M6P5 W5M6P5 PTHR23257:SF775 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;calcium-mediated signaling#GO:0019722;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005594.1|UniProtKB=W5MEE4 W5MEE4 PTHR19143:SF185 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 5 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014315.1|UniProtKB=W5NAH0 W5NAH0 PTHR11878:SF8 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 2 calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;axon#GO:0030424;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006703.1|UniProtKB=W5MI86 W5MI86 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010905.1|UniProtKB=W5MYB1 W5MYB1 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000007041.1|UniProtKB=W5MJG3 W5MJG3 PTHR48081:SF33 AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C KYNURENINE FORMAMIDASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004218.1|UniProtKB=W5M9I6 W5M9I6 PTHR22738:SF4 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 4 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011723.1|UniProtKB=W5N1B0 W5N1B0 PTHR24361:SF656 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ERK#P00907;B cell activation#P00010>MEKK#P00369;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 LEPOC|Ensembl=ENSLOCG00000009855.1|UniProtKB=W5MUI7 W5MUI7 PTHR15082:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003374.1|UniProtKB=W5M6I9 W5M6I9 PTHR45685:SF1 HELICASE SRCAP-RELATED HELICASE SRCAP pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000011773.1|UniProtKB=W5N1G9 W5N1G9 PTHR12504:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002143.1|UniProtKB=W5M286 W5M286 SHCBP1L PTHR14695:SF7 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED TESTICULAR SPINDLE-ASSOCIATED PROTEIN SHCBP1L male gamete generation#GO:0048232;cell division#GO:0051301;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;cytoskeleton-dependent cytokinesis#GO:0061640;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;male meiotic nuclear division#GO:0007140;cytokinesis#GO:0000910;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010569.1|UniProtKB=W5MX46 W5MX46 VIM PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;neuron projection#GO:0043005;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000009647.1|UniProtKB=W5MTT2 W5MTT2 PTHR24384:SF192 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 47 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010682.1|UniProtKB=W5MXH6 W5MXH6 PTHR20988:SF2 TRANSMEMBRANE PROTEIN 183A-RELATED TRANSMEMBRANE PROTEIN 183A-RELATED biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000000728.1|UniProtKB=W5LXE9 W5LXE9 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008819.1|UniProtKB=W5MQR8 W5MQR8 PTHR14224:SF9 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009505.1|UniProtKB=W5MTB5 W5MTB5 PTHR15735:SF14 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1-LIKE cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004610.1|UniProtKB=W5MAW5 W5MAW5 PTHR11242:SF2 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED ARYL-HYDROCARBON-INTERACTING PROTEIN-LIKE 1 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003713.1|UniProtKB=W5M7W9 W5M7W9 PTHR11818:SF119 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN D structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006673.1|UniProtKB=W5MI48 W5MI48 PTHR11009:SF4 DER1-LIKE PROTEIN, DERLIN DERLIN-3 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010191.1|UniProtKB=W5MVS0 W5MVS0 PTHR21014:SF5 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 2 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009670.1|UniProtKB=W5MTV4 W5MTV4 PTHR36688:SF1 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016787.1|UniProtKB=W5NJE5 W5NJE5 PTHR11675:SF8 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 14 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017399.1|UniProtKB=W5NLJ5 W5NLJ5 PTHR26451:SF1002 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 148-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013027.1|UniProtKB=W5N5Y8 W5N5Y8 PTHR46331:SF2 VALACYCLOVIR HYDROLASE VALACYCLOVIR HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011665.1|UniProtKB=W5N123 W5N123 PTHR11346:SF104 GALECTIN GALECTIN-2 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000015787.1|UniProtKB=W5NFN4 W5NFN4 PTHR10751:SF42 GUANYLATE BINDING PROTEIN ATLASTIN-2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010090.1|UniProtKB=W5MVD5 W5MVD5 PTHR31247:SF7 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of Wnt signaling pathway#GO:0030177;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013115.1|UniProtKB=W5N6B1 W5N6B1 PTHR24347:SF431 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II DELTA 1 CHAIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 LEPOC|Ensembl=ENSLOCG00000009688.1|UniProtKB=W5MTY3 W5MTY3 PTHR10745:SF0 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 GLYCINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010338.1|UniProtKB=W5MWA3 W5MWA3 PTHR14969:SF18 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE POLYISOPRENOID DIPHOSPHATE_PHOSPHATE PHOSPHOHYDROLASE PLPP6 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011581.1|UniProtKB=W5N0T2 W5N0T2 PPP3CB PTHR45673:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT BETA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;calcineurin-mediated signaling#GO:0097720;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 T cell activation#P00053>Calcineurin#P01315;Wnt signaling pathway#P00057>Calcineurin#P01446;B cell activation#P00010>Calcineurin#P00386 LEPOC|Ensembl=ENSLOCG00000013184.1|UniProtKB=W5N6I1 W5N6I1 GCNT2 PTHR19297:SF183 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER N-ACETYLLACTOSAMINIDE BETA-1,6-N-ACETYLGLUCOSAMINYL-TRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011504.1|UniProtKB=W5N0J2 W5N0J2 PTHR11528:SF122 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein stabilization#GO:0050821;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 somatodendritic compartment#GO:0036477;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell body#GO:0044297;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000013448.1|UniProtKB=W5N7H0 W5N7H0 PTHR45659:SF11 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007319.1|UniProtKB=W5MKF7 W5MKF7 PTHR46037:SF5 PROTEIN ENHANCER OF SEVENLESS 2B SRC-LIKE-ADAPTER growth factor receptor binding#GO:0070851;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004473.1|UniProtKB=W5MAD7 W5MAD7 PTHR46065:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002954.1|UniProtKB=W5M518 W5M518 GPR139 PTHR46272:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 139-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008339.1|UniProtKB=W5MP20 W5MP20 PTHR12890:SF0 DREV PROTEIN PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000013245.1|UniProtKB=W5N6R6 W5N6R6 PTHR45620:SF2 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 LEPOC|Ensembl=ENSLOCG00000006551.1|UniProtKB=W5MHQ6 W5MHQ6 PTHR24006:SF905 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008217.1|UniProtKB=W5MNL7 W5MNL7 PTHR15284:SF1 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000012502.1|UniProtKB=W5N429 W5N429 PTHR15126:SF4 SH3-BINDING SH3 DOMAIN-BINDING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000007483.1|UniProtKB=W5ML24 W5ML24 PTHR43143:SF1 METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011712.1|UniProtKB=W5N186 W5N186 PTHR46105:SF7 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000361.1|UniProtKB=W5LW89 W5LW89 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016818.1|UniProtKB=W5NJI2 W5NJI2 PTHR45854:SF4 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000015703.1|UniProtKB=W5NFC3 W5NFC3 PTHR15394:SF3 SERINE HYDROLASE RBBP9 SERINE HYDROLASE RBBP9 LEPOC|Ensembl=ENSLOCG00000001159.1|UniProtKB=W5LYW8 W5LYW8 PTHR16091:SF1 TTC17 PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN 17 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017614.1|UniProtKB=W5NM60 W5NM60 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR HYDROXYCARBOXYLIC ACID RECEPTOR 2-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010363.1|UniProtKB=W5MWE3 W5MWE3 PTHR46251:SF1 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3B LEPOC|Ensembl=ENSLOCG00000005626.1|UniProtKB=W5MEK1 W5MEK1 PTHR10623:SF20 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;non-membrane-bounded organelle assembly#GO:0140694;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000016886.1|UniProtKB=W5NJR8 W5NJR8 PTHR12369:SF15 CHONDROITIN SYNTHASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000005676.1|UniProtKB=W5MEP5 W5MEP5 PTHR31807:SF37 AUGMIN FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 8 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000007262.1|UniProtKB=W5MK81 W5MK81 PTHR24025:SF21 DESMOGLEIN FAMILY MEMBER FAT ATYPICAL CADHERIN 3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000005973.1|UniProtKB=W5MFS1 W5MFS1 PTHR24166:SF23 ROLLING PEBBLES, ISOFORM B PROTEIN TANC1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002370.1|UniProtKB=W5M328 W5M328 PTHR11267:SF104 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000014542.1|UniProtKB=W5NB90 W5NB90 PTHR14949:SF46 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 SCHWANN CELL-SPECIFIC EGF-LIKE REPEAT AUTOCRINE FACTOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;heart development#GO:0007507;signal transduction#GO:0007165;left/right pattern formation#GO:0060972;circulatory system development#GO:0072359;animal organ development#GO:0048513;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;system development#GO:0048731;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;blood vessel development#GO:0001568;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016433.1|UniProtKB=W5NI38 W5NI38 LAMP5 PTHR11506:SF35 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013796.1|UniProtKB=W5N8Q8 W5N8Q8 F8 PTHR24543:SF320 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR VIII oxidoreductase#PC00176 Blood coagulation#P00011>FVIIIa#P00446;Blood coagulation#P00011>FVIII#P00405 LEPOC|Ensembl=ENSLOCG00000000796.1|UniProtKB=W5LXQ4 W5LXQ4 PTHR23236:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H POLYADENYLATE-BINDING PROTEIN 2 single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000011993.1|UniProtKB=W5N297 W5N297 PTHR24103:SF337 E3 UBIQUITIN-PROTEIN LIGASE TRIM ZINC-BINDING PROTEIN A33-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013607.1|UniProtKB=W5N831 W5N831 PTHR23239:SF347 INTERMEDIATE FILAMENT KERATIN 93-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006377.1|UniProtKB=W5MH48 W5MH48 PTHR11802:SF471 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002958.1|UniProtKB=W5M524 W5M524 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005718.1|UniProtKB=W5MEU4 W5MEU4 PTHR22847:SF731 WD40 REPEAT PROTEIN TNF RECEPTOR ASSOCIATED FACTOR 7 LEPOC|Ensembl=ENSLOCG00000015860.1|UniProtKB=W5NFW8 W5NFW8 PTHR23043:SF37 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NPAS4 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016858.1|UniProtKB=W5NJN3 W5NJN3 PTHR11616:SF316 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SOLUTE CARRIER FAMILY 6 MEMBER 1 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013826.1|UniProtKB=W5N8T7 W5N8T7 PTHR24365:SF524 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;activation of immune response#GO:0002253;pattern recognition receptor signaling pathway#GO:0002221;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;innate immune response-activating signaling pathway#GO:0002758;response to stress#GO:0006950;activation of innate immune response#GO:0002218;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;immune response-activating signaling pathway#GO:0002757;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015284.1|UniProtKB=W5NDU5 W5NDU5 PTHR13450:SF4 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 LARGE RIBOSOMAL SUBUNIT PROTEIN ML42 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002278.1|UniProtKB=W5M2Q3 W5M2Q3 PTHR14856:SF11 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN PQ-LOOP REPEAT-CONTAINING PROTEIN 1 ISOFORM X1 endosomal transport#GO:0016197;cellular localization#GO:0051641;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000013306.1|UniProtKB=W5N6Z1 W5N6Z1 PTHR12552:SF13 OLIGOPHRENIN 1 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTING WITH PH DOMAIN AND LEUCINE ZIPPER 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000007862.1|UniProtKB=W5MMD5 W5MMD5 PTHR21255:SF20 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 3 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011084.1|UniProtKB=W5MZ01 W5MZ01 PTHR11304:SF18 EPHRIN EPHRIN-B2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;neuron differentiation#GO:0030182;vasculature development#GO:0001944;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Angiogenesis#P00005>Eph#P00239 LEPOC|Ensembl=ENSLOCG00000017017.1|UniProtKB=W5NK76 W5NK76 PTHR10188:SF35 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;aspartate family amino acid metabolic process#GO:0009066;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005760.1|UniProtKB=W5MF01 W5MF01 PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;transcription elongation by RNA polymerase II#GO:0006368;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000015973.1|UniProtKB=W5NGA6 W5NGA6 PTHR11309:SF35 FRIZZLED PROTEIN SMOOTHENED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;smoothened signaling pathway#GO:0007224;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;pattern specification process#GO:0007389;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 LEPOC|Ensembl=ENSLOCG00000007937.1|UniProtKB=W5MMN6 W5MMN6 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000001877.1|UniProtKB=W5M1D2 W5M1D2 PTHR24012:SF365 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002688.1|UniProtKB=W5M460 W5M460 EPHA5 PTHR46877:SF13 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 5 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004100.1|UniProtKB=W5M937 W5M937 PTHR15503:SF39 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006946.1|UniProtKB=W5MJ43 W5MJ43 PTHR11211:SF41 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS HOMEOBOX 7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000834.1|UniProtKB=W5LXS2 W5LXS2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009641.1|UniProtKB=W5MTS4 W5MTS4 PTHR24339:SF32 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014083.1|UniProtKB=W5N9R4 W5N9R4 PTHR12295:SF9 FURRY-RELATED PROTEIN FURRY HOMOLOG-LIKE cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002659.1|UniProtKB=W5M432 W5M432 PTHR24031:SF706 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX27-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000008203.1|UniProtKB=W5MNK1 W5MNK1 PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;ciliary membrane#GO:0060170;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000091.1|UniProtKB=W5LVE6 W5LVE6 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013187.1|UniProtKB=W5N6I5 W5N6I5 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000010584.1|UniProtKB=W5MX80 W5MX80 PTHR24038:SF8 STABILIN STABILIN-1 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007141.1|UniProtKB=W5MJT4 W5MJT4 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002835.1|UniProtKB=W5M4N6 W5M4N6 PTHR19300:SF42 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009075.1|UniProtKB=W5MRP6 W5MRP6 PTHR11987:SF48 ALPHA-2,8-SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-POLY-ALPHA-2,8-SIALYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007416.1|UniProtKB=W5MKU1 W5MKU1 PTHR23105:SF31 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000008961.1|UniProtKB=W5MRB8 W5MRB8 PTHR10027:SF35 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 2-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion-gated channel activity#GO:0022839;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010859.1|UniProtKB=W5MY48 W5MY48 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013657.1|UniProtKB=W5N887 W5N887 PTHR13140:SF341 MYOSIN UNCONVENTIONAL MYOSIN-IE microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 animal organ development#GO:0048513;transport#GO:0006810;endocytosis#GO:0006897;developmental process#GO:0032502;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;kidney development#GO:0001822;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000017548.1|UniProtKB=W5NLZ4 W5NLZ4 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000003805.1|UniProtKB=W5M867 W5M867 PTHR24027:SF81 CADHERIN-23 CADHERIN-4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000006886.1|UniProtKB=W5MIW6 W5MIW6 LEPROT PTHR12050:SF3 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR GENE-RELATED PROTEIN endosomal transport#GO:0016197;regulation of cell communication#GO:0010646;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;vacuolar transport#GO:0007034;transport#GO:0006810;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;endosome transport via multivesicular body sorting pathway#GO:0032509;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014225.1|UniProtKB=W5NA58 W5NA58 PTHR11769:SF23 HYALURONIDASE HYALURONIDASE-1 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001716.1|UniProtKB=W5M0X7 W5M0X7 PTHR46682:SF1 ADHESION G-PROTEIN COUPLED RECEPTOR V1 ADHESION G-PROTEIN COUPLED RECEPTOR V1 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003107.1|UniProtKB=W5M5Q3 W5M5Q3 PTHR12353:SF7 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of system process#GO:0044057 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017879.1|UniProtKB=W5NMX3 W5NMX3 PTHR11984:SF105 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000001759.1|UniProtKB=W5M0X9 W5M0X9 PTHR17616:SF6 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER WW DOMAIN-CONTAINING TRANSCRIPTION REGULATOR PROTEIN 1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;hippo signaling#GO:0035329;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008950.1|UniProtKB=W5MR96 W5MR96 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004917.1|UniProtKB=W5MC16 W5MC16 PTHR19327:SF0 GOLGIN GOLGIN SUBFAMILY A MEMBER 4 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011411.1|UniProtKB=W5N066 W5N066 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006028.1|UniProtKB=W5MFW9 W5MFW9 PTHR10271:SF29 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS-RELATED response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;defense response to symbiont#GO:0140546 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003515.1|UniProtKB=W5M701 W5M701 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR COMPLEX PROTEIN WDR24 regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of macroautophagy#GO:0016239;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of autophagy#GO:0010508;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002187.1|UniProtKB=W5M2D6 W5M2D6 PTHR13582:SF0 M-PHASE PHOSPHOPROTEIN 6 M-PHASE PHOSPHOPROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 LEPOC|Ensembl=ENSLOCG00000007181.1|UniProtKB=W5MJY9 W5MJY9 PTHR11422:SF0 T-CELL SURFACE GLYCOPROTEIN CD4 T-CELL SURFACE GLYCOPROTEIN CD4 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009160.1|UniProtKB=W5MS05 W5MS05 PTHR28453:SF1 PROTEIN SNORC PROTEIN SNORC LEPOC|Ensembl=ENSLOCG00000011273.1|UniProtKB=W5MZP4 W5MZP4 PTHR24369:SF204 ANTIGEN BSP, PUTATIVE-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001560.1|UniProtKB=W5M0A8 W5M0A8 PTHR16469:SF27 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED LEPOC|Ensembl=ENSLOCG00000012703.1|UniProtKB=W5N4R8 W5N4R8 PTHR16520:SF3 KINETOCHORE SCAFFOLD 1 KINETOCHORE SCAFFOLD 1 nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;establishment of chromosome localization#GO:0051303;cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059;protein localization#GO:0008104;localization#GO:0051179;protein localization to kinetochore#GO:0034501;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;attachment of spindle microtubules to kinetochore#GO:0008608;protein localization to organelle#GO:0033365;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;establishment of organelle localization#GO:0051656 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010444.1|UniProtKB=W5MWP5 W5MWP5 PTHR11359:SF1 AMP DEAMINASE AMP DEAMINASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014672.1|UniProtKB=W5NBQ1 W5NBQ1 PTHR47222:SF1 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 592 LEPOC|Ensembl=ENSLOCG00000008605.1|UniProtKB=W5MQ05 W5MQ05 PTHR14167:SF48 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 19 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013077.1|UniProtKB=W5N648 W5N648 PTHR24412:SF491 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002415.1|UniProtKB=W5M375 W5M375 PTHR28668:SF1 TRANSMEMBRANE PROTEIN 234 TRANSMEMBRANE PROTEIN 234 LEPOC|Ensembl=ENSLOCG00000009835.1|UniProtKB=W5MUH2 W5MUH2 PTHR13817:SF179 TITIN CONTACTIN-4-LIKE structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012600.1|UniProtKB=W5N4F4 W5N4F4 PTHR46880:SF6 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN U1-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013948.1|UniProtKB=W5N985 W5N985 PTHR24173:SF78 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008099.1|UniProtKB=W5MN77 W5MN77 PTHR11986:SF18 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;ion binding#GO:0043167;anion binding#GO:0043168 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000010309.1|UniProtKB=W5MW71 W5MW71 PTHR22999:SF23 PX SERINE/THREONINE KINASE PXK SORTING NEXIN-16 LEPOC|Ensembl=ENSLOCG00000015880.1|UniProtKB=W5NG04 W5NG04 PTHR24416:SF573 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE 7 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010745.1|UniProtKB=W5MXQ4 W5MXQ4 PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002966.1|UniProtKB=W5M546 W5M546 PTHR44227:SF3 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC4 LEPOC|Ensembl=ENSLOCG00000016103.1|UniProtKB=W5NGT4 W5NGT4 PTHR11339:SF408 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-5B external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002728.1|UniProtKB=W5M4A3 W5M4A3 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010852.1|UniProtKB=W5MY44 W5MY44 PTHR16198:SF2 FAMILY NOT NAMED INO80 COMPLEX SUBUNIT D LEPOC|Ensembl=ENSLOCG00000007635.1|UniProtKB=W5MLK4 W5MLK4 PTHR21463:SF0 ANGIOPOIETIN-LIKE PROTEIN 8 ANGIOPOIETIN-LIKE PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000001422.1|UniProtKB=W5LZR0 W5LZR0 PTHR14499:SF122 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD7 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;positive regulation of transporter activity#GO:0032411;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017318.1|UniProtKB=W5NLB4 W5NLB4 PTHR13935:SF133 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 1B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003480.1|UniProtKB=W5M6W6 W5M6W6 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 protein binding#GO:0005515;nucleic acid binding#GO:0003676;transcription factor binding#GO:0008134;binding#GO:0005488;organic cyclic compound binding#GO:0097159;TBP-class protein binding#GO:0017025;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000010425.1|UniProtKB=W5MWM0 W5MWM0 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000001694.1|UniProtKB=W5M0P7 W5M0P7 PTHR11188:SF176 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006359.1|UniProtKB=W5MH29 W5MH29 PTHR31671:SF0 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of biosynthetic process#GO:0009891;vacuole organization#GO:0007033;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;positive regulation of RNA metabolic process#GO:0051254;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014592.1|UniProtKB=W5NBE8 W5NBE8 PTHR22792:SF71 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 6 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000376.1|UniProtKB=W5LWA4 W5LWA4 PTHR46182:SF3 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319-LIKE PROTEIN cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell motility#GO:0048870;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008988.1|UniProtKB=W5MRF7 W5MRF7 PTHR11751:SF469 ALANINE AMINOTRANSFERASE ALANINE TRANSAMINASE transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002075.1|UniProtKB=W5M215 W5M215 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017497.1|UniProtKB=W5NLU3 W5NLU3 PTHR14315:SF21 SPOT14 FAMILY MEMBER MID1-INTERACTING PROTEIN 1-LIKE biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006118.1|UniProtKB=W5MG85 W5MG85 PTHR11232:SF70 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010456.1|UniProtKB=W5MWQ5 W5MWQ5 PTHR46981:SF1 BIS(5'-ADENOSYL)-TRIPHOSPHATASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme binding#GO:0019899;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;regulation of proteolysis involved in protein catabolic process#GO:1903050;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;apoptotic process#GO:0006915;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;nucleoside phosphate catabolic process#GO:1901292;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;regulation of cellular process#GO:0050794;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of proteolysis involved in protein catabolic process#GO:1903051;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;signal transduction by p53 class mediator#GO:0072331;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;negative regulation of proteasomal protein catabolic process#GO:1901799;organic cyclic compound metabolic process#GO:1901360;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000017163.1|UniProtKB=W5NKQ6 W5NKQ6 PTHR41142:SF1 SI:DKEY-16J16.4 SI:DKEY-16J16.4 LEPOC|Ensembl=ENSLOCG00000007504.1|UniProtKB=W5ML49 W5ML49 PTHR18860:SF28 14-3-3 PROTEIN 14-3-3 PROTEIN BETA_ALPHA localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;CCKR signaling map#P06959>14-3-3 beta/alpha#P07038 LEPOC|Ensembl=ENSLOCG00000012265.1|UniProtKB=W5N382 W5N382 PTHR17614:SF11 ZINC FINGER-CONTAINING G PATCH DOMAIN-CONTAINING PROTEIN 8 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004098.1|UniProtKB=W5M938 W5M938 PTHR19375:SF554 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 70 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 LEPOC|Ensembl=ENSLOCG00000017391.1|UniProtKB=W5NLI7 W5NLI7 PTHR24232:SF90 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bioactive lipid receptor activity#GO:0045125;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012952.1|UniProtKB=W5N5N9 W5N5N9 PTHR23064:SF29 TROPONIN PARVALBUMIN-LIKE EF-HAND-CONTAINING PROTEIN multicellular organismal process#GO:0032501;nervous system process#GO:0050877;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010540.1|UniProtKB=W5MX10 W5MX10 PTHR42902:SF2 MALATE SYNTHASE MALATE SYNTHASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003551.1|UniProtKB=W5M736 W5M736 PTHR24206:SF95 OS06G0237300 PROTEIN CYTOSKELETON-ASSOCIATED LIM DOMAIN PROTEIN-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006348.1|UniProtKB=W5MH05 W5MH05 PTHR45659:SF1 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-C6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012868.1|UniProtKB=W5N5D1 W5N5D1 PTHR46221:SF2 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009608.1|UniProtKB=W5MTN3 W5MTN3 PTHR45752:SF160 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014147.1|UniProtKB=W5N9W9 W5N9W9 PTHR45913:SF21 EPM2A-INTERACTING PROTEIN 1 DUF4371 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015237.1|UniProtKB=W5NDQ0 W5NDQ0 PTHR12587:SF16 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-1 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330;neuromuscular junction development#GO:0007528 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006009.1|UniProtKB=W5MFV0 W5MFV0 PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005880.1|UniProtKB=W5MFE6 W5MFE6 PTHR43353:SF5 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824;Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481 LEPOC|Ensembl=ENSLOCG00000010111.1|UniProtKB=W5MVG7 W5MVG7 PTHR13723:SF141 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005701.1|UniProtKB=W5MES6 W5MES6 PTHR23068:SF9 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;DNA methylation#GO:0006306;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;DNA modification#GO:0006304;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;DNA alkylation#GO:0006305;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000013804.1|UniProtKB=W5N8R2 W5N8R2 PTHR34491:SF164 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED HOLOCENTRIC CHROMOSOME BINDING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000005137.1|UniProtKB=W5MCS6 W5MCS6 PTHR46511:SF1 MORN REPEAT-CONTAINING PROTEIN 3 MORN REPEAT-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000000884.1|UniProtKB=W5LXX4 W5LXX4 PTHR46317:SF3 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN DEOXYRIBONUCLEASE TATDN3-RELATED metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011159.1|UniProtKB=W5MZA0 W5MZA0 PTHR23216:SF1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006021.1|UniProtKB=W5MFW2 W5MFW2 PTHR32422:SF0 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006370.1|UniProtKB=W5MH30 W5MH30 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER LEPOC|Ensembl=ENSLOCG00000005050.1|UniProtKB=W5MCG9 W5MCG9 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013154.1|UniProtKB=W5N6E7 W5N6E7 PTHR33560:SF2 PROTEIN FAM227B PROTEIN FAM227B LEPOC|Ensembl=ENSLOCG00000015492.1|UniProtKB=W5NEL1 W5NEL1 PTHR11371:SF28 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 1 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000017306.1|UniProtKB=W5NLA2 W5NLA2 PTHR11437:SF10 RIBONUCLEASE ANGIOGENIN-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015983.1|UniProtKB=W5NGB9 W5NGB9 PTHR43999:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 binding#GO:0005488;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011401.1|UniProtKB=W5N064 W5N064 DNAAF2 PTHR22997:SF3 PIH1 DOMAIN-CONTAINING PROTEIN 1 PROTEIN KINTOUN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011461.1|UniProtKB=W5N0E1 W5N0E1 PTHR12616:SF8 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010613.1|UniProtKB=W5MX87 W5MX87 LRRD1 PTHR48051:SF49 FAMILY NOT NAMED LEUCINE-RICH REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006411.1|UniProtKB=W5MH86 W5MH86 PTHR24248:SF148 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H3 RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016065.1|UniProtKB=W5NGN5 W5NGN5 PTHR10513:SF8 DEOXYNUCLEOSIDE KINASE DEOXYGUANOSINE KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000006149.1|UniProtKB=W5MGB9 W5MGB9 PTHR47130:SF1 SI:DKEY-19B23.11-RELATED ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007073.1|UniProtKB=W5MJL2 W5MJL2 PTHR10201:SF29 MATRIX METALLOPROTEINASE 72 KDA TYPE IV COLLAGENASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 tissue remodeling#GO:0048771;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to hypoxia#GO:0001666;extracellular structure organization#GO:0043062;response to stress#GO:0006950;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;response to oxygen levels#GO:0070482;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000003569.1|UniProtKB=W5M771 W5M771 PTHR46135:SF4 NME/NM23 FAMILY MEMBER 8 DYNEIN AXONEMAL ASSEMBLY FACTOR 8 LEPOC|Ensembl=ENSLOCG00000010305.1|UniProtKB=W5MW85 W5MW85 PTHR23113:SF199 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Ras Pathway#P04393>RalGDS#P04551 LEPOC|Ensembl=ENSLOCG00000005574.1|UniProtKB=W5MEC3 W5MEC3 PTHR45832:SF21 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000001174.1|UniProtKB=W5LYW2 W5LYW2 PTHR37996:SF1 B- AND T-LYMPHOCYTE ATTENUATOR B- AND T-LYMPHOCYTE ATTENUATOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004004.1|UniProtKB=W5M8S4 W5M8S4 PTHR31230:SF1 MYELOID-DERIVED GROWTH FACTOR MYDGF MYELOID-DERIVED GROWTH FACTOR extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000008548.1|UniProtKB=W5MPT9 W5MPT9 PTHR23167:SF52 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017171.1|UniProtKB=W5NKR5 W5NKR5 PTHR22960:SF0 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000008200.1|UniProtKB=W5MNJ7 W5MNJ7 PTHR22883:SF8 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC1 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009994.1|UniProtKB=W5MV11 W5MV11 PTHR11818:SF22 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN N structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005823.1|UniProtKB=W5MF91 W5MF91 PTHR24027:SF432 CADHERIN-23 EGF-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000005470.1|UniProtKB=W5MDY6 W5MDY6 PTHR46484:SF7 SI:CH211-171H4.5-RELATED MYELIN-ASSOCIATED GLYCOPROTEIN-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000002245.1|UniProtKB=W5M2M1 W5M2M1 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000009092.1|UniProtKB=W5MRS7 W5MRS7 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000018356.1|UniProtKB=W5NP98 W5NP98 PTHR24244:SF0 NEUROPEPTIDE S RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004397.1|UniProtKB=W5MA41 W5MA41 PTHR48051:SF3 FAMILY NOT NAMED LEUCINE RICH REPEAT CONTAINING 8 VRAC SUBUNIT A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002765.1|UniProtKB=W5M4E9 W5M4E9 PTHR11486:SF18 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 14 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of sodium ion transport#GO:0002028;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of metal ion transport#GO:0010959;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular developmental process#GO:0048869;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000014371.1|UniProtKB=W5NAN7 W5NAN7 PTHR15635:SF11 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000014772.1|UniProtKB=W5NC30 W5NC30 PTHR31770:SF2 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000017901.1|UniProtKB=W5NMZ5 W5NMZ5 PTHR24369:SF9 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;developmental process#GO:0032502;regulation of signaling#GO:0023051;synaptic membrane adhesion#GO:0099560;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell junction assembly#GO:0034329;postsynapse organization#GO:0099173;localization within membrane#GO:0051668;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012940.1|UniProtKB=W5N5N7 W5N5N7 PTHR14058:SF11 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 2 amyloid-beta binding#GO:0001540;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 LEPOC|Ensembl=ENSLOCG00000014749.1|UniProtKB=W5NC01 W5NC01 PTHR47981:SF6 RAB FAMILY SI:DKEY-13A21.4 lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014781.1|UniProtKB=W5NC46 W5NC46 PTHR24300:SF346 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C44 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017717.1|UniProtKB=W5NMG3 W5NMG3 GPR68 PTHR24234:SF5 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011670.1|UniProtKB=W5N133 W5N133 PTHR14130:SF12 3BP-1 RELATED RHOGAP BARGIN-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of organelle organization#GO:0033043;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of hydrolase activity#GO:0051336;regulation of actin filament-based process#GO:0032970 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002407.1|UniProtKB=W5M360 W5M360 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 31-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012205.1|UniProtKB=W5N307 W5N307 PTHR11818:SF107 BETA/GAMMA CRYSTALLIN CRYGMX PROTEIN structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004808.1|UniProtKB=W5MBL2 W5MBL2 TRANK1 PTHR21529:SF4 MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2 TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006757.1|UniProtKB=W5MIF4 W5MIF4 PTHR21727:SF0 PHOSPHORYLATED CTD INTERACTING FACTOR 1 MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000002678.1|UniProtKB=W5M438 W5M438 LSAMP PTHR42757:SF22 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008559.1|UniProtKB=W5MPU9 W5MPU9 PTHR13135:SF0 CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26 PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006669.1|UniProtKB=W5MI46 W5MI46 FRZB PTHR11309:SF97 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>FrzB#P01461 LEPOC|Ensembl=ENSLOCG00000001822.1|UniProtKB=W5M147 W5M147 SERP1 PTHR15601:SF14 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 1 response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016639.1|UniProtKB=W5NIU6 W5NIU6 PTHR11081:SF8 FLAP ENDONUCLEASE FAMILY MEMBER EXONUCLEASE 1 DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000010895.1|UniProtKB=W5MY99 W5MY99 EEF1AKMT1 PTHR13200:SF0 EEF1A LYSINE METHYLTRANSFERASE 1 EEF1A LYSINE METHYLTRANSFERASE 1 LEPOC|Ensembl=ENSLOCG00000014460.1|UniProtKB=W5NAZ0 W5NAZ0 PTHR12226:SF2 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000012051.1|UniProtKB=W5N2H1 W5N2H1 PTHR13856:SF32 VHS DOMAIN CONTAINING PROTEIN FAMILY TARGET OF MYB1 MEMBRANE TRAFFICKING PROTEIN protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017793.1|UniProtKB=W5NMN8 W5NMN8 RAI2 PTHR23186:SF3 RETINOIC ACID-INDUCED PROTEIN 2 RETINOIC ACID-INDUCED PROTEIN 2 anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015566.1|UniProtKB=W5NEV6 W5NEV6 PTHR46698:SF2 CROSSVEINLESS 2 KIELIN_CHORDIN-LIKE PROTEIN regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014088.1|UniProtKB=W5N9Q0 W5N9Q0 SELENOS PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S cellular localization#GO:0051641;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000014020.1|UniProtKB=W5N9H7 W5N9H7 PTHR43884:SF9 ACYL-COA DEHYDROGENASE COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013919.1|UniProtKB=W5N960 W5N960 PTHR10807:SF35 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 7 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000002811.1|UniProtKB=W5M4K6 W5M4K6 PTHR11732:SF527 ALDO/KETO REDUCTASE ALDOSE REDUCTASE-RELATED PROTEIN 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007671.1|UniProtKB=W5MLQ8 W5MLQ8 PTHR10915:SF3 SYNDECAN SYNDECAN-4 cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009499.1|UniProtKB=W5MT98 W5MT98 TESK1 PTHR46485:SF3 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;positive regulation of actin filament bundle assembly#GO:0032233;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;actin cytoskeleton organization#GO:0030036;regulation of actin filament bundle assembly#GO:0032231;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008813.1|UniProtKB=W5MQR5 W5MQR5 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000000905.1|UniProtKB=W5LY07 W5LY07 PTHR17608:SF4 GENETIC SUPPRESSOR ELEMENT 1 GENETIC SUPPRESSOR ELEMENT 1 LEPOC|Ensembl=ENSLOCG00000002785.1|UniProtKB=W5M4G5 W5M4G5 SRRM1 PTHR23148:SF0 SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011441.1|UniProtKB=W5N0A2 W5N0A2 PTHR23222:SF0 PROHIBITIN PROHIBITIN 1 LEPOC|Ensembl=ENSLOCG00000017201.1|UniProtKB=W5NKV5 W5NKV5 PTHR11848:SF160 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 7 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000002825.1|UniProtKB=W5M4L9 W5M4L9 PTHR47977:SF10 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-36 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005791.1|UniProtKB=W5MF36 W5MF36 PTHR31838:SF1 CENTROSOMAL PROTEIN OF 55 KDA CENTROSOMAL PROTEIN OF 55 KDA LEPOC|Ensembl=ENSLOCG00000003750.1|UniProtKB=W5M7W2 W5M7W2 PTHR10828:SF17 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle#GO:0045787;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007566.1|UniProtKB=W5MLC5 W5MLC5 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005924.1|UniProtKB=W5MFJ3 W5MFJ3 ANKRD42 PTHR24201:SF2 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 42 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000007593.1|UniProtKB=W5MLF3 W5MLF3 PTHR17920:SF3 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000013182.1|UniProtKB=W5N6H7 W5N6H7 PTHR14484:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 LEPOC|Ensembl=ENSLOCG00000015671.1|UniProtKB=W5NF83 W5NF83 PTHR31735:SF3 VACUOLAR MEMBRANE PROTEIN YPL162C TRANSMEMBRANE PROTEIN 110-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004196.1|UniProtKB=W5M9F2 W5M9F2 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000016448.1|UniProtKB=W5NI55 W5NI55 PTHR14269:SF60 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CARDIOLIPIN SYNTHASE (CMP-FORMING) transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cardiolipin biosynthetic process#GO:0032049;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009102.1|UniProtKB=W5MRT5 W5MRT5 PTHR11771:SF161 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15B oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014193.1|UniProtKB=W5NA27 W5NA27 PTHR15321:SF3 TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 TP53-BINDING PROTEIN 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cell cycle process#GO:0010948;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;positive regulation of biosynthetic process#GO:0009891;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;signal transduction in response to DNA damage#GO:0042770;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;positive regulation of RNA metabolic process#GO:0051254;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010739.1|UniProtKB=W5MXR5 W5MXR5 PTHR21646:SF45 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004686.1|UniProtKB=W5MB51 W5MB51 PTHR24051:SF6 SUSHI DOMAIN-CONTAINING PROTEIN 1 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN-RELATED extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000000268.1|UniProtKB=W5LVY9 W5LVY9 PTHR19282:SF477 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008234.1|UniProtKB=W5MNN7 W5MNN7 PTHR11738:SF186 MHC CLASS I NK CELL RECEPTOR OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR immune response-regulating signaling pathway#GO:0002764;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011695.1|UniProtKB=W5N163 W5N163 PTHR13020:SF32 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6B PROTEIN negative regulation of gene expression#GO:0010629;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005635.1|UniProtKB=W5MEJ6 W5MEJ6 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009032.1|UniProtKB=W5MRJ9 W5MRJ9 PTHR46803:SF2 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;protein-folding chaperone binding#GO:0051087;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>CHIP#P01214 LEPOC|Ensembl=ENSLOCG00000004869.1|UniProtKB=W5MBV5 W5MBV5 PTHR28592:SF3 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000487.1|UniProtKB=W5LWM6 W5LWM6 PTHR45134:SF5 OS08G0543275 PROTEIN OS08G0543275 PROTEIN LEPOC|Ensembl=ENSLOCG00000002279.1|UniProtKB=W5M2R2 W5M2R2 PTHR12245:SF5 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013048.1|UniProtKB=W5N614 W5N614 IFT122 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;cell projection assembly#GO:0030031;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;non-motile cilium#GO:0097730;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000009046.1|UniProtKB=W5MRM1 W5MRM1 IWS1 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000770.1|UniProtKB=W5LXK5 W5LXK5 PTHR47960:SF8 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 RNA HELICASE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;non-membrane-bounded organelle assembly#GO:0140694;P-body assembly#GO:0033962;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000008863.1|UniProtKB=W5MQX9 W5MQX9 PTHR46144:SF2 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER MATRIN-TYPE PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000014776.1|UniProtKB=W5NC37 W5NC37 PTHR15818:SF2 G PATCH AND KOW-CONTAINING G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001835.1|UniProtKB=W5M191 W5M191 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000013814.1|UniProtKB=W5N8S5 W5N8S5 EIF5AL1 PTHR11673:SF6 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-RELATED nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008709.1|UniProtKB=W5MQE5 W5MQE5 PTHR10555:SF31 SORTING NEXIN SORTING NEXIN-2 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010439.1|UniProtKB=W5MWP3 W5MWP3 NEK9 PTHR44535:SF1 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK9 LEPOC|Ensembl=ENSLOCG00000013652.1|UniProtKB=W5N874 W5N874 PTHR12649:SF29 PEPTIDYL-TRNA HYDROLASE 2 AMINOACYL-TRNA HYDROLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015965.1|UniProtKB=W5NGA1 W5NGA1 PTHR46428:SF1 KELCH DOMAIN-CONTAINING PROTEIN 10 KELCH DOMAIN-CONTAINING PROTEIN 10 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of response to stress#GO:0080134;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000009659.1|UniProtKB=W5MTU3 W5MTU3 PTHR24412:SF22 KELCH PROTEIN KELCH-LIKE PROTEIN 40 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005083.1|UniProtKB=W5MCL3 W5MCL3 PTHR10985:SF15 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000013049.1|UniProtKB=W5N617 W5N617 PTHR46091:SF2 BLR7054 PROTEIN AMINE OXIDASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007832.1|UniProtKB=W5MM99 W5MM99 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016039.1|UniProtKB=W5NGK1 W5NGK1 PTHR15859:SF2 SETA BINDING PROTEIN 1 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010362.1|UniProtKB=W5MWF0 W5MWF0 PTHR16560:SF2 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN regulation of biological process#GO:0050789;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of receptor-mediated endocytosis#GO:0048259 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002784.1|UniProtKB=W5M4G7 W5M4G7 PTHR13994:SF46 NUDIX HYDROLASE RELATED NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 6 pyrophosphatase activity#GO:0016462;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001392.1|UniProtKB=W5LZM8 W5LZM8 PTHR24253:SF89 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 2 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004847.1|UniProtKB=W5MBT1 W5MBT1 PTHR13817:SF75 TITIN PROTEIN TURTLE HOMOLOG B-LIKE structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007936.1|UniProtKB=W5MMP7 W5MMP7 ADTRP PTHR10989:SF19 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-DEPENDENT TFPI-REGULATING PROTEIN-LIKE cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000008443.1|UniProtKB=W5MPF5 W5MPF5 PTHR14619:SF9 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000015746.1|UniProtKB=W5NFI2 W5NFI2 PTHR10398:SF2 AFADIN AFADIN non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>Afadin#P00146 LEPOC|Ensembl=ENSLOCG00000016865.1|UniProtKB=W5NJN9 W5NJN9 PTHR12049:SF7 PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 LEPOC|Ensembl=ENSLOCG00000011835.1|UniProtKB=W5N1P6 W5N1P6 PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055 LEPOC|Ensembl=ENSLOCG00000010299.1|UniProtKB=W5MW62 W5MW62 PTHR10909:SF390 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 3 nucleotide binding#GO:0000166;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007846.1|UniProtKB=W5MMB7 W5MMB7 PTHR11256:SF46 BCL-2 RELATED INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 protein binding#GO:0005515;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;binding#GO:0005488 mitochondrial fusion#GO:0008053;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;organelle fusion#GO:0048284;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Mcl1#P00308;CCKR signaling map#P06959>MCL1#G07275;CCKR signaling map#P06959>MCL1#G06982 LEPOC|Ensembl=ENSLOCG00000014793.1|UniProtKB=W5NC56 W5NC56 PTHR24329:SF340 HOMEOBOX PROTEIN ARISTALESS ARISTALESS RELATED HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000016424.1|UniProtKB=W5NI26 W5NI26 PTHR19328:SF54 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 2 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005006.1|UniProtKB=W5MCB7 W5MCB7 PTHR32074:SF2 RNA DEMETHYLASE ALKBH5 RNA DEMETHYLASE ALKBH5 catalytic activity, acting on RNA#GO:0140098;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;catalytic activity, acting on a nucleic acid#GO:0140640;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;organic substance transport#GO:0071702;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;mRNA processing#GO:0006397;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011902.1|UniProtKB=W5N1X7 W5N1X7 PTHR47222:SF3 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 532 LEPOC|Ensembl=ENSLOCG00000012280.1|UniProtKB=W5N398 W5N398 PTHR20875:SF8 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-LIKE calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000004603.1|UniProtKB=W5MAW0 W5MAW0 PTHR11977:SF27 VILLIN SCINDERIN LIKE A-RELATED cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;cellular component biogenesis#GO:0044085;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;cell projection organization#GO:0030030;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;central nervous system development#GO:0007417;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;cell projection assembly#GO:0030031;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000005922.1|UniProtKB=W5MFJ6 W5MFJ6 PTHR12646:SF0 NOT56 - RELATED DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009406.1|UniProtKB=W5MSY3 W5MSY3 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006708.1|UniProtKB=W5MI89 W5MI89 PTHR11537:SF87 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;presynaptic membrane#GO:0042734;cell leading edge#GO:0031252;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;distal axon#GO:0150034;postsynapse#GO:0098794;cell projection#GO:0042995;membrane protein complex#GO:0098796;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell projection membrane#GO:0031253;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016230.1|UniProtKB=W5NHA3 W5NHA3 PTHR10126:SF69 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 LEPOC|Ensembl=ENSLOCG00000010520.1|UniProtKB=W5MWZ1 W5MWZ1 ARHGAP26 PTHR12552:SF4 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 26 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>GRAF#P00926;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000014089.1|UniProtKB=W5N9Q5 W5N9Q5 PTHR11771:SF4 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX12 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 LEPOC|Ensembl=ENSLOCG00000012710.1|UniProtKB=W5N4T3 W5N4T3 PTHR24006:SF653 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013241.1|UniProtKB=W5N6Q8 W5N6Q8 PTHR23003:SF15 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN MYELIN EXPRESSION FACTOR 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001788.1|UniProtKB=W5M117 W5M117 PTHR12411:SF966 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L1-LIKE-RELATED cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003786.1|UniProtKB=W5M804 W5M804 PTHR12468:SF2 GPI MANNOSYLTRANSFERASE 2 GPI MANNOSYLTRANSFERASE 2 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007126.1|UniProtKB=W5MJR9 W5MJR9 PTHR12622:SF5 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009924.1|UniProtKB=W5MUT9 W5MUT9 PTHR10814:SF29 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 LEPOC|Ensembl=ENSLOCG00000014095.1|UniProtKB=W5N9Q4 W5N9Q4 PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;transcription elongation by RNA polymerase II#GO:0006368;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016677.1|UniProtKB=W5NIZ5 W5NIZ5 PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002568.1|UniProtKB=W5M3Q7 W5M3Q7 FOXL1 PTHR11829:SF204 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000012144.1|UniProtKB=W5N2T0 W5N2T0 PTHR11571:SF141 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011797.1|UniProtKB=W5N1J8 W5N1J8 PTHR15361:SF1 RAD51/NUKS-INTERACTING PROTEIN NUCLEAR UBIQUITOUS CASEIN AND CYCLIN-DEPENDENT KINASE SUBSTRATE 1 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013994.1|UniProtKB=W5N9E6 W5N9E6 PTHR14269:SF43 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000667.1|UniProtKB=W5LX83 W5LX83 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006168.1|UniProtKB=W5MGE8 W5MGE8 PTHR12106:SF27 SORTILIN RELATED SORTILIN-RELATED RECEPTOR membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001668.1|UniProtKB=W5M0R9 W5M0R9 COL6A6 PTHR24020:SF86 COLLAGEN ALPHA COLLAGEN, TYPE VI, ALPHA 4 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000005258.1|UniProtKB=W5MD89 W5MD89 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 mRNA splicing#P00058>U5#P01474 LEPOC|Ensembl=ENSLOCG00000009723.1|UniProtKB=W5MU15 W5MU15 PTHR16517:SF12 TUBBY-RELATED TUBBY-RELATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012796.1|UniProtKB=W5N564 W5N564 PTHR13140:SF356 MYOSIN UNCONVENTIONAL MYOSIN-VB microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000007636.1|UniProtKB=W5MLL5 W5MLL5 ATAD3A PTHR23075:SF0 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017633.1|UniProtKB=W5NM79 W5NM79 PTHR24343:SF166 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014945.1|UniProtKB=W5NCP5 W5NCP5 PTHR44186:SF1 FAMILY NOT NAMED BARDET-BIEDL SYNDROME 4 PROTEIN LEPOC|Ensembl=ENSLOCG00000015200.1|UniProtKB=W5NDJ8 W5NDJ8 PTHR23344:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOINOSITOL INOSITOLPHOSPHODIESTERASE GDPD2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010843.1|UniProtKB=W5MY30 W5MY30 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;U2-type spliceosomal complex#GO:0005684;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000011227.1|UniProtKB=W5MZI3 W5MZI3 PTHR31993:SF6 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000014704.1|UniProtKB=W5NBU1 W5NBU1 PTHR31893:SF2 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151B LEPOC|Ensembl=ENSLOCG00000004590.1|UniProtKB=W5MAT9 W5MAT9 SAMD8 PTHR21290:SF25 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015449.1|UniProtKB=W5NEF6 W5NEF6 PTHR12019:SF21 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN THYMOPOIETIN A peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000002178.1|UniProtKB=W5M2C9 W5M2C9 GPR149 PTHR24229:SF32 NEUROPEPTIDES RECEPTOR G-PROTEIN COUPLED RECEPTOR 149-RELATED neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004385.1|UniProtKB=W5MA31 W5MA31 PTHR13392:SF6 ATAXIN 1 ATAXIN-1-LIKE regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011293.1|UniProtKB=W5MZS0 W5MZS0 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016888.1|UniProtKB=W5NJS5 W5NJS5 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity#GO:0016874;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007134.1|UniProtKB=W5MJS9 W5MJS9 PTHR12674:SF2 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009043.1|UniProtKB=W5MRL2 W5MRL2 JMJD8 PTHR12480:SF21 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN 8 cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011769.1|UniProtKB=W5N1G4 W5N1G4 PTHR11346:SF26 GALECTIN GALECTIN-3 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;carbohydrate binding#GO:0030246;binding#GO:0005488;oligosaccharide binding#GO:0070492 negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of vesicle-mediated transport#GO:0060627;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;regulation of transport#GO:0051049;neutrophil chemotaxis#GO:0030593;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;myeloid leukocyte migration#GO:0097529;regulation of monoatomic ion transport#GO:0043269;negative regulation of cellular component organization#GO:0051129;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;macrophage chemotaxis#GO:0048246;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;neutrophil migration#GO:1990266;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of calcium ion transport#GO:0051924;positive regulation of transport#GO:0051050;negative regulation of transport#GO:0051051;cell motility#GO:0048870;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cell chemotaxis#GO:0060326;regulation of response to stimulus#GO:0048583;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;positive chemotaxis#GO:0050918;negative regulation of endocytosis#GO:0045806;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;external encapsulating structure#GO:0030312;membrane-bounded organelle#GO:0043227;collagen-containing extracellular matrix#GO:0062023;plasma membrane#GO:0005886 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006183.1|UniProtKB=W5MGG3 W5MGG3 PTHR10201:SF330 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-17 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005844.1|UniProtKB=W5MF95 W5MF95 ARSB PTHR10342:SF274 ARYLSULFATASE ARYLSULFATASE B LEPOC|Ensembl=ENSLOCG00000004176.1|UniProtKB=W5M9C9 W5M9C9 RASL11A PTHR45704:SF3 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11A LEPOC|Ensembl=ENSLOCG00000004967.1|UniProtKB=W5MC84 W5MC84 PTHR24404:SF36 ZINC FINGER PROTEIN DNA-BINDING PROTEIN IKAROS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007658.1|UniProtKB=W5MLN2 W5MLN2 PTHR28666:SF1 TRANSMEMBRANE PROTEIN 240 TRANSMEMBRANE PROTEIN 240 LEPOC|Ensembl=ENSLOCG00000013033.1|UniProtKB=W5N604 W5N604 PTHR10132:SF16 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER ALPHA-SARCOGLYCAN membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000006485.1|UniProtKB=W5MHI3 W5MHI3 PTHR45854:SF5 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1-LIKE nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000015401.1|UniProtKB=W5NE99 W5NE99 PTHR11388:SF89 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B3 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;bile acid transmembrane transporter activity#GO:0015125;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015924.1|UniProtKB=W5NG47 W5NG47 PTHR10655:SF17 LYSOPHOSPHOLIPASE-RELATED LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013186.1|UniProtKB=W5N6I4 W5N6I4 PTHR14499:SF10 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD6 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017123.1|UniProtKB=W5NKK5 W5NKK5 PTHR25465:SF5 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009610.1|UniProtKB=W5MTN5 W5MTN5 PTHR45620:SF24 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007882.1|UniProtKB=W5MMG2 W5MMG2 PTHR11863:SF225 STEROL DESATURASE METHYLSTEROL MONOOXYGENASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013685.1|UniProtKB=W5N8B2 W5N8B2 PTHR46491:SF3 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000014912.1|UniProtKB=W5NCK6 W5NCK6 PTHR43389:SF5 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009263.1|UniProtKB=W5MSE4 W5MSE4 PTHR13038:SF14 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9B cellular component assembly#GO:0022607;microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003672.1|UniProtKB=W5M7K3 W5M7K3 PTHR45982:SF1 REGULATOR OF CHROMOSOME CONDENSATION REGULATOR OF CHROMOSOME CONDENSATION LEPOC|Ensembl=ENSLOCG00000003445.1|UniProtKB=W5M6S6 W5M6S6 PTHR15427:SF27 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 5 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003069.1|UniProtKB=W5M5F2 W5M5F2 PTHR15215:SF2 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS2 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005419.1|UniProtKB=W5MDS8 W5MDS8 PTHR11818:SF7 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A2 structural molecule activity#GO:0005198 animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;nervous system process#GO:0050877;visual perception#GO:0007601;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;sensory perception#GO:0007600;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001241.1|UniProtKB=W5LZ60 W5LZ60 PTHR23167:SF87 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012078.1|UniProtKB=W5N2J8 W5N2J8 TMEM108 PTHR28673:SF1 TRANSMEMBRANE PROTEIN 108 TRANSMEMBRANE PROTEIN 108 cellular localization#GO:0051641;neurogenesis#GO:0022008;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;growth#GO:0040007;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;postsynapse organization#GO:0099173;cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell growth#GO:0016049;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;neuron projection development#GO:0031175;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;neuron projection morphogenesis#GO:0048812;establishment of localization in cell#GO:0051649;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;generation of neurons#GO:0048699 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;early endosome#GO:0005769;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000002722.1|UniProtKB=W5M499 W5M499 PTHR43544:SF7 SHORT-CHAIN DEHYDROGENASE/REDUCTASE NADB-LER2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003612.1|UniProtKB=W5M7C1 W5M7C1 PTHR37680:SF1 C130050O18RIK PROTEIN C130050O18RIK PROTEIN LEPOC|Ensembl=ENSLOCG00000013764.1|UniProtKB=W5N8M4 W5N8M4 PTHR46021:SF6 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 system development#GO:0048731;heart development#GO:0007507;circulatory system development#GO:0072359;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017203.1|UniProtKB=W5NKV7 W5NKV7 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203;protease#PC00190 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000003071.1|UniProtKB=W5M5F4 W5M5F4 PTHR45718:SF3 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002580.1|UniProtKB=W5M3S6 W5M3S6 PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;peroxisome organization#GO:0007031 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008337.1|UniProtKB=W5MP35 W5MP35 PTHR42874:SF1 URICASE URICASE LEPOC|Ensembl=ENSLOCG00000008586.1|UniProtKB=W5MPX8 W5MPX8 PTHR15871:SF1 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015779.1|UniProtKB=W5NFL7 W5NFL7 PTHR15715:SF26 CENTROSOMAL PROTEIN OF 170 KDA COILED-COIL DOMAIN-CONTAINING PROTEIN 136 male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;endomembrane system organization#GO:0010256;spermatid differentiation#GO:0048515;secretory granule organization#GO:0033363;cellular anatomical entity morphogenesis#GO:0032989;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;spermatogenesis#GO:0007283;reproductive process#GO:0022414;vesicle organization#GO:0016050;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;organelle assembly#GO:0070925;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;spermatid development#GO:0007286;reproduction#GO:0000003;organelle organization#GO:0006996;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501 bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010709.1|UniProtKB=W5MXK9 W5MXK9 PTHR12274:SF7 GRANULIN GRANULINS cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003040.1|UniProtKB=W5M5C5 W5M5C5 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000008370.1|UniProtKB=W5MP72 W5MP72 PTHR24353:SF116 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 LEPOC|Ensembl=ENSLOCG00000001185.1|UniProtKB=W5LYX8 W5LYX8 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006900.1|UniProtKB=W5MIY3 W5MIY3 PTHR45938:SF6 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 1 transforming growth factor beta binding#GO:0050431;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000000863.1|UniProtKB=W5LXV2 W5LXV2 TATDN3 PTHR46317:SF7 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN DEOXYRIBONUCLEASE TATDN3-RELATED metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010583.1|UniProtKB=W5MX56 W5MX56 PTHR24366:SF61 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 52 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005558.1|UniProtKB=W5ME97 W5ME97 PTHR14066:SF10 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;circulatory system process#GO:0003013;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cGMP biosynthetic process#GO:0006182;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;blood circulation#GO:0008015;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;neuropeptide signaling pathway#GO:0007218;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;regulation of systemic arterial blood pressure#GO:0003073;cellular biosynthetic process#GO:0044249;cGMP-mediated signaling#GO:0019934;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of blood pressure#GO:0008217;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935;purine ribonucleotide biosynthetic process#GO:0009152 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011295.1|UniProtKB=W5MZS3 W5MZS3 MZT1 PTHR28520:SF2 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;supramolecular fiber organization#GO:0097435;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;organelle organization#GO:0006996;protein polymerization#GO:0051258;cell cycle#GO:0007049;organelle fission#GO:0048285;microtubule nucleation#GO:0007020 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009958.1|UniProtKB=W5MUX1 W5MUX1 PTHR46012:SF1 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 2 UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000013818.1|UniProtKB=W5N8T4 W5N8T4 PTHR14167:SF56 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007976.1|UniProtKB=W5MMT2 W5MMT2 PTHR10015:SF213 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 4 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000014436.1|UniProtKB=W5NAW5 W5NAW5 PTHR11036:SF28 SEMAPHORIN SEMA DOMAIN, IMMUNOGLOBULIN DOMAIN (IG), SHORT BASIC DOMAIN, SECRETED, (SEMAPHORIN) 3GA ISOFORM X1-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cell communication#GO:0007154;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;stem cell development#GO:0048864;regulation of locomotion#GO:0040012;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;chemotaxis#GO:0006935;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;ameboidal-type cell migration#GO:0001667;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004354.1|UniProtKB=W5M9Z9 W5M9Z9 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000011429.1|UniProtKB=W5N090 W5N090 PTHR45662:SF8 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endoplasmic reticulum#GO:0005783 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011454.1|UniProtKB=W5N0E0 W5N0E0 NEMF PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000007374.1|UniProtKB=W5MKN2 W5MKN2 PTHR15505:SF1 RIIA DOMAIN-CONTAINING PROTEIN 1 BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 TGF-beta signaling pathway#P00052>BAMBI#P01287 LEPOC|Ensembl=ENSLOCG00000005056.1|UniProtKB=W5MCK0 W5MCK0 PTHR22115:SF1 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 50 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006164.1|UniProtKB=W5MGD7 W5MGD7 SCP2 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008880.1|UniProtKB=W5MQZ8 W5MQZ8 PTHR11781:SF20 IODOTHYRONINE DEIODINASE TYPE II IODOTHYRONINE DEIODINASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;metabolic process#GO:0008152;hormone metabolic process#GO:0042445;organic substance metabolic process#GO:0071704 metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014699.1|UniProtKB=W5NBT8 W5NBT8 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000932.1|UniProtKB=W5LY33 W5LY33 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013411.1|UniProtKB=W5N7C7 W5N7C7 NFE2L1 PTHR24411:SF31 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR ENDOPLASMIC RETICULUM MEMBRANE SENSOR NFE2L1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000001413.1|UniProtKB=W5LZQ3 W5LZQ3 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014882.1|UniProtKB=W5NCG7 W5NCG7 PTHR45799:SF7 RETICULON-LIKE PROTEIN RETICULON head development#GO:0060322;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;endoplasmic reticulum organization#GO:0007029;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;endomembrane system organization#GO:0010256;brain development#GO:0007420;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell junction#GO:0030054;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000000529.1|UniProtKB=W5LWW1 W5LWW1 PTHR11505:SF205 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000002829.1|UniProtKB=W5M4M0 W5M4M0 PTHR24329:SF322 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012554.1|UniProtKB=W5N4A2 W5N4A2 PTHR11937:SF514 ACTIN ACTIN-RELATED PROTEIN 3B-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006027.1|UniProtKB=W5MFX1 W5MFX1 PTHR11875:SF169 TESTIS-SPECIFIC Y-ENCODED PROTEIN SIMILAR TO SET BETA ISOFORM protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000236.1|UniProtKB=W5LVV6 W5LVV6 PTHR13962:SF17 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000012313.1|UniProtKB=W5N3D7 W5N3D7 CCDC57 PTHR46725:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;positive regulation of cell cycle#GO:0045787;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;microtubule polymerization#GO:0046785;supramolecular fiber organization#GO:0097435;positive regulation of mitotic cell cycle#GO:0045931;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;protein polymerization#GO:0051258;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;plasma membrane bounded cell projection assembly#GO:0120031;regulation of mitotic cell cycle#GO:0007346;microtubule nucleation#GO:0007020 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;centriolar satellite#GO:0034451;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000012805.1|UniProtKB=W5N549 W5N549 PTHR10722:SF0 60S RIBOSOMAL PROTEIN L19 RIBOSOMAL PROTEIN L19 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007742.1|UniProtKB=W5MLZ0 W5MLZ0 PTHR48051:SF15 FAMILY NOT NAMED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011316.1|UniProtKB=W5MZV0 W5MZV0 PTHR24028:SF264 CADHERIN-87A PROTOCADHERIN 1 GAMMA 32 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000012161.1|UniProtKB=W5N2U9 W5N2U9 PTHR23044:SF61 3'-5' EXONUCLEASE ERI1-RELATED 3'-5' EXORIBONUCLEASE 1-RELATED RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000015962.1|UniProtKB=W5NG94 W5NG94 PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000007920.1|UniProtKB=W5MML9 W5MML9 PTHR19876:SF20 COATOMER PRE-MRNA-SPLICING FACTOR PRP46-LIKE endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000006854.1|UniProtKB=W5MIS7 W5MIS7 PTHR14614:SF130 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011192.1|UniProtKB=W5MZD8 W5MZD8 PTHR22923:SF111 CEREBELLIN-RELATED C1Q AND TNF-RELATED 6A-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001953.1|UniProtKB=W5M1J6 W5M1J6 CHST8 PTHR12137:SF7 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 8 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007313.1|UniProtKB=W5MKG4 W5MKG4 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008131.1|UniProtKB=W5MNB0 W5MNB0 PTHR24346:SF35 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE NIM1-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005988.1|UniProtKB=W5MFT8 W5MFT8 TNKS2 PTHR24180:SF11 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;positive regulation of Wnt signaling pathway#GO:0030177;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of chromosome organization#GO:0033044;regulation of cell communication#GO:0010646;regulation of organelle organization#GO:0033043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000007744.1|UniProtKB=W5MM02 W5MM02 PTHR46051:SF2 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 2 inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SHIP#P00839;PI3 kinase pathway#P00048>SHIP#P01200;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>SHIP2#P00897 LEPOC|Ensembl=ENSLOCG00000003174.1|UniProtKB=W5M5V4 W5M5V4 PTHR11922:SF2 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>GMP synthase#P02899 LEPOC|Ensembl=ENSLOCG00000004266.1|UniProtKB=W5M9P0 W5M9P0 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000442.1|UniProtKB=W5LWH9 W5LWH9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003741.1|UniProtKB=W5M7U7 W5M7U7 PTHR12863:SF1 FATTY ACID HYDROXYLASE FATTY ACID 2-HYDROXYLASE hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000011211.1|UniProtKB=W5MZG9 W5MZG9 NFX1 PTHR12360:SF12 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011466.1|UniProtKB=W5N0C5 W5N0C5 PTHR19300:SF5 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 1 cytoskeletal protein binding#GO:0008092;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;protein binding#GO:0005515;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003279.1|UniProtKB=W5M661 W5M661 PTHR12585:SF71 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG-RELATED protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;sister chromatid cohesion#GO:0007062;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cohesin complex#GO:0008278;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017505.1|UniProtKB=W5NLV1 W5NLV1 PTHR10424:SF73 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP FC1 ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000011338.1|UniProtKB=W5MZW9 W5MZW9 PTHR11220:SF7 HEME-BINDING PROTEIN-RELATED SOUL PROTEIN tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 LEPOC|Ensembl=ENSLOCG00000006811.1|UniProtKB=W5MIM5 W5MIM5 PTHR15711:SF17 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005418.1|UniProtKB=W5MDS6 W5MDS6 PTHR34920:SF1 B-CELL LYMPHOMA/LEUKEMIA 10 B-CELL LYMPHOMA_LEUKEMIA 10 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;NF-kappaB binding#GO:0051059;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;transcription factor binding#GO:0008134;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;DNA-binding transcription factor binding#GO:0140297;kinase activator activity#GO:0019209;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein kinase binding#GO:0019901 positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013701.1|UniProtKB=W5N8E0 W5N8E0 KIF1C PTHR24115:SF322 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1C cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;transport along microtubule#GO:0010970;localization#GO:0051179;axo-dendritic transport#GO:0008088;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016721.1|UniProtKB=W5NJ49 W5NJ49 PTHR24044:SF423 NOTCH LIGAND FAMILY MEMBER PROTEIN DELTA HOMOLOG 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011994.1|UniProtKB=W5N292 W5N292 PTHR13809:SF25 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-2 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;CCKR signaling map#P06959>Gbeta/gamma#P07197;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Nicotine pharmacodynamics pathway#P06587>GNG#P06590;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Gonadotropin-releasing hormone receptor pathway#P06664>Ggamma#P06754;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 LEPOC|Ensembl=ENSLOCG00000011183.1|UniProtKB=W5MZC5 W5MZC5 PTHR12878:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014204.1|UniProtKB=W5NA36 W5NA36 PTHR24028:SF123 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 4 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000008155.1|UniProtKB=W5MNE2 W5MNE2 PTHR45845:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PLECKSTRIN HOMOLOGY AND RHOGEF DOMAIN CONTAINING G4B guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012062.1|UniProtKB=W5N2I1 W5N2I1 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001550.1|UniProtKB=W5M070 W5M070 PTHR12454:SF3 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE A ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011524.1|UniProtKB=W5N0N4 W5N0N4 PTHR45703:SF36 DYNEIN HEAVY CHAIN DYNEIN HEAVY CHAIN, CYTOPLASMIC microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002061.1|UniProtKB=W5M1Y0 W5M1Y0 PTHR21041:SF3 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN OSTEOCLAST STIMULATORY TRANSMEMBRANE PROTEIN LEPOC|Ensembl=ENSLOCG00000017347.1|UniProtKB=W5NLE3 W5NLE3 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011979.1|UniProtKB=W5N270 W5N270 PTHR11848:SF133 TGF-BETA FAMILY INHIBIN BETA A CHAIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba#P06723;TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700 LEPOC|Ensembl=ENSLOCG00000010987.1|UniProtKB=W5MYQ3 W5MYQ3 PTHR13886:SF2 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;signaling receptor complex adaptor activity#GO:0030159;kinase binding#GO:0019900 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000870.1|UniProtKB=W5LXW1 W5LXW1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013029.1|UniProtKB=W5N5Y7 W5N5Y7 OXLD1 PTHR21193:SF3 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014868.1|UniProtKB=W5NCF2 W5NCF2 PTHR21366:SF14 GLYOXALASE FAMILY PROTEIN GLYOXALASE DOMAIN-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000009582.1|UniProtKB=W5MTJ6 W5MTJ6 PTHR47301:SF1 HYPOTHETICAL PROTEIN LOC681006 CHROMOSOME 10 OPEN READING FRAME 82 LEPOC|Ensembl=ENSLOCG00000002849.1|UniProtKB=W5M4P9 W5M4P9 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED LEPOC|Ensembl=ENSLOCG00000002052.1|UniProtKB=W5M1X8 W5M1X8 PTHR12183:SF4 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007021.1|UniProtKB=W5MJE2 W5MJE2 PTHR10809:SF12 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B_C protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000018290.1|UniProtKB=W5NP32 W5NP32 PTHR22750:SF10 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017125.1|UniProtKB=W5NKK2 W5NKK2 ZUP1 PTHR24403:SF82 ZINC FINGER PROTEIN ZINC FINGER-CONTAINING UBIQUITIN PEPTIDASE 1 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001047.1|UniProtKB=W5LYH2 W5LYH2 PTHR10655:SF13 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011218.1|UniProtKB=W5MZH0 W5MZH0 PTHR12080:SF125 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN-LIKE immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007405.1|UniProtKB=W5MKS6 W5MKS6 PTHR23049:SF9 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR_CARDIAC MUSCLE ISOFORM cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 blood circulation#GO:0008015;cellular developmental process#GO:0048869;heart development#GO:0007507;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;animal organ development#GO:0048513;system process#GO:0003008;developmental process#GO:0032502;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle contraction#GO:0060048;cell fate commitment#GO:0045165;cellular process#GO:0009987;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;cell fate specification#GO:0001708;cell differentiation#GO:0030154;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;myosin complex#GO:0016459;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006801.1|UniProtKB=W5MIL8 W5MIL8 PTHR45630:SF7 CATION-TRANSPORTING ATPASE-RELATED ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;P-type ion transporter activity#GO:0015662;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;intracellular monoatomic ion homeostasis#GO:0006873 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010873.1|UniProtKB=W5MY65 W5MY65 PTHR19433:SF133 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED IMMUNE-TYPE RECEPTOR 5 PRECURSOR-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005367.1|UniProtKB=W5MDL2 W5MDL2 PTHR24251:SF26 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;asymmetric synapse#GO:0032279 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003566.1|UniProtKB=W5M767 W5M767 PTHR21258:SF43 DOCKING PROTEIN RELATED DOCKING PROTEIN 6 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006836.1|UniProtKB=W5MIR2 W5MIR2 PTHR13036:SF0 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017745.1|UniProtKB=W5NMJ0 W5NMJ0 PTHR11462:SF8 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06891;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;PDGF signaling pathway#P00047>c-Jun#P01163;B cell activation#P00010>jun#P00401;FAS signaling pathway#P00020>c-Jun#P00601;CCKR signaling map#P06959>JUN#G06983;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06677;Toll receptor signaling pathway#P00054>AP1#P01355;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#P06710;Angiogenesis#P00005>c-Jun#P00220;Oxidative stress response#P00046>c-jun#P01132;CCKR signaling map#P06959>JUN#P07114;Ras Pathway#P04393>AP1#P04560;Apoptosis signaling pathway#P00006>c-Jun#P00303;Huntington disease#P00029>c-Jun#P00776;T cell activation#P00053>jun#P01335;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838;CCKR signaling map#P06959>JUN#G07276 LEPOC|Ensembl=ENSLOCG00000008114.1|UniProtKB=W5MNA3 W5MNA3 PTHR24372:SF68 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015884.1|UniProtKB=W5NG03 W5NG03 PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to cold#GO:0009409;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000016.1|UniProtKB=W5LV59 W5LV59 PTHR11266:SF28 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 SI:CH211-120K19.1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;non-membrane-bounded organelle assembly#GO:0140694 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000469.1|UniProtKB=W5LWK4 W5LWK4 PTHR19960:SF7 TEKTIN TEKTIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000004152.1|UniProtKB=W5M9A9 W5M9A9 PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE cation binding#GO:0043169;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;phosphoric ester hydrolase activity#GO:0042578 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 LEPOC|Ensembl=ENSLOCG00000018267.1|UniProtKB=W5NP09 W5NP09 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015111.1|UniProtKB=W5ND90 W5ND90 PTHR15073:SF5 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 3 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000009410.1|UniProtKB=W5MSX8 W5MSX8 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015363.1|UniProtKB=W5NE49 W5NE49 PTHR16001:SF7 ECTO-NOX DISULFIDE-THIOL EXCHANGER ECTO-NOX DISULFIDE-THIOL EXCHANGER 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011440.1|UniProtKB=W5N0A7 W5N0A7 PTHR13489:SF0 MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000009766.1|UniProtKB=W5MU75 W5MU75 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;transport#GO:0006810;homeostatic process#GO:0042592;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;inorganic anion transport#GO:0015698 brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002049.1|UniProtKB=W5M211 W5M211 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;proteasome binding#GO:0070628;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein-containing complex binding#GO:0044877;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of proteasomal protein catabolic process#GO:0061136;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005269.1|UniProtKB=W5MD88 W5MD88 PTHR24229:SF18 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B_W RECEPTOR TYPE 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012146.1|UniProtKB=W5N2U3 W5N2U3 PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mitochondrial gene expression#GO:0140053;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;tRNA 3'-end processing#GO:0042780;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005021.1|UniProtKB=W5MCD4 W5MCD4 PTHR39654:SF5 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75A-LIKE ISOFORM X1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75B LEPOC|Ensembl=ENSLOCG00000005392.1|UniProtKB=W5MDP1 W5MDP1 PTHR11348:SF18 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 1 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cell adhesion#GO:0007155;cell communication#GO:0007154;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;signaling#GO:0023052 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000006151.1|UniProtKB=W5MGC2 W5MGC2 PTHR15380:SF2 CEROID-LIPOFUSCINOSIS, NEURONAL 5 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 5 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;cellular process#GO:0009987;lytic vacuole organization#GO:0080171;organelle organization#GO:0006996 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000016349.1|UniProtKB=W5NHT0 W5NHT0 PTHR47027:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN RIBONUCLEASE H LEPOC|Ensembl=ENSLOCG00000012914.1|UniProtKB=W5N5J8 W5N5J8 PTHR12858:SF2 RIBOSOME BIOGENESIS PROTEIN RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG snoRNA binding#GO:0030515;GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000009929.1|UniProtKB=W5MUT2 W5MUT2 PTHR13598:SF5 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 2 envelope#GO:0031975;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013284.1|UniProtKB=W5N6V6 W5N6V6 PTHR11652:SF14 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008986.1|UniProtKB=W5MRH7 W5MRH7 PTHR24023:SF1120 COLLAGEN ALPHA COLLAGEN ALPHA-2(IV) CHAIN ISOFORM X1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000017320.1|UniProtKB=W5NLB6 W5NLB6 PTHR38004:SF1 PROLINE-RICH PROTEIN 33 PROLINE-RICH PROTEIN 33 LEPOC|Ensembl=ENSLOCG00000008903.1|UniProtKB=W5MR31 W5MR31 PTHR22811:SF40 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000003481.1|UniProtKB=W5M6W8 W5M6W8 PTHR28620:SF1 CENTROMERE PROTEIN V CENP-V_GFA DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011474.1|UniProtKB=W5N0E2 W5N0E2 MRPL58 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003641.1|UniProtKB=W5M7G9 W5M7G9 PTHR23085:SF6 GH28348P JUNCTOPHILIN-1 sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009531.1|UniProtKB=W5MTD8 W5MTD8 PTHR47333:SF4 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010004.1|UniProtKB=W5MV23 W5MV23 PTHR24070:SF264 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 p53 pathway by glucose deprivation#P04397>Rheb#P04642;CCKR signaling map#P06959>RHEB-GTP#P07224;CCKR signaling map#P06959>RHEB-GDP#P07175 LEPOC|Ensembl=ENSLOCG00000005342.1|UniProtKB=W5MDI1 W5MDI1 PTHR11819:SF171 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013522.1|UniProtKB=W5N7S1 W5N7S1 PTHR13866:SF25 SPARC OSTEONECTIN SPARC-LIKE 1 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000018289.1|UniProtKB=W5NP31 W5NP31 PTHR15405:SF7 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 2 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001417.1|UniProtKB=W5LZQ9 W5LZQ9 PTHR16112:SF18 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 5 protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000831.1|UniProtKB=W5LXR8 W5LXR8 PTHR10751:SF1 GUANYLATE BINDING PROTEIN RING FINGER PROTEIN 112 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000006897.1|UniProtKB=W5MIY5 W5MIY5 PTHR46465:SF2 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000012237.1|UniProtKB=W5N344 W5N344 PTHR20855:SF26 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010407.1|UniProtKB=W5MWJ9 W5MWJ9 SIKE1 PTHR12186:SF4 SIKE FAMILY MEMBER SUPPRESSOR OF IKBKE 1 LEPOC|Ensembl=ENSLOCG00000011374.1|UniProtKB=W5N018 W5N018 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011389.1|UniProtKB=W5N040 W5N040 PTHR14319:SF6 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 TRANSMEMBRANE PROTEIN 8B cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015331.1|UniProtKB=W5NE06 W5NE06 PTHR47012:SF3 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 LAMIN TAIL DOMAIN CONTAINING 1 cytoplasm#GO:0005737;envelope#GO:0031975;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000198.1|UniProtKB=W5LVR4 W5LVR4 PTHR15294:SF3 RETINOVIN-RELATED SUMO-SPECIFIC ISOPEPTIDASE USPL1 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;SUMO binding#GO:0032183 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nucleus organization#GO:0006997;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;protein modification by small protein removal#GO:0070646;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004710.1|UniProtKB=W5MB92 W5MB92 PTHR17204:SF25 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED RRM DOMAIN-CONTAINING PROTEIN RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016602.1|UniProtKB=W5NIP5 W5NIP5 PTHR24083:SF98 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018251.1|UniProtKB=W5NNZ3 W5NNZ3 PTHR19290:SF162 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010604.1|UniProtKB=W5MX76 W5MX76 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000016418.1|UniProtKB=W5NI20 W5NI20 PTHR23158:SF54 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009805.1|UniProtKB=W5MUC5 W5MUC5 PTHR12732:SF0 UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING PCI DOMAIN-CONTAINING PROTEIN 2 RNA binding#GO:0003723;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular localization#GO:0051641;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;organic substance transport#GO:0071702;organic cyclic compound metabolic process#GO:1901360;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;cellular nitrogen compound biosynthetic process#GO:0044271;transcription elongation by RNA polymerase II#GO:0006368;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;mRNA transport#GO:0051028;primary metabolic process#GO:0044238;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;heterocycle biosynthetic process#GO:0018130;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;organelle organization#GO:0006996;chromosome organization#GO:0051276;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;aromatic compound biosynthetic process#GO:0019438;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;transcription export complex 2#GO:0070390;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003265.1|UniProtKB=W5M645 W5M645 PTHR32289:SF2 PROTEIN FAM167A ALANINE AND ARGININE-RICH DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009569.1|UniProtKB=W5MTI7 W5MTI7 TSTD2 PTHR43268:SF6 THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009177.1|UniProtKB=W5MS36 W5MS36 PTHR19443:SF28 HEXOKINASE HEXOKINASE HKDC1 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;intracellular chemical homeostasis#GO:0055082;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;organophosphate catabolic process#GO:0046434;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate phosphorylation#GO:0046835;organonitrogen compound metabolic process#GO:1901564;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;intracellular glucose homeostasis#GO:0001678;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 LEPOC|Ensembl=ENSLOCG00000017718.1|UniProtKB=W5NMG4 W5NMG4 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 19 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>TCR Beta#P01299 LEPOC|Ensembl=ENSLOCG00000017679.1|UniProtKB=W5NMC5 W5NMC5 PTHR16433:SF0 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mannosyltransferase complex#GO:0031501;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005328.1|UniProtKB=W5MDF9 W5MDF9 PTHR15741:SF40 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MLX-INTERACTING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016995.1|UniProtKB=W5NK51 W5NK51 PTHR24056:SF570 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 19 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002220.1|UniProtKB=W5M2I2 W5M2I2 PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR phosphatase regulator activity#GO:0019208;molecular function activator activity#GO:0140677;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;enzyme activator activity#GO:0008047;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase activator#PC00182;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000012049.1|UniProtKB=W5N2H6 W5N2H6 PTHR12613:SF1 ERO1-RELATED ERO1-LIKE PROTEIN ALPHA protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001708.1|UniProtKB=W5M0R0 W5M0R0 PTHR24231:SF35 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 4-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010500.1|UniProtKB=W5MWW0 W5MWW0 PTHR45752:SF21 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 63 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004626.1|UniProtKB=W5MAY7 W5MAY7 PTHR23055:SF195 CALCIUM BINDING PROTEINS PHD FINGER PROTEIN 24 ISOFORM X1 cation binding#GO:0043169;molecular function activator activity#GO:0140677;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;enzyme activator activity#GO:0008047;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014290.1|UniProtKB=W5NAD2 W5NAD2 PTHR15454:SF47 NISCHARIN RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006178.1|UniProtKB=W5MGG4 W5MGG4 TNPO2 PTHR10527:SF17 IMPORTIN BETA TRANSPORTIN-2 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015611.1|UniProtKB=W5NF10 W5NF10 PTHR15176:SF1 NEPHROCYSTIN NEPHROCYSTIN-1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;anatomical structure morphogenesis#GO:0009653;epithelium development#GO:0060429;anatomical structure development#GO:0048856;developmental process#GO:0032502;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;cellular process#GO:0009987;tissue development#GO:0009888;protein localization#GO:0008104 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000014972.1|UniProtKB=W5NCS4 W5NCS4 PTHR22600:SF39 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT ALPHA hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;macromolecule metabolic process#GO:0043170;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010218.1|UniProtKB=W5MVW4 W5MVW4 PTHR43691:SF10 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 1 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 LEPOC|Ensembl=ENSLOCG00000004487.1|UniProtKB=W5MAF8 W5MAF8 PTHR15690:SF0 NUCLEAR RECEPTOR COACTIVATOR 6 NUCLEAR RECEPTOR COACTIVATOR 6 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008994.1|UniProtKB=W5MRE8 W5MRE8 PTHR21706:SF15 TRANSMEMBRANE PROTEIN 65 TRANSMEMBRANE PROTEIN 65 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017968.1|UniProtKB=W5NN62 W5NN62 PTHR11462:SF51 JUN TRANSCRIPTION FACTOR-RELATED JUNE PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000012776.1|UniProtKB=W5N510 W5N510 PTHR46771:SF3 DETERIN BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 Angiogenesis#P00005>Survivin#P00198 LEPOC|Ensembl=ENSLOCG00000001820.1|UniProtKB=W5M149 W5M149 PTHR45803:SF2 SOX100B TRANSCRIPTION FACTOR SOX-8 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;stem cell development#GO:0048864;epithelium development#GO:0060429;neural crest cell development#GO:0014032;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;negative regulation of nitrogen compound metabolic process#GO:0051172;mesenchymal cell differentiation#GO:0048762;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;stem cell differentiation#GO:0048863;morphogenesis of an epithelium#GO:0002009;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000012905.1|UniProtKB=W5N5J3 W5N5J3 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE LEPOC|Ensembl=ENSLOCG00000006497.1|UniProtKB=W5MHI8 W5MHI8 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006440.1|UniProtKB=W5MHC1 W5MHC1 PTHR10969:SF14 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEINS 1A_1B LIGHT CHAIN 3A cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;microtubule binding#GO:0008017;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000007004.1|UniProtKB=W5MJB9 W5MJB9 PTHR45752:SF13 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 58 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008761.1|UniProtKB=W5MQK4 W5MQK4 PTHR19143:SF272 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 ISOFORM X1 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008092.1|UniProtKB=W5MN66 W5MN66 PTHR28653:SF1 FAMILY NOT NAMED ATPASE SWSAP1 LEPOC|Ensembl=ENSLOCG00000011353.1|UniProtKB=W5N006 W5N006 PTHR46514:SF2 AMPHIPHYSIN AMPHIPHYSIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;synaptic vesicle recycling#GO:0036465;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015358.1|UniProtKB=W5NE41 W5NE41 PTHR47978:SF30 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;catabolic process#GO:0009056;autophagosome assembly#GO:0000045;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013877.1|UniProtKB=W5N905 W5N905 PTHR24410:SF21 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005024.1|UniProtKB=W5MCD7 W5MCD7 PTHR12002:SF177 CLAUDIN CLAUDIN-10-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000007171.1|UniProtKB=W5MJW5 W5MJW5 PTHR11639:SF119 S100 CALCIUM-BINDING PROTEIN PROTEIN S100 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000015279.1|UniProtKB=W5NDU2 W5NDU2 PTHR43108:SF9 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-ACETYLGLUCOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014235.1|UniProtKB=W5NA71 W5NA71 PTHR10794:SF45 ABHYDROLASE DOMAIN-CONTAINING PROTEIN MONOACYLGLYCEROL LIPASE ABHD2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 male gamete generation#GO:0048232;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;hormone-mediated signaling pathway#GO:0009755;carboxylic acid biosynthetic process#GO:0046394;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;spermatogenesis#GO:0007283;reproductive process#GO:0022414;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;organic acid biosynthetic process#GO:0016053;sperm capacitation#GO:0048240;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular response to endogenous stimulus#GO:0071495;monocarboxylic acid biosynthetic process#GO:0072330;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;cell communication#GO:0007154;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular response to steroid hormone stimulus#GO:0071383;developmental process#GO:0032502;response to lipid#GO:0033993;spermatid differentiation#GO:0048515;biosynthetic process#GO:0009058;cellular response to lipid#GO:0071396;acylglycerol catabolic process#GO:0046464;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;cellular response to organic cyclic compound#GO:0071407;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;steroid hormone mediated signaling pathway#GO:0043401;organic substance biosynthetic process#GO:1901576;glycerolipid catabolic process#GO:0046503;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;cell development#GO:0048468;spermatid development#GO:0007286;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;response to steroid hormone#GO:0048545 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;sperm flagellum#GO:0036126;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016067.1|UniProtKB=W5NGN8 W5NGN8 PTHR11848:SF159 TGF-BETA FAMILY NODAL HOMOLOG molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000000699.1|UniProtKB=W5LXC0 W5LXC0 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013803.1|UniProtKB=W5N8R7 W5N8R7 PTHR11035:SF20 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 3 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000000687.1|UniProtKB=W5LXA5 W5LXA5 PTHR24353:SF118 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE PROTEIN KINASE CGMP-DEPENDENT 3 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001175.1|UniProtKB=W5LYX0 W5LYX0 PTHR11848:SF249 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;regulation of cell population proliferation#GO:0042127;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000003023.1|UniProtKB=W5M5A1 W5M5A1 PTHR13809:SF6 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-10 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 LEPOC|Ensembl=ENSLOCG00000008508.1|UniProtKB=W5MPP4 W5MPP4 PTHR11132:SF293 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E4 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000782.1|UniProtKB=W5LXK9 W5LXK9 PTHR23266:SF269 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 6-1 binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000733.1|UniProtKB=W5LXG0 W5LXG0 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009509.1|UniProtKB=W5MTA7 W5MTA7 PTHR46608:SF2 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING 4 PRECURSOR lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014761.1|UniProtKB=W5NC23 W5NC23 PTHR21229:SF52 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87A PRECURSOR localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003887.1|UniProtKB=W5M8C8 W5M8C8 PTHR24178:SF21 MOLTING PROTEIN MLT-4 ANKYRIN REPEAT DOMAIN 52-RELATED protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;regulation of multicellular organismal process#GO:0051239;macromolecule localization#GO:0033036;regulation of muscle contraction#GO:0006937;regulation of heart contraction#GO:0008016;protein localization to membrane#GO:0072657;regulation of system process#GO:0044057;cellular process#GO:0009987;protein localization#GO:0008104;regulation of muscle system process#GO:0090257;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of biological process#GO:0050789;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;biological regulation#GO:0065007;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017812.1|UniProtKB=W5NMQ7 W5NMQ7 PTHR17602:SF4 RIBOSOME BIOGENESIS REGULATORY PROTEIN RIBOSOME BIOGENESIS REGULATORY PROTEIN HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004288.1|UniProtKB=W5M9R4 W5M9R4 PTHR23288:SF4 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell junction assembly#GO:0034329;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;cell-cell junction organization#GO:0045216;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;cell-cell junction assembly#GO:0007043;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;tight junction#GO:0070160;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;apical junction complex#GO:0043296;plasma membrane#GO:0005886 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000006424.1|UniProtKB=W5MHA5 W5MHA5 PTHR11689:SF136 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005465.1|UniProtKB=W5MDY0 W5MDY0 PTHR31428:SF7 RGM DOMAIN FAMILY MEMBER DRAG-1 RGM DOMAIN FAMILY ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014070.1|UniProtKB=W5N9N0 W5N9N0 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010771.1|UniProtKB=W5MXT4 W5MXT4 PTHR23322:SF105 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 8 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014523.1|UniProtKB=W5NB68 W5NB68 PTHR11537:SF174 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic membrane#GO:0045211;neuronal cell body#GO:0043025;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000001291.1|UniProtKB=W5LZA8 W5LZA8 PTHR24393:SF151 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005932.1|UniProtKB=W5MFK7 W5MFK7 PXDNL PTHR11475:SF38 OXIDASE/PEROXIDASE OXIDOREDUCTASE PXDNL-RELATED oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002070.1|UniProtKB=W5M1Z5 W5M1Z5 PTHR11037:SF18 TRANSCRIPTION FACTOR CP2 TRANSCRIPTION FACTOR CP2-LIKE PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001276.1|UniProtKB=W5LZ94 W5LZ94 PTHR11848:SF119 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000004570.1|UniProtKB=W5MAR6 W5MAR6 PTHR24145:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000012358.1|UniProtKB=W5N3L4 W5N3L4 PTHR11969:SF13 MAX DIMERIZATION, MAD MAX-INTERACTING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002128.1|UniProtKB=W5M272 W5M272 PTHR11576:SF16 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;oogenesis#GO:0048477;cellular process#GO:0009987;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000014665.1|UniProtKB=W5NBP2 W5NBP2 PTHR24238:SF69 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 165 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004204.1|UniProtKB=W5M9G2 W5M9G2 PTHR28474:SF1 TRANSMEMBRANE PROTEIN 72 TRANSMEMBRANE PROTEIN 72 LEPOC|Ensembl=ENSLOCG00000003460.1|UniProtKB=W5M6V9 W5M6V9 PTHR12655:SF0 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000017641.1|UniProtKB=W5NM87 W5NM87 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003303.1|UniProtKB=W5M698 W5M698 EIF3H PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000010785.1|UniProtKB=W5MXW4 W5MXW4 PTHR43016:SF13 PRESEQUENCE PROTEASE PRESEQUENCE PROTEASE, MITOCHONDRIAL metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015138.1|UniProtKB=W5NDC5 W5NDC5 PTHR22774:SF17 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3B LEPOC|Ensembl=ENSLOCG00000001484.1|UniProtKB=W5LZY5 W5LZY5 PTHR16932:SF18 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON, ALPHA-INDUCIBLE PROTEIN 27-LIKE 2 LEPOC|Ensembl=ENSLOCG00000010101.1|UniProtKB=W5MVF5 W5MVF5 PTHR12859:SF2 PRA1 PROTEIN PRA1 FAMILY PROTEIN 3 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;negative regulation of biological process#GO:0048519;negative regulation of transport#GO:0051051;regulation of transport#GO:0051049 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004892.1|UniProtKB=W5MBX5 W5MBX5 PTHR45656:SF1 PROTEIN CBR-CLEC-78 SEIZURE PROTEIN 6 HOMOLOG regulation of cell communication#GO:0010646;regulation of dendrite development#GO:0050773;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;cell junction organization#GO:0034330;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell body#GO:0044297;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cell projection#GO:0042995;dendritic spine#GO:0043197;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000000103.1|UniProtKB=W5LVG2 W5LVG2 PTHR23339:SF77 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;microtubule cytoskeleton organization#GO:0000226;positive regulation of cell cycle#GO:0045787;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell division#GO:0051302;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;positive regulation of cell division#GO:0051781;organelle assembly#GO:0070925;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;positive regulation of cell cycle process#GO:0090068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;organelle lumen#GO:0043233;cluster of actin-based cell projections#GO:0098862;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;kinocilium#GO:0060091;stereocilium bundle#GO:0032421;mitotic spindle#GO:0072686;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011951.1|UniProtKB=W5N237 W5N237 PTHR13989:SF33 REPLICATION PROTEIN A-RELATED CST COMPLEX SUBUNIT STN1 LEPOC|Ensembl=ENSLOCG00000012436.1|UniProtKB=W5N3V3 W5N3V3 PTHR11606:SF13 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 LEPOC|Ensembl=ENSLOCG00000005403.1|UniProtKB=W5MDR6 W5MDR6 PTHR46099:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN RECEPTOR TYPE B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;system process#GO:0003008;pigmentation#GO:0043473;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;developmental pigmentation#GO:0048066;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>ET-RA/B#P00580 LEPOC|Ensembl=ENSLOCG00000013849.1|UniProtKB=W5N8X5 W5N8X5 PTHR45712:SF2 AGAP008170-PA ASPORIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000001101.1|UniProtKB=W5LYN3 W5LYN3 PTHR11685:SF435 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19B ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000264.1|UniProtKB=W5LVY1 W5LVY1 PTHR23267:SF477 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;production of molecular mediator of immune response#GO:0002440;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013945.1|UniProtKB=W5N988 W5N988 PTHR10865:SF5 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;enzyme binding#GO:0019899;protein binding#GO:0005515 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010537.1|UniProtKB=W5MX03 W5MX03 PTHR13891:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 LEPOC|Ensembl=ENSLOCG00000011031.1|UniProtKB=W5MYT6 W5MYT6 SPAG17 PTHR21963:SF1 PF6 SPERM-ASSOCIATED ANTIGEN 17 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000001667.1|UniProtKB=W5M0M5 W5M0M5 PTHR21433:SF1 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA ION CHANNEL TACAN cellular developmental process#GO:0048869;cell differentiation#GO:0030154;fat cell differentiation#GO:0045444;cellular process#GO:0009987;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000423.1|UniProtKB=W5LWK3 W5LWK3 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000008305.1|UniProtKB=W5MNY0 W5MNY0 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000010621.1|UniProtKB=W5MX99 W5MX99 GPATCH2L PTHR14195:SF3 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2-LIKE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018107.1|UniProtKB=W5NNJ9 W5NNJ9 ITPRIPL2 PTHR10656:SF9 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 2 transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012387.1|UniProtKB=W5N3P5 W5N3P5 PTHR44324:SF3 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 49-LIKE LEPOC|Ensembl=ENSLOCG00000001853.1|UniProtKB=W5M188 W5M188 PTHR10985:SF79 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000007220.1|UniProtKB=W5MK28 W5MK28 PTHR11422:SF6 T-CELL SURFACE GLYCOPROTEIN CD4 HEMICENTIN-1 ISOFORM X1 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000032.1|UniProtKB=W5LV79 W5LV79 PTHR24243:SF7 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006987.1|UniProtKB=W5MJA9 W5MJA9 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000115.1|UniProtKB=W5LVH0 W5LVH0 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009237.1|UniProtKB=W5MSA6 W5MSA6 PTHR24119:SF0 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168 LEPOC|Ensembl=ENSLOCG00000000713.1|UniProtKB=W5LXD5 W5LXD5 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011914.1|UniProtKB=W5N1Y9 W5N1Y9 PTHR24237:SF37 G-PROTEIN COUPLED RECEPTOR COAGULATION FACTOR II (THROMBIN) RECEPTOR-LIKE 2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009721.1|UniProtKB=W5MU31 W5MU31 PTHR13800:SF15 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 6 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005407.1|UniProtKB=W5MDR3 W5MDR3 PTHR45665:SF11 AQUAPORIN-8 AQUAPORIN 8B-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011063.1|UniProtKB=W5MYX3 W5MYX3 PTHR45660:SF13 HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000000026.1|UniProtKB=W5LV73 W5LV73 PTHR24115:SF534 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007875.1|UniProtKB=W5MMH0 W5MMH0 PTHR12533:SF5 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;calcineurin-mediated signaling#GO:0097720;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367 LEPOC|Ensembl=ENSLOCG00000015776.1|UniProtKB=W5NFL3 W5NFL3 PTHR24126:SF24 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007725.1|UniProtKB=W5MLX0 W5MLX0 PTHR10106:SF12 CYTOCHROME B561-RELATED PLASMA MEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYBRD1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009261.1|UniProtKB=W5MSE7 W5MSE7 PTHR11984:SF117 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000008307.1|UniProtKB=W5MNY5 W5MNY5 PTHR14336:SF4 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 1 LEPOC|Ensembl=ENSLOCG00000001747.1|UniProtKB=W5M0W0 W5M0W0 PTHR12294:SF3 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 2, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;cation channel complex#GO:0034703;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003797.1|UniProtKB=W5M822 W5M822 PTHR28591:SF1 LATEXIN LATEXIN peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003774.1|UniProtKB=W5M7Z0 W5M7Z0 PTHR12622:SF41 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3L transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014169.1|UniProtKB=W5N9Z6 W5N9Z6 PTHR12092:SF2 PLECKSTRIN PLECKSTRIN-2 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003605.1|UniProtKB=W5M7D6 W5M7D6 PTHR48067:SF1 GPI-ANCHOR TRANSAMIDASE GPI-ANCHOR TRANSAMIDASE hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000010219.1|UniProtKB=W5MVV1 W5MVV1 PTHR24067:SF246 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 B ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;protein-DNA complex#GO:0032993;chromosome#GO:0005694;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000016777.1|UniProtKB=W5NJC8 W5NJC8 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000006179.1|UniProtKB=W5MGH3 W5MGH3 PTHR16943:SF11 2-METHYLCITRATE DEHYDRATASE-RELATED CIS-ACONITATE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 response to stimulus#GO:0050896;response to stress#GO:0006950;defense response#GO:0006952 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001438.1|UniProtKB=W5LZU4 W5LZU4 PTHR46708:SF1 TENASCIN TENASCIN cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of cell adhesion#GO:0030155 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017705.1|UniProtKB=W5NMF1 W5NMF1 PTHR11711:SF322 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf6#P00919;Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000000043.1|UniProtKB=W5LV94 W5LV94 PTHR45622:SF56 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002024.1|UniProtKB=W5M1V2 W5M1V2 PTHR24055:SF584 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>MAPK1#P07166;CCKR signaling map#P06959>MAPK1/3#P07228;EGF receptor signaling pathway#P00018>ERK1-2#P00543;B cell activation#P00010>ERK#P00371;VEGF signaling pathway#P00056>MEK#P01402;Toll receptor signaling pathway#P00054>ERK2#P01356;Interleukin signaling pathway#P00036>ERK#P00965;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>ERK1-2#P00627;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Angiogenesis#P00005>Erk#P00203;VEGF signaling pathway#P00056>Erk#P01407;Apoptosis signaling pathway#P00006>MAPK#P00269;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;T cell activation#P00053>ERK#P01300;Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEK#P00225;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;Ras Pathway#P04393>ERK#P04542;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 LEPOC|Ensembl=ENSLOCG00000004940.1|UniProtKB=W5MC35 W5MC35 PTHR24103:SF602 E3 UBIQUITIN-PROTEIN LIGASE TRIM RESTIN HOMOLOG ISOFORM X2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000018306.1|UniProtKB=W5NP48 W5NP48 SLC35A4 PTHR10231:SF43 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A4-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006751.1|UniProtKB=W5MIE8 W5MIE8 PTHR19960:SF25 TEKTIN TEKTIN-1 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000004292.1|UniProtKB=W5M9R7 W5M9R7 PTHR10218:SF130 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-12 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;dopamine receptor binding#GO:0050780;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 membrane protein complex#GO:0098796;brush border#GO:0005903;cluster of actin-based cell projections#GO:0098862;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000006013.1|UniProtKB=W5MFW8 W5MFW8 PTHR11793:SF7 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR E2-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000013713.1|UniProtKB=W5N8G8 W5N8G8 PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mRNA modification#GO:0016556;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000002660.1|UniProtKB=W5M419 W5M419 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005397.1|UniProtKB=W5MDP7 W5MDP7 PTHR45665:SF6 AQUAPORIN-8 AQP8A PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000016173.1|UniProtKB=W5NH30 W5NH30 PTHR47735:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016534.1|UniProtKB=W5NIG4 W5NIG4 PTHR24102:SF18 PHD FINGER PROTEIN PHD FINGER PROTEIN 21B LEPOC|Ensembl=ENSLOCG00000012722.1|UniProtKB=W5N4V0 W5N4V0 PNMT PTHR10867:SF18 NNMT/PNMT/TEMT FAMILY MEMBER PHENYLETHANOLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 LEPOC|Ensembl=ENSLOCG00000014865.1|UniProtKB=W5NCF1 W5NCF1 PTHR24213:SF17 ACTIN-BINDING LIM PROTEIN DEMATIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017590.1|UniProtKB=W5NM36 W5NM36 PTHR10361:SF3 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004531.1|UniProtKB=W5MAL0 W5MAL0 PTHR22978:SF6 B-CELL TRANSLOCATION GENE PROTEIN BTG3 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004643.1|UniProtKB=W5MB13 W5MB13 PTHR12706:SF5 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 2 nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008610.1|UniProtKB=W5MQ09 W5MQ09 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;cation channel complex#GO:0034703;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002247.1|UniProtKB=W5M2L0 W5M2L0 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003033.1|UniProtKB=W5M5C3 W5M5C3 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000001006.1|UniProtKB=W5LYC5 W5LYC5 SLC22A17 PTHR24064:SF216 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 17 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007816.1|UniProtKB=W5MM84 W5MM84 PTHR11679:SF33 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 3 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000004904.1|UniProtKB=W5MBY8 W5MBY8 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004694.1|UniProtKB=W5MB68 W5MB68 PTHR23236:SF27 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EMBRYONIC POLYADENYLATE-BINDING PROTEIN 2 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000014601.1|UniProtKB=W5NBG0 W5NBG0 PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;chromatin binding#GO:0003682;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000005795.1|UniProtKB=W5MF41 W5MF41 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017848.1|UniProtKB=W5NMU2 W5NMU2 PTHR22796:SF6 URG4-RELATED INTERFERON-INDUCED VERY LARGE GTPASE 1-RELATED LEPOC|Ensembl=ENSLOCG00000013116.1|UniProtKB=W5N6A3 W5N6A3 PTHR12751:SF6 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;stress fiber assembly#GO:0043149;contractile actin filament bundle assembly#GO:0030038;actin filament bundle assembly#GO:0051017;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000002303.1|UniProtKB=W5M2T1 W5M2T1 PTHR11969:SF4 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003742.1|UniProtKB=W5M7V0 W5M7V0 PTHR13103:SF2 SCHWANNOMIN INTERACTING PROTEIN 1 IQCJ-SCHIP1 READTHROUGH TRANSCRIPT PROTEIN-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008094.1|UniProtKB=W5MN82 W5MN82 SELENOP PTHR10105:SF3 SELENOPROTEIN P SELENOPROTEIN P small molecule binding#GO:0036094;binding#GO:0005488 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000004575.1|UniProtKB=W5MAS8 W5MAS8 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 PDGF signaling pathway#P00047>c-Jun#P01163 LEPOC|Ensembl=ENSLOCG00000000824.1|UniProtKB=W5LXR0 W5LXR0 PTHR10032:SF272 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS OVO-LIKE ZINC FINGER 1A-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;epidermal cell differentiation#GO:0009913;regulation of DNA-templated transcription#GO:0006355;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;epidermis development#GO:0008544;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002658.1|UniProtKB=W5M425 W5M425 PTHR15742:SF3 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 1 LEPOC|Ensembl=ENSLOCG00000002270.1|UniProtKB=W5M2P5 W5M2P5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013357.1|UniProtKB=W5N759 W5N759 PTHR10202:SF18 PRESENILIN PRESENILIN-1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein processing#GO:0016485;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling#GO:0023052;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;membrane protein proteolysis#GO:0033619;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cell communication#GO:0007154;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;membrane protein ectodomain proteolysis#GO:0006509;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;Notch signaling pathway#GO:0007219 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 aspartic protease#PC00053;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Notch signaling pathway#P00045>Presenilin#P01110;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098 LEPOC|Ensembl=ENSLOCG00000008786.1|UniProtKB=W5MQN9 W5MQN9 PTHR16140:SF0 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013159.1|UniProtKB=W5N6F6 W5N6F6 PTHR10574:SF197 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 ISOFORM X1 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008868.1|UniProtKB=W5MQY7 W5MQY7 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016324.1|UniProtKB=W5NHP4 W5NHP4 PTHR15657:SF1 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006541.1|UniProtKB=W5MHP5 W5MHP5 PTHR24078:SF553 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;chaperone cofactor-dependent protein refolding#GO:0051085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005324.1|UniProtKB=W5MDG2 W5MDG2 PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000009573.1|UniProtKB=W5MTJ4 W5MTJ4 PTHR11271:SF6 GUANINE DEAMINASE GUANINE DEAMINASE cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;deaminase activity#GO:0019239;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 Purine metabolism#P02769>Guanine Deaminase#P03118;Xanthine and guanine salvage pathway#P02788>Guanine deaminase#P03249 LEPOC|Ensembl=ENSLOCG00000011685.1|UniProtKB=W5N151 W5N151 ALX3 PTHR24329:SF578 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000016809.1|UniProtKB=W5NJH4 W5NJH4 PTHR10807:SF43 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 5 nucleoside-triphosphatase regulator activity#GO:0060589;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;GTPase regulator activity#GO:0030695;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;guanyl-nucleotide exchange factor activity#GO:0005085 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000010146.1|UniProtKB=W5MVL2 W5MVL2 PTHR23043:SF7 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;response to oxygen levels#GO:0070482 basic helix-loop-helix transcription factor#PC00055 VEGF signaling pathway#P00056>HIF-1#P01401;Angiogenesis#P00005>HIF-1#P00214;Hypoxia response via HIF activation#P00030>HIF-1alpha#P00818 LEPOC|Ensembl=ENSLOCG00000000822.1|UniProtKB=W5LXQ6 W5LXQ6 PTHR21844:SF2 AKT1 SUBSTRATE 1 PROTEIN PROLINE-RICH AKT1 SUBSTRATE 1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CCKR signaling map#P06959>PRAS40#P07076 LEPOC|Ensembl=ENSLOCG00000015332.1|UniProtKB=W5NE14 W5NE14 PTHR10027:SF33 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1-RELATED monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010697.1|UniProtKB=W5MXJ1 W5MXJ1 PTHR20842:SF0 PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE ALPHA-ASPARTYL DIPEPTIDASE serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000005307.1|UniProtKB=W5MDF1 W5MDF1 PTHR11690:SF297 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 1B monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017606.1|UniProtKB=W5NM52 W5NM52 PTHR24229:SF35 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 4 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to steroid hormone#GO:0048545 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000014467.1|UniProtKB=W5NB02 W5NB02 PTHR22748:SF27 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2 hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008185.1|UniProtKB=W5MNH8 W5MNH8 PTHR13439:SF1 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 4 lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014508.1|UniProtKB=W5NB48 W5NB48 PTHR13944:SF18 AGAP007712-PA A-KINASE ANCHOR PROTEIN 13 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008067.1|UniProtKB=W5MN50 W5MN50 PTHR19288:SF44 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014468.1|UniProtKB=W5NB04 W5NB04 PTHR24356:SF365 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C DELTA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PKC#P00565;Apoptosis signaling pathway#P00006>PKCs#P00318;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Gonadotropin-releasing hormone receptor pathway#P06664>nPKCs#P06852;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;B cell activation#P00010>PKC#P00373;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;CCKR signaling map#P06959>PKCdelta#P07134;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 LEPOC|Ensembl=ENSLOCG00000002536.1|UniProtKB=W5M3M5 W5M3M5 PTHR16083:SF39 LEUCINE RICH REPEAT CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LRSAM1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009975.1|UniProtKB=W5MUY9 W5MUY9 PTHR12247:SF139 POLYCOMB GROUP PROTEIN ATHERIN-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007603.1|UniProtKB=W5MLG4 W5MLG4 PTHR24173:SF29 ANKYRIN REPEAT CONTAINING PHOTORECEPTOR ANKYRIN REPEAT PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007748.1|UniProtKB=W5MM01 W5MM01 PTHR10026:SF45 CYCLIN CYCLIN-L2 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000012321.1|UniProtKB=W5N3F4 W5N3F4 PTHR10829:SF1 CORTACTIN AND DREBRIN DREBRIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;positive regulation of growth#GO:0045927;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;regulation of synapse structure or activity#GO:0050803;positive regulation of multicellular organismal process#GO:0051240;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;regulation of postsynapse organization#GO:0099175;regulation of cell growth#GO:0001558;regulation of anatomical structure size#GO:0090066;postsynapse organization#GO:0099173;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;regulation of cell size#GO:0008361;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000018098.1|UniProtKB=W5NNJ0 W5NNJ0 PTHR11467:SF182 HISTONE H1 HISTONE H1.0 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;chromosome condensation#GO:0030261;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA recombination#GO:0000018;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011585.1|UniProtKB=W5N0S6 W5N0S6 PTHR28664:SF2 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 BRAIN-ENRICHED GUANYLATE KINASE-ASSOCIATED PROTEIN regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of system process#GO:0044057 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000013092.1|UniProtKB=W5N677 W5N677 PTHR45627:SF26 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 1 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 CCKR signaling map#P06959>Adenylate cyclase#P07127;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Gonadotropin-releasing hormone receptor pathway#P06664>AC#P06699;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 LEPOC|Ensembl=ENSLOCG00000006255.1|UniProtKB=W5MGQ7 W5MGQ7 PTHR12771:SF16 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 3 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006962.1|UniProtKB=W5MJ70 W5MJ70 PTHR10404:SF26 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 1 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;intracellular iron ion homeostasis#GO:0006879;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015804.1|UniProtKB=W5NFP6 W5NFP6 PTHR13480:SF0 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE HAKAI transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012159.1|UniProtKB=W5N2V0 W5N2V0 PTHR11129:SF1 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein modification process#GO:0036211;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000123.1|UniProtKB=W5LVH9 W5LVH9 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011699.1|UniProtKB=W5N167 W5N167 PTHR11537:SF246 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 2-LIKE-RELATED monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;presynaptic membrane#GO:0042734;cell leading edge#GO:0031252;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;distal axon#GO:0150034;postsynapse#GO:0098794;cell projection#GO:0042995;membrane protein complex#GO:0098796;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell projection membrane#GO:0031253;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell body#GO:0044297;neuron projection#GO:0043005;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004160.1|UniProtKB=W5M9C2 W5M9C2 PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006825.1|UniProtKB=W5MIP0 W5MIP0 PTHR31612:SF2 MULTIVESICULAR BODY SUBUNIT 12A MULTIVESICULAR BODY SUBUNIT 12A endosomal transport#GO:0016197;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;cellular localization#GO:0051641;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;transport#GO:0006810;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;lysosomal transport#GO:0007041;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;endosome transport via multivesicular body sorting pathway#GO:0032509;biological regulation#GO:0065007;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of ERBB signaling pathway#GO:1901184;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytosol#GO:0005829;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000010931.1|UniProtKB=W5MYE8 W5MYE8 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 LEPOC|Ensembl=ENSLOCG00000007326.1|UniProtKB=W5MKG1 W5MKG1 PTHR20939:SF1 SORTING NEXIN 20, 21 SORTING NEXIN-20 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001228.1|UniProtKB=W5LZ47 W5LZ47 PTHR11909:SF157 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;positive regulation of signal transduction#GO:0009967;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;import into cell#GO:0098657 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000013058.1|UniProtKB=W5N622 W5N622 PTHR12842:SF4 FI01459P PROTEIN NOXP20 LEPOC|Ensembl=ENSLOCG00000017099.1|UniProtKB=W5NKH2 W5NKH2 PTHR13318:SF152 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000001983.1|UniProtKB=W5M1Q0 W5M1Q0 PTHR15138:SF22 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TAFH DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000009224.1|UniProtKB=W5MS95 W5MS95 PTHR19282:SF159 TETRASPANIN TETRASPANIN-15 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000811.1|UniProtKB=W5LXP1 W5LXP1 PTHR23266:SF390 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;immune system process#GO:0002376;adaptive immune response#GO:0002250;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012925.1|UniProtKB=W5N5K3 W5N5K3 PTHR31872:SF5 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 LEPOC|Ensembl=ENSLOCG00000001136.1|UniProtKB=W5LYT0 W5LYT0 PTHR12758:SF19 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015604.1|UniProtKB=W5NF03 W5NF03 CPA1 PTHR11705:SF94 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A1 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004246.1|UniProtKB=W5M9M2 W5M9M2 C8orf34 PTHR32000:SF3 SIMILAR TO HYPOTHETICAL PROTEIN RIKEN CDNA A830018L16 GENE LEPOC|Ensembl=ENSLOCG00000007255.1|UniProtKB=W5MK71 W5MK71 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000004655.1|UniProtKB=W5MB20 W5MB20 PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 LEPOC|Ensembl=ENSLOCG00000006436.1|UniProtKB=W5MHB4 W5MHB4 PTHR17601:SF3 RAFTLIN-RELATED RAFTLIN LEPOC|Ensembl=ENSLOCG00000003008.1|UniProtKB=W5M590 W5M590 L3MBTL4 PTHR12247:SF78 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001402.1|UniProtKB=W5LZP2 W5LZP2 PTHR14932:SF1 RAS GTPASE-RELATED RAB-LIKE PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000007577.1|UniProtKB=W5MLD2 W5MLD2 PTHR23235:SF28 KRUEPPEL-LIKE TRANSCRIPTION FACTOR SP5 TRANSCRIPTION FACTOR-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007102.1|UniProtKB=W5MJR0 W5MJR0 PTHR23182:SF3 BREAKPOINT CLUSTER REGION PROTEIN BCR BREAKPOINT CLUSTER REGION PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012739.1|UniProtKB=W5N4W3 W5N4W3 PTHR24161:SF17 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005029.1|UniProtKB=W5MCF0 W5MCF0 PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016228.1|UniProtKB=W5NHA1 W5NHA1 PTHR48023:SF2 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 12 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;system development#GO:0048731;circulatory system development#GO:0072359;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011638.1|UniProtKB=W5N0Y9 W5N0Y9 RPL10A PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005625.1|UniProtKB=W5MEJ3 W5MEJ3 PTHR24412:SF174 KELCH PROTEIN KELCH-LIKE ECH-ASSOCIATED PROTEIN 1A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005977.1|UniProtKB=W5MFR1 W5MFR1 PTHR23257:SF706 SERINE-THREONINE PROTEIN KINASE PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE MOS transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016930.1|UniProtKB=W5NJX2 W5NJX2 PTHR12748:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear pre-replicative complex#GO:0005656;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000009149.1|UniProtKB=W5MRZ7 W5MRZ7 PTHR10194:SF52 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN NGAP G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000017321.1|UniProtKB=W5NLB7 W5NLB7 RASSF10 PTHR15286:SF13 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 10 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008617.1|UniProtKB=W5MQ18 W5MQ18 RPS3A PTHR11830:SF0 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015516.1|UniProtKB=W5NEN5 W5NEN5 PTHR22748:SF6 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 LEPOC|Ensembl=ENSLOCG00000013562.1|UniProtKB=W5N7W1 W5N7W1 PTHR22923:SF93 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013924.1|UniProtKB=W5N955 W5N955 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein lipidation#GO:0006497;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;cellular response to stress#GO:0033554;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000003807.1|UniProtKB=W5M865 W5M865 PTHR24023:SF845 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000006676.1|UniProtKB=W5MI50 W5MI50 PTHR44755:SF11 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide hormone binding#GO:0017046;hormone binding#GO:0042562;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014162.1|UniProtKB=W5N9Y8 W5N9Y8 PTHR13589:SF4 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 3 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015364.1|UniProtKB=W5NE48 W5NE48 PTHR10625:SF43 HISTONE DEACETYLASE HDAC1-RELATED POLYAMINE DEACETYLASE HDAC10 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000000520.1|UniProtKB=W5LWS9 W5LWS9 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING GASTRULA ZINC FINGER PROTEIN XLCGF8.2DB-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016220.1|UniProtKB=W5NH91 W5NH91 PTHR19346:SF3 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F3 LEPOC|Ensembl=ENSLOCG00000013714.1|UniProtKB=W5N8F2 W5N8F2 PTHR23235:SF23 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP6 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017429.1|UniProtKB=W5NLM5 W5NLM5 PTHR12002:SF191 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000016070.1|UniProtKB=W5NGP2 W5NGP2 PTHR11848:SF159 TGF-BETA FAMILY NODAL HOMOLOG molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000011921.1|UniProtKB=W5N1Z6 W5N1Z6 PTHR31594:SF16 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN SI:CH211-281L24.3 LEPOC|Ensembl=ENSLOCG00000010558.1|UniProtKB=W5MX30 W5MX30 PTHR48050:SF13 STEROL 3-BETA-GLUCOSYLTRANSFERASE STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007910.1|UniProtKB=W5MMJ9 W5MMJ9 PTHR24089:SF262 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A24 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017536.1|UniProtKB=W5NLY2 W5NLY2 MACIR PTHR31224:SF2 UNC119-BINDING PROTEIN C5ORF30 MACROPHAGE IMMUNOMETABOLISM REGULATOR regulation of cytokine production#GO:0001817;negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of cell motility#GO:2000145;negative regulation of biosynthetic process#GO:0009890;regulation of locomotion#GO:0040012;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular biosynthetic process#GO:0031326;regulation of cell migration#GO:0030334;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cell migration#GO:0030336;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000006599.1|UniProtKB=W5MHW4 W5MHW4 PTHR12178:SF2 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 2 regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of protein metabolic process#GO:0051246;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017334.1|UniProtKB=W5NLD0 W5NLD0 PTHR21338:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L41 LARGE RIBOSOMAL SUBUNIT PROTEIN ML41 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001354.1|UniProtKB=W5LZH9 W5LZH9 PTHR11588:SF492 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011368.1|UniProtKB=W5N020 W5N020 PTHR12768:SF4 BECLIN 1 BECLIN-1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;transport#GO:0006810;mitophagy#GO:0000423;late endosome to vacuole transport#GO:0045324;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;establishment of localization#GO:0051234;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000006038.1|UniProtKB=W5MFY2 W5MFY2 PTHR10838:SF8 SYNAPTOGYRIN SYNAPTOGYRIN-3 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008428.1|UniProtKB=W5MPE0 W5MPE0 PTHR45713:SF11 FTP DOMAIN-CONTAINING PROTEIN FUCOLECTIN TACHYLECTIN-4 PENTRAXIN-1 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011313.1|UniProtKB=W5MZU2 W5MZU2 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011421.1|UniProtKB=W5N076 W5N076 PTHR12622:SF37 DELTEX-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011742.1|UniProtKB=W5N1D0 W5N1D0 PTHR13284:SF9 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009480.1|UniProtKB=W5MT74 W5MT74 PTHR23197:SF10 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING TARGET OF NESH-SH3 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;positive regulation of cell-substrate adhesion#GO:0010811;external encapsulating structure organization#GO:0045229;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular component organization#GO:0016043;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;extracellular matrix organization#GO:0030198;positive regulation of biological process#GO:0048518;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cellular process#GO:0048522 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 LEPOC|Ensembl=ENSLOCG00000017083.1|UniProtKB=W5NKF5 W5NKF5 PTHR43184:SF12 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B SUGAR PHOSPHATE EXCHANGER 3 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010834.1|UniProtKB=W5MY33 W5MY33 PTHR11615:SF6 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014637.1|UniProtKB=W5NBK7 W5NBK7 PTHR10024:SF351 SYNAPTOTAGMIN SYNAPTOTAGMIN-4-LIKE cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003743.1|UniProtKB=W5M7W8 W5M7W8 PTHR12974:SF46 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5B adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of gene expression#GO:0010628;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;RNA stabilization#GO:0043489;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 LEPOC|Ensembl=ENSLOCG00000005012.1|UniProtKB=W5MCC6 W5MCC6 PTHR45619:SF67 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;mitotic cell cycle phase transition#GO:0044772;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000015685.1|UniProtKB=W5NFA5 W5NFA5 PTHR45850:SF5 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;import into cell#GO:0098657;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008229.1|UniProtKB=W5MNN3 W5MNN3 PTHR12411:SF969 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN O cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003411.1|UniProtKB=W5M6N0 W5M6N0 PTHR14564:SF2 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC26 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000010518.1|UniProtKB=W5MWX8 W5MWX8 PTHR15507:SF16 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 654 nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001088.1|UniProtKB=W5LYM1 W5LYM1 PTHR12911:SF22 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 envelope#GO:0031975;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014066.1|UniProtKB=W5N9M8 W5N9M8 PTHR15574:SF43 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 5 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015375.1|UniProtKB=W5NE62 W5NE62 PNPT1 PTHR11252:SF0 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;transferase activity#GO:0016740;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006372.1|UniProtKB=W5MH36 W5MH36 PTHR11461:SF84 SERINE PROTEASE INHIBITOR, SERPIN PIGMENT EPITHELIUM-DERIVED FACTOR peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of molecular function#GO:0065009;regulation of vasculature development#GO:1901342;regulation of hydrolase activity#GO:0051336;regulation of proteolysis#GO:0030162;regulation of multicellular organismal process#GO:0051239;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;negative regulation of angiogenesis#GO:0016525;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000015634.1|UniProtKB=W5NF38 W5NF38 PTHR21588:SF18 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000000422.1|UniProtKB=W5LWF4 W5LWF4 PTHR10811:SF110 FRINGE-RELATED BETA-1,3-GLUCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017274.1|UniProtKB=W5NL57 W5NL57 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 positive regulation of gene expression#GO:0010628;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000003715.1|UniProtKB=W5M7R4 W5M7R4 PTHR21508:SF3 MITOGUARDIN MITOGUARDIN 1 mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;organelle fusion#GO:0048284 LEPOC|Ensembl=ENSLOCG00000006948.1|UniProtKB=W5MJ53 W5MJ53 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676;Huntington disease#P00029>GAPDH#P00810 LEPOC|Ensembl=ENSLOCG00000003252.1|UniProtKB=W5M633 W5M633 MATCAP1 PTHR31817:SF1 FAMILY NOT NAMED MICROTUBULE-ASSOCIATED TYROSINE CARBOXYPEPTIDASE 1 LEPOC|Ensembl=ENSLOCG00000012474.1|UniProtKB=W5N420 W5N420 PTHR10199:SF78 THROMBOSPONDIN THROMBOSPONDIN-1 regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;biological regulation#GO:0065007;negative regulation of angiogenesis#GO:0016525;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023 cell adhesion molecule#PC00069 p53 pathway#P00059>TSP1#G01566 LEPOC|Ensembl=ENSLOCG00000017577.1|UniProtKB=W5NM23 W5NM23 PTHR26453:SF724 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012574.1|UniProtKB=W5N4D7 W5N4D7 PTHR45673:SF3 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;calcineurin-mediated signaling#GO:0097720;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006037.1|UniProtKB=W5MFY0 W5MFY0 PTHR19338:SF7 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8 B LEPOC|Ensembl=ENSLOCG00000011787.1|UniProtKB=W5N1I3 W5N1I3 PTHR11249:SF3 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR BETA protein-containing complex binding#GO:0044877;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010414.1|UniProtKB=W5MWL0 W5MWL0 PTHR11487:SF0 THIOESTERASE S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN lipid metabolic process#GO:0006629;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000017341.1|UniProtKB=W5NLD7 W5NLD7 PTHR23048:SF30 MYOSIN LIGHT CHAIN 1, 3 CARDIAC MYOSIN LIGHT CHAIN-1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000540.1|UniProtKB=W5LWT7 W5LWT7 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune response-activating signaling pathway#GO:0002757;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008930.1|UniProtKB=W5MR66 W5MR66 PTHR22894:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012074.1|UniProtKB=W5N2J5 W5N2J5 PTHR46588:SF1 SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN protein binding#GO:0005515;binding#GO:0005488 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of signaling#GO:0023051;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;regulation of response to stimulus#GO:0048583;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of proteolysis involved in protein catabolic process#GO:1903051;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000016413.1|UniProtKB=W5NI14 W5NI14 PTHR48041:SF113 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 ATP-binding cassette (ABC) transporter complex#GO:0043190;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010757.1|UniProtKB=W5MXS1 W5MXS1 PTHR11329:SF0 LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 LEUKOCYTE CELL-DERIVED CHEMOTAXIN-2 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000010045.1|UniProtKB=W5MV76 W5MV76 METTL21C PTHR14614:SF13 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE METHYLTRANSFERASE METTL21C protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006293.1|UniProtKB=W5MGT9 W5MGT9 PTHR16967:SF1 LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000008109.1|UniProtKB=W5MN90 W5MN90 PTHR12899:SF3 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008713.1|UniProtKB=W5MQE9 W5MQE9 PTHR10638:SF3 COPPER AMINE OXIDASE AMILORIDE-SENSITIVE AMINE OXIDASE [COPPER-CONTAINING] cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 organonitrogen compound metabolic process#GO:1901564;amine metabolic process#GO:0009308;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 LEPOC|Ensembl=ENSLOCG00000017994.1|UniProtKB=W5NN86 W5NN86 PTHR48164:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008987.1|UniProtKB=W5MRE1 W5MRE1 PTHR23049:SF8 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN LIGHT CHAIN 5 cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009633.1|UniProtKB=W5MTR6 W5MTR6 PTHR12995:SF3 FI21814P1 TRANSMEMBRANE PROTEIN 39A negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;negative regulation of cellular catabolic process#GO:0031330;regulation of protein-containing complex disassembly#GO:0043244;regulation of cellular component organization#GO:0051128;regulation of macroautophagy#GO:0016241;negative regulation of metabolic process#GO:0009892;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;regulation of biological process#GO:0050789;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of organelle assembly#GO:1902115;negative regulation of protein-containing complex disassembly#GO:0043242;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;regulation of autophagosome maturation#GO:1901096;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001030.1|UniProtKB=W5LYF0 W5LYF0 PTHR47115:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 LEPOC|Ensembl=ENSLOCG00000001277.1|UniProtKB=W5LZ90 W5LZ90 PTHR23049:SF34 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT POLYPEPTIDE 9 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002962.1|UniProtKB=W5M553 W5M553 PTHR31167:SF3 SPINDLE AND CENTRIOLE ASSOCIATED PROTEIN 1 SPICE1 SPINDLE AND CENTRIOLE-ASSOCIATED PROTEIN 1 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;mitotic spindle assembly#GO:0090307;regulation of organelle assembly#GO:1902115;spindle assembly#GO:0051225;regulation of centriole replication#GO:0046599;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;establishment of organelle localization#GO:0051656;regulation of centrosome duplication#GO:0010824;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;establishment of chromosome localization#GO:0051303;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;localization#GO:0051179;organelle assembly#GO:0070925;regulation of centrosome cycle#GO:0046605;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012858.1|UniProtKB=W5N5B8 W5N5B8 PTHR23285:SF5 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3B RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002039.1|UniProtKB=W5M1V4 W5M1V4 PTHR24231:SF14 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SUCCINATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012751.1|UniProtKB=W5N4X9 W5N4X9 PTHR12560:SF62 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 3 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007401.1|UniProtKB=W5MKS4 W5MKS4 PTHR46875:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016165.1|UniProtKB=W5NH11 W5NH11 PTHR43788:SF6 DNA2/NAM7 HELICASE FAMILY MEMBER DNA HELICASE B DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005785.1|UniProtKB=W5MF28 W5MF28 PTHR43903:SF1 NEUROLIGIN BILE SALT-ACTIVATED LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;signaling receptor activity#GO:0038023;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;triglyceride lipase activity#GO:0004806 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;system process#GO:0003008;lipid catabolic process#GO:0016042;nervous system development#GO:0007399;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;synaptic signaling#GO:0099536;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;regulation of body fluid levels#GO:0050878;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;membrane lipid metabolic process#GO:0006643;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;import into cell#GO:0098657;lipid metabolic process#GO:0006629;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;sphingolipid metabolic process#GO:0006665;system development#GO:0048731;synaptic vesicle recycling#GO:0036465;membrane assembly#GO:0071709;catabolic process#GO:0009056;cell junction assembly#GO:0034329;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;amide metabolic process#GO:0043603;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;localization#GO:0051179;digestion#GO:0007586;synapse assembly#GO:0007416;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;cellular lipid metabolic process#GO:0044255;vesicle-mediated transport in synapse#GO:0099003 cell junction#GO:0030054;cell surface#GO:0009986;synapse#GO:0045202;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004784.1|UniProtKB=W5MBJ2 W5MBJ2 PTHR11616:SF133 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003249.1|UniProtKB=W5M627 W5M627 PTHR24260:SF136 FAMILY NOT NAMED GH08193P-RELATED LEPOC|Ensembl=ENSLOCG00000017920.1|UniProtKB=W5NN14 W5NN14 PTHR24228:SF9 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR 25-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002620.1|UniProtKB=W5M3X5 W5M3X5 PTHR16021:SF9 MANSC DOMAIN CONTAINING PROTEIN 1 CHROMOSOME 11 OPEN READING FRAME 24 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010938.1|UniProtKB=W5MYF5 W5MYF5 PTHR10218:SF67 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of stimulus#GO:0051606;nervous system process#GO:0050877;cell communication#GO:0007154;visual perception#GO:0007601;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;response to abiotic stimulus#GO:0009628;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Enkephalin release#P05913>G-Protein (i)#P05974;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gtalpha#P00760;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 LEPOC|Ensembl=ENSLOCG00000006994.1|UniProtKB=W5MJC0 W5MJC0 PTHR11827:SF46 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;monoatomic cation transport#GO:0006812;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cell communication#GO:0007154;cellular component organization#GO:0016043;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;potassium ion import across plasma membrane#GO:1990573 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002698.1|UniProtKB=W5M464 W5M464 PTHR10024:SF175 SYNAPTOTAGMIN C2 DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001118.1|UniProtKB=W5LYQ5 W5LYQ5 PTHR10131:SF152 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 6 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to lipopolysaccharide#GO:0071222;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;positive regulation of NF-kappaB transcription factor activity#GO:0051092;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of macromolecule biosynthetic process#GO:0010556;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;defense response#GO:0006952;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;lipopolysaccharide-mediated signaling pathway#GO:0031663;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;defense response to symbiont#GO:0140546;response to lipopolysaccharide#GO:0032496;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 p53 pathway#P00059>TRAF#P04620;p38 MAPK pathway#P05918>TRAF6#P06038;Toll receptor signaling pathway#P00054>TRAF6#P01371;Apoptosis signaling pathway#P00006>TRAF2#P00306 LEPOC|Ensembl=ENSLOCG00000015122.1|UniProtKB=W5NDA4 W5NDA4 PTHR14383:SF2 SWAP-70 RECOMBINASE DIFFERENTIALLY EXPRESSED IN FDCP 6 HOMOLOG cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007522.1|UniProtKB=W5ML85 W5ML85 PTHR24092:SF46 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ID ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227